Paul A. Khavari - Publications

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Molecular Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ji AL, Rubin AJ, Thrane K, Jiang S, Reynolds DL, Meyers RM, Guo MG, George BM, Mollbrink A, Bergenstråhle J, Larsson L, Bai Y, Zhu B, Bhaduri A, Meyers JM, ... ... Khavari PA, et al. Multimodal Analysis of Composition and Spatial Architecture in Human Squamous Cell Carcinoma. Cell. PMID 32579974 DOI: 10.1016/J.Cell.2020.05.039  0.346
2020 Carter AC, Xu J, Nakamoto MY, Wei Y, Zarnegar BJ, Shi Q, Broughton JP, Ransom RC, Salhotra A, Nagaraja SD, Li R, Dou DR, Yost KE, Cho SW, Mistry A, ... ... Khavari PA, et al. Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. Elife. 9. PMID 32379046 DOI: 10.7554/Elife.54508  0.305
2019 Che Y, Siprashvili Z, Kovalski JR, Jiang T, Wozniak G, Elcavage L, Khavari PA. KRAS regulation by small non-coding RNAs and SNARE proteins. Nature Communications. 10: 5118. PMID 31712554 DOI: 10.1038/S41467-019-13106-4  0.32
2019 Yang X, Bayat V, DiDonato N, Zhao Y, Zarnegar B, Siprashvili Z, Lopez-Pajares V, Sun T, Tao S, Li C, Rump A, Khavari P, Lu B. Genetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis. Human Molecular Genetics. PMID 31628467 DOI: 10.1093/Hmg/Ddz251  0.357
2019 Ren L, Ding S, Song Y, Li B, Ramanathan M, Co J, Amieva MR, Khavari PA, Greenberg HB. Profiling of rotavirus 3'UTR-binding proteins reveals the ATP synthase subunit ATP5B as a host factor that supports late-stage virus replication. The Journal of Biological Chemistry. PMID 30770472 DOI: 10.1074/Jbc.Ra118.006004  0.302
2018 Rubin AJ, Parker KR, Satpathy AT, Qi Y, Wu B, Ong AJ, Mumbach MR, Ji AL, Kim DS, Cho SW, Zarnegar BJ, Greenleaf WJ, Chang HY, Khavari PA. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell. PMID 30580963 DOI: 10.1016/J.Cell.2018.11.022  0.362
2018 Pattison JM, Melo SP, Piekos SN, Torkelson JL, Bashkirova E, Mumbach MR, Rajasingh C, Zhen HH, Li L, Liaw E, Alber D, Rubin AJ, Shankar G, Bao X, Chang HY, ... Khavari PA, et al. Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment. Nature Genetics. PMID 30397335 DOI: 10.1038/S41588-018-0263-0  0.333
2018 Ramanathan M, Majzoub K, Rao DS, Neela PH, Zarnegar BJ, Mondal S, Roth JG, Gai H, Kovalski JR, Siprashvili Z, Palmer TD, Carette JE, Khavari PA. RNA-protein interaction detection in living cells. Nature Methods. PMID 29400715 DOI: 10.1038/Nmeth.4601  0.31
2017 Ransohoff JD, Wei Y, Khavari PA. The functions and unique features of long intergenic non-coding RNA. Nature Reviews. Molecular Cell Biology. PMID 29138516 DOI: 10.1038/Nrm.2017.104  0.307
2017 Mumbach MR, Satpathy AT, Boyle EA, Dai C, Gowen BG, Cho SW, Nguyen ML, Rubin AJ, Granja JM, Kazane KR, Wei Y, Nguyen T, Greenside PG, Corces MR, Tycko J, ... ... Khavari PA, et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nature Genetics. PMID 28945252 DOI: 10.1038/Ng.3963  0.353
2017 Bao X, Siprashvili Z, Zarnegar BJ, Shenoy RM, Rios EJ, Nady N, Qu K, Mah A, Webster DE, Rubin AJ, Wozniak GG, Tao S, Wysocka J, Khavari PA. CSNK1a1 Regulates PRMT1 to Maintain the Progenitor State in Self-Renewing Somatic Tissue. Developmental Cell. PMID 28943242 DOI: 10.1016/J.Devcel.2017.08.021  0.358
2017 Rubin AJ, Barajas BC, Furlan-Magaril M, Lopez-Pajares V, Mumbach MR, Howard I, Kim DS, Boxer LD, Cairns J, Spivakov M, Wingett SW, Shi M, Zhao Z, Greenleaf WJ, Kundaje A, ... ... Khavari PA, et al. Lineage-specific dynamic and pre-established enhancer-promoter contacts cooperate in terminal differentiation. Nature Genetics. PMID 28805829 DOI: 10.1038/Ng.3935  0.361
2017 Gong X, Siprashvili Z, Eminaga O, Shen Z, Sato Y, Kume H, Homma Y, Ogawa S, Khavari PA, Pollack JR, Brooks JD. Novel lincRNA SLINKY is a prognostic biomarker in kidney cancer. Oncotarget. 8: 18657-18669. PMID 28423633 DOI: 10.18632/Oncotarget.15703  0.318
2017 Ransohoff J, Ramanathan M, Khavari P. 408 Discovery of differential RNA binding and regulation by the APOL4 protein to disease-linked psoriasis CDSN gene variants using RaPID Journal of Investigative Dermatology. 137: S71. DOI: 10.1016/J.Jid.2017.02.427  0.333
2017 Ramanathan M, Majzoub K, Roth J, Gai H, Palmer T, Carette J, Khavari P. 123 RNA-protein interaction detection (RaPID) in living cells uncovers post-transcriptional regulation in carcinogenesis Journal of Investigative Dermatology. 137: S21. DOI: 10.1016/J.Jid.2017.02.137  0.335
2016 Winge MC, Ohyama B, Dey CN, Boxer LM, Li W, Ehsani-Chimeh N, Truong AK, Wu D, Armstrong AW, Makino T, Davidson M, Starcevic D, Kislat A, Nguyen NT, Hashimoto T, ... ... Khavari PA, et al. RAC1 activation drives pathologic interactions between the epidermis and immune cells. The Journal of Clinical Investigation. PMID 27294528 DOI: 10.1172/Jci85738  0.377
2016 Flynn RA, Do BT, Rubin AJ, Calo E, Lee B, Kuchelmeister H, Rale M, Chu C, Kool ET, Wysocka J, Khavari PA, Chang HY. 7SK-BAF axis controls pervasive transcription at enhancers. Nature Structural & Molecular Biology. PMID 26878240 DOI: 10.1038/Nsmb.3176  0.341
2016 Lopez-Pajares V, Barajas B, Rubin A, Khavari P. 335 Regulation of epidermal differentiation by MAF and MAFB Journal of Investigative Dermatology. 136: S59. DOI: 10.1016/J.Jid.2016.02.367  0.301
2015 Bao X, Rubin AJ, Qu K, Zhang J, Giresi PG, Chang HY, Khavari PA. A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63. Genome Biology. 16: 284. PMID 26683334 DOI: 10.1186/S13059-015-0840-9  0.315
2015 Bhaduri A, Ungewickell A, Boxer LD, Lopez-Pajares V, Zarnegar BJ, Khavari PA. Network Analysis Identifies Mitochondrial Regulation of Epidermal Differentiation by MPZL3 and FDXR. Developmental Cell. 35: 444-57. PMID 26609959 DOI: 10.1016/J.Devcel.2015.10.023  0.325
2015 Siprashvili Z, Webster DE, Johnston D, Shenoy RM, Ungewickell AJ, Bhaduri A, Flockhart R, Zarnegar BJ, Che Y, Meschi F, Puglisi JD, Khavari PA. The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer. Nature Genetics. PMID 26595770 DOI: 10.1038/Ng.3452  0.308
2015 Sun BK, Boxer LD, Ransohoff JD, Siprashvili Z, Qu K, Lopez-Pajares V, Hollmig ST, Khavari PA. CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation. Genes & Development. 29: 2225-30. PMID 26545810 DOI: 10.1101/Gad.267708.115  0.364
2015 Ungewickell A, Bhaduri A, Rios E, Reuter J, Lee CS, Mah A, Zehnder A, Ohgami R, Kulkarni S, Armstrong R, Weng WK, Gratzinger D, Tavallaee M, Rook A, Snyder M, ... ... Khavari PA, et al. Genomic analysis of mycosis fungoides and Sézary syndrome identifies recurrent alterations in TNFR2. Nature Genetics. PMID 26258847 DOI: 10.1038/Ng.3370  0.33
2015 Lopez-Pajares V, Qu K, Zhang J, Webster DE, Barajas BC, Siprashvili Z, Zarnegar BJ, Boxer LD, Rios EJ, Tao S, Kretz M, Khavari PA. A LncRNA-MAF:MAFB transcription factor network regulates epidermal differentiation. Developmental Cell. 32: 693-706. PMID 25805135 DOI: 10.1016/J.Devcel.2015.01.028  0.36
2015 Zehnder A, Lee B, Neela P, Khavari P. Abstract 5137: IQGAP1, an ERK1/2 MAPK scaffold, is an oncogenic target in canine melanoma Cancer Research. 75: 5137-5137. DOI: 10.1158/1538-7445.Am2015-5137  0.385
2014 Sun BK, Siprashvili Z, Khavari PA. Advances in skin grafting and treatment of cutaneous wounds. Science (New York, N.Y.). 346: 941-5. PMID 25414301 DOI: 10.1126/Science.1253836  0.317
2014 Marques Howarth M, Simpson D, Ngok SP, Nieves B, Chen R, Siprashvili Z, Vaka D, Breese MR, Crompton BD, Alexe G, Hawkins DS, Jacobson D, Brunner AL, West R, Mora J, ... ... Khavari P, et al. Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. The Journal of Clinical Investigation. 124: 5275-90. PMID 25401475 DOI: 10.1172/Jci72124  0.392
2014 Boxer LD, Barajas B, Tao S, Zhang J, Khavari PA. ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes. Genes & Development. 28: 2013-26. PMID 25228645 DOI: 10.1101/Gad.246579.114  0.365
2014 Lee CS, Bhaduri A, Mah A, Johnson WL, Ungewickell A, Aros CJ, Nguyen CB, Rios EJ, Siprashvili Z, Straight A, Kim J, Aasi SZ, Khavari PA. Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma. Nature Genetics. 46: 1060-2. PMID 25194279 DOI: 10.1038/Ng.3091  0.34
2014 Zheng GX, Do BT, Webster DE, Khavari PA, Chang HY. Dicer-microRNA-Myc circuit promotes transcription of hundreds of long noncoding RNAs. Nature Structural & Molecular Biology. 21: 585-90. PMID 24929436 DOI: 10.1038/Nsmb.2842  0.326
2014 Webster DE, Barajas B, Bussat RT, Yan KJ, Neela PH, Flockhart RJ, Kovalski J, Zehnder A, Khavari PA. Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition. Genome Research. 24: 751-60. PMID 24443471 DOI: 10.1101/Gr.166231.113  0.351
2014 Gocke CB, Wang Q, McMillan R, Penchev V, Sage J, Khavari PA, Matsui W. Inhibiting Oncogenic RAS in Multiple Myeloma By Targeting Scaffold-ERK Interactions Blood. 124: 2089-2089. DOI: 10.1182/Blood.V124.21.2089.2089  0.324
2013 Sarin KY, Sun BK, Bangs CD, Cherry A, Swetter SM, Kim J, Khavari PA. Activating HRAS mutation in agminated Spitz nevi arising in a nevus spilus. Jama Dermatology. 149: 1077-81. PMID 23884457 DOI: 10.1001/Jamadermatol.2013.4745  0.317
2013 Jameson KL, Mazur PK, Zehnder AM, Zhang J, Zarnegar B, Sage J, Khavari PA. IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors. Nature Medicine. 19: 626-30. PMID 23603816 DOI: 10.1038/Nm.3165  0.324
2013 Bao X, Tang J, Lopez-Pajares V, Tao S, Qu K, Crabtree GR, Khavari PA. ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4. Cell Stem Cell. 12: 193-203. PMID 23395444 DOI: 10.1016/J.Stem.2012.12.014  0.541
2013 Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, ... ... Khavari PA, et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. Nature. 493: 231-5. PMID 23201690 DOI: 10.1038/Nature11661  0.343
2013 Lopez-Pajares V, Yan K, Zarnegar BJ, Jameson KL, Khavari PA. Genetic pathways in disorders of epidermal differentiation. Trends in Genetics : Tig. 29: 31-40. PMID 23141808 DOI: 10.1016/J.Tig.2012.10.005  0.353
2013 Sun BK, Saggini A, Sarin KY, Kim J, Benjamin L, LeBoit PE, Khavari PA. Mosaic activating RAS mutations in nevus sebaceus and nevus sebaceus syndrome. The Journal of Investigative Dermatology. 133: 824-7. PMID 23096709 DOI: 10.1038/Jid.2012.377  0.319
2012 Lee CS, Ungewickell A, Bhaduri A, Qu K, Webster DE, Armstrong R, Weng WK, Aros CJ, Mah A, Chen RO, Lin M, Sundram U, Chang HY, Kretz M, Kim YH, ... Khavari PA, et al. Transcriptome sequencing in Sezary syndrome identifies Sezary cell and mycosis fungoides-associated lncRNAs and novel transcripts. Blood. 120: 3288-97. PMID 22936659 DOI: 10.1182/Blood-2012-04-423061  0.404
2012 Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA. Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63. American Journal of Human Genetics. 91: 435-43. PMID 22922031 DOI: 10.1016/J.Ajhg.2012.07.007  0.346
2012 Sen GL, Boxer LD, Webster DE, Bussat RT, Qu K, Zarnegar BJ, Johnston D, Siprashvili Z, Khavari PA. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation. Developmental Cell. 22: 669-77. PMID 22364861 DOI: 10.1016/J.Devcel.2011.12.001  0.385
2012 Kretz M, Webster DE, Flockhart RJ, Lee CS, Zehnder A, Lopez-Pajares V, Qu K, Zheng GX, Chow J, Kim GE, Rinn JL, Chang HY, Siprashvili Z, Khavari PA. Suppression of progenitor differentiation requires the long noncoding RNA ANCR. Genes & Development. 26: 338-43. PMID 22302877 DOI: 10.1101/Gad.182121.111  0.351
2010 Ridky TW, Chow JM, Wong DJ, Khavari PA. Invasive three-dimensional organotypic neoplasia from multiple normal human epithelia. Nature Medicine. 16: 1450-5. PMID 21102459 DOI: 10.1038/Nm.2265  0.329
2010 Siprashvili Z, Nguyen NT, Bezchinsky MY, Marinkovich MP, Lane AT, Khavari PA. Long-term type VII collagen restoration to human epidermolysis bullosa skin tissue. Human Gene Therapy. 21: 1299-310. PMID 20497034 DOI: 10.1089/Hum.2010.023  0.327
2010 Ridky TW, Khavari PA. The hair follicle bulge stem cell niche resists transformation by the hedgehog pathway. Cell Stem Cell. 6: 292-4. PMID 20362530 DOI: 10.1016/J.Stem.2010.03.009  0.321
2010 Sen GL, Reuter JA, Webster DE, Zhu L, Khavari PA. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature. 463: 563-7. PMID 20081831 DOI: 10.1038/Nature08683  0.326
2009 Reuter JA, Ortiz-Urda S, Kretz M, Garcia J, Scholl FA, Pasmooij AM, Cassarino D, Chang HY, Khavari PA. Modeling inducible human tissue neoplasia identifies an extracellular matrix interaction network involved in cancer progression. Cancer Cell. 15: 477-88. PMID 19477427 DOI: 10.1016/J.Ccr.2009.04.002  0.324
2009 Dumesic PA, Scholl FA, Barragan DI, Khavari PA. Erk1/2 MAP kinases are required for epidermal G2/M progression. The Journal of Cell Biology. 185: 409-22. PMID 19414607 DOI: 10.1083/Jcb.200804038  0.366
2009 Scholl FA, Dumesic PA, Barragan DI, Harada K, Charron J, Khavari PA. Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia. Cancer Research. 69: 3772-8. PMID 19383924 DOI: 10.1158/0008-5472.Can-08-1963  0.352
2009 Scholl FA, Dumesic PA, Barragan DI, Charron J, Khavari PA. Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin. Oncogene. 28: 1485-95. PMID 19198628 DOI: 10.1038/Onc.2008.459  0.341
2008 Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/Gad.1673508  0.348
2007 Waterman EA, Sakai N, Nguyen NT, Horst BA, Veitch DP, Dey CN, Ortiz-Urda S, Khavari PA, Marinkovich MP. A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation. Cancer Research. 67: 4264-70. PMID 17483338 DOI: 10.1158/0008-5472.Can-06-4141  0.334
2007 Zhang JY, Adams AE, Ridky TW, Tao S, Khavari PA. Tumor necrosis factor receptor 1/c-Jun-NH2-kinase signaling promotes human neoplasia. Cancer Research. 67: 3827-34. PMID 17440097 DOI: 10.1158/0008-5472.Can-06-4017  0.366
2007 Scholl FA, Dumesic PA, Barragan DI, Harada K, Bissonauth V, Charron J, Khavari PA. Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia. Developmental Cell. 12: 615-29. PMID 17419998 DOI: 10.1016/J.Devcel.2007.03.009  0.371
2007 Truong AB, Khavari PA. Control of keratinocyte proliferation and differentiation by p63. Cell Cycle (Georgetown, Tex.). 6: 295-9. PMID 17264679 DOI: 10.4161/Cc.6.3.3753  0.306
2006 Truong AB, Kretz M, Ridky TW, Kimmel R, Khavari PA. p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes & Development. 20: 3185-97. PMID 17114587 DOI: 10.1101/Gad.1463206  0.316
2006 Reuter JA, Khavari PA. Use of conditionally active ras fusion proteins to study epidermal growth, differentiation, and neoplasia. Methods in Enzymology. 407: 691-702. PMID 16757362 DOI: 10.1016/S0076-6879(05)07054-0  0.309
2006 Adams AE, Chudnovsky Y, Khavari PA. Oxygen deprivation provokes melanoma. Nature Medicine. 12: 168-9. PMID 16462795 DOI: 10.1038/Nm0206-168  0.732
2005 Harada K, Truong AB, Cai T, Khavari PA. The class II phosphoinositide 3-kinase C2beta is not essential for epidermal differentiation. Molecular and Cellular Biology. 25: 11122-30. PMID 16314532 DOI: 10.1128/Mcb.25.24.11122-11130.2005  0.334
2005 Scholl FA, Dumesic PA, Khavari PA. Effects of active MEK1 expression in vivo. Cancer Letters. 230: 1-5. PMID 16253755 DOI: 10.1016/J.Canlet.2004.12.013  0.418
2005 Chudnovsky Y, Adams AE, Robbins PB, Lin Q, Khavari PA. Use of human tissue to assess the oncogenic activity of melanoma-associated mutations. Nature Genetics. 37: 745-9. PMID 15951821 DOI: 10.1038/Ng1586  0.756
2005 Chudnovsky Y, Khavari PA, Adams AE. Melanoma genetics and the development of rational therapeutics. The Journal of Clinical Investigation. 115: 813-24. PMID 15841168 DOI: 10.1172/Jci24808  0.744
2005 Ortiz-Urda S, Garcia J, Green CL, Chen L, Lin Q, Veitch DP, Sakai LY, Lee H, Marinkovich MP, Khavari PA. Type VII collagen is required for Ras-driven human epidermal tumorigenesis. Science (New York, N.Y.). 307: 1773-6. PMID 15774758 DOI: 10.1126/Science.1106209  0.355
2005 Zhang JY, Tao S, Kimmel R, Khavari PA. CDK4 regulation by TNFR1 and JNK is required for NF-kappaB-mediated epidermal growth control. The Journal of Cell Biology. 168: 561-6. PMID 15699216 DOI: 10.1083/Jcb.200411060  0.392
2004 Scholl FA, Dumesic PA, Khavari PA. Mek1 alters epidermal growth and differentiation. Cancer Research. 64: 6035-40. PMID 15342384 DOI: 10.1158/0008-5472.Can-04-0017  0.332
2004 Khavari PA. Profiling epithelial stem cells. Nature Biotechnology. 22: 393-4. PMID 15060550 DOI: 10.1038/Nbt0404-393  0.309
2004 Ridky TW, Khavari PA. Pathways sufficient to induce epidermal carcinogenesis. Cell Cycle (Georgetown, Tex.). 3: 621-4. PMID 15044848 DOI: 10.4161/Cc.3.5.860  0.408
2004 Green CL, Khavari PA. Targets for molecular therapy of skin cancer. Seminars in Cancer Biology. 14: 63-9. PMID 14757536 DOI: 10.1016/J.Semcancer.2003.11.007  0.383
2004 Siprashvili Z, Khavari PA. Lentivectors for regulated and reversible cutaneous gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 9: 93-100. PMID 14741782 DOI: 10.1016/J.Ymthe.2003.09.016  0.365
2004 Zhang JY, Green CL, Tao S, Khavari PA. NF-kappaB RelA opposes epidermal proliferation driven by TNFR1 and JNK. Genes & Development. 18: 17-22. PMID 14724177 DOI: 10.1101/Gad.1160904  0.401
2003 Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Calos MP, Khavari PA. PhiC31 integrase-mediated nonviral genetic correction of junctional epidermolysis bullosa. Human Gene Therapy. 14: 923-8. PMID 12828862 DOI: 10.1089/104303403765701204  0.341
2003 Ortiz-Urda S, Lin Q, Yant SR, Keene D, Kay MA, Khavari PA. Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer. Gene Therapy. 10: 1099-104. PMID 12808440 DOI: 10.1038/Sj.Gt.3301978  0.363
2003 Hinata K, Gervin AM, Jennifer Zhang Y, Khavari PA. Divergent gene regulation and growth effects by NF-kappa B in epithelial and mesenchymal cells of human skin. Oncogene. 22: 1955-64. PMID 12673201 DOI: 10.1038/Sj.Onc.1206198  0.758
2003 Dajee M, Lazarov M, Zhang JY, Cai T, Green CL, Russell AJ, Marinkovich MP, Tao S, Lin Q, Kubo Y, Khavari PA. NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia. Nature. 421: 639-43. PMID 12571598 DOI: 10.1038/Nature01283  0.408
2003 Ortiz-Urda S, Lin Q, Green CL, Keene DR, Marinkovich MP, Khavari PA. Injection of genetically engineered fibroblasts corrects regenerated human epidermolysis bullosa skin tissue. The Journal of Clinical Investigation. 111: 251-5. PMID 12531881 DOI: 10.1172/Jci17193  0.304
2002 Cai T, Nishida K, Hirano T, Khavari PA. Gab1 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation. The Journal of Cell Biology. 159: 103-12. PMID 12370245 DOI: 10.1083/Jcb.200205017  0.317
2002 Lazarov M, Kubo Y, Cai T, Dajee M, Tarutani M, Lin Q, Fang M, Tao S, Green CL, Khavari PA. CDK4 coexpression with Ras generates malignant human epidermal tumorigenesis. Nature Medicine. 8: 1105-14. PMID 12357246 DOI: 10.1038/Nm779  0.342
2002 Ortiz-Urda S, Thyagarajan B, Keene DR, Lin Q, Fang M, Calos MP, Khavari PA. Stable nonviral genetic correction of inherited human skin disease Nature Medicine. 8: 1166-1170. PMID 12244305 DOI: 10.1038/Nm766  0.342
2001 Baek SC, Lin Q, Robbins PB, Fan H, Khavari PA. Sustainable systemic delivery via a single injection of lentivirus into human skin tissue Human Gene Therapy. 12: 1551-1558. PMID 11506697 DOI: 10.1089/10430340152480276  0.343
2001 Robbins PB, Sheu SM, Goodnough JB, Khavari PA. Impact of laminin 5 β3 gene versus protein replacement on gene expression patterns in junctional epidermolysis bullosa Human Gene Therapy. 12: 1443-1448. PMID 11485635 DOI: 10.1089/104303401750298599  0.322
2001 Khavari PA. Genetic correction of inherited epidermal disorders. Human Gene Therapy. 11: 2277-82. PMID 11084686 DOI: 10.1089/104303400750035816  0.364
2000 Seitz CS, Deng H, Hinata K, Lin Q, Khavari PA. Nuclear factor kappaB subunits induce epithelial cell growth arrest. Cancer Research. 60: 4085-92. PMID 10945614  0.759
2000 Seitz CS, Freiberg RA, Hinata K, Khavari PA. NF-kappaB determines localization and features of cell death in epidermis. The Journal of Clinical Investigation. 105: 253-60. PMID 10675350 DOI: 10.1172/Jci7630  0.756
1999 Fan H, Khavari PA. Sonic hedgehog opposes epithelial cell cycle arrest. The Journal of Cell Biology. 147: 71-6. PMID 10508856 DOI: 10.1083/Jcb.147.1.71  0.367
1998 Deng H, Choate KA, Lin Q, Khavari PA. High-efficiency gene transfer and pharmacologic selection of genetically engineered human keratinocytes Biotechniques. 25: 274-280. PMID 9714888 DOI: 10.2144/98252Gt02  0.35
1998 Seitz CS, Lin Q, Deng H, Khavari PA. Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB. Proceedings of the National Academy of Sciences of the United States of America. 95: 2307-12. PMID 9482881 DOI: 10.1073/Pnas.95.5.2307  0.412
1998 Khavari PA. Therapeutic gene delivery to the skin. Molecular Medicine Today. 3: 533-8. PMID 9449124 DOI: 10.1016/S1357-4310(97)01143-X  0.331
1998 Deng H, Lin Q, Khavari PA. Sustainable cutaneous gene delivery. Nature Biotechnology. 15: 1388-91. PMID 9415892 DOI: 10.1038/Nbt1297-1388  0.364
1998 Fan H, Khavari P. Sonic hedgehog regulates keratinocyte differentiation gene expression and cell cycle progression Journal of Dermatological Science. 16: S14. DOI: 10.1016/S0923-1811(98)83083-1  0.374
1997 Choate KA, Khavari PA. Direct cutaneous gene delivery in a human genetic skin disease. Human Gene Therapy. 8: 1659-65. PMID 9322868 DOI: 10.1089/Hum.1997.8.14-1659  0.353
1997 Fan H, Oro AE, Scott MP, Khavari PA. Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nature Medicine. 3: 788-92. PMID 9212109 DOI: 10.1038/Nm0797-788  0.408
1997 Choate KA, Khavari PA. Sustainability of keratinocyte gene transfer and cell survival in vivo. Human Gene Therapy. 8: 895-901. PMID 9195211 DOI: 10.1089/Hum.1997.8.8-895  0.361
1997 Freiberg RA, Choate KA, Deng H, Alperin ES, Shapiro LJ, Khavari PA. A model of corrective gene transfer in X-linked ichthyosis. Human Molecular Genetics. 6: 927-33. PMID 9175741 DOI: 10.1093/Hmg/6.6.927  0.372
1997 Freiberg RA, Spencer DM, Choate KA, Duh HJ, Schreiber SL, Crabtree GR, Khavari PA. Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts. The Journal of Investigative Dermatology. 108: 215-9. PMID 9008237 DOI: 10.1111/1523-1747.Ep12334273  0.517
1996 Choate KA, Kinsella TM, Williams ML, Nolan GP, Khavari PA. Transglutaminase 1 delivery to lamellar ichthyosis keratinocytes. Human Gene Therapy. 7: 2247-53. PMID 8953315 DOI: 10.1089/Hum.1996.7.18-2247  0.364
1996 Freiberg RA, Spencer DM, Choate KA, Peng PD, Schreiber SL, Crabtree GR, Khavari PA. Specific triggering of the Fas signal transduction pathway in normal human keratinocytes. The Journal of Biological Chemistry. 271: 31666-9. PMID 8940187 DOI: 10.1074/Jbc.271.49.31666  0.451
1996 Choate KA, Medalie DA, Morgan JR, Khavari PA. Corrective gene transfer in the human skin disorder lamellar ichthyosis Nature Medicine. 2: 1263-1267. PMID 8898758 DOI: 10.1038/Nm1196-1263  0.348
1996 Wang W, Côté J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL, Crabtree GR. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. The Embo Journal. 15: 5370-5382. DOI: 10.1002/J.1460-2075.1996.Tb00921.X  0.733
1994 Kwon H, Imbalzano AN, Khavari PA, Kingston RE, Green MR. Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex Nature. 370: 477-481. PMID 8047169 DOI: 10.1038/370477A0  0.326
1994 Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell. 79: 119-30. PMID 7923370 DOI: 10.1016/0092-8674(94)90405-7  0.566
1994 Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J. brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator. Developmental Biology. 161: 229-42. PMID 7904967 DOI: 10.1006/Dbio.1994.1023  0.517
1993 Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature. 366: 170-4. PMID 8232556 DOI: 10.1038/366170A0  0.524
1991 Mendel DB, Khavari PA, Conley PB, Graves MK, Hansen LP, Admon A, Crabtree GR. Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein. Science (New York, N.Y.). 254: 1762-7. PMID 1763325 DOI: 10.1126/Science.1763325  0.481
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