Frederic Kaye - Publications

The George Washington University, Washington, DC, United States 
Genetics, Oncology, Molecular Biology

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jiang Y, Gao R, Cao C, Forbes L, Li J, Freeberg S, Fredenburg KM, Justice JM, Silver NL, Wu L, Varma S, West R, Licht JD, Zajac-Kaye M, Kentsis A, ... Kaye FJ, et al. MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma. Oral Oncology. 98: 147-155. PMID 31606723 DOI: 10.1016/j.oraloncology.2019.09.005  0.32
2019 Kellish P, Shabashvili D, Rahman MM, Nawab A, Guijarro MV, Zhang M, Cao C, Moussatche N, Boyle T, Antonia S, Reinhard M, Hartzell C, Jantz M, Mehta HJ, McFadden G, ... Kaye FJ, et al. Oncolytic virotherapy for small-cell lung cancer induces immune infiltration and prolongs survival. The Journal of Clinical Investigation. 130. PMID 31033480 DOI: 10.1172/JCI121323  0.32
2018 Gopalan PK, Villegas AG, Cao C, Pinder-Schenck M, Chiappori A, Hou W, Zajac-Kaye M, Ivey AM, Kaye FJ. CDK4/6 inhibition stabilizes disease in patients with p16-null non-small cell lung cancer and is synergistic with mTOR inhibition. Oncotarget. 9: 37352-37366. PMID 30647837 DOI: 10.18632/oncotarget.26424  0.32
2017 Chen M, Maeng K, Nawab A, Francois RA, Bray JK, Reinhard MK, Boye SL, Hauswirth WW, Kaye FJ, Aslanidi GV, Srivastava A, Zajac-Kaye M. Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-optimized AAV8 Vectors. Human Gene Therapy Methods. PMID 28125909 DOI: 10.1089/hgtb.2016.089  0.32
2015 François RA, Maeng K, Nawab A, Kaye FJ, Hochwald SN, Zajac-Kaye M. Targeting Focal Adhesion Kinase and Resistance to mTOR Inhibition in Pancreatic Neuroendocrine Tumors. Journal of the National Cancer Institute. 107. PMID 25971297 DOI: 10.1093/jnci/djv123  0.32
2015 Cao C, Gao R, Zhang M, Amelio AL, Fallahi M, Chen Z, Gu Y, Hu C, Welsh EA, Engel BE, Haura EB, Cress WD, Wu L, Zajac-Kaye M, Kaye FJ. Role of LKB1-CRTC1 on glycosylated COX-2 and response to COX-2 inhibition in lung cancer. Journal of the National Cancer Institute. 107: 358. PMID 25465874 DOI: 10.1093/jnci/dju358  0.32
2014 Gao R, Cao C, Zhang M, Lopez MC, Yan Y, Chen Z, Mitani Y, Zhang L, Zajac-Kaye M, Liu B, Wu L, Renne R, Baker HV, El-Naggar A, Kaye FJ. A unifying gene signature for adenoid cystic cancer identifies parallel MYB-dependent and MYB-independent therapeutic targets. Oncotarget. 5: 12528-42. PMID 25587024  0.32
2014 Amelio AL, Fallahi M, Schaub FX, Zhang M, Lawani MB, Alperstein AS, Southern MR, Young BM, Wu L, Zajac-Kaye M, Kaye FJ, Cleveland JL, Conkright MD. CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement. Proceedings of the National Academy of Sciences of the United States of America. 111: E3260-8. PMID 25071166 DOI: 10.1073/pnas.1319176111  0.32
2014 Lee HS, Chen M, Kim JH, Kim WH, Ahn S, Maeng K, Allegra CJ, Kaye FJ, Hochwald SN, Zajac-Kaye M. Analysis of 320 gastroenteropancreatic neuroendocrine tumors identifies TS expression as independent biomarker for survival. International Journal of Cancer. Journal International Du Cancer. 135: 128-37. PMID 24347111 DOI: 10.1002/ijc.28675  0.32
2012 Chen M, Shabashvili D, Nawab A, Yang SX, Dyer LM, Brown KD, Hollingshead M, Hunter KW, Kaye FJ, Hochwald SN, Marquez VE, Steeg P, Zajac-Kaye M. DNA methyltransferase inhibitor, zebularine, delays tumor growth and induces apoptosis in a genetically engineered mouse model of breast cancer. Molecular Cancer Therapeutics. 11: 370-82. PMID 22203734 DOI: 10.1158/1535-7163.MCT-11-0458  0.32
2010 Chen M, Voeller D, Marquez VE, Kaye FJ, Steeg PS, Giaccone G, Zajac-Kaye M. Enhanced growth inhibition by combined DNA methylation/HDAC inhibitors in lung tumor cells with silenced CDKN2A. International Journal of Oncology. 37: 963-71. PMID 20811718  0.32
2010 Anzick SL, Chen WD, Park Y, Meltzer P, Bell D, El-Naggar AK, Kaye FJ. Unfavorable prognosis of CRTC1-MAML2 positive mucoepidermoid tumors with CDKN2A deletions. Genes, Chromosomes & Cancer. 49: 59-69. PMID 19827123 DOI: 10.1002/gcc.20719  0.32
2006 Komiya T, Park Y, Modi S, Coxon AB, Oh H, Kaye FJ. Sustained expression of Mect1-Maml2 is essential for tumor cell growth in salivary gland cancers carrying the t(11;19) translocation. Oncogene. 25: 6128-32. PMID 16652146 DOI: 10.1038/sj.onc.1209627  0.32
2004 Rahman L, Voeller D, Rahman M, Lipkowitz S, Allegra C, Barrett JC, Kaye FJ, Zajac-Kaye M. Thymidylate synthase as an oncogene: a novel role for an essential DNA synthesis enzyme. Cancer Cell. 5: 341-51. PMID 15093541 DOI: 10.1016/S1535-6108(04)00080-7  0.32
2004 Rahman L, Bliskovski V, Kaye FJ, Zajac-Kaye M. Evolutionary conservation of a 2-kb intronic sequence flanking a tissue-specific alternative exon in the PTBP2 gene. Genomics. 83: 76-84. PMID 14667811  0.32
2003 Tonon G, Modi S, Wu L, Kubo A, Coxon AB, Komiya T, O'Neil K, Stover K, El-Naggar A, Griffin JD, Kirsch IR, Kaye FJ. t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway. Nature Genetics. 33: 208-13. PMID 12539049 DOI: 10.1038/ng1083  0.32
2000 Modi S, Kubo A, Oie H, Coxon AB, Rehmatulla A, Kaye FJ. Protein expression of the RB-related gene family and SV40 large T antigen in mesothelioma and lung cancer. Oncogene. 19: 4632-9. PMID 11030152 DOI: 10.1038/sj.onc.1203815  0.32
1999 Otterson GA, Modi S, Nguyen K, Coxon AB, Kaye FJ. Temperature-sensitive RB mutations linked to incomplete penetrance of familial retinoblastoma in 12 families. American Journal of Human Genetics. 65: 1040-6. PMID 10486322 DOI: 10.1086/302581  0.32
1998 Coxon AB, Ward JM, Geradts J, Otterson GA, Zajac-Kaye M, Kaye FJ. RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer. Oncogene. 17: 1625-8. PMID 9794240 DOI: 10.1038/sj.onc.1202381  0.32
1997 Otterson GA, Chen Wd, Coxon AB, Khleif SN, Kaye FJ. Incomplete penetrance of familial retinoblastoma linked to germ-line mutations that result in partial loss of RB function. Proceedings of the National Academy of Sciences of the United States of America. 94: 12036-40. PMID 9342358  0.32
1997 Chen WD, Otterson GA, Lipkowitz S, Khleif SN, Coxon AB, Kaye FJ. Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding. Oncogene. 14: 1243-8. PMID 9121775 DOI: 10.1038/sj.onc.1201096  0.32
1995 Otterson GA, Khleif SN, Chen W, Coxon AB, Kaye FJ. CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine. Oncogene. 11: 1211-6. PMID 7566983  0.32
1994 Kratzke RA, Otterson GA, Hogg A, Coxon AB, Geradts J, Cowell JK, Kaye FJ. Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors. Oncogene. 9: 1321-6. PMID 8152792  0.32
1994 Kim YW, Otterson GA, Kratzke RA, Coxon AB, Kaye FJ. Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein. Molecular and Cellular Biology. 14: 7256-64. PMID 7935440  0.32
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