Evangelia G. Kranias - Publications

University of Cincinnati, Cincinnati, OH 
Pharmacology, Molecular Biology, Animal Physiology Biology

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lam CK, Zhao W, Liu GS, Cai WF, Gardner G, Adly G, Kranias EG. HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 26553996 DOI: 10.1073/Pnas.1508760112  0.44
2015 Haghighi K, Pritchard TJ, Liu GS, Singh VP, Bidwell P, Lam CK, Vafiadaki E, Das P, Ma J, Kunduri S, Sanoudou D, Florea S, Vanderbilt E, Wang HS, Rubinstein J, ... ... Kranias EG, et al. Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. Journal of Molecular and Cellular Cardiology. PMID 26455482 DOI: 10.1016/J.Yjmcc.2015.10.004  0.44
2015 Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility. European Journal of Heart Failure. 17: 782-93. PMID 26177627 DOI: 10.1002/Ejhf.323  0.44
2015 Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, ... ... Kranias EG, et al. Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Nature Communications. 6: 6955. PMID 25923014 DOI: 10.1038/Ncomms7955  0.44
2015 Liu GS, Morales A, Vafiadaki E, Lam CK, Cai WF, Haghighi K, Adly G, Hershberger RE, Kranias EG. A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia. Cardiovascular Research. 107: 164-74. PMID 25852082 DOI: 10.1093/Cvr/Cvv127  0.44
2014 Haghighi K, Bidwell P, Kranias EG. Phospholamban interactome in cardiac contractility and survival: A new vision of an old friend. Journal of Molecular and Cellular Cardiology. 77: 160-7. PMID 25451386 DOI: 10.1016/J.Yjmcc.2014.10.005  0.44
2014 Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, ... ... Kranias EG, et al. Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2038-45. PMID 25023328 DOI: 10.1038/Mt.2014.127  0.44
2014 Vafiadaki E, Arvanitis DA, Papalouka V, Terzis G, Roumeliotis TI, Spengos K, Garbis SD, Manta P, Kranias EG, Sanoudou D. Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiation. The Febs Journal. 281: 3261-79. PMID 24860983 DOI: 10.1111/Febs.12859  0.44
2014 Rubinstein J, Lasko VM, Koch SE, Singh VP, Carreira V, Robbins N, Patel AR, Jiang M, Bidwell P, Kranias EG, Jones WK, Lorenz JN. Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance. American Journal of Physiology. Heart and Circulatory Physiology. 306: H574-84. PMID 24322617 DOI: 10.1152/Ajpheart.00854.2013  0.44
2014 Lipskaia L, Bobe R, Chen J, Turnbull IC, Lopez JJ, Merlet E, Jeong D, Karakikes I, Ross AS, Liang L, Mougenot N, Atassi F, Lompré AM, Tarzami ST, Kovacic JC, ... Kranias E, et al. Synergistic role of protein phosphatase inhibitor 1 and sarco/endoplasmic reticulum Ca2+ -ATPase in the acquisition of the contractile phenotype of arterial smooth muscle cells. Circulation. 129: 773-85. PMID 24249716 DOI: 10.1161/Circulationaha.113.002565  0.44
2013 Pritchard TJ, Kawase Y, Haghighi K, Anjak A, Cai W, Jiang M, Nicolaou P, Pylar G, Karakikes I, Rapti K, Rubinstein J, Hajjar RJ, Kranias EG. Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts. Plos One. 8: e80717. PMID 24312496 DOI: 10.1371/Journal.Pone.0080717  0.44
2013 Singh VP, Rubinstein J, Arvanitis DA, Ren X, Gao X, Haghighi K, Gilbert M, Iyer VR, Kim do H, Cho C, Jones K, Lorenz JN, Armstrong CF, Wang HS, Gyorke S, ... Kranias EG, et al. Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein. Journal of the American Heart Association. 2: e000460. PMID 24125847 DOI: 10.1161/Jaha.113.000460  0.44
2013 Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, et al. HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization. Antioxidants & Redox Signaling. 19: 1185-97. PMID 23919584 DOI: 10.1089/Ars.2012.5057  0.44
2013 Park CS, Chen S, Lee H, Cha H, Oh JG, Hong S, Han P, Ginsburg KS, Jin S, Park I, Singh VP, Wang HS, Franzini-Armstrong C, Park WJ, Bers DM, ... Kranias EG, et al. Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress. Basic Research in Cardiology. 108: 344. PMID 23553082 DOI: 10.1007/S00395-013-0344-2  0.44
2013 Fish KM, Ladage D, Kawase Y, Karakikes I, Jeong D, Ly H, Ishikawa K, Hadri L, Tilemann L, Muller-Ehmsen J, Samulski RJ, Kranias EG, Hajjar RJ. AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling. Circulation. Heart Failure. 6: 310-7. PMID 23271792 DOI: 10.1161/Circheartfailure.112.971325  0.44
2013 Lam CK, Zhao W, Cai W, Vafiadaki E, Florea SM, Ren X, Liu Y, Robbins N, Zhang Z, Zhou X, Jiang M, Rubinstein J, Jones WK, Kranias EG. Novel role of HAX-1 in ischemic injury protection involvement of heat shock protein 90. Circulation Research. 112: 79-89. PMID 22982986 DOI: 10.1161/Circresaha.112.279935  0.44
2012 Park CS, Cha H, Kwon EJ, Jeong D, Hajjar RJ, Kranias EG, Cho C, Park WJ, Kim DH. AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure Plos One. 7. PMID 22952658 DOI: 10.1371/Journal.Pone.0043282  0.44
2012 Florea S, Anjak A, Cai WF, Qian J, Vafiadaki E, Figueria S, Haghighi K, Rubinstein J, Lorenz J, Kranias EG. Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging. Basic Research in Cardiology. 107: 279. PMID 22777184 DOI: 10.1007/S00395-012-0279-Z  0.44
2012 Boncompagni S, Thomas M, Lopez JR, Allen PD, Yuan Q, Kranias EG, Franzini-Armstrong C, Perez CF. Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. Plos One. 7: e39962. PMID 22768324 DOI: 10.1371/Journal.Pone.0039962  0.44
2012 Cai WF, Pritchard T, Florea S, Lam CK, Han P, Zhou X, Yuan Q, Lehnart SE, Allen PD, Kranias EG. Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion. Cardiovascular Research. 94: 333-41. PMID 22411973 DOI: 10.1093/Cvr/Cvs119  0.44
2012 Haghighi K, Pritchard T, Bossuyt J, Waggoner JR, Yuan Q, Fan GC, Osinska H, Anjak A, Rubinstein J, Robbins J, Bers DM, Kranias EG. The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase. Journal of Molecular and Cellular Cardiology. 52: 773-82. PMID 22155237 DOI: 10.1016/J.Yjmcc.2011.11.012  0.44
2012 Sassi Y, Abi-Gerges A, Fauconnier J, Mougenot N, Reiken S, Haghighi K, Kranias EG, Marks AR, Lacampagne A, Engelhardt S, Hatem SN, Lompre AM, Hulot JS. Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1009-17. PMID 22090316 DOI: 10.1096/Fj.11-194027  0.44
2012 Pritchard TJ, Edes I, Kranias EG. Ca2+-ATPases Cell Physiology Source Book. 179-194. DOI: 10.1016/B978-0-12-387738-3.00013-5  0.44
2011 Altschafl BA, Arvanitis DA, Fuentes O, Yuan Q, Kranias EG, Valdivia HH. Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes. The Journal of Physiology. 589: 6063-80. PMID 22025663 DOI: 10.1113/Jphysiol.2011.215988  0.44
2011 Gaffin RD, Peña JR, Alves MS, Dias FA, Chowdhury SA, Heinrich LS, Goldspink PH, Kranias EG, Wieczorek DF, Wolska BM. Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein. Journal of Molecular and Cellular Cardiology. 51: 812-20. PMID 21840315 DOI: 10.1016/J.Yjmcc.2011.07.026  0.44
2011 Han P, Cai W, Wang Y, Lam CK, Arvanitis DA, Singh VP, Chen S, Zhang H, Zhang R, Cheng H, Kranias EG. Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1588-95. PMID 21742996 DOI: 10.1152/Ajpheart.01153.2010  0.44
2011 Qian J, Vafiadaki E, Florea SM, Singh VP, Song W, Lam CK, Wang Y, Yuan Q, Pritchard TJ, Cai W, Haghighi K, Rodriguez P, Wang HS, Sanoudou D, Fan GC, ... Kranias EG, et al. Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling. Circulation Research. 108: 1429-38. PMID 21493896 DOI: 10.1161/Circresaha.110.237644  0.44
2011 Goonasekera SA, Lam CK, Millay DP, Sargent MA, Hajjar RJ, Kranias EG, Molkentin JD. Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. The Journal of Clinical Investigation. 121: 1044-52. PMID 21285509 DOI: 10.1172/Jci43844  0.44
2011 Wang HS, Arvanitis DA, Dong M, Niklewski PJ, Zhao W, Lam CK, Kranias EG, Sanoudou D. SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts. Physiological Genomics. 43: 357-64. PMID 21266500 DOI: 10.1152/Physiolgenomics.00032.2010  0.44
2010 Hadri L, Bobe R, Kawase Y, Ladage D, Ishikawa K, Atassi F, Lebeche D, Kranias EG, Leopold JA, Lompré AM, Lipskaia L, Hajjar RJ. SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells Molecular Therapy. 18: 1284-1292. PMID 20461063 DOI: 10.1038/Mt.2010.77  0.44
2010 Lompré AM, Hajjar RJ, Harding SE, Kranias EG, Lohse MJ, Marks AR. Ca2+ cycling and new therapeutic approaches for heart failure. Circulation. 121: 822-30. PMID 20124124 DOI: 10.1161/Circulationaha.109.890954  0.44
2010 Salas MA, Valverde CA, Sánchez G, Said M, Rodriguez JS, Portiansky EL, Kaetzel MA, Dedman JR, Donoso P, Kranias EG, Mattiazzi A. The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury. Journal of Molecular and Cellular Cardiology. 48: 1298-306. PMID 20060004 DOI: 10.1016/J.Yjmcc.2009.12.015  0.44
2010 Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH. Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circulation Research. 106: 354-62. PMID 19959778 DOI: 10.1161/Circresaha.109.207423  0.44
2009 Zhao W, Waggoner JR, Zhang ZG, Lam CK, Han P, Qian J, Schroder PM, Mitton B, Kontrogianni-Konstantopoulos A, Robia SL, Kranias EG. The anti-apoptotic protein HAX-1 is a regulator of cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 106: 20776-81. PMID 19920172 DOI: 10.1073/Pnas.0906998106  0.44
2009 Liu Q, Chen X, Macdonnell SM, Kranias EG, Lorenz JN, Leitges M, Houser SR, Molkentin JD. Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circulation Research. 105: 194-200. PMID 19556521 DOI: 10.1161/Circresaha.109.195313  0.44
2009 Pritchard TJ, Kranias EG. Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis. The Journal of Physiology. 587: 3125-33. PMID 19403607 DOI: 10.1113/Jphysiol.2009.172171  0.44
2009 Nicolaou P, Rodriguez P, Ren X, Zhou X, Qian J, Sadayappan S, Mitton B, Pathak A, Robbins J, Hajjar RJ, Jones K, Kranias EG. Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circulation Research. 104: 1012-20. PMID 19299645 DOI: 10.1161/Circresaha.108.189811  0.32
2009 Waggoner JR, Ginsburg KS, Mitton B, Haghighi K, Robbins J, Bers DM, Kranias EG. Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport. American Journal of Physiology. Heart and Circulatory Physiology. 296: H698-703. PMID 19112098 DOI: 10.1152/Ajpheart.00272.2008  0.44
2009 Vafiadaki E, Arvanitis DA, Pagakis SN, Papalouka V, Sanoudou D, Kontrogianni-Konstantopoulos A, Kranias EG. The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival. Molecular Biology of the Cell. 20: 306-18. PMID 18971376 DOI: 10.1091/Mbc.E08-06-0587  0.44
2009 Chen G, Zhou X, Pathak A, Dorn GW, Kranias EG. The human G147D-protein phosphatase 1 inhibitor-1 polymorphism is not associated with altered clinical characteristics in heart failure. Cardiology. 112: 224-31. PMID 18698139 DOI: 10.1159/000151240  0.32
2008 Nicolaou P, Knöll R, Haghighi K, Fan GC, Dorn GW, Hasenfub G, Kranias EG. Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects. The Journal of Biological Chemistry. 283: 33465-71. PMID 18790732 DOI: 10.1074/Jbc.M802307200  0.44
2008 Arvanitis DA, Sanoudou D, Kolokathis F, Vafiadaki E, Papalouka V, Kontrogianni-Konstantopoulos A, Theodorakis GN, Paraskevaidis IA, Adamopoulos S, Dorn GW, Kremastinos DT, Kranias EG. The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. European Heart Journal. 29: 2514-25. PMID 18617481 DOI: 10.1093/Eurheartj/Ehn328  0.44
2008 Haghighi K, Chen G, Sato Y, Fan GC, He S, Kolokathis F, Pater L, Paraskevaidis I, Jones WK, Dorn GW, Kremastinos DT, Kranias EG. A human phospholamban promoter polymorphism in dilated cardiomyopathy alters transcriptional regulation by glucocorticoids. Human Mutation. 29: 640-7. PMID 18241046 DOI: 10.1002/Humu.20692  0.36
2008 Chen G, Zhou X, Nicolaou P, Rodriguez P, Song G, Mitton B, Pathak A, Zachariah A, Fan GC, Dorn GW, Kranias EG. A human polymorphism of protein phosphatase-1 inhibitor-1 is associated with attenuated contractile response of cardiomyocytes to beta-adrenergic stimulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1790-6. PMID 18192322 DOI: 10.1096/Fj.07-097428  0.32
2008 Pattison JS, Waggoner JR, James J, Martin L, Gulick J, Osinska H, Klevitsky R, Kranias EG, Robbins J. Phospholamban overexpression in transgenic rabbits. Transgenic Research. 17: 157-70. PMID 17882530 DOI: 10.1007/S11248-007-9139-2  0.44
2007 Kranias EG, Bers DM. Calcium and cardiomyopathies Sub-Cellular Biochemistry. 45: 523-537. PMID 18193651 DOI: 10.1007/978-1-4020-6191-2_20  0.44
2007 Mohler PJ, Healy JA, Xue H, Puca AA, Kline CF, Allingham RR, Kranias EG, Rockman HA, Bennett V. Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. Plos One. 2: e1051. PMID 17940615 DOI: 10.1371/Journal.Pone.0001051  0.44
2007 Arvanitis DA, Vafiadaki E, Fan GC, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1581-9. PMID 17526652 DOI: 10.1152/Ajpheart.00278.2007  0.44
2007 Zhou X, Fan GC, Ren X, Waggoner JR, Gregory KN, Chen G, Jones WK, Kranias EG. Overexpression of histidine-rich Ca-binding protein protects against ischemia/reperfusion-induced cardiac injury. Cardiovascular Research. 75: 487-97. PMID 17499229 DOI: 10.1016/J.Cardiores.2007.04.005  0.44
2007 Pathak A, Baldwin B, Kranias EG. Key protein alterations associated with hyperdynamic cardiac function: insights based on proteomic analysis of the protein phosphatase 1 inhibitor-1 overexpressing hearts. Hellenic Journal of Cardiology : Hjc = HellēNikē Kardiologikē EpitheōRēSĒ. 48: 30-6. PMID 17388107  0.32
2007 Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kranias EG, Kontrogianni-Konstantopoulos A. Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function. Journal of Molecular Biology. 367: 65-79. PMID 17241641 DOI: 10.1016/J.Jmb.2006.10.057  0.44
2007 Yuan Q, Fan GC, Dong M, Altschafl B, Diwan A, Ren X, Hahn HH, Zhao W, Waggoner JR, Jones LR, Jones WK, Bers DM, Dorn GW, Wang HS, Valdivia HH, ... ... Kranias EG, et al. Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity. Circulation. 115: 300-9. PMID 17224479 DOI: 10.1161/Circulationaha.106.654699  0.44
2007 Vila-Petroff M, Salas MA, Said M, Valverde CA, Sapia L, Portiansky E, Hajjar RJ, Kranias EG, Mundiña-Weilenmann C, Mattiazzi A. CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. Cardiovascular Research. 73: 689-98. PMID 17217936 DOI: 10.1016/J.Cardiores.2006.12.003  0.44
2006 Rodriguez P, Mitton B, Waggoner JR, Kranias EG. Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function. The Journal of Biological Chemistry. 281: 38599-608. PMID 17046826 DOI: 10.1074/Jbc.M604139200  0.44
2006 McGraw DW, Fogel KM, Kong S, Litonjua AA, Kranias EG, Aronow BJ, Liggett SB. Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility. Physiological Genomics. 27: 171-7. PMID 16849635 DOI: 10.1152/Physiolgenomics.00044.2006  0.44
2006 Gregory KN, Ginsburg KS, Bodi I, Hahn H, Marreez YM, Song Q, Padmanabhan PA, Mitton BA, Waggoner JR, Del Monte F, Park WJ, Dorn GW, Bers DM, Kranias EG. Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function. Journal of Molecular and Cellular Cardiology. 40: 653-65. PMID 16600288 DOI: 10.1016/J.Yjmcc.2006.02.003  0.44
2006 Valverde CA, Mundiña-Weilenmann C, Reyes M, Kranias EG, Escobar AL, Mattiazzi A. Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart. Cardiovascular Research. 70: 335-45. PMID 16516179 DOI: 10.1016/J.Cardiores.2006.01.018  0.44
2006 Zhao W, Yuan Q, Qian J, Waggoner JR, Pathak A, Chu G, Mitton B, Sun X, Jin J, Braz JC, Hahn HS, Marreez Y, Syed F, Pollesello P, Annila A, ... ... Kranias EG, et al. The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling. Circulation. 113: 995-1004. PMID 16476846 DOI: 10.1161/Circulationaha.105.583351  0.44
2006 Gramolini AO, Trivieri MG, Oudit GY, Kislinger T, Li W, Patel MM, Emili A, Kranias EG, Backx PH, Maclennan DH. Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 103: 2446-51. PMID 16461894 DOI: 10.1073/Pnas.0510883103  0.44
2006 Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, Lynch RA, Fan GC, Tsiapras D, Parekh RR, Dorn GW, MacLennan DH, Kremastinos DT, Kranias EG. A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 103: 1388-93. PMID 16432188 DOI: 10.1073/Pnas.0510519103  0.44
2006 Wu Y, Shintani A, Grueter C, Zhang R, Hou Y, Yang J, Kranias EG, Colbran RJ, Anderson ME. Suppression of dynamic Ca(2+) transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition. Journal of Molecular and Cellular Cardiology. 40: 213-23. PMID 16413575 DOI: 10.1016/J.Yjmcc.2005.11.005  0.44
2006 Ji Y, Zhao W, Li B, Desantiago J, Picht E, Kaetzel MA, Schultz Jel J, Kranias EG, Bers DM, Dedman JR. Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility. American Journal of Physiology. Heart and Circulatory Physiology. 290: H599-606. PMID 16143658 DOI: 10.1152/Ajpheart.00214.2005  0.44
2005 Waggoner JR, Kranias EG. Role of phospholamban in the pathogenesis of heart failure. Heart Failure Clinics. 1: 207-18. PMID 17386847 DOI: 10.1016/J.Hfc.2005.03.008  0.44
2005 Sanoudou D, Vafiadaki E, Arvanitis DA, Kranias E, Kontrogianni-Konstantopoulos A. Array lessons from the heart: focus on the genome and transcriptome of cardiomyopathies. Physiological Genomics. 21: 131-43. PMID 15831843 DOI: 10.1152/Physiolgenomics.00259.2004  0.44
2005 Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Marreez Y, Chen G, ... ... Kranias EG, et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circulation Research. 96: 756-66. PMID 15746443 DOI: 10.1161/01.Res.0000161256.85833.Fa  0.44
2004 Szentesi P, Pignier C, Egger M, Kranias EG, Niggli E. Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle. Circulation Research. 95: 807-13. PMID 15388639 DOI: 10.1161/01.Res.0000146029.80463.7D  0.44
2004 Chu G, Kerr JP, Mitton B, Egnaczyk GF, Vazquez JA, Shen M, Kilby GW, Stevenson TI, Maggio JE, Vockley J, Rapundalo ST, Kranias EG. Proteomic analysis of hyperdynamic mouse hearts with enhanced sarcoplasmic reticulum calcium cycling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1725-7. PMID 15358683 DOI: 10.1096/Fj.04-2025Fje  0.44
2004 Haghighi K, Gregory KN, Kranias EG. Sarcoplasmic reticulum Ca-ATPase-phospholamban interactions and dilated cardiomyopathy. Biochemical and Biophysical Research Communications. 322: 1214-22. PMID 15336969 DOI: 10.1016/J.Bbrc.2004.07.164  0.44
2004 Song Q, Young KB, Chu G, Gulick J, Gerst M, Grupp IL, Robbins J, Kranias EG. Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 974-6. PMID 15059971 DOI: 10.1096/Fj.03-1058Fje  0.36
2004 Pan Y, Kislinger T, Gramolini AO, Zvaritch E, Kranias EG, MacLennan DH, Emili A. Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics. Proceedings of the National Academy of Sciences of the United States of America. 101: 2241-6. PMID 14982994 DOI: 10.1073/Pnas.0308174101  0.44
2004 Engelhardt S, Hein L, Dyachenkow V, Kranias EG, Isenberg G, Lohse MJ. Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation. Circulation. 109: 1154-60. PMID 14967726 DOI: 10.1161/01.Cir.0000117254.68497.39  0.44
2004 Braz JC, Gregory K, Pathak A, Zhao W, Sahin B, Klevitsky R, Kimball TF, Lorenz JN, Nairn AC, Liggett SB, Bodi I, Wang S, Schwartz A, Lakatta EG, DePaoli-Roach AA, ... ... Kranias EG, et al. PKC-alpha regulates cardiac contractility and propensity toward heart failure. Nature Medicine. 10: 248-54. PMID 14966518 DOI: 10.1038/Nm1000  0.44
2004 Gregory KN, Hahn H, Haghighi K, Marreez Y, Odley A, Dorn GW, Kranias EG. Increased particulate partitioning of PKCε reverses susceptibility of phospholamban knockout hearts to ischemic injury Journal of Molecular and Cellular Cardiology. 36: 313-318. PMID 14871559 DOI: 10.1016/J.Yjmcc.2003.12.001  0.44
2004 Chu G, Egnaczyk GF, Zhao W, Jo SH, Fan GC, Maggio JE, Xiao RP, Kranias EG. Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20. Circulation Research. 94: 184-93. PMID 14615292 DOI: 10.1161/01.Res.0000107198.90218.21  0.44
2003 MacLennan DH, Kranias EG. Phospholamban: a crucial regulator of cardiac contractility. Nature Reviews. Molecular Cell Biology. 4: 566-77. PMID 12838339 DOI: 10.1038/Nrm1151  0.44
2003 Schmidt AG, Haghighi K, Frank B, Pater L, Dorn GW, Walsh RA, Kranias EG. Polymorphic SERCA2a variants do not account for inter-individual differences in phospholamban-SERCA2a interactions in human heart failure. Journal of Molecular and Cellular Cardiology. 35: 867-70. PMID 12818578 DOI: 10.1016/S0022-2828(03)00111-1  0.44
2003 Haghighi K, Kolokathis F, Pater L, Lynch RA, Asahi M, Gramolini AO, Fan GC, Tsiapras D, Hahn HS, Adamopoulos S, Liggett SB, Dorn GW, MacLennan DH, Kremastinos DT, Kranias EG. Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human. The Journal of Clinical Investigation. 111: 869-76. PMID 12639993 DOI: 10.1172/Jci17892  0.44
2003 Song Q, Schmidt AG, Hahn HS, Carr AN, Frank B, Pater L, Gerst M, Young K, Hoit BD, McConnell BK, Haghighi K, Seidman CE, Seidman JG, Dorn GW, Kranias EG. Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. The Journal of Clinical Investigation. 111: 859-67. PMID 12639992 DOI: 10.1172/Jci16738  0.76
2003 Brittsan AG, Ginsburg KS, Chu G, Yatani A, Wolska BM, Schmidt AG, Asahi M, MacLennan DH, Bers DM, Kranias EG. Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport. Circulation Research. 92: 769-76. PMID 12637367 DOI: 10.1161/01.Res.0000066661.49920.59  0.44
2003 Dash R, Schmidt AG, Pathak A, Gerst MJ, Biniakiewicz D, Kadambi VJ, Hoit BD, Abraham WT, Kranias EG. Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy. Cardiovascular Research. 57: 704-14. PMID 12618232 DOI: 10.1016/S0008-6363(02)00772-1  0.48
2003 Schmitt JP, Kamisago M, Asahi M, Li GH, Ahmad F, Mende U, Kranias EG, MacLennan DH, Seidman JG, Seidman CE. Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science (New York, N.Y.). 299: 1410-3. PMID 12610310 DOI: 10.1126/Science.1081578  0.44
2003 Isoda T, Paolocci N, Haghighi K, Wang C, Wang Y, Georgakopoulos D, Servillo G, Della Fazia MA, Kranias EG, Depaoli-Roach AA, Sassone-Corsi P, Kass DA. Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 144-51. PMID 12554693 DOI: 10.1096/Fj.01-0981Com  0.44
2003 Zhao W, Frank KF, Chu G, Gerst MJ, Schmidt AG, Ji Y, Periasamy M, Kranias EG. Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state. Cardiovascular Research. 57: 71-81. PMID 12504816 DOI: 10.1016/S0008-6363(02)00609-0  0.48
2002 Chu G, Haghighi K, Kranias EG. From mouse to man: Understanding heart failure through genetically altered mouse models Journal of Cardiac Failure. 8. PMID 12555156 DOI: 10.1054/Jcaf.2002.129284  0.44
2002 Frank KF, Bölck B, Brixius K, Kranias EG, Schwinger RH. Modulation of SERCA: implications for the failing human heart. Basic Research in Cardiology. 97: I72-8. PMID 12479238 DOI: 10.1007/S003950200033  0.44
2002 Schmidt AG, Zhai J, Carr AN, Gerst MJ, Lorenz JN, Pollesello P, Annila A, Hoit BD, Kranias EG. Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure. Cardiovascular Research. 56: 248-59. PMID 12393095 DOI: 10.1016/S0008-6363(02)00541-2  0.76
2002 Schmidt AG, Gerst M, Zhai J, Carr AN, Pater L, Kranias EG, Hoit BD. Evaluation of left ventricular diastolic function from spectral and color M-mode Doppler in genetically altered mice. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 15: 1065-73. PMID 12373248 DOI: 10.1067/Mje.2002.121863  0.76
2002 Carr AN, Kranias EG. Thyroid hormone regulation of calcium cycling proteins. Thyroid : Official Journal of the American Thyroid Association. 12: 453-7. PMID 12165106 DOI: 10.1089/105072502760143818  0.76
2002 Chu G, Carr AN, Young KB, Lester JW, Yatani A, Sanbe A, Colbert MC, Schwartz SM, Frank KF, Lampe PD, Robbins J, Molkentin JD, Kranias EG. Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure. Cardiovascular Research. 54: 105-16. PMID 12062367 DOI: 10.1016/S0008-6363(02)00230-4  0.76
2002 Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, Yatani A, Hoit BD, Grupp IL, Hajjar RJ, DePaoli-Roach AA, ... Kranias EG, et al. Type 1 phosphatase, a negative regulator of cardiac function. Molecular and Cellular Biology. 22: 4124-35. PMID 12024026 DOI: 10.1128/Mcb.22.12.4124-4135.2002  0.44
2002 Wolska BM, Arteaga GM, Peña JR, Nowak G, Phillips RM, Sahai S, de Tombe PP, Martin AF, Kranias EG, Solaro RJ. Expression of slow skeletal troponin I in hearts of phospholamban knockout mice alters the relaxant effect of beta-adrenergic stimulation. Circulation Research. 90: 882-8. PMID 11988489 DOI: 10.1161/01.Res.0000016962.36404.04  0.44
2002 Pi Y, Kemnitz KR, Zhang D, Kranias EG, Walker JW. Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice. Circulation Research. 90: 649-56. PMID 11934831 DOI: 10.1161/01.Res.0000014080.82861.5F  0.44
2002 Li Y, Kranias EG, Mignery GA, Bers DM. Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes. Circulation Research. 90: 309-16. PMID 11861420 DOI: 10.1161/Hh0302.105660  0.44
2002 Kiriazis H, Sato Y, Kadambi VJ, Schmidt AG, Gerst MJ, Hoit BD, Kranias EG. Hypertrophy and functional alterations in hyperdynamic phospholamban-knockout mouse hearts under chronic aortic stenosis. Cardiovascular Research. 53: 372-81. PMID 11827688 DOI: 10.1016/S0008-6363(01)00487-4  0.48
2001 Schmidt AG, Edes I, Kranias EG. Phospholamban: a promising therapeutic target in heart failure? Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 15: 387-96. PMID 11855657 DOI: 10.1023/A:1013381204658  0.48
2001 Frank KF, Mesnard-Rouiller L, Chu G, Young KB, Zhao W, Haghighi K, Sato Y, Kranias EG. Structure and expression of the mouse cardiac calsequestrin gene. Basic Research in Cardiology. 96: 636-44. PMID 11770083 DOI: 10.1007/S003950170016  0.44
2001 Sato Y, Schmidt AG, Kiriazis H, Hoit BD, Kranias EG. Letter to the editor: Re-evaluation of heart failure in transgenic mice with impaired SR Ca2+ release. Journal of Molecular and Cellular Cardiology. 33: 1757-9. PMID 11549354 DOI: 10.1006/Jmcc.2001.1430  0.48
2001 Carr AN, Sutliff RL, Weber CS, Allen PB, Greengard P, de Lanerolle P, Kranias EG, Paul RJ. Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice. The Journal of Physiology. 534: 357-66. PMID 11454956 DOI: 10.1111/J.1469-7793.2001.00357.X  0.76
2001 Dash R, Frank KF, Carr AN, Moravec CS, Kranias EG. Gender influences on sarcoplasmic reticulum Ca2+-handling in failing human myocardium. Journal of Molecular and Cellular Cardiology. 33: 1345-53. PMID 11437540 DOI: 10.1006/Jmcc.2001.1394  0.44
2001 Aronow BJ, Toyokawa T, Canning A, Haghighi K, Delling U, Kranias E, Molkentin JD, Dorn GW. Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy Physiological Genomics. 6: 19-28. PMID 11395543 DOI: 10.1152/Physiolgenomics.2001.6.1.19  0.44
2001 Slack JP, Grupp IL, Dash R, Holder D, Schmidt A, Gerst MJ, Tamura T, Tilgmann C, James PF, Johnson R, Gerdes AM, Kranias EG. The enhanced contractility of the phospholamban-deficient mouse heart persists with aging. Journal of Molecular and Cellular Cardiology. 33: 1031-40. PMID 11343424 DOI: 10.1006/Jmcc.2001.1370  0.44
2001 Haghighi K, Schmidt AG, Hoit BD, Brittsan AG, Yatani A, Lester JW, Zhai J, Kimura Y, Dorn GW, MacLennan DH, Kranias EG. Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure. The Journal of Biological Chemistry. 276: 24145-52. PMID 11328820 DOI: 10.1074/Jbc.M102403200  0.44
2001 Freeman K, Lerman I, Kranias EG, Bohlmeyer T, Bristow MR, Lefkowitz RJ, Iaccarino G, Koch WJ, Leinwand LA. Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy. The Journal of Clinical Investigation. 107: 967-74. PMID 11306600 DOI: 10.1172/Jci12083  0.44
2001 Dash R, Kadambi V, Schmidt AG, Tepe NM, Biniakiewicz D, Gerst MJ, Canning AM, Abraham WT, Hoit BD, Liggett SB, Lorenz JN, Dorn GW, Kranias EG. Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality. Circulation. 103: 889-96. PMID 11171800 DOI: 10.1161/01.Cir.103.6.889  0.48
2001 Sato Y, Kiriazis H, Yatani A, Schmidt AG, Hahn H, Ferguson DG, Sako H, Mitarai S, Honda R, Mesnard-Rouiller L, Frank KF, Beyermann B, Wu G, Fujimori K, Dorn GW, ... Kranias EG, et al. Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation. The Journal of Biological Chemistry. 276: 9392-9. PMID 11115498 DOI: 10.1074/Jbc.M006889200  0.44
2000 Brittsan AG, Kranias EG. Phospholamban and cardiac contractile function. Journal of Molecular and Cellular Cardiology. 32: 2131-9. PMID 11112989 DOI: 10.1006/Jmcc.2000.1270  0.8
2000 Schmidt AG, Kadambi VJ, Ball N, Sato Y, Walsh RA, Kranias EG, Hoit BD. Cardiac-specific overexpression of calsequestrin results in left ventricular hypertrophy, depressed force-frequency relation and pulsus alternans in vivo. Journal of Molecular and Cellular Cardiology. 32: 1735-44. PMID 10966834 DOI: 10.1006/Jmcc.2000.1209  0.48
2000 Zvaritch E, Backx PH, Jirik F, Kimura Y, de Leon S, Schmidt AG, Hoit BD, Lester JW, Kranias EG, MacLennan DH. The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility. The Journal of Biological Chemistry. 275: 14985-91. PMID 10809743 DOI: 10.1074/Jbc.275.20.14985  0.44
2000 Brittsan AG, Carr AN, Schmidt AG, Kranias EG. Maximal inhibition of SERCA2 Ca(2+) affinity by phospholamban in transgenic hearts overexpressing a non-phosphorylatable form of phospholamban. The Journal of Biological Chemistry. 275: 12129-35. PMID 10766848 DOI: 10.1074/Jbc.275.16.12129  0.8
2000 Zhai J, Schmidt AG, Hoit BD, Kimura Y, MacLennan DH, Kranias EG. Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo. The Journal of Biological Chemistry. 275: 10538-44. PMID 10744747 DOI: 10.1074/Jbc.275.14.10538  0.44
2000 Hoit BD, Kadambi VJ, Tramuta DA, Ball N, Kranias EG, Walsh RA. Influence of sarcoplasmic reticulum calcium loading on mechanical and relaxation restitution. American Journal of Physiology. Heart and Circulatory Physiology. 278: H958-63. PMID 10710365 DOI: 10.1152/Ajpheart.2000.278.3.H958  0.36
2000 Hoit BD, Tramuta DA, Kadambi VJ, Dash J, Ball N, Kranias EG, Walsh RA. Erratum: Influence of transgenic overexpression of phospholamban on postextrasystolic potentiation. (Journal of Molecular and Cellular Cardiology (1999) 31 (2007-2015)) Journal of Molecular and Cellular Cardiology. 32: 341-342. DOI: 10.1006/Jmcc.1999.1080  0.36
1999 Kadambi VJ, Ball N, Kranias EG, Walsh RA, Hoit BD. Modulation of force-frequency relation by phospholamban in genetically engineered mice. American Journal of Physiology. Heart and Circulatory Physiology. 276: H2245-H2250. PMID 29592384 DOI: 10.1152/ajpheart.1999.276.6.H2245  0.36
1999 Tepe NM, Lorenz JN, Yatani A, Dash R, Kranias EG, Dorn GW, Liggett SB. Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling. Biochemistry. 38: 16706-13. PMID 10600134 DOI: 10.1021/Bi991619K  0.44
1999 Hoit BD, Tramuta DA, Kadambi VJ, Dash R, Ball N, Kranias EG, Walsh RA. Influence of transgenic overexpression of phospholamban on postextrasystolic potentiation. Journal of Molecular and Cellular Cardiology. 31: 2007-15. PMID 10591027 DOI: 10.1006/Jmcc.1999.1031  0.44
1999 Minamisawa S, Hoshijima M, Chu G, Ward CA, Frank K, Gu Y, Martone ME, Wang Y, Ross J, Kranias EG, Giles WR, Chien KR. Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell. 99: 313-22. PMID 10555147 DOI: 10.1016/S0092-8674(00)81662-1  0.44
1999 Brittsan AG, Kiss E, Edes I, Grupp IL, Grupp G, Kranias EG. The effect of isoproterenol on phospholamban-deficient mouse hearts with altered thyroid conditions. Journal of Molecular and Cellular Cardiology. 31: 1725-37. PMID 10471356 DOI: 10.1006/Jmcc.1999.1010  0.8
1999 Kadambi VJ, Ball N, Kranias EG, Walsh RA, Hoit BD. Modulation of force-frequency relation by phospholamban in genetically engineered mice. The American Journal of Physiology. 276: H2245-50. PMID 10362708 DOI: 10.1152/Ajpheart.1999.276.6.H2245  0.36
1999 Sutliff RL, Hoying JB, Kadambi VJ, Kranias EG, Paul RJ. Phospholamban is present in endothelial cells and modulates endothelium- dependent relaxation evidence from phospholamban gene-ablated mice Circulation Research. 84: 360-364. PMID 10024311 DOI: 10.1161/01.Res.84.3.360  0.44
1998 Kadambi VJ, Kranias EG. Genetically engineered mice: model systems for left ventricular failure. Journal of Cardiac Failure. 4: 349-61. PMID 9924857 DOI: 10.1016/S1071-9164(98)90241-X  0.32
1998 Chu G, Li L, Sato Y, Harrer JM, Kadambi VJ, Hoit BD, Bers DM, Kranias EG. Pentameric assembly of phospholamban facilitates inhibition of cardiac function in vivo. The Journal of Biological Chemistry. 273: 33674-80. PMID 9837953 DOI: 10.1074/Jbc.273.50.33674  0.36
1998 Sato Y, Ferguson DG, Sako H, Dorn GW, Kadambi VJ, Yatani A, Hoit BD, Walsh RA, Kranias EG. Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice. The Journal of Biological Chemistry. 273: 28470-7. PMID 9774476 DOI: 10.1074/Jbc.273.43.28470  0.36
1998 Kiss E, Brittsan AG, Edes I, Grupp IL, Grupp G, Kranias EG. Thyroid hormone-induced alterations in phospholamban-deficient mouse hearts. Circulation Research. 83: 608-13. PMID 9742056 DOI: 10.1161/01.Res.83.6.608  0.8
1998 Kadambi VJ, Koss KL, Grupp IL, Kranias EG. Phospholamban modulates murine atrial contractile parameters and responses to beta-adrenergic agonists. Journal of Molecular and Cellular Cardiology. 30: 1275-84. PMID 9710796 DOI: 10.1006/Jmcc.1998.0688  0.32
1998 Masaki H, Sako H, Kadambi VJ, Sato Y, Kranias EG, Yatani A. Overexpression of phospholamban alters inactivation kinetics of L-type Ca2+ channel currents in mouse atrial myocytes. Journal of Molecular and Cellular Cardiology. 30: 317-25. PMID 9515008 DOI: 10.1006/Jmcc.1997.0594  0.32
1998 Luo W, Chu G, Sato Y, Zhou Z, Kadambi VJ, Kranias EG. Transgenic approaches to define the functional role of dual site phospholamban phosphorylation. The Journal of Biological Chemistry. 273: 4734-9. PMID 9468536 DOI: 10.1074/Jbc.273.8.4734  0.32
1998 Zhou M, Sutliff RL, Paul RJ, Lorenz JN, Hoying JB, Haudenschild CC, Yin M, Coffin JD, Kong L, Kranias EG, Luo W, Boivin GP, Duffy JJ, Pawlowski SA, Doetschman T. Fibroblast growth factor 2 control of vascular tone. Nature Medicine. 4: 201-7. PMID 9461194 DOI: 10.1038/Nm0298-201  0.44
1997 Haghighi K, Kadambi VJ, Koss KL, Luo W, Harrer JM, Ponniah S, Zhou Z, Kranias EG. In vitro and in vivo promoter analyses of the mouse phospholamban gene Gene. 203: 199-207. PMID 9426251 DOI: 10.1016/S0378-1119(97)00514-3  0.44
1997 Sako H, Green SA, Kranias EG, Yatani A. Modulation of cardiac Ca2+ channels by isoproterenol studied in transgenic mice with altered SR Ca2+ content American Journal of Physiology - Cell Physiology. 273. PMID 9374653 DOI: 10.1152/Ajpcell.1997.273.5.C1666  0.44
1997 Santana LF, Kranias EG, Lederer WJ. Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. The Journal of Physiology. 503: 21-9. PMID 9288671 DOI: 10.1111/J.1469-7793.1997.021Bi.X  0.44
1996 Chu G, Luo W, Slack JP, Tilgmann C, Sweet WE, Spindler M, Saupe KW, Boivin GP, Moravec CS, Matlib MA, Grupp IL, Ingwall JS, Kranias EG. Compensatory mechanisms associated with the hyperdynamic function of phospholamban-deficient mouse hearts. Circulation Research. 79: 1064-76. PMID 8943945 DOI: 10.1161/01.Res.79.6.1064  0.44
1996 Wolska BM, Stojanovic MO, Luo W, Kranias EG, Solaro RJ. Effect of ablation of phospholamban on dynamics of cardiac myocyte contraction and intracellular Ca2+ American Journal of Physiology - Cell Physiology. 271. PMID 8760070 DOI: 10.1152/Ajpcell.1996.271.1.C391  0.44
1996 Kadambi VJ, Ponniah S, Harrer JM, Hoit BD, Dorn GW, Walsh RA, Kranias EG. Cardiac-specific overexpression of phospholamban alters calcium kinetics and resultant cardiomyocyte mechanics in transgenic mice. The Journal of Clinical Investigation. 97: 533-9. PMID 8567978 DOI: 10.1172/Jci118446  0.36
1995 Hoit BD, Khoury SF, Kranias EG, Ball N, Walsh RA. In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency. Circulation Research. 77: 632-7. PMID 7641333 DOI: 10.1161/01.Res.77.3.632  0.36
1995 Kiss E, Ball NA, Kranias EG, Walsh RA. Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca2+-ATPase protein levels: Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure Circulation Research. 77: 759-764. PMID 7554123 DOI: 10.1161/01.Res.77.4.759  0.44
1993 Hardin CD, Zhang C, Kranias EG, Steenaart NAE, Raeymaekers L, Paul RJ. Regulation of glycolytically fueled Ca2+ uptake in smooth muscle plasmalemmal vesicles by phosphorylation American Journal of Physiology - Heart and Circulatory Physiology. 265. PMID 8238421 DOI: 10.1152/Ajpheart.1993.265.4.H1326  0.44
1989 Edes I, Solaro RJ, Kranias EG. Changes in phosphoinositide turnover in isolated guinea pig hearts stimulated with isoproterenol Circulation Research. 65: 989-996. PMID 2551534 DOI: 10.1161/01.Res.65.4.989  0.44
1989 Rapundalo ST, Solaro RJ, Kranias EG. Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: Comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins Circulation Research. 64: 104-111. PMID 2535795 DOI: 10.1161/01.Res.64.1.104  0.44
1988 Jakab G, Rapundalo ST, Solaro RJ, Kranias EG. Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline Biochemical Journal. 251: 189-194. PMID 3390153 DOI: 10.1042/Bj2510189  0.44
1988 Garvey JL, Kranias EG, Solaro RJ. Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts Biochemical Journal. 249: 709-714. PMID 2895634 DOI: 10.1042/Bj2490709  0.44
1985 Kranias EG, Garvey JL, Srivastava RD, Solaro RJ. Phosphorylation and functional modifications of sarcoplasmic reticulum and myofibrils in isolated rabbit hearts stimulated with isoprenaline Biochemical Journal. 226: 113-121. PMID 3156585 DOI: 10.1042/Bj2260113  0.44
1982 Kranias EG, Solaro RJ. Phosphorylation of troponin I and phospholamban during catecholamine stimulation of rabbit heart Nature. 298: 182-184. PMID 6211626 DOI: 10.1038/298182A0  0.44
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