Evangelia G. Kranias - Publications

University of Cincinnati, Cincinnati, OH 
Pharmacology, Molecular Biology, Animal Physiology Biology

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lam CK, Zhao W, Liu GS, Cai WF, Gardner G, Adly G, Kranias EG. HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart. Proceedings of the National Academy of Sciences of the United States of America. PMID 26553996 DOI: 10.1073/pnas.1508760112  0.44
2015 Haghighi K, Pritchard TJ, Liu GS, Singh VP, Bidwell P, Lam CK, Vafiadaki E, Das P, Ma J, Kunduri S, Sanoudou D, Florea S, Vanderbilt E, Wang HS, Rubinstein J, ... ... Kranias EG, et al. Human G109E-inhibitor-1 impairs cardiac function and promotes arrhythmias. Journal of Molecular and Cellular Cardiology. PMID 26455482 DOI: 10.1016/j.yjmcc.2015.10.004  0.44
2015 Cai WF, Liu GS, Lam CK, Florea S, Qian J, Zhao W, Pritchard T, Haghighi K, Lebeche D, Lu LJ, Deng J, Fan GC, Hajjar RJ, Kranias EG. Up-regulation of micro-RNA765 in human failing hearts is associated with post-transcriptional regulation of protein phosphatase inhibitor-1 and depressed contractility. European Journal of Heart Failure. 17: 782-93. PMID 26177627 DOI: 10.1002/ejhf.323  0.44
2015 Karakikes I, Stillitano F, Nonnenmacher M, Tzimas C, Sanoudou D, Termglinchan V, Kong CW, Rushing S, Hansen J, Ceholski D, Kolokathis F, Kremastinos D, Katoulis A, Ren L, Cohen N, ... ... Kranias EG, et al. Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy. Nature Communications. 6: 6955. PMID 25923014 DOI: 10.1038/ncomms7955  0.44
2015 Liu GS, Morales A, Vafiadaki E, Lam CK, Cai WF, Haghighi K, Adly G, Hershberger RE, Kranias EG. A novel human R25C-phospholamban mutation is associated with super-inhibition of calcium cycling and ventricular arrhythmia. Cardiovascular Research. 107: 164-74. PMID 25852082 DOI: 10.1093/cvr/cvv127  0.44
2014 Haghighi K, Bidwell P, Kranias EG. Phospholamban interactome in cardiac contractility and survival: A new vision of an old friend. Journal of Molecular and Cellular Cardiology. 77: 160-7. PMID 25451386 DOI: 10.1016/j.yjmcc.2014.10.005  0.44
2014 Ishikawa K, Fish KM, Tilemann L, Rapti K, Aguero J, Santos-Gallego CG, Lee A, Karakikes I, Xie C, Akar FG, Shimada YJ, Gwathmey JK, Asokan A, McPhee S, Samulski J, ... ... Kranias EG, et al. Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2038-45. PMID 25023328 DOI: 10.1038/mt.2014.127  0.44
2014 Vafiadaki E, Arvanitis DA, Papalouka V, Terzis G, Roumeliotis TI, Spengos K, Garbis SD, Manta P, Kranias EG, Sanoudou D. Muscle lim protein isoform negatively regulates striated muscle actin dynamics and differentiation. The Febs Journal. 281: 3261-79. PMID 24860983 DOI: 10.1111/febs.12859  0.44
2014 Rubinstein J, Lasko VM, Koch SE, Singh VP, Carreira V, Robbins N, Patel AR, Jiang M, Bidwell P, Kranias EG, Jones WK, Lorenz JN. Novel role of transient receptor potential vanilloid 2 in the regulation of cardiac performance. American Journal of Physiology. Heart and Circulatory Physiology. 306: H574-84. PMID 24322617 DOI: 10.1152/ajpheart.00854.2013  0.44
2013 Pritchard TJ, Kawase Y, Haghighi K, Anjak A, Cai W, Jiang M, Nicolaou P, Pylar G, Karakikes I, Rapti K, Rubinstein J, Hajjar RJ, Kranias EG. Active inhibitor-1 maintains protein hyper-phosphorylation in aging hearts and halts remodeling in failing hearts. Plos One. 8: e80717. PMID 24312496 DOI: 10.1371/journal.pone.0080717  0.44
2013 Singh VP, Rubinstein J, Arvanitis DA, Ren X, Gao X, Haghighi K, Gilbert M, Iyer VR, Kim do H, Cho C, Jones K, Lorenz JN, Armstrong CF, Wang HS, Gyorke S, ... Kranias EG, et al. Abnormal calcium cycling and cardiac arrhythmias associated with the human Ser96Ala genetic variant of histidine-rich calcium-binding protein. Journal of the American Heart Association. 2: e000460. PMID 24125847 DOI: 10.1161/JAHA.113.000460  0.44
2013 Sivakumaran V, Stanley BA, Tocchetti CG, Ballin JD, Caceres V, Zhou L, Keceli G, Rainer PP, Lee DI, Huke S, Ziolo MT, Kranias EG, Toscano JP, Wilson GM, O'Rourke B, et al. HNO enhances SERCA2a activity and cardiomyocyte function by promoting redox-dependent phospholamban oligomerization. Antioxidants & Redox Signaling. 19: 1185-97. PMID 23919584 DOI: 10.1089/ars.2012.5057  0.44
2013 Park CS, Chen S, Lee H, Cha H, Oh JG, Hong S, Han P, Ginsburg KS, Jin S, Park I, Singh VP, Wang HS, Franzini-Armstrong C, Park WJ, Bers DM, ... Kranias EG, et al. Targeted ablation of the histidine-rich Ca(2+)-binding protein (HRC) gene is associated with abnormal SR Ca(2+)-cycling and severe pathology under pressure-overload stress. Basic Research in Cardiology. 108: 344. PMID 23553082 DOI: 10.1007/s00395-013-0344-2  0.44
2013 Fish KM, Ladage D, Kawase Y, Karakikes I, Jeong D, Ly H, Ishikawa K, Hadri L, Tilemann L, Muller-Ehmsen J, Samulski RJ, Kranias EG, Hajjar RJ. AAV9.I-1c delivered via direct coronary infusion in a porcine model of heart failure improves contractility and mitigates adverse remodeling. Circulation. Heart Failure. 6: 310-7. PMID 23271792 DOI: 10.1161/CIRCHEARTFAILURE.112.971325  0.44
2013 Lam CK, Zhao W, Cai W, Vafiadaki E, Florea SM, Ren X, Liu Y, Robbins N, Zhang Z, Zhou X, Jiang M, Rubinstein J, Jones WK, Kranias EG. Novel role of HAX-1 in ischemic injury protection involvement of heat shock protein 90. Circulation Research. 112: 79-89. PMID 22982986 DOI: 10.1161/CIRCRESAHA.112.279935  0.44
2012 Park CS, Cha H, Kwon EJ, Jeong D, Hajjar RJ, Kranias EG, Cho C, Park WJ, Kim DH. AAV-Mediated Knock-Down of HRC Exacerbates Transverse Aorta Constriction-Induced Heart Failure Plos One. 7. PMID 22952658 DOI: 10.1371/journal.pone.0043282  0.44
2012 Florea S, Anjak A, Cai WF, Qian J, Vafiadaki E, Figueria S, Haghighi K, Rubinstein J, Lorenz J, Kranias EG. Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging. Basic Research in Cardiology. 107: 279. PMID 22777184 DOI: 10.1007/s00395-012-0279-z  0.44
2012 Boncompagni S, Thomas M, Lopez JR, Allen PD, Yuan Q, Kranias EG, Franzini-Armstrong C, Perez CF. Triadin/Junctin double null mouse reveals a differential role for Triadin and Junctin in anchoring CASQ to the jSR and regulating Ca(2+) homeostasis. Plos One. 7: e39962. PMID 22768324 DOI: 10.1371/journal.pone.0039962  0.44
2012 Cai WF, Pritchard T, Florea S, Lam CK, Han P, Zhou X, Yuan Q, Lehnart SE, Allen PD, Kranias EG. Ablation of junctin or triadin is associated with increased cardiac injury following ischaemia/reperfusion. Cardiovascular Research. 94: 333-41. PMID 22411973 DOI: 10.1093/cvr/cvs119  0.44
2012 Haghighi K, Pritchard T, Bossuyt J, Waggoner JR, Yuan Q, Fan GC, Osinska H, Anjak A, Rubinstein J, Robbins J, Bers DM, Kranias EG. The human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPase. Journal of Molecular and Cellular Cardiology. 52: 773-82. PMID 22155237 DOI: 10.1016/j.yjmcc.2011.11.012  0.44
2012 Sassi Y, Abi-Gerges A, Fauconnier J, Mougenot N, Reiken S, Haghighi K, Kranias EG, Marks AR, Lacampagne A, Engelhardt S, Hatem SN, Lompre AM, Hulot JS. Regulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 1009-17. PMID 22090316 DOI: 10.1096/fj.11-194027  0.44
2011 Altschafl BA, Arvanitis DA, Fuentes O, Yuan Q, Kranias EG, Valdivia HH. Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes. The Journal of Physiology. 589: 6063-80. PMID 22025663 DOI: 10.1113/jphysiol.2011.215988  0.44
2011 Gaffin RD, Peña JR, Alves MS, Dias FA, Chowdhury SA, Heinrich LS, Goldspink PH, Kranias EG, Wieczorek DF, Wolska BM. Long-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein. Journal of Molecular and Cellular Cardiology. 51: 812-20. PMID 21840315 DOI: 10.1016/j.yjmcc.2011.07.026  0.44
2011 Han P, Cai W, Wang Y, Lam CK, Arvanitis DA, Singh VP, Chen S, Zhang H, Zhang R, Cheng H, Kranias EG. Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1588-95. PMID 21742996 DOI: 10.1152/ajpheart.01153.2010  0.44
2011 Qian J, Vafiadaki E, Florea SM, Singh VP, Song W, Lam CK, Wang Y, Yuan Q, Pritchard TJ, Cai W, Haghighi K, Rodriguez P, Wang HS, Sanoudou D, Fan GC, ... Kranias EG, et al. Small heat shock protein 20 interacts with protein phosphatase-1 and enhances sarcoplasmic reticulum calcium cycling. Circulation Research. 108: 1429-38. PMID 21493896 DOI: 10.1161/CIRCRESAHA.110.237644  0.44
2011 Goonasekera SA, Lam CK, Millay DP, Sargent MA, Hajjar RJ, Kranias EG, Molkentin JD. Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. The Journal of Clinical Investigation. 121: 1044-52. PMID 21285509 DOI: 10.1172/JCI43844  0.44
2011 Wang HS, Arvanitis DA, Dong M, Niklewski PJ, Zhao W, Lam CK, Kranias EG, Sanoudou D. SERCA2a superinhibition by human phospholamban triggers electrical and structural remodeling in mouse hearts. Physiological Genomics. 43: 357-64. PMID 21266500 DOI: 10.1152/physiolgenomics.00032.2010  0.44
2010 Hadri L, Bobe R, Kawase Y, Ladage D, Ishikawa K, Atassi F, Lebeche D, Kranias EG, Leopold JA, Lompré AM, Lipskaia L, Hajjar RJ. SERCA2a gene transfer enhances eNOS expression and activity in endothelial cells Molecular Therapy. 18: 1284-1292. PMID 20461063 DOI: 10.1038/mt.2010.77  0.44
2010 Lompré AM, Hajjar RJ, Harding SE, Kranias EG, Lohse MJ, Marks AR. Ca2+ cycling and new therapeutic approaches for heart failure. Circulation. 121: 822-30. PMID 20124124 DOI: 10.1161/CIRCULATIONAHA.109.890954  0.44
2010 Salas MA, Valverde CA, Sánchez G, Said M, Rodriguez JS, Portiansky EL, Kaetzel MA, Dedman JR, Donoso P, Kranias EG, Mattiazzi A. The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury. Journal of Molecular and Cellular Cardiology. 48: 1298-306. PMID 20060004 DOI: 10.1016/j.yjmcc.2009.12.015  0.44
2010 Zhang T, Guo T, Mishra S, Dalton ND, Kranias EG, Peterson KL, Bers DM, Brown JH. Phospholamban ablation rescues sarcoplasmic reticulum Ca(2+) handling but exacerbates cardiac dysfunction in CaMKIIdelta(C) transgenic mice. Circulation Research. 106: 354-62. PMID 19959778 DOI: 10.1161/CIRCRESAHA.109.207423  0.44
2009 Zhao W, Waggoner JR, Zhang ZG, Lam CK, Han P, Qian J, Schroder PM, Mitton B, Kontrogianni-Konstantopoulos A, Robia SL, Kranias EG. The anti-apoptotic protein HAX-1 is a regulator of cardiac function. Proceedings of the National Academy of Sciences of the United States of America. 106: 20776-81. PMID 19920172 DOI: 10.1073/pnas.0906998106  0.44
2009 Liu Q, Chen X, Macdonnell SM, Kranias EG, Lorenz JN, Leitges M, Houser SR, Molkentin JD. Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. Circulation Research. 105: 194-200. PMID 19556521 DOI: 10.1161/CIRCRESAHA.109.195313  0.44
2009 Pritchard TJ, Kranias EG. Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis. The Journal of Physiology. 587: 3125-33. PMID 19403607 DOI: 10.1113/jphysiol.2009.172171  0.44
2009 Nicolaou P, Rodriguez P, Ren X, Zhou X, Qian J, Sadayappan S, Mitton B, Pathak A, Robbins J, Hajjar RJ, Jones K, Kranias EG. Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury. Circulation Research. 104: 1012-20. PMID 19299645 DOI: 10.1161/CIRCRESAHA.108.189811  0.32
2009 Waggoner JR, Ginsburg KS, Mitton B, Haghighi K, Robbins J, Bers DM, Kranias EG. Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport. American Journal of Physiology. Heart and Circulatory Physiology. 296: H698-703. PMID 19112098 DOI: 10.1152/ajpheart.00272.2008  0.44
2009 Vafiadaki E, Arvanitis DA, Pagakis SN, Papalouka V, Sanoudou D, Kontrogianni-Konstantopoulos A, Kranias EG. The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival. Molecular Biology of the Cell. 20: 306-18. PMID 18971376 DOI: 10.1091/mbc.E08-06-0587  0.44
2009 Chen G, Zhou X, Pathak A, Dorn GW, Kranias EG. The human G147D-protein phosphatase 1 inhibitor-1 polymorphism is not associated with altered clinical characteristics in heart failure. Cardiology. 112: 224-31. PMID 18698139 DOI: 10.1159/000151240  0.32
2008 Nicolaou P, Knöll R, Haghighi K, Fan GC, Dorn GW, Hasenfub G, Kranias EG. Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects. The Journal of Biological Chemistry. 283: 33465-71. PMID 18790732 DOI: 10.1074/jbc.M802307200  0.44
2008 Arvanitis DA, Sanoudou D, Kolokathis F, Vafiadaki E, Papalouka V, Kontrogianni-Konstantopoulos A, Theodorakis GN, Paraskevaidis IA, Adamopoulos S, Dorn GW, Kremastinos DT, Kranias EG. The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy. European Heart Journal. 29: 2514-25. PMID 18617481 DOI: 10.1093/eurheartj/ehn328  0.44
2008 Haghighi K, Chen G, Sato Y, Fan GC, He S, Kolokathis F, Pater L, Paraskevaidis I, Jones WK, Dorn GW, Kremastinos DT, Kranias EG. A human phospholamban promoter polymorphism in dilated cardiomyopathy alters transcriptional regulation by glucocorticoids. Human Mutation. 29: 640-7. PMID 18241046 DOI: 10.1002/humu.20692  0.36
2008 Chen G, Zhou X, Nicolaou P, Rodriguez P, Song G, Mitton B, Pathak A, Zachariah A, Fan GC, Dorn GW, Kranias EG. A human polymorphism of protein phosphatase-1 inhibitor-1 is associated with attenuated contractile response of cardiomyocytes to beta-adrenergic stimulation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 1790-6. PMID 18192322 DOI: 10.1096/fj.07-097428  0.32
2008 Pattison JS, Waggoner JR, James J, Martin L, Gulick J, Osinska H, Klevitsky R, Kranias EG, Robbins J. Phospholamban overexpression in transgenic rabbits. Transgenic Research. 17: 157-70. PMID 17882530 DOI: 10.1007/s11248-007-9139-2  0.44
2007 Mohler PJ, Healy JA, Xue H, Puca AA, Kline CF, Allingham RR, Kranias EG, Rockman HA, Bennett V. Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence. Plos One. 2: e1051. PMID 17940615 DOI: 10.1371/journal.pone.0001051  0.44
2007 Arvanitis DA, Vafiadaki E, Fan GC, Mitton BA, Gregory KN, Del Monte F, Kontrogianni-Konstantopoulos A, Sanoudou D, Kranias EG. Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase. American Journal of Physiology. Heart and Circulatory Physiology. 293: H1581-9. PMID 17526652 DOI: 10.1152/ajpheart.00278.2007  0.44
2007 Zhou X, Fan GC, Ren X, Waggoner JR, Gregory KN, Chen G, Jones WK, Kranias EG. Overexpression of histidine-rich Ca-binding protein protects against ischemia/reperfusion-induced cardiac injury. Cardiovascular Research. 75: 487-97. PMID 17499229 DOI: 10.1016/j.cardiores.2007.04.005  0.44
2007 Pathak A, Baldwin B, Kranias EG. Key protein alterations associated with hyperdynamic cardiac function: insights based on proteomic analysis of the protein phosphatase 1 inhibitor-1 overexpressing hearts. Hellenic Journal of Cardiology : Hjc = HellēNikē Kardiologikē EpitheōRēSĒ. 48: 30-6. PMID 17388107  0.32
2007 Vafiadaki E, Sanoudou D, Arvanitis DA, Catino DH, Kranias EG, Kontrogianni-Konstantopoulos A. Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function. Journal of Molecular Biology. 367: 65-79. PMID 17241641 DOI: 10.1016/j.jmb.2006.10.057  0.44
2007 Yuan Q, Fan GC, Dong M, Altschafl B, Diwan A, Ren X, Hahn HH, Zhao W, Waggoner JR, Jones LR, Jones WK, Bers DM, Dorn GW, Wang HS, Valdivia HH, ... ... Kranias EG, et al. Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity. Circulation. 115: 300-9. PMID 17224479 DOI: 10.1161/CIRCULATIONAHA.106.654699  0.44
2007 Vila-Petroff M, Salas MA, Said M, Valverde CA, Sapia L, Portiansky E, Hajjar RJ, Kranias EG, Mundiña-Weilenmann C, Mattiazzi A. CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury. Cardiovascular Research. 73: 689-98. PMID 17217936 DOI: 10.1016/j.cardiores.2006.12.003  0.44
2006 Rodriguez P, Mitton B, Waggoner JR, Kranias EG. Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function. The Journal of Biological Chemistry. 281: 38599-608. PMID 17046826 DOI: 10.1074/jbc.M604139200  0.44
2006 McGraw DW, Fogel KM, Kong S, Litonjua AA, Kranias EG, Aronow BJ, Liggett SB. Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility. Physiological Genomics. 27: 171-7. PMID 16849635 DOI: 10.1152/physiolgenomics.00044.2006  0.44
2006 Gregory KN, Ginsburg KS, Bodi I, Hahn H, Marreez YM, Song Q, Padmanabhan PA, Mitton BA, Waggoner JR, Del Monte F, Park WJ, Dorn GW, Bers DM, Kranias EG. Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function. Journal of Molecular and Cellular Cardiology. 40: 653-65. PMID 16600288 DOI: 10.1016/j.yjmcc.2006.02.003  0.44
2006 Valverde CA, Mundiña-Weilenmann C, Reyes M, Kranias EG, Escobar AL, Mattiazzi A. Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart. Cardiovascular Research. 70: 335-45. PMID 16516179 DOI: 10.1016/j.cardiores.2006.01.018  0.44
2006 Zhao W, Yuan Q, Qian J, Waggoner JR, Pathak A, Chu G, Mitton B, Sun X, Jin J, Braz JC, Hahn HS, Marreez Y, Syed F, Pollesello P, Annila A, ... ... Kranias EG, et al. The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling. Circulation. 113: 995-1004. PMID 16476846 DOI: 10.1161/CIRCULATIONAHA.105.583351  0.44
2006 Gramolini AO, Trivieri MG, Oudit GY, Kislinger T, Li W, Patel MM, Emili A, Kranias EG, Backx PH, Maclennan DH. Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 103: 2446-51. PMID 16461894 DOI: 10.1073/pnas.0510883103  0.44
2006 Haghighi K, Kolokathis F, Gramolini AO, Waggoner JR, Pater L, Lynch RA, Fan GC, Tsiapras D, Parekh RR, Dorn GW, MacLennan DH, Kremastinos DT, Kranias EG. A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 103: 1388-93. PMID 16432188 DOI: 10.1073/pnas.0510519103  0.44
2006 Wu Y, Shintani A, Grueter C, Zhang R, Hou Y, Yang J, Kranias EG, Colbran RJ, Anderson ME. Suppression of dynamic Ca(2+) transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition. Journal of Molecular and Cellular Cardiology. 40: 213-23. PMID 16413575 DOI: 10.1016/j.yjmcc.2005.11.005  0.44
2006 Ji Y, Zhao W, Li B, Desantiago J, Picht E, Kaetzel MA, Schultz Jel J, Kranias EG, Bers DM, Dedman JR. Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility. American Journal of Physiology. Heart and Circulatory Physiology. 290: H599-606. PMID 16143658 DOI: 10.1152/ajpheart.00214.2005  0.44
2005 Waggoner JR, Kranias EG. Role of phospholamban in the pathogenesis of heart failure. Heart Failure Clinics. 1: 207-18. PMID 17386847 DOI: 10.1016/j.hfc.2005.03.008  0.44
2005 Pathak A, del Monte F, Zhao W, Schultz JE, Lorenz JN, Bodi I, Weiser D, Hahn H, Carr AN, Syed F, Mavila N, Jha L, Qian J, Marreez Y, Chen G, ... ... Kranias EG, et al. Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1. Circulation Research. 96: 756-66. PMID 15746443 DOI: 10.1161/01.RES.0000161256.85833.fa  0.44
2004 Szentesi P, Pignier C, Egger M, Kranias EG, Niggli E. Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle. Circulation Research. 95: 807-13. PMID 15388639 DOI: 10.1161/01.RES.0000146029.80463.7d  0.44
2004 Chu G, Kerr JP, Mitton B, Egnaczyk GF, Vazquez JA, Shen M, Kilby GW, Stevenson TI, Maggio JE, Vockley J, Rapundalo ST, Kranias EG. Proteomic analysis of hyperdynamic mouse hearts with enhanced sarcoplasmic reticulum calcium cycling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1725-7. PMID 15358683 DOI: 10.1096/fj.04-2025fje  0.44
2004 Haghighi K, Gregory KN, Kranias EG. Sarcoplasmic reticulum Ca-ATPase-phospholamban interactions and dilated cardiomyopathy. Biochemical and Biophysical Research Communications. 322: 1214-22. PMID 15336969 DOI: 10.1016/j.bbrc.2004.07.164  0.44
2004 Song Q, Young KB, Chu G, Gulick J, Gerst M, Grupp IL, Robbins J, Kranias EG. Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 974-6. PMID 15059971 DOI: 10.1096/fj.03-1058fje  0.36
2003 Song Q, Schmidt AG, Hahn HS, Carr AN, Frank B, Pater L, Gerst M, Young K, Hoit BD, McConnell BK, Haghighi K, Seidman CE, Seidman JG, Dorn GW, Kranias EG. Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy. The Journal of Clinical Investigation. 111: 859-67. PMID 12639992 DOI: 10.1172/JCI16738  0.76
2003 Brittsan AG, Ginsburg KS, Chu G, Yatani A, Wolska BM, Schmidt AG, Asahi M, MacLennan DH, Bers DM, Kranias EG. Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport. Circulation Research. 92: 769-76. PMID 12637367 DOI: 10.1161/01.RES.0000066661.49920.59  0.44
2003 Dash R, Schmidt AG, Pathak A, Gerst MJ, Biniakiewicz D, Kadambi VJ, Hoit BD, Abraham WT, Kranias EG. Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy. Cardiovascular Research. 57: 704-14. PMID 12618232  0.48
2002 Schmidt AG, Zhai J, Carr AN, Gerst MJ, Lorenz JN, Pollesello P, Annila A, Hoit BD, Kranias EG. Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure. Cardiovascular Research. 56: 248-59. PMID 12393095  0.76
2002 Schmidt AG, Gerst M, Zhai J, Carr AN, Pater L, Kranias EG, Hoit BD. Evaluation of left ventricular diastolic function from spectral and color M-mode Doppler in genetically altered mice. Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography. 15: 1065-73. PMID 12373248  0.76
2002 Carr AN, Kranias EG. Thyroid hormone regulation of calcium cycling proteins. Thyroid : Official Journal of the American Thyroid Association. 12: 453-7. PMID 12165106 DOI: 10.1089/105072502760143818  0.76
2002 Chu G, Carr AN, Young KB, Lester JW, Yatani A, Sanbe A, Colbert MC, Schwartz SM, Frank KF, Lampe PD, Robbins J, Molkentin JD, Kranias EG. Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure. Cardiovascular Research. 54: 105-16. PMID 12062367  0.76
2002 Carr AN, Schmidt AG, Suzuki Y, del Monte F, Sato Y, Lanner C, Breeden K, Jing SL, Allen PB, Greengard P, Yatani A, Hoit BD, Grupp IL, Hajjar RJ, DePaoli-Roach AA, ... Kranias EG, et al. Type 1 phosphatase, a negative regulator of cardiac function. Molecular and Cellular Biology. 22: 4124-35. PMID 12024026 DOI: 10.1128/MCB.22.12.4124-4135.2002  0.44
2001 Carr AN, Sutliff RL, Weber CS, Allen PB, Greengard P, de Lanerolle P, Kranias EG, Paul RJ. Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice. The Journal of Physiology. 534: 357-66. PMID 11454956  0.76
2001 Dash R, Frank KF, Carr AN, Moravec CS, Kranias EG. Gender influences on sarcoplasmic reticulum Ca2+-handling in failing human myocardium. Journal of Molecular and Cellular Cardiology. 33: 1345-53. PMID 11437540 DOI: 10.1006/jmcc.2001.1394  0.44
2001 Slack JP, Grupp IL, Dash R, Holder D, Schmidt A, Gerst MJ, Tamura T, Tilgmann C, James PF, Johnson R, Gerdes AM, Kranias EG. The enhanced contractility of the phospholamban-deficient mouse heart persists with aging. Journal of Molecular and Cellular Cardiology. 33: 1031-40. PMID 11343424 DOI: 10.1006/jmcc.2001.1370  0.44
2001 Haghighi K, Schmidt AG, Hoit BD, Brittsan AG, Yatani A, Lester JW, Zhai J, Kimura Y, Dorn GW, MacLennan DH, Kranias EG. Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure. The Journal of Biological Chemistry. 276: 24145-52. PMID 11328820 DOI: 10.1074/jbc.M102403200  0.44
2001 Dash R, Kadambi V, Schmidt AG, Tepe NM, Biniakiewicz D, Gerst MJ, Canning AM, Abraham WT, Hoit BD, Liggett SB, Lorenz JN, Dorn GW, Kranias EG. Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality. Circulation. 103: 889-96. PMID 11171800  0.48
2000 Brittsan AG, Kranias EG. Phospholamban and cardiac contractile function. Journal of Molecular and Cellular Cardiology. 32: 2131-9. PMID 11112989 DOI: 10.1006/jmcc.2000.1270  0.8
2000 Brittsan AG, Carr AN, Schmidt AG, Kranias EG. Maximal inhibition of SERCA2 Ca(2+) affinity by phospholamban in transgenic hearts overexpressing a non-phosphorylatable form of phospholamban. The Journal of Biological Chemistry. 275: 12129-35. PMID 10766848  0.8
1999 Kadambi VJ, Ball N, Kranias EG, Walsh RA, Hoit BD. Modulation of force-frequency relation by phospholamban in genetically engineered mice. American Journal of Physiology. Heart and Circulatory Physiology. 276: H2245-H2250. PMID 29592384 DOI: 10.1152/ajpheart.1999.276.6.H2245  0.36
1999 Tepe NM, Lorenz JN, Yatani A, Dash R, Kranias EG, Dorn GW, Liggett SB. Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling. Biochemistry. 38: 16706-13. PMID 10600134  0.44
1999 Hoit BD, Tramuta DA, Kadambi VJ, Dash R, Ball N, Kranias EG, Walsh RA. Influence of transgenic overexpression of phospholamban on postextrasystolic potentiation. Journal of Molecular and Cellular Cardiology. 31: 2007-15. PMID 10591027 DOI: 10.1006/jmcc.1999.1031  0.44
1999 Brittsan AG, Kiss E, Edes I, Grupp IL, Grupp G, Kranias EG. The effect of isoproterenol on phospholamban-deficient mouse hearts with altered thyroid conditions. Journal of Molecular and Cellular Cardiology. 31: 1725-37. PMID 10471356 DOI: 10.1006/jmcc.1999.1010  0.8
1998 Kiss E, Brittsan AG, Edes I, Grupp IL, Grupp G, Kranias EG. Thyroid hormone-induced alterations in phospholamban-deficient mouse hearts. Circulation Research. 83: 608-13. PMID 9742056  0.8
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