Justin A. Spanier, Ph.D. - Related publications

Affiliations: 
2011 University of Wisconsin, Madison, Madison, WI 
Area:
Immunology
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50 most relevant papers in past 60 days:
Year Citation  Score
2019 Zhao P, Wang P, Dong S, Zhou Z, Cao Y, Yagita H, He X, Zheng SG, Fisher SJ, Fujinami RS, Chen M. Depletion of PD-1-positive cells ameliorates autoimmune disease. Nature Biomedical Engineering. 3: 292-305. PMID 30952980 DOI: 10.1038/s41551-019-0360-0   
2019 Wei SC, Sharma R, Anang NAS, Levine JH, Zhao Y, Mancuso JJ, Setty M, Sharma P, Wang J, Pe'er D, Allison JP. Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States. Immunity. PMID 30926234 DOI: 10.1016/j.immuni.2019.03.004   
2019 Visekruna A, Hartmann S, Sillke YR, Glauben R, Fischer F, Raifer H, Mollenkopf H, Bertrams W, Schmeck B, Klein M, Pagenstecher A, Lohoff M, Jacob R, Pabst O, Bland PW, et al. Intestinal development and homeostasis require activation and apoptosis of diet-reactive T cells. The Journal of Clinical Investigation. 130. PMID 30939122 DOI: 10.1172/JCI98929   
2019 Rosenberg KM, Singh NJ. Mouse T cells express a neurotransmitter-receptor signature that is quantitatively modulated in a subset and activation dependent manner. Brain, Behavior, and Immunity. PMID 30953766 DOI: 10.1016/j.bbi.2019.04.002   
2019 Sungnak W, Wang C, Kuchroo VK. Multilayer regulation of CD4 T cell subset differentiation in the era of single cell genomics. Advances in Immunology. 141: 1-31. PMID 30904130 DOI: 10.1016/bs.ai.2018.12.001   
2019 Acevedo GR, Alcaráz PB, Pinilla C, Gómez KA. Generation of T. cruzi-Specific Primary CD4 T Cell Lines from Peripheral Blood Mononuclear Cells Isolated from Chagas Disease Patients. Methods in Molecular Biology (Clifton, N.J.). 1955: 315-337. PMID 30868538 DOI: 10.1007/978-1-4939-9148-8_24   
2019 Gu L, Cui X, Lang S, Wang H, Hong T, Wei R. Glucagon receptor antagonism increases mouse pancreatic δ-cell mass through cell proliferation and duct-derived neogenesis. Biochemical and Biophysical Research Communications. PMID 30929915 DOI: 10.1016/j.bbrc.2019.03.148   
2019 Dhaeze T, Lachance C, Tremblay L, Grasmuck C, Bourbonnière L, Larouche S, Saint-Laurent O, Lécuyer MA, Rébillard RM, Zandee S, Prat A. Sex-dependent factors encoded in the immune compartment dictate relapsing or progressive phenotype in demyelinating disease. Jci Insight. 4. PMID 30895941 DOI: 10.1172/jci.insight.124885   
2019 Huang H, Sikora MJ, Islam S, Chowdhury RR, Chien YH, Scriba TJ, Davis MM, Steinmetz LM. Select sequencing of clonally expanded CD8 T cells reveals limits to clonal expansion. Proceedings of the National Academy of Sciences of the United States of America. PMID 30992377 DOI: 10.1073/pnas.1902649116   
2019 Ayasoufi K, Zwick DB, Fan R, Hasgur S, Nicosia M, Gorbacheva V, Keslar KS, Min B, Fairchild RL, Valujskikh A. Interleukin-27 promotes CD8+ T cell reconstitution following antibody-mediated lymphoablation. Jci Insight. 4. PMID 30944247 DOI: 10.1172/jci.insight.125489   
2019 Wang T, Sun G, Wang Y, Li S, Zhao X, Zhang C, Jin H, Tian D, Liu K, Shi W, Tian Y, Zhang D. The immunoregulatory effects of CD8 T-cell-derived perforin on diet-induced nonalcoholic steatohepatitis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802534RR. PMID 30951375 DOI: 10.1096/fj.201802534RR   
2019 Saul L, Mair I, Ivens A, Brown P, Samuel K, Campbell JDM, Soong DY, Kamenjarin N, Mellanby RJ. 1,25-Dihydroxyvitamin D Restrains CD4 T Cell Priming Ability of CD11c Dendritic Cells by Upregulating Expression of CD31. Frontiers in Immunology. 10: 600. PMID 30984180 DOI: 10.3389/fimmu.2019.00600   
2019 Zhang W, Okimura T, Oda T, Jin JO. Ascophyllan Induces Activation of Natural Killer Cells in Mice In Vivo and In Vitro. Marine Drugs. 17. PMID 30925723 DOI: 10.3390/md17040197   
2019 Sidles SJ, Xiong Y, Young MRI, LaRue AC. High-Fat Diet Alters Immunogenic Properties of Circulating and Adipose Tissue-Associated Myeloid-Derived CD45DDR2 Cells. Mediators of Inflammation. 2019: 1648614. PMID 31015794 DOI: 10.1155/2019/1648614   
2019 Sidles SJ, Xiong Y, Young MRI, LaRue AC. High-Fat Diet Alters Immunogenic Properties of Circulating and Adipose Tissue-Associated Myeloid-Derived CD45DDR2 Cells. Mediators of Inflammation. 2019: 1648614. PMID 31015794 DOI: 10.1155/2019/1648614   
2019 Zhang R, Deng Q, Jiang YY, Zhu HB, Wang J, Zhao MF. Effect and changes in PD‑1 expression of CD19 CAR‑T cells from T cells highly expressing PD‑1 combined with reduced‑dose PD‑1 inhibitor. Oncology Reports. PMID 30942469 DOI: 10.3892/or.2019.7096   
2019 MacNabb BW, Kline DE, Albright AR, Chen X, Leventhal DS, Savage PA, Kline J. Negligible Role for Deletion Mediated by cDC1 in CD8 T Cell Tolerance. Journal of Immunology (Baltimore, Md. : 1950). PMID 30902900 DOI: 10.4049/jimmunol.1801621   
2019 Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR. Hypoxia-inducible factors in CD4 T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30988188 DOI: 10.1073/pnas.1811702116   
2019 Edholm EI, De Jesús Andino F, Yim J, Woo K, Robert J. Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection. Viruses. 11. PMID 30959883 DOI: 10.3390/v11040330   
2019 Agrawal S, Khokhar A, Gupta S. Cytomegalovirus Colitis in Primary Hypogammaglobulinemia With Normal CD4+ T Cells: Deficiency of CMV-Specific CD8+ T Cells. Frontiers in Immunology. 10: 399. PMID 30899266 DOI: 10.3389/fimmu.2019.00399   
2019 Ma WT, Chen DK. Immunological abnormalities in patients with primary biliary cholangitis. Clinical Science (London, England : 1979). 133: 741-760. PMID 30890652 DOI: 10.1042/CS20181123   
2019 Chiou HC, Lin MW, Hsiao PJ, Chen CL, Chiao S, Lin TY, Chen YC, Wu DC, Lin MH. Dulaglutide Modulates the Development of Tissue-Infiltrating Th1/Th17 Cells and the Pathogenicity of Encephalitogenic Th1 Cells in the Central Nervous System. International Journal of Molecular Sciences. 20. PMID 30934882 DOI: 10.3390/ijms20071584   
2019 Zhang X, Wang P, Chen T, Yan W, Guan X, Shen G, Luo X, Wan X, Ning Q. Kctd9 Deficiency Impairs Natural Killer Cell Development and Effector Function. Frontiers in Immunology. 10: 744. PMID 31024568 DOI: 10.3389/fimmu.2019.00744   
2019 Fribourg M, Anderson L, Fischman C, Cantarelli C, Perin L, La Manna G, Rahman A, Burrell BE, Heeger PS, Cravedi P. T-cell exhaustion correlates with improved outcomes in kidney transplant recipients. Kidney International. PMID 31040060 DOI: 10.1016/j.kint.2019.01.040   
2019 Becerra-Artiles A, Cruz J, Leszyk JD, Sidney J, Sette A, Shaffer SA, Stern LJ. Naturally processed HLA-DR3-restricted HHV-6b peptides are recognized broadly with polyfunctional and cytotoxic CD4 T cell responses. European Journal of Immunology. PMID 31020640 DOI: 10.1002/eji.201948126   
2019 Matsuo T, Hashimoto M, Sakaguchi S, Sakaguchi N, Ito Y, Hikida M, Tsuruyama T, Sakai K, Yokoi H, Shirakashi M, Tanaka M, Ito H, Yoshifuji H, Ohmura K, Fujii T, et al. Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Mutation. Journal of Immunology (Baltimore, Md. : 1950). PMID 31019063 DOI: 10.4049/jimmunol.1801159   
2019 Kim DH, Park HJ, Park HS, Lee JU, Ko C, Gye MC, Choi JM. Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity. Experimental & Molecular Medicine. 51: 41. PMID 30988419 DOI: 10.1038/s12276-019-0237-z   
2019 Yang M, Liu Y, Mo B, Xue Y, Ye C, Jiang Y, Bi X, Liu M, Wu Y, Wang J, Olsen N, Pan Y, Zheng SG. Helios but not CD226, TIGIT and Foxp3 is a Potential Marker for CD4 Treg Cells in Patients with Rheumatoid Arthritis. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 52: 1178-1192. PMID 30990587 DOI: 10.33594/000000080   
2019 Patel S, Burga RA, Powell AB, Chorvinsky EA, Hoq N, McCormack SE, Van Pelt SN, Hanley PJ, Cruz CRY. Beyond CAR T Cells: Other Cell-Based Immunotherapeutic Strategies Against Cancer. Frontiers in Oncology. 9: 196. PMID 31024832 DOI: 10.3389/fonc.2019.00196   
2019 Previte DM, Martins CP, O'Connor EC, Marre ML, Coudriet GM, Beck NW, Menk AV, Wright RH, Tse HM, Delgoffe GM, Piganelli JD. Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4 T Cells. Cell Reports. 27: 129-141.e4. PMID 30943396 DOI: 10.1016/j.celrep.2019.03.004   
2019 Turner JE, Rickassel C, Healy H, Kassianos AJ. Natural Killer Cells in Kidney Health and Disease. Frontiers in Immunology. 10: 587. PMID 30972076 DOI: 10.3389/fimmu.2019.00587   
2019 Helble JD, Starnbach MN. A strain expressing OVA stimulates an antigen-specific CD4 T cell response in mice. Infection and Immunity. PMID 30988057 DOI: 10.1128/IAI.00837-18   
2019 Meryk A, Pangrazzi L, Hagen M, Hatzmann F, Jenewein B, Jakic B, Hermann-Kleiter N, Baier G, Jylhävä J, Hurme M, Trieb K, Grubeck-Loebenstein B. Fcμ receptor as a Costimulatory Molecule for T Cells. Cell Reports. 26: 2681-2691.e5. PMID 30840890 DOI: 10.1016/j.celrep.2019.02.024   
2019 Xia Y, Zhang Z, Li S, Zhan Q, Xiao Q, Wang L, Liu L, Luo X. [Culture and expansion of CMV-specific T cells derived from peripheral blood stem cells in vitro]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. 35: 63-73. PMID 30914116   
2019 Sng J, Ayoglu B, Chen JW, Schickel JN, Ferre EMN, Glauzy S, Romberg N, Hoenig M, Cunningham-Rundles C, Utz PJ, Lionakis MS, Meffre E. AIRE expression controls the peripheral selection of autoreactive B cells. Science Immunology. 4. PMID 30979797 DOI: 10.1126/sciimmunol.aav6778   
2019 Martinov T, Fife BT. Type 1 diabetes pathogenesis and the role of inhibitory receptors in islet tolerance. Annals of the New York Academy of Sciences. PMID 31025378 DOI: 10.1111/nyas.14106   
2019 Secinaro MA, Fortner KA, Collins C, Rincón M, Budd RC. Glycolysis Induces MCJ Expression That Links T Cell Proliferation With Caspase-3 Activity and Death. Frontiers in Cell and Developmental Biology. 7: 28. PMID 30915331 DOI: 10.3389/fcell.2019.00028   
2019 Lee HR, Baek KH. Role of natural killer cells for immunotherapy in chronic myeloid leukemia (Review). Oncology Reports. PMID 30896812 DOI: 10.3892/or.2019.7059   
2019 Verma NK, Kelleher D. An Introduction to LFA-1/ICAM-1 Interactions in T-Cell Motility. Methods in Molecular Biology (Clifton, N.J.). 1930: 1-9. PMID 30610592 DOI: 10.1007/978-1-4939-9036-8_1   
2019 Costanza M, Poliani PL, Portararo P, Cappetti B, Musio S, Pagani F, Steinman L, Colombo MP, Pedotti R, Sangaletti S. DNA threads released by activated CD4 T lymphocytes provide autocrine costimulation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30988194 DOI: 10.1073/pnas.1822013116   
2019 Hirasaki M, Mizuno Y, Ida Y, Murakoshi T, Okuda A, Kotani N. Identification and characterization of splenic adherent cells forming densely-packed colonies. Development, Growth & Differentiation. PMID 30919971 DOI: 10.1111/dgd.12605   
2019 Masse-Ranson G, Dusséaux M, Fiquet O, Darche S, Boussand M, Li Y, Lopez-Lastra S, Legrand N, Corcuff E, Toubert A, Centlivre M, Bruel T, Spits H, Schwartz O, Lévy Y, et al. Accelerated thymopoiesis and improved T cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice. European Journal of Immunology. PMID 30888052 DOI: 10.1002/eji.201848001   
2019 Wagner AK, Alici E, Lowdell MW. Characterization of human natural killer cells for therapeutic use. Cytotherapy. PMID 30910383 DOI: 10.1016/j.jcyt.2018.11.001   
2019 Wang Z, Vaughan TY, Zhu W, Chen Y, Fu G, Medrzycki M, Nishio H, Bunting ST, Hankey-Giblin PA, Nusrat A, Parkos CA, Wang D, Wen R, Bunting KD. Gab2 and Gab3 Redundantly Suppress Colitis by Modulating Macrophage and CD8 T-Cell Activation. Frontiers in Immunology. 10: 486. PMID 30936879 DOI: 10.3389/fimmu.2019.00486   
2019 Mizuno R, Sugiura D, Shimizu K, Maruhashi T, Watada M, Okazaki IM, Okazaki T. PD-1 Primarily Targets TCR Signal in the Inhibition of Functional T Cell Activation. Frontiers in Immunology. 10: 630. PMID 31001256 DOI: 10.3389/fimmu.2019.00630   
2019 Gu W, Ni Z, Tan YQ, Deng J, Zhang SJ, Lv ZC, Wang XJ, Chen T, Zhang Z, Hu Y, Jing ZC, Xu Q. Adventitial Cell Atlas of wt (Wild Type) and ApoE (Apolipoprotein E)-Deficient Mice Defined by Single-Cell RNA Sequencing. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA119312399. PMID 30943771 DOI: 10.1161/ATVBAHA.119.312399   
2019 Hayes AJ, Rane S, Scales HE, Meehan GR, Benson RA, Maroof A, Schroeder J, Tomura M, Gozzard N, Yates AJ, Garside P, Brewer JM. Spatiotemporal Modeling of the Key Migratory Events During the Initiation of Adaptive Immunity. Frontiers in Immunology. 10: 598. PMID 31024523 DOI: 10.3389/fimmu.2019.00598   
2019 Barta SK, Zain J, MacFarlane AW, Smith SM, Ruan J, Fung HC, Tan CR, Yang Y, Alpaugh RK, Dulaimi E, Ross EA, Campbell KS, Khan N, Siddharta R, Fowler NH, et al. Phase II Study of the PD-1 Inhibitor Pembrolizumab for the Treatment of Relapsed or Refractory Mature T-cell Lymphoma. Clinical Lymphoma, Myeloma & Leukemia. PMID 31029646 DOI: 10.1016/j.clml.2019.03.022   
2019 Anderson CK, Reilly EC, Lee AY, Brossay L. Qa-1-Restricted CD8 T Cells Can Compensate for the Absence of Conventional T Cells during Viral Infection. Cell Reports. 27: 537-548.e5. PMID 30970256 DOI: 10.1016/j.celrep.2019.03.059   
2019 Zhuang X, Long EO. CD28 homolog is a strong activator of natural killer cells for lysis of B7H7+ tumor cells. Cancer Immunology Research. PMID 31018957 DOI: 10.1158/2326-6066.CIR-18-0733