| Year |
Citation |
Score |
| 2023 |
Saha K, Subramenium Ganapathy A, Wang A, Arumugam P, Michael Morris N, Harris L, Yochum G, Koltun W, Perdew GH, Nighot M, Ma T, Nighot P. Alpha-tocopherylquinone-mediated activation of the Aryl Hydrocarbon Receptor regulates the production of inflammation-inducing cytokines and ameliorates intestinal inflammation. Mucosal Immunology. PMID 37716509 DOI: 10.1016/j.mucimm.2023.09.003 |
0.703 |
|
| 2023 |
Ganapathy AS, Saha K, Wang A, Arumugam P, Dharmaprakash V, Yochum G, Koltun W, Nighot M, Perdew G, Thompson TA, Ma T, Nighot P. Alpha-tocopherylquinone differentially modulates claudins to enhance intestinal epithelial tight junction barrier via AhR and Nrf2 pathways. Cell Reports. 42: 112705. PMID 37393618 DOI: 10.1016/j.celrep.2023.112705 |
0.768 |
|
| 2022 |
Nighot M, Liao PL, Morris N, Mccarthy D, Dharmaprakash V, Khan IU, Dalessio S, Saha K, Ganapathy AS, Wang A, Ding W, Yochum G, Koltun W, Nighot P, Ma T. Long term use of Proton Pump Inhibitor disrupts intestinal tight junction barrier and exaggerates experimental colitis. Journal of Crohn's & Colitis. PMID 36322638 DOI: 10.1093/ecco-jcc/jjac168 |
0.737 |
|
| 2022 |
Saha K, Ganapathy AS, Wang A, Morris NM, Suchanec E, Ding W, Yochum G, Koltun W, Nighot M, Ma T, Nighot P. Autophagy Reduces the Degradation and Promotes Membrane Localization of Occludin to Enhance the Intestinal Epithelial Tight Junction Barrier against Paracellular Macromolecule Flux. Journal of Crohn's & Colitis. PMID 36219473 DOI: 10.1093/ecco-jcc/jjac148 |
0.753 |
|
| 2021 |
Ganapathy AS, Saha K, Suchanec E, Singh V, Verma A, Yochum G, Koltun W, Nighot M, Ma T, Nighot P. AP2M1 mediates autophagy-induced CLDN2 (claudin 2) degradation through endocytosis and interaction with LC3 and reduces intestinal epithelial tight junction permeability. Autophagy. 1-18. PMID 34964704 DOI: 10.1080/15548627.2021.2016233 |
0.743 |
|
| 2021 |
Al-Sadi R, Dharmaprakash V, Nighot P, Guo S, Nighot M, Do T, Ma TY. Enhances the Intestinal Epithelial Tight Junction Barrier and Protects against Intestinal Inflammation by Targeting the Toll-like Receptor-2 Pathway in an NF-κB-Independent Manner. International Journal of Molecular Sciences. 22. PMID 34360835 DOI: 10.3390/ijms22158070 |
0.776 |
|
| 2021 |
Nighot M, Ganapathy AS, Saha K, Suchanec E, Castillo E, Gregory A, Shapiro S, Ma T, Nighot P. Matrix Metalloproteinase MMP-12 promotes macrophage transmigration across intestinal epithelial tight junctions and increases severity of experimental colitis. Journal of Crohn's & Colitis. PMID 33836047 DOI: 10.1093/ecco-jcc/jjab064 |
0.703 |
|
| 2021 |
Al-Sadi R, Nighot P, Nighot M, Haque M, Rawat M, Ma TY. Lactobacillus acidophilus induces a strain-specific and toll-like receptor-2 dependent enhancement of intestinal epithelial tight junction barrier and protection against intestinal inflammation. The American Journal of Pathology. PMID 33607043 DOI: 10.1016/j.ajpath.2021.02.003 |
0.756 |
|
| 2020 |
Nighot P, Ma T. Endocytosis of Intestinal Tight Junction Proteins: In Time and Space. Inflammatory Bowel Diseases. PMID 32497180 DOI: 10.1093/ibd/izaa141 |
0.302 |
|
| 2020 |
Singh V, Gowda CP, Singh V, Ganapathy AS, Karamchandani DM, Eshelman MA, Yochum GS, Nighot P, Spiegelman VS. The mRNA-binding protein IGF2BP1 maintains intestinal barrier function by up-regulating Occludin expression. The Journal of Biological Chemistry. PMID 32385106 DOI: 10.1074/Jbc.Ac120.013646 |
0.451 |
|
| 2020 |
Ganapathy AS, Suchanec E, Saha K, Nighot M, Ma TY, Nighot PK. Su1104 ALPHA-TOCOPHERYLQUINONE ACTIVATES ARYL HYDROCARBON RECEPTOR AND ENHANCES INTESTINAL EPITHELIAL TIGHT JUNCTION BARRIER FUNCTION Gastroenterology. 158: S-510. DOI: 10.1016/S0016-5085(20)31956-9 |
0.729 |
|
| 2020 |
Priyamvada S, Jayawardena D, Anbazhagan AN, Kumar A, Saksena S, Gill RK, Borthakur A, Nighot P, Alrefai WA, Dudeja PK. Sa1086 AUTOPHAGY REGULATES PUTATIVE ANION TRANSPORTER 1 EXPRESSION IN INTESTINAL EPITHELIAL CELLS Gastroenterology. 158: S-271. DOI: 10.1016/S0016-5085(20)31361-5 |
0.435 |
|
| 2019 |
Wong M, Ganapathy AS, Suchanec E, Laidler L, Ma T, Nighot PK. Intestinal Epithelial Tight Junction Barrier regulation by Autophagy related protein ATG6/beclin 1. American Journal of Physiology. Cell Physiology. PMID 30892937 DOI: 10.1152/ajpcell.00246.2018 |
0.399 |
|
| 2019 |
Nighot M, Rawat M, Sadi RA, Castillo EF, Nighot P, Ma T. Lipopolysaccharide-Induced Increase in Intestinal Permeability Is Mediated by TAK-1 Activation of IKK and MLCK/MYLK Gene. The American Journal of Pathology. PMID 30711488 DOI: 10.1016/j.ajpath.2018.12.016 |
0.732 |
|
| 2019 |
Al-Sadi R, Nighot P, Nighot M, Guo S, Ma TY. P123 LACTOBACILLUS ACIDOPHILUS MODULATION OF MOUSE INTESTINAL TIGHT JUNCTION BARRIER: ROLE OF TOLL-LIKE RECEPTOR-2 (TLR-2) Gastroenterology. 156: S86. DOI: 10.1053/J.Gastro.2019.01.199 |
0.735 |
|
| 2019 |
Al-Sadi R, Nighot P, Nighot M, Guo S, Ma TY. Su1829 – Lactobacillus Acidophilus Causes an Enhancement of Intestinal Epithelial Tight Junction Barrier and Protects Against Dss-Induced Colitis Gastroenterology. 156: S-627. DOI: 10.1016/S0016-5085(19)38466-5 |
0.777 |
|
| 2019 |
Ganapathy AS, Suchanec E, Nighot PK. 986 – Alpha-Tocopherylquinone Enhances Intestinal Epithelial Tight Junction Barrier by Differential Modulation of Claudins Expression Gastroenterology. 156: S-209-S-210. DOI: 10.1016/S0016-5085(19)37318-4 |
0.398 |
|
| 2019 |
Nighot MP, Castillo EF, Rawat M, Dokladny K, Al-Sadi R, Nighot P, Ma TY. 697 – Intestinal Permeability is an Important Factor in the Development of Alcoholic Liver Disease in a Chronic and Binge Mouse Model of Alcoholic Steatohepatitis Gastroenterology. 156: S-152-S-153. DOI: 10.1016/S0016-5085(19)37171-9 |
0.671 |
|
| 2018 |
Nighot M, Nighot P. Pathophysiology of avian intestinal ion transport. World's Poultry Science Journal. 74: 347-360. PMID 29805185 DOI: 10.1017/S004393391800003X |
0.75 |
|
| 2018 |
Nighot PK, Borunda T, Laidler L, Wong M, Thompson T, Oprea T, Sklar L, Ma TY. 264 - Tocopherylquinone-Mediated Activation of Aryl Hydrocarbon Receptor Reduces Intestinal Epithelial Tight Junction Permeability and Severity of Experimental Colitis Gastroenterology. 154: S-65. DOI: 10.1016/S0016-5085(18)30671-1 |
0.447 |
|
| 2017 |
Nighot M, Al-Sadi R, Guo S, Rawat M, Nighot P, Watterson MD, Ma TY. Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase Expression. The American Journal of Pathology. 187: 2698-2710. PMID 29157665 DOI: 10.1016/J.Ajpath.2017.08.005 |
0.759 |
|
| 2017 |
Nighot PK, Leung L, Ma TY. Chloride channel ClC- 2 enhances intestinal epithelial tight junction barrier function via regulation of caveolin-1 and caveolar trafficking of occludin. Experimental Cell Research. PMID 28161538 DOI: 10.1016/J.Yexcr.2017.01.024 |
0.462 |
|
| 2017 |
Wong M, Leung L, Nighot PK. Role of Autophagy Related Protein ATG6/Beclin 1 in Intestinal Tight Junction Barrier Gastroenterology. 152: S119. DOI: 10.1016/S0016-5085(17)30734-5 |
0.427 |
|
| 2016 |
Meliopoulos VA, Marvin SA, Freiden P, Moser LA, Nighot P, Ali R, Blikslager A, Reddivari M, Heath RJ, Koci MD, Schultz-Cherry S. Oral Administration of Astrovirus Capsid Protein Is Sufficient To Induce Acute Diarrhea In Vivo. Mbio. 7. PMID 27803180 DOI: 10.1128/Mbio.01494-16 |
0.634 |
|
| 2016 |
Moore SA, Nighot P, Reyes C, Rawat M, McKee J, Lemon D, Hanson J, Ma TY. Intestinal barrier dysfunction in human necrotizing enterocolitis. Journal of Pediatric Surgery. PMID 27720222 DOI: 10.1016/J.Jpedsurg.2016.09.011 |
0.423 |
|
| 2016 |
Nighot P, Ma T. Role of autophagy in the regulation of epithelial cell junctions. Tissue Barriers. 4: e1171284. PMID 27583189 DOI: 10.1080/21688370.2016.1171284 |
0.362 |
|
| 2016 |
Al-Sadi R, Nighot P, Guo S, Al-Omari D, Ma TY. Tu2019 Lactobacillus Acidophilus Enhancement of Intestinal Epithelial Tight Junction Barrier Is Mediated by p38 Kinase and Toll-Like Receptor-2 (TLR-2) Gastroenterology. 150: S1007. DOI: 10.1016/S0016-5085(16)33411-4 |
0.429 |
|
| 2016 |
Nighot PK, Leung L, Ma TY. 375 Chloride Channel ClC- 2 Enhances Tight Junction Barrier Function in Intestinal Epithelial Cells via Regulation of Caveolin-1 and Caveolar Trafficking of Occludin Gastroenterology. 150: S84. DOI: 10.1016/S0016-5085(16)30400-0 |
0.485 |
|
| 2015 |
Nighot PK, Al-Sadi R, Rawat M, Guo S, Watterson DM, Ma TY. Matrix Metalloproteinase 9-induced increase in intestinal epithelial tight junction permeability contributes to the severity of experimental DSS colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00256.2015. PMID 26514773 DOI: 10.1152/Ajpgi.00256.2015 |
0.457 |
|
| 2015 |
Guo S, Nighot M, Al-Sadi R, Alhmoud T, Nighot P, Ma TY. Lipopolysaccharide Regulation of Intestinal Tight Junction Permeability Is Mediated by TLR4 Signal Transduction Pathway Activation of FAK and MyD88. Journal of Immunology (Baltimore, Md. : 1950). PMID 26466961 DOI: 10.4049/Jimmunol.1402598 |
0.75 |
|
| 2015 |
Nighot MP, Nighot PK, Ma TY, Malinowska DH, Shull GE, Cuppoletti J, Blikslager AT. Genetic Ablation of the ClC-2 Cl- Channel Disrupts Mouse Gastric Parietal Cell Acid Secretion. Plos One. 10: e0138174. PMID 26378782 DOI: 10.1371/Journal.Pone.0138174 |
0.747 |
|
| 2015 |
Nighot PK, Hu CA, Ma TY. Autophagy enhances intestinal epithelial tight junction barrier function by targeting claudin-2 protein degradation. The Journal of Biological Chemistry. 290: 7234-46. PMID 25616664 DOI: 10.1074/Jbc.M114.597492 |
0.502 |
|
| 2015 |
Al-Sadi R, Nighot PK, Ma TY. Su1902 MMP-12 Modulation of Intestinal Epithelial Tight Junction Barrier Is Mediated by P38 Kinase Activation of Myosin Light Chain Kianse (MLCK) Gastroenterology. 148: S-548. DOI: 10.1016/S0016-5085(15)31838-2 |
0.38 |
|
| 2015 |
Nighot PK, Ma TY. 513 Matrix Metalloproteinase MMP-12 Increases Intestinal Epithelial Tight Junction Permeability and Severity of Experimental Colitis Gastroenterology. 148: S-101. DOI: 10.1016/S0016-5085(15)30345-0 |
0.427 |
|
| 2014 |
Nighot MP, Nighot PK, Ma TY, Blikslager A. Su1947 Genetic Absence of Chloride Channel CLC-2 Results in Disruption of Organization and Function of Murine Gastric Glands Gastroenterology. 146: S-505-S-506. DOI: 10.1016/S0016-5085(14)61827-8 |
0.741 |
|
| 2014 |
Nighot PK, Guo S, Rawat M, Hu CA, Ma TY. Su1865 Mechanism of Autophagy Regulation of Intestinal Epithelial TJ Barrier: Role of Claudin-2 in TJ Barrier Enhancement Gastroenterology. 146: S-489. DOI: 10.1016/S0016-5085(14)61755-8 |
0.302 |
|
| 2014 |
Guo S, Al-Sadi R, Nighot PK, Alhmoud T, Ma TY. 75 Lipopolysaccharide Induced Increase in Intestinal Tight Junction Permeability Is Regulated by FAK Dependent Activation of MYD88 Signaling Pathway Gastroenterology. 146: S-21. DOI: 10.1016/S0016-5085(14)60075-5 |
0.416 |
|
| 2013 |
Nighot P, Young K, Nighot M, Rawat M, Sung EJ, Maharshak N, Plevy SE, Ma T, Blikslager A. Chloride channel ClC-2 is a key factor in the development of DSS-induced murine colitis. Inflammatory Bowel Diseases. 19: 2867-77. PMID 24030525 DOI: 10.1097/Mib.0B013E3182A82Ae9 |
0.787 |
|
| 2013 |
Nighot MP, Nighot PK, Young K, Edwards L, Blikslager A, Moeser AJ. Tu1641 Effects of Lubiprostone in a Porcine Model of Stress-Induced Intestinal Barrier Injury Gastroenterology. 144: S-812-S-813. DOI: 10.1016/S0016-5085(13)63010-3 |
0.77 |
|
| 2013 |
Nighot PK, Guo S, Al-Sadi R, Youssef MA, Ma TY. 179 Matrix Metalloproteinase MMP-9-Induced Increase in Intestinal Epithelial Tight Junction Permeability Contributes to the Severity of Experimental DSS Colitis Gastroenterology. 144: S-43. DOI: 10.1016/S0016-5085(13)60150-X |
0.376 |
|
| 2012 |
Cuppoletti J, Blikslager AT, Chakrabarti J, Nighot PK, Malinowska DH. Contrasting effects of linaclotide and lubiprostone on restitution of epithelial cell barrier properties and cellular homeostasis after exposure to cell stressors. Bmc Pharmacology. 12: 3. PMID 22553939 DOI: 10.1186/1471-2210-12-3 |
0.597 |
|
| 2012 |
Meyerhoff RR, Nighot PK, Ali RA, Blikslager AT, Koci MD. Characterization of turkey inducible nitric oxide synthase and identification of its expression in the intestinal epithelium following astrovirus infection. Comparative Immunology, Microbiology and Infectious Diseases. 35: 63-9. PMID 22118854 DOI: 10.1016/J.Cimid.2011.10.002 |
0.594 |
|
| 2012 |
Nighot PK, Blikslager AT. Chloride channel ClC-2 modulates tight junction barrier function via intracellular trafficking of occludin. American Journal of Physiology. Cell Physiology. 302: C178-87. PMID 21956164 DOI: 10.1152/Ajpcell.00072.2011 |
0.611 |
|
| 2012 |
Nighot PK, Young K, Blikslager A. 211 Chloride Channel CLC-2 Mediated Tight Junction Barrier Function Modulates DSS-Induced Murine Colitis Gastroenterology. 142: S-52. DOI: 10.1016/S0016-5085(12)60200-5 |
0.62 |
|
| 2011 |
Nighot PK, Blikslager A. The Chloride Channel CLC-2 Modulates Tight Junction Barrier Function via Intracellular Trafficking Gastroenterology. 140: S-503. DOI: 10.1016/S0016-5085(11)62083-0 |
0.581 |
|
| 2011 |
Nighot PK, Young K, Blikslager A. Chloride Channel CLC-2 Modulates Susceptibility to DSS-Induced Murine Colitis: Implications for the Role of the Tight Junction in IBD Gastroenterology. 140: S-502. DOI: 10.1016/S0016-5085(11)62079-9 |
0.602 |
|
| 2011 |
Nighot MP, Blikslager A, Nighot PK. The Chloride Channel CLC-2 is Involved in Organization of Murine Gastric Glands Gastroenterology. 140: S-93. DOI: 10.1016/S0016-5085(11)60379-X |
0.758 |
|
| 2010 |
Kajino-Sakamoto R, Omori E, Nighot PK, Blikslager AT, Matsumoto K, Ninomiya-Tsuji J. TGF-beta-activated kinase 1 signaling maintains intestinal integrity by preventing accumulation of reactive oxygen species in the intestinal epithelium. Journal of Immunology (Baltimore, Md. : 1950). 185: 4729-37. PMID 20855879 DOI: 10.4049/Jimmunol.0903587 |
0.651 |
|
| 2010 |
Nighot PK, Blikslager AT. ClC-2 regulates mucosal barrier function associated with structural changes to the villus and epithelial tight junction. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G449-56. PMID 20489043 DOI: 10.1152/Ajpgi.00520.2009 |
0.673 |
|
| 2010 |
Nighot PK, Moeser A, Ali RA, Blikslager AT, Koci MD. Astrovirus infection induces sodium malabsorption and redistributes sodium hydrogen exchanger expression. Virology. 401: 146-54. PMID 20219227 DOI: 10.1016/J.Virol.2010.02.004 |
0.727 |
|
| 2010 |
Nighot PK, Turner RC, Lee SH, Blikslager AT. S1779 The Chloride Channel CLC-2 Modulates Early Barrier Development in CACO-2 Cells Gastroenterology. 138: S-272. DOI: 10.1016/S0016-5085(10)61250-4 |
0.332 |
|
| 2010 |
Nighot PK, Lee SH, Blikslager AT. 580 Intestinal Epithelial Barrier Alterations in CLC-2−/− Mice are Partially Regulated by MLCK Gastroenterology. 138: S-82. DOI: 10.1016/S0016-5085(10)60375-7 |
0.382 |
|
| 2009 |
Nighot PK, Moeser AJ, Ryan KA, Ghashghaei T, Blikslager AT. ClC-2 is required for rapid restoration of epithelial tight junctions in ischemic-injured murine jejunum. Experimental Cell Research. 315: 110-8. PMID 18976652 DOI: 10.1016/J.Yexcr.2008.10.001 |
0.743 |
|
| 2009 |
Nighot PK, Moeser AJ, Blikslager AT. M1698 Clc-2 Regulates Mucosal Barrier Function Associated with Structural Changes to the Villus and Early Co-Localization with Occludin Gastroenterology. 136: A-413. DOI: 10.1016/S0016-5085(09)61898-9 |
0.653 |
|
| 2008 |
Moeser AJ, Nighot PK, Roerig B, Ueno R, Blikslager AT. Comparison of the chloride channel activator lubiprostone and the oral laxative Polyethylene Glycol 3350 on mucosal barrier repair in ischemic-injured porcine intestine. World Journal of Gastroenterology. 14: 6012-7. PMID 18932279 DOI: 10.3748/Wjg.14.6012 |
0.758 |
|
| 2008 |
Moeser AJ, Nighot PK, Ryan KA, Simpson JE, Clarke LL, Blikslager AT. Mice lacking the Na+/H+ exchanger 2 have impaired recovery of intestinal barrier function American Journal of Physiology - Gastrointestinal and Liver Physiology. 295. PMID 18719001 DOI: 10.1152/Ajpgi.00538.2007 |
0.726 |
|
| 2008 |
Nighot PK, Koci MD, Moeser AJ, Ali R, Blikslager AT. W1268 Mechanism of Astrovirus Induced Diarrhea Gastroenterology. 134: A-668. DOI: 10.1016/S0016-5085(08)63119-4 |
0.615 |
|
| 2007 |
Moeser AJ, Ryan KA, Nighot PK, Blikslager AT. Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs American Journal of Physiology - Gastrointestinal and Liver Physiology. 293. PMID 17525151 DOI: 10.1152/Ajpgi.00304.2006 |
0.753 |
|
| 2007 |
Moeser AJ, Nighot PK, Engelke KJ, Ueno R, Blikslager AT. Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the ClC-2 chloride channel, lubiprostone. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G647-56. PMID 17053162 DOI: 10.1152/Ajpgi.00183.2006 |
0.765 |
|
| 2006 |
Moeser AJ, Nighot PK, Ryan KA, Wooten JG, Blikslager AT. Prostaglandin-mediated inhibition of Na+/H+ exchanger isoform 2 stimulates recovery of barrier function in ischemia-injured intestine American Journal of Physiology - Gastrointestinal and Liver Physiology. 291: G885-G894. PMID 16574991 DOI: 10.1152/Ajpgi.00380.2005 |
0.783 |
|
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