☰

Thomas J. Turbyville, Ph.D. - Publications

Affiliations: 
2005 University of Arizona, Tucson, AZ 
Area:
Molecular Biology, Oncology
Tree Info Grants Similar researchers PubMed Report error

21/41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nelson AC, Turbyville TJ, Dharmaiah S, Rigby M, Yang R, Wang TY, Columbus J, Stephens R, Taylor T, Sciacca D, Onsongo G, Sarver A, Subramanian S, Nissley DV, Simanshu DK, et al. internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling. The Journal of Biological Chemistry. PMID 32393580 DOI: 10.1074/Jbc.Ra119.011080  0.344
2020 Goswami D, Chen D, Columbus J, Yang Y, Lightstone F, Turbyville T. Abstract IA07: KRAS4b’s unique diffusion behavior is defined by plasma membrane and effector interactions Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Ras18-Ia07  0.334
2020 Goswami D, Chen D, Columbus J, Turbyville T. Abstract A09: Cooperative membrane interaction between G-domain and HVR defines unique diffusion behavior of KRAS4b Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Ras18-A09  0.317
2020 Columbus J, Turbyville TJ, Wall V, Esposito D, Barda DA, Peng S. Abstract LB-062: A live-cell, protein-protein interaction assay identified inhibitors of KRAS4b-G12D interaction with full-length RAF1 Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Lb-062  0.431
2018 Esposito D, Stephen AG, Turbyville TJ, Holderfield M. New weapons to penetrate the armor: Novel reagents and assays developed at the NCI RAS Initiative to enable discovery of RAS therapeutics. Seminars in Cancer Biology. PMID 29432816 DOI: 10.1016/J.Semcancer.2018.02.006  0.308
2016 Caropreso V, Darvishi E, Turbyville TJ, Ratnayake R, Grohar PJ, McMahon JB, Woldemichael G. Englerin A inhibits EWS-FLI1 DNA Binding in Ewings Sarcoma Cells. The Journal of Biological Chemistry. PMID 26961871 DOI: 10.1074/Jbc.M115.701375  0.643
2015 Brafman A, Gudla P, Nandy K, Columbus J, Chen D, Worthy K, Lockett S, Turbyville T. Abstract 4542: Targeting KRAS4b plasma membrane localization in cells Cancer Research. 75: 4542-4542. DOI: 10.1158/1538-7445.Am2015-4542  0.367
2015 Ye X, Chan KC, Turbyville TJ, Bagni R, Martinko A, Diaz J, Wells J, McCormick F, Whiteley G, Blonder J. Abstract 1996: Surface proteomics of KRASG12V transfected MCF10A cells reveals molecular phenotype of a model cell line expressing oncogenic KRAS Cancer Research. 75: 1996-1996. DOI: 10.1158/1538-7445.Am2015-1996  0.359
2015 Ye X, Turbyville TJ, Bagni R, McCormick F, Whiteley G, Blonder J. Abstract 1829: Comparative surface proteomics of NCI-H2122 cells reveals distinct cell surface phenotype of a metastatic NSCLC cell line expressing oncogenic KRASG12C Cancer Research. 75: 1829-1829. DOI: 10.1158/1538-7445.Am2015-1829  0.392
2014 Lockett S, Verma C, Brafman A, Gudla P, Nandy K, Mimaki Y, Fuchs PL, Jaja J, Reilly KM, Beutler J, Turbyville TJ. Quantitative analysis of F-actin redistribution in astrocytoma cells treated with candidate pharmaceuticals. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 85: 512-21. PMID 24515854 DOI: 10.1002/Cyto.A.22442  0.578
2013 Turbyville T, Brafman A, Chen D, Romanchuck K, Beutler J, Reilly K, Lockett S. Abstract 3429: Coordination of cell cycle repression and reduced cytoskeletal tension by the small molecule natural product, Schweinfurthin A. Cancer Research. 73: 3429-3429. DOI: 10.1158/1538-7445.Am2013-3429  0.624
2012 Woldemichael GM, Turbyville TJ, Vasselli JR, Linehan WM, McMahon JB. Lack of a functional VHL gene product sensitizes renal cell carcinoma cells to the apoptotic effects of the protein synthesis inhibitor verrucarin A. Neoplasia (New York, N.Y.). 14: 771-7. PMID 22952429 DOI: 10.1593/Neo.12852  0.401
2010 Turbyville TJ, Gürsel DB, Tuskan RG, Walrath JC, Lipschultz CA, Lockett SJ, Wiemer DF, Beutler JA, Reilly KM. Schweinfurthin A selectively inhibits proliferation and Rho signaling in glioma and neurofibromatosis type 1 tumor cells in a NF1-GRD-dependent manner. Molecular Cancer Therapeutics. 9: 1234-43. PMID 20442305 DOI: 10.1158/1535-7163.Mct-09-0834  0.572
2009 Cui C, JaJa J, Turbyville T, Beutler J, Gudla P, Nandy K, Lockett S. Quantifying the astrocytoma cell response to candidate pharmaceutical from F-ACTIN image analysis. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 5768-71. PMID 19963655 DOI: 10.1109/IEMBS.2009.5332528  0.513
2009 Wrona IE, Lowe JT, Turbyville TJ, Johnson TR, Beignet J, Beutler JA, Panek JS. Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth. The Journal of Organic Chemistry. 74: 1897-916. PMID 19191575 DOI: 10.1021/Jo802269Q  0.56
2007 McLellan CA, Turbyville TJ, Wijeratne EM, Kerschen A, Vierling E, Queitsch C, Whitesell L, Gunatilaka AA. A rhizosphere fungus enhances Arabidopsis thermotolerance through production of an HSP90 inhibitor. Plant Physiology. 145: 174-82. PMID 17631526 DOI: 10.1104/Pp.107.101808  0.552
2006 Wijeratne EM, Turbyville TJ, Fritz A, Whitesell L, Gunatilaka AA. A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity. Bioorganic & Medicinal Chemistry. 14: 7917-23. PMID 16904330 DOI: 10.1016/J.Bmc.2006.07.048  0.595
2006 Turbyville TJ, Wijeratne EM, Liu MX, Burns AM, Seliga CJ, Luevano LA, David CL, Faeth SH, Whitesell L, Gunatilaka AA. Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desert. Journal of Natural Products. 69: 178-84. PMID 16499313 DOI: 10.1021/Np058095B  0.607
2005 Turbyville TJ, Wijeratne EM, Whitesell L, Gunatilaka AA. The anticancer activity of the fungal metabolite terrecyclic acid A is associated with modulation of multiple cellular stress response pathways. Molecular Cancer Therapeutics. 4: 1569-76. PMID 16227407 DOI: 10.1158/1535-7163.Mct-05-0050  0.605
2004 Wijeratne EM, Carbonezi CA, Takahashi JA, Seliga CJ, Turbyville TJ, Pierson EE, Pierson LS, VanEtten HD, Whitesell L, Bolzani Vda S, Gunatilaka AA. Isolation, optimization of production and structure-activity relationship studies of monocillin I, the cytotoxic constituent of Paraphaeosphaeria quadriseptata. The Journal of Antibiotics. 57: 541-6. PMID 15515894 DOI: 10.7164/Antibiotics.57.541  0.527
2003 Wijeratne EM, Turbyville TJ, Zhang Z, Bigelow D, Pierson LS, VanEtten HD, Whitesell L, Canfield LM, Gunatilaka AA. Cytotoxic constituents of Aspergillus terreus from the rhizosphere of Opuntia versicolor of the Sonoran Desert. Journal of Natural Products. 66: 1567-73. PMID 14695798 DOI: 10.1021/Np030266U  0.591
Low-probability matches (unlikely to be authored by this person)
2020 Goswami D, Chen, Yang Y, Gudla PR, Columbus J, Worthy K, Rigby M, Wheeler M, Mukhopadhyay S, Powell K, Burgan W, Wall V, Esposito D, Simanshu D, Lightstone FC, ... ... Turbyville T, et al. Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior. Elife. 9. PMID 31958057 DOI: 10.7554/Elife.47654  0.291
2013 Nagaoka T, Karasawa H, Turbyville T, Rangel MC, Castro NP, Gonzales M, Baker A, Seno M, Lockett S, Greer YE, Rubin JS, Salomon DS, Bianco C. Cripto-1 enhances the canonical Wnt/β-catenin signaling pathway by binding to LRP5 and LRP6 co-receptors. Cellular Signalling. 25: 178-89. PMID 23022962 DOI: 10.1016/J.Cellsig.2012.09.024  0.284
2011 Woldemichael GM, Turbyville TJ, Linehan WM, McMahon JB. Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Cancer Research. 71: 134-42. PMID 21199801 DOI: 10.1158/0008-5472.CAN-10-0757  0.282
2019 Desir S, Wong P, Turbyville T, Chen, Shetty M, Clark C, Zhai E, Romin Y, Manova-Todorova K, Starr TK, Nissley DV, Steer CJ, Subramanian S, Lou E. Intercellular Transfer of Oncogenic KRAS via Tunneling Nanotubes Introduces Intracellular Mutational Heterogeneity in Colon Cancer Cells. Cancers. 11. PMID 31247990 DOI: 10.3390/Cancers11070892  0.264
2015 Turbyville TJ, Holderfield M. Progress in targeting RAF kinases for cancer therapy. Personalized Medicine. 12: 183-186. PMID 29771643 DOI: 10.2217/Pme.15.1  0.251
2022 Rohban MH, Fuller AM, Tan C, Goldstein JT, Syangtan D, Gutnick A, DeVine A, Nijsure MP, Rigby M, Sacher JR, Corsello SM, Peppler GB, Bogaczynska M, Boghossian A, Ciotti GE, ... ... Turbyville T, et al. Virtual screening for small-molecule pathway regulators by image-profile matching. Cell Systems. PMID 36057257 DOI: 10.1016/j.cels.2022.08.003  0.242
2020 Agamasu C, Chen D, Columbus J, Heinrich F, Tonelli M, Stanley CB, Turbyville T, McCormick F, Nissley DV, Stephen AG. Emerging Insights into the Membrane Binding Domain of RAF Engaging with the Plasma Membrane and its Implication on RAF Activation Biophysical Journal. 118: 496a. DOI: 10.1016/J.Bpj.2019.11.2744  0.236
2020 Goswami D, Chen D, Yang Y, Gudla PR, Columbus J, Worthy K, Rigby M, Wheeler M, Mukhopadhyay S, Powell K, Burgan W, Wall V, Esposito D, Simanshu DK, Lightstone FC, ... ... Turbyville T, et al. Author response: Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior Elife. DOI: 10.7554/Elife.47654.Sa2  0.215
2023 Cuevas-Navarro A, Wagner M, Van R, Swain M, Mo S, Columbus J, Allison MR, Cheng A, Messing S, Turbyville TJ, Simanshu DK, Sale MJ, McCormick F, Stephen AG, Castel P. RAS-dependent RAF-MAPK hyperactivation by pathogenic RIT1 is a therapeutic target in Noonan syndrome-associated cardiac hypertrophy. Science Advances. 9: eadf4766. PMID 37450595 DOI: 10.1126/sciadv.adf4766  0.204
2024 Whitley MJ, Tran TH, Rigby M, Yi M, Dharmaiah S, Waybright TJ, Ramakrishnan N, Perkins S, Taylor T, Messing S, Esposito D, Nissley DV, McCormick F, Stephen AG, Turbyville T, et al. Comparative analysis of KRAS4a and KRAS4b splice variants reveals distinctive structural and functional properties. Science Advances. 10: eadj4137. PMID 38354232 DOI: 10.1126/sciadv.adj4137  0.187
2022 Ingólfsson HI, Neale C, Carpenter TS, Shrestha R, López CA, Tran TH, Oppelstrup T, Bhatia H, Stanton LG, Zhang X, Sundram S, Di Natale F, Agarwal A, Dharuman G, Kokkila Schumacher SIL, ... Turbyville T, et al. Machine learning-driven multiscale modeling reveals lipid-dependent dynamics of RAS signaling proteins. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 34983849 DOI: 10.1073/pnas.2113297119  0.185
2021 Shrestha R, Frank P, Nissley DV, Turbyville TJ. Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes. Iscience. 25: 103608. PMID 35106460 DOI: 10.1016/j.isci.2021.103608  0.164
2024 Shrestha R, Carpenter TS, Van QN, Agamasu C, Tonelli M, Aydin F, Chen D, Gulten G, Glosli JN, López CA, Oppelstrup T, Neale C, Gnanakaran S, Gillette WK, Ingólfsson HI, ... ... Turbyville TJ, et al. Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane. Communications Biology. 7: 242. PMID 38418613 DOI: 10.1038/s42003-024-05916-0  0.163
2023 Morstein J, Shrestha R, Van QN, López CA, Arora N, Tonelli M, Liang H, Chen D, Zhou Y, Hancock JF, Stephen AG, Turbyville TJ, Shokat KM. Direct Modulators of K-Ras-Membrane Interactions. Acs Chemical Biology. PMID 37579045 DOI: 10.1021/acschembio.3c00413  0.159
2021 Van QN, Prakash P, Shrestha R, Balius TE, Turbyville TJ, Stephen AG. RAS Nanoclusters: Dynamic Signaling Platforms Amenable to Therapeutic Intervention. Biomolecules. 11. PMID 33802474 DOI: 10.3390/biom11030377  0.153
2022 Nguyen K, López CA, Neale C, Van QN, Carpenter TS, Di Natale F, Travers T, Tran TH, Chan AH, Bhatia H, Frank PH, Tonelli M, Zhang X, Gulten G, Reddy T, ... ... Turbyville T, et al. Exploring CRD mobility during RAS/RAF engagement at the membrane. Biophysical Journal. PMID 35778842 DOI: 10.1016/j.bpj.2022.06.035  0.125
2024 Columbus J, Turbyville T. Studying RAS Interactions in Live Cells with BRET. Methods in Molecular Biology (Clifton, N.J.). 2797: 253-260. PMID 38570465 DOI: 10.1007/978-1-0716-3822-4_18  0.12
2022 López CA, Zhang X, Aydin F, Shrestha R, Van QN, Stanley CB, Carpenter TS, Nguyen K, Patel LA, Burns V, Hengartner NW, Reddy TJE, Bhatia H, Di Natale F, Tran TH, ... ... Turbyville TJ, et al. Asynchronous Reciprocal Coupling of Martini 2.2 Coarse-Grained and CHARMM36 All-Atom Simulations in an Automated Multiscale Framework. Journal of Chemical Theory and Computation. PMID 35866871 DOI: 10.1021/acs.jctc.2c00168  0.108
2023 Ingólfsson HI, Bhatia H, Aydin F, Oppelstrup T, López CA, Stanton LG, Carpenter TS, Wong S, Di Natale F, Zhang X, Moon JY, Stanley CB, Chavez JR, Nguyen K, Dharuman G, ... ... Turbyville T, et al. Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation Infrastructure. Journal of Chemical Theory and Computation. PMID 37075065 DOI: 10.1021/acs.jctc.2c01018  0.105
2020 Shrestha R, Chen D, Turbyville T. Unraveling the Mystery of Three-State Diffusion Model of KRAS4b on Plasma Membrane Biophysical Journal. 118: 561a. DOI: 10.1016/j.bpj.2019.11.3061  0.046
Hide low-probability matches.