Bradley B. Brasher, Ph.D. - Publications

Affiliations: 
2000 Harvard University, Cambridge, MA, United States 
Area:
Genetics

5/16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Teyra J, Singer AU, Schmitges FW, Jaynes P, Kit Leng Lui S, Polyak MJ, Fodil N, Krieger JR, Tong J, Schwerdtfeger C, Brasher BB, Ceccarelli DFJ, Moffat J, Sicheri F, Moran MF, et al. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure (London, England : 1993). PMID 30713027 DOI: 10.1016/J.Str.2019.01.002  0.428
2002 Roumiantsev S, Shah NP, Gorre ME, Nicoll J, Brasher BB, Sawyers CL, Van Etten RA. Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop. Proceedings of the National Academy of Sciences of the United States of America. 99: 10700-5. PMID 12149456 DOI: 10.1073/Pnas.162140299  0.6
2001 Brasher BB, Roumiantsev S, Van Etten RA. Mutational analysis of the regulatory function of the c-Abl Src homology 3 domain. Oncogene. 20: 7744-52. PMID 11753652 DOI: 10.1038/Sj.Onc.1204978  0.619
2001 Li S, Couvillon AD, Brasher BB, Van Etten RA. Tyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling. The Embo Journal. 20: 6793-804. PMID 11726515 DOI: 10.1093/Emboj/20.23.6793  0.603
2000 Brasher BB, Van Etten RA. c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines. The Journal of Biological Chemistry. 275: 35631-7. PMID 10964922 DOI: 10.1074/Jbc.M005401200  0.611
Low-probability matches (unlikely to be authored by this person)
2017 Kategaya L, Di Lello P, Rougé L, Pastor R, Clark KR, Drummond J, Kleinheinz T, Lin E, Upton JP, Prakash S, Heideker J, McCleland M, Ritorto MS, Alessi DR, Trost M, ... ... Brasher B, et al. USP7 small-molecule inhibitors interfere with ubiquitin binding. Nature. PMID 29045385 DOI: 10.1038/Nature24006  0.289
2019 Pascoe N, Seetharaman A, Teyra J, Manczyk N, Satori MA, Tjandra D, Makhnevych T, Schwerdtfeger C, Brasher BB, Moffat J, Costanzo M, Boone C, Sicheri F, Sidhu S. Yeast Two-Hybrid Analysis for Ubiquitin-Variant Inhibitors of Human Deubiquitinases. Journal of Molecular Biology. PMID 30763569 DOI: 10.1016/J.Jmb.2019.02.007  0.237
2016 Owens CM, Brasher BB, Polemeropoulos A, Rhodin MH, McAllister N, Wong KA, Jones CT, Jiang L, Lin K, Or YS. Preclinical and Clinical Resistance Profile of EDP-239, a Novel HCV NS5A Inhibitor. Antimicrobial Agents and Chemotherapy. PMID 27503644 DOI: 10.1128/Aac.00815-16  0.193
2013 Békés M, Okamoto K, Crist SB, Jones MJ, Chapman JR, Brasher BB, Melandri FD, Ueberheide BM, Denchi EL, Huang TT. DUB-resistant ubiquitin to survey ubiquitination switches in mammalian cells. Cell Reports. 5: 826-38. PMID 24210823 DOI: 10.1016/J.Celrep.2013.10.008  0.166
2021 Rossio V, Paulo JA, Chick J, Brasher B, Gygi SP, King RW. Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity. Cell Chemical Biology. PMID 33417828 DOI: 10.1016/j.chembiol.2020.12.007  0.155
2018 Hewings DS, Heideker J, Ma TP, AhYoung AP, El Oualid F, Amore A, Costakes GT, Kirchhofer D, Brasher B, Pillow T, Popovych N, Maurer T, Schwerdtfeger C, Forrest WF, Yu K, et al. Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes. Nature Communications. 9: 1162. PMID 29563501 DOI: 10.1038/S41467-018-03511-6  0.138
2016 Owens CM, Brasher BB, Polemeropoulos A, Rhodin MH, McAllister N, Peng X, Wang C, Ying L, Cao H, Lawitz E, Poordad F, Rondon J, Box TD, Zeuzem S, Buggisch P, et al. Preclinical Profile and Clinical Efficacy of a Novel HCV NS5A Inhibitor, EDP-239. Antimicrobial Agents and Chemotherapy. PMID 27503640 DOI: 10.1128/Aac.00808-16  0.117
2018 Liu P, Gan W, Su S, Hauenstein AV, Fu TM, Brasher B, Schwerdtfeger C, Liang AC, Xu M, Wei W. K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair. Science Signaling. 11. PMID 29871913 DOI: 10.1126/Scisignal.Aar8133  0.112
2009 Jiang L, Gai Y, Middleton T, Kurtz K, Lu L, Liu S, Phan T, Luo X, Poon T, Brasher B, McDaniel K, Kempf D, Or Y. 8 POTENT HCV PROTEASE INHIBITORS WITH THE POTENTIAL FOR ONCE-DAILY DOSING AND BROAD GENOTYPE COVERAGE Journal of Hepatology. 50: S6. DOI: 10.1016/S0168-8278(09)60010-6  0.075
2003 Vincent S, Thomas A, Brasher B, Benson JD. Targeting of proteins to membranes through hedgehog auto-processing. Nature Biotechnology. 21: 936-40. PMID 12858181 DOI: 10.1038/nbt844  0.058
2003 Vincent S, Thomas A, Brasher B, Benson JD. Erratum: Targeting of proteins to membranes through hedgehog auto-processing Nature Biotechnology. 21: 1098-1098. DOI: 10.1038/nbt0903-1098b  0.058
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