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Patrick D. Sutphin, Ph.D. - Publications

Affiliations: 
2007 Stanford University, Palo Alto, CA 
Area:
Molecular Biology, Oncology
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Underwood JJ, Quadri RS, Kalva SP, Shah H, Sanjeeviah AR, Beg MS, Sutphin PD. Liquid Biopsy for Cancer: Review and Implications for the Radiologist. Radiology. 182584. PMID 31746691 DOI: 10.1148/Radiol.2019182584  0.357
2019 Rodriguez S, Andring B, Nguyen T, Tellapuri S, Sutphin P, Kalva S. 03:09 PM Abstract No. 336 Renal angiomyolipoma: 3D volumetric assessment of tumor components to evaluate tumor reduction following embolization Journal of Vascular and Interventional Radiology. 30. DOI: 10.1016/J.Jvir.2018.12.406  0.35
2011 Chan DA, Sutphin PD, Nguyen P, Turcotte S, Lai EW, Banh A, Reynolds GE, Chi JT, Wu J, Solow-Cordero DE, Bonnet M, Flanagan JU, Bouley DM, Graves EE, Denny WA, et al. Targeting GLUT1 and the Warburg effect in renal cell carcinoma by chemical synthetic lethality. Science Translational Medicine. 3: 94ra70. PMID 21813754 DOI: 10.1126/Scitranslmed.3002394  0.719
2010 Hay MP, Turcotte S, Flanagan JU, Bonnet M, Chan DA, Sutphin PD, Nguyen P, Giaccia AJ, Denny WA. 4-Pyridylanilinothiazoles that selectively target von Hippel-Lindau deficient renal cell carcinoma cells by inducing autophagic cell death. Journal of Medicinal Chemistry. 53: 787-97. PMID 19994864 DOI: 10.1021/Jm901457W  0.699
2009 Chan DA, Kawahara TL, Sutphin PD, Chang HY, Chi JT, Giaccia AJ. Tumor vasculature is regulated by PHD2-mediated angiogenesis and bone marrow-derived cell recruitment. Cancer Cell. 15: 527-38. PMID 19477431 DOI: 10.1016/J.Ccr.2009.04.010  0.722
2008 Choi CY, Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS, Giaccia AJ. Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice. Molecular Imaging. 7: 139-46. PMID 19123984  0.757
2008 Turcotte S, Sutphin PD, Giaccia AJ. Targeted therapy for the loss of von Hippel-Lindau in renal cell carcinoma: a novel molecule that induces autophagic cell death. Autophagy. 4: 944-6. PMID 18769110 DOI: 10.4161/Auto.6785  0.544
2008 Turcotte S, Chan DA, Sutphin PD, Hay MP, Denny WA, Giaccia AJ. A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Cancer Cell. 14: 90-102. PMID 18598947 DOI: 10.1016/J.Ccr.2008.06.004  0.713
2008 Giaccia AJ, Choi CYH, Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS. Molecular imaging of hypoxia-inducible factor 1α and von Hippel-Lindau interaction in mice Molecular Imaging. 7: 139-146. DOI: 10.2310/7290.2008.00017  0.738
2007 Cecic I, Chan DA, Sutphin PD, Ray P, Gambhir SS, Giaccia AJ, Graves EE. Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia. Molecular Imaging. 6: 219-28. PMID 17711777 DOI: 10.2310/7290.2007.00017  0.711
2007 Sutphin PD, Chan DA, Li JM, Turcotte S, Krieg AJ, Giaccia AJ. Targeting the loss of the von Hippel-Lindau tumor suppressor gene in renal cell carcinoma cells. Cancer Research. 67: 5896-905. PMID 17575159 DOI: 10.1158/0008-5472.Can-07-0604  0.711
2007 Sutphin PD, Giaccia AJ, Chan DA. Energy regulation: HIF MXIes it up with the C-MYC powerhouse. Developmental Cell. 12: 845-6. PMID 17543856 DOI: 10.1016/J.Devcel.2007.05.006  0.688
2007 Cairns RA, Papandreou I, Sutphin PD, Denko NC. Metabolic targeting of hypoxia and HIF1 in solid tumors can enhance cytotoxic chemotherapy. Proceedings of the National Academy of Sciences of the United States of America. 104: 9445-50. PMID 17517659 DOI: 10.1073/Pnas.0611662104  0.433
2007 Cecic I, Chan DA, Sutphin PD, Ray P, Gambhir SS, Giaccia AJ, Graves EE. Oxygen Sensitivity of Reporter Genes: Implications for Preclinical Imaging of Tumor Hypoxia Molecular Imaging. 6: 7290.2007.00017. DOI: 10.2310/7290.2007.00017  0.692
2006 Petrik D, Lavori PW, Cao H, Zhu Y, Wong P, Christofferson E, Kaplan MJ, Pinto HA, Sutphin P, Koong AC, Giaccia AJ, Le QT. Plasma osteopontin is an independent prognostic marker for head and neck cancers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 5291-7. PMID 17114663 DOI: 10.1200/Jco.2006.06.8627  0.567
2006 Dornhöfer N, Spong S, Bennewith K, Salim A, Klaus S, Kambham N, Wong C, Kaper F, Sutphin P, Nacamuli R, Nacalumi R, Höckel M, Le Q, Longaker M, Yang G, et al. Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. Cancer Research. 66: 5816-27. PMID 16740721 DOI: 10.1158/0008-5472.Can-06-0081  0.771
2006 Dornhöfer N, Spong S, Bennewith K, Salim A, Klaus S, Kambham N, Wong C, Kaper F, Sutphin P, Nacamuli R, Höckel M, Le Q, Longaker M, Yang G, Koong A, et al. Erratum: Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis (Cancer Research (June 1, 2006) 66 (5816-5827)) Cancer Research. 66. DOI: 10.1158/0008-5472.Can-66-15-Cor  0.756
2006 Choi C, Paulmurugan R, Chan D, Sutphin P, Le Q, Koong A, Gambhir S, Giaccia A. 83 International Journal of Radiation Oncology*Biology*Physics. 66: S48-S49. DOI: 10.1016/J.Ijrobp.2006.07.113  0.704
2005 Petrik DW, Cao H, Zhu Y, Wong P, Sutphin P, Giaccia AJ, Koong AA, Le QT. An expanded study of the relationship between osteopontin, tumor pO2 and prognosis in head and neck squamous cell carcinomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 5521. PMID 27945243 DOI: 10.1200/Jco.2005.23.16_Suppl.5521  0.535
2005 Chan DA, Sutphin PD, Yen SE, Giaccia AJ. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha. Molecular and Cellular Biology. 25: 6415-26. PMID 16024780 DOI: 10.1128/Mcb.25.15.6415-6426.2005  0.711
2005 Zhu Y, Denhardt DT, Cao H, Sutphin PD, Koong AC, Giaccia AJ, Le QT. Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a Ras-activated enhancer. Oncogene. 24: 6555-63. PMID 16007184 DOI: 10.1038/Sj.Onc.1208800  0.649
2004 Bemis L, Chan DA, Finkielstein CV, Qi L, Sutphin PD, Chen X, Stenmark K, Giaccia AJ, Zundel W. Distinct aerobic and hypoxic mechanisms of HIF-alpha regulation by CSN5. Genes & Development. 18: 739-44. PMID 15082527 DOI: 10.1101/Gad.1180104  0.752
2004 Sutphin PD, Chan DA, Giaccia AJ. Dead cells don't form tumors: HIF-dependent cytotoxins. Cell Cycle (Georgetown, Tex.). 3: 160-3. PMID 14712081  0.727
2004 Sutphin PD, Chan DA, Giaccia AJ. Dead Cells Don’t Form Tumors: HIF-Dependent Cytotoxins Cell Cycle. 3: 160-163. DOI: 10.4161/Cc.3.2.617  0.742
2003 Denko NC, Fontana LA, Hudson KM, Sutphin PD, Raychaudhuri S, Altman R, Giaccia AJ. Investigating hypoxic tumor physiology through gene expression patterns. Oncogene. 22: 5907-14. PMID 12947397 DOI: 10.1038/Sj.Onc.1206703  0.555
2003 Le QT, Sutphin PD, Raychaudhuri S, Yu SC, Terris DJ, Lin HS, Lum B, Pinto HA, Koong AC, Giaccia AJ. Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 59-67. PMID 12538452  0.599
2002 Chan DA, Sutphin PD, Denko NC, Giaccia AJ. Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha. The Journal of Biological Chemistry. 277: 40112-7. PMID 12186875 DOI: 10.1074/Jbc.M206922200  0.716
2002 Choi C, Fontana L, Sutphin P, Hammond E, Denko N, Giaccia A, Koong A, Le Q. Adipophilin: a novel hypoxia regulated gene International Journal of Radiation Oncology*Biology*Physics. 54: 121. DOI: 10.1016/S0360-3016(02)03265-0  0.591
2001 Koumenis C, Alarcon R, Hammond E, Sutphin P, Hoffman W, Murphy M, Derr J, Taya Y, Lowe SW, Kastan M, Giaccia A. Regulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Molecular and Cellular Biology. 21: 1297-310. PMID 11158315 DOI: 10.1128/Mcb.21.4.1297-1310.2001  0.486
2001 Sutphin PD, Raychaudhuri S, Denko NC, Altman RB, Giaccia AJ. Application of supervised machine learning to identify genes associated with the hypoxia response Nature Genetics. 27: 90-90. DOI: 10.1038/87320  0.447
2001 Le Q, Sutphin P, Raychaudhuri S, Terris D, Lin H, Koong A, Chen U, Tibshirani R, Denko N, Giaccia A. Osteopontin - a new serum marker for tumor hypoxia International Journal of Radiation Oncology*Biology*Physics. 51: 80. DOI: 10.1016/S0360-3016(01)01971-X  0.623
1998 Whitesell L, Sutphin PD, Pulcini EJ, Martinez JD, Cook PH. The physical association of multiple molecular chaperone proteins with mutant p53 is altered by geldanamycin, an hsp90-binding agent. Molecular and Cellular Biology. 18: 1517-24. PMID 9488468 DOI: 10.1128/Mcb.18.3.1517  0.323
1997 Whitesell L, Sutphin P, An WG, Schulte T, Blagosklonny MV, Neckers L. Geldanamycin-stimulated destabilization of mutated p53 is mediated by the proteasome in vivo. Oncogene. 14: 2809-2816. PMID 9190897 DOI: 10.1038/Sj.Onc.1201120  0.319
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