| Year |
Citation |
Score |
| 2019 |
Velcicky J, Mathison CJN, Nikulin V, Pflieger D, Epple R, Azimioara M, Cow C, Michellys PY, Rigollier P, Beisner DR, Bodendorf U, Guerini D, Liu B, Wen B, Zaharevitz S, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. Acs Medicinal Chemistry Letters. 10: 887-892. PMID 31223443 DOI: 10.1021/acsmedchemlett.9b00044 |
0.679 |
|
| 2018 |
Velcicky J, Bodendorf U, Rigollier P, Epple R, Beisner DR, Guerini D, Smith P, Liu B, Feifel R, Wipfli P, Aichholz R, Couttet P, Dix I, Widmer T, Wen B, et al. Discovery of the First Potent, Selective, and Orally Bioavailable Signal Peptide Peptidase-Like 2a (SPPL2a) Inhibitor Displaying Pronounced Immunomodulatory Effects In Vivo. Journal of Medicinal Chemistry. PMID 29359565 DOI: 10.1021/Acs.Jmedchem.7B01371 |
0.678 |
|
| 2015 |
Miller AT, Dahlberg C, Sandberg ML, Wen BG, Beisner DR, Hoerter JA, Parker A, Schmedt C, Stinson M, Avis J, Cienfuegos C, McPate M, Tranter P, Gosling M, Groot-Kormelink PJ, et al. Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease. Plos One. 10: e0131071. PMID 26121493 DOI: 10.1371/journal.pone.0131071 |
0.7 |
|
| 2013 |
Beisner DR, Langerak P, Parker AE, Dahlberg C, Otero FJ, Sutton SE, Poirot L, Barnes W, Young MA, Niessen S, Wiltshire T, Bodendorf U, Martoglio B, Cravatt B, Cooke MP. The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain. The Journal of Experimental Medicine. 210: 23-30. PMID 23267013 DOI: 10.1084/Jem.20121072 |
0.516 |
|
| 2010 |
Kerdiles YM, Stone EL, Beisner DR, Beisner DL, McGargill MA, Ch'en IL, Stockmann C, Katayama CD, Hedrick SM. Foxo transcription factors control regulatory T cell development and function. Immunity. 33: 890-904. PMID 21167754 DOI: 10.1016/J.Immuni.2010.12.002 |
0.667 |
|
| 2009 |
Dejean AS, Beisner DR, Ch'en IL, Kerdiles YM, Babour A, Arden KC, Castrillon DH, DePinho RA, Hedrick SM. Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nature Immunology. 10: 504-13. PMID 19363483 DOI: 10.1038/Ni.1729 |
0.698 |
|
| 2009 |
Miller AT, Beisner DR, Liu D, Cooke MP. Inositol 1,4,5-trisphosphate 3-kinase B is a negative regulator of BCR signaling that controls B cell selection and tolerance induction. Journal of Immunology (Baltimore, Md. : 1950). 182: 4696-704. PMID 19342645 DOI: 10.4049/Jimmunol.0802850 |
0.476 |
|
| 2009 |
Kerdiles YM, Beisner DR, Tinoco R, Dejean AS, Castrillon DH, DePinho RA, Hedrick SM. Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nature Immunology. 10: 176-84. PMID 19136962 DOI: 10.1038/Ni.1689 |
0.647 |
|
| 2008 |
Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, Hedrick SM. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proceedings of the National Academy of Sciences of the United States of America. 105: 17463-8. PMID 18981423 DOI: 10.1073/Pnas.0808043105 |
0.697 |
|
| 2008 |
Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, Hedrick SM. Caspase‐8 regulates a form of death that is distinct from apoptosis in T cells The Faseb Journal. 22: 369-369. DOI: 10.1096/Fasebj.22.2_Supplement.369 |
0.665 |
|
| 2005 |
Beisner DR, Ch'en IL, Kolla RV, Hoffmann A, Hedrick SM. Cutting edge: innate immunity conferred by B cells is regulated by caspase-8. Journal of Immunology (Baltimore, Md. : 1950). 175: 3469-73. PMID 16148088 DOI: 10.4049/Jimmunol.175.6.3469 |
0.686 |
|
| 2003 |
Beisner DR, Chu IH, Arechiga AF, Hedrick SM, Walsh CM. The requirements for Fas-associated death domain signaling in mature T cell activation and survival. Journal of Immunology (Baltimore, Md. : 1950). 171: 247-56. PMID 12817005 DOI: 10.4049/Jimmunol.171.1.247 |
0.713 |
|
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