Aaron D. Bossler, Ph.D. - Publications

Affiliations: 
2001 University of Iowa, Iowa City, IA 
Area:
Molecular Biology

12/59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Goel A, Nishikawa K, Futaya E, Poylak I, Holt R, Li M, Sagastum E, Marks B, Bossler AD, Johnson FL, Schultz MK, Goda H, Okada H, Orcutt K, Abe G, et al. Abstract LB-230: Quantitative immunohistochemistry for melanocortin 1 receptor using phosphor integrated dots Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Lb-230  0.301
2018 Guseva NV, Jaber O, Stence AA, Sompallae K, Bashir A, Sompallae R, Bossler AD, Jensen CS, Ma D. Simultaneous detection of single-nucleotide variant, deletion/insertion, and fusion in lung and thyroid carcinoma using cytology specimen and an RNA-based next-generation sequencing assay. Cancer Cytopathology. PMID 29364576 DOI: 10.1002/Cncy.21963  0.305
2017 Ferrand C, Deschamps M, Levitas A, Lockwood C, Payton JE, Uy GL, Schiffer CA, Feldman G, Bossler A, Woolworth J, Mims AS, Shridhar K, Wu N, Huang S, Wei H, et al. Xpert® BCR-ABL Ultra, a High Sensitivity Assay, Demonstrates a Limit of Detection Reaching MR4.5 and below Blood. 130: 1610-1610. DOI: 10.1182/Blood.V130.Suppl_1.1610.1610  0.302
2016 Tilak A, Sompallae R, Stence A, Guseva N, Bossler A. Abstract 01: Development of a targeted panel for acute myeloid leukemia (AML) by using next-generation sequencing (NGS) Clinical Cancer Research. 22: 1-1. DOI: 10.1158/1557-3265.Pmsclingen15-01  0.328
2010 Harris G, Bossler A. PTPN13 Expression Correlates with Survival in HPV+ HNSCC Otolaryngology–Head and Neck Surgery. 143: P70-P70. DOI: 10.1016/J.Otohns.2010.06.093  0.395
2009 Lace MJ, Anson JR, Klingelhutz AJ, Lee JH, Bossler AD, Haugen TH, Turek LP. Human papillomavirus (HPV) type 18 induces extended growth in primary human cervical, tonsillar, or foreskin keratinocytes more effectively than other high-risk mucosal HPVs. Journal of Virology. 83: 11784-94. PMID 19740985 DOI: 10.1128/Jvi.01370-09  0.612
2009 Hoover AC, Strand GL, Nowicki PN, Anderson ME, Vermeer PD, Klingelhutz AJ, Bossler AD, Pottala JV, Hendriks WJ, Lee JH. Impaired PTPN13 phosphatase activity in spontaneous or HPV-induced squamous cell carcinomas potentiates oncogene signaling through the MAP kinase pathway. Oncogene. 28: 3960-70. PMID 19734941 DOI: 10.1038/Onc.2009.251  0.36
2009 Lace MJ, Anson JR, Klingelhutz AJ, Harada H, Taniguchi T, Bossler AD, Haugen TH, Turek LP. Interferon-beta treatment increases human papillomavirus early gene transcription and viral plasmid genome replication by activating interferon regulatory factor (IRF)-1. Carcinogenesis. 30: 1336-44. PMID 19541854 DOI: 10.1093/Carcin/Bgp150  0.617
2009 Nowicki P, Hoover A, De Geest K, Goodheart M, Lace M, Haugen T, Turek L, Strand G, Bossler A, Klingelhutz A, Lee J. Protein tyrosine phosphatase nonreceptor 13 (PTPN13) is targeted by human papillomavirus 16 E6 in cervical epithelium Infectious Agents and Cancer. 4. DOI: 10.1186/1750-9378-4-S2-P31  0.593
2009 Hoover A, Strand G, Nowicki P, Anderson M, Klingelhutz A, Bossler A, Lee J. An invasion mechanism for human papillomavirus related cancers: HPV 16 E6 degrades PTPN13 allowing enhanced map kinase signaling Infectious Agents and Cancer. 4: 1-1. DOI: 10.1186/1750-9378-4-S2-O13  0.423
2008 Spanos WC, Hoover A, Harris GF, Wu S, Strand GL, Anderson ME, Klingelhutz AJ, Hendriks W, Bossler AD, Lee JH. The PDZ binding motif of human papillomavirus type 16 E6 induces PTPN13 loss, which allows anchorage-independent growth and synergizes with ras for invasive growth. Journal of Virology. 82: 2493-500. PMID 18160445 DOI: 10.1128/Jvi.02188-07  0.412
2008 Spanos WC, Geiger J, Anderson ME, Harris GF, Bossler AD, Smith RB, Klingelhutz AJ, Lee JH. Deletion of the PDZ motif of HPV16 E6 preventing immortalization and anchorage-independent growth in human tonsil epithelial cells. Head & Neck. 30: 139-47. PMID 17657785 DOI: 10.1002/Hed.20673  0.429
Low-probability matches (unlikely to be authored by this person)
2018 Monga V, Swami U, Tanas M, Bossler A, Mott SL, Smith BJ, Milhem M. A Phase I/II Study Targeting Angiogenesis Using Bevacizumab Combined with Chemotherapy and a Histone Deacetylase Inhibitor (Valproic Acid) in Advanced Sarcomas. Cancers. 10. PMID 29462961 DOI: 10.3390/Cancers10020053  0.293
2016 Guseva NV, Jaber O, Tanas MR, Stence AA, Sompallae R, Schade J, Fillman AN, Miller BJ, Bossler AD, Ma D. Anchored multiplex PCR for targeted next-generation sequencing reveals recurrent and novel USP6 fusions and upregulation of USP6 expression in aneurysmal bone cyst. Genes, Chromosomes & Cancer. PMID 27910166 DOI: 10.1002/Gcc.22432  0.292
2015 Day G, Lockwood C, Payton JE, Uy GL, Schiffer C, Feldman G, Bossler A, Woolworth J, Mims AS, Levitas A, Shridhar K, Huang S, Xiao V, Wu N, Bates MP, et al. Development of Xpert® BCR-ABL Ultra, an Automated and Standardized Multiplex Assay with Required Performance Characteristics for BCR-ABL1 Quantitative Measurement on an International Reporting Scale Blood. 126: 2793-2793. DOI: 10.1182/Blood.V126.23.2793.2793  0.291
2016 Guseva NV, Tanas MR, Stence AA, Sompallae R, Schade JC, Bossler AD, Bellizzi AM, Ma D. The NAB2-STAT6 gene fusion in solitary fibrous tumor can be reliably detected by anchored multiplexed PCR for targeted next-generation sequencing. Cancer Genetics. PMID 27292373 DOI: 10.1016/J.Cancergen.2016.05.071  0.29
2018 Sande CM, Chang B, Monga V, Bossler AD, Ma D. Biallelic TP53 gain of function mutations in rapidly progressing solid tumors. Cancer Genetics. 222: 20-24. PMID 29666004 DOI: 10.1016/J.Cancergen.2018.02.001  0.283
2019 Swami U, Monga V, Freesmeier M, Zhang W, Bossler AD, Zakharia Y, Milhem M. Exceptional responses with sequential metronomic temozolomide after pembrolizumab failure in patients with metastatic melanoma. Melanoma Research. PMID 30829928 DOI: 10.1097/Cmr.0000000000000592  0.282
2018 Grogan N, Swami U, Bossler AD, Zakharia Y, Milhem M. Toxicities with targeted therapies after immunotherapy in metastatic melanoma. Melanoma Research. PMID 30086073 DOI: 10.1097/Cmr.0000000000000493  0.282
2006 Link BK, Ballas ZK, Weisdorf D, Wooldridge JE, Bossler AD, Shannon M, Rasmussen WL, Krieg AM, Weiner GJ. Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma. Journal of Immunotherapy (Hagerstown, Md. : 1997). 29: 558-68. PMID 16971811 DOI: 10.1097/01.Cji.0000211304.60126.8F  0.278
2018 Swami U, Monga V, Tanas M, Bossler A, Mott S, Smith B, Milhem M. Abstract B23: A pilot study targeting angiogenesis using bevacizumab combined with gemcitabine/docetaxel and valproic acid (VPA), a histone deacetylase inhibitor (HDACi), in advanced soft tissue sarcomas (STS) Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-B23  0.275
2006 Bossler AD, Richards J, George C, Godmilow L, Ganguly A. Novel mutations in ENG and ACVRL1 identified in a series of 200 individuals undergoing clinical genetic testing for hereditary hemorrhagic telangiectasia (HHT): correlation of genotype with phenotype. Human Mutation. 27: 667-75. PMID 16752392 DOI: 10.1002/Humu.20342  0.275
2019 Swami U, Monga V, Bossler AD, Zakharia Y, Milhem M. Durable Clinical Benefit in Patients with Advanced Cutaneous Melanoma after Discontinuation of Anti-PD-1 Therapies Due to Immune-Related Adverse Events. Journal of Oncology. 2019: 1856594. PMID 31428149 DOI: 10.1155/2019/1856594  0.268
2014 Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, ... ... Bossler A, et al. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biology. 15: R53. PMID 24667040 DOI: 10.1186/Gb-2014-15-3-R53  0.268
2016 Sabatini LM, Mathews C, Ptak D, Doshi S, Tynan K, Hegde MR, Burke TL, Bossler AD. Genomic Sequencing Procedure Microcosting Analysis and Health Economic Cost-Impact Analysis: A Report of the Association for Molecular Pathology. The Journal of Molecular Diagnostics : Jmd. 18: 319-28. PMID 27080370 DOI: 10.1016/J.Jmoldx.2015.11.010  0.264
2017 Zakharia Y, Monga V, Swami U, Bossler AD, Freesmeier M, Frees M, Khan M, Frydenlund N, Srikantha R, Vanneste M, Henry M, Milhem M. Targeting epigenetics for treatment of BRAF mutated metastatic melanoma with decitabine in combination with vemurafenib: A phase lb study. Oncotarget. 8: 89182-89193. PMID 29179510 DOI: 10.18632/Oncotarget.21269  0.262
2019 Xiu Y, Dong Q, Fu L, Bossler A, Tang X, Boyce B, Borcherding N, Leidinger M, Sardina JL, Xue HH, Li Q, Feldman A, Aifantis I, Boccalatte F, Wang L, et al. Coactivation of NF-κB and Notch signaling is sufficient to induce B cell transformation and enables B-myeloid conversion. Blood. PMID 31697816 DOI: 10.1182/Blood.2019001438  0.25
2017 Wessels D, Lusche DF, Voss E, Kuhl S, Buchele EC, Klemme MR, Russell KB, Ambrose J, Soll BA, Bossler A, Milhem M, Goldman C, Soll DR. Melanoma cells undergo aggressive coalescence in a 3D Matrigel model that is repressed by anti-CD44. Plos One. 12: e0173400. PMID 28264026 DOI: 10.1371/Journal.Pone.0173400  0.249
2007 Wang HY, Bossler AD, Schaffer A, Tomczak E, DiPatri D, Frank DM, Nowell PC, Bagg A. A novel t(3;8)(q27;q24.1) simultaneously involving both the BCL6 and MYC genes in a diffuse large B-cell lymphoma. Cancer Genetics and Cytogenetics. 172: 45-53. PMID 17175379 DOI: 10.1016/J.Cancergencyto.2006.07.016  0.248
2018 Swami U, Monga V, Knutson T, Bossler AD, Zakharia Y, Milhem MM. Prognostic markers for progression free survival (PFS) to anti PD-1 therapies in metastatic melanoma. Journal of Clinical Oncology. 36: e21527-e21527. DOI: 10.1200/Jco.2018.36.15_Suppl.E21527  0.247
2018 Brogden KA, Parashar D, Hallier AR, Braun T, Qian F, Rizvi NA, Bossler AD, Milhem MM, Chan TA, Abbasi T, Vali S. Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy. Bmc Cancer. 18: 225. PMID 29486723 DOI: 10.1186/S12885-018-4134-Y  0.242
2018 Larson AA, Baker PR, Milev MP, Press CA, Sokol RJ, Cox MO, Lekostaj JK, Stence AA, Bossler AD, Mueller JM, Prematilake K, Tadjo TF, Williams CA, Sacher M, Moore SA. TRAPPC11 and GOSR2 mutations associate with hypoglycosylation of α-dystroglycan and muscular dystrophy. Skeletal Muscle. 8: 17. PMID 29855340 DOI: 10.1186/S13395-018-0163-0  0.238
2003 Bossler AD, Richter SS, Chavez AJ, Vogelgesang SA, Sutton DA, Grooters AM, Rinaldi MG, de Hoog GS, Pfaller MA. Exophiala oligosperma causing olecranon bursitis. Journal of Clinical Microbiology. 41: 4779-82. PMID 14532219 DOI: 10.1128/Jcm.41.10.4779-4782.2003  0.237
2016 Steussy B, Lekostaj J, Qian Q, Rosenthal N, Holman CJ, Syrbu S, Darbro B, Bossler A, Karandikar NJ. Leukemic Transdifferentiation of Follicular Lymphoma Into an Acute Histiocytic Leukemia in a 52-Year-Old Caucasian Woman. Laboratory Medicine. 47: 155-7. PMID 27069033 DOI: 10.1093/Labmed/Lmw011  0.236
2018 Brogden KA, Parashar D, Hallier AR, Braun T, Qian F, Rizvi NA, Bossler AD, Milhem MM, Chan TA, Abbasi T, Vali S. Correction to: Genomics of NSCLC patients both affirm PD-L1 expression and predict their clinical responses to anti-PD-1 immunotherapy. Bmc Cancer. 18: 413. PMID 29649990 DOI: 10.1186/S12885-018-4200-5  0.234
2014 Snow AN, Stence AA, Pruessner JA, Bossler AD, Ma D. A simple and cost-effective method of DNA extraction from small formalin-fixed paraffin-embedded tissue for molecular oncologic testing. Bmc Clinical Pathology. 14: 30. PMID 25067909 DOI: 10.1186/1472-6890-14-30  0.23
2015 Clamon GH, Bossler AD, Abu Hejleh T, Furqan M. Germline mutations predisposing to non-small cell lung cancer. Familial Cancer. 14: 463-9. PMID 25813228 DOI: 10.1007/S10689-015-9796-X  0.229
2012 Marko DC, Saffert RT, Cunningham SA, Hyman J, Walsh J, Arbefeville S, Howard W, Pruessner J, Safwat N, Cockerill FR, Bossler AD, Patel R, Richter SS. Evaluation of the Bruker Biotyper and Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry systems for identification of nonfermenting gram-negative bacilli isolated from cultures from cystic fibrosis patients. Journal of Clinical Microbiology. 50: 2034-9. PMID 22495566 DOI: 10.1128/Jcm.00330-12  0.217
2010 Shenoy AM, Markowitz JA, Bonnemann CG, Krishnamoorthy K, Bossler AD, Tseng BS. Muscle-Eye-Brain disease. Journal of Clinical Neuromuscular Disease. 11: 124-6. PMID 20215985 DOI: 10.1097/Cnd.0B013E3181C5054D  0.213
2011 Bossler A, Gunsolly C, Pyne MT, Rendo A, Rachel J, Mills R, Miller M, Sipley J, Hillyard D, Jenkins S, Essmyer C, Young S, Lewinski M, Rennert H. Performance of the COBAS® AmpliPrep/COBAS TaqMan® automated system for hepatitis C virus (HCV) quantification in a multi-center comparison Journal of Clinical Virology. 50: 100-103. PMID 21145783 DOI: 10.1016/J.Jcv.2010.10.020  0.21
2010 Tsumagari K, Chen D, Hackman JR, Bossler AD, Ehrlich M. FSH dystrophy and a subtelomeric 4q haplotype: a new assay and associations with disease. Journal of Medical Genetics. 47: 745-51. PMID 20710047 DOI: 10.1136/Jmg.2009.076703  0.21
2019 Isaacson AL, Guseva NV, Bossler AD, Ma D. Urothelial carcinoma with an NRF1/BRAF rearrangement and response to targeted therapy. Cold Spring Harbor Molecular Case Studies. PMID 31010895 DOI: 10.1101/mcs.a003848  0.185
2019 Jones KA, Bossler AD, Bellizzi AM, Snow AN. fusion in a low-grade glioma with distinctive morphology and unexpected aggressive behavior. Cold Spring Harbor Molecular Case Studies. 5. PMID 30936198 DOI: 10.1101/mcs.a003855  0.181
2021 Alwaqfi RR, Samuelson MI, Guseva NN, Ouyang M, Bossler AD, Ma D. PTCH1-GLI1 Fusion-Positive Ovarian Tumor: Report of a Unique Case With Response to Tyrosine Kinase Inhibitor Pazopanib. Journal of the National Comprehensive Cancer Network : Jnccn. 19: 998-1004. PMID 34551385 DOI: 10.6004/jnccn.2021.7058  0.165
2020 Swami U, Chennamadhavuni A, Borcherding N, Bossler AD, Mott SL, Garje R, Zakharia Y, Milhem M. Multivariable Analysis of 169 Cases of Advanced Cutaneous Melanoma to Evaluate Antibiotic Exposure as Predictor of Survival to Anti-PD-1 Based Immunotherapies. Antibiotics (Basel, Switzerland). 9. PMID 33120998 DOI: 10.3390/antibiotics9110740  0.149
2023 Sompallae RR, Dundar B, Guseva NV, Bossler AD, Ma D. and exon 20 insertion/duplication in advanced non-small cell lung cancer: genomic profiling and clinicopathologic features. Frontiers in Oncology. 13: 1163485. PMID 37284196 DOI: 10.3389/fonc.2023.1163485  0.146
2023 Iqbal MA, Broeckel U, Levy B, Skinner S, Sahajpal NS, Rodriguez V, Stence A, Awayda K, Scharer G, Skinner C, Stevenson R, Bossler A, Nagy PL, Kolhe R. Multisite Assessment of Optical Genome Mapping for Analysis of Structural Variants in Constitutional Postnatal Cases. The Journal of Molecular Diagnostics : Jmd. 25: 175-188. PMID 36828597 DOI: 10.1016/j.jmoldx.2022.12.005  0.143
2022 Isaacson AL, Sompallae RR, Guseva NV, Bellizzi AM, Bossler AD, Ma D. Genomic Profiling of Metastatic Uveal Melanoma Shows Frequent Coexisting BAP1 or SF3B1 and GNAQ/GNA11 Mutations and Correlation With Prognosis. American Journal of Clinical Pathology. PMID 35212356 DOI: 10.1093/ajcp/aqac019  0.142
2022 Cheung K, Bossler AD, Mott SL, Zeisler M, McKillip J, Zakharia Y, Swick BL, Powers JG. The Genetics of Early-Stage Melanoma in a Veteran Population. Frontiers in Oncology. 12: 887768. PMID 35712493 DOI: 10.3389/fonc.2022.887768  0.124
2021 Rieth JM, Swami U, Mott SL, Zanaty M, Henry MD, Bossler AD, Greenlee JD, Zakharia Y, Vanneste M, Jennings B, Milhem MM. Melanoma Brain Metastases in the Era of Targeted Therapy and Checkpoint Inhibitor Therapy. Cancers. 13. PMID 33804910 DOI: 10.3390/cancers13071489  0.122
2022 Furqan M, Abu-Hejleh T, Stephens LM, Hartwig SM, Mott SL, Pulliam CF, Petronek M, Henrich JB, Fath MA, Houtman JC, Varga SM, Bodeker KL, Bossler AD, Bellizzi AM, Zhang J, et al. Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer. Redox Biology. 53: 102318. PMID 35525024 DOI: 10.1016/j.redox.2022.102318  0.118
2023 Boyle TA, Bossler AD. RNA sequencing steps toward the first line. Cancer. PMID 37096746 DOI: 10.1002/cncr.34801  0.115
2021 Stence AA, Thomason JG, Pruessner JA, Sompallae RR, Snow AN, Ma D, Moore SA, Bossler AD. Validation of Optical Genome Mapping for the Molecular Diagnosis of Facioscapulohumeral Muscular Dystrophy (FSHD). The Journal of Molecular Diagnostics : Jmd. PMID 34384893 DOI: 10.1016/j.jmoldx.2021.07.021  0.111
2020 Abukhiran I, Lora GB, Kirby P, Shelton J, Shilyanski J, Wilson S, Bossler A, Sato Y, Bashir A, Sato M. RARE-13. INFLAMMATORY MYOFIBROBLASTIC TUMOR MIMICKING DESMOPLASTIC INFANTILE GANGLIOGLIOMA (DIG) OF THE TEMPORAL LOBE Neuro-Oncology. 22: iii444-iii444. DOI: 10.1093/neuonc/noaa222.724  0.102
2020 Dong Q, Xiu Y, Bossler A, Syrbu S, Wang H, Xue W, Zhao J, Li Q, Jin M, Wang L, Boyce B, Sakr H, Ansari MQ, Zhao C. CLL dedifferentiation to clonally related myeloid cells. Blood Advances. 4: 6169-6174. PMID 33351112 DOI: 10.1182/bloodadvances.2020002726  0.087
2024 Broeckel U, Iqbal MA, Levy B, Sahajpal N, Nagy PL, Scharer G, Rodriguez V, Bossler A, Stence A, Skinner C, Skinner SA, Kolhe R, Stevenson R. Detection of Constitutional Structural Variants by Optical Genome Mapping: A Multisite Study of Postnatal Samples. The Journal of Molecular Diagnostics : Jmd. PMID 38211722 DOI: 10.1016/j.jmoldx.2023.12.003  0.087
2021 Sabree SA, Lemke-Miltner CD, Blackwell SE, Yin C, Bossler A, Ebeid K, Salem AK, Weiner GJ. Monocytes Exposed to Immune Complexes Reduce pDC Type 1 Interferon Response to Vidutolimod. Vaccines. 9. PMID 34579220 DOI: 10.3390/vaccines9090982  0.077
2020 Carnahan RM, Waitman LR, Charlton ME, Schroeder MC, Bossler AD, Campbell WS, Campbell JR, McDowell BD, Smith NC, Gryzlak BM, Chrischilles EA. Exploration of PCORnet Data Resources for Assessing Use of Molecular-Guided Cancer Treatment. Jco Clinical Cancer Informatics. 4: 724-735. PMID 32795185 DOI: 10.1200/CCI.19.00142  0.072
2020 Rieken A, Bossler AD, Mathews KD, Moore SA. CLIA Laboratory Testing for Facioscapulohumeral Dystrophy (FSHD): A Retrospective Analysis. Neurology. PMID 33443126 DOI: 10.1212/WNL.0000000000011412  0.069
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