Brian J. Tunquist, Ph.D. - Publications

Affiliations: 
2003 University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Pharmacology, Molecular Biology, Cell Biology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Hernández-García S, San-Segundo L, González-Méndez L, Corchete LA, Misiewicz-Krzeminska I, Martín-Sánchez M, López-Iglesias AA, Algarín EM, Mogollón P, Díaz-Tejedor A, Paíno T, Tunquist B, Mateos MV, Gutiérrez NC, Díaz-Rodriguez E, et al. The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma. Haematologica. PMID 28860344 DOI: 10.3324/haematol.2017.168666  0.422
2016 Ocio EM, Motlló C, Rodriguez-Otero P, Martínez-López J, Rubia JDL, Ptaszynski M, Tunquist B, Garcia-Sanz R, Oriol A, Lahuerta JJ, San-Miguel J, Mateos M. Safety and Efficacy of Filanesib in Combination with Pomalidomide and Dexamethasone in Refractory MM Patients. Phase Ib/II Pomdefil Clinical Trial Conducted By the Spanish MM Group Blood. 128: 4503-4503. DOI: 10.1182/Blood.V128.22.4503.4503  0.304
2015 Whiting JL, Nygren PJ, Tunquist BJ, Langeberg LK, Seternes OM, Scott JD. Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220. The Journal of Biological Chemistry. 290: 19445-57. PMID 26088133 DOI: 10.1074/jbc.M115.654822  0.33
2015 Hernández-García S, González-Méndez L, Misiewicz-Krzeminska I, Algarín EM, López-Iglesias AA, San-Segundo L, Martín-Sánchez M, Paíno T, Gutierrez NC, Garayoa M, Tunquist B, Mateos M, Ocio EM. Filanesib Primarily Initiates the Apoptotic Program By Activating Bax through a Calpain-Dependent Mechanism Blood. 126: 5353-5353. DOI: 10.1182/BLOOD.V126.23.5353.5353  0.334
2015 Hernández-García S, San-Segundo L, González-Méndez L, Martín-Sánchez M, Corchete LA, Paíno T, López-Iglesias AA, Algarín EM, Garayoa M, Tunquist B, Gutierrez NC, Mateos M, Ocio EM. Mechanisms Underlying the Synergistic Interaction of Filanesib with Pomalidomide and Dexamethasone (FPD) in Multiple Myeloma Blood. 126: 1801-1801. DOI: 10.1182/Blood.V126.23.1801.1801  0.457
2015 Hernández-García S, San-Segundo L, González-Méndez L, Paíno T, López-Iglesias A, Martín-Sánchez M, Algarín E, Garayoa M, Humphries M, Tunquist B, San-Miguel J, Mateos M, Ocio E. Filanesib (ARRY-520) Demonstrates Potent and Rapid Activity in Preclinical Models of MM, Dependent on Bcl-2 Family Expression, and Synergistic with Dexamethasone and IMiDs Clinical Lymphoma Myeloma and Leukemia. 15: e213-e214. DOI: 10.1182/Blood.V124.21.4710.4710  0.467
2013 Humphries MJ, Anderson D, Williams L, Rieger R, Tunquist B, Walker D. ARRY-520 Combined With Pomalidomide Displays Enhanced Anti-Tumor Activity In Preclinical Models Of Multiple Myeloma Blood. 122: 3167-3167. DOI: 10.1182/Blood.V122.21.3167.3167  0.381
2012 Tunquist B, Brown K, Hingorani G, Lonial S, Kaufman JL, Zonder JA, Cohen AD, Bensinger WI, Orlowski RZ, Shah JJ, Hilder B, Ptaszynski AM, Koch K, Litwiler K, Walker D. Identification of Alpha 1-Acid Glycoprotein (AAG) As a Potential Patient Selection Biomarker for Improved Clinical Activity of the Novel KSP Inhibitor ARRY-520 in Relapsed and Refractory Multiple Myeloma (MM) Blood. 120: 1868-1868. DOI: 10.1182/Blood.V120.21.1868.1868  0.337
2011 Logue JS, Whiting JL, Tunquist B, Sacks DB, Langeberg LK, Wordeman L, Scott JD. AKAP220 protein organizes signaling elements that impact cell migration. The Journal of Biological Chemistry. 286: 39269-81. PMID 21890631 DOI: 10.1074/Jbc.M111.277756  0.365
2011 Logue JS, Whiting JL, Tunquist B, Langeberg LK, Scott JD. Anchored protein kinase A recruitment of active Rac GTPase. The Journal of Biological Chemistry. 286: 22113-21. PMID 21460214 DOI: 10.1074/jbc.M111.232660  0.456
2011 Woessner R, Tunquist B, Walker D, Rana S, Orlowski R, Kuhn D. Abstract 2550: Combination of the KSP inhibitor ARRY-520 with bortezomib causes sustained tumor regressions and significantly increased time to regrowth in bortezomib sensitive and resistant models of multiple myeloma Cancer Research. 71: 2550-2550. DOI: 10.1158/1538-7445.Am2011-2550  0.388
2010 Tunquist BJ, Woessner RD, Walker DH. Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520. Molecular Cancer Therapeutics. 9: 2046-56. PMID 20571074 DOI: 10.1158/1535-7163.Mct-10-0033  0.471
2010 Tunquist B, Risom T, Anderson D, Garrus J, Winski S, Wallace E, Winkler J, Koch K, Lee P, Walker D, Gross S. Abstract 3855: Investigation of the growth inhibitory activity of the MEK inhibitor ARRY-438162 in combination with everolimus in a variety of KRas and PI3K pathway mutant cancers Cancer Research. 70: 3855-3855. DOI: 10.1158/1538-7445.Am10-3855  0.407
2009 Woessner R, Tunquist B, Cox A, Rana S, Walker D, Lee PA. Combination of the KSP Inhibitor ARRY-520 with Bortezomib or Revlimid Causes Sustained Tumor Regressions and Significantly Increased Time to Regrowth in Models of Multiple Myeloma. Blood. 114: 2858-2858. DOI: 10.1182/Blood.V114.22.2858.2858  0.321
2003 Tunquist BJ, Eyers PA, Chen LG, Lewellyn AL, Maller JL. Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor-mediated metaphase arrest. The Journal of Cell Biology. 163: 1231-42. PMID 14691134 DOI: 10.1083/Jcb.200306153  0.662
2003 Ionov Y, Le X, Tunquist BJ, Sweetenham J, Sachs T, Ryder J, Johnson T, Lilly MB, Kraft AS. Pim-1 protein kinase is nuclear in Burkitt's lymphoma: nuclear localization is necessary for its biologic effects. Anticancer Research. 23: 167-78. PMID 12680209  0.315
2003 Tunquist BJ, Maller JL. Under arrest: cytostatic factor (CSF)-mediated metaphase arrest in vertebrate eggs. Genes & Development. 17: 683-710. PMID 12651887 DOI: 10.1101/Gad.1071303  0.583
2002 Tunquist BJ, Schwab MS, Chen LG, Maller JL. The spindle checkpoint kinase bub1 and cyclin e/cdk2 both contribute to the establishment of meiotic metaphase arrest by cytostatic factor. Current Biology : Cb. 12: 1027-33. PMID 12123578 DOI: 10.1016/S0960-9822(02)00894-1  0.667
2002 Maller JL, Schwab MS, Gross SD, Taieb FE, Roberts BT, Tunquist BJ. The mechanism of CSF arrest in vertebrate oocytes. Molecular and Cellular Endocrinology. 187: 173-8. PMID 11988325 DOI: 10.1016/S0303-7207(01)00695-5  0.691
2001 Maller JL, Schwab MS, Roberts BT, Gross SD, Taieb FE, Tunquist BJ. The pathway of MAP kinase mediation of CSF arrest in Xenopus oocytes. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 93: 27-33. PMID 11730319 DOI: 10.1016/S0248-4900(01)01127-3  0.685
2001 Schwab MS, Roberts BT, Gross SD, Tunquist BJ, Taieb FE, Lewellyn AL, Maller JL. Bub1 is activated by the protein kinase p90(Rsk) during Xenopus oocyte maturation. Current Biology : Cb. 11: 141-50. PMID 11231148 DOI: 10.1016/S0960-9822(01)00045-8  0.675
Show low-probability matches.