Edward K. Lobenhofer, Ph.D. - Publications

2000 Duke University, Durham, NC 
Molecular Biology, Pathology

30/46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Wurz RP, Pettus LH, Ashton K, Brown J, Chen JJ, Herberich B, Hong FT, Hu-Harrington E, Nguyen T, St Jean DJ, Tadesse S, Bauer D, Kubryk M, Zhan J, Cooke K, ... ... Lobenhofer EK, et al. Oxopyrido[2,3-d]pyrimidines as Covalent L858R/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors. Acs Medicinal Chemistry Letters. 6: 987-92. PMID 26396685 DOI: 10.1021/acsmedchemlett.5b00193  0.32
2010 Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ, Su Z, Chu TM, Goodsaid FM, Pusztai L, Shaughnessy JD, Oberthuer A, Thomas RS, Paules RS, Fielden M, ... ... Lobenhofer EK, et al. The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nature Biotechnology. 28: 827-38. PMID 20676074 DOI: 10.1038/nbt.1665  0.32
2010 Fan X, Lobenhofer EK, Chen M, Shi W, Huang J, Luo J, Zhang J, Walker SJ, Chu TM, Li L, Wolfinger R, Bao W, Paules RS, Bushel PR, Li J, et al. Consistency of predictive signature genes and classifiers generated using different microarray platforms. The Pharmacogenomics Journal. 10: 247-57. PMID 20676064 DOI: 10.1038/tpj.2010.34  0.32
2010 Alexeyenko A, Wassenberg DM, Lobenhofer EK, Yen J, Linney E, Sonnhammer EL, Meyer JN. Dynamic zebrafish interactome reveals transcriptional mechanisms of dioxin toxicity. Plos One. 5: e10465. PMID 20463971 DOI: 10.1371/journal.pone.0010465  0.32
2010 Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Molecular and Cellular Biology. 30: 1866-77. PMID 20123965 DOI: 10.1128/MCB.01060-09  0.32
2009 Nehmé A, Lobenhofer EK, Stamer WD, Edelman JL. Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. Bmc Medical Genomics. 2: 58. PMID 19744340 DOI: 10.1186/1755-8794-2-58  0.32
2009 Jacobsen LB, Calvin SA, Lobenhofer EK. Transcriptional effects of transfection: The potential for misinterpretation of gene expression data generated from transiently transfected cells Biotechniques. 47: 617-624. PMID 19594446 DOI: 10.2144/000113132  0.32
2009 Demircan B, Dyer LM, Gerace M, Lobenhofer EK, Robertson KD, Brown KD. Comparative epigenomics of human and mouse mammary tumors. Genes, Chromosomes & Cancer. 48: 83-97. PMID 18836996 DOI: 10.1002/gcc.20620  0.32
2008 Craft AM, Krisky DM, Wechuck JB, Lobenhofer EK, Jiang Y, Wolfe DP, Glorioso JC. Herpes simplex virus-mediated expression of Pax3 and MyoD in embryoid bodies results in lineage-Related alterations in gene expression profiles. Stem Cells (Dayton, Ohio). 26: 3119-29. PMID 18787207 DOI: 10.1634/stemcells.2008-0417  0.32
2008 Lobenhofer EK, Auman JT, Blackshear PE, Boorman GA, Bushel PR, Cunningham ML, Fostel JM, Gerrish K, Heinloth AN, Irwin RD, Malarkey DE, Merrick BA, Sieber SO, Tucker CJ, Ward SM, et al. Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype. Genome Biology. 9: R100. PMID 18570634 DOI: 10.1186/gb-2008-9-6-r100  0.32
2007 Beyer RP, Fry RC, Lasarev MR, McConnachie LA, Meira LB, Palmer VS, Powell CL, Ross PK, Bammler TK, Bradford BU, Cranson AB, Cunningham ML, Fannin RD, Higgins GM, Hurban P, ... ... Lobenhofer EK, et al. Multicenter study of acetaminophen hepatotoxicity reveals the importance of biological endpoints in genomic analyses. Toxicological Sciences : An Official Journal of the Society of Toxicology. 99: 326-37. PMID 17562736 DOI: 10.1093/toxsci/kfm150  0.32
2007 Zhou T, Chou J, Mullen TE, Elkon R, Zhou Y, Simpson DA, Bushel PR, Paules RS, Lobenhofer EK, Hurban P, Kaufmann WK. Identification of primary transcriptional regulation of cell cycle-regulated genes upon DNA damage. Cell Cycle (Georgetown, Tex.). 6: 972-81. PMID 17404513  0.32
2007 Newbold RR, Jefferson WN, Grissom SF, Padilla-Banks E, Snyder RJ, Lobenhofer EK. Developmental exposure to diethylstilbestrol alters uterine gene expression that may be associated with uterine neoplasia later in life. Molecular Carcinogenesis. 46: 783-96. PMID 17394237 DOI: 10.1002/mc.20308  0.32
2007 Mori K, Blackshear PE, Lobenhofer EK, Parker JS, Orzech DP, Roycroft JH, Walker KL, Johnson KA, Marsh TA, Irwin RD, Boorman GA. Hepatic transcript levels for genes coding for enzymes associated with xenobiotic metabolism are altered with age. Toxicologic Pathology. 35: 242-51. PMID 17366318 DOI: 10.1080/01926230601156286  0.32
2006 Lobenhofer EK, Boorman GA, Phillips KL, Heinloth AN, Malarkey DE, Blackshear PE, Houle C, Hurban P. Application of visualization tools to the analysis of histopathological data enhances biological insight and interpretation. Toxicologic Pathology. 34: 921-8. PMID 17178692 DOI: 10.1080/01926230601072319  0.32
2006 Guo L, Lobenhofer EK, Wang C, Shippy R, Harris SC, Zhang L, Mei N, Chen T, Herman D, Goodsaid FM, Hurban P, Phillips KL, Xu J, Deng X, Sun YA, et al. Rat toxicogenomic study reveals analytical consistency across microarray platforms. Nature Biotechnology. 24: 1162-9. PMID 17061323 DOI: 10.1038/nbt1238  0.32
2006 Cannon CH, Kua CS, Lobenhofer EK, Hurban P. Capturing genomic signatures of DNA sequence variation using a standard anonymous microarray platform. Nucleic Acids Research. 34: e121. PMID 17000641 DOI: 10.1093/nar/gkl478  0.32
2006 Shi L, Reid LH, Jones WD, Shippy R, Warrington JA, Baker SC, Collins PJ, de Longueville F, Kawasaki ES, Lee KY, Luo Y, Sun YA, Willey JC, Setterquist RA, ... ... Lobenhofer EK, et al. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nature Biotechnology. 24: 1151-61. PMID 16964229 DOI: 10.1038/nbt1239  0.32
2006 Patterson TA, Lobenhofer EK, Fulmer-Smentek SB, Collins PJ, Chu TM, Bao W, Fang H, Kawasaki ES, Hager J, Tikhonova IR, Walker SJ, Zhang L, Hurban P, de Longueville F, Fuscoe JC, et al. Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project. Nature Biotechnology. 24: 1140-50. PMID 16964228 DOI: 10.1038/nbt1242  0.32
2006 Zhou T, Chou JW, Simpson DA, Zhou Y, Mullen TE, Medeiros M, Bushel PR, Paules RS, Yang X, Hurban P, Lobenhofer EK, Kaufmann WK. Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence. Environmental Health Perspectives. 114: 553-9. PMID 16581545 DOI: 10.1289/ehp.8026  0.32
2005 Powell CL, Kosyk O, Bradford BU, Parker JS, Lobenhofer EK, Denda A, Uematsu F, Nakae D, Rusyn I. Temporal correlation of pathology and DNA damage with gene expression in a choline-deficient model of rat liver injury. Hepatology (Baltimore, Md.). 42: 1137-47. PMID 16250055 DOI: 10.1002/hep.20910  0.32
2005 Bammler T, Beyer RP, Bhattacharya S, Boorman GA, Boyles A, Bradford BU, Bumgarner RE, Bushel PR, Chaturvedi K, Choi D, Cunningham ML, Deng S, Dressman HK, Fannin RD, Farin FM, ... ... Lobenhofer EK, et al. Standardizing global gene expression analysis between laboratories and across platforms. Nature Methods. 2: 351-6. PMID 15846362 DOI: 10.1038/nmeth754  0.32
2004 Barad O, Meiri E, Avniel A, Aharonov R, Barzilai A, Bentwich I, Einav U, Gilad S, Hurban P, Karov Y, Lobenhofer EK, Sharon E, Shiboleth YM, Shtutman M, Bentwich Z, et al. MicroRNA expression detected by oligonucleotide microarrays: system establishment and expression profiling in human tissues. Genome Research. 14: 2486-94. PMID 15574827 DOI: 10.1101/gr.2845604  0.32
2004 Lobenhofer EK, Cui X, Bennett L, Cable PL, Merrick BA, Churchill GA, Afshari CA. Exploration of low-dose estrogen effects: Identification of No Observed Transcriptional Effect Level (NOTEL) Toxicologic Pathology. 32: 482-492. PMID 15223774 DOI: 10.1080/01926230490483324  0.32
2003 Peddada SD, Lobenhofer EK, Li L, Afshari CA, Weinberg CR, Umbach DM. Gene selection and clustering for time-course and dose-response microarray experiments using order-restricted inference. Bioinformatics (Oxford, England). 19: 834-41. PMID 12724293 DOI: 10.1093/bioinformatics/btg093  0.32
2003 Hodges LC, Cook JD, Lobenhofer EK, Li L, Bennett L, Bushel PR, Aldaz CM, Afshari CA, Walker CL. Tamoxifen functions as a molecular agonist inducing cell cycle-associated genes in breast cancer cells. Molecular Cancer Research : McR. 1: 300-11. PMID 12612058  0.32
2002 Gilliam LK, Lobenhofer EK, Greer PK, Scearce RM, Cirisano FD, Marks JR, Hale LP. BRCA2 monoclonal antibodies react with differentiating epithelium. Hybridoma and Hybridomics. 21: 261-9. PMID 12193279 DOI: 10.1089/153685902760213877  0.32
2001 Havrilesky LJ, McMahon CP, Lobenhofer EK, Whitaker R, Marks JR, Berchuck A. Relationship between expression of coactivators and corepressors of hormone receptors and resistance of ovarian cancers to growth regulation by steroid hormones. Journal of the Society For Gynecologic Investigation. 8: 104-13. PMID 11336882 DOI: 10.1016/S1071-5576(01)00093-4  0.32
2000 Lobenhofer EK, Marks JR. Estrogen-induced mitogenesis of MCF-7 cells does not require the induction of mitogen-activated protein kinase activity. The Journal of Steroid Biochemistry and Molecular Biology. 75: 11-20. PMID 11179904 DOI: 10.1016/S0960-0760(00)00132-1  0.32
2000 Lobenhofer EK, Huper G, Iglehart JD, Marks JR. Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 11: 99-110. PMID 10714766  0.32
Low-probability matches
2020 Giffin MJ, Cooke K, Lobenhofer EK, Estrada JC, Zhan J, Deegen P, Thomas M, Murawsky CM, Werner J, Liu S, Lee F, Homann O, Friedrich M, Pearson JT, Raum T, et al. AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small Cell Lung Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33203642 DOI: 10.1158/1078-0432.CCR-20-2845  0.01
2020 Lafleur MA, Werner J, Fort M, Lobenhofer EK, Balazs M, Goyos A. MRGPRX2 activation as a rapid, high-throughput mechanistic-based approach for detecting peptide-mediated human mast cell degranulation liabilities. Journal of Immunotoxicology. 17: 110-121. PMID 32525431 DOI: 10.1080/1547691X.2020.1757793  0.01
2019 Lobenhofer E, Werner J, Giffin M, Engwall M, Davies R, Homann O, Lafleur M, Moffat G. P1.12-18 Nonclinical Safety Assessment of AMG 757, a DLL3 Bispecific T Cell Engager, in the Cynomolgus Monkey Journal of Thoracic Oncology. 14: S541. DOI: 10.1016/j.jtho.2019.08.1131  0.01
2018 Giffin M, Cooke K, Lobenhofer E, Friedrich M, Raum T, Coxon A. P3.12-03 Targeting DLL3 with AMG 757, a BiTE® Antibody Construct, and AMG 119, a CAR-T, for the Treatment of SCLC Journal of Thoracic Oncology. 13: S971. DOI: 10.1016/J.JTHO.2018.08.1826  0.01
2010 Mei N, Fuscoe JC, Lobenhofer EK, Guo L. Application of microarray-based analysis of gene expression in the field of toxicogenomics. Methods in Molecular Biology (Clifton, N.J.). 597: 227-41. PMID 20013237 DOI: 10.1007/978-1-60327-389-3_16  0.01
2009 Trick M, Cheung F, Drou N, Fraser F, Lobenhofer EK, Hurban P, Magusin A, Town CD, Bancroft I. A newly-developed community microarray resource for transcriptome profiling in Brassica species enables the confirmation of Brassica-specific expressed sequences. Bmc Plant Biology. 9: 50. PMID 19426481 DOI: 10.1186/1471-2229-9-50  0.01
2006 Gaillard S, Grasfeder LL, Haeffele CL, Lobenhofer EK, Chu TM, Wolfinger R, Kazmin D, Koves TR, Muoio DM, Chang CY, McDonnell DP. Receptor-selective coactivators as tools to define the biology of specific receptor-coactivator pairs. Molecular Cell. 24: 797-803. PMID 17157261 DOI: 10.1016/j.molcel.2006.10.012  0.01
2006 Santen RJ, Lobenhofer EK, Afshari CA, Bao Y, Song RX. Adaptation of estrogen-regulated genes in long-term estradiol deprived MCF-7 breast cancer cells. Breast Cancer Research and Treatment. 94: 213-23. PMID 16258703 DOI: 10.1007/s10549-005-5776-4  0.01
2005 Boorman GA, Blackshear PE, Parker JS, Lobenhofer EK, Malarkey DE, Vallant MK, Gerken DK, Irwin RD. Hepatic gene expression changes throughout the day in the Fischer rat: implications for toxicogenomic experiments. Toxicological Sciences : An Official Journal of the Society of Toxicology. 86: 185-93. PMID 15814895 DOI: 10.1093/toxsci/kfi166  0.01
2005 Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA. Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen. Toxicologic Pathology. 33: 111-7. PMID 15805062 DOI: 10.1080/01926230590522257  0.01
2005 Boorman GA, Irwin RD, Vallant MK, Gerken DK, Lobenhofer EK, Hejtmancik MR, Hurban P, Brys AM, Travlos GS, Parker JS, Portier CJ. Variation in the hepatic gene expression in individual male Fischer rats. Toxicologic Pathology. 33: 102-10. PMID 15805061 DOI: 10.1080/01926230590522211  0.01
2005 Grissom SF, Lobenhofer EK, Tucker CJ. A qualitative assessment of direct-labeled cDNA products prior to microarray analysis. Bmc Genomics. 6: 36. PMID 15762992 DOI: 10.1186/1471-2164-6-36  0.01
2005 Bammler T, Beyer RP, Bhattacharya S, Boorman GA, Boyles A, Bradford BU, Bumgarner RE, Bushel PR, Chaturvedi K, Choi D, Cunningham ML, Deng S, Dressman HK, Fannin RD, Farin FM, ... ... Lobenhofer EK, et al. Addendum: Standardizing global gene expression analysis between laboratories and across platforms Nature Methods. 2: 477-477. DOI: 10.1038/nmeth0605-477a  0.01
2004 Jansen MS, Nagel SC, Miranda PJ, Lobenhofer EK, Afshari CA, McDonnell DP. Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition. Proceedings of the National Academy of Sciences of the United States of America. 101: 7199-204. PMID 15103026 DOI: 10.1073/pnas.0402014101  0.01
2002 Lobenhofer EK, Bennett L, Cable PL, Li L, Bushel PR, Afshari CA. Regulation of DNA replication fork genes by 17beta-estradiol. Molecular Endocrinology (Baltimore, Md.). 16: 1215-29. PMID 12040010 DOI: 10.1210/mend.16.6.0858  0.01
2001 Lobenhofer EK, Bushel PR, Afshari CA, Hamadeh HK. Progress in the application of DNA microarrays. Environmental Health Perspectives. 109: 881-91. PMID 11673116  0.01
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