Nathaniel J. Szewczyk, Ph.D. - Publications

Affiliations: 
2002 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Cell Biology, Genetics

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Szewczyk NJ, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.44
2016 Bass JJ, Wilkinson DJ, Rankin D, Phillips BE, Szewczyk NJ, Smith K, Atherton PJ. An overview of technical considerations for Western blotting applications to physiological research. Scandinavian Journal of Medicine & Science in Sports. PMID 27263489 DOI: 10.1111/Sms.12702  0.44
2016 Mora-Lorca JA, Sáenz-Narciso B, Gaffney CJ, Naranjo-Galindo FJ, Pedrajas JR, Guerrero-Gómez D, Dobrzynska A, Askjaer P, Szewczyk NJ, Cabello J, Miranda-Vizuete A. Glutathione reductase gsr-1 is an essential gene required for Caenorhabditis elegans early embryonic development. Free Radical Biology & Medicine. PMID 27117030 DOI: 10.1016/J.Freeradbiomed.2016.04.017  0.44
2016 Gaffney CJ, Shephard F, Chu J, Baillie DL, Rose A, Constantin-Teodosiu D, Greenhaff PL, Szewczyk NJ. Degenerin channel activation causes caspase-mediated protein degradation and mitochondrial dysfunction in adult C.elegans muscle Journal of Cachexia, Sarcopenia and Muscle. 7: 181-192. DOI: 10.1002/jcsm.12040  0.44
2015 Brook MS, Wilkinson DJ, Mitchell WK, Lund JN, Szewczyk NJ, Greenhaff PL, Smith K, Atherton PJ. Skeletal muscle hypertrophy adaptations predominate in the early stages of resistance exercise training, matching deuterium oxide-derived measures of muscle protein synthesis and mechanistic target of rapamycin complex 1 signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 4485-96. PMID 26169934 DOI: 10.1096/Fj.15-273755  0.44
2015 Etheridge T, Rahman M, Gaffney CJ, Shaw D, Shephard F, Magudia J, Solomon DE, Milne T, Blawzdziewicz J, Constantin-Teodosiu D, Greenhaff PL, Vanapalli SA, Szewczyk NJ. The integrin-adhesome is required to maintain muscle structure, mitochondrial ATP production, and movement forces in Caenorhabditis elegans. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1235-46. PMID 25491313 DOI: 10.1096/Fj.14-259119  0.44
2014 Gaffney CJ, Bass JJ, Barratt TF, Szewczyk NJ. Methods to assess subcellular compartments of muscle in C. elegans. Journal of Visualized Experiments : Jove. e52043. PMID 25489753 DOI: 10.3791/52043  0.44
2014 Estevez AO, Morgan KL, Szewczyk NJ, Gems D, Estevez M. The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans. Neurotoxicology. 41: 28-43. PMID 24406377 DOI: 10.1016/J.Neuro.2013.12.012  0.44
2014 Wilkinson DJ, Franchi MV, Brook MS, Narici MV, Williams JP, Mitchell WK, Szewczyk NJ, Greenhaff PL, Atherton PJ, Smith K. A validation of the application of D(2)O stable isotope tracer techniques for monitoring day-to-day changes in muscle protein subfraction synthesis in humans. American Journal of Physiology. Endocrinology and Metabolism. 306: E571-9. PMID 24381002 DOI: 10.1152/Ajpendo.00650.2013  0.44
2014 Muñoz-Lobato F, Rodríguez-Palero MJ, Naranjo-Galindo FJ, Shephard F, Gaffney CJ, Szewczyk NJ, Hamamichi S, Caldwell KA, Caldwell GA, Link CD, Miranda-Vizuete A. Protective role of DNJ-27/ERdj5 in Caenorhabditis elegans models of human neurodegenerative diseases. Antioxidants & Redox Signaling. 20: 217-35. PMID 23641861 DOI: 10.1089/Ars.2012.5051  0.44
2013 Lehmann S, Bass JJ, Szewczyk NJ. Knockdown of the C. elegans kinome identifies kinases required for normal protein homeostasis, mitochondrial network structure, and sarcomere structure in muscle. Cell Communication and Signaling : Ccs. 11: 71. PMID 24060339 DOI: 10.1186/1478-811X-11-71  0.44
2013 Warren P, Golden A, Hanover J, Love D, Shephard F, Szewczyk NJ. Evaluation of the Fluids Mixing Enclosure System for Life Science Experiments During a Commercial Caenorhabditis elegans Spaceflight Experiment. Advances in Space Research : the Official Journal of the Committee On Space Research (Cospar). 51: 2241-2250. PMID 23794777 DOI: 10.1016/J.Asr.2013.02.002  0.44
2013 Crossland H, Kazi AA, Lang CH, Timmons JA, Pierre P, Wilkinson DJ, Smith K, Szewczyk NJ, Atherton PJ. Focal adhesion kinase is required for IGF-I-mediated growth of skeletal muscle cells via a TSC2/mTOR/S6K1-associated pathway. American Journal of Physiology. Endocrinology and Metabolism. 305: E183-93. PMID 23695213 DOI: 10.1152/Ajpendo.00541.2012  0.44
2013 Wilkinson DJ, Hossain T, Hill DS, Phillips BE, Crossland H, Williams J, Loughna P, Churchward-Venne TA, Breen L, Phillips SM, Etheridge T, Rathmacher JA, Smith K, Szewczyk NJ, Atherton PJ. Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism Journal of Physiology. 591: 2911-2923. PMID 23551944 DOI: 10.1113/Jphysiol.2013.253203  0.44
2012 Lehmann S, Shephard F, Jacobson LA, Szewczyk NJ. Integrated control of protein degradation in C. elegans muscle. Worm. 1: 141-50. PMID 23457662 DOI: 10.4161/worm.20465  0.44
2012 Lehmann S, Shephard F, Jacobson LA, Szewczyk NJ. Using Multiple Phenotype Assays and Epistasis Testing to Enhance the Reliability of RNAi Screening and Identify Regulators of Muscle Protein Degradation. Genes. 3: 686-701. PMID 23152949 DOI: 10.3390/Genes3040686  0.44
2012 Honda Y, Higashibata A, Matsunaga Y, Yonezawa Y, Kawano T, Higashitani A, Kuriyama K, Shimazu T, Tanaka M, Szewczyk NJ, Ishioka N, Honda S. Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans. Scientific Reports. 2: 487. PMID 22768380 DOI: 10.1038/Srep00487  0.44
2012 Estevez AO, Mueller CL, Morgan KL, Szewczyk NJ, Teece L, Miranda-Vizuete A, Estevez M. Selenium induces cholinergic motor neuron degeneration in Caenorhabditis elegans. Neurotoxicology. 33: 1021-32. PMID 22560997 DOI: 10.1016/J.Neuro.2012.04.019  0.44
2012 Etheridge T, Oczypok EA, Lehmann S, Fields BD, Shephard F, Jacobson LA, Szewczyk NJ. Calpains mediate integrin attachment complex maintenance of adult muscle in Caenorhabditis elegans. Plos Genetics. 8: e1002471. PMID 22253611 DOI: 10.1371/Journal.Pgen.1002471  0.44
2012 Oczypok EA, Etheridge T, Freeman J, Stodieck L, Johnsen R, Baillie D, Szewczyk NJ. Remote automated multi-generational growth and observation of an animal in low Earth orbit. Journal of the Royal Society, Interface / the Royal Society. 9: 596-9. PMID 22130552 DOI: 10.1098/Rsif.2011.0716  0.44
2011 Shephard F, Adenle AA, Jacobson LA, Szewczyk NJ. Identification and functional clustering of genes regulating muscle protein degradation from amongst the known C. elegans muscle mutants. Plos One. 6: e24686. PMID 21980350 DOI: 10.1371/Journal.Pone.0024686  0.44
2010 Morgan KL, Estevez AO, Mueller CL, Cacho-Valadez B, Miranda-Vizuete A, Szewczyk NJ, Estevez M. The glutaredoxin GLRX-21 functions to prevent selenium-induced oxidative stress in Caenorhabditis elegans. Toxicological Sciences : An Official Journal of the Society of Toxicology. 118: 530-43. PMID 20833709 DOI: 10.1093/Toxsci/Kfq273  0.44
2009 Adenle AA, Johnsen B, Szewczyk NJ. Review of the results from the International C. elegans first experiment (ICE-FIRST). Advances in Space Research : the Official Journal of the Committee On Space Research (Cospar). 44: 210-216. PMID 20161164 DOI: 10.1016/J.Asr.2009.04.008  0.44
2008 Selch F, Higashibata A, Imamizo-Sato M, Higashitani A, Ishioka N, Szewczyk NJ, Conley CA. Genomic response of the nematode Caenorhabditis elegans to spaceflight. Advances in Space Research : the Official Journal of the Committee On Space Research (Cospar). 41: 807-815. PMID 18392117 DOI: 10.1016/J.Asr.2007.11.015  0.44
2008 Szewczyk NJ, Tillman J, Conley CA, Granger L, Segalat L, Higashitani A, Honda S, Honda Y, Kagawa H, Adachi R, Higashibata A, Fujimoto N, Kuriyama K, Ishioka N, Fukui K, et al. Description of International Caenorhabditis elegans Experiment first flight (ICE-FIRST) Advances in Space Research. 42: 1072-1079. DOI: 10.1016/j.asr.2008.03.017  0.44
2007 Higashibata A, Higashitani A, Adachi R, Kagawa H, Honda S, Honda Y, Higashitani N, Sasagawa Y, Miyazawa Y, Szewczyk NJ, Conley CA, Fujimoto N, Fukui K, Shimazu T, Kuriyama K, et al. Biochemical and Molecular Biological Analyses of space-flown nematodes in Japan, the First International Caenorhabditis elegans Experiment (ICE-First). Microgravity Science and Technology. 19: 159-163. PMID 19513185 DOI: 10.1007/Bf02919473  0.44
2007 Leandro LJ, Szewczyk NJ, Benguría A, Herranz R, Laván D, Medina FJ, Gasset G, Loon JV, Conley CA, Marco R. Comparative analysis of Drosophila melanogaster and Caenorhabditis elegans gene expression experiments in the European Soyuz flights to the International Space Station. Advances in Space Research : the Official Journal of the Committee On Space Research (Cospar). 40: 506-512. PMID 18084631 DOI: 10.1016/J.Asr.2007.05.070  0.44
2007 Stevenson TO, Mercer KB, Cox EA, Szewczyk NJ, Conley CA, Hardin JD, Benian GM. unc-94 encodes a tropomodulin in Caenorhabditis elegans. Journal of Molecular Biology. 374: 936-50. PMID 17976644 DOI: 10.1016/J.Jmb.2007.10.005  0.44
2007 Szewczyk NJ, Peterson BK, Barmada SJ, Parkinson LP, Jacobson LA. Opposed growth factor signals control protein degradation in muscles of Caenorhabditis elegans. The Embo Journal. 26: 935-43. PMID 17290229 DOI: 10.1038/Sj.Emboj.7601540  0.44
2006 Szewczyk NJ, Udranszky IA, Kozak E, Sunga J, Kim SK, Jacobson LA, Conley CA. Delayed development and lifespan extension as features of metabolic lifestyle alteration in C. elegans under dietary restriction. The Journal of Experimental Biology. 209: 4129-39. PMID 17023606 DOI: 10.1242/Jeb.02492  0.44
2006 Higashibata A, Szewczyk NJ, Conley CA, Imamizo-Sato M, Higashitani A, Ishioka N. Decreased expression of myogenic transcription factors and myosin heavy chains in Caenorhabditis elegans muscles developed during spaceflight. The Journal of Experimental Biology. 209: 3209-18. PMID 16888068 DOI: 10.1242/Jeb.02365  0.44
2005 Szewczyk NJ, Mancinelli RL, McLamb W, Reed D, Blumberg BS, Conley CA. Caenorhabditis elegans survives atmospheric breakup of STS-107, space shuttle Columbia. Astrobiology. 5: 690-705. PMID 16379525 DOI: 10.1089/Ast.2005.5.690  0.44
2005 Szewczyk NJ, Jacobson LA. Signal-transduction networks and the regulation of muscle protein degradation. The International Journal of Biochemistry & Cell Biology. 37: 1997-2011. PMID 16125109 DOI: 10.1016/J.Biocel.2005.02.020  0.44
2003 Szewczyk NJ, Kozak E, Conley CA. Chemically defined medium and Caenorhabditis elegans. Bmc Biotechnology. 3: 19. PMID 14580264 DOI: 10.1186/1472-6750-3-19  0.44
2003 Szewczyk NJ, Jacobson LA. Activated EGL-15 FGF receptor promotes protein degradation in muscles of Caenorhabditis elegans. The Embo Journal. 22: 5058-67. PMID 14517244 DOI: 10.1093/Emboj/Cdg472  0.44
2002 Szewczyk NJ, Peterson BK, Jacobson LA. Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans. Molecular and Cellular Biology. 22: 4181-8. PMID 12024031 DOI: 10.1128/Mcb.22.12.4181-4188.2002  0.44
2000 Szewczyk NJ, Hartman JJ, Barmada SJ, Jacobson LA. Genetic defects in acetylcholine signalling promote protein degradation in muscle cells of Caenorhabditis elegans. Journal of Cell Science. 113: 2003-10. PMID 10806111  0.44
1997 Zdinak LA, Greenberg IB, Szewczyk NJ, Barmada SJ, Cardamone-Rayner M, Hartman JJ, Jacobson LA. Transgene-coded chimeric proteins as reporters of intracellular proteolysis: starvation-induced catabolism of a lacZ fusion protein in muscle cells of Caenorhabditis elegans. Journal of Cellular Biochemistry. 67: 143-53. PMID 9328848 DOI: 10.1002/(Sici)1097-4644(19971001)67:1<143::Aid-Jcb15>3.0.Co;2-I  0.44
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