William E. Louch, Ph.D. - Publications

2001 Dalhousie University, Halifax, Nova Scotia, Canada 
Pharmacology, Cell Biology, Animal Physiology Biology

105 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TR, Dalhus B, Subramanian H, Hille S, Christensen G, Müller OJ, ... ... Louch WE, et al. AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR. Circulation Research. PMID 34814703 DOI: 10.1161/CIRCRESAHA.120.317976  1
2021 Setterberg IE, Le C, Frisk M, Perdreau-Dahl H, Li J, Louch WE. Corrigendum: The Physiology and Pathophysiology of T-Tubules in the Heart. Frontiers in Physiology. 12: 790227. PMID 34764889 DOI: 10.3389/fphys.2021.790227  1
2021 Edwards AG, Mørk H, Stokke MK, Lipsett DB, Sjaastad I, Richard S, Sejersted OM, Louch WE. Sarcoplasmic Reticulum Calcium Release Is Required for Arrhythmogenesis in the Mouse. Frontiers in Physiology. 12: 744730. PMID 34712150 DOI: 10.3389/fphys.2021.744730  1
2021 Kobirumaki-Shimozawa F, Shimozawa T, Oyama K, Baba S, Li J, Nakanishi T, Terui T, Louch WE, Ishiwata S, Fukuda N. Synchrony of sarcomeric movement regulates left ventricular pump function in the in vivo beating mouse heart. The Journal of General Physiology. 153. PMID 34605861 DOI: 10.1085/jgp.202012860  1
2021 Setterberg IE, Le C, Frisk M, Li J, Louch WE. The Physiology and Pathophysiology of T-Tubules in the Heart. Frontiers in Physiology. 12: 718404. PMID 34566684 DOI: 10.3389/fphys.2021.718404  1
2021 Grote Beverborg N, Später D, Knöll R, Hidalgo A, Yeh ST, Elbeck Z, Silljé HHW, Eijgenraam TR, Siga H, Zurek M, Palmér M, Pehrsson S, Albery T, Bomer N, Hoes MF, ... ... Louch WE, et al. Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy. Nature Communications. 12: 5180. PMID 34462437 DOI: 10.1038/s41467-021-25439-0  1
2021 Sadredini M, Haugsten Hansen M, Frisk M, Louch WE, Lehnart SE, Sjaastad I, Stokke MK. CaMKII inhibition has dual effects on spontaneous Ca release and Ca alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34270372 DOI: 10.1152/ajpheart.00011.2021  1
2021 Yamakawa S, Wu D, Dasgupta M, Pedamallu H, Gupta B, Modi R, Mufti M, O'Callaghan C, Frisk M, Louch WE, Arora R, Shiferaw Y, Burrell A, Ryan J, Nelson L, et al. Role of T-Tubule Remodeling on Mechanisms of Abnormal Calcium Release During Heart Failure Development in Canine Ventricle. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33635163 DOI: 10.1152/ajpheart.00946.2020  1
2021 Frisk M, Le C, Shen X, Røe ÅT, Hou Y, Manfra O, Silva GJJ, van Hout I, Norden ES, Aronsen JM, Laasmaa M, Espe EKS, Zouein FA, Lambert RR, Dahl CP, ... ... Louch WE, et al. Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction. Journal of the American College of Cardiology. 77: 405-419. PMID 33509397 DOI: 10.1016/j.jacc.2020.11.044  1
2020 Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK. Exercise Training Stabilizes RyR2-Dependent Ca Release in Post-infarction Heart Failure. Frontiers in Cardiovascular Medicine. 7: 623922. PMID 33569394 DOI: 10.3389/fcvm.2020.623922  1
2020 Foo KS, Lehtinen ML, Leung CY, Lian X, Xu J, Keung W, Geng L, Kolstad TRS, Thams S, Wong AO, Wong N, Bylund K, Zhou C, He X, Jin SB, ... ... Louch WE, et al. Human ISL1 Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33296664 DOI: 10.1016/j.ymthe.2020.11.015  1
2020 Louch WE. A horse of a different colour: distinct mechanisms of HFpEF and HFrEF. The Journal of Physiology. PMID 32985684 DOI: 10.1113/JP280691  0.01
2020 Masjoan Juncos JX, Shakil S, Bradley WE, Wei CC, Zafar I, Powell P, Mariappan N, Louch WE, Ford DA, Ahmad A, Dell'Italia LJ, Ahmad S. Chronic cardiac structural damage, diastolic and systolic dysfunction following acute myocardial injury due to bromine exposure in rats. Archives of Toxicology. PMID 32979061 DOI: 10.1007/s00204-020-02919-8  1
2020 Rubinstein J, Woo JG, Garcia AM, Alsaied T, Li J, Lunde PK, Moore RA, Laasmaa M, Sammons A, Mays WA, Miyamoto SD, Louch WE, Veldtman GR. Probenecid Improves Cardiac Function in Subjects with a Fontan Circulation and Augments Cardiomyocyte Calcium Homeostasis. Pediatric Cardiology. PMID 32770262 DOI: 10.1007/S00246-020-02427-7  1
2020 Altara R, da Silva GJJ, Frisk M, Spelta F, Zouein FA, Louch WE, Booz GW, Cataliotti A. Cardioprotective Effects of the Novel Compound Vastiras in a Preclinical Model of End-Organ Damage. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12014. PMID 32200677 DOI: 10.1161/Hypertensionaha.120.14704  1
2020 Kobirumaki-Shimozawa F, Nakanishi T, Shimozawa T, Terui T, Oyama K, Li J, Louch WE, Ishiwata S, Fukuda N. Real-Time In Vivo Imaging of Mouse Left Ventricle Reveals Fluctuating Movements of the Intercalated Discs. Nanomaterials (Basel, Switzerland). 10. PMID 32188039 DOI: 10.3390/nano10030532  0.01
2020 Tazmini K, Frisk M, Lewalle A, Laasmaa M, Morotti S, Lipsett DB, Manfra O, Skogestad J, Aronsen JM, Sejersted OM, Sjaastad I, Edwards AG, Grandi E, Niederer SA, Oie E, ... Louch WE, et al. Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes. Circulation Research. PMID 32070187 DOI: 10.1161/CIRCRESAHA.119.315641  1
2020 Tazmini K, Fraz MSA, Nymo SH, Stokke MK, Louch WE, Øie E. Potassium infusion increases the likelihood of conversion of recent-onset atrial fibrillation-A single-blinded, randomized clinical trial. American Heart Journal. 221: 114-124. PMID 31986288 DOI: 10.1016/j.ahj.2019.12.014  1
2019 Shiferaw Y, Aistrup GL, Louch WE, Wasserstrom JA. Remodeling Promotes Proarrhythmic Disruption of Calcium Homeostasis in Failing Atrial Myocytes. Biophysical Journal. PMID 31889516 DOI: 10.1016/J.Bpj.2019.12.012  0.01
2019 Laasmaa M, Lu P, Veletić M, Louch WE, Bergsland J, Balasingham I, Vendelin M. Energy-efficiency of Cardiomyocyte Stimulation with Rectangular Pulses. Scientific Reports. 9: 13307. PMID 31527628 DOI: 10.1038/s41598-019-49791-w  0.01
2019 Tazmini K, Nymo SH, Louch WE, Ranhoff AH, Øie E. Electrolyte imbalances in an unselected population in an emergency department: A retrospective cohort study. Plos One. 14: e0215673. PMID 31022222 DOI: 10.1371/journal.pone.0215673  1
2019 Colli DF, Blood SR, Sankarankutty AC, Sachse FB, Frisk M, Louch WE, Kekenes-Huskey PM. A Matched-Filter-Based Algorithm for Subcellular Classification of T-System in Cardiac Tissues. Biophysical Journal. PMID 30979553 DOI: 10.1016/J.Bpj.2019.03.010  1
2019 Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, ... ... Louch WE, et al. Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca-Dependent Arrhythmia. Circulation. Arrhythmia and Electrophysiology. 12: e007045. PMID 30943765 DOI: 10.1161/CIRCEP.118.007045  1
2019 Louch WE. Channel surfing: new insights into plasticity of excitation-contraction coupling. The Journal of Physiology. PMID 30854650 DOI: 10.1113/JP277783  0.01
2019 Goodridge JP, Jacobs B, Saetersmoen ML, Clement D, Hammer Q, Clancy T, Skarpen E, Brech A, Landskron J, Grimm C, Pfefferle A, Meza-Zepeda L, Lorenz S, Wiiger MT, Louch WE, et al. Remodeling of secretory lysosomes during education tunes functional potential in NK cells. Nature Communications. 10: 514. PMID 30705279 DOI: 10.1038/S41467-019-08384-X  0.01
2019 Skogestad J, Lines GT, Louch WE, Sejersted OM, Sjaastad I, Aronsen JM. Evidence for heterogeneous subsarcolemmal Na levels in rat ventricular myocytes. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30657726 DOI: 10.1152/ajpheart.00637.2018  1
2018 Jones PP, MacQuaide N, Louch WE. Dyadic Plasticity in Cardiomyocytes. Frontiers in Physiology. 9: 1773. PMID 30618792 DOI: 10.3389/fphys.2018.01773  0.01
2018 Shen X, Brink JVD, Hou Y, Colli D, Le C, Kolstad TR, MacQuaide N, Carlson CR, Kekenes-Huskey PM, Edwards AG, Soeller C, Louch WE. 3D dSTORM imaging reveals novel detail of ryanodine receptor localization in rat cardiac myocytes. The Journal of Physiology. PMID 30412283 DOI: 10.1113/Jp277360  1
2018 Gamage TH, Gunnes G, Lee RH, Louch WE, Holmgren A, Bruton JD, Lengle E, Kolstad TRS, Revold T, Amundsen SS, Dalen KT, Holme PA, Tjønnfjord GE, Christensen G, Westerblad H, et al. STIM1 R304W causes muscle degeneration and impaired platelet activation in mice. Cell Calcium. 76: 87-100. PMID 30390422 DOI: 10.1016/j.ceca.2018.10.001  1
2018 Ahmad S, Masjoan Juncos JX, Ahmad A, Zaky A, Wei CC, Bradley W, Zafar I, Powell P, Mariappan N, Vetal N, Louch WE, Ford DA, Doran S, Matalon S, Dell'Italia LJ. Bromine-inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30379573 DOI: 10.1152/Ajpheart.00652.2017  1
2018 Kolstad TR, van den Brink J, MacQuaide N, Lunde PK, Frisk M, Aronsen JM, Norden ES, Cataliotti A, Sjaastad I, Sejersted OM, Edwards AG, Lines GT, Louch WE. Ryanodine receptor dispersion disrupts Ca release in failing cardiac myocytes. Elife. 7. PMID 30375974 DOI: 10.7554/eLife.39427  1
2018 Ghali R, Altara R, Louch WE, Cataliotti A, Mallat Z, Kaplan A, Zouein FA, Booz GW. IL-33 (Interleukin 33)/sST2 (Soluble Suppression of Tumorigenicity 2) Axis in Hypertension and Heart Failure. Hypertension (Dallas, Tex. : 1979). 72: 818-828. PMID 30354724 DOI: 10.1161/Hypertensionaha.118.11157  1
2018 Røe ÅT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Sjaastad Nordén E, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Øystein Andersen G, Sjaastad I, ... Louch WE, et al. Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression. Cardiovascular Research. PMID 30351410 DOI: 10.1093/cvr/cvy257  1
2018 Foo KS, Lehtinen ML, Leung CY, Lian X, Xu J, Keung W, Geng L, Kolstad TRS, Thams S, Wong AO, Wong N, Bylund K, Zhou C, He X, Jin SB, ... ... Louch WE, et al. Human ISL1Ventricular Progenitors Self-Assemble into an In Vivo Functional Heart Patch and Preserve Cardiac Function Post Infarction. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 29606507 DOI: 10.1016/J.Ymthe.2018.02.012  1
2017 Parikh SS, Blackwell DJ, Gomez-Hurtado N, Frisk M, Wang L, Kim K, Dahl CP, Fiane AE, Tønnessen T, Kryshtal DO, Louch WE, Knollmann BC. Thyroid and Glucocorticoid Hormones Promote Functional T-tubule Development in Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes. Circulation Research. PMID 28974554 DOI: 10.1161/CIRCRESAHA.117.311920  1
2017 Gattoni S, Treu Røe Å, Aronsen JM, Sjaastad I, Louch WE, Smith NP, Niederer SA. Compensatory and decompensatory alterations in cardiomyocyte Ca(2+) dynamics in hearts with diastolic dysfunction following aortic banding. The Journal of Physiology. PMID 28542952 DOI: 10.1113/JP273879  1
2017 Louch WE, Nattel S. T-tubular collagen: a new player in mechanosensing and disease? Cardiovascular Research. PMID 28481973 DOI: 10.1093/Cvr/Cvx091  0.01
2017 Røe ÅT, Aronsen JM, Skårdal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE. Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy. Cardiovascular Research. PMID 28472418 DOI: 10.1093/cvr/cvx087  1
2017 Maleckar MM, Edwards AG, Louch WE, Lines GT. Studying dyadic structure-function relationships: a review of current modeling approaches and new insights into Ca(2+) (mis)handling. Clinical Medicine Insights. Cardiology. 11: 1179546817698602. PMID 28469494 DOI: 10.1177/1179546817698602  1
2017 Edwards AG, Louch WE. Species-Dependent Mechanisms of Cardiac Arrhythmia: A Cellular Focus. Clinical Medicine Insights. Cardiology. 11: 1179546816686061. PMID 28469490 DOI: 10.1177/1179546816686061  1
2017 Manfra O, Frisk M, Louch WE. Regulation of Cardiomyocyte T-Tubular Structure: Opportunities for Therapy. Current Heart Failure Reports. PMID 28447290 DOI: 10.1007/s11897-017-0329-9  1
2017 Ottesen AH, Carlson CR, Louch WE, Dahl MB, Sandbu RA, Johansen RF, Jarstadmarken H, Bjørås M, Høiseth AD, Brynildsen J, Sjaastad I, Stridsberg M, Omland T, Christensen G, Røsjø H. Glycosylated Chromogranin A in Heart Failure: Implications for Processing and Cardiomyocyte Calcium Homeostasis. Circulation. Heart Failure. 10. PMID 28209766 DOI: 10.1161/CIRCHEARTFAILURE.116.003675  1
2017 Olsen MB, Hildrestrand GA, Scheffler K, Vinge LE, Alfsnes K, Palibrk V, Wang J, Neurauter CG, Luna L, Johansen J, Øgaard JD, Ohm IK, Slupphaug G, Kuśnierczyk A, Fiane AE, ... ... Louch WE, et al. NEIL3-Dependent Regulation of Cardiac Fibroblast Proliferation Prevents Myocardial Rupture. Cell Reports. 18: 82-92. PMID 28052262 DOI: 10.1016/J.Celrep.2016.12.009  1
2017 Hodne K, Lipsett DB, Louch WE. Gene Transfer in Isolated Adult Cardiomyocytes. Methods in Molecular Biology (Clifton, N.J.). 1521: 169-182. PMID 27910048 DOI: 10.1007/978-1-4939-6588-5_11  1
2016 Wanichawan P, Hodne K, Hafver TL, Lunde M, Martinsen M, Louch WE, Sejersted OM, Carlson CR. Development of high affinity peptides that prevent phospholemman (PLM) inhibition of the sodium-calcium exchanger 1 (NCX1). The Biochemical Journal. PMID 27247424 DOI: 10.1042/BCJ20160465  1
2016 Frisk M, Ruud M, Espe EK, Aronsen JM, Røe ÅT, Zhang L, Norseng PA, Sejersted OM, Christensen G, Sjaastad I, Louch WE. Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis. Cardiovascular Research. PMID 27226008 DOI: 10.1093/cvr/cvw111  1
2016 Gattoni S, Røe ÅT, Frisk M, Louch WE, Niederer SA, Smith NP. The calcium-frequency response in the rat ventricular myocyte: an experimental and modelling study. The Journal of Physiology. PMID 26916026 DOI: 10.1113/JP272011  1
2016 Aronsen JM, Louch WE, Sjaastad I. Cardiomyocyte Ca2+ dynamics: clinical perspectives. Scandinavian Cardiovascular Journal : Scj. 50: 65-77. PMID 26729487 DOI: 10.3109/14017431.2015.1136079  1
2016 Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR. Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman. The Journal of Biological Chemistry. 291: 4561-79. PMID 26668322 DOI: 10.1074/jbc.M115.677898  1
2015 Aronsen JM, Skogestad J, Lewalle A, Louch WE, Hougen K, Stokke MK, Swift F, Niederer S, Smith NP, Sejersted OM, Sjaastad I. Hypokalaemia induces Ca(2+) overload and Ca(2+) waves in ventricular myocytes by reducing Na(+),K(+)-ATPase α2 activity. The Journal of Physiology. 593: 1509-21. PMID 25772299 DOI: 10.1113/jphysiol.2014.279893  1
2015 Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, et al. Deranged sodium to sudden death. The Journal of Physiology. 593: 1331-45. PMID 25772289 DOI: 10.1113/Jphysiol.2014.281204  1
2015 Louch WE, Koivumäki JT, Tavi P. Calcium signalling in developing cardiomyocytes: implications for model systems and disease. The Journal of Physiology. 593: 1047-63. PMID 25641733 DOI: 10.1113/jphysiol.2014.274712  1
2015 Ottesen AH, Louch WE, Carlson CR, Landsverk OJ, Kurola J, Johansen RF, Moe MK, Aronsen JM, Høiseth AD, Jarstadmarken H, Nygård S, Bjørås M, Sjaastad I, Pettilä V, Stridsberg M, et al. Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling. Journal of the American College of Cardiology. 65: 339-51. PMID 25634832 DOI: 10.1016/j.jacc.2014.10.065  1
2015 Herum KM, Lunde IG, Skrbic B, Louch WE, Hasic A, Boye S, Unger A, Brorson SH, Sjaastad I, Tønnessen T, Linke WA, Gomez MF, Christensen G. Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart. Cardiovascular Research. 106: 217-26. PMID 25587045 DOI: 10.1093/cvr/cvv002  1
2015 Palecek T, Fikrle M, Nemecek E, Bauerova L, Kuchynka P, Louch WE, Spicka I, Rysava R. Contemporary treatment of amyloid heart disease. Current Pharmaceutical Design. 21: 491-506. PMID 25483951  1
2015 Roe AT, Frisk M, Louch WE. Targeting cardiomyocyte Ca2+ homeostasis in heart failure. Current Pharmaceutical Design. 21: 431-48. PMID 25483944 DOI: 10.2174/138161282104141204124129  1
2015 Tinholt M, Stavik B, Louch W, Carlson CR, Sletten M, Ruf W, Skretting G, Sandset PM, Iversen N. Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells Plos One. 10. DOI: 10.1371/journal.pone.0117404  1
2014 Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaløy H, Louch WE, Tønnessen T, Sjaastad I, Sejersted OM, Carlson CR. Molecular basis of Calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure Journal of Biological Chemistry. 289: 33984-33998. PMID 25336645 DOI: 10.1074/jbc.M114.602581  1
2014 Land S, Niederer SA, Louch WE, Røe Ã…T, Aronsen JM, Stuckey DJ, Sikkel MB, Tranter MH, Lyon AR, Harding SE, Smith NP. Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1487-96. PMID 25239804 DOI: 10.1152/ajpheart.00443.2014  1
2014 Nordbø O, Lamata P, Land S, Niederer S, Aronsen JM, Louch WE, Sjaastad I, Martens H, Gjuvsland AB, Tøndel K, Torp H, Lohezic M, Schneider JE, Remme EW, Smith N, et al. A computational pipeline for quantification of mouse myocardial stiffness parameters. Computers in Biology and Medicine. 53: 65-75. PMID 25129018 DOI: 10.1016/j.compbiomed.2014.07.013  1
2014 Frisk M, Koivumäki JT, Norseng PA, Maleckar MM, Sejersted OM, Louch WE. Variable t-tubule organization and Ca2+ homeostasis across the atria. American Journal of Physiology. Heart and Circulatory Physiology. 307: H609-20. PMID 24951751 DOI: 10.1152/ajpheart.00295.2014  1
2014 Misceo D, Holmgren A, Louch WE, Holme PA, Mizobuchi M, Morales RJ, De Paula AM, Stray-Pedersen A, Lyle R, Dalhus B, Christensen G, Stormorken H, Tjønnfjord GE, Frengen E. A dominant STIM1 mutation causes Stormorken syndrome. Human Mutation. 35: 556-64. PMID 24619930 DOI: 10.1002/humu.22544  1
2013 Land S, Niederer SA, Louch WE, Sejersted OM, Smith NP. Integrating multi-scale data to create a virtual physiological mouse heart. Interface Focus. 3: 20120076. PMID 24427525 DOI: 10.1098/rsfs.2012.0076  1
2013 Øyehaug L, Loose KØ, Jølle GF, Røe ÅT, Sjaastad I, Christensen G, Sejersted OM, Louch WE. Synchrony of cardiomyocyte Ca(2+) release is controlled by T-tubule organization, SR Ca(2+) content, and ryanodine receptor Ca(2+) sensitivity. Biophysical Journal. 104: 1685-97. PMID 23601316 DOI: 10.1016/j.bpj.2013.03.022  1
2013 Land S, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sjaastad I, Sejersted OM, Smith NP. Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice. Biophysical Journal. 104: 1349-56. PMID 23528094 DOI: 10.1016/j.bpj.2013.01.042  1
2013 Louch WE, Lyon AR. Mind the store: modulating Ca(2+) reuptake with a leaky sarcoplasmic reticulum. Cardiovascular Research. 98: 165-8. PMID 23524302 DOI: 10.1093/cvr/cvt069  1
2013 Stokke MK, Tovsrud N, Louch WE, Øyehaug L, Hougen K, Sejersted OM, Swift F, Sjaastad I. I(CaL) inhibition prevents arrhythmogenic Ca(2+) waves caused by abnormal Ca(2+) sensitivity of RyR or SR Ca(2+) accumulation. Cardiovascular Research. 98: 315-25. PMID 23417043 DOI: 10.1093/cvr/cvt037  1
2013 Louch WE, Hake J, Mørk HK, Hougen K, Skrbic B, Ursu D, Tønnessen T, Sjaastad I, Sejersted OM. Slow Ca²⁺ sparks de-synchronize Ca²⁺ release in failing cardiomyocytes: evidence for altered configuration of Ca²⁺ release units? Journal of Molecular and Cellular Cardiology. 58: 41-52. PMID 23376034 DOI: 10.1016/j.yjmcc.2013.01.014  1
2012 Louch WE, Stokke MK, Sjaastad I, Christensen G, Sejersted OM. No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium. Physiology (Bethesda, Md.). 27: 308-23. PMID 23026754 DOI: 10.1152/physiol.00021.2012  1
2012 Li L, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sejersted OM, Smith NP. Sodium accumulation in SERCA knockout-induced heart failure. Biophysical Journal. 102: 2039-48. PMID 22824267 DOI: 10.1016/j.bpj.2012.03.045  1
2012 Røsjø H, Stridsberg M, Florholmen G, Stensløkken KO, Ottesen AH, Sjaastad I, Husberg C, Dahl MB, Øie E, Louch WE, Omland T, Christensen G. Secretogranin II; a protein increased in the myocardium and circulation in heart failure with cardioprotective properties. Plos One. 7: e37401. PMID 22655045 DOI: 10.1371/journal.pone.0037401  1
2012 Land S, Niederer SA, Aronsen JM, Espe EK, Zhang L, Louch WE, Sjaastad I, Sejersted OM, Smith NP. An analysis of deformation-dependent electromechanical coupling in the mouse heart. The Journal of Physiology. 590: 4553-69. PMID 22615436 DOI: 10.1113/jphysiol.2012.231928  1
2012 Louch WE, Vangheluwe P, Bito V, Raeymaekers L, Wuytack F, Sipido KR. Phospholamban ablation in hearts expressing the high affinity SERCA2b isoform normalizes global Ca²⁺ homeostasis but not Ca²⁺-dependent hypertrophic signaling. American Journal of Physiology. Heart and Circulatory Physiology. 302: H2574-82. PMID 22505640 DOI: 10.1152/ajpheart.01166.2011  1
2012 Swift F, Franzini-Armstrong C, Øyehaug L, Enger UH, Andersson KB, Christensen G, Sejersted OM, Louch WE. Extreme sarcoplasmic reticulum volume loss and compensatory T-tubule remodeling after Serca2 knockout. Proceedings of the National Academy of Sciences of the United States of America. 109: 3997-4001. PMID 22355118 DOI: 10.1073/pnas.1120172109  1
2012 Eidet JR, Utheim OA, Raeder S, Dartt DA, Lyberg T, Carreras E, Huynh TT, Messelt EB, Louch WE, Roald B, Utheim TP. Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium. Experimental Eye Research. 94: 109-16. PMID 22154551 DOI: 10.1016/j.exer.2011.11.015  1
2012 Bjørnstad JL, Skrbic B, Marstein HS, Hasic A, Sjaastad I, Louch WE, Florholmen G, Christensen G, Tønnessen T. Inhibition of SMAD2 phosphorylation preserves cardiac function during pressure overload. Cardiovascular Research. 93: 100-10. PMID 22049534 DOI: 10.1093/cvr/cvr294  1
2011 Finsen AV, Lunde IG, Sjaastad I, Østli EK, Lyngra M, Jarstadmarken HO, Hasic A, Nygård S, Wilcox-Adelman SA, Goetinck PF, Lyberg T, Skrbic B, Florholmen G, Tønnessen T, Louch WE, et al. Syndecan-4 is essential for development of concentric myocardial hypertrophy via stretch-induced activation of the calcineurin-NFAT pathway. Plos One. 6: e28302. PMID 22164265 DOI: 10.1371/journal.pone.0028302  1
2011 Louch WE, Sheehan KA, Wolska BM. Methods in cardiomyocyte isolation, culture, and gene transfer. Journal of Molecular and Cellular Cardiology. 51: 288-98. PMID 21723873 DOI: 10.1016/j.yjmcc.2011.06.012  0.01
2011 Waehre A, Halvorsen B, Yndestad A, Husberg C, Sjaastad I, NygÃ¥rd S, Dahl CP, Ahmed MS, Finsen AV, Reims H, Louch WE, Hilfiker-Kleiner D, Vinge LE, Roald B, Attramadal H, et al. Lack of chemokine signaling through CXCR5 causes increased mortality, ventricular dilatation and deranged matrix during cardiac pressure overload. Plos One. 6: e18668. PMID 21533157 DOI: 10.1371/journal.pone.0018668  1
2011 Wanichawan P, Louch WE, Hortemo KH, AustbØ B, Lunde PK, Scott JD, Sejersted OM, Carlson CR. Full-length cardiac Na+/Ca2+ exchanger 1 protein is not phosphorylated by protein kinase A American Journal of Physiology - Cell Physiology. 300. PMID 21289289 DOI: 10.1152/ajpcell.00196.2010  1
2011 Li L, Louch WE, Niederer SA, Andersson KB, Christensen G, Sejersted OM, Smith NP. Calcium dynamics in the ventricular myocytes of SERCA2 knockout mice: A modeling study. Biophysical Journal. 100: 322-31. PMID 21244828 DOI: 10.1016/j.bpj.2010.11.048  1
2011 Stokke MK, Briston SJ, Jølle GF, Manzoor I, Louch WE, Øyehaug L, Christensen G, Eisner DA, Trafford AW, Sejersted OM, Sjaastad I. Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content. Cardiovascular Research. 90: 503-12. PMID 21242164 DOI: 10.1093/Cvr/Cvr013  1
2011 Liu XH, Zhang ZY, Andersson KB, Husberg C, Enger UH, Ræder MG, Christensen G, Louch WE. Cardiomyocyte-specific disruption of Serca2 in adult mice causes sarco(endo)plasmic reticulum stress and apoptosis. Cell Calcium. 49: 201-7. PMID 20965565 DOI: 10.1016/j.ceca.2010.09.009  1
2010 Kuchynka P, Palecek T, Hrbackova H, Vitkova I, Simek S, Nemecek E, Aster V, Louch WE, Aschermann M, Linhart A. Herpes simplex virus-induced cardiomyopathy successfully treated with acyclovir. Wiener Klinische Wochenschrift. 122: 592-5. PMID 20865454 DOI: 10.1007/s00508-010-1456-4  1
2010 Louch WE, Hake J, Jølle GF, Mørk HK, Sjaastad I, Lines GT, Sejersted OM. Control of Ca2+ release by action potential configuration in normal and failing murine cardiomyocytes. Biophysical Journal. 99: 1377-86. PMID 20816049 DOI: 10.1016/j.bpj.2010.06.055  1
2010 Louch WE, Sejersted OM, Swift F. There goes the neighborhood: pathological alterations in T-tubule morphology and consequences for cardiomyocyte Ca2+ handling. Journal of Biomedicine & Biotechnology. 2010: 503906. PMID 20396394 DOI: 10.1155/2010/503906  1
2010 Palecek T, Kuchynka P, Hulinska D, Schramlova J, Hrbackova H, Vitkova I, Simek S, Horak J, Louch WE, Linhart A. Presence of Borrelia burgdorferi in endomyocardial biopsies in patients with new-onset unexplained dilated cardiomyopathy. Medical Microbiology and Immunology. 199: 139-43. PMID 20052487 DOI: 10.1007/s00430-009-0141-6  1
2010 Stokke MK, Hougen K, Sjaastad I, Louch WE, Briston SJ, Enger UH, Andersson KB, Christensen G, Eisner DA, Sejersted OM, Trafford AW. Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes. Cardiovascular Research. 86: 63-71. PMID 20019150 DOI: 10.1093/Cvr/Cvp401  1
2010 Louch WE, Hougen K, Mørk HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM. Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout. The Journal of Physiology. 588: 465-78. PMID 20008467 DOI: 10.1113/jphysiol.2009.183517  1
2010 Kuchynka P, Palecek T, Vilikus Z, Havranek S, Taborska K, Louch WE, Linhart A. Cardiac structural and functional changes in competitive amateur cyclists. Echocardiography (Mount Kisco, N.Y.). 27: 11-6. PMID 19765071 DOI: 10.1111/j.1540-8175.2009.00965.x  1
2009 Andersson KB, Finsen AV, Sjåland C, Winer LH, Sjaastad I, Odegaard A, Louch WE, Wang Y, Chen J, Chien KR, Sejersted OM, Christensen G. Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models. Cell Calcium. 46: 219-25. PMID 19692123 DOI: 10.1016/J.Ceca.2009.07.004  1
2009 Andersson KB, Birkeland JA, Finsen AV, Louch WE, Sjaastad I, Wang Y, Chen J, Molkentin JD, Chien KR, Sejersted OM, Christensen G. Moderate heart dysfunction in mice with inducible cardiomyocyte-specific excision of the Serca2 gene. Journal of Molecular and Cellular Cardiology. 47: 180-7. PMID 19328205 DOI: 10.1016/J.Yjmcc.2009.03.013  1
2009 Mørk HK, Sjaastad I, Sejersted OM, Louch WE. Slowing of cardiomyocyte Ca2+ release and contraction during heart failure progression in postinfarction mice. American Journal of Physiology. Heart and Circulatory Physiology. 296: H1069-79. PMID 19201998 DOI: 10.1152/ajpheart.01009.2008  1
2008 Bøkenes J, Aronsen JM, Birkeland JA, Henriksen UL, Louch WE, Sjaastad I, Sejersted OM. Slow contractions characterize failing rat hearts. Basic Research in Cardiology. 103: 328-44. PMID 18347833 DOI: 10.1007/s00395-008-0719-y  1
2008 Swift F, Birkeland JA, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM. Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure. Cardiovascular Research. 78: 71-8. PMID 18203708 DOI: 10.1093/cvr/cvn013  1
2007 Mørk HK, Sjaastad I, Sande JB, Periasamy M, Sejersted OM, Louch WE. Increased cardiomyocyte function and Ca2+ transients in mice during early congestive heart failure. Journal of Molecular and Cellular Cardiology. 43: 177-86. PMID 17574269 DOI: 10.1016/j.yjmcc.2007.05.004  1
2006 Vangheluwe P, Tjwa M, Van Den Bergh A, Louch WE, Beullens M, Dode L, Carmeliet P, Kranias E, Herijgers P, Sipido KR, Raeymaekers L, Wuytack F. A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span. Journal of Molecular and Cellular Cardiology. 41: 308-17. PMID 16814319 DOI: 10.1016/J.Yjmcc.2006.05.014  1
2006 Louch WE, Mørk HK, Sexton J, Strømme TA, Laake P, Sjaastad I, Sejersted OM. T-tubule disorganization and reduced synchrony of Ca2+ release in murine cardiomyocytes following myocardial infarction. The Journal of Physiology. 574: 519-33. PMID 16709642 DOI: 10.1113/jphysiol.2006.107227  1
2006 Lines GT, Sande JB, Louch WE, Mørk HK, Grøttum P, Sejersted OM. Contribution of the Na+/Ca2+ exchanger to rapid Ca2+ release in cardiomyocytes. Biophysical Journal. 91: 779-92. PMID 16679359 DOI: 10.1529/biophysj.105.072447  1
2005 Louch WE, Ferrier GR, Howlett SE. Attentuation of cardiac stunning by losartan in a cellular model of ischemia and reperfusion is accompanied by increased sarcoplasmic reticulum Ca2+ stores and prevention of cytosolic Ca2+ elevation. The Journal of Pharmacology and Experimental Therapeutics. 312: 238-47. PMID 15316090 DOI: 10.1124/Jpet.104.072769  1
2004 Louch WE, Bito V, Heinzel FR, Macianskiene R, Vanhaecke J, Flameng W, Mubagwa K, Sipido KR. Reduced synchrony of Ca2+ release with loss of T-tubules-a comparison to Ca2+ release in human failing cardiomyocytes. Cardiovascular Research. 62: 63-73. PMID 15023553 DOI: 10.1016/j.cardiores.2003.12.031  1
2003 Vangheluwe P, Louch WE, Ver Heyen M, Sipido K, Raeymaekers L, Wuytack F. Ca2+ transport ATPase isoforms SERCA2a and SERCA2b are targeted to the same sites in the murine heart. Cell Calcium. 34: 457-64. PMID 14572804  1
2003 Au A, Louch WE, Ferrier GR, Howlett SE. L-Arginine ameliorates effects of ischemia and reperfusion in isolated cardiac myocytes. European Journal of Pharmacology. 476: 45-54. PMID 12969748 DOI: 10.1016/S0014-2999(03)02175-7  1
2002 Louch WE, Ferrier GR, Howlett SE. Changes in excitation-contraction coupling in an isolated ventricular myocyte model of cardiac stunning. American Journal of Physiology. Heart and Circulatory Physiology. 283: H800-10. PMID 12124230 DOI: 10.1152/Ajpheart.00020.2002  1
2000 Louch WE, Ferrier GR, Howlett SE. Losartan improves recovery of contraction and inhibits transient inward current in a cellular model of cardiac ischemia and reperfusion. The Journal of Pharmacology and Experimental Therapeutics. 295: 697-704. PMID 11046108  1
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