Ranjit S. Bindra, Ph.D. - Publications

2005 Yale University, New Haven, CT 
Molecular Biology

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Neel BG, Xu Y, Taylor P, Andrade J, Ueberheide B, Shuch B, Glazer PM, Bindra RS, Moran MF, Linehan WM. Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. Cancer Research. PMID 30297534 DOI: 10.1158/0008-5472.CAN-18-0901  0.84
2018 Sulkowski PL, Sundaram RK, Oeck S, Corso CD, Liu Y, Noorbakhsh S, Niger M, Boeke M, Ueno D, Kalathil AN, Bao X, Li J, Shuch B, Bindra RS, Glazer PM. Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair. Nature Genetics. PMID 30013182 DOI: 10.1038/s41588-018-0170-4  0.84
2017 Sulkowski PL, Corso CD, Robinson ND, Scanlon SE, Purshouse KR, Bai H, Liu Y, Sundaram RK, Hegan DC, Fons NR, Breuer GA, Song Y, Mishra-Gorur K, De Feyter HM, de Graaf RA, ... ... Bindra RS, et al. 2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity. Science Translational Medicine. 9. PMID 28148839 DOI: 10.1126/scitranslmed.aal2463  0.84
2015 Goglia AG, Delsite R, Luz AN, Shahbazian D, Salem AF, Sundaram RK, Chiaravalli J, Hendrikx PJ, Wilshire JA, Jasin M, Kluger HM, Glickman JF, Powell SN, Bindra RS. Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors. Molecular Cancer Therapeutics. 14: 326-42. PMID 25512618 DOI: 10.1158/1535-7163.MCT-14-0765  0.32
2014 Wang C, Roberts KB, Bindra RS, Chiang VL, Yu JB. Delayed cerebral vasculopathy following cranial radiation therapy for pediatric tumors. Pediatric Neurology. 50: 549-56. PMID 24739378 DOI: 10.1016/j.pediatrneurol.2013.09.018  0.84
2013 Shahbazian D, Bindra RS, Kluger HM, Glazer PM. Radiation sensitivity and sensitization in melanoma. Pigment Cell & Melanoma Research. 26: 928-30. PMID 23870422 DOI: 10.1111/pcmr.12147  0.84
2013 Bindra RS, Goglia AG, Jasin M, Powell SN. Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells. Nucleic Acids Research. 41: e115. PMID 23585275 DOI: 10.1093/nar/gkt255  0.84
2010 Hegan DC, Lu Y, Stachelek GC, Crosby ME, Bindra RS, Glazer PM. Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130. Proceedings of the National Academy of Sciences of the United States of America. 107: 2201-6. PMID 20133863 DOI: 10.1073/pnas.0904783107  0.84
2009 Glazer PM, Bindra RS. Introduction: the evolving picture of the hypoxic tumour microenvironment. Current Molecular Medicine. 9: 399-400. PMID 19519396  0.84
2009 Powell SN, Bindra RS. Targeting the DNA damage response for cancer therapy. Dna Repair. 8: 1153-65. PMID 19501553 DOI: 10.1016/j.dnarep.2009.04.011  0.84
2007 Bindra RS, Crosby ME, Glazer PM. Regulation of DNA repair in hypoxic cancer cells Cancer and Metastasis Reviews. 26: 249-260. PMID 17415527 DOI: 10.1007/s10555-007-9061-3  0.84
2007 Bindra RS, Glazer PM. Co-repression of mismatch repair gene expression by hypoxia in cancer cells: role of the Myc/Max network. Cancer Letters. 252: 93-103. PMID 17275176 DOI: 10.1016/j.canlet.2006.12.011  0.84
2007 Huang LE, Bindra RS, Glazer PM, Harris AL. Hypoxia-induced genetic instability--a calculated mechanism underlying tumor progression. Journal of Molecular Medicine (Berlin, Germany). 85: 139-48. PMID 17180667 DOI: 10.1007/s00109-006-0133-6  0.84
2007 Bindra RS, Glazer PM. Repression of RAD51 gene expression by E2F4/p130 complexes in hypoxia. Oncogene. 26: 2048-57. PMID 17001309 DOI: 10.1038/sj.onc.1210001  0.84
2006 Bindra RS, Glazer PM. Basal repression of BRCA1 by multiple E2Fs and pocket proteins at adjacent E2F sites. Cancer Biology & Therapy. 5: 1400-7. PMID 17106239  0.84
2006 Gibson SL, Bindra RS, Glazer PM. CHK2-dependent phosphorylation of BRCA1 in hypoxia. Radiation Research. 166: 646-51. PMID 17007555 DOI: 10.1667/RR0660.1  0.84
2005 Bindra RS, Schaffer PJ, Meng A, Woo J, Måseide K, Roth ME, Lizardi P, Hedley DW, Bristow RG, Glazer PM. Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability. Annals of the New York Academy of Sciences. 1059: 184-95. PMID 16382054 DOI: 10.1196/annals.1339.049  0.84
2005 Bindra RS, Gibson SL, Meng A, Westermark U, Jasin M, Pierce AJ, Bristow RG, Classon MK, Glazer PM. Hypoxia-induced down-regulation of BRCA1 expression by E2Fs. Cancer Research. 65: 11597-604. PMID 16357170 DOI: 10.1158/0008-5472.CAN-05-2119  0.84
2005 Gibson SL, Bindra RS, Glazer PM. Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner. Cancer Research. 65: 10734-41. PMID 16322218 DOI: 10.1158/0008-5472.CAN-05-1160  0.84
2005 Meng AX, Jalali F, Cuddihy A, Chan N, Bindra RS, Glazer PM, Bristow RG. Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 76: 168-76. PMID 16026872 DOI: 10.1016/j.radonc.2005.06.025  0.84
2005 Bindra RS, Glazer PM. Genetic instability and the tumor microenvironment: towards the concept of microenvironment-induced mutagenesis. Mutation Research. 569: 75-85. PMID 15603753 DOI: 10.1016/j.mrfmmm.2004.03.013  0.84
2004 Bindra RS, Schaffer PJ, Meng A, Woo J, Måseide K, Roth ME, Lizardi P, Hedley DW, Bristow RG, Glazer PM. Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells. Molecular and Cellular Biology. 24: 8504-18. PMID 15367671 DOI: 10.1128/MCB.24.19.8504-8518.2004  0.84
2003 Mihaylova VT, Bindra RS, Yuan J, Campisi D, Narayanan L, Jensen R, Giordano F, Johnson RS, Rockwell S, Glazer PM. Decreased expression of the DNA mismatch repair gene Mlh1 under hypoxic stress in mammalian cells. Molecular and Cellular Biology. 23: 3265-73. PMID 12697826 DOI: 10.1128/MCB.23.9.3265-3273.2003  0.84
2002 Bindra RS, Vasselli JR, Stearman R, Linehan WM, Klausner RD. VHL-mediated hypoxia regulation of cyclin D1 in renal carcinoma cells. Cancer Research. 62: 3014-9. PMID 12036906  0.84
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