Karen E. Knudsen - Publications

University of Cincinnati, Cincinnati, OH 
Cell Biology, Oncology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 McNair C, Urbanucci A, Comstock CE, Augello MA, Goodwin JF, Launchbury R, Zhao SG, Schiewer MJ, Ertel A, Karnes J, Davicioni E, Wang L, Wang Q, Mills IG, Feng FY, ... ... Knudsen KE, et al. Cell cycle-coupled expansion of AR activity promotes cancer progression. Oncogene. PMID 27669432 DOI: 10.1038/Onc.2016.334  0.68
2016 Kim H, Alshalalfa M, Hoffman-Censits J, Lallas CD, Davicioni E, Lin J, Birbe R, Erho N, Lehrer J, Ashab HAD, Takhar M, Olson A, Lam LLC, Kelly WK, Knudsen KE, et al. Potential Impact on Clinical Decision Making via a Genome-Wide Expression Profiling: A Case Report Urology Case Reports. 9: 51-54. DOI: 10.1016/j.eucr.2016.08.010  0.68
2015 Schrecengost RS, Keller SN, Schiewer MJ, Knudsen KE, Smith CD. Downregulation of Critical Oncogenes by the Selective SK2 Inhibitor ABC294640 Hinders Prostate Cancer Progression. Molecular Cancer Research : McR. PMID 26271487 DOI: 10.1158/1541-7786.Mcr-14-0626  0.68
2015 Feng FY, de Bono JS, Rubin MA, Knudsen KE. Chromatin to Clinic: The Molecular Rationale for PARP1 Inhibitor Function. Molecular Cell. 58: 925-34. PMID 26091341 DOI: 10.1016/J.Molcel.2015.04.016  0.68
2015 Hovelson DH, McDaniel AS, Cani AK, Johnson B, Rhodes K, Williams PD, Bandla S, Bien G, Choppa P, Hyland F, Gottimukkala R, Liu G, Manivannan M, Schageman J, Ballesteros-Villagrana E, ... ... Knudsen KE, et al. Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors. Neoplasia (New York, N.Y.). 17: 385-99. PMID 25925381 DOI: 10.1016/J.Neo.2015.03.004  0.68
2015 Augello MA, Berman-Booty LD, Carr R, Yoshida A, Dean JL, Schiewer MJ, Feng FY, Tomlins SA, Gao E, Koch WJ, Benovic JL, Diehl JA, Knudsen KE. Consequence of the tumor-associated conversion to cyclin D1b. Embo Molecular Medicine. 7: 628-47. PMID 25787974 DOI: 10.15252/Emmm.201404242  0.68
2014 Prensner JR, Chen W, Han S, Iyer MK, Cao Q, Kothari V, Evans JR, Knudsen KE, Paulsen MT, Ljungman M, Lawrence TS, Chinnaiyan AM, Feng FY. The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc. Neoplasia (New York, N.Y.). 16: 900-8. PMID 25425964 DOI: 10.1016/J.Neo.2014.09.001  0.68
2014 Jimbo M, Knudsen KE, Brody JR. Fusing transcriptomics to progressive prostate cancer. The American Journal of Pathology. 184: 2608-10. PMID 25128905 DOI: 10.1016/J.Ajpath.2014.08.001  0.68
2014 Den RB, Feng FY, Showalter TN, Mishra MV, Trabulsi EJ, Lallas CD, Gomella LG, Kelly WK, Birbe RC, McCue PA, Ghadessi M, Yousefi K, Davicioni E, Knudsen KE, Dicker AP. Genomic prostate cancer classifier predicts biochemical failure and metastases in patients after postoperative radiation therapy. International Journal of Radiation Oncology, Biology, Physics. 89: 1038-46. PMID 25035207 DOI: 10.1016/J.Ijrobp.2014.04.052  0.68
2014 Dressing GE, Knutson TP, Schiewer MJ, Daniel AR, Hagan CR, Diep CH, Knudsen KE, Lange CA. Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 28: 442-57. PMID 24606123 DOI: 10.1210/Me.2013-1196  0.68
2014 Prensner JR, Chen W, Iyer MK, Cao Q, Ma T, Han S, Sahu A, Malik R, Wilder-Romans K, Navone N, Logothetis CJ, Araujo JC, Pisters LL, Tewari AK, Canman CE, ... Knudsen KE, et al. PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer. Cancer Research. 74: 1651-60. PMID 24473064 DOI: 10.1158/0008-5472.Can-13-3159  0.68
2014 Schrecengost RS, Dean JL, Goodwin JF, Schiewer MJ, Urban MW, Stanek TJ, Sussman RT, Hicks JL, Birbe RC, Draganova-Tacheva RA, Visakorpi T, DeMarzo AM, McMahon SB, Knudsen KE. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression. Cancer Research. 74: 272-86. PMID 24197134 DOI: 10.1158/0008-5472.Can-13-1954  0.68
2014 Steffen JD, Tholey RM, Langelier MF, Planck JL, Schiewer MJ, Lal S, Bildzukewicz NA, Yeo CJ, Knudsen KE, Brody JR, Pascal JM. Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer. Cancer Research. 74: 31-7. PMID 24189460 DOI: 10.1158/0008-5472.Can-13-1701  0.68
2014 Goodwin JF, Knudsen KE. Beyond DNA repair: DNA-PK function in cancer Cancer Discovery. 4: 1126-1139. DOI: 10.1158/2159-8290.CD-14-0358  0.68
2014 Schrecengost RS, Augello MA, Knudsen KE. Androgen receptor regulation of prostate cancer progression and metastasis Signaling Pathways and Molecular Mediators in Metastasis. 277-309. DOI: 10.1007/978-94-007-2558-4_12  0.68
2013 Goodwin JF, Schiewer MJ, Dean JL, Schrecengost RS, de Leeuw R, Han S, Ma T, Den RB, Dicker AP, Feng FY, Knudsen KE. A hormone-DNA repair circuit governs the response to genotoxic insult. Cancer Discovery. 3: 1254-71. PMID 24027197 DOI: 10.1158/2159-8290.Cd-13-0108  0.68
2013 Sussman RT, Stanek TJ, Esteso P, Gearhart JD, Knudsen KE, McMahon SB. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2). The Journal of Biological Chemistry. 288: 24234-46. PMID 23760504 DOI: 10.1074/Jbc.M113.469783  0.68
2013 Comstock CE, Augello MA, Goodwin JF, de Leeuw R, Schiewer MJ, Ostrander WF, Burkhart RA, McClendon AK, McCue PA, Trabulsi EJ, Lallas CD, Gomella LG, Centenera MM, Brody JR, Butler LM, ... ... Knudsen KE, et al. Targeting cell cycle and hormone receptor pathways in cancer. Oncogene. 32: 5481-91. PMID 23708653 DOI: 10.1038/Onc.2013.83  0.68
2013 Balasubramaniam S, Comstock CE, Ertel A, Jeong KW, Stallcup MR, Addya S, McCue PA, Ostrander WF, Augello MA, Knudsen KE. Aberrant BAF57 signaling facilitates prometastatic phenotypes. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 2657-67. PMID 23493350 DOI: 10.1158/1078-0432.Ccr-12-3049  0.68
2013 Augello MA, Burd CJ, Birbe R, McNair C, Ertel A, Magee MS, Frigo DE, Wilder-Romans K, Shilkrut M, Han S, Jernigan DL, Dean JL, Fatatis A, McDonnell DP, Visakorpi T, ... ... Knudsen KE, et al. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes. The Journal of Clinical Investigation. 123: 493-508. PMID 23257359 DOI: 10.1172/Jci64750  0.68
2012 Schiewer MJ, Goodwin JF, Han S, Brenner JC, Augello MA, Dean JL, Liu F, Planck JL, Ravindranathan P, Chinnaiyan AM, McCue P, Gomella LG, Raj GV, Dicker AP, Brody JR, ... ... Knudsen KE, et al. Dual roles of PARP-1 promote cancer growth and progression. Cancer Discovery. 2: 1134-49. PMID 22993403 DOI: 10.1158/2159-8290.Cd-12-0120  0.68
2012 Centenera MM, Gillis JL, Hanson AR, Jindal S, Taylor RA, Risbridger GP, Sutherland PD, Scher HI, Raj GV, Knudsen KE, Yeadon T, Tilley WD, Butler LM. Evidence for efficacy of new Hsp90 inhibitors revealed by ex vivo culture of human prostate tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3562-70. PMID 22573351 DOI: 10.1158/1078-0432.Ccr-12-0782  0.68
2011 Augello MA, Hickey TE, Knudsen KE. FOXA1: Master of steroid receptor function in cancer Embo Journal. 30: 3885-3894. PMID 21934649 DOI: 10.1038/Emboj.2011.340  0.68
2011 Bryant KG, Camacho J, Jasmin JF, Wang C, Addya S, Casimiro MC, Fortina P, Balasubramaniam S, Knudsen KE, Schwarting R, Lisanti MP, Mercier I. Caveolin-1 overexpression enhances androgen-dependent growth and proliferation in the mouse prostate. The International Journal of Biochemistry & Cell Biology. 43: 1318-29. PMID 21601007 DOI: 10.1016/J.Biocel.2011.04.019  0.68
2011 Comstock CE, Augello MA, Schiewer MJ, Karch J, Burd CJ, Ertel A, Knudsen ES, Jessen WJ, Aronow BJ, Knudsen KE. Cyclin D1 is a selective modifier of androgen-dependent signaling and androgen receptor function. The Journal of Biological Chemistry. 286: 8117-27. PMID 21212260 DOI: 10.1074/Jbc.M110.170720  0.48
2010 Sharma A, Yeow WS, Ertel A, Coleman I, Clegg N, Thangavel C, Morrissey C, Zhang X, Comstock CE, Witkiewicz AK, Gomella L, Knudsen ES, Nelson PS, Knudsen KE. The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. The Journal of Clinical Investigation. 120: 4478-92. PMID 21099110 DOI: 10.1172/Jci44239  0.68
2010 Olshavsky NA, Comstock CE, Schiewer MJ, Augello MA, Hyslop T, Sette C, Zhang J, Parysek LM, Knudsen KE. Identification of ASF/SF2 as a critical, allele-specific effector of the cyclin D1b oncogene. Cancer Research. 70: 3975-84. PMID 20460515 DOI: 10.1158/0008-5472.Can-09-3468  0.68
2010 Knudsen KE, Penning TM. Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancer. Trends in Endocrinology and Metabolism: Tem. 21: 315-24. PMID 20138542 DOI: 10.1016/J.Tem.2010.01.002  0.68
2010 Paronetto MP, Cappellari M, Busà R, Pedrotti S, Vitali R, Comstock C, Hyslop T, Knudsen KE, Sette C. Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68. Cancer Research. 70: 229-39. PMID 20028857 DOI: 10.1158/0008-5472.Can-09-2788  0.68
2009 Miao J, Fang S, Lee J, Comstock C, Knudsen KE, Kemper JK. Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis. Molecular and Cellular Biology. 29: 6170-81. PMID 19805516 DOI: 10.1128/Mcb.00825-09  0.68
2009 Comstock CE, Augello MA, Benito RP, Karch J, Tran TH, Utama FE, Tindall EA, Wang Y, Burd CJ, Groh EM, Hoang HN, Giles GG, Severi G, Hayes VM, Henderson BE, ... ... Knudsen KE, et al. Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 5338-49. PMID 19706803 DOI: 10.1158/1078-0432.Ccr-08-2865  0.68
2009 Knudsen KE, Scher HI. Starving the addiction: New opportunities for durable suppression of AR signaling in prostate cancer Clinical Cancer Research. 15: 4792-4798. PMID 19638458 DOI: 10.1158/1078-0432.Ccr-08-2660  0.68
2009 Millar EK, Dean JL, McNeil CM, O'Toole SA, Henshall SM, Tran T, Lin J, Quong A, Comstock CE, Witkiewicz A, Musgrove EA, Rui H, Lemarchand L, Setiawan VW, Haiman CA, ... Knudsen KE, et al. Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome. Oncogene. 28: 1812-20. PMID 19287456 DOI: 10.1038/Onc.2009.13  0.68
2009 Schiewer MJ, Morey LM, Burd CJ, Liu Y, Merry DE, Ho SM, Knudsen KE. Cyclin D1 repressor domain mediates proliferation and survival in prostate cancer Oncogene. 28: 1016-1027. PMID 19079343 DOI: 10.1038/Onc.2008.446  0.68
2008 Wang Y, Dean JL, Millar EK, Tran TH, McNeil CM, Burd CJ, Henshall SM, Utama FE, Witkiewicz A, Rui H, Sutherland RL, Knudsen KE, Knudsen ES. Cyclin D1b is aberrantly regulated in response to therapeutic challenge and promotes resistance to estrogen antagonists. Cancer Research. 68: 5628-38. PMID 18632615 DOI: 10.1158/0008-5472.Can-07-3170  0.68
2008 Link KA, Balasubramaniam S, Sharma A, Comstock CE, Godoy-Tundidor S, Powers N, Cao KH, Haelens A, Claessens F, Revelo MP, Knudsen KE. Targeting the BAF57 SWI/SNF subunit in prostate cancer: a novel platform to control androgen receptor activity. Cancer Research. 68: 4551-8. PMID 18559499 DOI: 10.1158/0008-5472.Can-07-6392  0.68
2008 Olshavsky NA, Groh EM, Comstock CE, Morey LM, Wang Y, Revelo MP, Burd C, Meller J, Knudsen KE. Cyclin D3 action in androgen receptor regulation and prostate cancer. Oncogene. 27: 3111-21. PMID 18084330 DOI: 10.1038/Sj.Onc.1210981  0.68
2007 Hess-Wilson JK, Webb SL, Daly HK, Leung YK, Boldison J, Comstock CE, Sartor MA, Ho SM, Knudsen KE. Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status. Environmental Health Perspectives. 115: 1646-53. PMID 18007998 DOI: 10.1289/Ehp.10283  0.68
2007 vom Saal FS, Akingbemi BT, Belcher SM, Birnbaum LS, Crain DA, Eriksen M, Farabollini F, Guillette LJ, Hauser R, Heindel JJ, Ho SM, Hunt PA, Iguchi T, Jobling S, Kanno J, ... ... Knudsen KE, et al. Chapel Hill bisphenol A expert panel consensus statement: integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure. Reproductive Toxicology (Elmsford, N.Y.). 24: 131-8. PMID 17768031 DOI: 10.1016/J.Reprotox.2007.07.005  0.68
2007 Sharma A, Comstock CE, Knudsen ES, Cao KH, Hess-Wilson JK, Morey LM, Barrera J, Knudsen KE. Retinoblastoma tumor suppressor status is a critical determinant of therapeutic response in prostate cancer cells. Cancer Research. 67: 6192-203. PMID 17616676 DOI: 10.1158/0008-5472.Can-06-4424  0.68
2007 Comstock CE, Revelo MP, Buncher CR, Knudsen KE. Impact of differential cyclin D1 expression and localisation in prostate cancer. British Journal of Cancer. 96: 970-9. PMID 17375037 DOI: 10.1038/Sj.Bjc.6603615  0.68
2006 Wetherill YB, Hess-Wilson JK, Comstock CE, Shah SA, Buncher CR, Sallans L, Limbach PA, Schwemberger S, Babcock GF, Knudsen KE. Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer. Molecular Cancer Therapeutics. 5: 3181-90. PMID 17172422 DOI: 10.1158/1535-7163.Mct-06-0272  0.68
2006 Burd CJ, Morey LM, Knudsen KE. Androgen receptor corepressors and prostate cancer. Endocrine-Related Cancer. 13: 979-94. PMID 17158750 DOI: 10.1677/Erc.1.01115  0.48
2006 Knudsen KE, Diehl JA, Haiman CA, Knudsen ES. Cyclin D1: polymorphism, aberrant splicing and cancer risk. Oncogene. 25: 1620-8. PMID 16550162 DOI: 10.1038/Sj.Onc.1209371  0.68
2006 Burd CJ, Petre CE, Morey LM, Wang Y, Revelo MP, Haiman CA, Lu S, Fenoglio-Preiser CM, Li J, Knudsen ES, Wong J, Knudsen KE. Cyclin D1b variant influences prostate cancer growth through aberrant androgen receptor regulation Proceedings of the National Academy of Sciences of the United States of America. 103: 2190-2195. PMID 16461912 DOI: 10.1073/Pnas.0506281103  0.68
2006 Hess-Wilson JK, Boldison J, Weaver KE, Knudsen KE. Xenoestrogen action in breast cancer: impact on ER-dependent transcription and mitogenesis. Breast Cancer Research and Treatment. 96: 279-92. PMID 16328721 DOI: 10.1007/S10549-005-9082-Y  0.68
2005 Link KA, Burd CJ, Williams E, Marshall T, Rosson G, Henry E, Weissman B, Knudsen KE. BAF57 governs androgen receptor action and androgen-dependent proliferation through SWI/SNF Molecular and Cellular Biology. 25: 2200-2215. PMID 15743818 DOI: 10.1128/Mcb.25.6.2200-2215.2005  0.68
2005 Wetherill YB, Fisher NL, Staubach A, Danielsen M, de Vere White RW, Knudsen KE. Xenoestrogen action in prostate cancer: pleiotropic effects dependent on androgen receptor status. Cancer Research. 65: 54-65. PMID 15665279  0.68
2005 Petre-Draviam CE, Williams EB, Burd CJ, Gladden A, Moghadam H, Meller J, Diehl JA, Knudsen KE. A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene. 24: 431-44. PMID 15558026 DOI: 10.1038/Sj.Onc.1208200  0.68
2005 Burd CJ, Petre CE, Moghadam H, Wilson EM, Knudsen KE. Cyclin D1 binding to the androgen receptor (AR) NH2-terminal domain inhibits activation function 2 association and reveals dual roles for AR corepression. Molecular Endocrinology (Baltimore, Md.). 19: 607-20. PMID 15539430 DOI: 10.1210/Me.2004-0266  0.68
2004 Barnes-Ellerbe S, Knudsen KE, Puga A. 2,3,7,8-Tetrachlorodibenzo-p-dioxin blocks androgen-dependent cell proliferation of LNCaP cells through modulation of pRB phosphorylation. Molecular Pharmacology. 66: 502-11. PMID 15322241 DOI: 10.1124/Mol.104.000356  0.68
2003 Petre-Draviam CE, Cook SL, Burd CJ, Marshall TW, Wetherill YB, Knudsen KE. Specificity of cyclin D1 for androgen receptor regulation. Cancer Research. 63: 4903-13. PMID 12941814  0.68
2003 Marshall TW, Link KA, Petre-Draviam CE, Knudsen KE. Differential requirement of SWI/SNF for androgen receptor activity. The Journal of Biological Chemistry. 278: 30605-13. PMID 12775722 DOI: 10.1074/Jbc.M304582200  0.68
2002 Wetherill YB, Petre CE, Monk KR, Puga A, Knudsen KE. The xenoestrogen bisphenol A induces inappropriate androgen receptor activation and mitogenesis in prostatic adenocarcinoma cells. Molecular Cancer Therapeutics. 1: 515-24. PMID 12479269  0.68
2002 Strobeck MW, Reisman DN, Gunawardena RW, Betz BL, Angus SP, Knudsen KE, Kowalik TF, Weissman BE, Knudsen ES. Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling. The Journal of Biological Chemistry. 277: 4782-9. PMID 11719516 DOI: 10.1074/Jbc.M109532200  0.68
2002 Petre CE, Wetherill YB, Danielsen M, Knudsen KE. Cyclin D1: mechanism and consequence of androgen receptor co-repressor activity. The Journal of Biological Chemistry. 277: 2207-15. PMID 11714699 DOI: 10.1074/Jbc.M106399200  0.68
2000 Knudsen KE, Booth D, Naderi S, Sever-Chroneos Z, Fribourg AF, Hunton IC, Feramisco JR, Wang JY, Knudsen ES. RB-dependent S-phase response to DNA damage. Molecular and Cellular Biology. 20: 7751-63. PMID 11003670 DOI: 10.1128/Mcb.20.20.7751-7763.2000  0.68
2000 Strobeck MW, Knudsen KE, Fribourg AF, DeCristofaro MF, Weissman BE, Imbalzano AN, Knudsen ES. BRG-1 is required for RB-mediated cell cycle arrest. Proceedings of the National Academy of Sciences of the United States of America. 97: 7748-53. PMID 10884406 DOI: 10.1073/Pnas.97.14.7748  0.68
1999 Knudsen KE, Weber E, Arden KC, Cavenee WK, Feramisco JR, Knudsen ES. The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death. Oncogene. 18: 5239-45. PMID 10498874 DOI: 10.1038/Sj.Onc.1202910  0.68
1999 Knudsen KE, Fribourg AF, Strobeck MW, Blanchard JM, Knudsen ES. Cyclin A is a functional target of retinoblastoma tumor suppressor protein-mediated cell cycle arrest. The Journal of Biological Chemistry. 274: 27632-41. PMID 10488103 DOI: 10.1074/Jbc.274.39.27632  0.68
1999 Lenormand JL, Dellinger RW, Knudsen KE, Subramani S, Donoghue DJ. Speedy: a novel cell cycle regulator of the G2/M transition. The Embo Journal. 18: 1869-77. PMID 10202150 DOI: 10.1093/Emboj/18.7.1869  0.68
1995 Kanter-Smoler G, Knudsen KE, Jimenez G, Sunnerhagen P, Subramani S. Separation of phenotypes in mutant alleles of the Schizosaccharomyces pombe cell-cycle checkpoint gene rad1+. Molecular Biology of the Cell. 6: 1793-805. PMID 8590806 DOI: 10.1091/Mbc.6.12.1793  0.68
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