Joanna Floros - Publications

Pennsylvania State University, State College, PA, United States 
Animal Physiology Biology, Cell Biology, Immunology

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Phelps DS, Chinchilli VM, Weisz J, Yang L, Shearer D, Zhang X, Floros J. Differences in the alveolar macrophage toponome in humanized SP-A1 and SP-A2 transgenic mice. Jci Insight. PMID 33141765 DOI: 10.1172/jci.insight.141410  0.4
2020 Gandhi CK, Mikerov AN, Durrani F, Umstead TM, Hu S, Wang G, Phelps DS, Floros J. Impact of Ozone, Sex, and Gonadal Hormones on Bronchoalveolar Lavage Characteristics and Survival in SP-A KO Mice Infected with . Microorganisms. 8. PMID 32899781 DOI: 10.3390/microorganisms8091354  0.4
2020 Tekos F, Skaperda Z, Goutzourelas N, Phelps DS, Floros J, Kouretas D. The Importance of Redox Status in the Frame of Lifestyle Approaches and the Genetics of the Lung Innate Immune Molecules, SP-A1 and SP-A2, on Differential Outcomes of COVID-19 Infection. Antioxidants (Basel, Switzerland). 9. PMID 32854247 DOI: 10.3390/antiox9090784  0.4
2020 Phelps DS, Chinchilli VM, Weisz J, Shearer D, Zhang X, Floros J. Using toponomics to characterize phenotypic diversity in alveolar macrophages from male mice treated with exogenous SP-A1. Biomarker Research. 8: 5. PMID 32082572 DOI: 10.1186/s40364-019-0181-z  0.4
2019 Nalian A, Umstead TM, Yang CH, Silveyra P, Thomas NJ, Floros J, McCormack FX, Chroneos ZC. Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data. Frontiers in Immunology. 10: 2613. PMID 31781112 DOI: 10.3389/fimmu.2019.02613  0.4
2019 Noutsios GT, Thorenoor N, Zhang X, Phelps DS, Umstead TM, Durrani F, Floros J. Major Effect of Oxidative Stress on the Male, but Not Female, SP-A1 Type II Cell miRNome. Frontiers in Immunology. 10: 1514. PMID 31354704 DOI: 10.3389/fimmu.2019.01514  0.4
2019 Wang G, Umstead TM, Hu S, Mikerov AN, Phelps DS, Floros J. Differential Effects of Human SP-A1 and SP-A2 on the BAL Proteome and Signaling Pathways in Response to and Ozone Exposure. Frontiers in Immunology. 10: 561. PMID 30972061 DOI: 10.3389/fimmu.2019.00561  0.4
2018 MacNeill C, de Guzman GS, Lupo K, Umstead T, Phelps DS, Floros J. Anti-Inflammatory Effect of Surfactant Lipid in the Vaginal Mucosa: A Pilot Study. Journal of Lower Genital Tract Disease. PMID 30489432 DOI: 10.1097/LGT.0000000000000448  0.4
2018 Thorenoor N, Umstead TM, Zhang X, Phelps DS, Floros J. Survival of Surfactant Protein-A1 and SP-A2 Transgenic Mice After Infection, Exhibits Sex-, Gene-, and Variant Specific Differences; Treatment With Surfactant Protein Improves Survival. Frontiers in Immunology. 9: 2404. PMID 30459763 DOI: 10.3389/fimmu.2018.02404  0.4
2018 Thorenoor N, Zhang X, Umstead TM, Scott Halstead E, Phelps DS, Floros J. Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences. Respiratory Research. 19: 23. PMID 29394894 DOI: 10.1186/s12931-018-0723-1  0.4
2017 Noutsios GT, Thorenoor N, Zhang X, Phelps DS, Umstead TM, Durrani F, Floros J. SP-A2 contributes to miRNA-mediated sex differences in response to oxidative stress: pro-inflammatory, anti-apoptotic, and anti-oxidant pathways are involved. Biology of Sex Differences. 8: 37. PMID 29202868 DOI: 10.1186/s13293-017-0158-2  0.4
2016 Tsotakos N, Phelps DS, Yengo CM, Chinchilli VM, Floros J. Single-cell analysis reveals differential regulation of the alveolar macrophage actin cytoskeleton by surfactant proteins A1 and A2: implications of sex and aging. Biology of Sex Differences. 7: 18. PMID 26998217 DOI: 10.1186/s13293-016-0071-0  0.4
2015 Yang L, Carrillo M, Wu YM, DiAngelo SL, Silveyra P, Umstead TM, Halstead ES, Davies ML, Hu S, Floros J, McCormack FX, Christensen ND, Chroneos ZC. SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and Activation. Plos One. 10: e0126576. PMID 25965346 DOI: 10.1371/journal.pone.0126576  0.4
2014 Silveyra P, Chroneos ZC, DiAngelo SL, Thomas NJ, Noutsios GT, Tsotakos N, Howrylak JA, Umstead TM, Floros J. Knockdown of Drosha in human alveolar type II cells alters expression of SP-A in culture: a pilot study. Experimental Lung Research. 40: 354-66. PMID 25058539 DOI: 10.3109/01902148.2014.929757  0.4
2014 Phelps DS, Umstead TM, Floros J. Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome. Journal of Proteomics. 108: 427-44. PMID 24954098 DOI: 10.1016/j.jprot.2014.06.007  0.4
2014 Mikerov AN, Phelps DS, Gan X, Umstead TM, Haque R, Wang G, Floros J. Effect of ozone exposure and infection on bronchoalveolar lavage: sex differences in response patterns. Toxicology Letters. 230: 333-44. PMID 24769259 DOI: 10.1016/j.toxlet.2014.04.008  0.4
2014 Olmeda B, Umstead TM, Silveyra P, Pascual A, López-Barneo J, Phelps DS, Floros J, Pérez-Gil J. Effect of hypoxia on lung gene expression and proteomic profile: insights into the pulmonary surfactant response. Journal of Proteomics. 101: 179-91. PMID 24576641 DOI: 10.1016/j.jprot.2014.02.019  0.4
2013 Phelps DS, Umstead TM, Silveyra P, Hu S, Wang G, Floros J. Differences in the alveolar macrophage proteome in transgenic mice expressing human SP-A1 and SP-A2. Journal of Proteomics and Genomics Research. 1: 2-26. PMID 24729982 DOI: 10.14302/issn.2326-0793.jpgr-12-207  0.4
2013 Yang MY, Hilton MB, Seaman S, Haines DC, Nagashima K, Burks CM, Tessarollo L, Ivanova PT, Brown HA, Umstead TM, Floros J, Chroneos ZC, St Croix B. Essential regulation of lung surfactant homeostasis by the orphan G protein-coupled receptor GPR116. Cell Reports. 3: 1457-64. PMID 23684610 DOI: 10.1016/j.celrep.2013.04.019  0.4
2012 Phelps DS, Umstead TM, Floros J. Sex differences in the response of the alveolar macrophage proteome to treatment with exogenous surfactant protein-A. Proteome Science. 10: 44. PMID 22824420 DOI: 10.1186/1477-5956-10-44  0.4
2012 Macneill C, de Guzman G, Sousa GE, Umstead TM, Phelps DS, Floros J, Ahn K, Weisz J. Cyclic changes in the level of the innate immune molecule, surfactant protein-a, and cytokines in vaginal fluid. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 68: 244-50. PMID 22672628 DOI: 10.1111/j.1600-0897.2012.01155.x  0.4
2012 Durrani F, Phelps DS, Weisz J, Silveyra P, Hu S, Mikerov AN, Floros J. Gonadal hormones and oxidative stress interaction differentially affects survival of male and female mice after lung Klebsiella Pneumoniae infection Experimental Lung Research. 38: 165-172. PMID 22394250 DOI: 10.3109/01902148.2011.654045  0.4
2012 Mikerov AN, Hu S, Durrani F, Gan X, Wang G, Umstead TM, Phelps DS, Floros J. Impact of sex and ozone exposure on the course of pneumonia in wild type and SP-A (-/-) mice. Microbial Pathogenesis. 52: 239-49. PMID 22285567 DOI: 10.1016/j.micpath.2012.01.005  0.4
2011 Phelps DS, Umstead TM, Quintero OA, Yengo CM, Floros J. In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement. Proteome Science. 9: 67. PMID 22035134 DOI: 10.1186/1477-5956-9-67  0.4
2011 Mikerov AN, Cooper TK, Wang G, Hu S, Umstead TM, Phelps DS, Floros J. Histopathologic evaluation of lung and extrapulmonary tissues show sex differences in Klebsiella pneumoniae - infected mice under different exposure conditions. International Journal of Physiology, Pathophysiology and Pharmacology. 3: 176-90. PMID 21941609  0.4
2010 Ali M, Umstead TM, Haque R, Mikerov AN, Freeman WM, Floros J, Phelps DS. Differences in the BAL proteome after Klebsiella pneumoniae infection in wild type and SP-A-/- mice. Proteome Science. 8: 34. PMID 20565803 DOI: 10.1186/1477-5956-8-34  0.4
2009 Haque R, Umstead TM, Ahn K, Phelps DS, Floros J. Effect of low doses of lipopolysaccharide prior to ozone exposure on bronchoalveolar lavage: Differences between wild type and surfactant protein A-deficient mice. Pneumon. 22: 143-155. PMID 21278811  0.4
2009 Undar A, Pauliks L, Clark JB, Zahn J, Rosenberg G, Kunselman AR, Sun Q, Pekkan K, Saliba K, Carney E, Thomas N, Freeman W, Vrana K, El-Banayosy A, Ural SH, ... ... Floros J, et al. Penn State Hershey--center for pediatric cardiovascular research. Artificial Organs. 33: 883-7. PMID 20021467 DOI: 10.1111/j.1525-1594.2009.00889.x  0.4
2009 Haque R, Umstead TM, Freeman WM, Floros J, Phelps DS. The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome. Proteome Science. 7: 12. PMID 19323824 DOI: 10.1186/1477-5956-7-12  0.4
2008 Mikerov AN, Haque R, Gan X, Guo X, Phelps DS, Floros J. Ablation of SP-A has a negative impact on the susceptibility of mice to Klebsiella pneumoniae infection after ozone exposure: sex differences. Respiratory Research. 9: 77. PMID 19055785 DOI: 10.1186/1465-9921-9-77  0.4
2008 Mikerov AN, Gan X, Umstead TM, Miller L, Chinchilli VM, Phelps DS, Floros J. Sex differences in the impact of ozone on survival and alveolar macrophage function of mice after Klebsiella pneumoniae infection. Respiratory Research. 9: 24. PMID 18307797 DOI: 10.1186/1465-9921-9-24  0.4
2008 Mikerov AN, Umstead TM, Gan X, Huang W, Guo X, Wang G, Phelps DS, Floros J. Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L121-30. PMID 17981957 DOI: 10.1152/ajplung.00288.2007  0.4
2008 Pavlovic J, Floros J, Phelps DS, Wigdahl B, Welsh P, Weisz J, Shearer DA, Leure du Pree A, Myers R, Howett MK. Differentiation of xenografted human fetal lung parenchyma. Early Human Development. 84: 181-93. PMID 17555893 DOI: 10.1016/j.earlhumdev.2007.04.002  0.4
2007 Stagos D, Umstead TM, Phelps DS, Skaltsounis L, Haroutounian S, Floros J, Kouretas D. Inhibition of ozone-induced SP-A oxidation by plant polyphenols. Free Radical Research. 41: 357-66. PMID 17364965 DOI: 10.1080/10715760601064714  0.4
2007 Haque R, Umstead TM, Ponnuru P, Guo X, Hawgood S, Phelps DS, Floros J. Role of surfactant protein-A (SP-A) in lung injury in response to acute ozone exposure of SP-A deficient mice. Toxicology and Applied Pharmacology. 220: 72-82. PMID 17307210 DOI: 10.1016/j.taap.2006.12.017  0.4
2007 Mikerov AN, Wang G, Umstead TM, Zacharatos M, Thomas NJ, Phelps DS, Floros J. Surfactant protein A2 (SP-A2) variants expressed in CHO cells stimulate phagocytosis of Pseudomonas aeruginosa more than do SP-A1 variants. Infection and Immunity. 75: 1403-12. PMID 17220308 DOI: 10.1128/IAI.01341-06  0.4
2007 Tagaram HR, Wang G, Umstead TM, Mikerov AN, Thomas NJ, Graff GR, Hess JC, Thomassen MJ, Kavuru MS, Phelps DS, Floros J. Characterization of a human surfactant protein A1 (SP-A1) gene-specific antibody; SP-A1 content variation among individuals of varying age and pulmonary health. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L1052-63. PMID 17189324 DOI: 10.1152/ajplung.00249.2006  0.4
2005 Janic B, Umstead TM, Phelps DS, Floros J. Modulatory effects of ozone on THP-1 cells in response to SP-A stimulation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L317-25. PMID 15466251 DOI: 10.1152/ajplung.00125.2004  0.4
2005 Mikerov AN, Umstead TM, Huang W, Liu W, Phelps DS, Floros J. SP-A1 and SP-A2 variants differentially enhance association of Pseudomonas aeruginosa with rat alveolar macrophages. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L150-8. PMID 15377498 DOI: 10.1152/ajplung.00135.2004  0.4
2004 Ding J, Umstead TM, Floros J, Phelps DS. Factors affecting SP-A-mediated phagocytosis in human monocytic cell lines. Respiratory Medicine. 98: 637-50. PMID 15250230  0.4
2004 Wang G, Bates-Kenney SR, Tao JQ, Phelps DS, Floros J. Differences in biochemical properties and in biological function between human SP-A1 and SP-A2 variants, and the impact of ozone-induced oxidation. Biochemistry. 43: 4227-39. PMID 15065867 DOI: 10.1021/bi036023i  0.4
2004 MacNeill C, Umstead TM, Phelps DS, Lin Z, Floros J, Shearer DA, Weisz J. Surfactant protein A, an innate immune factor, is expressed in the vaginal mucosa and is present in vaginal lavage fluid Immunology. 111: 91-99. PMID 14678203 DOI: 10.1111/j.1365-2567.2004.01782.x  0.4
2004 Huang W, Wang G, Phelps DS, Al-Mondhiry H, Floros J. Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: effect of ozone-induced SP-A oxidation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L546-53. PMID 14617519 DOI: 10.1152/ajplung.00267.2003  0.4
2003 Selman M, Lin HM, Montaño M, Jenkins AL, Estrada A, Lin Z, Wang G, DiAngelo SL, Guo X, Umstead TM, Lang CM, Pardo A, Phelps DS, Floros J. Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis. Human Genetics. 113: 542-50. PMID 13680361 DOI: 10.1007/s00439-003-1015-4  0.4
2003 Janic B, Umstead TM, Phelps DS, Floros J. An in vitro cell model system for the study of the effects of ozone and other gaseous agents on phagocytic cells. Journal of Immunological Methods. 272: 125-34. PMID 12505718  0.4
2002 Umstead TM, Phelps DS, Wang G, Floros J, Tarkington BK. In vitro exposure of proteins to ozone. Toxicology Mechanisms and Methods. 12: 1-16. PMID 20597812 DOI: 10.1080/15376510209167932  0.4
2002 Huang W, Wang G, Phelps DS, Al-Mondhiry H, Floros J. Combined SP-A-bleomycin effect on cytokines by THP-1 cells: impact of surfactant lipids on this effect. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L94-L102. PMID 12060565 DOI: 10.1152/ajplung.00434.2001  0.4
2002 Wang G, Umstead TM, Phelps DS, Al-Mondhiry H, Floros J. The effect of ozone exposure on the ability of human surfactant protein a variants to stimulate cytokine production. Environmental Health Perspectives. 110: 79-84. PMID 11781168  0.4
2000 Wang G, Phelps DS, Umstead TM, Floros J. Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line. American Journal of Physiology. Lung Cellular and Molecular Physiology. 278: L946-54. PMID 10781424 DOI: 10.1152/AJPLUNG.2000.278.5.L946  0.4
1997 Koptides M, Umstead TM, Floros J, Phelps DS. Surfactant protein A activates NF-kappa B in the THP-1 monocytic cell line. The American Journal of Physiology. 273: L382-8. PMID 9277450 DOI: 10.1152/ajplung.1997.273.2.L382  0.4
1992 Guttentag SH, Phelps DS, Stenzel W, Warshaw JB, Floros J. Surfactant protein A expression is delayed in fetuses of streptozotocin-treated rats. The American Journal of Physiology. 262: L489-94. PMID 1533098 DOI: 10.1152/ajplung.1992.262.4.L489  0.4
1992 Guttentag SH, Phelps DS, Warshaw JB, Floros J. Delayed hydrophobic surfactant protein (SP-B, SP-C) expression in fetuses of streptozotocin-treated rats. American Journal of Respiratory Cell and Molecular Biology. 7: 190-7. PMID 1386745 DOI: 10.1165/ajrcmb/7.2.190  0.4
1991 Phelps DS, Floros J. Dexamethasone in vivo raises surfactant protein B mRNA in alveolar and bronchiolar epithelium. The American Journal of Physiology. 260: L146-52. PMID 1996658 DOI: 10.1152/ajplung.1991.260.2.L146  0.4
1991 Phelps DS, Floros J. Localization of pulmonary surfactant proteins using immunohistochemistry and tissue in situ hybridization. Experimental Lung Research. 17: 985-95. PMID 1769356 DOI: 10.3109/01902149109064330  0.4
1991 Floros J, Phelps DS, deMello DE, Longmate J, Harding H, Benson B, White T. The utility of postmortem lung for RNA studies; variability and correlation of the expression of surfactant proteins in human lung. Experimental Lung Research. 17: 91-104. PMID 1707362 DOI: 10.3109/01902149109063284  0.4
1989 Floros J, Phelps DS, Harding HP, Church S, Ware J. Postnatal stimulation of rat surfactant protein A synthesis by dexamethasone. The American Journal of Physiology. 257: L137-43. PMID 2475036 DOI: 10.1152/ajplung.1989.257.2.L137  0.4
1988 Chida S, Phelps DS, Cordle C, Soll R, Floros J, Taeusch HW. Surfactant-associated proteins in tracheal aspirates of infants with respiratory distress syndrome after surfactant therapy. The American Review of Respiratory Disease. 137: 943-7. PMID 3355003 DOI: 10.1164/ajrccm/137.4.943  0.4
1988 Phelps DS, Floros J. Localization of surfactant protein synthesis in human lung by in situ hybridization. The American Review of Respiratory Disease. 137: 939-42. PMID 3355002 DOI: 10.1164/ajrccm/137.4.939  0.4
1988 Phelps DS, Floros J. Proline hydroxylation alters the electrophoretic mobility of pulmonary surfactant-associated protein A. Electrophoresis. 9: 231-3. PMID 3234361 DOI: 10.1002/elps.1150090508  0.4
1986 Phelps DS, Floros J, Taeusch HW. Post-translational modification of the major human surfactant-associated proteins. The Biochemical Journal. 237: 373-7. PMID 3800894 DOI: 10.1042/bj2370373  0.4
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