J Frederic Mushinski - Publications

Affiliations: 
University of Maryland, College Park, College Park, MD 
Area:
Molecular Biology, Cell Biology

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 LeGrand J, Park ES, Wang H, Gupta S, Owens JD, Nelson PJ, DuBois W, Bair T, Janz S, Mushinski JF. Global gene expression profiling in mouse plasma cell tumor precursor and bystander cells reveals potential intervention targets for plasma cell neoplasia. Blood. 119: 1018-28. PMID 22147894 DOI: 10.1182/Blood-2011-06-363887  0.354
2011 Romanova LY, Mushinski JF. Central role of paxillin phosphorylation in regulation of LFA-1 integrins activity and lymphocyte migration. Cell Adhesion & Migration. 5: 457-62. PMID 22274710 DOI: 10.4161/cam.5.6.18219  0.328
2010 Romanova LY, Holmes G, Bahte SK, Kovalchuk AL, Nelson PJ, Ward Y, Gueler F, Mushinski JF. Phosphorylation of paxillin at threonine 538 by PKCdelta regulates LFA1-mediated adhesion of lymphoid cells. Journal of Cell Science. 123: 1567-77. PMID 20388733 DOI: 10.1242/Jcs.060996  0.489
2009 Mushinski JF, Nguyen P, Stevens LM, Khanna C, Lee S, Chung EJ, Lee MJ, Kim YS, Linehan WM, Horisberger MA, Trepel JB. Inhibition of tumor cell motility by the interferon-inducible GTPase MxA. The Journal of Biological Chemistry. 284: 15206-14. PMID 19297326 DOI: 10.1074/Jbc.M806324200  0.351
2007 Park ES, Shaughnessy JD, Gupta S, Wang H, Lee JS, Woo HG, Zhan F, Owens JD, Potter M, Janz S, Mushinski JF. Gene expression profiling reveals different pathways related to Abl and other genes that cooperate with c-Myc in a model of plasma cell neoplasia. Bmc Genomics. 8: 302. PMID 17764563 DOI: 10.1186/1471-2164-8-302  0.343
2005 Thiefes A, Wolter S, Mushinski JF, Hoffmann E, Dittrich-Breiholz O, Graue N, Dörrie A, Schneider H, Wirth D, Luckow B, Resch K, Kracht M. Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes. The Journal of Biological Chemistry. 280: 27728-41. PMID 15837794 DOI: 10.1074/Jbc.M411657200  0.44
2005 Sung SP, Joong SK, Tessarollo L, Owens JD, Peng L, Seong SH, Seung TC, Torrey TA, Cheung WC, Polakiewicz RD, McNeil N, Ried T, Mushinski JF, Morse HC, Janz S. Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice Cancer Research. 65: 1306-1315. PMID 15735016 DOI: 10.1158/0008-5472.Can-04-0268  0.375
2004 Romanova LY, Hashimoto S, Chay KO, Blagosklonny MV, Sabe H, Mushinski JF. Phosphorylation of paxillin tyrosines 31 and 118 controls polarization and motility of lymphoid cells and is PMA-sensitive. Journal of Cell Science. 117: 3759-68. PMID 15252114 DOI: 10.1242/Jcs.01206  0.468
2004 Wang QJ, Lu G, Schlapkohl WA, Goerke A, Larsson C, Mischak H, Blumberg PM, Mushinski JF. The V5 domain of protein kinase C plays a critical role in determining the isoform-specific localization, translocation, and biological function of protein kinase C-delta and -epsilon. Molecular Cancer Research : McR. 2: 129-40. PMID 14985469  0.608
2003 Mai S, Mushinski JF. c-Myc-induced genomic instability. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 22: 179-99. PMID 14529093 DOI: 10.1615/Jenvpathtoxoncol.V22.I3.30  0.348
2002 Goerke A, Sakai N, Gutjahr E, Schlapkohl WA, Mushinski JF, Haller H, Kolch W, Saito N, Mischak H. Induction of apoptosis by protein kinase C delta is independent of its kinase activity. The Journal of Biological Chemistry. 277: 32054-62. PMID 12055197 DOI: 10.1074/Jbc.M203734200  0.6
2002 Chay KO, Park SS, Mushinski JF. Linkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytes. The Journal of Biological Chemistry. 277: 14521-9. PMID 11825902 DOI: 10.1074/Jbc.M111639200  0.36
2002 Wolter S, Mushinski JF, Saboori AM, Resch K, Kracht M. Inducible expression of a constitutively active mutant of mitogen-activated protein kinase kinase 7 specifically activates c-JUN NH2-terminal protein kinase, alters expression of at least nine genes, and inhibits cell proliferation. The Journal of Biological Chemistry. 277: 3576-84. PMID 11714698 DOI: 10.1074/Jbc.M105800200  0.565
2001 Fatma S, Mushinski JF, Bansal SK. Multiple isoforms of protein kinase C in lymphocytes and airway smooth muscle of guinea pig. Indian Journal of Biochemistry & Biophysics. 38: 280-4. PMID 11811627  0.353
2000 Kim JS, Pirnia F, Choi YH, Nguyen PM, Knepper B, Tsokos M, Schulte TW, Birrer MJ, Blagosklonny MV, Schaefer O, Mushinski JF, Trepel JB. Lovastatin induces apoptosis in a primitive neuroectodermal tumor cell line in association with RB down-regulation and loss of the G1 checkpoint. Oncogene. 19: 6082-90. PMID 11146561 DOI: 10.1038/Sj.Onc.1204008  0.386
2000 Dammeier S, Lovric J, Eulitz M, Kolch W, Mushinski JF, Mischak H. Identification of the smooth muscle-specific protein, sm22, as a novel protein kinase C substrate using two-dimensional gel electrophoresis and mass spectrometry. Electrophoresis. 21: 2443-53. PMID 10939458 DOI: 10.1002/1522-2683(20000701)21:12<2443::Aid-Elps2443>3.0.Co;2-6  0.509
1999 Mai S, Hanley-Hyde J, Rainey GJ, Kuschak TI, Paul JT, Littlewood TD, Mischak H, Stevens LM, Henderson DW, Mushinski JF. Chromosomal and extrachromosomal instability of the cyclin D2 gene is induced by Myc overexpression. Neoplasia (New York, N.Y.). 1: 241-52. PMID 10935479 DOI: 10.1038/Sj.Neo.7900030  0.392
1999 Kuschak TI, Taylor C, McMillan-Ward E, Israels S, Henderson DW, Mushinski JF, Wright JA, Mai S. The ribonucleotide reductase R2 gene is a non-transcribed target of c-Myc-induced genomic instability. Gene. 238: 351-65. PMID 10570963 DOI: 10.1016/S0378-1119(99)00341-8  0.371
1999 Romanova LY, Alexandrov IA, Blagosklonny MV, Nordan RP, Garfield S, Acs P, Nguyen P, Trepel J, Blumberg PM, Mushinski JF. Regulation of actin cytoskeleton in lymphocytes: PKC-delta disrupts IL-3-induced membrane ruffles downstream of Rac1. Journal of Cellular Physiology. 179: 157-69. PMID 10199555 DOI: 10.1002/(Sici)1097-4652(199905)179:2<157::Aid-Jcp6>3.0.Co;2-4  0.327
1998 Chang YY, Kim SJ, Park TK, Kang SS, Ha MJ, Mushinski JF, Chun JS. Modulation of MAP kinase signaling and growth characteristics by the overexpression of protein kinase C in NIH3T3 cells. Biochemistry and Molecular Biology International. 45: 1139-48. PMID 9762412 DOI: 10.1080/15216549800203362  0.398
1998 Maucher C, Weissinger EM, Kremmer E, Baccarini M, Procyk K, Henderson DW, Wolff L, Kolch W, Kaspers B, Mushinski JF, Mischak H. Activation of bcl-2 suppressible 40 and 44 kDa p38-like kinases during apoptosis of early and late B lymphocytic cell lines Febs Letters. 427: 29-35. PMID 9613594 DOI: 10.1016/S0014-5793(98)00387-1  0.506
1998 Romanova LY, Alexandrov IA, Nordan RP, Blagosklonny MV, Mushinski JF. Cross-talk between protein kinase C-alpha (PKC-alpha) and -delta (PKC-delta): PKC-alpha elevates the PKC-delta protein level, altering its mRNA transcription and degradation. Biochemistry. 37: 5558-65. PMID 9548940 DOI: 10.1021/bi9731807  0.351
1998 Wang QJ, Acs P, Goodnight J, Blumberg PM, Mischak H, Mushinski JF. The catalytic domain of PKC-epsilon, in reciprocal PKC-delta and -epsilon chimeras, is responsible for conferring tumorgenicity to NIH3T3 cells, whereas both regulatory and catalytic domains of PKC-epsilon contribute to in vitro transformation. Oncogene. 16: 53-60. PMID 9467942 DOI: 10.1038/sj.onc.1201507  0.451
1997 Acs P, Wang QJ, Bögi K, Marquez AM, Lorenzo PS, Bíró T, Szállási Z, Mushinski JF, Blumberg PM. Both the catalytic and regulatory domains of protein kinase C chimeras modulate the proliferative properties of NIH 3T3 cells. The Journal of Biological Chemistry. 272: 28793-9. PMID 9353351 DOI: 10.1074/Jbc.272.45.28793  0.39
1997 Wang QJ, Acs P, Goodnight J, Giese T, Blumberg PM, Mischak H, Mushinski JF. The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon chimeras mediates phorbol ester-induced macrophage differentiation of mouse promyelocytes. The Journal of Biological Chemistry. 272: 76-82. PMID 8995230 DOI: 10.1074/JBC.272.1.76  0.492
1996 Schulte TW, Blagosklonny MV, Romanova L, Mushinski JF, Monia BP, Johnston JF, Nguyen P, Trepel J, Neckers LM. Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway. Molecular and Cellular Biology. 16: 5839-45. PMID 8816498  0.396
1996 Weissinger EM, Byrd LG, Henderson DW, Mushinski JF. Overexpression of v-abl uniquely cooperates with c-myc dysregulation in induction of plasma cell tumors, bypassing the need for T-lymphocytic help and overcoming T-lymphocytic interference International Journal of Cancer. 67: 142-147. PMID 8690515 DOI: 10.1002/(Sici)1097-0215(19960703)67:1<142::Aid-Ijc23>3.0.Co;2-F  0.367
1996 Kieser A, Seitz T, Adler HS, Coffer P, Kremmer E, Crespo P, Gutkind JS, Henderson DW, Mushinski JF, Kolch W, Mischak H. Protein kinase C-zeta reverts v-raf transformation of NIH-3T3 cells. Genes & Development. 10: 1455-66. PMID 8666230 DOI: 10.1101/GAD.10.12.1455  0.361
1996 Morawetz R, Lendenfeld T, Mischak H, Mühlbauer M, Gruber F, Goodnight J, de Graaff LH, Visser J, Mushinski JF, Kubicek CP. Cloning and characterisation of genes (pkc1 and pkcA) encoding protein kinase C homologues from Trichoderma reesei and Aspergillus niger. Molecular & General Genetics : Mgg. 250: 17-28. PMID 8569684  0.461
1995 Goodnight JA, Mischak H, Kolch W, Mushinski JF. Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes. The Journal of Biological Chemistry. 270: 9991-10001. PMID 7730383 DOI: 10.1074/Jbc.270.17.9991  0.51
1995 Kieser A, Goodnight J, Kölch W, Mischak H, Mushinski JF. Identification of the primary growth response gene, ST2/T1, as a gene whose expression is differentially regulated by different protein kinase C isozymes. Febs Letters. 372: 189-93. PMID 7556667 DOI: 10.1016/0014-5793(95)00975-F  0.401
1994 Lehel C, Olah Z, Mischak H, Mushinski JF, Anderson WB. Overexpressed protein kinase C-delta and -epsilon subtypes in NIH 3T3 cells exhibit differential subcellular localization and differential regulation of sodium-dependent phosphate uptake. The Journal of Biological Chemistry. 269: 4761-6. PMID 8106444  0.402
1994 Mushinski JF, Goodnight J, Rudikoff E, Morse HC, Langdon WY. Expression of c-cbl proto-oncogene is modulated during differentiation but not during induction of proliferation. Oncogene. 9: 2489-97. PMID 8058312  0.375
1994 Goodnight J, Mischak H, Mushinski JF. Association of elevated levels of protein kinase C-zeta mRNA and protein with murine B-lymphocytic neoplasia. Molecular Carcinogenesis. 11: 131-7. PMID 7945801 DOI: 10.1002/Mc.2940110303  0.49
1994 Goodnight J, Mischak H, Mushinski JF. Selective involvement of protein kinase C isozymes in differentiation and neoplastic transformation. Advances in Cancer Research. 64: 159-209. PMID 7879658  0.422
1994 Li W, Mischak H, Yu JC, Wang LM, Mushinski JF, Heidaran MA, Pierce JH. Tyrosine phosphorylation of protein kinase C-delta in response to its activation. The Journal of Biological Chemistry. 269: 2349-52. PMID 7507923  0.488
1993 Mischak H, Goodnight JA, Kolch W, Martiny-Baron G, Schaechtle C, Kazanietz MG, Blumberg PM, Pierce JH, Mushinski JF. Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. The Journal of Biological Chemistry. 268: 6090-6. PMID 8454583  0.44
1993 Ozawa K, Szallasi Z, Kazanietz MG, Blumberg PM, Mischak H, Mushinski JF, Beaven MA. Ca(2+)-dependent and Ca(2+)-independent isozymes of protein kinase C mediate exocytosis in antigen-stimulated rat basophilic RBL-2H3 cells. Reconstitution of secretory responses with Ca2+ and purified isozymes in washed permeabilized cells. The Journal of Biological Chemistry. 268: 1749-56. PMID 8420951  0.31
1993 Mischak H, Pierce JH, Goodnight J, Kazanietz MG, Blumberg PM, Mushinski JF. Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-alpha and -delta and not by protein kinase C-beta II, -epsilon, -zeta, and -eta. The Journal of Biological Chemistry. 268: 20110-5. PMID 8376369  0.416
1993 Kazanietz MG, Areces LB, Bahador A, Mischak H, Goodnight J, Mushinski JF, Blumberg PM. Characterization of ligand and substrate specificity for the calcium-dependent and calcium-independent protein kinase C isozymes. Molecular Pharmacology. 44: 298-307. PMID 8355667  0.308
1993 Huppi K, Siwarski D, Shaughnessy JD, Mushinski JF. Co-amplification of c-myc/pvt-1 in immortalized mouse B-lymphocytic cell lines results in a novel pvt-1/AJ-1 transcript. International Journal of Cancer. 53: 493-8. PMID 8094075 DOI: 10.1002/Ijc.2910530323  0.358
1992 Goodnight J, Kazanietz MG, Blumberg PM, Mushinski JF, Mischak H. The cDNA sequence, expression pattern and protein characteristics of mouse protein kinase C-zeta. Gene. 122: 305-11. PMID 1487145 DOI: 10.1016/0378-1119(92)90219-F  0.353
1992 Hanley-Hyde J, Mushinski JF, Sadofsky M, Huppi K, Krall M, Kozak CA, Mock B. Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics. 13: 1018-30. PMID 1387105 DOI: 10.1016/0888-7543(92)90015-K  0.359
1992 Dlugosz AA, Mischak H, Mushinski JF, Yuspa SH. Transcripts encoding protein kinase C-alpha, -delta, -epsilon, -zeta, and -eta are expressed in basal and differentiating mouse keratinocytes in vitro and exhibit quantitative changes in neoplastic cells. Molecular Carcinogenesis. 5: 286-92. PMID 1379814 DOI: 10.1002/Mc.2940050409  0.406
1991 Mischak H, Kolch W, Goodnight J, Davidson WF, Rapp U, Rose-John S, Mushinski JF. Expression of protein kinase C genes in hemopoietic cells is cell-type- and B cell-differentiation stage specific. Journal of Immunology (Baltimore, Md. : 1950). 147: 3981-7. PMID 1940380  0.322
1991 Mischak H, Bodenteich A, Kolch W, Goodnight J, Hofer F, Mushinski JF. Mouse protein kinase C-delta, the major isoform expressed in mouse hemopoietic cells: sequence of the cDNA, expression patterns, and characterization of the protein. Biochemistry. 30: 7925-31. PMID 1868068  0.46
1991 Kochel T, Mushinski JF, Rice NR. The v-rel and c-rel proteins exist in high molecular weight complexes in avian and murine cells. Oncogene. 6: 615-26. PMID 1851550  0.334
1990 Shen-Ong GL, Skurla RM, Owens JD, Mushinski JF. Alternative splicing of RNAs transcribed from the human c-myb gene. Molecular and Cellular Biology. 10: 2715-22. PMID 2188096  0.305
1987 Mushinski JF, Davidson WF, Morse HC. Activation of cellular oncogenes in human and mouse leukemia-lymphomas: spontaneous and induced oncogene expression in murine B lymphocytic neoplasms. Cancer Investigation. 5: 345-68. PMID 3311314 DOI: 10.1080/07357908709170109  0.345
1987 Gurfinkel N, Unger T, Givol D, Mushinski JF. Expression of the bcl-2 gene in mouse B lymphocytic cell lines is differentiation stage specific European Journal of Immunology. 17: 567-570. PMID 3106072 DOI: 10.1002/Eji.1830170421  0.346
1986 Wolff L, Mushinski JF, Gilboa E, Morse HC. Induction of hematopoietic tumors using a viral construct containing c-myc cDNA from normal mouse spleen Current Topics in Microbiology and Immunology. 132: 33-39. PMID 3024920 DOI: 10.1007/978-3-642-71562-4_5  0.331
1986 Klinman DM, Steinberg AD, Mushinski JF. Effect of cyclophosphamide therapy on oncogene expression in angioimmunoblastic lymphadenopathy. Lancet (London, England). 2: 1055-8. PMID 2877222 DOI: 10.1016/S0140-6736(86)90464-2  0.324
1980 Mushinski JF, Koziol JA, Marini M. Cluster analysis of aminoacyl-tRNAs from mouse plasmacytomas correlates chromatographic profiles with myeloma protein similarity, clonal origin of tumor lines, and the neoplastic nature of the tissues Journal of Theoretical Biology. 85: 507-521. PMID 6777607 DOI: 10.1016/0022-5193(80)90324-0  0.337
1979 Marini M, Mushinski JF. Transfer ribonucleic acids from eleven immunoglobulin- -secreting mouse plasmacytomas. Constant and variable chromatographic profiles compared with the myeloma protein sequences. Biochimica Et Biophysica Acta. 562: 252-270. PMID 255344 DOI: 10.1016/0005-2787(79)90171-0  0.319
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