Janus J. Bieker - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Molecular Biology, Cell Biology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Gnanapragasam MN, Bieker JJ. Orchestration of late events in erythropoiesis by KLF1/EKLF. Current Opinion in Hematology. PMID 28157724 DOI: 10.1097/Moh.0000000000000327  0.343
2017 Planutis A, Xue L, Trainor CD, Dangeti M, Gillinder K, Siatecka M, Nebor D, Peters LL, Perkins AC, Bieker JJ. Neomorphic effects of the neonatal anemia (Nan-Eklf) mutation contribute to deficits throughout development. Development (Cambridge, England). 144: 430-440. PMID 28143845 DOI: 10.1242/Dev.145656  0.357
2016 Gillinder KR, Ilsley MD, Nébor D, Sachidanandam R, Lajoie M, Magor GW, Tallack MR, Bailey T, Landsberg MJ, Mackay JP, Parker MW, Miles LA, Graber JH, Peters LL, Bieker JJ, et al. Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability. Nucleic Acids Research. PMID 27899603 DOI: 10.1093/nar/gkw1014  0.33
2016 Gnanapragasam MN, McGrath KE, Catherman S, Xue L, Palis J, Bieker JJ. EKLF/KLF1-regulated cell cycle exit is essential for erythroblast enucleation. Blood. PMID 27480112 DOI: 10.1182/Blood-2016-03-706671  0.351
2015 Liang R, Campreciós G, Kou Y, McGrath K, Nowak R, Catherman S, Bigarella CL, Rimmelé P, Zhang X, Gnanapragasam MN, Bieker JJ, Papatsenko D, Ma'ayan A, Bresnick E, Fowler V, et al. A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis. Plos Genetics. 11: e1005526. PMID 26452208 DOI: 10.1371/Journal.Pgen.1005526  0.356
2015 Lohmann F, Dangeti M, Soni S, Chen X, Planutis A, Baron MH, Choi K, Bieker JJ. The DEK oncoprotein is a critical component of the EKLF/KLF1 enhancer in erythroid cells. Molecular and Cellular Biology. PMID 26303528 DOI: 10.1128/Mcb.00382-15  0.463
2015 Siatecka M, Soni S, Planutis A, Bieker JJ. Transcriptional activity of erythroid Kruppel-like factor (EKLF/KLF1) modulated by PIAS3 (protein inhibitor of activated STAT3). The Journal of Biological Chemistry. 290: 9929-40. PMID 25713074 DOI: 10.1074/Jbc.M114.610246  0.468
2015 Yien YY, Gnanapragasam MN, Gupta R, Rivella S, Bieker JJ. Alternative splicing of EKLF/KLF1 in murine primary erythroid tissues. Experimental Hematology. 43: 65-70. PMID 25283745 DOI: 10.1016/J.Exphem.2014.08.007  0.441
2014 Soni S, Pchelintsev N, Adams PD, Bieker JJ. Transcription factor EKLF (KLF1) recruitment of the histone chaperone HIRA is essential for β-globin gene expression. Proceedings of the National Academy of Sciences of the United States of America. 111: 13337-42. PMID 25197097 DOI: 10.1073/Pnas.1405422111  0.402
2014 Xue L, Galdass M, Gnanapragasam MN, Manwani D, Bieker JJ. Extrinsic and intrinsic control by EKLF (KLF1) within a specialized erythroid niche. Development (Cambridge, England). 141: 2245-54. PMID 24866116 DOI: 10.1242/Dev.103960  0.35
2014 Varricchio L, Dell'Aversana C, Nebbioso A, Migliaccio G, Altucci L, Mai A, Grazzini G, Bieker JJ, Migliaccio AR. Identification of NuRSERY, a new functional HDAC complex composed by HDAC5, GATA1, EKLF and pERK present in human erythroid cells. The International Journal of Biochemistry & Cell Biology. 50: 112-22. PMID 24594363 DOI: 10.1016/J.Biocel.2014.02.019  0.302
2013 Yien YY, Bieker JJ. EKLF/KLF1, a tissue-restricted integrator of transcriptional control, chromatin remodeling, and lineage determination. Molecular and Cellular Biology. 33: 4-13. PMID 23090966 DOI: 10.1128/Mcb.01058-12  0.369
2012 Yien YY, Bieker JJ. Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cβ. The Journal of Biological Chemistry. 287: 15193-204. PMID 22393050 DOI: 10.1074/Jbc.M112.350496  0.486
2011 Mas C, Lussier-Price M, Soni S, Morse T, Arseneault G, Di Lello P, Lafrance-Vanasse J, Bieker JJ, Omichinski JG. Structural and functional characterization of an atypical activation domain in erythroid Kruppel-like factor (EKLF). Proceedings of the National Academy of Sciences of the United States of America. 108: 10484-9. PMID 21670263 DOI: 10.1073/Pnas.1017029108  0.432
2011 Siatecka M, Bieker JJ. The multifunctional role of EKLF/KLF1 during erythropoiesis. Blood. 118: 2044-54. PMID 21613252 DOI: 10.1182/Blood-2011-03-331371  0.399
2010 Chen J, Peterson KR, Iancu-Rubin C, Bieker JJ. Design of embedded chimeric peptide nucleic acids that efficiently enter and accurately reactivate gene expression in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 16846-51. PMID 20837550 DOI: 10.1073/Pnas.0912896107  0.318
2010 Siatecka M, Sahr KE, Andersen SG, Mezei M, Bieker JJ, Peters LL. Severe anemia in the Nan mutant mouse caused by sequence-selective disruption of erythroid Kruppel-like factor. Proceedings of the National Academy of Sciences of the United States of America. 107: 15151-6. PMID 20696915 DOI: 10.1073/Pnas.1004996107  0.355
2010 Siatecka M, Lohmann F, Bao S, Bieker JJ. EKLF directly activates the p21WAF1/CIP1 gene by proximal promoter and novel intronic regulatory regions during erythroid differentiation. Molecular and Cellular Biology. 30: 2811-22. PMID 20368355 DOI: 10.1128/Mcb.01016-09  0.374
2009 Sengupta T, Cohet N, Morlé F, Bieker JJ. Distinct modes of gene regulation by a cell-specific transcriptional activator. Proceedings of the National Academy of Sciences of the United States of America. 106: 4213-8. PMID 19251649 DOI: 10.1073/Pnas.0808347106  0.385
2009 Migliaccio G, Dell’Aversana C, Nebbioso A, Alfani E, arricchio L, Mai A, Chaurasia P, Hoffman R, Bieker JJ, Altucci L, Migliaccio AR. Ontogenic-Specific Increasesin HDAC1 Activity and Transcription Factor Association During the Maturation of Human Adult Erythroblasts in Vitro. Blood. 114: 1978-1978. DOI: 10.1182/Blood.V114.22.1978.1978  0.377
2009 Bieker JJ. Expanded role for EKLF/KLF1 within the hematopoietic lineage The Biology of KrüPpel-Like Factors. 83-93. DOI: 10.1007/978-4-431-87775-2-6  0.352
2008 Sengupta T, Chen K, Milot E, Bieker JJ. Acetylation of EKLF is essential for epigenetic modification and transcriptional activation of the beta-globin locus. Molecular and Cellular Biology. 28: 6160-70. PMID 18710946 DOI: 10.1128/Mcb.00919-08  0.409
2008 Lohmann F, Bieker JJ. Activation of Eklf expression during hematopoiesis by Gata2 and Smad5 prior to erythroid commitment. Development (Cambridge, England). 135: 2071-82. PMID 18448565 DOI: 10.1242/Dev.018200  0.354
2008 Quadrini KJ, Gruzglin E, Bieker JJ. Non-random subcellular distribution of variant EKLF in erythroid cells. Experimental Cell Research. 314: 1595-604. PMID 18329016 DOI: 10.1016/J.Yexcr.2008.01.033  0.599
2007 Siatecka M, Xue L, Bieker JJ. Sumoylation of EKLF promotes transcriptional repression and is involved in inhibition of megakaryopoiesis. Molecular and Cellular Biology. 27: 8547-60. PMID 17938210 DOI: 10.1128/Mcb.00589-07  0.421
2007 Frontelo P, Manwani D, Galdass M, Karsunky H, Lohmann F, Gallagher PG, Bieker JJ. Novel role for EKLF in megakaryocyte lineage commitment. Blood. 110: 3871-80. PMID 17715392 DOI: 10.1182/Blood-2007-03-082065  0.368
2007 Manwani D, Galdass M, Bieker JJ. Altered regulation of beta-like globin genes by a redesigned erythroid transcription factor. Experimental Hematology. 35: 39-47. PMID 17198872 DOI: 10.1016/J.Exphem.2006.09.004  0.457
2007 Perrine SP, Mankidy R, Boosalis MS, Bieker JJ, Faller DV. EKLF Is Recruited to the γ-Globin Gene Promoter as a Co-Activator and Is Required for γ-Globin Gene Induction by Short-Chain Fatty Acids. Blood. 110: 1771-1771. DOI: 10.1182/Blood.V110.11.1771.1771  0.3
2007 Bieker JJ. Novel role for EKLF in megakaryocyte–erythroid differential lineage commitment Blood Cells, Molecules, and Diseases. 38: 125. DOI: 10.1182/Blood.V108.11.4205.4205  0.358
2007 Siatecka M, Bieker JJ. Sumoylation of EKLF promotes transcriptional repression and is involved in inhibition of megakaryocytic cell differentiation Blood Cells, Molecules, and Diseases. 38: 177-178. DOI: 10.1016/J.Bcmd.2006.10.129  0.323
2006 Quadrini KJ, Bieker JJ. EKLF/KLF1 is ubiquitinated in vivo and its stability is regulated by activation domain sequences through the 26S proteasome. Febs Letters. 580: 2285-93. PMID 16579989 DOI: 10.1016/J.Febslet.2006.03.039  0.598
2006 Frontelo MP, Manwani D, Galdass M, Karsunky H, Gallagher PG, Bieker JJ. Novel Role for EKLF in Megakaryocyte-Erythroid Differential Lineage Commitment. Blood. 108: 4205-4205. DOI: 10.1182/blood.V108.11.4205.4205  0.358
2005 Im H, Grass JA, Johnson KD, Kim SI, Boyer ME, Imbalzano AN, Bieker JJ, Bresnick EH. Chromatin domain activation via GATA-1 utilization of a small subset of dispersed GATA motifs within a broad chromosomal region. Proceedings of the National Academy of Sciences of the United States of America. 102: 17065-70. PMID 16286657 DOI: 10.1073/Pnas.0506164102  0.438
2005 Bieker JJ. Probing the onset and regulation of erythroid cell-specific gene expression. The Mount Sinai Journal of Medicine, New York. 72: 333-8. PMID 16184297  0.415
2004 Chen X, Bieker JJ. Stage-specific repression by the EKLF transcriptional activator. Molecular and Cellular Biology. 24: 10416-24. PMID 15542849 DOI: 10.1128/Mcb.24.23.10416-10424.2004  0.425
2004 Xue L, Chen X, Chang Y, Bieker JJ. Regulatory elements of the EKLF gene that direct erythroid cell-specific expression during mammalian development. Blood. 103: 4078-83. PMID 14764531 DOI: 10.1182/Blood-2003-09-3231  0.377
2002 Quadrini KJ, Bieker JJ. Krüppel-like zinc fingers bind to nuclear import proteins and are required for efficient nuclear localization of erythroid Krüppel-like factor. The Journal of Biological Chemistry. 277: 32243-52. PMID 12072445 DOI: 10.1074/Jbc.M205677200  0.603
2002 Adelman CA, Chattopadhyay S, Bieker JJ. The BMP/BMPR/Smad pathway directs expression of the erythroid-specific EKLF and GATA1 transcription factors during embryoid body differentiation in serum-free media. Development (Cambridge, England). 129: 539-49. PMID 11807044  0.316
2001 Chen X, Bieker JJ. Unanticipated repression function linked to erythroid Krüppel-like factor Molecular and Cellular Biology. 21: 3118-3125. PMID 11287616 DOI: 10.1128/Mcb.21.9.3118-3125.2001  0.462
2001 Zhang W, Kadam S, Emerson BM, Bieker JJ. Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex Molecular and Cellular Biology. 21: 2413-2422. PMID 11259590 DOI: 10.1128/Mcb.21.7.2413-2422.2001  0.439
1998 Armstrong JA, Bieker JJ, Emerson BM. A SWI/SNF-related chromatin remodeling complex, E-RC1, is required for tissue-specific transcriptional regulation by EKLF in vitro. Cell. 95: 93-104. PMID 9778250 DOI: 10.1016/S0092-8674(00)81785-7  0.404
1998 Chen X, Reitman M, Bieker JJ. Chromatin structure and transcriptional control elements of the erythroid Kruppel-like factor (EKLF) gene Journal of Biological Chemistry. 273: 25031-25040. PMID 9737959 DOI: 10.1074/Jbc.273.39.25031  0.398
1998 Spadaccini A, Tilbrook PA, Sarna MK, Crossley M, Bieker JJ, Klinken SP. Transcription factor erythroid Krüppel-like factor (EKLF) is essential for the erythropoietin-induced hemoglobin production but not for proliferation, viability, or morphological maturation. The Journal of Biological Chemistry. 273: 23793-8. PMID 9726989 DOI: 10.1074/Jbc.273.37.23793  0.391
1998 Ouyang L, Chen X, Bieker JJ. Regulation of erythroid Krüppel-like factor (EKLF) transcriptional activity by phosphorylation of a protein kinase casein kinase II site within its interaction domain. The Journal of Biological Chemistry. 273: 23019-25. PMID 9722526 DOI: 10.1074/Jbc.273.36.23019  0.353
1998 Zhang W, Bieker JJ. Acetylation and modulation of erythroid Krüppel-like factor (EKLF) activity by interaction with histone acetyltransferases Proceedings of the National Academy of Sciences of the United States of America. 95: 9855-9860. PMID 9707565 DOI: 10.1073/Pnas.95.17.9855  0.303
1998 Bieker JJ, Ouyang L, Chen X. Transcriptional factors for specific globin genes. Annals of the New York Academy of Sciences. 850: 64-9. PMID 9668528 DOI: 10.1111/J.1749-6632.1998.Tb10463.X  0.424
1998 Bieker JJ. Erythroid-specific transcription Current Opinion in Hematology. 5: 145-150. PMID 9570708 DOI: 10.1097/00062752-199803000-00010  0.399
1996 Bieker JJ. Isolation, genomic structure, and expression of human erythroid krüppel-like factor (EKLF) Dna and Cell Biology. 15: 347-352. PMID 8924208 DOI: 10.1089/Dna.1996.15.347  0.335
1996 Chen X, Bieker JJ. Erythroid Kruppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions Embo Journal. 15: 5888-5896. PMID 8918466  0.444
1996 Southwood CM, Downs KM, Bieker JJ. Erythroid Kruppel-like factor exhibits an early and sequentially localized pattern of expression during mammalian erythroid ontogeny Developmental Dynamics. 206: 248-259. PMID 8896981 DOI: 10.1002/(Sici)1097-0177(199607)206:3<248::Aid-Aja3>3.0.Co;2-I  0.42
1996 Gregory RC, Taxman DJ, Seshasayee D, Kensinger MH, Bieker JJ, Wojchowski DM. Functional interaction of GATA1 with erythroid Krüppel-like factor and SP1 at defined erythroid promoters Blood. 87: 1793-1801. PMID 8634425 DOI: 10.1182/Blood.V87.5.1793.Bloodjournal8751793  0.306
1996 Chen X, Bieker JJ. Erythroid Krüppel-like factor (EKLF) contains a multifunctional transcriptional activation domain important for inter- and intramolecular interactions. The Embo Journal. 15: 5888-5896. DOI: 10.1002/j.1460-2075.1996.tb00975.x  0.39
1995 Bieker JJ, Southwood CM. The erythroid Kruppel-like factor transactivation domain is a critical component for cell-specific inducibility of a β-globin promoter Molecular and Cellular Biology. 15: 852-860. PMID 7823951 DOI: 10.1128/Mcb.15.2.852  0.424
1994 Crossley M, Tsang AP, Bieker JJ, Orkin SH. Regulation of the erythroid Kruppel-like factor (EKLF) gene promoter by the erythroid transcription factor GATA-1 Journal of Biological Chemistry. 269: 15440-15444. PMID 8195185  0.388
1993 Miller IJ, Bieker JJ. A novel, erythroid cell-specific murine transcription factor that binds to the CACCC element and is related to the Kruppel family of nuclear proteins Molecular and Cellular Biology. 13: 2776-2786. PMID 7682653 DOI: 10.1128/Mcb.13.5.2776  0.481
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