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Balazs Sarkadi - Publications

Affiliations: 
Semmelweis Egyetem, Hungary 
Area:
Genetics, Medicine and Surgery, Cell Biology
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Year Citation  Score
2023 Mózner O, Zámbó B, Bartos Z, Gergely A, Szabó KS, Jezsó B, Telbisz Á, Várady G, Homolya L, Hegedűs T, Sarkadi B. Expression, Function and Trafficking of the Human ABCG2 Multidrug Transporter Containing Mutations in an Unstructured Cytoplasmic Loop. Membranes. 13. PMID 37887994 DOI: 10.3390/membranes13100822  0.415
2023 Bakos É, Temesszentandrási-Ambrus C, Özvegy-Laczka C, Gáborik Z, Sarkadi B, Telbisz Á. Interactions of the Anti-SARS-CoV-2 Agents Molnupiravir and Nirmatrelvir/Paxlovid with Human Drug Transporters. International Journal of Molecular Sciences. 24. PMID 37510996 DOI: 10.3390/ijms241411237  0.305
2022 Kulin A, Kucsma N, Bohár B, Literáti-Nagy B, Korányi L, Cserepes J, Somogyi A, Sarkadi B, Szabó E, Várady G. Genetic Modulation of the GLUT1 Transporter Expression-Potential Relevance in Complex Diseases. Biology. 11. PMID 36421383 DOI: 10.3390/biology11111669  0.8
2022 Szabó E, Kulin A, Jezsó B, Kucsma N, Sarkadi B, Várady G. Selective Fluorescent Probes for High-Throughput Functional Diagnostics of the Human Multidrug Transporter P-Glycoprotein (ABCB1). International Journal of Molecular Sciences. 23. PMID 36142507 DOI: 10.3390/ijms231810599  0.384
2022 Mioč M, Telbisz Á, Radman K, Bertoša B, Šumanovac T, Sarkadi B, Kralj M. Interaction of crown ethers with the ABCG2 transporter and their implication for multidrug resistance reversal. Histochemistry and Cell Biology. PMID 35648291 DOI: 10.1007/s00418-022-02106-z  0.361
2021 Szabó E, Kulin A, Mózner O, Korányi L, Literáti-Nagy B, Vitai M, Cserepes J, Sarkadi B, Várady G. Potential role of the ABCG2-Q141K polymorphism in type 2 diabetes. Plos One. 16: e0260957. PMID 34855903 DOI: 10.1371/journal.pone.0260957  0.786
2021 Ambrus C, Bakos É, Sarkadi B, Özvegy-Laczka C, Telbisz Á. Interactions of anti-COVID-19 drug candidates with hepatic transporters may cause liver toxicity and affect pharmacokinetics. Scientific Reports. 11: 17810. PMID 34497279 DOI: 10.1038/s41598-021-97160-3  0.331
2021 Mózner O, Zámbó B, Sarkadi B. Modulation of the Human Erythroid Plasma Membrane Calcium Pump (PMCA4b) Expression by Polymorphic Genetic Variants. Membranes. 11. PMID 34436349 DOI: 10.3390/membranes11080586  0.319
2021 Szabó E, Kulin A, Korányi L, Literáti-Nagy B, Cserepes J, Somogyi A, Sarkadi B, Várady G. Alterations in erythrocyte membrane transporter expression levels in type 2 diabetic patients. Scientific Reports. 11: 2765. PMID 33531564 DOI: 10.1038/s41598-021-82417-8  0.803
2020 Sarkadi B, Homolya L, Hegedűs T. The ABCG2/BCRP transporter and its variants - from structure to pathology. Febs Letters. PMID 33015850 DOI: 10.1002/1873-3468.13947  0.381
2020 Nagy T, Tóth Á, Telbisz Á, Sarkadi B, Tordai H, Tordai A, Hegedűs T. The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations. Cellular and Molecular Life Sciences : Cmls. PMID 32979053 DOI: 10.1007/s00018-020-03651-3  0.33
2020 Sarkadi B, Meszaros K, Krencz I, Canu L, Krokker L, Zakarias S, Barna G, Sebestyen A, Papay J, Hujber Z, Butz H, Darvasi O, Igaz P, Doczi J, Luconi M, et al. Glutaminases as a Novel Target for SDHB-Associated Pheochromocytomas/Paragangliomas. Cancers. 12. PMID 32150977 DOI: 10.3390/Cancers12030599  0.406
2020 Kovacsics D, Brózik A, Tihanyi B, Matula Z, Borsy A, Mészáros N, Szabó E, Németh E, Fóthi Á, Zámbó B, Szüts D, Várady G, Orbán TI, Apáti Á, Sarkadi B. Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells. Biochemical Pharmacology. 113865. PMID 32142727 DOI: 10.1016/J.Bcp.2020.113865  0.441
2020 Tóth S, Szepesi Á, Tran-Nguyen VK, Sarkadi B, Német K, Falson P, Di Pietro A, Szakács G, Boumendjel A. Synthesis and Anticancer Cytotoxicity of Azaaurones Overcoming Multidrug Resistance. Molecules (Basel, Switzerland). 25. PMID 32050702 DOI: 10.3390/Molecules25030764  0.367
2019 Mózner O, Bartos Z, Zámbó B, Homolya L, Hegedűs T, Sarkadi B. Cellular Processing of the ABCG2 Transporter-Potential Effects on Gout and Drug Metabolism. Cells. 8. PMID 31597297 DOI: 10.3390/Cells8101215  0.497
2019 Zámbó B, Mózner O, Bartos Z, Török G, Várady G, Telbisz Á, Homolya L, Orbán TI, Sarkadi B. Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter. Cellular and Molecular Life Sciences : Cmls. PMID 31254042 DOI: 10.1007/S00018-019-03186-2  0.507
2019 Kovacsics D, Mészáros N, Tihanyi B, Matula Z, Borsy A, Szabó E, Várady G, Orbán T, Apáti Á, Fóthi Á, Brózik A, Sarkadi B. Abstract 3027: Pharmacological regulation of the ABCG2 multidrug transporter in A549 non-small cell lung cancer cells Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3027  0.364
2018 Apáti Á, Varga N, Berecz T, Erdei Z, Homolya L, Sarkadi B. Application of human pluripotent stem cells and pluripotent stem cell-derived cellular models for assessing drug toxicity. Expert Opinion On Drug Metabolism & Toxicology. PMID 30526128 DOI: 10.1080/17425255.2019.1558207  0.346
2018 Temesszentandrási-Ambrus C, Tóth S, Verma R, Bánhegyi P, Szabadkai I, Baska F, Szántai-Kis C, Hartkoorn RC, Lingerfelt MA, Sarkadi B, Szakács G, Őrfi L, Nagaraja V, Ekins S, Telbisz Á. Characterization of new, efficient Mycobacterium tuberculosis topoisomerase-I inhibitors and their interaction with human ABC multidrug transporters. Plos One. 13: e0202749. PMID 30183750 DOI: 10.1371/Journal.Pone.0202749  0.393
2018 Zámbó B, Bartos Z, Mózner O, Szabó E, Várady G, Poór G, Pálinkás M, Andrikovics H, Hegedűs T, Homolya L, Sarkadi B. Clinically relevant mutations in the ABCG2 transporter uncovered by genetic analysis linked to erythrocyte membrane protein expression. Scientific Reports. 8: 7487. PMID 29749379 DOI: 10.1038/S41598-018-25695-Z  0.473
2018 Erdei Z, Schamberger A, Török G, Szebényi K, Várady G, Orbán TI, Homolya L, Sarkadi B, Apáti Á. Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells. Plos One. 13: e0194925. PMID 29649238 DOI: 10.1371/Journal.Pone.0194925  0.425
2018 Vőfély G, Berecz T, Szabó E, Szebényi K, Hathy E, Orbán TI, Sarkadi B, Homolya L, Marchetto MC, Réthelyi JM, Apáti Á. Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein. Molecular and Cellular Neurosciences. PMID 29425968 DOI: 10.1016/J.Mcn.2018.02.003  0.318
2018 Szabó E, Türk D, Telbisz Á, Kucsma N, Horváth T, Szakács G, Homolya L, Sarkadi B, Várady G. A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions. Plos One. 13: e0190629. PMID 29342177 DOI: 10.1371/Journal.Pone.0190629  0.434
2017 Tordai H, Jakab K, Gyimesi G, András K, Brózik A, Sarkadi B, Hegedus T. ABCMdb reloaded: updates on mutations in ATP binding cassette proteins. Database : the Journal of Biological Databases and Curation. 2017. PMID 28365738 DOI: 10.1093/Database/Bax023  0.341
2017 Zámbó B, Várady G, Padányi R, Szabó E, Németh A, Langó T, Enyedi Á, Sarkadi B. Decreased calcium pump expression in human erythrocytes is connected to a minor haplotype in the ATP2B4 gene. Cell Calcium. PMID 28216081 DOI: 10.1016/J.Ceca.2017.02.001  0.437
2016 László L, Sarkadi B, Hegedűs T. Jump into a New Fold-A Homology Based Model for the ABCG2/BCRP Multidrug Transporter. Plos One. 11: e0164426. PMID 27741279 DOI: 10.1371/Journal.Pone.0164426  0.48
2016 Nerada Z, Hegyi Z, Szepesi Á, Tóth S, Hegedüs C, Várady G, Matula Z, Homolya L, Sarkadi B, Telbisz Á. Application of fluorescent dye substrates for functional characterization of ABC multidrug transporters at a single cell level. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 27602881 DOI: 10.1002/Cyto.A.22931  0.482
2016 Sándor S, Jordanidisz T, Schamberger A, Várady G, Erdei Z, Apáti Á, Sarkadi B, Orbán TI. Functional characterization of the ABCG2 5' non-coding exon variants: Stem cell specificity, translation efficiency and the influence of drug selection. Biochimica Et Biophysica Acta. PMID 27191194 DOI: 10.1016/J.Bbagrm.2016.05.007  0.429
2016 Apáti Á, Berecz T, Sarkadi B. Calcium signaling in human pluripotent stem cells. Cell Calcium. 59: 117-23. PMID 26922096 DOI: 10.1016/J.Ceca.2016.01.005  0.346
2016 Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, ... ... Sarkadi B, et al. Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nature Communications. 7: 10286. PMID 26743714 DOI: 10.1038/Ncomms10286  0.332
2016 Apáti Á, Szebényi K, Erdei Z, Várady G, Orbán TI, Sarkadi B. The importance of drug transporters in human pluripotent stem cells and in early tissue differentiation. Expert Opinion On Drug Metabolism & Toxicology. 12: 77-92. PMID 26592535 DOI: 10.1517/17425255.2016.1121382  0.472
2015 Várady G, Szabó E, Fehér Á, Németh A, Zámbó B, Pákáski M, Janka Z, Sarkadi B. Alterations of membrane protein expression in red blood cells of Alzheimer's disease patients. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 334-8. PMID 27239515 DOI: 10.1016/J.Dadm.2015.06.007  0.389
2015 Szebényi K, Füredi A, Kolacsek O, Pergel E, Bősze Z, Bender B, Vajdovich P, Tóvári J, Homolya L, Szakács G, Héja L, Enyedi Á, Sarkadi B, Apáti Á, Orbán TI. Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling. Scientific Reports. 5: 12645. PMID 26234466 DOI: 10.1038/Srep12645  0.31
2015 Hegedűs T, Chaubey PM, Várady G, Szabó E, Sarankó H, Hofstetter L, Roschitzki B, Stieger B, Sarkadi B. Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications. Database : the Journal of Biological Databases and Curation. 2015: bav056. PMID 26078478 DOI: 10.1093/Database/Bav056  0.396
2015 Erdélyi-Belle B, Török G, Apáti Á, Sarkadi B, Schaff Z, Kiss A, Homolya L. Expression of Tight Junction Components in Hepatocyte-Like Cells Differentiated from Human Embryonic Stem Cells. Pathology Oncology Research : Por. 21: 1059-70. PMID 25845432 DOI: 10.1007/S12253-015-9936-5  0.391
2015 Bacskai I, Mázló A, Kis-Tóth K, Szabó A, Panyi G, Sarkadi B, Apáti Á, Rajnavölgyi É. Mesenchymal Stromal Cell-Like Cells Set the Balance of Stimulatory and Inhibitory Signals in Monocyte-Derived Dendritic Cells. Stem Cells and Development. 24: 1805-16. PMID 25808140 DOI: 10.1089/Scd.2014.0509  0.345
2015 Tóth A, Brózik A, Szakács G, Sarkadi B, Hegedüs T. A novel mathematical model describing adaptive cellular drug metabolism and toxicity in the chemoimmune system. Plos One. 10: e0115533. PMID 25699998 DOI: 10.1371/Journal.Pone.0115533  0.363
2015 Hegedüs C, Telbisz Á, Hegedűs T, Sarkadi B, Özvegy-Laczka C. Lipid regulation of the ABCB1 and ABCG2 multidrug transporters. Advances in Cancer Research. 125: 97-137. PMID 25640268 DOI: 10.1016/Bs.Acr.2014.10.004  0.424
2015 Gál Z, Hegedüs C, Szakács G, Váradi A, Sarkadi B, Özvegy-Laczka C. Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter. Biochimica Et Biophysica Acta. 1848: 477-87. PMID 25445676 DOI: 10.1016/J.Bbamem.2014.11.006  0.444
2015 Szepesi Á, Matula Z, Szigeti A, Várady G, Szabó G, Uher F, Sarkadi B, Német K. ABCG2 is a selectable marker for enhanced multilineage differentiation potential in periodontal ligament stem cells. Stem Cells and Development. 24: 244-52. PMID 25101689 DOI: 10.1089/Scd.2014.0177  0.431
2015 Szebényi K, Péntek A, Erdei Z, Várady G, Orbán TI, Sarkadi B, Apáti Á. Efficient generation of human embryonic stem cell-derived cardiac progenitors based on tissue-specific enhanced green fluorescence protein expression. Tissue Engineering. Part C, Methods. 21: 35-45. PMID 24734786 DOI: 10.1089/Ten.Tec.2013.0646  0.337
2015 Pálinkás M, Rásonyi R, Kiss C, Juhász P, Donáth J, Mikó I, Szekeres L, Tordai A, Andrikovics H, Szabó E, Várady G, Sarkadi B, Poór G. A2.36 Genetic variability and gout Annals of the Rheumatic Diseases. 74: A30.2-A31. DOI: 10.1136/Annrheumdis-2015-207259.71  0.383
2014 Koszarska M, Kucsma N, Kiss K, Varady G, Gera M, Antalffy G, Andrikovics H, Tordai A, Studzian M, Strapagiel D, Pulaski L, Tani Y, Sarkadi B, Szakacs G. Screening the expression of ABCB6 in erythrocytes reveals an unexpectedly high frequency of Lan mutations in healthy individuals. Plos One. 9: e111590. PMID 25360778 DOI: 10.1371/Journal.Pone.0111590  0.366
2014 Erdei Z, Lőrincz R, Szebényi K, Péntek A, Varga N, Likó I, Várady G, Szakács G, Orbán TI, Sarkadi B, Apáti A. Expression pattern of the human ABC transporters in pluripotent embryonic stem cells and in their derivatives. Cytometry. Part B, Clinical Cytometry. 86: 299-310. PMID 24729538 DOI: 10.1002/Cyto.B.21168  0.472
2014 Telbisz Á, Hegedüs C, Váradi A, Sarkadi B, Özvegy-Laczka C. Regulation of the function of the human ABCG2 multidrug transporter by cholesterol and bile acids: effects of mutations in potential substrate and steroid binding sites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 575-85. PMID 24384916 DOI: 10.1124/Dmd.113.055731  0.46
2013 Gauthier C, Ozvegy-Laczka C, Szakacs G, Sarkadi B, Di Pietro A. ABCG2 is not able to catalyze glutathione efflux and does not contribute to GSH-dependent collateral sensitivity. Frontiers in Pharmacology. 4: 138. PMID 24312054 DOI: 10.3389/Fphar.2013.00138  0.519
2013 Winter E, Lecerf-Schmidt F, Gozzi G, Peres B, Lightbody M, Gauthier C, Ozvegy-Laczka C, Szakacs G, Sarkadi B, Creczynski-Pasa TB, Boumendjel A, Di Pietro A. Structure-activity relationships of chromone derivatives toward the mechanism of interaction with and inhibition of breast cancer resistance protein ABCG2. Journal of Medicinal Chemistry. 56: 9849-60. PMID 24304387 DOI: 10.1021/Jm401649J  0.353
2013 Várady G, Cserepes J, Németh A, Szabó E, Sarkadi B. Cell surface membrane proteins as personalized biomarkers: where we stand and where we are headed. Biomarkers in Medicine. 7: 803-19. PMID 24044572 DOI: 10.2217/Bmm.13.90  0.789
2013 Sarankó H, Tordai H, Telbisz Á, Özvegy-Laczka C, Erdős G, Sarkadi B, Hegedűs T. Effects of the gout-causing Q141K polymorphism and a CFTR ΔF508 mimicking mutation on the processing and stability of the ABCG2 protein. Biochemical and Biophysical Research Communications. 437: 140-5. PMID 23800412 DOI: 10.1016/j.bbrc.2013.06.054  0.346
2013 Pomozi V, Le Saux O, Brampton C, Apana A, Iliás A, Szeri F, Martin L, Monostory K, Paku S, Sarkadi B, Szakács G, Váradi A. ABCC6 is a basolateral plasma membrane protein. Circulation Research. 112: e148-51. PMID 23625951 DOI: 10.1161/Circresaha.111.300194  0.364
2013 Apáti A, Pászty K, Hegedus L, Kolacsek O, Orbán TI, Erdei Z, Szebényi K, Péntek A, Enyedi A, Sarkadi B. Characterization of calcium signals in human embryonic stem cells and in their differentiated offspring by a stably integrated calcium indicator protein Cellular Signalling. 25: 752-759. PMID 23305950 DOI: 10.1016/J.Cellsig.2012.12.024  0.354
2013 Grabundzija I, Wang J, Sebe A, Erdei Z, Kajdi R, Devaraj A, Steinemann D, Szuhai K, Stein U, Cantz T, Schambach A, Baum C, Izsvák Z, Sarkadi B, Ivics Z. Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells. Nucleic Acids Research. 41: 1829-47. PMID 23275558 DOI: 10.1093/Nar/Gks1305  0.369
2013 Telbisz Á, Özvegy-Laczka C, Hegedűs T, Váradi A, Sarkadi B. Effects of the lipid environment, cholesterol and bile acids on the function of the purified and reconstituted human ABCG2 protein. The Biochemical Journal. 450: 387-95. PMID 23205634 DOI: 10.1042/Bj20121485  0.463
2013 Erdei Z, Sarkadi B, Brózik A, Szebényi K, Várady G, Makó V, Péntek A, Orbán TI, Apáti Á. Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response. European Biophysics Journal : Ebj. 42: 169-79. PMID 22851001 DOI: 10.1007/S00249-012-0838-0  0.457
2012 Kasza I, Várady G, Andrikovics H, Koszarska M, Tordai A, Scheffer GL, Németh A, Szakács G, Sarkadi B. Expression levels of the ABCG2 multidrug transporter in human erythrocytes correspond to pharmacologically relevant genetic variations. Plos One. 7: e48423. PMID 23166586 DOI: 10.1371/Journal.Pone.0048423  0.794
2012 de Boussac H, Orbán TI, Várady G, Tihanyi B, Bacquet C, Brózik A, Váradi A, Sarkadi B, Arányi T. Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters. Biochemical and Biophysical Research Communications. 426: 172-6. PMID 22922104 DOI: 10.1016/J.Bbrc.2012.08.046  0.39
2012 Gyimesi G, Borsodi D, Sarankó H, Tordai H, Sarkadi B, Hegedűs T. ABCMdb: a database for the comparative analysis of protein mutations in ABC transporters, and a potential framework for a general application. Human Mutation. 33: 1547-56. PMID 22693078 DOI: 10.1002/Humu.22138  0.327
2012 Hegedüs C, Truta-Feles K, Antalffy G, Várady G, Német K, Ozvegy-Laczka C, Kéri G, Orfi L, Szakács G, Settleman J, Váradi A, Sarkadi B. Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance. Biochemical Pharmacology. 84: 260-7. PMID 22548830 DOI: 10.1016/J.Bcp.2012.04.010  0.419
2012 Hegedüs C, Truta-Feles K, Antalffy G, Brózik A, Kasza I, Német K, Orbán TI, Özvegy-Laczka C, Váradi A, Sarkadi B. PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter. Biochemical and Biophysical Research Communications. 420: 869-74. PMID 22449574 DOI: 10.1016/J.Bbrc.2012.03.090  0.772
2012 Telbisz Á, Hegedüs C, Özvegy-Laczka C, Goda K, Várady G, Takáts Z, Szabó E, Sorrentino BP, Váradi A, Sarkadi B. Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 45: 101-9. PMID 22115866 DOI: 10.1016/J.Ejps.2011.10.021  0.485
2012 Apáti Á, Pászty K, Erdei Z, Szebényi K, Homolya L, Sarkadi B. Calcium signaling in pluripotent stem cells. Molecular and Cellular Endocrinology. 353: 57-67. PMID 21945604 DOI: 10.1016/J.Mce.2011.08.038  0.314
2012 Sarkadi B, Schatten G. Stem cell course in the Middle East: science diplomacy and international collaborations during the Arab spring. Stem Cell Reviews. 8: 87-90. PMID 21647552 DOI: 10.1007/S12015-011-9277-Z  0.306
2012 Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedűs T. Corrigendum to “ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions” [Biochim. Biophys. Acta 1808 (2011) 2954–2964] Biochimica Et Biophysica Acta (Bba) - Biomembranes. 1818: 1435. DOI: 10.1016/J.Bbamem.2012.01.004  0.384
2011 Szebényi K, Erdei Z, Péntek A, Sebe A, Orbán TI, Sarkadi B, Apáti Á. Human pluripotent stem cells in pharmacological and toxicological screening: new perspectives for personalized medicine. Personalized Medicine. 8: 347-364. PMID 29783530 DOI: 10.2217/Pme.11.19  0.338
2011 Fülöp K, Jiang Q, Wetering KV, Pomozi V, Szabó PT, Arányi T, Sarkadi B, Borst P, Uitto J, Váradi A. ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum. Biochemical and Biophysical Research Communications. 415: 468-71. PMID 22056557 DOI: 10.1016/J.Bbrc.2011.10.095  0.346
2011 Varga N, Veréb Z, Rajnavölgyi E, Német K, Uher F, Sarkadi B, Apáti A. Mesenchymal stem cell like (MSCl) cells generated from human embryonic stem cells support pluripotent cell growth. Biochemical and Biophysical Research Communications. 414: 474-80. PMID 21971558 DOI: 10.1016/J.Bbrc.2011.09.089  0.328
2011 Gyimesi G, Ramachandran S, Kota P, Dokholyan NV, Sarkadi B, Hegedus T. ATP hydrolysis at one of the two sites in ABC transporters initiates transport related conformational transitions. Biochimica Et Biophysica Acta. 1808: 2954-64. PMID 21840296 DOI: 10.1016/J.Bbamem.2011.07.038  0.387
2011 Procházková J, Kubala L, Kotasová H, Gudernová I, Šrámková Z, Pekarová M, Sarkadi B, Pacherník J. ABC transporters affect the detection of intracellular oxidants by fluorescent probes. Free Radical Research. 45: 779-87. PMID 21568630 DOI: 10.3109/10715762.2011.579120  0.411
2011 Brózik A, Hegedüs C, Erdei Z, Hegedus T, Özvegy-Laczka C, Szakács G, Sarkadi B. Tyrosine kinase inhibitors as modulators of ATP binding cassette multidrug transporters: substrates, chemosensitizers or inducers of acquired multidrug resistance? Expert Opinion On Drug Metabolism & Toxicology. 7: 623-42. PMID 21410427 DOI: 10.1517/17425255.2011.562892  0.408
2011 Homolya L, Orbán TI, Csanády L, Sarkadi B. Mitoxantrone is expelled by the ABCG2 multidrug transporter directly from the plasma membrane. Biochimica Et Biophysica Acta. 1808: 154-63. PMID 20691148 DOI: 10.1016/J.Bbamem.2010.07.031  0.472
2010 Sarkadi B, Szakács G. Understanding transport through pharmacological barriers--are we there yet? Nature Reviews. Drug Discovery. 9: 897-8. PMID 21031004 DOI: 10.1038/Nrd3187-C1  0.386
2010 Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gagliardi M, McElligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, et al. The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance. The Journal of Pharmacology and Experimental Therapeutics. 335: 302-13. PMID 20699436 DOI: 10.1124/Jpet.110.170415  0.301
2010 Nathwani SM, Butler S, Fayne D, McGovern NN, Sarkadi B, Meegan MJ, Lloyd DG, Campiani G, Lawler M, Williams DC, Zisterer DM. Novel microtubule-targeting agents, pyrrolo-1,5-benzoxazepines, induce apoptosis in multi-drug-resistant cancer cells. Cancer Chemotherapy and Pharmacology. 66: 585-96. PMID 20020128 DOI: 10.1007/S00280-009-1200-9  0.429
2010 Sarkadi B, Orbán TI, Szakács G, Várady G, Schamberger A, Erdei Z, Szebényi K, Homolya L, Apáti A. Evaluation of ABCG2 expression in human embryonic stem cells: crossing the same river twice? Stem Cells (Dayton, Ohio). 28: 174-6. PMID 19924769 DOI: 10.1002/Stem.262  0.502
2009 Kasza I, Hegyi Z, Szabó K, Andrikovics H, Német K, Váradi A, Sarkadi B, Homolya L. Model system for the analysis of cell surface expression of human ABCA1. Bmc Cell Biology. 10: 93. PMID 20025763 DOI: 10.1186/1471-2121-10-93  0.775
2009 Hegedűs C, Özvegy‐Laczka C, Apáti Á, Magócsi M, Német K, Őrfi L, Kéri G, Katona M, Takáts Z, Váradi A, Szakács G, Sarkadi B. Interaction of nilotinib, dasatinib and bosutinib with ABCB1 and ABCG2: implications for altered anti-cancer effects and pharmacological properties British Journal of Pharmacology. 158: 1153-1164. PMID 19785662 DOI: 10.1111/J.1476-5381.2009.00383.X  0.399
2009 Katona M, Kiss K, Angyal V, Kucsma N, Sarkadi B, Takáts Z, Szakács G. A mass spectrometry based functional assay for the quantitative assessment of ABC transporter activity. Rapid Communications in Mass Spectrometry : Rcm. 23: 3372-6. PMID 19780062 DOI: 10.1002/Rcm.4259  0.416
2009 Hou YX, Li CZ, Palaniyandi K, Magtibay PM, Homolya L, Sarkadi B, Chang XB. Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport. Biochemistry. 48: 9122-31. PMID 19691360 DOI: 10.1021/Bi900675V  0.496
2009 Hegedus C, Ozvegy-Laczka C, Szakács G, Sarkadi B. Interaction of ABC multidrug transporters with anticancer protein kinase inhibitors: substrates and/or inhibitors? Current Cancer Drug Targets. 9: 252-72. PMID 19442047 DOI: 10.2174/156800909788166565  0.454
2009 Orbán TI, Apáti A, Németh A, Varga N, Krizsik V, Schamberger A, Szebényi K, Erdei Z, Várady G, Karászi E, Homolya L, Német K, Gócza E, Miskey C, Mátés L, ... ... Sarkadi B, et al. Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery. Stem Cells (Dayton, Ohio). 27: 1077-87. PMID 19415778 DOI: 10.1002/Stem.45  0.372
2009 Polgar O, Ediriwickrema LS, Robey RW, Sharma A, Hegde RS, Li Y, Xia D, Ward Y, Dean M, Ozvegy-Laczka C, Sarkadi B, Bates SE. Arginine 383 is a crucial residue in ABCG2 biogenesis. Biochimica Et Biophysica Acta. 1788: 1434-43. PMID 19406100 DOI: 10.1016/J.Bbamem.2009.04.016  0.401
2009 Hegedus C, Szakács G, Homolya L, Orbán TI, Telbisz A, Jani M, Sarkadi B. Ins and outs of the ABCG2 multidrug transporter: an update on in vitro functional assays. Advanced Drug Delivery Reviews. 61: 47-56. PMID 19135105 DOI: 10.1016/J.Addr.2008.09.007  0.451
2008 Apáti A, Orbán TI, Varga N, Németh A, Schamberger A, Krizsik V, Erdélyi-Belle B, Homolya L, Várady G, Padányi R, Karászi E, Kemna EW, Német K, Sarkadi B. High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells. Biochimica Et Biophysica Acta. 1778: 2700-9. PMID 18793608 DOI: 10.1016/J.Bbamem.2008.08.010  0.496
2008 Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B. Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter. The Journal of Biological Chemistry. 283: 26059-70. PMID 18644784 DOI: 10.1074/Jbc.M803230200  0.791
2008 Seres L, Cserepes J, Elkind NB, Törocsik D, Nagy L, Sarkadi B, Homolya L. Functional ABCG1 expression induces apoptosis in macrophages and other cell types. Biochimica Et Biophysica Acta. 1778: 2378-87. PMID 18619413 DOI: 10.1016/J.Bbamem.2008.06.010  0.797
2008 Orbán TI, Seres L, Ozvegy-Laczka C, Elkind NB, Sarkadi B, Homolya L. Combined localization and real-time functional studies using a GFP-tagged ABCG2 multidrug transporter. Biochemical and Biophysical Research Communications. 367: 667-73. PMID 18182157 DOI: 10.1016/J.Bbrc.2007.12.172  0.494
2007 Fuller MD, Thompson CH, Zhang ZR, Freeman CS, Schay E, Szakács G, Bakos E, Sarkadi B, McMaster D, French RJ, Pohl J, Kubanek J, McCarty NA. State-dependent inhibition of cystic fibrosis transmembrane conductance regulator chloride channels by a novel peptide toxin. The Journal of Biological Chemistry. 282: 37545-55. PMID 17951250 DOI: 10.1074/Jbc.M708079200  0.328
2007 Schwab R, Micsik T, Szokolóczi O, Schafer E, Tihanyi B, Tihanyi T, Kupcsulik P, Diófalvi K, Mersich T, Besznyak I, Zarand A, Mihalik R, Sarkadi B, Kéri G, Pap A, et al. Functional evaluation of multidrug resistance transporter activity in surgical samples of solid tumors. Assay and Drug Development Technologies. 5: 541-50. PMID 17767422 DOI: 10.1089/Adt.2007.067  0.444
2007 Telbisz A, Müller M, Ozvegy-Laczka C, Homolya L, Szente L, Váradi A, Sarkadi B. Membrane cholesterol selectively modulates the activity of the human ABCG2 multidrug transporter. Biochimica Et Biophysica Acta. 1768: 2698-713. PMID 17662239 DOI: 10.1016/J.Bbamem.2007.06.026  0.488
2006 Müller M, Klein I, Kopácsi S, Remaley AT, Rajnavölgyi E, Sarkadi B, Váradi A. Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity. Febs Letters. 580: 6139-44. PMID 17055487 DOI: 10.1016/J.Febslet.2006.10.012  0.492
2006 Sarkadi B, Homolya L, Szakács G, Váradi A. Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiological Reviews. 86: 1179-236. PMID 17015488 DOI: 10.1152/physrev.00037.2005  0.395
2006 Szatmari I, Vámosi G, Brazda P, Balint BL, Benko S, Széles L, Jeney V, Ozvegy-Laczka C, Szántó A, Barta E, Balla J, Sarkadi B, Nagy L. Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. The Journal of Biological Chemistry. 281: 23812-23. PMID 16785230 DOI: 10.1074/Jbc.M604890200  0.473
2006 Polgar O, Ozvegy-Laczka C, Robey RW, Morisaki K, Okada M, Tamaki A, Koblos G, Elkind NB, Ward Y, Dean M, Sarkadi B, Bates SE. Mutational studies of G553 in TM5 of ABCG2: a residue potentially involved in dimerization. Biochemistry. 45: 5251-60. PMID 16618113 DOI: 10.1021/Bi0521590  0.477
2006 Cervenak J, Andrikovics H, Ozvegy-Laczka C, Tordai A, Német K, Váradi A, Sarkadi B. The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology. Cancer Letters. 234: 62-72. PMID 16337740 DOI: 10.1016/J.Canlet.2005.01.061  0.52
2006 Tusnády GE, Sarkadi B, Simon I, Váradi A. Membrane topology of human ABC proteins. Febs Letters. 580: 1017-22. PMID 16337630 DOI: 10.1016/J.Febslet.2005.11.040  0.372
2005 Ozvegy-Laczka C, Cserepes J, Elkind NB, Sarkadi B. Tyrosine kinase inhibitor resistance in cancer: role of ABC multidrug transporters. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 8: 15-26. PMID 15939339 DOI: 10.1016/J.Drup.2005.02.002  0.81
2005 Morisaki K, Robey RW, Ozvegy-Laczka C, Honjo Y, Polgar O, Steadman K, Sarkadi B, Bates SE. Single nucleotide polymorphisms modify the transporter activity of ABCG2. Cancer Chemotherapy and Pharmacology. 56: 161-72. PMID 15838659 DOI: 10.1007/S00280-004-0931-X  0.455
2005 Elkind NB, Szentpétery Z, Apáti A, Ozvegy-Laczka C, Várady G, Ujhelly O, Szabó K, Homolya L, Váradi A, Buday L, Kéri G, Német K, Sarkadi B. Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib). Cancer Research. 65: 1770-7. PMID 15753373 DOI: 10.1158/0008-5472.Can-04-3303  0.764
2005 Ozvegy-Laczka C, Köblös G, Sarkadi B, Váradi A. Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Biochimica Et Biophysica Acta. 1668: 53-63. PMID 15670731 DOI: 10.1016/J.Bbamem.2004.11.005  0.525
2005 Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of Biological Chemistry. 280: 4219-27. PMID 15557326 DOI: 10.1074/Jbc.M411338200  0.785
2005 Ujhelly O, Kucsma N, Cervenak J, Chen L, Grez M, Sarkadi B, Nemet K. 1045. Overexpression of an ABCG2 Multidrug Transporter Variant Does Not Effect Proliferation or Differentiation of Hematopoetic Stem Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.592  0.78
2004 Glavinas H, Krajcsi P, Cserepes J, Sarkadi B. The role of ABC transporters in drug resistance, metabolism and toxicity. Current Drug Delivery. 1: 27-42. PMID 16305368  0.813
2004 Szentpétery Z, Kern A, Liliom K, Sarkadi B, Váradi A, Bakos E. The role of the conserved glycines of ATP-binding cassette signature motifs of MRP1 in the communication between the substrate-binding site and the catalytic centers. The Journal of Biological Chemistry. 279: 41670-8. PMID 15252017 DOI: 10.1074/Jbc.M406484200  0.424
2004 Cserepes J, Szentpétery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H, Klein I, Homolya L, Váradi A, Sarkadi B, Elkind NB. Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization. Biochemical and Biophysical Research Communications. 320: 860-7. PMID 15240127 DOI: 10.1016/J.Bbrc.2004.06.037  0.811
2004 Sarkadi B, Ozvegy-Laczka C, Német K, Váradi A. ABCG2 -- a transporter for all seasons. Febs Letters. 567: 116-20. PMID 15165903 DOI: 10.1016/j.febslet.2004.03.123  0.422
2004 Ozvegy-Laczka C, Hegedus T, Várady G, Ujhelly O, Schuetz JD, Váradi A, Kéri G, Orfi L, Német K, Sarkadi B. High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter. Molecular Pharmacology. 65: 1485-95. PMID 15155841 DOI: 10.1124/Mol.65.6.1485  0.801
2004 Kern A, Szentpétery Z, Liliom K, Bakos E, Sarkadi B, Váradi A. Nucleotides and transported substrates modulate different steps of the ATPase catalytic cycle of MRP1 multidrug transporter. The Biochemical Journal. 380: 549-60. PMID 14759224 DOI: 10.1042/Bj20031607  0.428
2004 Chu XY, Huskey SE, Braun MP, Sarkadi B, Evans DC, Evers R. Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3. The Journal of Pharmacology and Experimental Therapeutics. 309: 156-64. PMID 14722317 DOI: 10.1124/jpet.103.062091  0.324
2004 Ujhelly O, Cervenak J, Ozvegy CL, Grez M, Sarkadi B, Nemet K. 908. Selective enrichment of transduced cells for gene therapy of an inherited immune deficiency, chronic granulomatous disease Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.814  0.766
2003 Sinkó E, Iliás A, Ujhelly O, Homolya L, Scheffer GL, Bergen AA, Sarkadi B, Váradi A. Subcellular localization and N-glycosylation of human ABCC6, expressed in MDCKII cells. Biochemical and Biophysical Research Communications. 308: 263-9. PMID 12901863 DOI: 10.1016/S0006-291X(03)01349-4  0.788
2003 Homolya L, Váradi A, Sarkadi B. Multidrug resistance-associated proteins: Export pumps for conjugates with glutathione, glucuronate or sulfate. Biofactors (Oxford, England). 17: 103-14. PMID 12897433 DOI: 10.1002/Biof.5520170111  0.489
2003 Bodo A, Bakos E, Szeri F, Varadi A, Sarkadi B. Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions. The Journal of Biological Chemistry. 278: 23529-37. PMID 12704183 DOI: 10.1074/Jbc.M303515200  0.471
2003 Bodó A, Bakos E, Szeri F, Váradi A, Sarkadi B. The role of multidrug transporters in drug availability, metabolism and toxicity. Toxicology Letters. 140: 133-43. PMID 12676459  0.397
2003 Ujhelly O, Ozvegy C, Várady G, Cervenak J, Homolya L, Grez M, Scheffer G, Roos D, Bates SE, Váradi A, Sarkadi B, Német K. Application of a human multidrug transporter (ABCG2) variant as selectable marker in gene transfer to progenitor cells. Human Gene Therapy. 14: 403-12. PMID 12659681 DOI: 10.1089/104303403321209005  0.796
2003 Hegedüs T, Sessler T, Scott R, Thelin W, Bakos E, Váradi A, Szabó K, Homolya L, Milgram SL, Sarkadi B. C-terminal phosphorylation of MRP2 modulates its interaction with PDZ proteins. Biochemical and Biophysical Research Communications. 302: 454-61. PMID 12615054 DOI: 10.1016/S0006-291X(03)00196-7  0.371
2002 Ozvegy C, Váradi A, Sarkadi B. Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation. The Journal of Biological Chemistry. 277: 47980-90. PMID 12374800 DOI: 10.1074/Jbc.M207857200  0.528
2002 Hegedus T, Orfi L, Seprodi A, Váradi A, Sarkadi B, Kéri G. Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1. Biochimica Et Biophysica Acta. 1587: 318-25. PMID 12084474 DOI: 10.1016/S0925-4439(02)00095-9  0.511
2002 Váradi A, Szakács G, Bakos E, Sarkadi B. P glycoprotein and the mechanism of multidrug resistance. Novartis Foundation Symposium. 243: 54-65; discussion 65. PMID 11990782 DOI: 10.1002/0470846356.Ch5  0.405
2002 Iliás A, Urbán Z, Seidl TL, Le Saux O, Sinkó E, Boyd CD, Sarkadi B, Váradi A. Loss of ATP-dependent transport activity in pseudoxanthoma elasticum-associated mutants of human ABCC6 (MRP6). The Journal of Biological Chemistry. 277: 16860-7. PMID 11880368 DOI: 10.1074/Jbc.M110918200  0.49
2001 Szakács G, Langmann T, Özvegy C, Orsó E, Schmitz G, Váradi A, Sarkadi B. Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter. Biochemical and Biophysical Research Communications. 288: 1258-1264. PMID 11700048 DOI: 10.1006/Bbrc.2001.5905  0.47
2001 Szakács G, Özvegy C, Bakos É, Sarkadi B, Váradi A. Role of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysis. Biochemical Journal. 356: 71-75. PMID 11336637 DOI: 10.1042/0264-6021:3560071  0.455
2000 Szakács G, Özvegy C, Bakos É, Sarkadi B, Váradi A. Transition-state formation in ATPase-negative mutants of human MDR1 protein. Biochemical and Biophysical Research Communications. 276: 1314-1319. PMID 11027628 DOI: 10.1006/Bbrc.2000.3576  0.311
2000 Kern A, Felföldi F, Sarkadi B, Váradi A. Expression and Characterization of the N- and C-Terminal ATP-Binding Domains of MRP1☆ Biochemical and Biophysical Research Communications. 273: 913-919. PMID 10891347 DOI: 10.1006/Bbrc.2000.3040  0.35
1999 Sharom FJ, Yu X, Lu P, Liu R, Chu JW, Szabó K, Müller M, Hose CD, Monks A, Váradi A, Seprôdi J, Sarkadi B. Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems, and intact cells. Biochemical Pharmacology. 58: 571-86. PMID 10413294 DOI: 10.1016/S0006-2952(99)00139-2  0.458
1999 Szabó K, Szakács G, Hegedűs T, Sarkadi B. Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains. Journal of Biological Chemistry. 274: 12209-12212. PMID 10212185 DOI: 10.1074/Jbc.274.18.12209  0.401
1998 Váradi A, Tusnády GE, Bakos É, Sarkadi B. Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs Cytotechnology. 27: 71-79. PMID 19002784 DOI: 10.1023/A:1008031914247  0.42
1998 SzakÁCs G, Jakab K, Antal F, Sarkadi B. Diagnostics of multidrug resistance in cancer. Pathology & Oncology Research. 4: 251-257. PMID 9887354 DOI: 10.1007/Bf02905214  0.356
1997 Sarkadi B, Müller M. Search for specific inhibitors of multidrug resistance in cancer. Seminars in Cancer Biology. 8: 171-182. PMID 9465371 DOI: 10.1006/Scbi.1997.0069  0.403
1997 Szabó K, Bakos E, Welker E, Müller M, Goodfellow HR, Higgins CF, Váradi A, Sarkadi B. Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity. The Journal of Biological Chemistry. 272: 23165-71. PMID 9287320 DOI: 10.1074/Jbc.272.37.23165  0.408
1997 Bakos E, Klein I, Welker E, Szabó K, Müller M, Sarkadi B, Váradi A. Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region. The Biochemical Journal. 323: 777-83. PMID 9169612 DOI: 10.1042/Bj3230777  0.468
1996 Sarkadi B, Müller M, Holló Z. The multidrug transporters - Proteins of an ancient immune system Immunology Letters. 54: 215-219. PMID 9052881 DOI: 10.1016/S0165-2478(96)02676-4  0.477
1996 Bakos E, Hegedüs T, Holló Z, Welker E, Tusnády GE, Zaman GJ, Flens MJ, Váradi A, Sarkadi B. Membrane topology and glycosylation of the human multidrug resistance-associated protein. The Journal of Biological Chemistry. 271: 12322-6. PMID 8647833 DOI: 10.1074/Jbc.271.21.12322  0.477
1996 Holló Z, Homolya L, Hegedüs T, Sarkadi B. Transport properties of the multidrug resistance‐associated protein (MRP) in human tumour cells Febs Letters. 383: 99-104. PMID 8612802 DOI: 10.1016/0014-5793(96)00237-2  0.466
1996 Müller M, Bakos E, Welker E, Váradi A, Germann UA, Gottesman MM, Morse BS, Roninson IB, Sarkadi B. Altered drug-stimulated ATPase activity in mutants of the human multidrug resistance protein. The Journal of Biological Chemistry. 271: 1877-83. PMID 8567633 DOI: 10.1074/Jbc.271.4.1877  0.459
1994 Sarkadi B, Müller M, Homolya L, Holló Z, Seprödi J, Germann UA, Gottesman MM, Price EM, Boucher RC. Interaction of bioactive hydrophobic peptides with the human multidrug transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 8: 766-70. PMID 7914178 DOI: 10.1096/Fasebj.8.10.7914178  0.437
1992 Papp B, Enyedi A, Pászty K, Kovács T, Sarkadi B, Gárdos G, Magnier C, Wuytack F, Enouf J. Simultaneous presence of two distinct endoplasmic-reticulum-type calcium-pump isoforms in human cells. Characterization by radio-immunoblotting and inhibition by 2,5-di-(t-butyl)-1,4-benzohydroquinone. Biochemical Journal. 288: 297-302. PMID 1332697 DOI: 10.1042/Bj2880297  0.334
1990 Sarkadi B, Tordai A, Gárdos G. Membrane depolarization selectively inhibits receptor-operated calcium channels in human T (Jurkat) lymphoblasts. Biochimica Et Biophysica Acta. 1027: 130-140. PMID 2168754 DOI: 10.1016/0005-2736(90)90076-Z  0.307
1990 Sarkadi B, Tordai A, Müller M, Gárdos G. Regulation of stimulus-induced calcium transport pathways in human T (Jurkat) lymphoblasts Molecular Immunology. 27: 1297-1306. PMID 1703278 DOI: 10.1016/0161-5890(90)90034-W  0.301
1988 Sarkadi B, Enyedi A, Penniston JT, Verma AK, Dux L, Molnár E, Gárdos G. Characterization of membrane calcium pumps by simultaneous immunoblotting and 32P radiography. Biochimica Et Biophysica Acta. 939: 40-6. PMID 2964872 DOI: 10.1016/0005-2736(88)90044-2  0.317
1987 Sarkadi B, Enyedi Á, Gárdos G. Conformational changes of the in situ red cell membrane calcium pump affect its proteolysis Biochimica Et Biophysica Acta. 899: 129-133. PMID 2952170 DOI: 10.1016/0005-2736(87)90247-1  0.306
1984 Sarkadi B, Attisano L, Grinstein S, Buchwald M, Rothstein A. Volume regulation of Chinese hamster ovary cells in anisoosmotic media. Biochimica Et Biophysica Acta. 774: 159-68. PMID 6743652 DOI: 10.1016/0005-2736(84)90287-6  0.421
1984 Farkas G, Enyedi A, Sarkadi B, Gárdos G, Nagy Z, Faragó A. Cyclic AMP-dependent protein kinase stimulates the phosphorylation of phosphatidylinositol to phosphatidylinositol-4-monophosphate in a plasma membrane preparation from pig granulocytes. Biochemical and Biophysical Research Communications. 124: 871-6. PMID 6095827 DOI: 10.1016/0006-291X(84)91038-6  0.343
1984 Enyedi A, Faragó A, Sarkadi B, Gárdos G. Cyclic AMP-dependent protein kinase and Ca2+-calmodulin stimulate the formation of polyphosphoinositides in a sarcoplasmic reticulum preparation of rabbit heart. Febs Letters. 176: 235-8. PMID 6092135 DOI: 10.1016/0014-5793(84)80948-5  0.337
1983 Enyedi A, Faragó A, Sarkadi B, Szász I, Gárdos G. Cyclic AMP-dependent protein kinase stimulates the formation of polyphosphoinositides in the plasma membranes of different blood cells. Febs Letters. 161: 158-62. PMID 6309575 DOI: 10.1016/0014-5793(83)80751-0  0.393
1983 Sarkadi B, Enyedi A, Faragó A, Mészáros G, Kremmer T, Gárdos G. Cyclic AMP-dependent protein kinase stimulates the formation of polyphosphoinositides in lymphocyte plasma membrane. Febs Letters. 152: 195-8. PMID 6297997 DOI: 10.1016/0014-5793(83)80378-0  0.348
1982 Enyedi Á, Sarkadi B, Gárdos G. On the substrate specificity of the red cell calcium pump Biochimica Et Biophysica Acta. 687: 109-112. PMID 6978736 DOI: 10.1016/0005-2736(82)90177-8  0.365
1982 Enyedi Á, Sarkadi B, Nyers Á, Gárdos G. Effects of divalent metal ions on the calcium pump and membrane phosphorylation in human red cells Biochimica Et Biophysica Acta. 690: 41-49. PMID 6812632 DOI: 10.1016/0005-2736(82)90236-X  0.384
1982 Sarkadi B, Enyedi Á, Szász I, Gárdos G. Active calcium transport and calcium-dependent membrane phosphorylation in human peripheral blood lymphocytes. Cell Calcium. 3: 163-182. PMID 6288251 DOI: 10.1016/0143-4160(82)90012-4  0.32
1982 Sarkadi B, Enyedi Á, Nyers Á, Gárdos G. The function and regulation of the calcium pump in the erythrocyte membrane. Annals of the New York Academy of Sciences. 402: 329-348. PMID 6220640 DOI: 10.1111/J.1749-6632.1982.Tb25753.X  0.316
1981 Sarkadi B, Enyedi Á, Gárdos G. Metal-ATP complexes as substrates and free metal ions as activators of the red cell calcium pump Cell Calcium. 2: 449-458. DOI: 10.1016/0143-4160(81)90004-X  0.322
1980 Sarkadi B, Szász I, Gárdos G. Characteristics and regulation of active calcium transport in inside-out red cell membrane vesicles. Biochimica Et Biophysica Acta. 598: 326-338. PMID 6769484 DOI: 10.1016/0005-2736(80)90010-3  0.407
1980 Enyedi Á, Sarkadi B, Szász I, Bot G, Gárdos G. Molecular properties of the red cell calcium pump: II. Effects of calmodulin, proteolytic digestion and drugs on the calcium-induced membrane phosphorylation by ATP in inside-out red cell membrane vesicles Cell Calcium. 1: 299-310. DOI: 10.1016/0143-4160(80)90032-9  0.372
1980 Sarkadi B, Enyedi A, Gárdos G. Molecular properties of the red cell calcium pump: I. Effects of calmodulin, proteolytic digestion and drugs on the kinetics of active calcium uptake in inside-out red cell membrane vesicles Cell Calcium. 1: 287-297. DOI: 10.1016/0143-4160(80)90031-7  0.357
1978 Szász I, Hasitz M, Sarkadi B, Gárdos G. Phosphorylation of the Ca2+ pump intermediate in intact red cells, isolated membranes and inside-out vesicles. Molecular and Cellular Biochemistry. 22: 147-152. PMID 745597 DOI: 10.1007/Bf00496240  0.347
1978 Szász I, Sarkadi B, Schubert A, Gárdos G. Effects of lanthanum on calcium-dependent phenomena in human red cells. Biochimica Et Biophysica Acta. 512: 331-340. PMID 152127 DOI: 10.1016/0005-2736(78)90257-2  0.34
1977 Szász I, Sarkadi B, Gárdos G. Mechanism of Ca2+-dependent selective rapid K+-transport induced by propranolol in red cells. The Journal of Membrane Biology. 35: 75-93. PMID 886606 DOI: 10.1007/Bf01869941  0.322
1977 Sarkadi B, Szász I, Gerlóczy A, Gárdos G. Transport parameters and stoichiometry of active calcium ion extrusion in intact human red cells. Biochimica Et Biophysica Acta. 464: 93-107. PMID 137747 DOI: 10.1016/0005-2736(77)90373-X  0.312
1976 Sarkadi B, Szász I, Gárdos G. The use of ionophores of rapid loading of human red cells with radioactive cations for cation-pump studies. The Journal of Membrane Biology. 26: 357-370. PMID 58995 DOI: 10.1007/Bf01868883  0.334
Low-probability matches (unlikely to be authored by this person)
2001 Karászi E, Jakab K, Homolya L, Szakács G, Holló Z, Telek B, Kiss A, Rejtô L, Nahajevszky S, Sarkadi B, Kappelmayer J. Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia. British Journal of Haematology. 112: 308-14. PMID 11167823 DOI: 10.1046/J.1365-2141.2001.02554.X  0.296
1989 Tordai A, Sarkadi B, Görög G, Gárdos G. Inhibition of the CD3-mediated calcium signal by protein kinase C activators in human T (Jurkat) lymphoblastoid cells. Immunology Letters. 20: 47-52. PMID 2785492 DOI: 10.1016/0165-2478(89)90067-9  0.296
2016 Pálóczi J, Varga ZV, Apáti Á, Szebényi K, Sarkadi B, Madonna R, De Caterina R, Csont T, Eschenhagen T, Ferdinandy P, Görbe A. Exogenous Nitric Oxide Protects Human Embryonic Stem Cell-Derived Cardiomyocytes against Ischemia/Reperfusion Injury. Oxidative Medicine and Cellular Longevity. 2016: 4298945. PMID 27403231 DOI: 10.1155/2016/4298945  0.295
2015 Szebényi K, Füredi A, Kolacsek O, Csohány R, Prókai Á, Kis-Petik K, Szabó A, Bősze Z, Bender B, Tóvári J, Enyedi Á, Orbán TI, Apáti Á, Sarkadi B. Visualization of Calcium Dynamics in Kidney Proximal Tubules. Journal of the American Society of Nephrology : Jasn. 26: 2731-40. PMID 25788535 DOI: 10.1681/Asn.2014070705  0.295
2014 Paloczi J, Varga Z, Apati A, Szebenyi N, Sarkadi B, Madonna R, Csont T, Ferdinandy P, Gorbe A. P590The NO-donor SNAP exerts cardioprotection against ischemia/reperfusion injury in human embryonic stem cell-derived cardiomyocytes Cardiovascular Research. 103. DOI: 10.1093/Cvr/Cvu098.20  0.286
2014 Kolacsek O, Erdei Z, Apáti A, Sándor S, Izsvák Z, Ivics Z, Sarkadi B, Orbán TI. Excision efficiency is not strongly coupled to transgenic rate: cell type-dependent transposition efficiency of sleeping beauty and piggyBac DNA transposons. Human Gene Therapy Methods. 25: 241-52. PMID 25045962 DOI: 10.1089/Hgtb.2013.149  0.284
1988 Magócsi M, Enyedi Á, Sarkadi B, Gárdos G. Effects of phosphoinositides on calcium movements in human platelet membrane vesicles Biochimica Et Biophysica Acta. 944: 202-212. PMID 2846054 DOI: 10.1016/0005-2736(88)90433-6  0.284
1978 Szász I, Sarkadi B, Gárdos G. Changes in the Ca2+-Transport Processes of Red Cells during Cold Storage in ACD British Journal of Haematology. 39: 559-568. PMID 151553 DOI: 10.1111/J.1365-2141.1978.Tb03626.X  0.281
2023 Broca-Brisson L, Harati R, Disdier C, Mozner O, Gaston-Breton R, Maïza A, Costa N, Guyot AC, Sarkadi B, Apati A, Skelton MR, Madrange L, Yates F, Armengaud J, Hamoudi R, et al. Deciphering neuronal deficit and protein profile changes in human brain organoids from patients with creatine transporter deficiency. Elife. 12. PMID 37830910 DOI: 10.7554/eLife.88459  0.28
2004 Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE, Sarkadi B, Sorrentino BP, Schuetz JD. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. The Journal of Biological Chemistry. 279: 24218-25. PMID 15044468 DOI: 10.1074/Jbc.M313599200  0.279
2020 Kovacsics D, Brózik A, Tihanyi B, Matula Z, Borsy A, Mészáros N, Szabó E, Németh E, Fóthi Á, Zámbó B, Szüts D, Várady G, Orbán TI, Apáti Á, Sarkadi B. Precisely Targeted Reporters Reveal ABCG2 Regulation in Live Lung Cancer Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.09677  0.275
1993 Papp B, Pászty K, Kovács T, Sarkadi B, Gárdos G, Enouf J, Enyedi Á. Characterization of the inositol trisphosphate-sensitive and insensitive calcium stores by selective inhibition of the endoplasmic reticulum-type calcium pump isoforms in isolated platelet membrane vesicles. Cell Calcium. 14: 531-538. PMID 8402836 DOI: 10.1016/0143-4160(93)90074-G  0.273
2021 Telbisz Á, Ambrus C, Mózner O, Szabó E, Várady G, Bakos É, Sarkadi B, Özvegy-Laczka C. Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters. Pharmaceutics. 13. PMID 33435273 DOI: 10.3390/pharmaceutics13010081  0.273
2022 Pálinkás M, Szabó E, Kulin A, Mózner O, Rásonyi R, Juhász P, Nagy K, Várady G, Vörös D, Zámbó B, Sarkadi B, Poór G. Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia. Clinical and Experimental Medicine. PMID 35939175 DOI: 10.1007/s10238-022-00848-7  0.271
2019 Oláh A, Ruppert M, Orbán TI, Apáti Á, Sarkadi BZ, Merkely B, Radovits T. Hemodynamic characterization of a transgenic rat strain stably expressing the calcium sensor protein GCaMP2. American Journal of Physiology. Heart and Circulatory Physiology. PMID 30875251 DOI: 10.1152/Ajpheart.00074.2019  0.271
1991 Sarkadi B, Tordai A, Homolya L, Scharff O, Gárdos G. Calcium influx and intracellular calcium release in anti-CD3 antibody-stimulated and thapsigargin-treated human T lymphoblasts. The Journal of Membrane Biology. 123: 9-21. PMID 1723105 DOI: 10.1007/Bf01993958  0.269
2020 Thomas C, Aller SG, Beis K, Carpenter EP, Chang G, Chen L, Dassa E, Dean M, Duong Van Hoa F, Ekiert D, Ford R, Gaudet R, Gong X, Holland IB, Huang Y, ... ... Sarkadi B, et al. Structural and functional diversity calls for a new classification of ABC transporters. Febs Letters. PMID 32978974 DOI: 10.1002/1873-3468.13935  0.266
2016 Szepesi Á, Matula Z, Szigeti A, Várady G, Szalma J, Szabó G, Uher F, Sarkadi B, Német K. In Vitro Characterization of Human Mesenchymal Stem Cells Isolated from Different Tissues with a Potential to Promote Complex Bone Regeneration. Stem Cells International. 2016: 3595941. PMID 27999599 DOI: 10.1155/2016/3595941  0.263
1979 Sarkadi B, Szász I, Gárdos G. Comments on: On the red blood cell Ca2+-pump: an estimate of stoichiometry. The Journal of Membrane Biology. 46: 183-184. PMID 156258 DOI: 10.1007/Bf01961380  0.261
1987 Hunyady L, Sarkadi B, Cragoe EJ, Spät A, Gárdos G. Activation of sodium-proton exchange is not a prerequisite for Ca2+ mobilization and aggregation in human platelets Febs Letters. 225: 72-76. PMID 2826247 DOI: 10.1016/0014-5793(87)81133-X  0.26
2018 Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, ... ... Sarkadi B, et al. Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nature Communications. 9: 5398. PMID 30568248 DOI: 10.1038/S41467-018-07917-0  0.259
1990 Kovács T, Tordai A, Szász I, Sarkadi B, Gárdos G. Membrane depolarization inhibits thrombin-induced calcium influx and aggregation in human platelets Febs Letters. 266: 171-174. PMID 1694785 DOI: 10.1016/0014-5793(90)81532-S  0.258
2008 Szakács G, Váradi A, Ozvegy-Laczka C, Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Discovery Today. 13: 379-93. PMID 18468555 DOI: 10.1016/j.drudis.2007.12.010  0.257
2017 Szabó Z, Héja L, Szalay G, Kékesi O, Füredi A, Szebényi K, Dobolyi Á, Orbán TI, Kolacsek O, Tompa T, Miskolczy Z, Biczók L, Rózsa B, Sarkadi B, Kardos J. Extensive astrocyte synchronization advances neuronal coupling in slow wave activity in vivo. Scientific Reports. 7: 6018. PMID 28729692 DOI: 10.1038/S41598-017-06073-7  0.251
2019 Sarkadi B, Baghy K, Sápi Z, Nyirő G, Likó I, Patócs A. Germline Mutation Detected in a Multiple Endocrine Neoplasia Type 2 Case With Codon 634 Mutation. Frontiers in Genetics. 10: 544. PMID 31263477 DOI: 10.3389/Fgene.2019.00544  0.251
1989 Magócsi M, Sarkadi B, Kovács T, Gárdos G. Thrombin-induced activation of calcium transport pathways and their role in platelet functions Biochimica Et Biophysica Acta. 984: 88-96. PMID 2548622 DOI: 10.1016/0005-2736(89)90346-5  0.246
2012 Schamberger A, Sarkadi B, Orban TI. Human mirtrons can express functional microRNAs simultaneously from both arms in a flanking exon-independent manner. Rna Biology. 9: 1177-85. PMID 23018783 DOI: 10.4161/Rna.21359  0.243
2019 Sarkadi B, Patócs A. Hereditary Diseases Predisposing to Pheochromocytoma (VHL, NF-1, Paraganglioma Syndromes, and Novel Genes). Experientia Supplementum (2012). 111: 129-147. PMID 31588531 DOI: 10.1007/978-3-030-25905-1_8  0.242
2020 Guragossian N, Belhani B, Moreno A, Nunes MT, Gonzalez-Lobato L, Marminon C, Berthier L, Rocio Andrade Pires AD, Özvegy-Laczka C, Sarkadi B, Terreux R, Bouaziz Z, Berredjem M, Jose J, Di Pietro A, et al. Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2. European Journal of Medicinal Chemistry. 113017. PMID 33223263 DOI: 10.1016/j.ejmech.2020.113017  0.239
2018 Sarkadi B, Grolmusz VK, Butz H, Kövesdi A, Likó I, Nyirő G, Igaz P, Patócs A. [Evolution of molecular genetic methods in the clinical diagnosis of hereditary endocrine tumour syndromes]. Orvosi Hetilap. 159: 285-292. PMID 29429353 DOI: 10.1556/650.2018.31036  0.234
2011 Várady G, Sarkadi B, Fátyol K. TTRAP is a novel component of the non-canonical TRAF6-TAK1 TGF-β signaling pathway. Plos One. 6: e25548. PMID 21980489 DOI: 10.1371/Journal.Pone.0025548  0.231
2020 Reé D, Borsy A, Fóthi Á, Orbán TI, Várady G, Erdei Z, Sarkadi B, Réthelyi J, Varga N, Apáti Á. Establishing a human embryonic stem cell clone with a heterozygous mutation in the DGCR8 gene. Stem Cell Research. 50: 102134. PMID 33360445 DOI: 10.1016/j.scr.2020.102134  0.226
2013 Kolacsek O, Krízsik V, Schamberger A, Erdei Z, Apáti A, Várady G, Mátés L, Izsvák Z, Ivics Z, Sarkadi B, Orbán TI. Correction: Reliable transgene-independent method for determining sleeping beauty transposon copy numbers. Mobile Dna. 4: 11. PMID 23497459 DOI: 10.1186/1759-8753-4-11  0.225
2010 Schneider CK, Salmikangas P, Jilma B, Flamion B, Todorova LR, Paphitou A, Haunerova I, Maimets T, Trouvin JH, Flory E, Tsiftsoglou A, Sarkadi B, Gudmundsson K, et al. Challenges with advanced therapy medicinal products and how to meet them. Nature Reviews. Drug Discovery. 9: 195-201. PMID 20190786 DOI: 10.1038/Nrd3052  0.225
2011 Kolacsek O, Krízsik V, Schamberger A, Erdei Z, Apáti A, Várady G, Mátés L, Izsvák Z, Ivics Z, Sarkadi B, Orbán TI. Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers. Mobile Dna. 2: 5. PMID 21371313 DOI: 10.1186/1759-8753-2-5  0.224
1982 Gárdos G, Sarkadi B, Enyedi Á. Control of Ca2+ pumps Trends in Biochemical Sciences. 7: 242. DOI: 10.1016/0968-0004(82)90032-9  0.215
1998 Tordai A, Andrikovics H, Kalmár L, Rajczy K, Pénzes M, Sarkadi B, Klein I, Váradi A. High Frequency Of The Haemochromatosis C282Y Mutation In Hungary Could Argue Against A Celtic Origin Of The Mutation Journal of Medical Genetics. 35: 878-879. PMID 9783719 DOI: 10.1136/Jmg.35.10.878-A  0.206
2023 Sarkadi B. Cancer stem cells in drug resistance: an introduction to the e-book covering the special issue on the "Cancer Stem Cells and Drug Resistance". Cancer Drug Resistance (Alhambra, Calif.). 6: 239-241. PMID 37457124 DOI: 10.20517/cdr.2023.23  0.201
2021 Krokker L, Szabó B, Németh K, Tóháti R, Sarkadi B, Mészáros K, Patócs A, Butz H. Three Dimensional Cell Culturing for Modeling Adrenal and Pituitary Tumors. Pathology Oncology Research : Por. 27: 640676. PMID 34257605 DOI: 10.3389/pore.2021.640676  0.14
2023 Mózner O, Moldvay J, Szabó KS, Vaskó D, Domján J, Ács D, Ligeti Z, Fehér C, Hirsch E, Puskás L, Stahl C, Frey M, Sarkadi B. Application of a Receptor-Binding-Domain-Based Simple Immunoassay for Assessing Humoral Immunity against Emerging SARS-CoV-2 Virus Variants. Biomedicines. 11. PMID 38137414 DOI: 10.3390/biomedicines11123193  0.133
2021 Sarkadi B, Liko I, Nyiro G, Igaz P, Butz H, Patocs A. Analytical Performance of NGS-Based Molecular Genetic Tests Used in the Diagnostic Workflow of Pheochromocytoma/Paraganglioma. Cancers. 13. PMID 34439371 DOI: 10.3390/cancers13164219  0.115
2022 Sarkadi B, Saskoi E, Butz H, Patocs A. Genetics of Pheochromocytomas and Paragangliomas Determine the Therapeutical Approach. International Journal of Molecular Sciences. 23. PMID 35163370 DOI: 10.3390/ijms23031450  0.092
2022 Ferenci T, Sarkadi B. RBD-specific antibody responses after two doses of BBIBP-CorV (Sinopharm, Beijing CNBG) vaccine. Bmc Infectious Diseases. 22: 87. PMID 35073866 DOI: 10.1186/s12879-022-07069-z  0.025
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