Isaiah J. Fidler - Publications

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology, Oncology

82 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Lee HJ, Hanibuchi M, Kim SJ, Yu H, Kim MS, He J, Langley RR, Lehembre F, Regenass U, Fidler IJ. Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel. Neuro-Oncology. 18: 486-496. PMID 26995790 DOI: 10.1093/neuonc/now037  0.36
2015 Kim SJ, Lee HJ, Kim SW, Choi HJ, He J, Wu Q, Aldape KD, Weinberg JS, Yung WK, Conrad CA, Langley RR, Lehembre F, Regenass U, Fidler IJ. Macitentan, a dual endothelin receptor antagonist, in combination with temozolomide leads to glioblastoma regression and long-term survival in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26106074 DOI: 10.1158/1078-0432.CCR-14-3195  0.36
2015 Kim SW, Kim SJ, Langley RR, Fidler IJ. Modulation of the cancer cell transcriptome by culture media formulations and cell density. International Journal of Oncology. 46: 2067-75. PMID 25776572 DOI: 10.3892/ijo.2015.2930  0.36
2015 Shoshan E, Mobley AK, Braeuer RR, Kamiya T, Huang L, Vasquez ME, Salameh A, Lee HJ, Kim SJ, Ivan C, Velazquez-Torres G, Nip KM, Zhu K, Brooks D, Jones SJ, ... ... Fidler IJ, et al. Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Nature Cell Biology. 17: 311-21. PMID 25686251 DOI: 10.1038/ncb3110  0.36
2015 Chen J, Lee HJ, Wu X, Huo L, Kim SJ, Xu L, Wang Y, He J, Bollu LR, Gao G, Su F, Briggs J, Liu X, Melman T, Asara JM, ... Fidler IJ, et al. Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain. Cancer Research. 75: 554-65. PMID 25511375 DOI: 10.1158/0008-5472.CAN-14-2268  0.52
2014 Hanibuchi M, Kim SJ, Fidler IJ, Nishioka Y. The molecular biology of lung cancer brain metastasis: an overview of current comprehensions and future perspectives. The Journal of Medical Investigation : Jmi. 61: 241-53. PMID 25264041 DOI: DN/JST.JSTAGE/jmi/61.241  0.36
2014 Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, ... ... Fidler IJ, et al. Hematogenous metastasis of ovarian cancer: rethinking mode of spread. Cancer Cell. 26: 77-91. PMID 25026212 DOI: 10.1016/j.ccr.2014.05.002  0.36
2014 Kim SW, Choi HJ, Lee HJ, He J, Wu Q, Langley RR, Fidler IJ, Kim SJ. Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells. Neuro-Oncology. 16: 1585-98. PMID 25008093 DOI: 10.1093/neuonc/nou128  0.36
2013 Langley RR, Fidler IJ. The biology of brain metastasis. Clinical Chemistry. 59: 180-9. PMID 23115057 DOI: 10.1373/clinchem.2012.193342  0.36
2013 Yokoi K, Godin B, Oborn CJ, Alexander JF, Liu X, Fidler IJ, Ferrari M. Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers. Cancer Letters. 334: 319-27. PMID 23000514 DOI: 10.1016/j.canlet.2012.09.001  0.36
2012 Kim SJ, Kim JS, Kim SW, Yun SJ, He J, Brantley E, Fan D, Strickner P, Lehembre F, Regenass U, Fidler IJ. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist. Translational Oncology. 5: 39-47. PMID 22348175  0.52
2011 Park ES, Kim SJ, Kim SW, Yoon SL, Leem SH, Kim SB, Kim SM, Park YY, Cheong JH, Woo HG, Mills GB, Fidler IJ, Lee JS. Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis. Proceedings of the National Academy of Sciences of the United States of America. 108: 17456-61. PMID 21987811 DOI: 10.1073/pnas.1114210108  0.36
2011 Guo L, Fan D, Zhang F, Price JE, Lee JS, Marchetti D, Fidler IJ, Langley RR. Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar. The American Journal of Pathology. 178: 2357-66. PMID 21514446 DOI: 10.1016/j.ajpath.2011.01.047  0.52
2011 Yokoi K, Hawke D, Oborn CJ, Jang JY, Nishioka Y, Fan D, Kim SW, Kim SJ, Fidler IJ. Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer. Translational Oncology. 4: 83-91. PMID 21461171  0.52
2011 Kim SJ, Kim JS, Kim SW, Brantley E, Yun SJ, He J, Maya M, Zhang F, Wu Q, Lehembre F, Regenass U, Fidler IJ. Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer Neoplasia. 13: 167-179. PMID 21403842 DOI: 10.1593/neo.10806  0.36
2011 Kim SJ, Kim JS, Park ES, Lee JS, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung MC, Fidler IJ. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy. Neoplasia (New York, N.Y.). 13: 286-98. PMID 21390191  0.52
2011 Langley RR, Fidler IJ. The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organs. International Journal of Cancer. 128: 2527-35. PMID 21365651 DOI: 10.1002/ijc.26031  0.36
2011 Weihua Z, Lin Q, Ramoth AJ, Fan D, Fidler IJ. Formation of solid tumors by a single multinucleated cancer cell. Cancer. 117: 4092-9. PMID 21365635 DOI: 10.1002/cncr.26021  0.52
2011 Kim SW, Kim JS, Papadopoulos J, Choi HJ, He J, Maya M, Langley RR, Fan D, Fidler IJ, Kim SJ. Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse. International Immunopharmacology. 11: 862-72. PMID 21251905 DOI: 10.1016/j.intimp.2011.01.004  0.52
2010 Brantley EC, Guo L, Zhang C, Lin Q, Yokoi K, Langley RR, Kruzel E, Maya M, Kim SW, Kim SJ, Fan D, Fidler IJ. Nitric oxide-mediated tumoricidal activity of murine microglial cells. Translational Oncology. 3: 380-8. PMID 21151477 DOI: 10.1593/tlo.10208  0.52
2010 Lin Q, Balasubramanian K, Fan D, Kim SJ, Guo L, Wang H, Bar-Eli M, Aldape KD, Fidler IJ. Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels. Neoplasia (New York, N.Y.). 12: 748-54. PMID 20824051  0.52
2010 Fidler IJ, Balasubramanian K, Lin Q, Kim SW, Kim SJ. The brain microenvironment and cancer metastasis. Molecules and Cells. 30: 93-8. PMID 20799011 DOI: 10.1007/s10059-010-0133-9  0.52
2010 Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, ... ... Fidler IJ, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Science Signaling. 3: ra9. PMID 20145209 DOI: 10.1126/scisignal.2000590  0.52
2010 Rebhun RB, Cheng H, Gershenwald JE, Fan D, Fidler IJ, Langley RR. Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Neoplasia (New York, N.Y.). 12: 173-82. PMID 20126475  0.52
2009 Langley RR, Fan D, Guo L, Zhang C, Lin Q, Brantley EC, McCarty JH, Fidler IJ. Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis. International Journal of Oncology. 35: 665-72. PMID 19724901 DOI: 10.3892/ijo-00000378  0.52
2009 Kim SJ, Kim JS, Papadopoulos J, Wook Kim S, Maya M, Zhang F, He J, Fan D, Langley R, Fidler IJ. Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis. The American Journal of Pathology. 174: 1972-80. PMID 19349357 DOI: 10.2353/ajpath.2009.080819  0.52
2008 Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/jbc.M804595200  0.36
2008 Sasaki T, Nakamura T, Rebhun RB, Cheng H, Hale KS, Tsan RZ, Fidler IJ, Langley RR. Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model. The American Journal of Pathology. 173: 205-16. PMID 18583324 DOI: 10.2353/ajpath.2008.071147  0.36
2008 Kuwai T, Nakamura T, Sasaki T, Kim SJ, Fan D, Villares GJ, Zigler M, Wang H, Bar-Eli M, Kerbel RS, Fidler IJ. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors. Neoplasia (New York, N.Y.). 10: 489-500. PMID 18472966  0.52
2008 Weihua Z, Tsan R, Huang WC, Wu Q, Chiu CH, Fidler IJ, Hung MC. Survival of cancer cells is maintained by EGFR independent of its kinase activity. Cancer Cell. 13: 385-93. PMID 18455122 DOI: 10.1016/j.ccr.2008.03.015  0.52
2008 Kuwai T, Nakamura T, Sasaki T, Kitadai Y, Kim JS, Langley RR, Fan D, Wang X, Do KA, Kim SJ, Fidler IJ. Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy. Clinical & Experimental Metastasis. 25: 477-89. PMID 18324358 DOI: 10.1007/s10585-008-9153-7  0.52
2008 Rebhun RB, Lazar AJ, Fidler IJ, Gershenwald JE. Impact of sentinel lymphadenectomy on survival in a murine model of melanoma. Clinical & Experimental Metastasis. 25: 191-9. PMID 18264782 DOI: 10.1007/s10585-008-9141-y  0.36
2008 Kuwai T, Nakamura T, Kim SJ, Sasaki T, Kitadai Y, Langley RR, Fan D, Hamilton SR, Fidler IJ. Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. The American Journal of Pathology. 172: 358-66. PMID 18202197 DOI: 10.2353/ajpath.2008.070625  0.52
2007 Sasaki T, Kitadai Y, Nakamura T, Kim JS, Tsan RZ, Kuwai T, Langley RR, Fan D, Kim SJ, Fidler IJ. Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice. Neoplasia (New York, N.Y.). 9: 1066-77. PMID 18084614  0.52
2007 Nakamura T, Kuwai T, Kim JS, Fan D, Kim SJ, Fidler IJ. Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice. Neoplasia (New York, N.Y.). 9: 979-86. PMID 18030366  0.52
2007 Wu W, O'Reilly MS, Langley RR, Tsan RZ, Baker CH, Bekele N, Tang XM, Onn A, Fidler IJ, Herbst RS. Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice. Molecular Cancer Therapeutics. 6: 2652-63. PMID 17913856 DOI: 10.1158/1535-7163.MCT-06-0759  0.36
2007 Mathew P, Thall PF, Bucana CD, Oh WK, Morris MJ, Jones DM, Johnson MM, Wen S, Pagliaro LC, Tannir NM, Tu SM, Meluch AA, Smith L, Cohen L, Kim SJ, ... ... Fidler IJ, et al. Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5816-24. PMID 17908974 DOI: 10.1158/1078-0432.CCR-07-1269  0.36
2007 Nakamura T, Kuwai T, Kitadai Y, Sasaki T, Fan D, Coombes KR, Kim SJ, Fidler IJ. Zonal heterogeneity for gene expression in human pancreatic carcinoma. Cancer Research. 67: 7597-604. PMID 17699763 DOI: 10.1158/0008-5472.CAN-07-0874  0.52
2007 Langley RR, Fidler IJ. Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis. Endocrine Reviews. 28: 297-321. PMID 17409287 DOI: 10.1210/er.2006-0027  0.36
2007 Wu W, Onn A, Isobe T, Itasaka S, Langley RR, Shitani T, Shibuya K, Komaki R, Ryan AJ, Fidler IJ, Herbst RS, O'Reilly MS. Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade. Molecular Cancer Therapeutics. 6: 471-83. PMID 17308046 DOI: 10.1158/1535-7163.MCT-06-0416  0.36
2007 Fidler IJ, Kim SJ, Langley RR. The role of the organ microenvironment in the biology and therapy of cancer metastasis. Journal of Cellular Biochemistry. 101: 927-36. PMID 17177290 DOI: 10.1002/jcb.21148  0.36
2006 Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Fidler IJ. Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. The American Journal of Pathology. 169: 2054-65. PMID 17148668 DOI: 10.2353/ajpath.2006.060653  0.32
2006 Busby JE, Kim SJ, Yazici S, Nakamura T, Kim JS, He J, Maya M, Wang X, Do KA, Fan D, Fidler IJ. Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells. The Prostate. 66: 1788-98. PMID 17013882 DOI: 10.1002/pros.20519  0.52
2006 Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Hamilton SR, Fidler IJ. Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential. International Journal of Cancer. 119: 2567-74. PMID 16988946 DOI: 10.1002/ijc.22229  0.32
2006 Rebhun RB, Langley RR, Yokoi K, Fan D, Gershenwald JE, Fidler IJ. Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis. Neoplasia (New York, N.Y.). 8: 747-57. PMID 16984732 DOI: 10.1593/neo.06322  0.52
2006 Kim SJ, Uehara H, Yazici S, Busby JE, Nakamura T, He J, Maya M, Logothetis C, Mathew P, Wang X, Do KA, Fan D, Fidler IJ. Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer. Journal of the National Cancer Institute. 98: 783-93. PMID 16757703 DOI: 10.1093/jnci/djj211  0.52
2005 Weihua Z, Tsan R, Schroit AJ, Fidler IJ. Apoptotic cells initiate endothelial cell sprouting via electrostatic signaling. Cancer Research. 65: 11529-35. PMID 16357162 DOI: 10.1158/0008-5472.CAN-05-2718  0.52
2005 Cheng H, Langley RR, Wu Q, Wu W, Feng J, Tsan R, Fan D, Fidler IJ. Construction of a novel constitutively active chimeric EGFR to identify new targets for therapy. Neoplasia (New York, N.Y.). 7: 1065-72. PMID 16354589  0.52
2005 Nilsson MB, Langley RR, Fidler IJ. Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine. Cancer Research. 65: 10794-800. PMID 16322225 DOI: 10.1158/0008-5472.CAN-05-0623  0.36
2005 Yokoi K, Sasaki T, Bucana CD, Fan D, Baker CH, Kitadai Y, Kuwai T, Abbruzzese JL, Fidler IJ. Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model. Cancer Research. 65: 10371-80. PMID 16288027 DOI: 10.1158/0008-5472.CAN-05-1698  0.52
2005 Yokoi K, Shih LCN, Kobayashi R, Koomen J, Hawke D, Li D, Hamilton SR, Abbruzzese JL, Coombes KR, Fidler IJ. Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer International Journal of Oncology. 27: 1361-1369. PMID 16211233  0.36
2005 Yokoi K, Kim SJ, Thaker P, Yazici S, Nam DH, He J, Sasaki T, Chiao PJ, Sclabas GM, Abbruzzese JL, Hamilton SR, Fidler IJ. Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia (New York, N.Y.). 7: 696-704. PMID 16026649  0.36
2005 Thaker PH, Yazici S, Nilsson MB, Yokoi K, Tsan RZ, He J, Kim SJ, Fidler IJ, Sood AK. Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4923-33. PMID 16000591 DOI: 10.1158/1078-0432.CCR-04-2060  0.36
2005 Younes MN, Yigitbasi OG, Park YW, Kim SJ, Jasser SA, Hawthorne VS, Yazici YD, Mandal M, Bekele BN, Bucana CD, Fidler IJ, Myers JN. Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation. Cancer Research. 65: 4716-27. PMID 15930290 DOI: 10.1158/0008-5472.CAN-04-4196  0.36
2005 Yokoi K, Thaker PH, Yazici S, Rebhun RR, Nam DH, He J, Kim SJ, Abbruzzese JL, Hamilton SR, Fidler IJ. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer Research. 65: 3716-25. PMID 15867367 DOI: 10.1158/0008-5472.CAN-04-3700  0.36
2005 Kim SJ, Uehara H, Yazici S, He J, Langley RR, Mathew P, Fan D, Fidler IJ. Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer. Cancer Research. 65: 3707-15. PMID 15867366 DOI: 10.1158/0008-5472.CAN-04-3601  0.52
2005 Sclabas GM, Fujioka S, Schmidt C, Li Z, Frederick WA, Yang W, Yokoi K, Evans DB, Abbruzzese JL, Hess KR, Zhang W, Fidler IJ, Chiao PJ. Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 440-9. PMID 15701826  0.36
2005 Uehara H, Troncoso P, Johnston D, Bucana CD, Dinney C, Dong Z, Fidler IJ, Pettaway CA. Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage. The Prostate. 64: 40-9. PMID 15651067 DOI: 10.1002/pros.20223  0.32
2005 Cheng H, Cenciarelli C, Nelkin G, Tsan R, Fan D, Cheng-Mayer C, Fidler IJ. Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth. Molecular and Cellular Biology. 25: 44-59. PMID 15601829 DOI: 10.1128/MCB.25.1.44-59.2005  0.52
2004 Yigitbasi OG, Younes MN, Doan D, Jasser SA, Schiff BA, Bucana CD, Bekele BN, Fidler IJ, Myers JN. Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade. Cancer Research. 64: 7977-84. PMID 15520205 DOI: 10.1158/0008-5472.CAN-04-1477  0.32
2004 Mathew P, Thall PF, Jones D, Perez C, Bucana C, Troncoso P, Kim SJ, Fidler IJ, Logothetis C. Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3323-9. PMID 15310776 DOI: 10.1200/JCO.2004.10.116  0.36
2004 Kim SJ, Uehara H, Yazici S, Langley RR, He J, Tsan R, Fan D, Killion JJ, Fidler IJ. Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice. Cancer Research. 64: 4201-8. PMID 15205332 DOI: 10.1158/0008-5472.CAN-03-3763  0.52
2004 Langley RR, Fan D, Tsan RZ, Rebhun R, He J, Kim SJ, Fidler IJ. Activation of the platelet-derived growth factor-receptor enhances survival of murine bone endothelial cells. Cancer Research. 64: 3727-30. PMID 15172974 DOI: 10.1158/0008-5472.CAN-03-3863  0.52
2004 Yokoi K, Fidler IJ. Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2299-306. PMID 15073105  0.36
2004 Apte SM, Bucana CD, Killion JJ, Gershenson DM, Fidler IJ. Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines. Gynecologic Oncology. 93: 78-86. PMID 15047217 DOI: 10.1016/j.ygyno.2003.12.041  0.32
2004 Apte SM, Fan D, Killion JJ, Fidler IJ. Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 897-908. PMID 14871965  0.52
2004 Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS. Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 136-43. PMID 14734462  0.32
2004 Bucana CD, Fidler IJ. Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms. International Journal of Oncology. 24: 19-24. PMID 14654936  0.32
2003 Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ. Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 6534-44. PMID 14695158  0.36
2003 Holsinger FC, Doan DD, Jasser SA, Swan EA, Greenberg JS, Schiff BA, Bekele BN, Younes MN, Bucana CD, Fidler IJ, Myers JN. Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3183-9. PMID 12912971  0.32
2003 McCarty MF, Bielenberg DR, Nilsson MB, Gershenwald JE, Barnhill RL, Ahearne P, Bucana CD, Fidler IJ. Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis. Melanoma Research. 13: 379-87. PMID 12883364 DOI: 10.1097/01.cmr.0000056255.56735.d4  0.36
2003 Langley RR, Ramirez KM, Tsan RZ, Van Arsdall M, Nilsson MB, Fidler IJ. Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis. Cancer Research. 63: 2971-6. PMID 12782605  0.36
2003 Weber KL, Doucet M, Price JE, Baker C, Kim SJ, Fidler IJ. Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice. Cancer Research. 63: 2940-7. PMID 12782601  0.36
2003 Solorzano CC, Hwang R, Baker CH, Bucana CD, Pisters PW, Evans DB, Killion JJ, Fidler IJ. Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1858-67. PMID 12738744  0.32
2003 Ozawa S, Lu W, Bucana CD, Kanayama HO, Shinohara H, Fidler IJ, Dong Z. Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International Journal of Oncology. 22: 977-84. PMID 12684662  0.32
2003 Lu W, Su J, Kim LS, Bucana CD, Donawho C, He J, Fidler IJ, Dong Z. Active specific immunotherapy against occult brain metastasis. Cancer Research. 63: 1345-50. PMID 12649197  0.32
2003 Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, Killion JJ, Logothetis C, Mathew P, Fidler IJ. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. Journal of the National Cancer Institute. 95: 458-70. PMID 12644539  0.52
2003 Kim SJ, Uehara H, Karashima T, Shepherd DL, Killion JJ, Fidler IJ. Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1200-10. PMID 12631626  0.36
2002 McCarty MF, Bielenberg D, Donawho C, Bucana CD, Fidler IJ. Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms. Clinical & Experimental Metastasis. 19: 609-15. PMID 12498390  0.32
2002 Baker CH, Kedar D, McCarty MF, Tsan R, Weber KL, Bucana CD, Fidler IJ. Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas. The American Journal of Pathology. 161: 929-38. PMID 12213721 DOI: 10.1016/S0002-9440(10)64253-8  0.32
2002 McCarty MF, Baker CH, Bucana CD, Fidler IJ. Quantitative and qualitative in vivo angiogenesis assay. International Journal of Oncology. 21: 5-10. PMID 12063542  0.32
1999 Bielenberg DR, McCarty MF, Bucana CD, Yuspa SH, Morgan D, Arbeit JM, Ellis LM, Cleary KR, Fidler IJ. Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells. The Journal of Investigative Dermatology. 112: 802-9. PMID 10233775 DOI: 10.1046/j.1523-1747.1999.00566.x  0.32
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