Isaiah J. Fidler - Publications

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Cell Biology, Oncology

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Year Citation  Score
2019 McGary EC, Weber K, Mills L, Doucet M, Lewis V, Lev DC, Fidler IJ, Bar-Eli M. Editor's Note: Inhibition of Platelet-derived Growth Factor-mediated Proliferation of Osteosarcoma Cells by the Novel Tyrosine Kinase Inhibitor STI571. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 25: 3196. PMID 31092620 DOI: 10.1158/1078-0432.Ccr-19-1101  0.415
2016 Fidler IJ. Commentary on "Tumor Heterogeneity and the Biology of Cancer Invasion and Metastasis". Cancer Research. 76: 3441-2. PMID 27306869 DOI: 10.1158/0008-5472.Can-16-1330  0.359
2016 Lee HJ, Hanibuchi M, Kim SJ, Yu H, Kim MS, He J, Langley RR, Lehembre F, Regenass U, Fidler IJ. Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel. Neuro-Oncology. 18: 486-496. PMID 26995790 DOI: 10.1093/Neuonc/Now037  0.373
2016 Lee HJ, Yu HK, Kim SW, Choi SI, He J, Fidler IJ, Kim SJ. Abstract 737: Transcriptome of glioma growing in the brain is simulated by tumor cells cultured under low oxygen pressure Cancer Research. 76: 737-737. DOI: 10.1158/1538-7445.Am2016-737  0.396
2016 Yu HK, Lee HJ, Zhang F, Wu Q, Fidler IJ, Kim SJ. Abstract 2943: Hypoxia induced resistance to chemotherapy is regulated by the endothelin receptor axis Cancer Research. 76: 2943-2943. DOI: 10.1158/1538-7445.Am2016-2943  0.457
2015 Fidler IJ, Kripke ML. The challenge of targeting metastasis. Cancer Metastasis Reviews. 34: 635-41. PMID 26328524 DOI: 10.1007/S10555-015-9586-9  0.453
2015 Fidler IJ. The Biology of Brain Metastasis: Challenges for Therapy. Cancer Journal (Sudbury, Mass.). 21: 284-93. PMID 26222080 DOI: 10.1097/Ppo.0000000000000126  0.454
2015 Kim SJ, Lee HJ, Kim SW, Choi HJ, He J, Wu Q, Aldape KD, Weinberg JS, Yung WK, Conrad CA, Langley RR, Lehembre F, Regenass U, Fidler IJ. Macitentan, a dual endothelin receptor antagonist, in combination with temozolomide leads to glioblastoma regression and long-term survival in mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26106074 DOI: 10.1158/1078-0432.Ccr-14-3195  0.364
2015 Kim SW, Kim SJ, Langley RR, Fidler IJ. Modulation of the cancer cell transcriptome by culture media formulations and cell density. International Journal of Oncology. 46: 2067-75. PMID 25776572 DOI: 10.3892/Ijo.2015.2930  0.383
2015 Shoshan E, Mobley AK, Braeuer RR, Kamiya T, Huang L, Vasquez ME, Salameh A, Lee HJ, Kim SJ, Ivan C, Velazquez-Torres G, Nip KM, Zhu K, Brooks D, Jones SJ, ... ... Fidler IJ, et al. Reduced adenosine-to-inosine miR-455-5p editing promotes melanoma growth and metastasis. Nature Cell Biology. 17: 311-21. PMID 25686251 DOI: 10.1038/Ncb3110  0.315
2015 Kim MS, Choi HJ, Lee H, He J, We Q, Langley RR, Kim S, Fidler IJ. Abstract 5463: Role of the endothelin axis in astrocyte and endothelial cell mediated chemoprotection of cancer cells Cancer Research. 75: 5463-5463. DOI: 10.1158/1538-7445.Am2015-5463  0.426
2015 Lee HJ, Kim SJ, Yu HK, Kim SW, Wu Q, He J, Fidler IJ. Abstract 5154: Diagnostic serum markers for metastatic brain tumors identified by cross-species hybridization of microarrays in animal models Cancer Research. 75: 5154-5154. DOI: 10.1158/1538-7445.Am2015-5154  0.413
2015 Dai Y, Zhu L, Cho E, Hagiwara A, Faller D, Kim S, Fidler IJ, Amaro M. Abstract 2056: SIRT1 silencing suppresses prostate cancer growth and metastasis in an orthotopic prostate cancer mouse model Cancer Research. 75: 2056-2056. DOI: 10.1158/1538-7445.Am2015-2056  0.395
2014 Hanibuchi M, Kim SJ, Fidler IJ, Nishioka Y. The molecular biology of lung cancer brain metastasis: an overview of current comprehensions and future perspectives. The Journal of Medical Investigation : Jmi. 61: 241-53. PMID 25264041 DOI: 10.2152/Jmi.61.241  0.326
2014 Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, ... ... Fidler IJ, et al. Hematogenous metastasis of ovarian cancer: rethinking mode of spread. Cancer Cell. 26: 77-91. PMID 25026212 DOI: 10.1016/J.Ccr.2014.05.002  0.382
2014 Kim SW, Choi HJ, Lee HJ, He J, Wu Q, Langley RR, Fidler IJ, Kim SJ. Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells. Neuro-Oncology. 16: 1585-98. PMID 25008093 DOI: 10.1093/Neuonc/Nou128  0.426
2014 Shoshan E, Mobley A, Braeuer R, Kamiya T, Huang L, Vasquez M, Jeong LH, kim SJ, Calin G, Sood A, Markel G, Fidler I, Bar-Eli M. Abstract 4969: Hypo adenosine-to-inosine editing of microRNA-455 promotes melanoma metastasis Cancer Research. 74: 4969-4969. DOI: 10.1158/1538-7445.Am2014-4969  0.338
2014 Kim SW, Kim SJ, Lee H, He J, Wu Q, Lawson EJ, Fidler IJ. Abstract 4878: Modification of gene expression in tumor cells by the culture microenvironment Cancer Research. 74: 4878-4878. DOI: 10.1158/1538-7445.Am2014-4878  0.391
2014 Lee HJ, Kim SJ, Kim SW, He J, Wu Q, Lawson EJ, Lehembre F, Regenass U, Fidler IJ. Abstract 3779: Treatment of experimental brain metastasis of human breast cancer by macitentan, a dual antagonist of endothelin receptors combined with paclitaxel Cancer Research. 74: 3779-3779. DOI: 10.1158/1538-7445.Am2014-3779  0.458
2013 Langley RR, Fidler IJ. The biology of brain metastasis. Clinical Chemistry. 59: 180-9. PMID 23115057 DOI: 10.1373/Clinchem.2012.193342  0.413
2013 Yokoi K, Godin B, Oborn CJ, Alexander JF, Liu X, Fidler IJ, Ferrari M. Porous silicon nanocarriers for dual targeting tumor associated endothelial cells and macrophages in stroma of orthotopic human pancreatic cancers. Cancer Letters. 334: 319-27. PMID 23000514 DOI: 10.1016/J.Canlet.2012.09.001  0.456
2013 Kim SJ, Kim SW, Choi HJ, Lee HJ, Lehembre F, He J, Regenass U, Conrad CA, Yung WK, Fidler IJ. Abstract 5481: Therapy of human LN229 glioblastoma growing in the brain of nude mice by Macitentan, a dual endothelin receptor A and B antagonist, combined with Temozolomide. Cancer Research. 73: 5481-5481. DOI: 10.1158/1538-7445.Am2013-5481  0.424
2013 Kim SW, Kim SJ, Choi HJ, Lee H, He J, Wu Q, Lawson EJ, Fidler IJ. Abstract 4951: The role of endothelin axis signaling pathway in astrocyte mediated chemoprotection of tumor cells. Cancer Research. 73: 4951-4951. DOI: 10.1158/1538-7445.Am2013-4951  0.478
2013 Pradeep S, Wook K, Nishimura M, Raghavan P, Pecot C, Lopez G, Fidler I, Sood A. Abstract 408: Hematogenous metastasis in ovarian cancer: Importance of the ErbB3/NRG axis. Cancer Research. 73: 408-408. DOI: 10.1158/1538-7445.Am2013-408  0.47
2012 Fidler IJ. Biological heterogeneity of cancer: implication to therapy. Human Vaccines & Immunotherapeutics. 8: 1141-2. PMID 22854675 DOI: 10.4161/Hv.19643  0.46
2012 Kim SJ, Kim JS, Kim SW, Yun SJ, He J, Brantley E, Fan D, Strickner P, Lehembre F, Regenass U, Fidler IJ. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist. Translational Oncology. 5: 39-47. PMID 22348175 DOI: 10.1593/Tlo.11286  0.463
2012 Fujimaki T, Ellis L, Bucana C, Radinsky R, Price J, Fidler I. Simultaneous radiolabel, genetic tagging and proliferation assays to study the organ distribution and fate of metastatic cells. International Journal of Oncology. 2: 895-901. PMID 21573644 DOI: 10.3892/ijo.2.6.895  0.379
2012 Wilmanns C, Fan D, Obrian C, Radinsky R, Bucana C, Tsan R, Fidler I. Modulation of Doxorubicin sensitivity and level of p-glycoprotein expression in human colon-carcinoma cells by ectopic and orthotopic environments in nude-mice. International Journal of Oncology. 3: 413-22. PMID 21573380 DOI: 10.3892/Ijo.3.3.413  0.356
2012 Berry K, Siegal G, Boyd J, Singh R, Fidler I. Development of a metastatic model for human endometrial carcinoma using orthotopic implantation in nude-mice. International Journal of Oncology. 4: 1163-71. PMID 21567033 DOI: 10.3892/ijo.4.6.1163  0.379
2012 Singh R, Bucana C, Llansa N, Sanchez R, Fidler I. Cell density-dependent modulation of basic fibroblast growth factor expression by human interferon-beta. International Journal of Oncology. 8: 649-56. PMID 21544408 DOI: 10.3892/Ijo.8.4.649  0.356
2012 Fan D, Beltran P, Wang Y, Bucana C, Yoon S, Deguzman A, Fidler I. Cell density-dependent regulation of mdr-1 gene expression in murine colon cancer cells. International Journal of Oncology. 9: 865-78. PMID 21541589 DOI: 10.3892/Ijo.9.5.865  0.431
2012 Kim SJ, Kim JS, Kim SW, Yun SJ, He J, Brantley E, Fan D, Strickner P, Lehembre F, Regenass U, Fidler IJ. Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist Translational Oncology. 5: 39-47. DOI: 10.1593/tlo.11286  0.357
2012 Hanibuchi M, Kim S, Otsuka K, Tabata S, Kuramoto T, Goto H, Nishioka Y, Fidler IJ. Eradication of experimental brain metastases of human non-small cell lung cancer by macitentan, a dual antagonist of the endothelin A and B receptor, combined with paclitaxel. Journal of Clinical Oncology. 30: 92-92. DOI: 10.1200/Jco.2012.30.30_Suppl.92  0.456
2012 Park ES, Kim S, Kim SW, Yoon S, Leem S, Kim S, Kim SM, Park Y, Cheong J, Woo HG, Mills GB, Fidler IJ, Lee J. Abstract 4283: Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis Cancer Research. 72: 4283-4283. DOI: 10.1158/1538-7445.Am2012-4283  0.451
2012 Yokoi K, Ven AVd, Alexander JF, Bai L, Liu X, Fidler IJ, Ferrari M, Godin B. Abstract 2453: Overcoming transport barriers in liver metastasis with multi-stage nanovectors (MSV) Cancer Research. 72: 2453-2453. DOI: 10.1158/1538-7445.Am2012-2453  0.41
2011 Park ES, Kim SJ, Kim SW, Yoon SL, Leem SH, Kim SB, Kim SM, Park YY, Cheong JH, Woo HG, Mills GB, Fidler IJ, Lee JS. Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis. Proceedings of the National Academy of Sciences of the United States of America. 108: 17456-61. PMID 21987811 DOI: 10.1073/Pnas.1114210108  0.458
2011 Guo L, Fan D, Zhang F, Price JE, Lee JS, Marchetti D, Fidler IJ, Langley RR. Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar. The American Journal of Pathology. 178: 2357-66. PMID 21514446 DOI: 10.1016/J.Ajpath.2011.01.047  0.446
2011 Yokoi K, Hawke D, Oborn CJ, Jang JY, Nishioka Y, Fan D, Kim SW, Kim SJ, Fidler IJ. Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer. Translational Oncology. 4: 83-91. PMID 21461171 DOI: 10.1593/Tlo.10202  0.384
2011 Kim SJ, Kim JS, Kim SW, Brantley E, Yun SJ, He J, Maya M, Zhang F, Wu Q, Lehembre F, Regenass U, Fidler IJ. Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer Neoplasia. 13: 167-179. PMID 21403842 DOI: 10.1593/Neo.10806  0.482
2011 Kim SJ, Kim JS, Park ES, Lee JS, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung MC, Fidler IJ. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy. Neoplasia (New York, N.Y.). 13: 286-98. PMID 21390191 DOI: 10.1593/Neo.11112  0.789
2011 Langley RR, Fidler IJ. The seed and soil hypothesis revisited--the role of tumor-stroma interactions in metastasis to different organs. International Journal of Cancer. 128: 2527-35. PMID 21365651 DOI: 10.1002/Ijc.26031  0.408
2011 Weihua Z, Lin Q, Ramoth AJ, Fan D, Fidler IJ. Formation of solid tumors by a single multinucleated cancer cell. Cancer. 117: 4092-9. PMID 21365635 DOI: 10.1002/Cncr.26021  0.776
2011 Kim SW, Kim JS, Papadopoulos J, Choi HJ, He J, Maya M, Langley RR, Fan D, Fidler IJ, Kim SJ. Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse. International Immunopharmacology. 11: 862-72. PMID 21251905 DOI: 10.1016/J.Intimp.2011.01.004  0.428
2011 Fidler IJ. The role of the organ microenvironment in brain metastasis. Seminars in Cancer Biology. 21: 107-12. PMID 21167939 DOI: 10.1016/J.Semcancer.2010.12.009  0.482
2011 Fidler IJ. The biology of cancer metastasis. Seminars in Cancer Biology. 21: 71. PMID 21145967 DOI: 10.1016/J.Semcancer.2010.12.004  0.338
2011 Kim SJ, Kim JS, Kim SW, Brantley EC, Yun SJ, He J, Marva MK, Zhang F, Wu Q, Lehembre F, Regenass U, Fidler IJ. Abstract 601: Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer Cancer Research. 71: 601-601. DOI: 10.1158/1538-7445.Am2011-601  0.482
2011 Yokoi K, Godin B, Alexander JF, Hu T, Liu X, Fidler I, Ferrari M. Abstract 379: Target delivery of multistage nanovectors to tumor-associated macrophages and endothelial cells in orthotopic model of human pancreatic cancer Cancer Research. 71: 379-379. DOI: 10.1158/1538-7445.Am2011-379  0.488
2011 Yokoi K, Xuewu L, Alexander J, Fidler I, Mauro F, Biana G. P4-17-10: Insights into Mechanisms Involved in the Accumulation of Nanovectors within the Breast Cancer Brain Metastasis. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-17-10  0.387
2010 Brantley EC, Guo L, Zhang C, Lin Q, Yokoi K, Langley RR, Kruzel E, Maya M, Kim SW, Kim SJ, Fan D, Fidler IJ. Nitric oxide-mediated tumoricidal activity of murine microglial cells. Translational Oncology. 3: 380-8. PMID 21151477 DOI: 10.1593/Tlo.10208  0.772
2010 Lin Q, Balasubramanian K, Fan D, Kim SJ, Guo L, Wang H, Bar-Eli M, Aldape KD, Fidler IJ. Reactive astrocytes protect melanoma cells from chemotherapy by sequestering intracellular calcium through gap junction communication channels. Neoplasia (New York, N.Y.). 12: 748-54. PMID 20824051 DOI: 10.1593/Neo.10602  0.767
2010 Ellis LM, Fidler IJ. Finding the tumor copycat. Therapy fails, patients don't. Nature Medicine. 16: 974-5. PMID 20823880 DOI: 10.1038/Nm0910-974  0.391
2010 Fidler IJ, Balasubramanian K, Lin Q, Kim SW, Kim SJ. The brain microenvironment and cancer metastasis. Molecules and Cells. 30: 93-8. PMID 20799011 DOI: 10.1007/S10059-010-0133-9  0.765
2010 Talmadge JE, Fidler IJ. AACR centennial series: the biology of cancer metastasis: historical perspective. Cancer Research. 70: 5649-69. PMID 20610625 DOI: 10.1158/0008-5472.Can-10-1040  0.403
2010 Kuo HP, Lee DF, Chen CT, Liu M, Chou CK, Lee HJ, Du Y, Xie X, Wei Y, Xia W, Weihua Z, Yang JY, Yen CJ, Huang TH, Tan M, ... ... Fidler IJ, et al. ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway. Science Signaling. 3: ra9. PMID 20145209 DOI: 10.1126/Scisignal.2000590  0.381
2010 Rebhun RB, Cheng H, Gershenwald JE, Fan D, Fidler IJ, Langley RR. Constitutive expression of the alpha4 integrin correlates with tumorigenicity and lymph node metastasis of the B16 murine melanoma. Neoplasia (New York, N.Y.). 12: 173-82. PMID 20126475 DOI: 10.1593/Neo.91604  0.683
2010 Kim SJ, Kim J, Park ES, Lee J, Lin Q, Langley RR, Maya M, He J, Kim SW, Weihua Z, Balasubramanian K, Fan D, Mills GB, Hung M, Fidler IJ. Abstract 3428: Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy Cancer Research. 70: 3428-3428. DOI: 10.1158/1538-7445.Am10-3428  0.498
2009 Langley RR, Fan D, Guo L, Zhang C, Lin Q, Brantley EC, McCarty JH, Fidler IJ. Generation of an immortalized astrocyte cell line from H-2Kb-tsA58 mice to study the role of astrocytes in brain metastasis. International Journal of Oncology. 35: 665-72. PMID 19724901 DOI: 10.3892/Ijo_00000378  0.758
2009 Kim SJ, Kim JS, Papadopoulos J, Wook Kim S, Maya M, Zhang F, He J, Fan D, Langley R, Fidler IJ. Circulating monocytes expressing CD31: implications for acute and chronic angiogenesis. The American Journal of Pathology. 174: 1972-80. PMID 19349357 DOI: 10.2353/Ajpath.2009.080819  0.389
2009 Zhang C, Zhang F, Tsan R, Fidler IJ. Transforming growth factor-beta2 is a molecular determinant for site-specific melanoma metastasis in the brain. Cancer Research. 69: 828-35. PMID 19141644 DOI: 10.1158/0008-5472.Can-08-2588  0.387
2009 Mathew P, Pisters LL, Wood CG, Papadopoulos JN, Williams DL, Thall PF, Wen S, Horne E, Oborn CJ, Langley R, Fidler IJ, Pettaway CA. Neoadjuvant platelet derived growth factor receptor inhibitor therapy combined with docetaxel and androgen ablation for high risk localized prostate cancer. The Journal of Urology. 181: 81-7; discussion 87. PMID 19012911 DOI: 10.1016/J.Juro.2008.09.006  0.304
2008 Mathew P, Thall PF, Wen S, Bucana C, Jones D, Horne E, Oh WK, Morris MJ, Lee YC, Logothetis CJ, Lin SH, Fidler IJ. Dynamic change in phosphorylated platelet-derived growth factor receptor in peripheral blood leukocytes following docetaxel therapy predicts progression-free and overall survival in prostate cancer British Journal of Cancer. 99: 1426-1432. PMID 18841158 DOI: 10.1038/Sj.Bjc.6604706  0.318
2008 Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. The Journal of Biological Chemistry. 283: 29447-60. PMID 18718906 DOI: 10.1074/Jbc.M804595200  0.349
2008 Sasaki T, Nakamura T, Rebhun RB, Cheng H, Hale KS, Tsan RZ, Fidler IJ, Langley RR. Modification of the primary tumor microenvironment by transforming growth factor alpha-epidermal growth factor receptor signaling promotes metastasis in an orthotopic colon cancer model. The American Journal of Pathology. 173: 205-16. PMID 18583324 DOI: 10.2353/Ajpath.2008.071147  0.702
2008 Kuwai T, Nakamura T, Sasaki T, Kim SJ, Fan D, Villares GJ, Zigler M, Wang H, Bar-Eli M, Kerbel RS, Fidler IJ. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors. Neoplasia (New York, N.Y.). 10: 489-500. PMID 18472966 DOI: 10.1593/Neo.08200  0.456
2008 Weihua Z, Tsan R, Huang WC, Wu Q, Chiu CH, Fidler IJ, Hung MC. Survival of cancer cells is maintained by EGFR independent of its kinase activity. Cancer Cell. 13: 385-93. PMID 18455122 DOI: 10.1016/J.Ccr.2008.03.015  0.393
2008 Kuwai T, Nakamura T, Sasaki T, Kitadai Y, Kim JS, Langley RR, Fan D, Wang X, Do KA, Kim SJ, Fidler IJ. Targeting the EGFR, VEGFR, and PDGFR on colon cancer cells and stromal cells is required for therapy. Clinical & Experimental Metastasis. 25: 477-89. PMID 18324358 DOI: 10.1007/S10585-008-9153-7  0.517
2008 Rebhun RB, Lazar AJ, Fidler IJ, Gershenwald JE. Impact of sentinel lymphadenectomy on survival in a murine model of melanoma. Clinical & Experimental Metastasis. 25: 191-9. PMID 18264782 DOI: 10.1007/S10585-008-9141-Y  0.643
2008 Kuwai T, Nakamura T, Kim SJ, Sasaki T, Kitadai Y, Langley RR, Fan D, Hamilton SR, Fidler IJ. Intratumoral heterogeneity for expression of tyrosine kinase growth factor receptors in human colon cancer surgical specimens and orthotopic tumors. The American Journal of Pathology. 172: 358-66. PMID 18202197 DOI: 10.2353/Ajpath.2008.070625  0.465
2008 Kitadai Y, Kodama M, Tanaka M, Sasaki T, Kuwai T, Nakamura T, Fidler I. Inhibition of reactive stroma by platelet derived growth factor receptor (PDGF-R) tyrosine kinase inhibitor reduces growth and lymph node metastasis of human colon carcinoma European Journal of Cancer Supplements. 6: 68. DOI: 10.1016/S1359-6349(08)71436-8  0.33
2008 Yazici S, Busby E, Kim SJ, Fidler IJ. IN VIVO IMAGING OF LUCIFERASE-LABELED HUMAN PROSTATE CANCER CELLS, PC-3MM2, IN ORTHOTOPIC NUDE MOUSE MODELS Journal of Urology. 179: 425-425. DOI: 10.1016/S0022-5347(08)61246-X  0.335
2007 Sasaki T, Kitadai Y, Nakamura T, Kim JS, Tsan RZ, Kuwai T, Langley RR, Fan D, Kim SJ, Fidler IJ. Inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation on tumor-associated endothelial cells leads to treatment of orthotopic human colon cancer in nude mice. Neoplasia (New York, N.Y.). 9: 1066-77. PMID 18084614 DOI: 10.1593/Neo.07667  0.482
2007 Nakamura T, Kuwai T, Kim JS, Fan D, Kim SJ, Fidler IJ. Stromal metalloproteinase-9 is essential to angiogenesis and progressive growth of orthotopic human pancreatic cancer in parabiont nude mice. Neoplasia (New York, N.Y.). 9: 979-86. PMID 18030366 DOI: 10.1593/Neo.07742  0.375
2007 Wu W, O'Reilly MS, Langley RR, Tsan RZ, Baker CH, Bekele N, Tang XM, Onn A, Fidler IJ, Herbst RS. Expression of epidermal growth factor (EGF)/transforming growth factor-alpha by human lung cancer cells determines their response to EGF receptor tyrosine kinase inhibition in the lungs of mice. Molecular Cancer Therapeutics. 6: 2652-63. PMID 17913856 DOI: 10.1158/1535-7163.Mct-06-0759  0.47
2007 Mathew P, Thall PF, Bucana CD, Oh WK, Morris MJ, Jones DM, Johnson MM, Wen S, Pagliaro LC, Tannir NM, Tu SM, Meluch AA, Smith L, Cohen L, Kim SJ, ... ... Fidler IJ, et al. Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 5816-24. PMID 17908974 DOI: 10.1158/1078-0432.Ccr-07-1269  0.318
2007 Nakamura T, Kuwai T, Kitadai Y, Sasaki T, Fan D, Coombes KR, Kim SJ, Fidler IJ. Zonal heterogeneity for gene expression in human pancreatic carcinoma. Cancer Research. 67: 7597-604. PMID 17699763 DOI: 10.1158/0008-5472.Can-07-0874  0.399
2007 Langley RR, Fidler IJ. Tumor cell-organ microenvironment interactions in the pathogenesis of cancer metastasis. Endocrine Reviews. 28: 297-321. PMID 17409287 DOI: 10.1210/Er.2006-0027  0.494
2007 Talmadge JE, Singh RK, Fidler IJ, Raz A. Murine models to evaluate novel and conventional therapeutic strategies for cancer. The American Journal of Pathology. 170: 793-804. PMID 17322365 DOI: 10.2353/Ajpath.2007.060929  0.374
2007 Wu W, Onn A, Isobe T, Itasaka S, Langley RR, Shitani T, Shibuya K, Komaki R, Ryan AJ, Fidler IJ, Herbst RS, O'Reilly MS. Targeted therapy of orthotopic human lung cancer by combined vascular endothelial growth factor and epidermal growth factor receptor signaling blockade. Molecular Cancer Therapeutics. 6: 471-83. PMID 17308046 DOI: 10.1158/1535-7163.Mct-06-0416  0.411
2007 Nakamura T, Fidler IJ, Coombes KR. Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment. Cancer Research. 67: 139-48. PMID 17210693 DOI: 10.1158/0008-5472.Can-06-2563  0.399
2007 Fidler IJ, Kim SJ, Langley RR. The role of the organ microenvironment in the biology and therapy of cancer metastasis. Journal of Cellular Biochemistry. 101: 927-36. PMID 17177290 DOI: 10.1002/Jcb.21148  0.482
2006 Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Fidler IJ. Targeting the expression of platelet-derived growth factor receptor by reactive stroma inhibits growth and metastasis of human colon carcinoma. The American Journal of Pathology. 169: 2054-65. PMID 17148668 DOI: 10.2353/Ajpath.2006.060653  0.511
2006 Fidler IJ. Models for spontaneous metastasis. Cancer Research. 66: 9787. PMID 17018641 DOI: 10.1158/0008-5472.Can-06-2396  0.342
2006 Busby JE, Kim SJ, Yazici S, Nakamura T, Kim JS, He J, Maya M, Wang X, Do KA, Fan D, Fidler IJ. Therapy of multidrug resistant human prostate tumors in the prostate of nude mice by simultaneous targeting of the epidermal growth factor receptor and vascular endothelial growth factor receptor on tumor-associated endothelial cells. The Prostate. 66: 1788-98. PMID 17013882 DOI: 10.1002/Pros.20519  0.429
2006 Kitadai Y, Sasaki T, Kuwai T, Nakamura T, Bucana CD, Hamilton SR, Fidler IJ. Expression of activated platelet-derived growth factor receptor in stromal cells of human colon carcinomas is associated with metastatic potential. International Journal of Cancer. 119: 2567-74. PMID 16988946 DOI: 10.1002/Ijc.22229  0.466
2006 Rebhun RB, Langley RR, Yokoi K, Fan D, Gershenwald JE, Fidler IJ. Targeting receptor tyrosine kinase on lymphatic endothelial cells for the therapy of colon cancer lymph node metastasis. Neoplasia (New York, N.Y.). 8: 747-57. PMID 16984732 DOI: 10.1593/Neo.06322  0.7
2006 Zhang W, Tsan R, Nam DH, Lu W, Fidler IJ. Loss of adhesion in the circulation converts amelanotic metastatic melanoma cells to melanotic by inhibition of AKT. Neoplasia (New York, N.Y.). 8: 543-50. PMID 16867216 DOI: 10.1593/Neo.05655  0.408
2006 Baker CH, Pino MS, Fidler IJ. Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells in human renal cell carcinoma is a primary target for therapy by tyrosine kinase inhibitors. Neoplasia (New York, N.Y.). 8: 470-6. PMID 16820093 DOI: 10.1593/Neo.06172  0.465
2006 Baker CH, Trevino JG, Summy JM, Zhang F, Caron A, Nesbit M, Gallick GE, Fidler IJ. Inhibition of PDGFR phosphorylation and Src and Akt activity by GN963 leads to therapy of human pancreatic cancer growing orthotopically in nude mice. International Journal of Oncology. 29: 125-38. PMID 16773192 DOI: 10.3892/Ijo.29.1.125  0.48
2006 Kim SJ, Uehara H, Yazici S, Busby JE, Nakamura T, He J, Maya M, Logothetis C, Mathew P, Wang X, Do KA, Fan D, Fidler IJ. Targeting platelet-derived growth factor receptor on endothelial cells of multidrug-resistant prostate cancer. Journal of the National Cancer Institute. 98: 783-93. PMID 16757703 DOI: 10.1093/Jnci/Djj211  0.459
2006 Mathew P, Thall PF, Johnson MM, Oh WK, Meluch AA, Morris MJ, Troncoso P, Bucana CD, Fidler IJ, Logothetis CJ. Preliminary results of a randomized placebo-controlled double-blind trial of weekly docetaxel combined with imatinib in men with metastatic androgen-independent prostate cancer (AIPC) and bone metastases (BM) Journal of Clinical Oncology. 24: 4562-4562. DOI: 10.1200/Jco.2006.24.18_Suppl.4562  0.322
2006 Mathew P, Thall P, Wen S, Horne E, Johnson M, Oh W, Morris M, Logothetis C, Fidler I, Bucana C. 79 POSTER Correlative results of in-vivo monitoring of platelet-derived growth factor receptor (PDGFR) activation status in a randomized placebocontrolled trial of docetaxel +/− imatinib in castration-resistant prostate cancer (CRPC) and bone metastases (BM) European Journal of Cancer Supplements. 4: 28. DOI: 10.1016/S1359-6349(06)70085-4  0.313
2006 Busby JE, Kim S, Yazici MS, Fan D, Fidler IJ. 792: Therapy of Multidrug Resistant Prostate Cancer by Targeting the Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor On Tumor-Associated Endothelial Cells Journal of Urology. 175: 256-256. DOI: 10.1016/S0022-5347(18)33028-3  0.4
2005 Weihua Z, Tsan R, Schroit AJ, Fidler IJ. Apoptotic cells initiate endothelial cell sprouting via electrostatic signaling. Cancer Research. 65: 11529-35. PMID 16357162 DOI: 10.1158/0008-5472.Can-05-2718  0.384
2005 Cheng H, Langley RR, Wu Q, Wu W, Feng J, Tsan R, Fan D, Fidler IJ. Construction of a novel constitutively active chimeric EGFR to identify new targets for therapy. Neoplasia (New York, N.Y.). 7: 1065-72. PMID 16354589 DOI: 10.1593/Neo.05553  0.387
2005 Nilsson MB, Langley RR, Fidler IJ. Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine. Cancer Research. 65: 10794-800. PMID 16322225 DOI: 10.1158/0008-5472.Can-05-0623  0.669
2005 Yokoi K, Sasaki T, Bucana CD, Fan D, Baker CH, Kitadai Y, Kuwai T, Abbruzzese JL, Fidler IJ. Simultaneous inhibition of EGFR, VEGFR, and platelet-derived growth factor receptor signaling combined with gemcitabine produces therapy of human pancreatic carcinoma and prolongs survival in an orthotopic nude mouse model. Cancer Research. 65: 10371-80. PMID 16288027 DOI: 10.1158/0008-5472.Can-05-1698  0.488
2005 Yokoi K, Shih LCN, Kobayashi R, Koomen J, Hawke D, Li D, Hamilton SR, Abbruzzese JL, Coombes KR, Fidler IJ. Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer International Journal of Oncology. 27: 1361-1369. PMID 16211233 DOI: 10.3892/Ijo.27.5.1361  0.387
2005 Yokoi K, Kim SJ, Thaker P, Yazici S, Nam DH, He J, Sasaki T, Chiao PJ, Sclabas GM, Abbruzzese JL, Hamilton SR, Fidler IJ. Induction of apoptosis in tumor-associated endothelial cells and therapy of orthotopic human pancreatic carcinoma in nude mice. Neoplasia (New York, N.Y.). 7: 696-704. PMID 16026649 DOI: 10.1593/Neo.05193  0.502
2005 Thaker PH, Yazici S, Nilsson MB, Yokoi K, Tsan RZ, He J, Kim SJ, Fidler IJ, Sood AK. Antivascular therapy for orthotopic human ovarian carcinoma through blockade of the vascular endothelial growth factor and epidermal growth factor receptors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 4923-33. PMID 16000591 DOI: 10.1158/1078-0432.Ccr-04-2060  0.649
2005 Yazici S, Kim SJ, Busby JE, He J, Thaker P, Yokoi K, Fan D, Fidler IJ. Dual inhibition of the epidermal growth factor and vascular endothelial growth factor phosphorylation for antivascular therapy of human prostate cancer in the prostate of nude mice. The Prostate. 65: 203-15. PMID 15948138 DOI: 10.1002/Pros.20283  0.381
2005 Younes MN, Yigitbasi OG, Park YW, Kim SJ, Jasser SA, Hawthorne VS, Yazici YD, Mandal M, Bekele BN, Bucana CD, Fidler IJ, Myers JN. Antivascular therapy of human follicular thyroid cancer experimental bone metastasis by blockade of epidermal growth factor receptor and vascular growth factor receptor phosphorylation. Cancer Research. 65: 4716-27. PMID 15930290 DOI: 10.1158/0008-5472.Can-04-4196  0.419
2005 Yokoi K, Thaker PH, Yazici S, Rebhun RR, Nam DH, He J, Kim SJ, Abbruzzese JL, Hamilton SR, Fidler IJ. Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model. Cancer Research. 65: 3716-25. PMID 15867367 DOI: 10.1158/0008-5472.Can-04-3700  0.512
2005 Kim SJ, Uehara H, Yazici S, He J, Langley RR, Mathew P, Fan D, Fidler IJ. Modulation of bone microenvironment with zoledronate enhances the therapeutic effects of STI571 and paclitaxel against experimental bone metastasis of human prostate cancer. Cancer Research. 65: 3707-15. PMID 15867366 DOI: 10.1158/0008-5472.Can-04-3601  0.435
2005 Uehara H, Troncoso P, Johnston D, Bucana CD, Dinney C, Dong Z, Fidler IJ, Pettaway CA. Expression of interleukin-8 gene in radical prostatectomy specimens is associated with advanced pathologic stage. The Prostate. 64: 40-9. PMID 15651067 DOI: 10.1002/Pros.20223  0.365
2005 Cheng H, Cenciarelli C, Nelkin G, Tsan R, Fan D, Cheng-Mayer C, Fidler IJ. Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth. Molecular and Cellular Biology. 25: 44-59. PMID 15601829 DOI: 10.1128/Mcb.25.1.44-59.2005  0.41
2005 Kim SJ, Sertac Yazici M, Busby E, He J, Fan D, Fidler IJ. 568: Treatment of Human Prostate Cancer Cells Growing in the Bone of Nude Mice with AEE788, Inhibitor of Epidermal Growth Factor and Vascular Growth Factor Receptor, and Paclitaxel Journal of Urology. 173: 155-155. DOI: 10.1016/S0022-5347(18)34808-0  0.385
2005 Kim SJ, Yazici MS, Uehara H, Busby E, He J, Fan D, Fidler IJ. 393: Bypass of Drug-Resistance by Antivascular Therapy with Protein Tyrosine Kinase Inhibitor, STI571, in Human Prostate Cancer Bone Metastasis Model of Nude Mice Journal of Urology. 173: 107-108. DOI: 10.1016/S0022-5347(18)34646-9  0.324
2004 Yokoi K, Raber MN, Shih LN, Li D, Hamilton SR, Fidler IJ, Abbruzzese JL. Serum Amyloid A (SAA) in Patients with Pancreatic Carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 9649. PMID 28016244 DOI: 10.1200/Jco.2004.22.90140.9649  0.356
2004 Onn A, Isobe T, Wu W, Itasaka S, Shintani T, Shibuya K, Kenji Y, O'reilly MS, Fidler IJ, Herbst RS. Epidermal growth factor receptor tyrosine kinase inhibitor does not improve paclitaxel effect in an orthotopic mouse model of lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 8613-9. PMID 15623645 DOI: 10.1158/1078-0432.Ccr-04-1241  0.407
2004 Yigitbasi OG, Younes MN, Doan D, Jasser SA, Schiff BA, Bucana CD, Bekele BN, Fidler IJ, Myers JN. Tumor cell and endothelial cell therapy of oral cancer by dual tyrosine kinase receptor blockade. Cancer Research. 64: 7977-84. PMID 15520205 DOI: 10.1158/0008-5472.Can-04-1477  0.493
2004 Fidler IJ, Ellis LM. Neoplastic angiogenesis--not all blood vessels are created equal. The New England Journal of Medicine. 351: 215-6. PMID 15254281 DOI: 10.1056/Nejmp048080  0.408
2004 Kim SJ, Uehara H, Yazici S, Langley RR, He J, Tsan R, Fan D, Killion JJ, Fidler IJ. Simultaneous blockade of platelet-derived growth factor-receptor and epidermal growth factor-receptor signaling and systemic administration of paclitaxel as therapy for human prostate cancer metastasis in bone of nude mice. Cancer Research. 64: 4201-8. PMID 15205332 DOI: 10.1158/0008-5472.Can-03-3763  0.434
2004 Mathew P, Fidler IJ, Logothetis CJ. Combination docetaxel and platelet-derived growth factor receptor inhibition with imatinib mesylate in prostate cancer. Seminars in Oncology. 31: 24-9. PMID 15176001 DOI: 10.1053/J.Seminoncol.2004.03.037  0.351
2004 Langley RR, Fan D, Tsan RZ, Rebhun R, He J, Kim SJ, Fidler IJ. Activation of the platelet-derived growth factor-receptor enhances survival of murine bone endothelial cells. Cancer Research. 64: 3727-30. PMID 15172974 DOI: 10.1158/0008-5472.Can-03-3863  0.664
2004 Yokoi K, Fidler IJ. Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2299-306. PMID 15073105 DOI: 10.1158/1078-0432.Ccr-03-0488  0.347
2004 Apte SM, Bucana CD, Killion JJ, Gershenson DM, Fidler IJ. Expression of platelet-derived growth factor and activated receptor in clinical specimens of epithelial ovarian cancer and ovarian carcinoma cell lines. Gynecologic Oncology. 93: 78-86. PMID 15047217 DOI: 10.1016/J.Ygyno.2003.12.041  0.469
2004 Apte SM, Fan D, Killion JJ, Fidler IJ. Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 897-908. PMID 14871965 DOI: 10.1158/1078-0432.Ccr-1151-3  0.396
2004 Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS. Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 136-43. PMID 14734462 DOI: 10.1158/1078-0432.Ccr-0373-3  0.352
2003 McCarty MF, Bielenberg DR, Nilsson MB, Gershenwald JE, Barnhill RL, Ahearne P, Bucana CD, Fidler IJ. Epidermal hyperplasia overlying human melanoma correlates with tumour depth and angiogenesis. Melanoma Research. 13: 379-87. PMID 12883364 DOI: 10.1097/00008390-200308000-00007  0.802
2003 Langley RR, Ramirez KM, Tsan RZ, Van Arsdall M, Nilsson MB, Fidler IJ. Tissue-specific microvascular endothelial cell lines from H-2K(b)-tsA58 mice for studies of angiogenesis and metastasis. Cancer Research. 63: 2971-6. PMID 12782605  0.676
2003 Weber KL, Doucet M, Price JE, Baker C, Kim SJ, Fidler IJ. Blockade of epidermal growth factor receptor signaling leads to inhibition of renal cell carcinoma growth in the bone of nude mice. Cancer Research. 63: 2940-7. PMID 12782601  0.384
2003 Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nature Reviews. Cancer. 3: 453-8. PMID 12778135 DOI: 10.1038/Nrc1098  0.404
2003 Fidler IJ, Kripke ML. Genomic analysis of primary tumors does not address the prevalence of metastatic cells in the population. Nature Genetics. 34: 23; author reply 25. PMID 12721548 DOI: 10.1038/Ng0503-23A  0.369
2003 Ozawa S, Lu W, Bucana CD, Kanayama HO, Shinohara H, Fidler IJ, Dong Z. Regression of primary murine colon cancer and occult liver metastasis by intralesional injection of lyophilized preparation of insect cells producing murine interferon-beta. International Journal of Oncology. 22: 977-84. PMID 12684662 DOI: 10.3892/Ijo.22.5.977  0.45
2003 Uehara H, Kim SJ, Karashima T, Shepherd DL, Fan D, Tsan R, Killion JJ, Logothetis C, Mathew P, Fidler IJ. Effects of blocking platelet-derived growth factor-receptor signaling in a mouse model of experimental prostate cancer bone metastases. Journal of the National Cancer Institute. 95: 458-70. PMID 12644539 DOI: 10.1093/Jnci/95.6.458  0.389
2003 Kim SJ, Uehara H, Karashima T, Shepherd DL, Killion JJ, Fidler IJ. Blockade of epidermal growth factor receptor signaling in tumor cells and tumor-associated endothelial cells for therapy of androgen-independent human prostate cancer growing in the bone of nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1200-10. PMID 12631626  0.327
2003 Fidler IJ, Yoneda J, Herrera C, Wood J, Xu L. Specific keynote: molecular determinants of angiogenesis in ovarian cancer. Gynecologic Oncology. 88: S29-36; discussion S. PMID 12586082 DOI: 10.1006/Gyno.2002.6680  0.311
2003 Onn A, Fidler IJ. Metastatic potential of human neoplasms. In Vivo (Athens, Greece). 16: 423-9. PMID 12494885  0.375
2003 Takahashi Y, Kitadai Y, Ellis LM, Bucana CD, Fidler IJ, Mai M. Multiparametric in situ mRNA hybridization analysis of gastric biopsies predicts lymph node metastasis in patients with gastric carcinoma. Japanese Journal of Cancer Research : Gann. 93: 1258-65. PMID 12460468 DOI: 10.1111/J.1349-7006.2002.Tb01232.X  0.359
2003 Kedar D, Baker CH, Killion JJ, Dinney CP, Fidler IJ. Blockade of the epidermal growth factor receptor signaling inhibits angiogenesis leading to regression of human renal cell carcinoma growing orthotopically in nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3592-600. PMID 12429651  0.342
2003 Fidler IJ. Critical determinants of metastasis. Seminars in Cancer Biology. 12: 89-96. PMID 12027580 DOI: 10.1006/Scbi.2001.0416  0.472
2003 Onn A, Correa AM, Gilcrease M, Massarelli E, Bucana CD, Ki Hong W, Fidler IJ, Putnam JB, Herbst RS. P-484 Synchronous overexpression of epidermal growth factor receptor and HER2-NEU is a predictor of poor outcome in patients with stage I non-small cell lung cancer Lung Cancer. 41: S213. DOI: 10.1016/S0169-5002(03)92451-2  0.34
2003 Kohn EC, Fidler IJ, Fishman D, Jaffe R, Liotta LA, Van Trappen P, Mills GB, Trope C. Discussion: Metastasis and Angiogenesis in Epithelial Ovarian Cancer Gynecologic Oncology. 88: S37-S42. DOI: 10.1006/Gyno.2002.6681  0.355
2002 McCarty MF, Bielenberg D, Donawho C, Bucana CD, Fidler IJ. Evidence for the causal role of endogenous interferon-alpha/beta in the regulation of angiogenesis, tumorigenicity, and metastasis of cutaneous neoplasms. Clinical & Experimental Metastasis. 19: 609-15. PMID 12498390 DOI: 10.1023/A:1020923326441  0.728
2002 Fidler IJ. The organ microenvironment and cancer metastasis Differentiation. 70: 498-505. PMID 12492492 DOI: 10.1046/J.1432-0436.2002.700904.X  0.472
2002 Fan D, Liaw A, Denkins YM, Collins JH, Van Arsdall M, Chang JL, Chakrabarty S, Nguyen D, Kruzel E, Fidler IJ. Type-1 transforming growth factor-beta differentially modulates tumoricidal activity of murine peritoneal macrophages against metastatic variants of the B16 murine melanoma. Journal of Experimental Therapeutics & Oncology. 2: 286-97. PMID 12416032 DOI: 10.1046/J.1359-4117.2002.01053.X  0.317
2002 Baker CH, Kedar D, McCarty MF, Tsan R, Weber KL, Bucana CD, Fidler IJ. Blockade of epidermal growth factor receptor signaling on tumor cells and tumor-associated endothelial cells for therapy of human carcinomas. The American Journal of Pathology. 161: 929-38. PMID 12213721 DOI: 10.1016/S0002-9440(10)64253-8  0.767
2002 Huang S, Van Arsdall M, Tedjarati S, McCarty M, Wu W, Langley R, Fidler IJ. Contributions of stromal metalloproteinase-9 to angiogenesis and growth of human ovarian carcinoma in mice. Journal of the National Cancer Institute. 94: 1134-42. PMID 12165638 DOI: 10.1093/Jnci/94.15.1134  0.736
2002 Myers JN, Holsinger FC, Bekele BN, Li E, Jasser SA, Killion JJ, Fidler IJ. Targeted molecular therapy for oral cancer with epidermal growth factor receptor blockade: a preliminary report. Archives of Otolaryngology--Head & Neck Surgery. 128: 875-9. PMID 12162763 DOI: 10.1001/Archotol.128.8.875  0.37
2002 Lu W, Dong Z, Donawho C, Fidler IJ. Specific immunotherapy against occult cancer metastases. International Journal of Cancer. 100: 480-5. PMID 12115534 DOI: 10.1002/Ijc.10494  0.391
2002 McCarty MF, Baker CH, Bucana CD, Fidler IJ. Quantitative and qualitative in vivo angiogenesis assay. International Journal of Oncology. 21: 5-10. PMID 12063542 DOI: 10.3892/Ijo.21.1.5  0.727
2002 Gershenwald JE, Fidler IJ. Cancer. Targeting lymphatic metastasis. Science (New York, N.Y.). 296: 1811-2. PMID 12052939 DOI: 10.1126/Science.10731318  0.413
2002 Huang S, Bucana CD, Van Arsdall M, Fidler IJ. Stat1 negatively regulates angiogenesis, tumorigenicity and metastasis of tumor cells. Oncogene. 21: 2504-12. PMID 11971185 DOI: 10.1038/Sj.Onc.1205341  0.482
2002 Baker CH, Solorzano CC, Fidler IJ. Blockade of vascular endothelial growth factor receptor and epidermal growth factor receptor signaling for therapy of metastatic human pancreatic cancer. Cancer Research. 62: 1996-2003. PMID 11929816  0.337
2002 Fidler IJ, Yano S, Zhang RD, Fujimaki T, Bucana CD. The seed and soil hypothesis: vascularisation and brain metastases. The Lancet. Oncology. 3: 53-7. PMID 11905606 DOI: 10.1016/S1470-2045(01)00622-2  0.375
2002 Kuniyasu H, Yasui W, Pettaway CA, Yano S, Oue N, Tahara E, Fidler IJ. Interferon-alpha prevents selection of doxorubicin-resistant undifferentiated-androgen-insensitive metastatic human prostate cancer cells. The Prostate. 49: 19-29. PMID 11550207 DOI: 10.1002/Pros.1114  0.378
2002 Herrera CA, Xu L, Bucana CD, Silva EVG, Hess KR, Gershenson DM, Fidler IJ. Expression of metastasis-related genes in human epithelial ovarian tumors International Journal of Oncology. 20: 5-13. DOI: 10.3892/Ijo.20.1.5  0.325
2001 Solorzano CC, Baker CH, Bruns CJ, Killion JJ, Ellis LM, Wood J, Fidler IJ. Inhibition of growth and metastasis of human pancreatic cancer growing in nude mice by PTK 787/ZK222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. Cancer Biotherapy & Radiopharmaceuticals. 16: 359-70. PMID 11776753 DOI: 10.1089/108497801753354267  0.475
2001 Baker CH, Solorzano CC, Fidler IJ. Angiogenesis and cancer metastasis: antiangiogenic therapy of human pancreatic adenocarcinoma. International Journal of Clinical Oncology. 6: 59-65. PMID 11706751 DOI: 10.1007/Pl00012085  0.355
2001 Kuniyasu H, Abbruzzese JL, Cleary KR, Fidler IJ. Induction of ductal and stromal hyperplasia by basic fibroblast growth factor produced by human pancreatic carcinoma. International Journal of Oncology. 19: 681-5. PMID 11562741 DOI: 10.3892/Ijo.19.4.681  0.422
2001 Huang S, Pettaway CA, Uehara H, Bucana CD, Fidler IJ. Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis. Oncogene. 20: 4188-97. PMID 11464285 DOI: 10.1038/Sj.Onc.1204535  0.408
2001 Ozawa S, Shinohara H, Kanayama HO, Bruns CJ, Bucana CD, Ellis LM, Davis DW, Fidler IJ. Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha. Neoplasia (New York, N.Y.). 3: 154-64. PMID 11420751 DOI: 10.1038/Sj.Neo.7900128  0.408
2001 Kim SJ, Uehara H, Karashima T, Mccarty M, Shih N, Fidler IJ. Expression of interleukin-8 correlates with angiogenesis, tumorigenicity, and metastasis of human prostate cancer cells implanted orthotopically in nude mice. Neoplasia (New York, N.Y.). 3: 33-42. PMID 11326314 DOI: 10.1038/Sj.Neo.7900124  0.735
2001 Berry KK, Varney ML, Dave BJ, Bucana CD, Fidler IJ, Singh RK. Expression of interleukin-8 in human metastatic endometrial carcinoma cells and its regulation by inflammatory cytokines. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 11: 54-60. PMID 11285034 DOI: 10.1046/J.1525-1438.2001.011001054.X  0.364
2001 Slaton JW, Inoue K, Perrotte P, El-Naggar AK, Swanson DA, Fidler IJ, Dinney CP. Expression levels of genes that regulate metastasis and angiogenesis correlate with advanced pathological stage of renal cell carcinoma. The American Journal of Pathology. 158: 735-43. PMID 11159211 DOI: 10.1016/S0002-9440(10)64016-3  0.392
2001 Xu L, Fidler IJ. Interleukin 8: an autocrine growth factor for human ovarian cancer. Oncology Research. 12: 97-106. PMID 11132928 DOI: 10.3727/096504001108747567  0.329
2001 Yano S, Shinohara H, Herbst RS, Kuniyasu H, Bucana CD, Ellis LM, Fidler IJ. Production of experimental malignant pleural effusions is dependent on invasion of the pleura and expression of vascular endothelial growth factor/vascular permeability factor by human lung cancer cells. The American Journal of Pathology. 157: 1893-903. PMID 11106562 DOI: 10.1016/S0002-9440(10)64828-6  0.442
2001 Andreeff M, Studeny M, Zoltick P, Zompetta C, Wilson J, Fidler IJ, Marini F. Mesenchymal stem cells (MSC) as carriers of biologically active molecules in cancer and leukemia therapy European Journal of Cancer. 37: S81. DOI: 10.1016/S0959-8049(01)80445-7  0.322
2000 Kanayama H, Yano S, Kim SJ, Ozawa S, Ellis LM, Fidler IJ. Expression of vascular endothelial growth factor by human renal cancer cells enhances angiogenesis of primary tumors and production of ascites but not metastasis to the lungs in nude mice. Clinical & Experimental Metastasis. 17: 831-40. PMID 11089881 DOI: 10.1023/A:1006792007063  0.464
2000 Kuniyasu H, Yasui W, Shinohara H, Yano S, Ellis LM, Wilson MR, Bucana CD, Rikita T, Tahara E, Fidler IJ. Induction of angiogenesis by hyperplastic colonic mucosa adjacent to colon cancer. The American Journal of Pathology. 157: 1523-35. PMID 11073812 DOI: 10.1016/S0002-9440(10)64790-6  0.457
2000 Shinohara H, Fan D, Ozawa S, Yano S, Van Arsdell M, Viner JL, Beers R, Pastan I, Fidler IJ. Site-specific expression of transferrin receptor by human colon cancer cells directly correlates with eradication by antitransferrin recombinant immunotoxin. International Journal of Oncology. 17: 643-51. PMID 10995873 DOI: 10.3892/Ijo.17.4.643  0.442
2000 Huang S, DeGuzman A, Bucana CD, Fidler IJ. Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-kappaB activity. Cytokines, Cellular & Molecular Therapy. 6: 9-17. PMID 10976534 DOI: 10.1080/13684730050515868  0.318
2000 Kumar R, Eue I, Dong Z, Killion JJ, Fidler IJ. Expression of inflammatory cytokines by murine macrophages activated with a new synthetic lipopeptide JT3002. Cancer Biotherapy & Radiopharmaceuticals. 12: 333-40. PMID 10851483 DOI: 10.1089/Cbr.1997.12.333  0.337
2000 Juang SH, Xie K, Xu L, Wang Y, Yoneda J, Fidler IJ. Use of retroviral vectors encoding murine inducible nitric oxide synthase gene to suppress tumorigenicity and cancer metastasis of murine melanoma. Cancer Biotherapy & Radiopharmaceuticals. 12: 167-75. PMID 10851463 DOI: 10.1089/Cbr.1997.12.167  0.459
2000 Bielenberg DR, Fidler IJ, Bucana CD. Constitutive expression of interferon beta in differentiated epithelial cells exposed to environmental stimuli. Cancer Biotherapy & Radiopharmaceuticals. 13: 375-82. PMID 10851428 DOI: 10.1089/Cbr.1998.13.375  0.351
2000 Yoneda J, Killion JJ, Bucana CD, Fidler IJ. Angiogenesis and growth of murine colon carcinoma are dependent on infiltrating leukocytes. Cancer Biotherapy & Radiopharmaceuticals. 14: 221-30. PMID 10850306 DOI: 10.1089/Cbr.1999.14.221  0.451
2000 Shinohara H, Bucana CD, Killion JJ, Fidler IJ. Intensified regression of colon cancer liver metastases in mice treated with irinotecan and the immunomodulator JBT 3002. Journal of Immunotherapy (Hagerstown, Md. : 1997). 23: 321-31. PMID 10838661 DOI: 10.1097/00002371-200005000-00005  0.445
2000 Fidler IJ, Ellis LM. Chemotherapeutic drugs--more really is not better. Nature Medicine. 6: 500-2. PMID 10802697 DOI: 10.1038/74969  0.312
2000 Kumar R, Xie K, Eue I, Dong Z, Killion JJ, Fidler IJ. Differential regulation of type IV collagenases and metalloelastase in murine macrophages by the synthetic bacterial lipopeptide JBT 3002. International Journal of Immunopharmacology. 22: 431-43. PMID 10727754 DOI: 10.1016/S0192-0561(00)00008-4  0.308
2000 Fidler IJ, Schackert G, Zhang RD, Radinsky R, Fujimaki T. The biology of melanoma brain metastasis. Cancer Metastasis Reviews. 18: 387-400. PMID 10721492 DOI: 10.1023/A:1006329410433  0.376
2000 Yang J, Boerm M, McCarty M, Bucana C, Fidler IJ, Zhuang Y, Su B. Mekk3 is essential for early embryonic cardiovascular development. Nature Genetics. 24: 309-13. PMID 10700190 DOI: 10.1038/73550  0.696
2000 Shinohara H, Yano S, Bucana CD, Fidler IJ. Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells. Journal of Immunology (Baltimore, Md. : 1950). 164: 2728-37. PMID 10679114 DOI: 10.4049/Jimmunol.164.5.2728  0.452
2000 Xu L, Yoneda J, Herrera C, Wood J, Killion JJ, Fidler IJ. Inhibition of malignant ascites and growth of human ovarian carcinoma by oral administration of a potent inhibitor of the vascular endothelial growth factor receptor tyrosine kinases. International Journal of Oncology. 16: 445-54. PMID 10675474 DOI: 10.3892/Ijo.16.3.445  0.463
2000 Yano S, Herbst R, Sone S, Fidler I. Production of malignant pleural effusions is dependent on invasion of the pleura and expression of vascular endothelial growth factor/vascular permeability factor by human lung cancer cells Lung Cancer. 29: 217. DOI: 10.1016/S0169-5002(00)80743-6  0.397
1999 Bruns CJ, Harbison MT, Kuniyasu H, Eue I, Fidler IJ. In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice Neoplasia (New York, N.Y.). 1: 50-62. PMID 10935470 DOI: 10.1038/Sj.Neo.7900005  0.47
1999 Multani AS, Ozen M, Sen S, Mandal AK, Price JE, Fan D, Radinsky R, Ali-Osman F, Von Eschenbach AC, Fidler IJ, Pathak S. Amplification of telomeric DNA directly correlates with metastatic potential of human and murine cancers of various histological origin. International Journal of Oncology. 15: 423-9. PMID 10427120 DOI: 10.3892/Ijo.15.3.423  0.421
1999 Fidler IJ. Critical determinants of cancer metastasis: rationale for therapy. Cancer Chemotherapy and Pharmacology. S3-10. PMID 10357552 DOI: 10.1007/S002800051091  0.503
1999 Killion JJ, Radinsky R, Fidler IJ. Orthotopic models are necessary to predict therapy of transplantable tumors in mice. Cancer Metastasis Reviews. 17: 279-84. PMID 10352881 DOI: 10.1023/A:1006140513233  0.433
1999 Bielenberg DR, McCarty MF, Bucana CD, Yuspa SH, Morgan D, Arbeit JM, Ellis LM, Cleary KR, Fidler IJ. Expression of interferon-beta is associated with growth arrest of murine and human epidermal cells. The Journal of Investigative Dermatology. 112: 802-9. PMID 10233775 DOI: 10.1046/J.1523-1747.1999.00566.X  0.72
1999 Bielenberg DR, Bucana CD, Sanchez R, Mulliken JB, Folkman J, Fidler IJ. Progressive growth of infantile cutaneous hemangiomas is directly correlated with hyperplasia and angiogenesis of adjacent epidermis and inversely correlated with expression of the endogenous angiogenesis inhibitor, IFN-beta. International Journal of Oncology. 14: 401-8. PMID 10024670 DOI: 10.3892/Ijo.14.3.401  0.355
1999 Kumar R, Yoneda J, Fidler IJ, Dong Z. GM-CSF-transduced B16 melanoma cells are highly susceptible to lysis by normal murine macrophages and poorly tumorigenic in immune-compromised mice. Journal of Leukocyte Biology. 65: 102-8. PMID 9886252 DOI: 10.1002/Jlb.65.1.102  0.444
1999 Xu L, Xie K, Fidler IJ. Therapy of human ovarian cancer by transfection with the murine interferon beta gene: role of macrophage-inducible nitric oxide synthase. Human Gene Therapy. 9: 2699-708. PMID 9874268 DOI: 10.1089/Hum.1998.9.18-2699  0.456
1999 Slaton JW, Perrotte P, Inoue K, El-Naggar A, Fidler IJ, Swanson DA, Dinney CPN. Ratio Of Matrix Metalloproteases (Mmp) To E-Cadherin (Ecad) Expression Is An Independent Predictor Of Metastasis In Renal Cell Carcinoma (Rcc) The Journal of Urology. 147. DOI: 10.1097/00005392-199904010-00589  0.303
1999 Dinney CPN, Slaton JW, Inoue K, Perrotte P, El-Naggar A, Fidler I, Swanson DA. The Prognostic Significance Of Angiogenic Factor Expression In Renal Cell Carcinoma (Rcc) The Journal of Urology. 140. DOI: 10.1097/00005392-199904010-00564  0.319
1998 Bielenberg DR, Bucana CD, Sanchez R, Donawho CK, Kripke ML, Fidler IJ. Molecular regulation of UVB-induced cutaneous angiogenesis. The Journal of Investigative Dermatology. 111: 864-72. PMID 9804351 DOI: 10.1046/J.1523-1747.1998.00378.X  0.382
1998 Eue I, Kumar R, Dong Z, Killion JJ, Fidler IJ. Induction of nitric oxide production and tumoricidal properties in murine macrophages by a new synthetic lipopeptide JBT3002 encapsulated in liposomes. Journal of Immunotherapy (Hagerstown, Md. : 1997). 21: 340-51. PMID 9789196 DOI: 10.1097/00002371-199809000-00002  0.361
1998 Anzai H, Kitadai Y, Bucana CD, Sanchez R, Omoto R, Fidler IJ. Expression of metastasis-related genes in surgical specimens of human gastric cancer can predict disease recurrence. European Journal of Cancer (Oxford, England : 1990). 34: 558-65. PMID 9713309 DOI: 10.1016/S0959-8049(97)10075-2  0.326
1998 Dong Z, Yoneda J, Kumar R, Fidler IJ. Angiostatin-mediated suppression of cancer metastases by primary neoplasms engineered to produce granulocyte/macrophage colony-stimulating factor. The Journal of Experimental Medicine. 188: 755-63. PMID 9705957 DOI: 10.1084/Jem.188.4.755  0.447
1998 Killion JJ, Fidler IJ. Therapy of cancer metastasis by tumoricidal activation of tissue macrophages using liposome-encapsulated immunomodulators. Pharmacology & Therapeutics. 78: 141-54. PMID 9690815 DOI: 10.1016/S0163-7258(98)00004-7  0.414
1998 Dong Z, Juang SH, Kumar R, Eue I, Xie K, Bielenberg D, Lu W, Bucana C, Yang X, Fidler IJ. Suppression of tumorigenicity and metastasis in murine UV-2237 fibrosarcoma cells by infection with a retroviral vector harboring the interferon-beta gene. Cancer Immunology, Immunotherapy : Cii. 46: 137-46. PMID 9625537 DOI: 10.1007/S002620050472  0.422
1998 Dong Z, Killion JJ, Kumar R, Eue I, Yang X, Lu W, Su B, Fidler IJ. Activation of cytokine production, tumoricidal properties, and tyrosine phosphorylation of MAPKs in human monocytes by a new synthetic lipopeptide, JBT3002. Journal of Leukocyte Biology. 63: 766-74. PMID 9620671 DOI: 10.1002/Jlb.63.6.766  0.342
1998 Juang SH, Xie K, Xu L, Shi Q, Wang Y, Yoneda J, Fidler IJ. Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retroviral vectors harboring the murine inducible nitric oxide synthase gene. Human Gene Therapy. 9: 845-54. PMID 9581907 DOI: 10.1089/Hum.1998.9.6-845  0.411
1998 Xie K, Fidler IJ. Therapy of cancer metastasis by activation of the inducible nitric oxide synthase Cancer and Metastasis Reviews. 17: 55-75. PMID 9544423 DOI: 10.1023/A:1005956721457  0.49
1998 Yoneda J, Kuniyasu H, Crispens MA, Price JE, Bucana CD, Fidler IJ. Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice. Journal of the National Cancer Institute. 90: 447-54. PMID 9521169 DOI: 10.1093/Jnci/90.6.447  0.388
1998 Kumar R, Yoneda J, Bucana CD, Fidler IJ. Regulation of distinct steps of angiogenesis by different angiogenic molecules. International Journal of Oncology. 12: 749-57. PMID 9499433 DOI: 10.3892/Ijo.12.4.749  0.372
1997 Nemeth MA, Wilson MR, Fidler IJ, Pathak S. Increasing metastatic potential is associated with induced chromosome 14 translocations in a previously nonmetastatic murine melanoma cell line. Cancer Genetics and Cytogenetics. 98: 119-25. PMID 9332476 DOI: 10.1016/S0165-4608(96)00421-9  0.363
1997 Yoon SS, Fidler IJ, Beltran PJ, Bucana CD, Wang YF, Fan D. Intratumoral heterogeneity for and epigenetic modulation of mdr-1 expression in murine melanoma. Melanoma Research. 7: 275-87. PMID 9293477 DOI: 10.1097/00008390-199708000-00002  0.402
1997 Xie K, Wang Y, Huang S, Xu L, Bielenberg D, Salas T, McConkey DJ, Jiang W, Fidler IJ. Nitric oxide-mediated apoptosis of K-1735 melanoma cells is associated with downregulation of Bcl-2. Oncogene. 15: 771-9. PMID 9266963 DOI: 10.1038/Sj.Onc.1201239  0.375
1997 Dong Z, Kumar R, Yang X, Fidler IJ. Macrophage-derived metalloelastase is responsible for the generation of angiostatin in Lewis lung carcinoma. Cell. 88: 801-10. PMID 9118223 DOI: 10.1016/S0092-8674(00)81926-1  0.426
1997 Xie K, Huang S, Dong Z, Juang SH, Wang Y, Fidler IJ. Destruction of bystander cells by tumor cells transfected with inducible nitric oxide (NO) synthase gene. Journal of the National Cancer Institute. 89: 421-7. PMID 9091643 DOI: 10.1093/Jnci/89.6.421  0.444
1997 Ellis LM, Fidler IJ. Angiogenesis and metastasis. European Journal of Cancer (Oxford, England : 1990). 2451-60. PMID 9059333 DOI: 10.1016/S0959-8049(96)00389-9  0.356
1997 Beltran PJ, Fan D, Fidler IJ, O'Brian CA. Chemosensitization of cancer cells by the staurosporine derivative CGP 41251 in association with decreased P-glycoprotein phosphorylation Biochemical Pharmacology. 53: 245-247. PMID 9037258 DOI: 10.1016/S0006-2952(96)00718-6  0.345
1997 Singh RK, Gutman M, Llansa N, Fidler IJ. Interferon-beta prevents the upregulation of interleukin-8 expression in human melanoma cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 16: 577-84. PMID 8877727 DOI: 10.1089/Jir.1996.16.577  0.333
1996 Dave BJ, Singh R, Fidler IJ, Pathak S. Chromosome 14 alteration is associated with increased collagenase expression and the metastatic potential of murine melanomas. Cancer Genetics and Cytogenetics. 92: 66-72. PMID 8956875 DOI: 10.1016/S0165-4608(96)00160-4  0.36
1996 Xie K, Huang S, Wang Y, Beltran PJ, Juang SH, Dong Z, Reed JC, McDonnell TJ, McConkey DJ, Fidler IJ. Bcl-2 protects cells from cytokine-induced nitric-oxide-dependent apoptosis Cancer Immunology, Immunotherapy. 43: 109-115. PMID 8954145 DOI: 10.1007/S002620050310  0.399
1996 Fujimaki T, Price JE, Fan D, Bucana CD, Itoh K, Kirino T, Fidler IJ. Selective growth of human melanoma cells in the brain parenchyma of nude mice. Melanoma Research. 6: 363-71. PMID 8908596 DOI: 10.1097/00008390-199610000-00003  0.312
1996 Xie K, Dong Z, Fidler IJ. Activation of nitric oxide synthase gene for inhibition of cancer metastasis. Journal of Leukocyte Biology. 59: 797-803. PMID 8691063 DOI: 10.1002/Jlb.59.6.797  0.478
1996 Anzai H, Kitadai Y, Bucana CD, Sanchez R, Omoto R, Fidler IJ. Intratumoral heterogeneity and inverse correlation between expression of E-cadherin and collagenase type IV in human gastric carcinomas. Differentiation; Research in Biological Diversity. 60: 119-27. PMID 8641546 DOI: 10.1046/J.1432-0436.1996.6020119.X  0.334
1995 Killion JJ, Fidler IJ. Systemic targeting of liposome-encapsulated immunomodulators to macrophages for treatment of cancer metastasis. Immunomethods. 4: 273-9. PMID 7820457 DOI: 10.1006/Immu.1994.1029  0.441
1995 Gutman M, Fidler IJ. Biology of human colon cancer metastasis. World Journal of Surgery. 19: 226-34. PMID 7754628 DOI: 10.1007/Bf00308631  0.498
1995 Singh RK, Gutman M, Bucana CD, Sanchez R, Llansa N, Fidler IJ. Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proceedings of the National Academy of Sciences of the United States of America. 92: 4562-6. PMID 7753843 DOI: 10.1073/Pnas.92.10.4562  0.339
1995 Gutman M, Beltran PJ, Fan D, Delworth MG, Singh RK, Wilson MR, Fidler IJ. Treatment of nude mice with 4-amidinoindan -1- one2 '- amidinohydrazone, a new S-adenosylmethionine decarboxylase inhibitor, delays growth and inhibits metastasis of human melanoma cells. Melanoma Research. 5: 147-54. PMID 7640515 DOI: 10.1097/00008390-199506000-00002  0.391
1995 Fidler IJ. Modulation of the organ microenvironment for treatment of cancer metastasis. Journal of the National Cancer Institute. 87: 1588-92. PMID 7563201 DOI: 10.1093/Jnci/87.21.1588  0.308
1995 Ellis LM, Fidler IJ. Angiogenesis and breast cancer metastasis The Lancet. 346: 388-390. PMID 7542721 DOI: 10.1016/S0140-6736(95)92774-3  0.302
1995 Xie K, Huang S, Dong Z, Juang SH, Gutman M, Xie QW, Nathan C, Fidler IJ. Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells. The Journal of Experimental Medicine. 181: 1333-43. PMID 7535333 DOI: 10.1084/Jem.181.4.1333  0.387
1995 Gutman M, Singh RK, Yoon S, Xie K, Bucana CD, Fidler IJ. Leukocyte-induced angiogenesis and subcutaneous growth of B16 melanoma. Cancer Biotherapy. 9: 163-70. PMID 7529086 DOI: 10.1089/Cbr.1994.9.163  0.441
1995 Dinney CPN, Fishbeck R, Singh RK, Eve B, Pathak S, Brown N, Xie B, Fan D, Bucana CD, Fidler IJ, Killion JJ. Isolation and Characterization of Metastatic Variants from Human Transitional Cell Carcinoma Passaged by Orthotopic Implantation in Athymic Nude Mice Journal of Urology. 154: 1532-1538. DOI: 10.1016/S0022-5347(01)66923-4  0.435
1994 Gohji K, Nakajima M, Fabra A, Bucana CD, von Eschenbach AC, Tsuruo T, Fidler IJ. Regulation of gelatinase production in metastatic renal cell carcinoma by organ-specific fibroblasts. Japanese Journal of Cancer Research : Gann. 85: 152-60. PMID 8144397 DOI: 10.1111/J.1349-7006.1994.Tb02076.X  0.418
1994 Gohji K, Fidler IJ, Tsan R, Radinsky R, von Eschenbach AC, Tsuruo T, Nakajima M. Human recombinant interferons-beta and -gamma decrease gelatinase production and invasion by human KG-2 renal-carcinoma cells. International Journal of Cancer. 58: 380-4. PMID 8050821 DOI: 10.1002/Ijc.2910580313  0.339
1994 Huang S, Singh RK, Xie K, Gutman M, Berry KK, Bucana CD, Fidler IJ, Bar-Eli M. Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells. Cancer Immunology, Immunotherapy : Cii. 39: 231-8. PMID 7954525 DOI: 10.1007/Bf01525986  0.417
1994 Fidler IJ, Wilmanns C, Staroselsky A, Radinsky R, Dong Z, Fan D. Modulation of tumor cell response to chemotherapy by the organ environment. Cancer Metastasis Reviews. 13: 209-22. PMID 7923551 DOI: 10.1007/Bf00689637  0.476
1994 Dong Z, Radinsky R, Fan D, Tsan R, Bucana CD, Wilmanns C, Fidler IJ. Organ-specific modulation of steady-state mdr gene expression and drug resistance in murine colon cancer cells. Journal of the National Cancer Institute. 86: 913-20. PMID 7910854 DOI: 10.1093/Jnci/86.12.913  0.38
1994 Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell. 79: 185-8. PMID 7525076 DOI: 10.1016/0092-8674(94)90187-2  0.343
1994 Fan D, Regenass U, Beltran PJ, Campbell TE, Bielenberg D, Fidler IJ. Protein kinase C inhibitor staurosporin derivative CGP 41251 reverses MDR in murine and human cancer cell lines Anti-Cancer Drugs. 5: 29. DOI: 10.1097/00001813-199409001-00065  0.354
1994 Fan D, Beltran PJ, Gutman M, Wang Y, Bucana CD, Bielenberg D, Fidler IJ. The MDR1-mediated multidrug resistance is regulated by cell density and tumor volume in colon carcinomas Anti-Cancer Drugs. 5: 8. DOI: 10.1097/00001813-199409001-00014  0.378
1994 Fidler IJ, Kleinerman ES. Clinical application of phospholipid liposomes containing macrophage activators for therapy of cancer metastasis Advanced Drug Delivery Reviews. 13: 325-340. DOI: 10.1016/0169-409X(94)90018-3  0.371
1993 Allam A, Gioioso D, Taghian A, Duffy M, Fidler IJ, Suit HD. Intrinsic radiation sensitivity: no correlation with the metastatic potential of human and murine tumor cell lines. Journal of the National Cancer Institute. 85: 1954-7. PMID 8230288 DOI: 10.1093/Jnci/85.23.1954  0.403
1993 Killion JJ, Radinsky R, Dong Z, Fishbeck R, Whitworth P, Fidler IJ. The immunogenic properties of drug-resistant murine tumor cells do not correlate with expression of the MDR phenotype. Cancer Immunology, Immunotherapy : Cii. 36: 381-6. PMID 8098991 DOI: 10.1007/Bf01742254  0.423
1993 Fabra A, Nakajima M, Bucana CD, Fidler IJ. Modulation of the invasive phenotype of human colon carcinoma cells by organ specific fibroblasts of nude mice. Differentiation; Research in Biological Diversity. 52: 101-10. PMID 1286773 DOI: 10.1111/J.1432-0436.1992.Tb00504.X  0.425
1992 Fidler IJ. Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis. Cancer Metastasis Reviews. 10: 229-43. PMID 1764766 DOI: 10.1007/Bf00050794  0.389
1992 Fidler IJ. The biology of cancer metastasis or, 'you cannot fix it if you do not know how it works'. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 13: 551-4. PMID 1755831 DOI: 10.1002/bies.950131010  0.305
1992 Fidler IJ. 7th Jan Waldenström Lecture. The biology of human cancer metastasis. Acta Oncologica (Stockholm, Sweden). 30: 668-75. PMID 1659837 DOI: 10.3109/02841869109092438  0.508
1992 Staroselsky AN, Radinsky R, Fidler IJ, Pathak S, Chernajovsky Y, Frost P. The use of molecular genetic markers to demonstrate the effect of organ environment on clonal dominance in a human renal-cell carcinoma grown in nude mice. International Journal of Cancer. 51: 130-8. PMID 1563832 DOI: 10.1002/Ijc.2910510123  0.426
1992 Fidler IJ. Therapy of disseminated melanoma by liposome-activated macrophages. World Journal of Surgery. 16: 270-6. PMID 1561809 DOI: 10.1007/Bf02071531  0.494
1992 Kleinerman ES, Raymond AK, Bucana CD, Jaffe N, Harris MB, Krakoff IH, Benjamin R, Fidler IJ. Unique histological changes in lung metastases of osteosarcoma patients following therapy with liposomal muramyl tripeptide (CGP 19835A lipid) Cancer Immunology Immunotherapy. 34: 211-220. PMID 1537053 DOI: 10.1007/Bf01741788  0.342
1992 Wilmanns C, Fan D, O'Brian CA, Bucana CD, Fidler IJ. Orthotopic and ectopic organ environments differentially influence the sensitivity of murine colon carcinoma cells to doxorubicin and 5-fluorouracil International Journal of Cancer. 52: 98-104. PMID 1500231 DOI: 10.1002/Ijc.2910520118  0.44
1992 Ullrich SE, Fidler IJ. Liposomes containing muramyl tripeptide phosphatidylethanolamine (MTP-PE) are excellent adjuvants for induction of an immune response to protein and tumor antigens Journal of Leukocyte Biology. 52: 489-494. PMID 1431559 DOI: 10.1002/Jlb.52.5.489  0.3
1992 Stephenson RA, Dinney CP, Gohji K, Ordóñez NG, Killion JJ, Fidler IJ. Metastatic model for human prostate cancer using orthotopic implantation in nude mice. Journal of the National Cancer Institute. 84: 951-7. PMID 1378502 DOI: 10.1093/Jnci/84.12.951  0.321
1992 Fidler IJ. Metastasis as a consequence of aberrant homeostasis Clinical and Experimental Metastasis. 10: 5-7. DOI: 10.1007/Bf00305899  0.329
1991 Fidler IJ, Naito S, Pathak S. Orthotopic implantation is essential for the selection, growth and metastasis of human renal cell cancer in nude mice [corrected]. Cancer Metastasis Reviews. 9: 149-65. PMID 2253314 DOI: 10.1007/Bf00046341  0.468
1991 Nakajima M, Morikawa K, Fabra A, Bucana CD, Fidler IJ. Influence of organ environment on extracellular matrix degradative activity and metastasis of human colon carcinoma cells. Journal of the National Cancer Institute. 82: 1890-8. PMID 2174463 DOI: 10.1093/Jnci/82.24.1890  0.46
1991 Nii A, Fan D, Fidler IJ. Cytotoxic potential of liposomes containing tumor necrosis factor-alpha against sensitive and resistant target cells. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 10: 13-9. PMID 2012796 DOI: 10.1097/00002371-199102000-00003  0.391
1991 Pak CC, Fidler IJ. Liposomal delivery of biological response modifiers to macrophages Biotherapy. 3: 55-64. PMID 2009214 DOI: 10.1007/Bf02175099  0.407
1991 O'Brian CA, Fan D, Ward NE, Dong Z, Iwamoto L, Gupta KP, Earnest LE, Fidler IJ. Transient enhancement of multidrug resistance by the bile acid deoxycholate in murine fibrosarcoma cells in vitro Biochemical Pharmacology. 41: 797-806. PMID 1998534 DOI: 10.1016/0006-2952(91)90083-H  0.356
1991 Naito S, Kumazawa J, von Eschenbach AC, Fidler IJ. Metastatic heterogeneity of human renal cell carcinoma. Urologia Internationalis. 90-5. PMID 1949389 DOI: 10.1159/000282262  0.34
1991 Nii A, Utsugi T, Fan D, Denkins Y, Pak C, Brown D, van Hoogevest P, Fidler IJ. Optimization of the liposomes encapsulating a new lipopeptide CGP 31362 for efficient activation of tumoricidal properties in monocytes and macrophages. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 10: 236-46. PMID 1931862 DOI: 10.1097/00002371-199108000-00002  0.337
1991 Utsugi T, Dinney CP, Killion JJ, Fidler IJ. In situ activation of mouse macrophages and therapy of spontaneous renal cell cancer metastasis by liposomes containing the lipopeptide CGP 31362. Cancer Immunology, Immunotherapy : Cii. 33: 375-81. PMID 1878891 DOI: 10.1007/Bf01741597  0.4
1991 Utsugi T, Nii A, Fan D, Pak CC, Denkins Y, van Hoogevest P, Fidler IJ. Comparative efficacy of liposomes containing synthetic bacterial cell wall analogues for tumoricidal activation of monocytes and macrophages. Cancer Immunology, Immunotherapy : Cii. 33: 285-92. PMID 1868486 DOI: 10.1007/Bf01756592  0.333
1991 Fidler IJ. Cancer metastasis. British Medical Bulletin. 47: 157-77. PMID 1863845 DOI: 10.1093/oxfordjournals.bmb.a072453  0.311
1991 Saiki I, Naito S, Yoneda J, Azuma I, Price JE, Fidler IJ. Characterization of the invasive and metastatic phenotype in human renal cell carcinoma. Clinical & Experimental Metastasis. 9: 551-66. PMID 1752085 DOI: 10.1007/Bf01768583  0.435
1990 Frangos DN, Killion JJ, Fan D, Fishbeck R, von Eschenbach AC, Fidler IJ. The development of liposomes containing interferon alpha for the intravesical therapy of human superficial bladder cancer. The Journal of Urology. 143: 1252-6. PMID 2342197 DOI: 10.1016/S0022-5347(17)40248-5  0.34
1990 Fidler IJ, Radinsky R. Genetic control of cancer metastasis. Journal of the National Cancer Institute. 82: 166-8. PMID 2296042 DOI: 10.1093/Jnci/82.3.166  0.373
1990 Whitworth PW, Pak CC, Esgro J, Kleinerman ES, Fidler IJ. Macrophages and cancer. Cancer Metastasis Reviews. 8: 319-51. PMID 2182211 DOI: 10.1007/Bf00052607  0.497
1990 Morikawa K, Morikawa R, Killion JJ, Fan D, Fidler IJ. Isolation of human colon carcinoma cells for resistance to a single interferon associated with cross-resistance to multiple recombinant interferons: alpha, beta, and gamma. Journal of the National Cancer Institute. 82: 517-22. PMID 2138228 DOI: 10.1093/Jnci/82.6.517  0.318
1989 Pak CC, Fidler IJ. Activated macrophages distinguish undifferentiated-tumorigenic from differentiated-nontumorigenic murine erythroleukemia cells Differentiation. 41: 49-55. PMID 2806772 DOI: 10.1111/J.1432-0436.1989.Tb00731.X  0.317
1989 Li L, Price JE, Fan D, Zhang Rd, Bucana CD, Fidler IJ. Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites Journal of the National Cancer Institute. 81: 1406-1412. PMID 2778827 DOI: 10.1093/Jnci/81.18.1406  0.471
1989 Killion JJ, Fan D, Bucana CD, Frangos DN, Price JE, Fidler IJ. Augmentation of antiproliferative activity of interferon alfa against human bladder tumor cell lines by encapsulation of interferon alfa within liposomes Journal of the National Cancer Institute. 81: 1387-1392. PMID 2778824 DOI: 10.1093/Jnci/81.18.1387  0.319
1989 Schackert HK, Fidler IJ. Development of an animal model to study the biology of recurrent colorectal cancer originating from mesenteric lymph system metastases. International Journal of Cancer. 44: 177-81. PMID 2744889 DOI: 10.1002/Ijc.2910440131  0.418
1989 Connor J, Bucana C, Fidler IJ, Schroit AJ. Differentiation-dependent expression of phosphatidylserine in mammalian plasma membranes: quantitative assessment of outer-leaflet lipid by prothrombinase complex formation. Proceedings of the National Academy of Sciences of the United States of America. 86: 3184-8. PMID 2717615 DOI: 10.1073/Pnas.86.9.3184  0.339
1989 Mccready DR, Balch CM, Fidler IJ, Murray JL. Lack of comparability between binding of monoclonal antibodies to melanoma cells in vitro and localization in vivo Journal of the National Cancer Institute. 81: 682-687. PMID 2709424 DOI: 10.1093/Jnci/81.9.682  0.425
1989 O'Brian CA, Fan D, Ward NE, Seid C, Fidler IJ. Level of protein kinase C activity correlates directly with resistance to adriamycin in murine fibrosarcoma cells Febs Letters. 246: 78-82. PMID 2707442 DOI: 10.1016/0014-5793(89)80257-1  0.322
1989 Albini A, Aukerman SL, Ogle RC, Noonan DM, Fridman R, Martin GR, Fidler IJ. The in vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants. Clinical & Experimental Metastasis. 7: 437-51. PMID 2706831 DOI: 10.1007/Bf01753664  0.39
1989 Naito S, Walker SM, Fidler IJ. In vivo selection of human renal cell carcinoma cells with high metastatic potential in nude mice. Clinical & Experimental Metastasis. 7: 381-9. PMID 2706827 DOI: 10.1007/Bf01753659  0.42
1989 Fidler IJ. Origin and biology of cancer metastasis. Cytometry. 10: 673-80. PMID 2684578 DOI: 10.1002/cyto.990100602  0.371
1989 Johnson JW, Nayar R, Killion JJ, von Eschenbach AC, Fidler IJ. Binding of liposomes to human bladder tumor epithelial cell lines: implications for an intravesical drug delivery system for the treatment of bladder cancer. Selective Cancer Therapeutics. 5: 147-55. PMID 2623380 DOI: 10.1089/Sct.1989.5.147  0.413
1989 Schackert G, Price JE, Bucana CD, Fidler IJ. Unique patterns of brain metastasis produced by different human carcinomas in athymic nude mice International Journal of Cancer. 44: 892-897. PMID 2583868 DOI: 10.1002/Ijc.2910440524  0.392
1989 Fan D, Chakrabarty S, Seid C, Bell CW, Schackert H, Morikawa K, Fidler IJ. Clonal stimulation or inhibition of human colon carcinomas and human renal carcinomas mediated by transforming growth factor-beta 1. Cancer Communications. 1: 117-25. PMID 2561734 DOI: 10.3727/095535489820875327  0.374
1988 Hisano G, Fidler IJ. Systemic activation of macrophages by liposome-entrapped muramyl tripeptide in mice pretreated with the chemotherapeutic agent adriamycin. Cancer Immunology, Immunotherapy : Cii. 14: 61-6. PMID 6965228 DOI: 10.1007/Bf00200168  0.327
1988 Schackert G, Fidler IJ. Development of in vivo models for studies of brain metastasis. International Journal of Cancer. 41: 589-94. PMID 3356491 DOI: 10.1002/Ijc.2910410419  0.479
1988 Fidler IJ. The biology of melanoma metastasis. The Journal of Dermatologic Surgery and Oncology. 14: 875-81. PMID 3294269 DOI: 10.1111/j.1524-4725.1988.tb03591.x  0.365
1988 Schackert G, Simmons RD, Buzbee TM, Hume DA, Fidler IJ. Macrophage infiltration into experimental brain metastases: Occurrence through an intact blood-brain barrier Journal of the National Cancer Institute. 80: 1027-1034. PMID 3261801 DOI: 10.1093/Jnci/80.13.1027  0.35
1988 Price JE, Sauder DN, Fidler IJ. Tumorigenicity and metastatic behavior in nude mice of two human squamous cell carcinoma lines that differ in production of the cytokine ETAF/IL-1 Journal of Investigative Dermatology. 91: 258-262. PMID 3045210 DOI: 10.1111/1523-1747.Ep12470396  0.45
1988 Price JE, Naito S, Fidler IJ. Growth in an organ microenvironment as a selective process in metastasis Clinical & Experimental Metastasis. 6: 91-102. PMID 2961497 DOI: 10.1007/BF01580409  0.303
1987 Naito S, Giavazzi R, Walker SM, Itoh K, Mayo J, Fidler IJ. Growth and metastatic behavior of human tumor cells implanted into nude and beige nude mice. Clinical & Experimental Metastasis. 5: 135-46. PMID 3594971 DOI: 10.1007/Bf00058059  0.43
1987 Fidler IJ, Balch CM. The biology of cancer metastasis and implications for therapy. Current Problems in Surgery. 24: 129-209. PMID 3568753 DOI: 10.1016/0011-3840(87)90002-5  0.322
1987 Naito S, Eschenbach ACV, Fidler IJ. Different Growth Pattern and Biologic Behavior of Human Renal Cell Carcinoma Implanted Into Different Organs of Nude Mice Journal of the National Cancer Institute. 78: 377-385. DOI: 10.1093/Jnci/78.2.377  0.443
1987 Brande MC, Algood CB, Wishnow KI, Fidler IJ. Invasion of Organ-Cultured Urinary Bladder by Spheroid-Derived Tumor CellS Journal of Urology. 137. DOI: 10.1016/S0022-5347(17)76087-9  0.393
1986 Nayar R, Fidler IJ. The systemic activation of macrophages by liposomes containing immunomodulators. Springer Seminars in Immunopathology. 8: 413-28. PMID 4089759 DOI: 10.1007/Bf01857394  0.33
1986 Aukerman SL, Siciliano MJ, Fidler IJ. Heterogeneity of isozyme expression in tumor cells does not correlate with metastatic potential. Clinical & Experimental Metastasis. 4: 177-89. PMID 3742891 DOI: 10.1007/Bf00117931  0.464
1986 Saiki I, Nayar R, Bucana C, Fidler IJ. A microassay for the rapid and selective binding of cells from solid tumors to mouse macrophages. Cancer Immunology, Immunotherapy : Cii. 22: 125-31. PMID 3719592 DOI: 10.1007/BF00199126  0.334
1986 Frost P, Fidler IJ. Biology of metastasis. Cancer. 58: 550-3. PMID 3719550 DOI: 10.1002/1097-0142(19860715)58:2+<550::Aid-Cncr2820581324>3.0.Co;2-Z  0.442
1986 Fidler IJ. Rationale and methods for the use of nude mice to study the biology and therapy of human cancer metastasis. Cancer Metastasis Reviews. 5: 29-49. PMID 2942306 DOI: 10.1007/Bf00049529  0.483
1986 Giavazzi R, Jessup JM, Campbell DE, Walker SM, Fidler IJ. Experimental Nude Mouse Model of Human Colorectal Cancer Liver Metastases Journal of the National Cancer Institute. 77: 1303-1308. DOI: 10.1093/Jnci/77.6.1303  0.355
1986 Aukerman SL, Price JE, Fidler IJ. Different deficiencies in the prevention of tumorigenic-low-metastatic murine K-1735b melanoma cells from producing metastases. Journal of the National Cancer Institute. 77: 915-924. DOI: 10.1093/Jnci/77.4.915  0.463
1986 Nicolson GL, Fidler IJ, Poste G. Effects of Tertiary Amine Local Anesthetics on the Blood-Borne Implantation and Cell Surface Properties of Metastatic Mouse Melanoma Cells Journal of the National Cancer Institute. 76: 511-519. DOI: 10.1093/Jnci/76.3.511  0.45
1985 Xu Z, Fidler IJ. The in situ activation of cytotoxic properties in murine Kupffer cells by the systemic administration of whole Mycobacterium bovis organisms or muramyl tripeptide. Cancer Immunology, Immunotherapy : Cii. 18: 118-22. PMID 6391654 DOI: 10.1007/Bf00205745  0.444
1985 Schroit AJ, Tanaka Y, Madsen J, Fidler IJ. The recognition of red blood cells by macrophages: role of phosphatidylserine and possible implications of membrane phospholipid asymmetry. Biology of the Cell. 51: 227-38. PMID 6240306 DOI: 10.1111/J.1768-322X.1984.Tb00303.X  0.302
1985 Kleinerman ES, Wiltrout RH, Zicht R, Fidler IJ. Human lymphokine preparations which generate tumoricidal properties of human monocytes in vitro may be distinct from gamma interferon. Cancer Immunology, Immunotherapy : Cii. 20: 151-7. PMID 3930068 DOI: 10.1007/Bf00205682  0.317
1985 Koff WC, Fogler WE, Gutterman J, Fidler IJ. Efficient activation of human blood monocytes to a tumoricidal state by liposomes containing human recombinant gamma interferon. Cancer Immunology, Immunotherapy : Cii. 19: 85-9. PMID 3921232 DOI: 10.1007/Bf00199714  0.327
1985 Kleinerman ES, Fogler WE, Fidler IJ. Intracellular activation of human and rodent macrophages by human lymphokines encapsulated in liposomes. Journal of Leukocyte Biology. 37: 571-84. PMID 3920339 DOI: 10.1002/Jlb.37.5.571  0.351
1984 Fidler IJ, Burger MM. UICC Study Group in basic and clinical cancer research: cancer metastasis. International Journal of Cancer. Journal International Du Cancer. 33: 1-3. PMID 6693188 DOI: 10.1002/Ijc.2910330102  0.301
1984 Koff WC, Fidler IJ, Showalter SD, Chakrabarty MK, Hampar B, Ceccorulli LM, Kleinerman ES. Human monocytes activated by immunomodulators in liposomes lyse herpesvirus-infected but not normal cells. Science (New York, N.Y.). 224: 1007-9. PMID 6426057 DOI: 10.1126/Science.6426057  0.336
1984 Fidler IJ, Kleinerman ES. Lymphokine-activated human blood monocytes destroy tumor cells but not normal cells under cocultivation conditions. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 2: 937-43. PMID 6379124 DOI: 10.1200/Jco.1984.2.8.937  0.388
1984 Fidler IJ, Kozlowski JM. The heterogeneous nature of metastatic neoplasms: implications for the treatment of cancer. Urology. 23: 29-38. PMID 6369719 DOI: 10.1016/S0090-4295(84)80064-3  0.455
1984 Kozlowski JM, Hart IR, Fidler IJ, Hanna N. A Human Melanoma Line Heterogeneous With Respect to Metastatic Capacity in Athymic Nude Mice Journal of the National Cancer Institute. 72: 913-917. DOI: 10.1093/Jnci/72.4.913  0.407
1983 Fidler IJ, Poste G. Macrophages and cancer metastasis. Advances in Experimental Medicine and Biology. 155: 65-75. PMID 6984285 DOI: 10.1007/978-1-4684-4394-3_5  0.445
1983 Fidler IJ, Poste G. Macrophage-mediated destruction of malignant tumor cells and new strategies for the therapy of metastatic disease. Springer Seminars in Immunopathology. 5: 161-74. PMID 6755782 DOI: 10.1007/Bf00199794  0.407
1983 Thistlethwaithe P, Davidson DD, Fidler IJ, Roth JA. Syngeneic humoral immune responses to tumor-associated antigens expressed by K-1735 UV-induced melanoma and its metastases. Cancer Immunology, Immunotherapy : Cii. 15: 11-6. PMID 6553502 DOI: 10.1007/Bf00199455  0.36
1982 Hanna N, Davis TW, Fidler IJ. Environmental and genetic factors determine the level of NK activity of nude mice and affect their suitability as models for experimental metastasis. International Journal of Cancer. 30: 371-6. PMID 7129682 DOI: 10.1002/Ijc.2910300319  0.382
1982 Fidler IJ, Hart IR. Biological diversity in metastatic neoplasms: origins and implications. Science (New York, N.Y.). 217: 998-1003. PMID 7112116 DOI: 10.1126/Science.7112116  0.424
1982 Cifone MA, Fidler IJ. Increasing metastatic potential is associated with increasing genetic instability of clones isolated from murine neoplasms. Proceedings of the National Academy of Sciences of the United States of America. 78: 6949-52. PMID 6947269 DOI: 10.1073/Pnas.78.11.6949  0.413
1982 Fidler IJ, Poste G. The biologic diversity of cancer metastases. Hospital Practice (Office Ed.). 17: 57-64. PMID 6809572 DOI: 10.1080/21548331.1982.11698073  0.375
1982 Fidler IJ, Hart IR. The origin of metastatic heterogeneity in tumors. European Journal of Cancer. 17: 487-94. PMID 6271554 DOI: 10.1016/0014-2964(81)90049-9  0.449
1982 Talmadge JE, Fidler IJ. Enhanced Metastatic Potential of Tumor Cells Harvested From Spontaneous Metastases of Heterogeneous Murine Tumors Journal of the National Cancer Institute. 69: 975-980. DOI: 10.1093/Jnci/69.4.975  0.459
1982 Pollack VA, Fidler IJ. Use of Young Nude Mice for Selection of Subpopulations of Cells With Increased Metastatic Potential From Nonsyngeneic Neoplasms Journal of the National Cancer Institute. 69: 137-141. DOI: 10.1093/Jnci/69.1.137  0.441
1982 Sone S, Fidler I. In situ activation of tumoricidal properties in rat alveolar macrophages and rejection of experimental lung metastases by intravenous injections of Nocardia rubra cell wall skeleton Cancer Immunology Immunotherapy. 12. DOI: 10.1007/Bf00199175  0.332
1981 Sone S, Fidler IJ. In vitro activation of tumoricidal properties in rat alveolar macrophages by synthetic muramyl dipeptide encapsulated in liposomes. Cellular Immunology. 57: 42-50. PMID 7214534 DOI: 10.1016/0008-8749(81)90118-0  0.359
1981 Hart IR, Fidler IJ. The implications of tumor heterogeneity for studies on the biology of cancer metastasis. Biochimica Et Biophysica Acta. 651: 37-50. PMID 7025905 DOI: 10.1016/0304-419X(81)90004-4  0.422
1981 Poste G, Doll J, Fidler IJ. Interactions among clonal subpopulations affect stability of the metastatic phenotype in polyclonal populations of B16 melanoma cells Proceedings of the National Academy of Sciences of the United States of America. 78: 6226-6230. PMID 6947225 DOI: 10.1073/Pnas.78.10.6226  0.31
1981 Fidler IJ, Sone S, Fogler WE, Barnes ZL. Eradication of spontaneous metastases and activation of alveolar macrophages by intravenous injection of liposomes containing muramyl dipeptide. Proceedings of the National Academy of Sciences of the United States of America. 78: 1680-4. PMID 6940181 DOI: 10.1073/Pnas.78.3.1680  0.396
1981 Raz A, Hanna N, Fidler IJ. In vivo isolation of a metastatic tumor cell variant involving selective and nonadaptive processes12 3 Journal of the National Cancer Institute. 66: 183-189. PMID 6935459 DOI: 10.1093/Jnci/66.1.183  0.446
1981 Hanna N, Fidler IJ. Relationship Between Metastatic Potential and Resistance to Natural Killer Cellmediated Cytotoxicity in Three Murine Tumor Systems Journal of the National Cancer Institute. 66: 1183-1190. DOI: 10.1093/Jnci/66.6.1183  0.35
1981 Hart IR, Fogler WE, Poste G, Fidler IJ. Toxicity studies of liposome-encapsulated immunomodulators administered intravenously to dogs and mice Cancer Immunology, Immunotherapy. 10: 157-166. DOI: 10.1007/Bf00205887  0.369
1981 Fidler I, Davis T, Raz A. The influence of host health and environment on natural cytotoxicity of mouse macrophages Cancer Immunology Immunotherapy. 11. DOI: 10.1007/Bf00199490  0.366
1980 Fogler WE, Raz A, Fidler IJ. In situ activation of murine macrophages by liposomes containing lymphokines. Cellular Immunology. 53: 214-9. PMID 7407932 DOI: 10.1016/0008-8749(80)90440-2  0.348
1980 Fidler IJ. Therapy of spontaneous metastases by intravenous injection of liposomes containing lymphokines. Science (New York, N.Y.). 208: 1469-71. PMID 7384789 DOI: 10.1126/Science.7384789  0.363
1980 Raz A, Bucana C, McLellan W, Fidler IJ. Distribution of membrane anionic sites on B16 melanoma variants with differing lung colonising potential Nature. 284: 363-364. PMID 7360272 DOI: 10.1038/284363A0  0.347
1980 Poste G, Fidler IJ. The pathogenesis of cancer metastasis. Nature. 283: 139-46. PMID 6985715 DOI: 10.1038/283139A0  0.421
1980 Hanna N, Fidler IJ. Role of natural killer cells in the destruction of circulating tumor emboli. Journal of the National Cancer Institute. 65: 801-9. PMID 6932529 DOI: 10.1093/Jnci/65.4.801  0.476
1980 Cifone MA, Fidler IJ. Correlation of patterns of anchorage-independent growth with in vivo behavior of cells from a murine fibrosarcoma. Proceedings of the National Academy of Sciences of the United States of America. 77: 1039-43. PMID 6928659 DOI: 10.1073/Pnas.77.2.1039  0.483
1980 Hart IR, Fidler IJ. Cancer invasion and metastasis. The Quarterly Review of Biology. 55: 121-42. PMID 6251508 DOI: 10.1016/B978-0-12-386456-7.01910-9  0.486
1980 Fidler IJ, Fogler WE, Barnes Z, Fisher K. The treatment of established micrometastases with syngeneic macrophages. Advances in Experimental Medicine and Biology. 399-410. PMID 397756 DOI: 10.1007/978-1-4684-8914-9_37  0.407
1980 Hart IR, Raz A, Fidler IJ. Effect of cytoskeleton-disrupting agents on the metastatic behavior of melanoma cells Journal of the National Cancer Institute. 64: 891-900. DOI: 10.1093/Jnci/64.4.891  0.454
1980 Fidler IJ, Kripke ML. Tumor cell antigenicity, host immunity, and cancer metastasis Cancer Immunology Immunotherapy. 7: 201-205. DOI: 10.1007/Bf00205466  0.412
1979 Cifone MA, Kripke ML, Fidler IJ. Growth rate and chromosome number of tumor cell lines with different metastatic potential Journal of Supramolecular and Cellular Biochemistry. 11: 467-476. PMID 544925 DOI: 10.1002/Jss.400110405  0.391
1979 Poste G, Kirsh R, Fidler IJ. Cell surface receptors for lymphokines. I. The possible role of glycolipids as receptors for macrophage migration inhibitory factor (MIF) and macrophage activation factor (MAF). Cellular Immunology. 44: 71-88. PMID 378418 DOI: 10.1016/0008-8749(79)90029-7  0.313
1979 Raz A, Fogler W, Fidler I. The effects of experimental conditions on the expression of in vitro-mediated tumor cytotoxicity mediated by murine macrophages Cancer Immunology Immunotherapy. 7. DOI: 10.1007/Bf00199193  0.419
1978 Fidler IJ, Gersten DM, Hart IR. The biology of cancer invasion and metastasis. Advances in Cancer Research. 28: 149-250. PMID 360795 DOI: 10.1016/S0065-230X(08)60648-X  0.497
1978 Fidler IJ, Roblin RO, Poste G. In vitro tumoricidal activity of macrophages against virus-transformed lines with temperature-dependent transformed phenotypic characteristics. Cellular Immunology. 38: 131-46. PMID 208781 DOI: 10.1016/0008-8749(78)90039-4  0.308
1977 Fidler IJ, Nicolson GL. Organ selectivity for implantation survival and growth of B16 melanoma variant tumor lines. Journal of the National Cancer Institute. 57: 1199-202. PMID 1003551 DOI: 10.1093/Jnci/57.5.1199  0.431
1977 Gersten DM, Fogler WE, Fidler IJ. Quantitative analysis of macrophage phagocytosis by uptake of particulate 192iridium. Journal of Immunological Methods. 17: 349-59. PMID 915303 DOI: 10.1016/0022-1759(77)90117-X  0.3
1977 Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor Science. 197: 893-895. PMID 887927 DOI: 10.1126/Science.887927  0.428
1977 Fidler IJ, Gersten DM, Riggs CW. Relationship of host immune status to tumor cell arrest, distribution, and survival in experimental metastasis. Cancer. 40: 46-55. PMID 880570 DOI: 10.1002/1097-0142(197707)40:1<46::Aid-Cncr2820400110>3.0.Co;2-T  0.434
1977 Fidler IJ, Nicolson GL. Fate of recirculating B16 melanoma metastatic variant cells in parabiotic syngeneic recipients. Journal of the National Cancer Institute. 58: 1867-72. PMID 864765 DOI: 10.1093/Jnci/58.6.1867  0.344
1977 Kripke ML, Budmen MB, Fidler IJ. Production of specific macrophage activating factor by lymphocytes from tumor-bearing mice Cellular Immunology. 30: 341-352. PMID 67910 DOI: 10.1016/0008-8749(77)90077-6  0.437
1977 NICOLSON GL, BRUNSON KW, FIDLER IJ. TUMOR CELL SURFACES: SOME CHARACTERISTICS OF NEOPLASTIC CELLS THAT DETERMINE STATES OF TRANSFORMATION AND MALIGNANCY Acta Histochemica Et Cytochemica. 10: 114-133. DOI: 10.1267/Ahc.10.114  0.459
1976 Fidler IJ. Activation in vitro of mouse macrophages by syngeneic, allogeneic, or xenogeneic lymphocyte supernatants. Journal of the National Cancer Institute. 55: 1159-63. PMID 1206741 DOI: 10.1093/Jnci/55.5.1159  0.425
1976 Fidler IJ, Spitler LE. Effects of levamisole on in vivo and in vitro murine host response to syngeneic transplantable tumor. Journal of the National Cancer Institute. 55: 1107-12. PMID 1206735 DOI: 10.1093/Jnci/55.5.1107  0.446
1976 Fidler IJ, McWilliams RW, Bech-Nielsen S, Budmen MB. Role of the regional lymph node in neoplasia: cellular mediated reactivity in vitro by autologous regional or distant lymph nodes or peripheral blood lymphocytes of dogs with spontaneous neoplasms. Immunological Communications. 4: 325-35. PMID 1184114 DOI: 10.3109/08820137509055783  0.385
1976 Fidler IJ, Caines S, Dolan Z. Survival of hematogenously disseminated allogeneic tumor cells in athymic nude mice. Transplantation. 22: 208-12. PMID 968936 DOI: 10.1097/00007890-197608000-00019  0.314
1976 Fidler IJ, Budmen MB, Hanna MG. Characterization of in vitro reactivity by BCG-treated guinea pigs to syngeneic line-10 hepatocarcinoma Cancer Immunology, Immunotherapy. 1: 179-186. DOI: 10.1007/Bf00205463  0.409
1975 Norbury KC, Fidler IJ. In vitro tumor cell destruction by syngeneic mouse macrophoages: methods for assaying cytotoxicity. Journal of Immunological Methods. 7: 109-22. PMID 1123549 DOI: 10.1016/0022-1759(75)90136-2  0.319
1974 Fidler IJ. The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. European Journal of Cancer. 9: 223-7. PMID 4787857 DOI: 10.1016/S0014-2964(73)80022-2  0.444
1974 Fidler IJ. Immunostimulation-inhibition of tumor cell growth in vitro utilizing tumor target cells labeled with 125I-iodo-deoxyuridine. Immunological Communications. 2: 483-93. PMID 4757433 DOI: 10.3109/08820137309022820  0.426
1973 Fidler IJ. In vitro studies of cellular-mediated immunostimulation of tumor growth. Journal of the National Cancer Institute. 50: 1307-12. PMID 4712593 DOI: 10.1093/Jnci/50.5.1307  0.398
1973 Fidler IJ. Selection of successive tumour lines for metastasis. Nature: New Biology. 242: 148-9. PMID 4512654 DOI: 10.1038/Newbio242148A0  0.384
1973 Fidler IJ, Kahn JM, Montgomery PC. Effect of neuraminidase on the rat one-way mixed lymphocyte interaction. Immunological Communications. 2: 573-83. PMID 4272634 DOI: 10.3109/08820137309022828  0.301
1971 Fidler IJ. Duration of in vivo effects of L-asparaginase on experimental metastasis. Nature. 229: 564-564. PMID 4925355 DOI: 10.1038/229564A0  0.31
1970 Fidler IJ. Metastasis: Quantitative Analysis of Distribution and Fate of Tumor Emboli Labeled With 125I-5-Iodo-2′ -deoxyuridine Journal of the National Cancer Institute. 45: 773-782. DOI: 10.1093/Jnci/45.4.773  0.345
Low-probability matches (unlikely to be authored by this person)
1988 Fidler IJ, Schroit AJ. Recognition and destruction of neoplastic cells by activated macrophages: discrimination of altered self. Biochimica Et Biophysica Acta. 948: 151-73. PMID 3052591 DOI: 10.1016/0304-419X(88)90009-1  0.299
2002 Fan D, Yano S, Shinohara H, Solorzano C, Van Arsdall M, Bucana CD, Pathak S, Kruzel E, Herbst RS, Onn A, Roach JS, Onda M, Wang QC, Pastan I, Fidler IJ. Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin. Molecular Cancer Therapeutics. 1: 595-600. PMID 12479219  0.299
2003 Kuniyasu H, Ohmori H, Sasaki T, Sasahira T, Yoshida K, Kitadai Y, Fidler IJ. Production of interleukin 15 by human colon cancer cells is associated with induction of mucosal hyperplasia, angiogenesis, and metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4802-10. PMID 14581351  0.299
1985 Koff WC, Fidler IJ. The potential use of liposome-mediated antiviral therapy. Antiviral Research. 5: 179-90. PMID 3896138 DOI: 10.1016/0166-3542(85)90050-6  0.299
1993 Dong Z, O'Brian CA, Fidler IJ. Activation of tumoricidal properties in macrophages by lipopolysaccharide requires protein-tyrosine kinase activity Journal of Leukocyte Biology. 53: 53-60. PMID 8426092 DOI: 10.1002/Jlb.53.1.53  0.297
1979 Fogler WE, Gersten DM, Fidler IJ. Inhibition by tertiary amine local anesthetics of phagocytosis in cultured mouse peritoneal macrophages. Biochemical Pharmacology. 27: 2447-53. PMID 569486 DOI: 10.1016/0006-2952(78)90358-1  0.297
2004 Mathew P, Yang J, Kim SJ, Fidler I, Bucana C, Troncoso P, Wang X, Thall P, Logothetis C, Navone N. Inhibition of functional osteoblasts with the platelet-derived growth factor receptor (PDGFR) inhibitor imatinib mesylate in androgen-independent prostate cancer (PCa). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 4625. PMID 28015748 DOI: 10.1200/Jco.2004.22.14_Suppl.4625  0.296
1980 Sone S, Pollack V, Fidler I. Direct activation of tumoricidal properties in rat alveolar macrophages by Nocardia rubra cell wall skeleton Cancer Immunology and Immunotherapy. 9. DOI: 10.1007/Bf00200004  0.295
1989 Fan D, Price J, Schackert H, Seid C, Wilmanns C, Chakrabarty S, Fidler IJ. Antiproliferative activity of liposome-encapsulated transforming growth factor-beta against MDA-MB-435 human breast carcinoma cells. Cancer Communications. 1: 337-43. PMID 2702039 DOI: 10.3727/095535489820875084  0.294
1993 Utsugi T, Brown D, Nii A, Fidler IJ. Frozen-thawed human blood monocytes respond reproducibly to activation stimuli: implications for screening of BRMs. Biotherapy (Dordrecht, Netherlands). 5: 301-8. PMID 1290726 DOI: 10.1007/Bf02179048  0.293
1995 Izumi Y, Taniuchi Y, Tsuji T, Smith CW, Nakamori S, Fidler IJ, Irimura T. Characterization of human colon carcinoma variant cells selected for sialyl Lex carbohydrate antigen: liver colonization and adhesion to vascular endothelial cells. Experimental Cell Research. 216: 215-21. PMID 7529188 DOI: 10.1006/excr.1995.1027  0.289
1986 Saiki I, Bucana CD, Tsao JY, Fidler IJ. Quantitative Fluorescent Microassay for Identification of Antiproliferative Compounds Journal of the National Cancer Institute. 77: 1235-1240. DOI: 10.1093/Jnci/77.6.1235  0.289
1977 Fidler IJ, Peterson DE. In vitro tumor growth inhibition by syngeneic lymphocytes and/or macrophages. Advances in Experimental Medicine and Biology. 389-95. PMID 998402 DOI: 10.1007/978-1-4684-3300-5_33  0.289
2009 Fan D, Kim SJ, Langley RL, Fidler IJ. Metastasis and drug resistance Springer Us. 21-52. DOI: 10.1007/978-0-387-89445-4_2  0.288
1997 Dong Z, Yang X, Fidler IJ. Neutralization of endogenous interferon-beta increases the efficiency of adenoviral vector-mediated gene transduction. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 17: 401-7. PMID 9243372 DOI: 10.1089/Jir.1997.17.401  0.288
2002 Studeny M, Marini FC, Champlin RE, Zompetta C, Fidler IJ, Andreeff M. Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. Cancer Research. 62: 3603-8. PMID 12097260  0.288
2004 Mathew P, Thall PF, Jones D, Perez C, Bucana C, Troncoso P, Kim SJ, Fidler IJ, Logothetis C. Platelet-derived growth factor receptor inhibitor imatinib mesylate and docetaxel: a modular phase I trial in androgen-independent prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 3323-9. PMID 15310776 DOI: 10.1200/Jco.2004.10.116  0.287
1993 Luca M, Hunt B, Bucana CD, Johnson JP, Fidler IJ, Bar-Eli M. Direct correlation between MUC18 expression and metastatic potential of human melanoma cells. Melanoma Research. 3: 35-41. PMID 8471835 DOI: 10.1097/00008390-199304000-00006  0.286
1996 Fidler IJ, Radinsky R. Search for genes that suppress cancer metastasis. Journal of the National Cancer Institute. 88: 1700-3. PMID 8943996 DOI: 10.1093/Jnci/88.23.1700  0.285
1988 Aukerman SL, Fidler IJ. Antigenicity of UV radiation-induced murine tumors correlates positively with the level of adenosine deaminase activity. Cancer Immunology, Immunotherapy : Cii. 25: 175-9. PMID 2824050 DOI: 10.1007/BF00199144  0.285
2004 Bucana CD, Fidler IJ. Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms. International Journal of Oncology. 24: 19-24. PMID 14654936 DOI: 10.3892/Ijo.24.1.19  0.28
1985 Koff WC, Showalter SD, Hampar B, Fidler IJ. Protection of mice against fatal herpes simplex type 2 infection by liposomes containing muramyl tripeptide. Science (New York, N.Y.). 228: 495-7. PMID 2984772 DOI: 10.1126/Science.2984772  0.279
2003 Fidler IJ. Regulation of neoplastic angiogenesis. Journal of the National Cancer Institute. Monographs. 10-4. PMID 11158201 DOI: 10.1093/OXFORDJOURNALS.JNCIMONOGRAPHS.A024251  0.277
1987 Nayar R, Schroit AJ, Fidler IJ. Liposome encapsulation of muramyl peptides for activation of macrophage cytotoxic properties. Methods in Enzymology. 132: 594-603. PMID 3547028 DOI: 10.1016/S0076-6879(86)32044-5  0.277
1996 Dong Z, Yang X, Xie K, Juang SH, Llansa N, Fidler IJ. Activation of inducible nitric oxide synthase gene in murine macrophages requires protein phosphatases 1 and 2A activities. Journal of Leukocyte Biology. 58: 725-32. PMID 7499972 DOI: 10.1002/Jlb.58.6.725  0.277
2001 Fidler IJ. Angiogenic heterogeneity: regulation of neoplastic angiogenesis by the organ microenvironment. Journal of the National Cancer Institute. 93: 1040-1. PMID 11459857 DOI: 10.1093/Jnci/93.14.1040  0.276
1988 Morikawa K, Nayar R, Fidler IJ. In vitro activation of tumoricidal properties in mouse macrophages using the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) incorporated in liposomes. Cancer Immunology, Immunotherapy : Cii. 27: 1-6. PMID 3396025 DOI: 10.1007/Bf00205750  0.276
1996 Killion JJ, Bucana CD, Radinsky R, Dong Z, O'Reilly T, Bilbe G, Tarcsay L, Fidler IJ. Maintenance of intestinal epithelium structural integrity and mucosal leukocytes during chemotherapy by oral administration of muramyl tripeptide phosphatidylethanolamine. Cancer Biotherapy & Radiopharmaceuticals. 11: 363-71. PMID 10851497 DOI: 10.1089/Cbr.1996.11.363  0.273
1991 Fidler IJ. Host and tumour factors in cancer metastasis. European Journal of Clinical Investigation. 20: 481-6. PMID 2124977 DOI: 10.1111/j.1365-2362.1990.tb01889.x  0.273
2003 Onn A, Isobe T, Itasaka S, Wu W, O'Reilly MS, Fidler IJ, Herbst RS. O-290 Blockade of EGFR tyrosine kinase does not predict outcome in a new orthotopic model of human lung cancer Lung Cancer. 41: S84-S85. DOI: 10.1016/S0169-5002(03)91948-9  0.272
1988 Nayar R, Morikawa K, Fidler IJ. Characterization of liposomes containing the chemotactic peptide N-formyl-methionyl-leucyl-phenylalanine (FMLP) and their interaction with mouse macrophages. Cancer Drug Delivery. 4: 233-44. PMID 3454250 DOI: 10.1089/Cdd.1987.4.233  0.272
1983 Kleinerman ES, Schroit AJ, Fogler WE, Fidler IJ. Tumoricidal activity of human monocytes activated in vitro by free and liposome-encapsulated human lymphokines. The Journal of Clinical Investigation. 72: 304-15. PMID 6348087 DOI: 10.1172/Jci110970  0.272
2002 Tedjarati S, Baker CH, Apte S, Huang S, Wolf JK, Killion JJ, Fidler IJ. Synergistic therapy of human ovarian carcinoma implanted orthotopically in nude mice by optimal biological dose of pegylated interferon alpha combined with paclitaxel. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 2413-22. PMID 12114447  0.272
1998 Stearns ME, Ware JL, Agus DB, Chang CJ, Fidler IJ, Fife RS, Goode R, Holmes E, Kinch MS, Peehl DM, Pretlow TG, Thalmann GN. Workgroup 2: human xenograft models of prostate cancer. The Prostate. 36: 56-8. PMID 9650917 DOI: 10.1002/(Sici)1097-0045(19980615)36:1<56::Aid-Pros10>3.0.Co;2-H  0.271
1994 Fan D, Poste G, Seid C, Earnest LE, Bull T, Clyne RK, Fidler IJ. Reversal of multidrug resistance in murine fibrosarcoma cells by thioxanthene flupentixol. Investigational New Drugs. 12: 185-95. PMID 7896537 DOI: 10.1007/Bf00873959  0.266
2003 Solorzano CC, Hwang R, Baker CH, Bucana CD, Pisters PW, Evans DB, Killion JJ, Fidler IJ. Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1858-67. PMID 12738744  0.266
1977 Bech-Nielsen S, Brodey RS, Fidler IJ, Abt DA, Reif JS. The effect of BCG on in vitro immune reactivity and clinical course in dogs treated surgically for osteosarcoma. European Journal of Cancer. 13: 33-41. PMID 321227 DOI: 10.1016/0014-2964(77)90227-4  0.266
1978 Hunter JT, Meltzer MS, Ribi E, Fidler IJ, Hanna MG, Zbar B, Rapp HJ. Glucan: attempts to demonstrate therapeutic activity against five syngeneic tumors in guinea pigs and mice. Journal of the National Cancer Institute. 60: 419-24. PMID 202719 DOI: 10.1093/jnci/60.2.419  0.266
1987 Sella A, Kleinerman E, Von Eschenbach A, Fidler I. Antitumor Activity of Blood Monocytes from Patients with Prostatic Carcinoma Journal of Urology. 137. DOI: 10.1016/S0022-5347(17)75948-4  0.264
1993 Dong Z, Qi X, Fidler IJ. Tyrosine phosphorylation of mitogen-activated protein kinases is necessary for activation of murine macrophages by natural and synthetic bacterial products. The Journal of Experimental Medicine. 177: 1071-7. PMID 8384652 DOI: 10.1084/Jem.177.4.1071  0.262
1988 Hendrix MJ, Seftor EA, Seftor RE, Fidler IJ. A simple quantitative assay for studying the invasive potential of high and low human metastatic variants. Cancer Letters. 38: 137-47. PMID 3690504 DOI: 10.1016/0304-3835(87)90209-6  0.262
2003 Lu W, Su J, Kim LS, Bucana CD, Donawho C, He J, Fidler IJ, Dong Z. Active specific immunotherapy against occult brain metastasis. Cancer Research. 63: 1345-50. PMID 12649197  0.262
1978 Hart IR, Fidler IJ, Hanna MG, Cardy RH, Gutterman JU, Hersh EM. The effects of intravenous administration of Methanol Extraction Residue (MER) of tubercle bacilli in the dog Cancer Immunology, Immunotherapy. 3: 229-238. DOI: 10.1007/Bf00200076  0.26
1999 Kuniyasu H, Troncoso P, Inoue K, Fidler IJ, Dinney CPN, Pettaway CA. Assessment Of Metastasis-Related Gene Expression In Prostate Biopsy Specimens: A Novel Predictor Of Pathologic Stage The Journal of Urology. 237. DOI: 10.1097/00005392-199904010-00949  0.258
1992 Pathak S, Staroselsky AN, Fidler IJ. Specific chromosomal defects associated with metastatic potential in K-1735 melanoma clones. Involvement of chromosomes 4 and 14. Cancer Genetics and Cytogenetics. 56: 209-21. PMID 1756466 DOI: 10.1016/0165-4608(91)90173-R  0.255
1977 Fidler IJ. Depression of macrophages in mice drinking hyperchlorinated water Nature. 270: 735-736. PMID 593395 DOI: 10.1038/270735A0  0.253
1986 Sone S, Lopez-Berestein G, Fidler IJ. Potentiation of direct antitumor cytotoxicity and production of tumor cytolytic factors in human blood monocytes by human recombinant interferon-gamma and muramyl dipeptide derivatives. Cancer Immunology, Immunotherapy : Cii. 21: 93-9. PMID 3081250 DOI: 10.1007/BF00199855  0.252
1989 Denkins Y, Fidler IJ, Kripke ML. Exposure of mice to UV-B radiation suppresses delayed hypersensitivity to Candida albicans Photochemistry and Photobiology. 49: 615-619. PMID 2667002 DOI: 10.1111/J.1751-1097.1989.Tb08432.X  0.251
1987 Fogler WE, Fidler IJ. Comparative interaction of free and liposome-encapsulated nor-muramyl dipeptide or muramyl tripeptide phosphatidylethanolamine (3H-labelled) with human blood monocytes. International Journal of Immunopharmacology. 9: 141-50. PMID 3583507 DOI: 10.1016/0192-0561(87)90088-9  0.25
2005 Yazici M, Busby E, Fidler I, Kim S. 204Blockade of VEGF-R and EGF-R signalling in tumour cells and tumour-associated endothelial cells for therapy of human prostate cancer growing in the bone of nude mice European Urology Supplements. 4: 53. DOI: 10.1016/S1569-9056(05)80212-X  0.25
2003 Hwang RF, Yokoi K, Bucana CD, Tsan R, Killion JJ, Evans DB, Fidler IJ. Inhibition of platelet-derived growth factor receptor phosphorylation by STI571 (Gleevec) reduces growth and metastasis of human pancreatic carcinoma in an orthotopic nude mouse model. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 6534-44. PMID 14695158  0.248
1976 Fidler IJ, Darnell JH. Rat lymphocytes stimulated with insoluble concanavalin-A release mediators which render mouse macrophages nonspecifically tumoricidal☆☆☆ Cellular Immunology. 27: 351. DOI: 10.1016/0008-8749(76)90296-3  0.248
1982 Talmadge JE, Fidler IJ. Cancer metastasis is selective or random depending on the parent tumour population Nature. 297: 593-594. PMID 7088144 DOI: 10.1038/297593a0  0.246
2015 Chen J, Lee HJ, Wu X, Huo L, Kim SJ, Xu L, Wang Y, He J, Bollu LR, Gao G, Su F, Briggs J, Liu X, Melman T, Asara JM, ... Fidler IJ, et al. Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain. Cancer Research. 75: 554-65. PMID 25511375 DOI: 10.1158/0008-5472.Can-14-2268  0.246
2003 Holsinger FC, Doan DD, Jasser SA, Swan EA, Greenberg JS, Schiff BA, Bekele BN, Younes MN, Bucana CD, Fidler IJ, Myers JN. Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 3183-9. PMID 12912971  0.242
2005 Fidler IJ. Blockade of the TGF-beta superfamily by Smad7: breaking a link in the metastatic chain. Journal of the National Cancer Institute. 97: 1714-5. PMID 16333022 DOI: 10.1093/Jnci/Dji437  0.241
1994 Singh RK, Xie K, Gutman M, Berry KK, Bucana CD, Fidler IJ, Bar-Eli M, Huang S. Expression of the JE/MCP-1 gene suppresses metastatic potential in murine colon carcinoma cells Cancer Immunology, Immunotherapy. 39: 231-238. DOI: 10.1007/s002620050119  0.241
1991 Seid CA, Fidler IJ, Clyne RK, Earnest LE, Fan D. Overcoming murine tumor cell resistance to vinblastine by presentation of the drug in multilamellar liposomes consisting of phosphatidylcholine and phosphatidylserine. Selective Cancer Therapeutics. 7: 103-12. PMID 1771296 DOI: 10.1089/sct.1991.7.103  0.24
2005 Hoekstra R, Dumez H, Eskens FA, van der Gaast A, Planting AS, de Heus G, Sizer KC, Ravera C, Vaidyanathan S, Bucana C, Fidler IJ, van Oosterom AT, Verweij J. Phase I and pharmacologic study of PKI166, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 6908-15. PMID 16203782 DOI: 10.1158/1078-0432.Ccr-05-0720  0.239
2012 Fujimaki T, Fan D, Staroselsky A, Gohji K, Bucana C, Fidler I. Critical factors regulating site-specific brain metastasis of murine melanomas. International Journal of Oncology. 3: 789-99. PMID 21573433 DOI: 10.3892/ijo.3.5.789  0.238
1981 Fidler IJ, Raz A, Fogler WE, Poste G. Pulmonary localization of intravenously injected liposomes. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 75: 246-51. PMID 7232836 DOI: 10.1007/978-3-642-81491-4_38  0.236
1997 Singh RK, Fidler IJ. Regulation of tumor angiogenesis by organ-specific cytokines. Current Topics in Microbiology and Immunology. 1-11. PMID 9053286 DOI: 10.1007/978-3-642-61109-4_1  0.236
1996 Roth JA, Beech DJ, Putnam JB, Pollock RE, Patel SR, Fidler IJ, Benjamin RS. Treatment of the patient with lung metastases. Current Problems in Surgery. 33: 881-952. PMID 8909328 DOI: 10.1016/S0011-3840(96)80003-7  0.235
1999 Kitadai Y, Takahashi Y, Haruma K, Naka K, Sumii K, Yokozaki H, Yasui W, Mukaida N, Ohmoto Y, Kajiyama G, Fidler IJ, Tahara E. Transfection of interleukin-8 increases angiogenesis and tumorigenesis of human gastric carcinoma cells in nude mice. British Journal of Cancer. 81: 647-53. PMID 10574250 DOI: 10.1038/sj.bjc.6690742  0.235
2002 Huang SF, Kim SJ, Lee AT, Karashima T, Bucana C, Kedar D, Sweeney P, Mian B, Fan D, Shepherd D, Fidler IJ, Dinney CP, Killion JJ. Inhibition of growth and metastasis of orthotopic human prostate cancer in athymic mice by combination therapy with pegylated interferon-alpha-2b and docetaxel. Cancer Research. 62: 5720-6. PMID 12384530  0.231
1986 Fidler IJ. Optimization and limitations of systemic treatment of murine melanoma metastases with liposomes containing muramyl tripeptide phosphatidylethanolamine. Cancer Immunology, Immunotherapy : Cii. 21: 169-73. PMID 3698058 DOI: 10.1007/BF00199357  0.229
2005 Sclabas GM, Fujioka S, Schmidt C, Li Z, Frederick WA, Yang W, Yokoi K, Evans DB, Abbruzzese JL, Hess KR, Zhang W, Fidler IJ, Chiao PJ. Overexpression of tropomysin-related kinase B in metastatic human pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 440-9. PMID 15701826  0.228
1989 Fidler IJ. Eradication of cancer metastasis by tumoricidal macrophages. Advances in Experimental Medicine and Biology. 233: 415-23. PMID 3223395 DOI: 10.1007/978-1-4899-5037-6_45  0.225
1993 Risin S, Fujimaki T, Mestriner CA, Brown NM, Hopwood VL, Fidler IJ, Pathak S. Clonal expansion of cells with trisomy of chromosomes 12 and X in an EBV-transformed lymphoblastoid cell line and establishment of a tumorigenic monoclonal cell line (48,XX,+X,+12). Cytogenetics and Cell Genetics. 62: 54-5. PMID 8380764 DOI: 10.1159/000133445  0.222
2012 Xie K, Huang S, Dong Z, Fidler I. Cytokine-induced apoptosis in transformed murine fibroblasts involves synthesis of endogenous nitric-oxide. International Journal of Oncology. 3: 1043-8. PMID 21573470 DOI: 10.3892/ijo.3.6.1043  0.221
1993 Bucana CD, Radinsky R, Dong Z, Sanchez R, Brigati DJ, Fidler IJ. A rapid colorimetric in situ mRNA hybridization technique using hyperbiotinylated oligonucleotide probes for analysis of mdr1 in mouse colon carcinoma cells. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 41: 499-506. PMID 8095509 DOI: 10.1177/41.4.8095509  0.219
1992 Fidler IJ. New developments in in vivo models of neoplasia. Cancer Metastasis Reviews. 10: 191-2. PMID 1764763 DOI: 10.1007/Bf00050790  0.218
2002 McGary EC, Weber K, Mills L, Doucet M, Lewis V, Lev DC, Fidler IJ, Bar-Eli M. Inhibition of platelet-derived growth factor-mediated proliferation of osteosarcoma cells by the novel tyrosine kinase inhibitor STI571. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 3584-91. PMID 12429650  0.217
2005 Lev DC, Kim SJ, Onn A, Stone V, Nam DH, Yazici S, Fidler IJ, Price JE. Inhibition of platelet-derived growth factor receptor signaling restricts the growth of human breast cancer in the bone of nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 306-14. PMID 15671560  0.217
1982 Erickson KL, Cicurel L, Gruys E, Fidler IJ. Murine T-cell hybridomas that produce lymphokine with macrophage-activating factor activity as a constitutive product Cellular Immunology. 72: 195-201. PMID 6184172 DOI: 10.1016/0008-8749(82)90297-0  0.215
2004 Chelouche-Lev D, Kim SJ, Fidler IJ, Price JE. Inhibition of platelet derived growth factor receptor restricts the growth of breast cancer cells in the bone but not in the mammary fatpad Annals of Surgical Oncology. 11: S85-S85. DOI: 10.1007/BF02524072  0.215
1988 Ichinose Y, Tsao JY, Fidler IJ. Destruction of tumor cells by monokines released from activated human blood monocytes: evidence for parallel and additive effects of IL-1 and TNF. Cancer Immunology, Immunotherapy : Cii. 27: 7-12. PMID 3260822 DOI: 10.1007/BF00205751  0.211
1989 Fidler IJ. Critical factors regulating the biology of cancer metastasis International Journal of Radiation Oncology*Biology*Physics. 17: 111-112. DOI: 10.1016/0360-3016(89)90629-9  0.206
2008 Fidler IJ. Judah Folkman -- A Personal Tribute Cancer Research. 68: 2548-2548. DOI: 10.1158/0008-5472.Can-08-0671  0.205
1985 Foon KA, Rossio JL, Schroff RW, Wahl SM, Ruscetti FW, Abrams PG, Rager HC, Pickeral SF, Fidler IJ. The generation of stable human T-cell hybridomas which constitutively produce interleukin-2 and chemotactic factor. Hybridoma. 4: 211-22. PMID 3930388 DOI: 10.1089/hyb.1985.4.211  0.203
1990 Fidler IJ. Systemic Activation of Macrophages by Liposomes Containing Muramyltripeptide Phosphatidylethanolamine for therapy of Cancer Metastasis Journal of Liposome Research. 1: 451-461. DOI: 10.3109/08982109009036007  0.202
1992 Fidler IJ. Systemic macrophage activation with liposome-entrapped immunomodulators for therapy of cancer metastasis. Research in Immunology. 143: 199-204. PMID 1574648 DOI: 10.1016/S0923-2494(92)80166-I  0.199
1990 FIDLER IJ. Host and tumour factors in cancer metastasis European Journal of Clinical Investigation. 20: 481-486. DOI: 10.1111/j.1365-2362.1990.tb01914.x  0.197
1995 Fidler IJ. Therapy of cancer metastasis by systemic activation of macrophages. Advances in Pharmacology (San Diego, Calif.). 30: 271-326. PMID 7833294 DOI: 10.1016/S1054-3589(08)60177-5  0.196
2002 Myers JN, Holsinger FC, Jasser SA, Bekele BN, Fidler IJ. An orthotopic nude mouse model of oral tongue squamous cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 293-8. PMID 11801572  0.194
2003 Onn A, Isobe T, Itasaka S, Wu W, O'Reilly MS, Ki Hong W, Fidler IJ, Herbst RS. Development of an orthotopic model to study the biology and therapy of primary human lung cancer in nude mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5532-9. PMID 14654533  0.192
2002 Herrera CA, Xu L, Bucana CD, Silva el VG, Hess KR, Gershenson DM, Fidler IJ. Expression of metastasis-related genes in human epithelial ovarian tumors. International Journal of Oncology. 20: 5-13. PMID 11743636  0.192
1989 Schackert G, Fan D, Nayar R, Fidler IJ. Arrest and retention of multilamellar liposomes in the brain of normal mice or mice bearing experimental brain metastases. Selective Cancer Therapeutics. 5: 73-9. PMID 2772429 DOI: 10.1089/sct.1989.5.73  0.191
1971 Fidler IJ, Montgomery PC, Ferguson E. L-asparaginase and lymphocyte blastogenesis. Lancet (London, England). 2: 1091-2. PMID 4106932 DOI: 10.1016/S0140-6736(71)90407-7  0.19
1982 Talmadge JE, Wolman SR, Fidler IJ. Evidence for the clonal origin of spontaneous metastases Science. 217: 361-363. PMID 6953592 DOI: 10.1126/science.6953592  0.187
1976 Hanna MG, Peters LC, Fidler IJ. The efficacy of BCG-induced tumor immunity in guinea pigs with regional and systemic malignancy Cancer Immunology, Immunotherapy. 1: 171-177. DOI: 10.1007/BF00205462  0.186
1993 Fidler IJ, Kleinerman ES. Therapy of cancer metastasis by systemic activation of macrophages: from the bench to the clinic. Research in Immunology. 144: 284-7; discussion 29. PMID 8378598 DOI: 10.1016/0923-2494(93)80109-C  0.185
2006 Fidler IJ. Antivascular therapy of cancer metastasis. Journal of Surgical Oncology. 94: 178-80. PMID 16900530 DOI: 10.1002/jso.20380  0.185
1985 Schwartz RS, Tanaka Y, Fidler IJ, Chiu DT, Lubin B, Schroit AJ. Increased adherence of sickled and phosphatidylserine-enriched human erythrocytes to cultured human peripheral blood monocytes. The Journal of Clinical Investigation. 75: 1965-72. PMID 4008648 DOI: 10.1172/JCI111913  0.181
1976 Fidler IJ. Letter: Misquotation of article. Journal of the National Cancer Institute. 56: 212-3. PMID 1255757 DOI: 10.1093/Jnci/56.2.212-B  0.177
2005 Mathew P, Fidler I, Bucana C. In Reply: Journal of Clinical Oncology. 23: 1333-1334. DOI: 10.1200/Jco.2005.05.340  0.173
1990 Fidler IJ. Reply to Weiss Clinical & Experimental Metastasis. 8: 107-109. DOI: 10.1007/Bf00155597  0.17
2008 Fidler IJ, Poste G. The "seed and soil" hypothesis revisited. The Lancet. Oncology. 9: 808. PMID 18672217 DOI: 10.1016/S1470-2045(08)70201-8  0.169
1986 Fidler IJ. Intracellular activation of tumoricidal properties in mouse macrophages and human monocytes by recombinant mouse or human gamma interferon encapsulated in liposomes. Annales De L'Institut Pasteur. Immunologie. 212-5. PMID 3089125 DOI: 10.1016/S0771-050X(86)80030-4  0.166
1987 Fidler IJ. Review: biologic heterogeneity of cancer metastases. Breast Cancer Research and Treatment. 9: 17-26. PMID 3297212 DOI: 10.1007/BF01806690  0.156
1988 Fidler IJ. Targeting of immunomodulators to mononuclear phagocytes for therapy of cancer Advanced Drug Delivery Reviews. 2: 69-106. DOI: 10.1016/0169-409X(88)90006-3  0.143
2005 Fidler IJ. Cancer biology is the foundation for therapy. Cancer Biology & Therapy. 4: 1036-9. PMID 16222123  0.142
2003 Fidler IJ. Understanding bone metastases: the key to the effective treatment of prostate cancer. Clinical Advances in Hematology & Oncology : H&O. 1: 278-9. PMID 16224421  0.126
1976 Fidler IJ. Immunologic factors in experimental metastases formation. International Journal of Radiation Oncology, Biology, Physics. 1: 93-6. PMID 1233373 DOI: 10.1016/0360-3016(75)90015-2  0.125
2003 Kuniyasu H, Ukai R, Johnston D, Troncoso P, Fidler IJ, Pettaway CA. The relative mRNA expression levels of matrix metalloproteinase to E-cadherin in prostate biopsy specimens distinguishes organ-confined from advanced prostate cancer at radical prostatectomy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 2185-94. PMID 12796385  0.123
1990 Killion JJ, Fidler IJ. Evasion of host responses in metastasis: implications of cellular resistance to cytokines. Current Opinion in Immunology. 2: 693-6. PMID 2701969 DOI: 10.1016/0952-7915(90)90032-C  0.121
2013 Huang WC, Hsu SC, Huang SJ, Chen YJ, Hsiao YC, Zhang W, Fidler IJ, Hung MC. Exogenous expression of human SGLT1 exhibits aggregations in sodium dodecyl sulfate polyacrylamide gel electrophoresis. American Journal of Translational Research. 5: 441-9. PMID 23724167  0.121
2015 Tefferi A, Kantarjian H, Rajkumar SV, Baker LH, Abkowitz JL, Adamson JW, Advani RH, Allison J, Antman KH, Bast RC, Bennett JM, Benz EJ, Berliner N, Bertino J, Bhatia R, ... ... Fidler IJ, et al. In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. Mayo Clinic Proceedings. 90: 996-1000. PMID 26211600 DOI: 10.1016/j.mayocp.2015.06.001  0.108
1990 Von Eschenbach AC, Avallone A, Price J, Swanson D, Killion J, Stephenson R, Fidler IJ. The biological of renal cancer: The influence of nephrectomy European Urology. 18: 40-41. PMID 2226608 DOI: 10.1159/000463961  0.107
1981 Bingham HG, Hann a, Fidler IJ. Malignant Plastic and Reconstructive Surgery. 67: 710. DOI: 10.1097/00006534-198105000-00100  0.104
2005 Koomen JM, Shih LN, Coombes KR, Li D, Xiao LC, Fidler IJ, Abbruzzese JL, Kobayashi R. Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 1110-8. PMID 15709178  0.098
1986 Ratner S, Schroit AJ, Vinson SB, Fidler IJ. Analogous recognition of phospholipids by insect phagocytes and mammalian macrophages. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 182: 272-6. PMID 3703877 DOI: 10.3181/00379727-182-42339  0.091
1970 Fidler IJ. L-asparaginase and metastasis. Lancet (London, England). 1: 777-8. PMID 4191273 DOI: 10.1016/S0140-6736(70)91003-2  0.078
1982 Fogler W, Brandhorst J, Fidler I. Differentiation between MAF and MIF activities in LK preparations Cellular Immunology. 70: 388. DOI: 10.1016/0008-8749(82)90365-3  0.061
2000 Schackert G, Fidler I. Die Biologie von Hirnmetastasen Der Onkologe. 6: 976-985. DOI: 10.1007/s007610070043  0.056
2004 Fidler IJ. From here to there; a life based on migration. An interview with Isaiah J. Fidler. The International Journal of Developmental Biology. 48: 457-62. PMID 15349820 DOI: 10.1387/ijdb.041790ih  0.054
1968 Koch SA, Fidler IJ. Castro-Intestinal Obstruction by Eyelash Adhesive in a Wooley Monkey (Lagothrix cance) Clinical Pediatrics. 7: 107-108. PMID 4966231 DOI: 10.1177/000992286800700214  0.034
2008 Fidler I. Anti-angiogenic effects of imatinib target smooth muscle cells but not endothelial cells. Angiogenesis. 11: 107; author reply 10. PMID 18256897 DOI: 10.1007/s10456-008-9091-7  0.011
2001 Fidler IJ. Seed and Soil Revisited Surgical Oncology Clinics of North America. 10: 257-270. DOI: 10.1016/S1055-3207(18)30064-4  0.01
1988 Jaehne J, Meyer H-, Wittekind C, Maschek H, Pichlmayr R, Jacobi G, Weiermann G, Vitzthum HG, Schwabe D, Manegold C, Krempien B, Kaufmann M, Bailly M, Doré J-, Fodstad Ø, ... ... Fidler IJ, et al. Late abstracts 186–187 Clinical & Experimental Metastasis. 6: 1-99. DOI: 10.1007/BF01888832  0.01
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