Alain Nepveu - Publications

McGill University, Montreal, QC, Canada 
Cell Biology, Oncology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ramdzan ZM, Vickridge E, Li L, Faraco CCF, Djerir B, Leduy L, Maréchal A, Nepveu A. CUT Domains Stimulate Pol β Enzymatic Activities to Accelerate Completion of Base Excision Repair. Journal of Molecular Biology. 166806. PMID 33450246 DOI: 10.1016/j.jmb.2020.166806  0.4
2017 Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A. CUX1 Stimulates APE1 Enzymatic Activity and Increases the Resistance of Glioblastoma Cells to the Mono-Alkylating Agent, Temozolomide. Neuro-Oncology. PMID 29036362 DOI: 10.1093/Neuonc/Nox178  0.4
2017 Ramdzan ZM, Ginjala V, Pinder JB, Chung D, Donovan CM, Kaur S, Leduy L, Dellaire G, Ganesan S, Nepveu A. The DNA repair function of CUX1 contributes to radioresistance. Oncotarget. PMID 28147323 DOI: 10.18632/Oncotarget.14875  0.4
2016 Kaur S, Coulombe Y, Ramdzan ZM, Leduy L, Masson JY, Nepveu A. SATB1 Functions as an Accessory Factor in Base Excision Repair. The Journal of Biological Chemistry. PMID 27590341 DOI: 10.1074/Jbc.M116.735696  0.4
2015 Pal R, Ramdzan ZM, Kaur S, Duquette PM, Marcotte R, Leduy L, Davoudi S, Lamarche-Vane N, Iulianella A, Nepveu A. CUX2 Protein Functions as an Accessory Factor in the Repair of Oxidative DNA Damage. The Journal of Biological Chemistry. 290: 22520-31. PMID 26221032 DOI: 10.1074/Jbc.M115.651042  0.36
2015 Ramdzan ZM, Pal R, Kaur S, Leduy L, Bérubé G, Davoudi S, Vadnais C, Nepveu A. The function of CUX1 in oxidative DNA damage repair is needed to prevent premature senescence of mouse embryo fibroblasts. Oncotarget. 6: 3613-26. PMID 25682875  0.4
2014 Ramdzan ZM, Vadnais C, Pal R, Vandal G, Cadieux C, Leduy L, Davoudi S, Hulea L, Yao L, Karnezis AN, Paquet M, Dankort D, Nepveu A. RAS transformation requires CUX1-dependent repair of oxidative DNA damage. Plos Biology. 12: e1001807. PMID 24618719 DOI: 10.1371/Journal.Pbio.1001807  0.36
2013 Vadnais C, Awan AA, Harada R, Clermont PL, Leduy L, Bérubé G, Nepveu A. Long-range transcriptional regulation by the p110 CUX1 homeodomain protein on the ENCODE array. Bmc Genomics. 14: 258. PMID 23590133 DOI: 10.1186/1471-2164-14-258  0.56
2012 Vadnais C, Davoudi S, Afshin M, Harada R, Dudley R, Clermont PL, Drobetsky E, Nepveu A. CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage. Nucleic Acids Research. 40: 4483-95. PMID 22319212 DOI: 10.1093/Nar/Gks041  0.36
2011 Sansregret L, Vadnais C, Livingstone J, Kwiatkowski N, Awan A, Cadieux C, Leduy L, Hallett MT, Nepveu A. Cut homeobox 1 causes chromosomal instability by promoting bipolar division after cytokinesis failure. Proceedings of the National Academy of Sciences of the United States of America. 108: 1949-54. PMID 21245318 DOI: 10.1073/Pnas.1008403108  0.4
2010 Sansregret L, Gallo D, Santaguida M, Leduy L, Harada R, Nepveu A. Hyperphosphorylation by cyclin B/CDK1 in mitosis resets CUX1 DNA binding clock at each cell cycle. The Journal of Biological Chemistry. 285: 32834-43. PMID 20729212 DOI: 10.1074/Jbc.M110.156406  0.56
2009 Cadieux C, Kedinger V, Yao L, Vadnais C, Drossos M, Paquet M, Nepveu A. Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types. Cancer Research. 69: 7188-97. PMID 19738070 DOI: 10.1158/0008-5472.Can-08-4899  0.36
2009 Kedinger V, Sansregret L, Harada R, Vadnais C, Cadieux C, Fathers K, Park M, Nepveu A. p110 CUX1 homeodomain protein stimulates cell migration and invasion in part through a regulatory cascade culminating in the repression of E-cadherin and occludin. The Journal of Biological Chemistry. 284: 27701-11. PMID 19635798 DOI: 10.1074/Jbc.M109.031849  0.36
2009 Wilson BJ, Harada R, LeDuy L, Hollenberg MD, Nepveu A. CUX1 transcription factor is a downstream effector of the proteinase-activated receptor 2 (PAR2). The Journal of Biological Chemistry. 284: 36-45. PMID 18952606 DOI: 10.1074/Jbc.M803808200  0.36
2008 Goulet B, Markovic Y, Leduy L, Nepveu A. Proteolytic processing of cut homeobox 1 by neutrophil elastase in the MV4;11 myeloid leukemia cell line. Molecular Cancer Research : McR. 6: 644-53. PMID 18403643 DOI: 10.1158/1541-7786.Mcr-07-0268  0.4
2008 Cadieux C, Harada R, Paquet M, Côté O, Trudel M, Nepveu A, Bouchard M. Polycystic kidneys caused by sustained expression of Cux1 isoform p75. The Journal of Biological Chemistry. 283: 13817-24. PMID 18356167 DOI: 10.1074/Jbc.M709332200  0.36
2008 Truscott M, Harada R, Vadnais C, Robert F, Nepveu A. p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes. Molecular and Cellular Biology. 28: 3127-38. PMID 18347061 DOI: 10.1128/Mcb.02089-07  0.4
2008 Harada R, Vadnais C, Sansregret L, Leduy L, Bérubé G, Robert F, Nepveu A. Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes. Nucleic Acids Research. 36: 189-202. PMID 18003658 DOI: 10.1093/Nar/Gkm970  0.56
2007 Goulet B, Sansregret L, Leduy L, Bogyo M, Weber E, Chauhan SS, Nepveu A. Increased expression and activity of nuclear cathepsin L in cancer cells suggests a novel mechanism of cell transformation. Molecular Cancer Research : McR. 5: 899-907. PMID 17855659 DOI: 10.1158/1541-7786.Mcr-07-0160  0.4
2007 Truscott M, Denault JB, Goulet B, Leduy L, Salvesen GS, Nepveu A. Carboxyl-terminal proteolytic processing of CUX1 by a caspase enables transcriptional activation in proliferating cells. The Journal of Biological Chemistry. 282: 30216-26. PMID 17681953 DOI: 10.1074/Jbc.M702328200  0.36
2006 Goulet B, Truscott M, Nepveu A. A novel proteolytically processed CDP/Cux isoform of 90 kDa is generated by cathepsin L. Biological Chemistry. 387: 1285-93. PMID 16972798 DOI: 10.1515/Bc.2006.159  0.4
2006 Sansregret L, Goulet B, Harada R, Wilson B, Leduy L, Bertoglio J, Nepveu A. The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase. Molecular and Cellular Biology. 26: 2441-55. PMID 16508018 DOI: 10.1128/Mcb.26.6.2441-2455.2006  0.4
2005 Santaguida M, Nepveu A. Differential regulation of CDP/Cux p110 by cyclin A/Cdk2 and cyclin A/Cdk1. The Journal of Biological Chemistry. 280: 32712-21. PMID 16081423 DOI: 10.1074/Jbc.M505417200  0.56
2005 Gingras H, Cases O, Krasilnikova M, Bérubé G, Nepveu A. Biochemical characterization of the mammalian Cux2 protein. Gene. 344: 273-85. PMID 15656993 DOI: 10.1016/J.Gene.2004.11.008  0.56
2004 Truscott M, Raynal L, Wang Y, Bérubé G, Leduy L, Nepveu A. The N-terminal region of the CCAAT displacement protein (CDP)/Cux transcription factor functions as an autoinhibitory domain that modulates DNA binding. The Journal of Biological Chemistry. 279: 49787-94. PMID 15377665 DOI: 10.1074/Jbc.M409484200  0.56
2004 Goulet B, Baruch A, Moon NS, Poirier M, Sansregret LL, Erickson A, Bogyo M, Nepveu A. A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor. Molecular Cell. 14: 207-19. PMID 15099520 DOI: 10.1016/S1097-2765(04)00209-6  0.56
2003 Erturk E, Ostapchuk P, Wells SI, Yang J, Gregg K, Nepveu A, Dudley JP, Hearing P. Binding of CCAAT displacement protein CDP to adenovirus packaging sequences. Journal of Virology. 77: 6255-64. PMID 12743282 DOI: 10.1128/Jvi.77.11.6255-6264.2003  0.36
2003 Truscott M, Raynal L, Premdas P, Goulet B, Leduy L, Bérubé G, Nepveu A. CDP/Cux stimulates transcription from the DNA polymerase alpha gene promoter. Molecular and Cellular Biology. 23: 3013-28. PMID 12665598 DOI: 10.1128/Mcb.23.8.3013-3028.2003  0.56
2002 Goulet B, Watson P, Poirier M, Leduy L, Bérubé G, Meterissian S, Jolicoeur P, Nepveu A. Characterization of a tissue-specific CDP/Cux isoform, p75, activated in breast tumor cells. Cancer Research. 62: 6625-33. PMID 12438259  0.36
2002 Moon NS, Rong Zeng W, Premdas P, Santaguida M, Bérubé G, Nepveu A. Expression of N-terminally truncated isoforms of CDP/CUX is increased in human uterine leiomyomas. International Journal of Cancer. 100: 429-32. PMID 12115525 DOI: 10.1002/Ijc.10510  0.56
2001 Santaguida M, Ding Q, Bérubé G, Truscott M, Whyte P, Nepveu A. Phosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2). The Journal of Biological Chemistry. 276: 45780-90. PMID 11584018 DOI: 10.1074/jbc.M107978200  0.56
2001 Moon NS, Premdas P, Truscott M, Leduy L, Bérubé G, Nepveu A. S phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain protein. Molecular and Cellular Biology. 21: 6332-45. PMID 11509674 DOI: 10.1128/Mcb.21.18.6332-6345.2001  0.56
2001 Nirodi C, Hart J, Dhawan P, Moon NS, Nepveu A, Richmond A. The role of CDP in the negative regulation of CXCL1 gene expression. The Journal of Biological Chemistry. 276: 26122-31. PMID 11371564 DOI: 10.1074/Jbc.M102872200  0.56
2000 Moon NS, Bérubé G, Nepveu A. CCAAT displacement activity involves CUT repeats 1 and 2, not the CUT homeodomain. The Journal of Biological Chemistry. 275: 31325-34. PMID 10864926 DOI: 10.1074/Jbc.M002912200  0.36
2000 Martin-Soudant N, Drachman JG, Kaushansky K, Nepveu A. CDP/Cut DNA binding activity is down-modulated in granulocytes, macrophages and erythrocytes but remains elevated in differentiating megakaryocytes Leukemia. 14: 863-873. PMID 10803519 DOI: 10.1038/Sj.Leu.2401764  0.36
2000 Rong Zeng W, Soucie E, Sung Moon N, Martin-Soudant N, Bérubé G, Leduy L, Nepveu A. Exon/intron structure and alternative transcripts of the CUTL1 gene. Gene. 241: 75-85. PMID 10607901 DOI: 10.1016/S0378-1119(99)00465-5  0.56
1999 Jackson RJ, Antonia SJ, Wright KL, Moon NS, Nepveu A, Muñoz-Antonia T. Human cut-like repressor protein binds TGFbeta type II receptor gene promoter. Archives of Biochemistry and Biophysics. 371: 290-300. PMID 10545217 DOI: 10.1006/Abbi.1999.1459  0.36
1999 Wee C, Muise ES, Coquelet O, Ennis M, Wagner J, Lemieux N, Branton PE, Nepveu A, Tremblay ML. Promoter analysis of the murine T-cell protein tyrosine phosphatase gene Gene. 237: 351-360. PMID 10521659 DOI: 10.1016/S0378-1119(99)00332-7  0.36
1998 Coqueret O, Bérubé G, Nepveu A. The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase. The Embo Journal. 17: 4680-94. PMID 9707427 DOI: 10.1093/Emboj/17.16.4680  0.56
1998 Webster MA, Martin-Soudant N, Nepveu A, Cardiff RD, Muller WJ. The induction of uterine leiomyomas and mammary tumors in transgenic mice expressing polyomavirus (PyV) large T (LT) antigen is associated with the ability of PyV LT antigen to form specific complexes with retinoblastoma and CUTL1 family members. Oncogene. 16: 1963-72. PMID 9591780 DOI: 10.1038/Sj.Onc.1201707  0.36
1998 Coqueret O, Martin N, Bérubé G, Rabbat M, Litchfield DW, Nepveu A. DNA binding by cut homeodomain proteins is down-modulated by casein kinase II. The Journal of Biological Chemistry. 273: 2561-6. PMID 9446557 DOI: 10.1074/jbc.273.5.2561  0.56
1996 Mailly F, Bérubé G, Harada R, Mao PL, Phillips S, Nepveu A. The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy. Molecular and Cellular Biology. 16: 5346-57. PMID 8816446 DOI: 10.1128/Mcb.16.10.5346  0.56
1996 Coqueret O, Bérubé G, Nepveu A. DNA binding by cut homeodomain proteins is down-modulated by protein kinase C. The Journal of Biological Chemistry. 271: 24862-8. PMID 8798762 DOI: 10.1074/Jbc.271.40.24862  0.56
1995 Harada R, Bérubé G, Tamplin OJ, Denis-Larose C, Nepveu A. DNA-binding specificity of the cut repeats from the human cut-like protein. Molecular and Cellular Biology. 15: 129-40. PMID 7799919 DOI: 10.1128/Mcb.15.1.129  0.56
1987 Sasarman A, Nepveu A, Echelard Y, Dymetryszyn J, Drolet M, Goyer C. Molecular cloning and sequencing of the hemD gene of Escherichia coli K-12 and preliminary data on the Uro operon Journal of Bacteriology. 169: 4257-4262. PMID 3040684 DOI: 10.1128/Jb.169.9.4257-4262.1987  0.36
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