Lawrence Pfeffer - Publications

Affiliations: 
University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pathology, Cell Biology, Molecular Biology

50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ponnusamy S, He Y, Hwang DJ, Thiyagarajan T, Houtman R, Bocharova V, Sumpter BG, Fernandez E, Johnson DL, DU Z, Pfeffer LM, Getzenberg RH, McEwan IJ, Miller DD, Narayanan R. Orally-Bioavailable Androgen Receptor Degrader, A Potential Next-Generation Therapeutic for Enzalutamide-Resistant Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31481513 DOI: 10.1158/1078-0432.CCR-19-1458  0.32
2017 Du Z, Cai C, Sims M, Boop FA, Davidoff AM, Pfeffer LM. The effects of type I interferon on glioblastoma cancer stem cells. Biochemical and Biophysical Research Communications. PMID 28728846 DOI: 10.1016/j.bbrc.2017.07.098  0.32
2017 Pfeffer SR, Fan M, Du Z, Yang CH, Pfeffer LM. Unphosphorylated STAT3 regulates the antiproliferative, antiviral, and gene-inducing actions of type I interferons. Biochemical and Biophysical Research Communications. PMID 28642132 DOI: 10.1016/j.bbrc.2017.06.111  0.32
2017 Wang B, Shen A, Ouyang X, Zhao G, Du Z, Huo W, Zhang T, Wang Y, Yang C, Dong P, Watari H, Pfeffer LM, Yue J. KLF4 expression enhances the efficacy of chemotherapy drugs in ovarian cancer cells. Biochemical and Biophysical Research Communications. PMID 28108288 DOI: 10.1016/j.bbrc.2017.01.062  0.32
2016 Sethuraman A, Brown M, Seagroves TN, Wu ZH, Pfeffer LM, Fan M. SMARCE1 regulates metastatic potential of breast cancer cells through the HIF1A/PTK2 pathway. Breast Cancer Research : Bcr. 18: 81. PMID 27495308 DOI: 10.1186/s13058-016-0738-9  0.32
2016 Wang R, Davidoff AM, Pfeffer LM. Bortezomib sensitizes human glioblastoma cells to induction of apoptosis by type I interferons through NOXA expression and Mcl-1 cleavage. Biochemical and Biophysical Research Communications. PMID 27450810 DOI: 10.1016/j.bbrc.2016.07.080  0.32
2015 Zhao G, Guo Y, Chen Z, Wang Y, Yang C, Dudas A, Du Z, Liu W, Zou Y, Szabo E, Lee SC, Sims M, Gu W, Tillmanns T, Pfeffer LM, et al. miR-203 Functions as a Tumor Suppressor by Inhibiting Epithelial to Mesenchymal Transition in Ovarian Cancer. Journal of Cancer Science & Therapy. 7: 34-43. PMID 26819680 DOI: 10.4172/1948-5956.1000322  0.32
2015 Garner JM, Ellison DW, Finkelstein D, Ganguly D, Du Z, Sims M, Yang CH, Interiano RB, Davidoff AM, Pfeffer LM. Correction: Molecular Heterogeneity in a Patient-Derived Glioblastoma Xenoline Is Regulated by Different Cancer Stem Cell Populations. Plos One. 10: e0145052. PMID 26660737 DOI: 10.1371/journal.pone.0145052  0.32
2015 Yang CH, Li K, Pfeffer SR, Pfeffer LM. The Type I IFN-Induced miRNA, miR-21. Pharmaceuticals (Basel, Switzerland). 8: 836-847. PMID 26610525 DOI: 10.3390/ph8040836  0.32
2015 Banerjee S, Wang J, Pfeffer S, Ma D, Pfeffer LM, Patil SA, Li W, Miller DD. Design, Synthesis and Biological Evaluation of Novel 5H-Chromenopyridines as Potential Anti-Cancer Agents. Molecules (Basel, Switzerland). 20: 17152-17165. PMID 26393554 DOI: 10.3390/molecules200917152  0.32
2015 Pfeffer SR, Yang CH, Pfeffer LM. The Role of miR-21 in Cancer. Drug Development Research. PMID 26082192 DOI: 10.1002/ddr.21257  0.32
2015 Niu J, Xue A, Chi Y, Xue J, Wang W, Zhao Z, Fan M, Yang CH, Shao ZM, Pfeffer LM, Wu J, Wu ZH. Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer. Oncogene. PMID 26028030 DOI: 10.1038/onc.2015.189  0.32
2015 Garner JM, Ellison DW, Finkelstein D, Ganguly D, Du Z, Sims M, Yang CH, Interiano RB, Davidoff AM, Pfeffer LM. Molecular heterogeneity in a patient-derived glioblastoma xenoline is regulated by different cancer stem cell populations. Plos One. 10: e0125838. PMID 25955030 DOI: 10.1371/journal.pone.0125838  0.32
2015 Guo Y, Tian P, Yang C, Liang Z, Li M, Sims M, Lu L, Zhang Z, Li H, Pfeffer LM, Yue J. Silencing the double-stranded RNA binding protein DGCR8 inhibits ovarian cancer cell proliferation, migration, and invasion. Pharmaceutical Research. 32: 769-78. PMID 25823356 DOI: 10.1007/s11095-013-1219-9  0.32
2015 Yang CH, Pfeffer SR, Sims M, Yue J, Wang Y, Linga VG, Paulus E, Davidoff AM, Pfeffer LM. The oncogenic microRNA-21 inhibits the tumor suppressive activity of FBXO11 to promote tumorigenesis. The Journal of Biological Chemistry. 290: 6037-46. PMID 25589783 DOI: 10.1074/jbc.M114.632125  0.32
2014 Pfeffer LM, Li K, Fleckenstein JF, Marion TN, Diament J, Yang CH, Pfeffer SR, Fan M, Handorf E, Handorf CR. An interferon response gene signature is associated with the therapeutic response of hepatitis C patients. Plos One. 9: e104202. PMID 25111807 DOI: 10.1371/journal.pone.0104202  0.32
2014 Krutilina R, Sun W, Sethuraman A, Brown M, Seagroves TN, Pfeffer LM, Ignatova T, Fan M. MicroRNA-18a inhibits hypoxia-inducible factor 1α activity and lung metastasis in basal breast cancers. Breast Cancer Research : Bcr. 16: R78. PMID 25069832 DOI: 10.1186/bcr3693  0.32
2014 Yang CH, Yue J, Pfeffer SR, Fan M, Paulus E, Hosni-Ahmed A, Sims M, Qayyum S, Davidoff AM, Handorf CR, Pfeffer LM. MicroRNA-21 promotes glioblastoma tumorigenesis by down-regulating insulin-like growth factor-binding protein-3 (IGFBP3). The Journal of Biological Chemistry. 289: 25079-87. PMID 25059666 DOI: 10.1074/jbc.M114.593863  0.32
2014 Fan M, Sethuraman A, Brown M, Sun W, Pfeffer LM. Systematic analysis of metastasis-associated genes identifies miR-17-5p as a metastatic suppressor of basal-like breast cancer. Breast Cancer Research and Treatment. 146: 487-502. PMID 25001613 DOI: 10.1007/s10549-014-3040-5  0.32
2014 Quackenbush JF, Cassidy PB, Pfeffer LM, Boucher KM, Hawkes JE, Pfeffer SR, Kopelovich L, Leachman SA. Isolation of circulating microRNAs from microvesicles found in human plasma. Methods in Molecular Biology (Clifton, N.J.). 1102: 641-53. PMID 24259003 DOI: 10.1007/978-1-62703-727-3_34  0.32
2013 Fan M, Krutilina R, Sun J, Sethuraman A, Yang CH, Wu ZH, Yue J, Pfeffer LM. Comprehensive analysis of microRNA (miRNA) targets in breast cancer cells. The Journal of Biological Chemistry. 288: 27480-93. PMID 23921383 DOI: 10.1074/jbc.M113.491803  0.32
2013 Garner JM, Fan M, Yang CH, Du Z, Sims M, Davidoff AM, Pfeffer LM. Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor κB signaling in glioblastoma cancer stem cells regulates the Notch pathway. The Journal of Biological Chemistry. 288: 26167-76. PMID 23902772 DOI: 10.1074/jbc.M113.477950  0.32
2013 Patil SA, Hosni-Ahmed A, Jones TS, Patil R, Pfeffer LM, Miller DD. Novel approaches to glioma drug design and drug screening. Expert Opinion On Drug Discovery. 8: 1135-51. PMID 23738794 DOI: 10.1517/17460441.2013.807248  0.32
2013 Orr WS, Denbo JW, Saab KR, Ng CY, Wu J, Li K, Garner JM, Morton CL, Du Z, Pfeffer LM, Davidoff AM. Curcumin potentiates rhabdomyosarcoma radiosensitivity by suppressing NF-κB activity. Plos One. 8: e51309. PMID 23408929 DOI: 10.1371/journal.pone.0051309  0.32
2013 Fan M, Pfeffer SR, Lynch HT, Cassidy P, Leachman S, Pfeffer LM, Kopelovich L. Altered transcriptome signature of phenotypically normal skin fibroblasts heterozygous for CDKN2A in familial melanoma: relevance to early intervention. Oncotarget. 4: 128-41. PMID 23371019  0.32
2012 Chen H, Fan M, Pfeffer LM, Laribee RN. The histone H3 lysine 56 acetylation pathway is regulated by target of rapamycin (TOR) signaling and functions directly in ribosomal RNA biogenesis. Nucleic Acids Research. 40: 6534-46. PMID 22553361 DOI: 10.1093/nar/gks345  0.32
2012 Du Z, Whitt MA, Baumann J, Garner JM, Morton CL, Davidoff AM, Pfeffer LM. Inhibition of type I interferon-mediated antiviral action in human glioma cells by the IKK inhibitors BMS-345541 and TPCA-1. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 32: 368-77. PMID 22509977 DOI: 10.1089/jir.2012.0002  0.32
2012 Orr WS, Denbo JW, Saab KR, Myers AL, Ng CY, Zhou J, Morton CL, Pfeffer LM, Davidoff AM. Liposome-encapsulated curcumin suppresses neuroblastoma growth through nuclear factor-kappa B inhibition. Surgery. 151: 736-44. PMID 22284765 DOI: 10.1016/j.surg.2011.12.014  0.32
2012 Li K, Li NL, Wei D, Pfeffer SR, Fan M, Pfeffer LM. Activation of chemokine and inflammatory cytokine response in hepatitis C virus-infected hepatocytes depends on Toll-like receptor 3 sensing of hepatitis C virus double-stranded RNA intermediates. Hepatology (Baltimore, Md.). 55: 666-75. PMID 22030901 DOI: 10.1002/hep.24763  0.32
2011 Yang CH, Yue J, Pfeffer SR, Handorf CR, Pfeffer LM. MicroRNA miR-21 regulates the metastatic behavior of B16 melanoma cells. The Journal of Biological Chemistry. 286: 39172-8. PMID 21940630 DOI: 10.1074/jbc.M111.285098  0.32
2011 Denbo JW, Williams RF, Orr WS, Sims TL, Ng CY, Zhou J, Spence Y, Morton CL, Nathwani AC, Duntsch C, Pfeffer LM, Davidoff AM. Continuous local delivery of interferon-β stabilizes tumor vasculature in an orthotopic glioblastoma xenograft resection model. Surgery. 150: 497-504. PMID 21878236 DOI: 10.1016/j.surg.2011.07.044  0.32
2011 Rosebush MS, Rao SK, Samant S, Gu W, Handorf CR, Pfeffer LM, Nosrat CA. Oral cancer: enduring characteristics and emerging trends. The Journal of the Tennessee Dental Association. 91: 24-7; quiz 28-9. PMID 21748976  0.32
2010 Rao SK, Pavicevic Z, Du Z, Kim JG, Fan M, Jiao Y, Rosebush M, Samant S, Gu W, Pfeffer LM, Nosrat CA. Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. The Journal of Biological Chemistry. 285: 32512-21. PMID 20702412 DOI: 10.1074/jbc.M110.150490  0.32
2010 Narayanan D, Xi Q, Pfeffer LM, Jaggar JH. Mitochondria control functional CaV1.2 expression in smooth muscle cells of cerebral arteries. Circulation Research. 107: 631-41. PMID 20616314 DOI: 10.1161/CIRCRESAHA.110.224345  0.32
2010 Wang N, Dong Q, Li J, Jangra RK, Fan M, Brasier AR, Lemon SM, Pfeffer LM, Li K. Viral induction of the zinc finger antiviral protein is IRF3-dependent but NF-kappaB-independent. The Journal of Biological Chemistry. 285: 6080-90. PMID 20048147 DOI: 10.1074/jbc.M109.054486  0.32
2009 Du Z, Fan M, Kim JG, Eckerle D, Lothstein L, Wei L, Pfeffer LM. Interferon-resistant Daudi cell line with a Stat2 defect is resistant to apoptosis induced by chemotherapeutic agents. The Journal of Biological Chemistry. 284: 27808-15. PMID 19687011 DOI: 10.1074/jbc.M109.028324  0.32
2008 Rosati SF, Williams RF, Nunnally LC, McGee MC, Sims TL, Tracey L, Zhou J, Fan M, Ng CY, Nathwani AC, Stewart CF, Pfeffer LM, Davidoff AM. IFN-beta sensitizes neuroblastoma to the antitumor activity of temozolomide by modulating O6-methylguanine DNA methyltransferase expression. Molecular Cancer Therapeutics. 7: 3852-8. PMID 19056675 DOI: 10.1158/1535-7163.MCT-08-0806  0.32
2008 Wei L, Fan M, Xu L, Heinrich K, Berry MW, Homayouni R, Pfeffer LM. Bioinformatic analysis reveals cRel as a regulator of a subset of interferon-stimulated genes. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 28: 541-51. PMID 18715197 DOI: 10.1089/jir.2007.0136  0.32
2008 Yang CH, Murti A, Pfeffer SR, Fan M, Du Z, Pfeffer LM. The role of TRAF2 binding to the type I interferon receptor in alternative NF kappaB activation and antiviral response. The Journal of Biological Chemistry. 283: 14309-16. PMID 18362156 DOI: 10.1074/jbc.M708895200  0.32
2007 Du Z, Wei L, Murti A, Pfeffer SR, Fan M, Yang CH, Pfeffer LM. Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway. Journal of Cellular Biochemistry. 102: 1087-94. PMID 17910035 DOI: 10.1002/jcb.21535  0.32
2007 Gharavi NM, Alva JA, Mouillesseaux KP, Lai C, Yeh M, Yeung W, Johnson J, Szeto WL, Hong L, Fishbein M, Wei L, Pfeffer LM, Berliner JA. Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo. The Journal of Biological Chemistry. 282: 31460-8. PMID 17726017 DOI: 10.1074/jbc.M704267200  0.32
2007 Dickson PV, Hamner JB, Streck CJ, Ng CY, McCarville MB, Calabrese C, Gilbertson RJ, Stewart CF, Wilson CM, Gaber MW, Pfeffer LM, Skapek SX, Nathwani AC, Davidoff AM. Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature. Molecular Cancer Research : McR. 5: 531-42. PMID 17579115 DOI: 10.1158/1541-7786.MCR-06-0259  0.32
2007 Yang CH, Wei L, Pfeffer SR, Du Z, Murti A, Valentine WJ, Zheng Y, Pfeffer LM. Identification of CXCL11 as a STAT3-dependent gene induced by IFN. Journal of Immunology (Baltimore, Md. : 1950). 178: 986-92. PMID 17202361  0.32
2006 He XS, Ji X, Hale MB, Cheung R, Ahmed A, Guo Y, Nolan GP, Pfeffer LM, Wright TL, Risch N, Tibshirani R, Greenberg HB. Global transcriptional response to interferon is a determinant of HCV treatment outcome and is modified by race. Hepatology (Baltimore, Md.). 44: 352-9. PMID 16871572 DOI: 10.1002/hep.21267  0.32
2006 Bao L, Wei L, Peirce JL, Homayouni R, Li H, Zhou M, Chen H, Lu L, Williams RW, Pfeffer LM, Goldowitz D, Cui Y. Combining gene expression QTL mapping and phenotypic spectrum analysis to uncover gene regulatory relationships. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 575-83. PMID 16783639 DOI: 10.1007/s00335-005-0172-2  0.32
2006 Wei L, Sandbulte MR, Thomas PG, Webby RJ, Homayouni R, Pfeffer LM. NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity. The Journal of Biological Chemistry. 281: 11678-84. PMID 16517601 DOI: 10.1074/jbc.M513286200  0.32
2005 Yang CH, Murti A, Valentine WJ, Du Z, Pfeffer LM. Interferon alpha activates NF-kappaB in JAK1-deficient cells through a TYK2-dependent pathway. The Journal of Biological Chemistry. 280: 25849-53. PMID 15883164 DOI: 10.1074/jbc.M413721200  0.32
2004 Duntsch CD, Zhou Q, Jayakar HR, Weimar JD, Robertson JH, Pfeffer LM, Wang L, Xiang Z, Whitt MA. Recombinant vesicular stomatitis virus vectors as oncolytic agents in the treatment of high-grade gliomas in an organotypic brain tissue slice-glioma coculture model. Journal of Neurosurgery. 100: 1049-59. PMID 15200120 DOI: 10.3171/jns.2004.100.6.1049  0.32
2004 Pfeffer LM, Kim JG, Pfeffer SR, Carrigan DJ, Baker DP, Wei L, Homayouni R. Role of nuclear factor-kappaB in the antiviral action of interferon and interferon-regulated gene expression. The Journal of Biological Chemistry. 279: 31304-11. PMID 15131130 DOI: 10.1074/jbc.M308975200  0.32
2004 Miller MA, Lavine CL, Klas SD, Pfeffer LM, Whitt MA. Recombinant replication-restricted VSV as an expression vector for murine cytokines. Protein Expression and Purification. 33: 92-103. PMID 14680966 DOI: 10.1016/j.pep.2003.08.008  0.32
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