| Year |
Citation |
Score |
| 2020 |
Wang Y, Luo W, Han J, Khan ZA, Fang Q, Jin Y, Chen X, Zhang Y, Wang M, Qian J, Huang W, Lum H, Wu G, Liang G. MD2 activation by direct AGE interaction drives inflammatory diabetic cardiomyopathy. Nature Communications. 11: 2148. PMID 32358497 DOI: 10.1038/S41467-020-15978-3 |
0.302 |
|
| 2019 |
Chen H, Zhang Y, Zhang W, Liu H, Sun C, Zhang B, Bai B, Wu D, Xiao Z, Lum H, Zhou J, Chen R, Liang G. Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 63: 152997. PMID 31254764 DOI: 10.1016/J.Phymed.2019.152997 |
0.325 |
|
| 2019 |
Xu S, Luo W, Xu X, Qian Y, Xu Z, Yu W, Shan X, Guan X, Lum H, Zhou H, Wang Y. MD2 blockade prevents oxLDL-induced renal epithelial cell injury and protects against high-fat-diet-induced kidney dysfunction. The Journal of Nutritional Biochemistry. 70: 47-55. PMID 31151053 DOI: 10.1016/J.Jnutbio.2019.04.003 |
0.329 |
|
| 2018 |
Zhang Y, Liu Z, Wu J, Bai B, Chen H, Xiao Z, Chen L, Zhao Y, Lum H, Wang Y, Zhang H, Liang G. New MD2 inhibitors derived from curcumin with improved anti-inflammatory activity. European Journal of Medicinal Chemistry. 148: 291-305. PMID 29466778 DOI: 10.1016/J.Ejmech.2018.02.008 |
0.349 |
|
| 2017 |
Xu Z, Li W, Han J, Zou C, Huang W, Yu W, Shan X, Lum H, Li X, Liang G. Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2). Scientific Reports. 7: 44911. PMID 28322341 DOI: 10.1038/Srep44911 |
0.335 |
|
| 2014 |
Cowan C, Muraleedharan CK, O'Donnell JJ, Singh PK, Lum H, Kumar A, Xu S. MicroRNA-146 inhibits thrombin-induced NF-κB activation and subsequent inflammatory responses in human retinal endothelial cells. Investigative Ophthalmology & Visual Science. 55: 4944-51. PMID 24985472 DOI: 10.1167/Iovs.13-13631 |
0.39 |
|
| 2014 |
Zhuge Y, Yuan Y, van Breemen R, Degrand M, Holian O, Yoder M, Lum H. Stimulated bronchial epithelial cells release bioactive lysophosphatidylcholine 16:0, 18:0, and 18:1. Allergy, Asthma & Immunology Research. 6: 66-74. PMID 24404396 DOI: 10.4168/Aair.2014.6.1.66 |
0.315 |
|
| 2012 |
Si H, Yu J, Jiang H, Lum H, Liu D. Phytoestrogen genistein up-regulates endothelial nitric oxide synthase expression via activation of cAMP response element-binding protein in human aortic endothelial cells. Endocrinology. 153: 3190-8. PMID 22669896 DOI: 10.1210/En.2012-1076 |
0.529 |
|
| 2011 |
O'Donnell JJ, Zhuge Y, Holian O, Cheng F, Thomas LL, Forsyth CB, Lum H. Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. Microvascular Research. 82: 105-12. PMID 21554891 DOI: 10.1016/J.Mvr.2011.04.008 |
0.504 |
|
| 2011 |
Rao G, Ding HG, Huang W, Le D, Maxhimer JB, Oosterhof A, van Kuppevelt T, Lum H, Lewis EJ, Reddy V, Prinz RA, Xu X. Reactive oxygen species mediate high glucose-induced heparanase-1 production and heparan sulphate proteoglycan degradation in human and rat endothelial cells: a potential role in the pathogenesis of atherosclerosis. Diabetologia. 54: 1527-38. PMID 21424539 DOI: 10.1007/S00125-011-2110-Z |
0.39 |
|
| 2010 |
Fu Z, Zhang W, Zhen W, Lum H, Nadler J, Bassaganya-Riera J, Jia Z, Wang Y, Misra H, Liu D. Genistein induces pancreatic beta-cell proliferation through activation of multiple signaling pathways and prevents insulin-deficient diabetes in mice. Endocrinology. 151: 3026-37. PMID 20484465 DOI: 10.1210/En.2009-1294 |
0.377 |
|
| 2010 |
Zhang J, O'Donnell JJ, Holian O, Vincent PA, Kim KS, Lum H. P120 catenin represses transcriptional activity through Kaiso in endothelial cells. Microvascular Research. 80: 233-9. PMID 20382170 DOI: 10.1016/J.Mvr.2010.04.001 |
0.654 |
|
| 2008 |
Qiao J, Holian O, Lee BS, Huang F, Zhang J, Lum H. Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA. American Journal of Physiology. Cell Physiology. 295: C1161-8. PMID 18768928 DOI: 10.1152/Ajpcell.00139.2008 |
0.626 |
|
| 2007 |
Ke Y, Lum H, Solaro RJ. Inhibition of endothelial barrier dysfunction by P21-activated kinase-1. Canadian Journal of Physiology and Pharmacology. 85: 281-8. PMID 17612635 DOI: 10.1139/y06-100 |
0.444 |
|
| 2007 |
Huang F, Mehta D, Predescu S, Kim KS, Lum H. A novel lysophospholipid- and pH-sensitive receptor, GPR4, in brain endothelial cells regulates monocyte transmigration. Endothelium : Journal of Endothelial Cell Research. 14: 25-34. PMID 17364894 DOI: 10.1080/10623320601177288 |
0.519 |
|
| 2006 |
Qiao J, Huang F, Naikawadi RP, Kim KS, Said T, Lum H. Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L91-101. PMID 16461426 DOI: 10.1152/Ajplung.00508.2005 |
0.511 |
|
| 2005 |
Carvey PM, Zhao CH, Hendey B, Lum H, Trachtenberg J, Desai BS, Snyder J, Zhu YG, Ling ZD. 6-Hydroxydopamine-induced alterations in blood-brain barrier permeability. The European Journal of Neuroscience. 22: 1158-68. PMID 16176358 DOI: 10.1111/J.1460-9568.2005.04281.X |
0.302 |
|
| 2005 |
Kim KS, Ren J, Jiang Y, Ebrahem Q, Tipps R, Cristina K, Xiao YJ, Qiao J, Taylor KL, Lum H, Anand-Apte B, Xu Y. GPR4 plays a critical role in endothelial cell function and mediates the effects of sphingosylphosphorylcholine. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 819-21. PMID 15857892 DOI: 10.1096/Fj.04-2988Fje |
0.523 |
|
| 2005 |
Huang F, Subbaiah PV, Holian O, Zhang J, Johnson A, Gertzberg N, Lum H. Lysophosphatidylcholine increases endothelial permeability: role of PKCalpha and RhoA cross talk. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L176-85. PMID 15764646 DOI: 10.1152/Ajplung.00003.2005 |
0.672 |
|
| 2005 |
Patterson CE, Lum H, Johan Groeneveld AB. Chapter 15 Advances in protection of endothelial barrier function Advances in Molecular and Cell Biology. 35: 423-470. DOI: 10.1016/S1569-2558(05)35015-6 |
0.394 |
|
| 2005 |
Lum H. Chapter 3 The activated endothelial cell phenotype Advances in Molecular and Cell Biology. 35: 65-104. DOI: 10.1016/S1569-2558(05)35003-X |
0.444 |
|
| 2004 |
Rochais F, Vandecasteele G, Lefebvre F, Lugnier C, Lum H, Mazet JL, Cooper DM, Fischmeister R. Negative feedback exerted by cAMP-dependent protein kinase and cAMP phosphodiesterase on subsarcolemmal cAMP signals in intact cardiac myocytes: an in vivo study using adenovirus-mediated expression of CNG channels. The Journal of Biological Chemistry. 279: 52095-105. PMID 15466415 DOI: 10.1074/Jbc.M405697200 |
0.367 |
|
| 2004 |
Meja KK, Catley MC, Cambridge LM, Barnes PJ, Lum H, Newton R, Giembycz MA. Adenovirus-mediated delivery and expression of a cAMP-dependent protein kinase inhibitor gene to BEAS-2B epithelial cells abolishes the anti-inflammatory effects of rolipram, salbutamol, and prostaglandin E2: a comparison with H-89. The Journal of Pharmacology and Experimental Therapeutics. 309: 833-44. PMID 14747610 DOI: 10.1124/Jpet.103.060020 |
0.417 |
|
| 2003 |
Lum H, Qiao J, Walter RJ, Huang F, Subbaiah PV, Kim KS, Holian O. Inflammatory stress increases receptor for lysophosphatidylcholine in human microvascular endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology. 285: H1786-9. PMID 12805023 DOI: 10.1152/Ajpheart.00359.2003 |
0.454 |
|
| 2003 |
Qiao J, Huang F, Lum H. PKA inhibits RhoA activation: a protection mechanism against endothelial barrier dysfunction. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L972-80. PMID 12588708 DOI: 10.1152/Ajplung.00429.2002 |
0.562 |
|
| 2002 |
Boo YC, Hwang J, Sykes M, Michell BJ, Kemp BE, Lum H, Jo H. Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism. American Journal of Physiology. Heart and Circulatory Physiology. 283: H1819-28. PMID 12384459 DOI: 10.1152/Ajpheart.00214.2002 |
0.453 |
|
| 2002 |
Lum H, Hao Z, Gayle D, Kumar P, Patterson CE, Uhler MD. Vascular endothelial cells express isoforms of protein kinase A inhibitor. American Journal of Physiology. Cell Physiology. 282: C59-66. PMID 11742798 DOI: 10.1152/Ajpcell.00256.2001 |
0.487 |
|
| 2001 |
Lum H. Lysophospholipids in the regulation of endothelial barrier function. American Journal of Physiology-Lung Cellular and Molecular Physiology. 281. PMID 11704527 DOI: 10.1152/Ajplung.2001.281.6.L1335 |
0.342 |
|
| 2001 |
Patterson CE, Lum H. Update on pulmonary edema: The role and regulation of endothelial barrier function Endothelium: Journal of Endothelial Cell Research. 8: 75-105. PMID 11572478 DOI: 10.3109/10623320109165319 |
0.394 |
|
| 2001 |
Lum H, Podolski JL, Gurnack ME, Schulz IT, Huang F, Holian O. Protein phosphatase 2B inhibitor potentiates endothelial PKC activity and barrier dysfunction. American Journal of Physiology-Lung Cellular and Molecular Physiology. 281. PMID 11504680 DOI: 10.1152/Ajplung.2001.281.3.L546 |
0.52 |
|
| 2001 |
Lum H, Roebuck KA. Oxidant stress and endothelial cell dysfunction American Journal of Physiology - Cell Physiology. 280. PMID 11245588 DOI: 10.1152/Ajpcell.2001.280.4.C719 |
0.497 |
|
| 2000 |
Patterson CE, Lum H, Schaphorst KL, Verin AD, Garcia JGN. Regulation of endothelial barrier function by the cAMP-dependent protein kinase Endothelium: Journal of Endothelial Cell Research. 7: 287-308+III. PMID 11201526 DOI: 10.3109/10623320009072215 |
0.518 |
|
| 1999 |
Lum H, Jaffe HA, Schulz IT, Masood A, RayChaudhury A, Green RD. Expression of PKA inhibitor (PKI) gene abolishes cAMP-mediated protection to endothelial barrier dysfunction American Journal of Physiology - Cell Physiology. 277. PMID 10484345 DOI: 10.1152/Ajpcell.1999.277.3.C580 |
0.493 |
|
| 1998 |
Yan W, Tiruppathi C, Lum H, Qiao R, Malik AB. Protein kinase Cβ regulates heterologous desensitization of thrombin receptor (PAR-1) in endothelial cells. American Journal of Physiology. Cell Physiology. 274: C387-C395. PMID 29590937 DOI: 10.1152/Ajpcell.1998.274.2.C387 |
0.495 |
|
| 1998 |
Vuong PT, Malik AB, Nagpala PG, Lum H. Protein kinase C beta modulates thrombin-induced Ca2+ signaling and endothelial permeability increase. Journal of Cellular Physiology. 175: 379-87. PMID 9572483 DOI: 10.1002/(Sici)1097-4652(199806)175:3<379::Aid-Jcp16>3.0.Co;2-0 |
0.448 |
|
| 1997 |
Aschner JL, Lum H, Fletcher PW, Malik AB. Bradykinin- and thrombin-induced increases in endothelial permeability occur independently of phospholipase C but require protein kinase C activation. Journal of Cellular Physiology. 173: 387-96. PMID 9369952 DOI: 10.1002/(Sici)1097-4652(199712)173:3<387::Aid-Jcp11>3.0.Co;2-9 |
0.473 |
|
| 1997 |
Lum H, Malik AB. Mechanisms of increased endothelial permeability. Canadian Journal of Physiology and Pharmacology. 74: 787-800. PMID 8946065 DOI: 10.1139/Y96-081 |
0.509 |
|
| 1996 |
Yan W, Tiruppathi C, Qiao R, Lum H, Malik AB. Tumor necrosis factor decreases thrombin receptor expression in endothelial cells. Journal of Cellular Physiology. 166: 561-7. PMID 8600159 DOI: 10.1002/(Sici)1097-4652(199603)166:3<561::Aid-Jcp10>3.0.Co;2-A |
0.362 |
|
| 1996 |
Nagpala PG, Malik AB, Vuong PT, Lum H. Protein kinase C beta 1 overexpression augments phorbol ester-induced increase in endothelial permeability. Journal of Cellular Physiology. 166: 249-55. PMID 8591984 DOI: 10.1002/(Sici)1097-4652(199602)166:2<249::Aid-Jcp2>3.0.Co;2-P |
0.386 |
|
| 1995 |
Qiao RL, Yan W, Lum H, Malik AB. Arg-Gly-Asp peptide increases endothelial hydraulic conductivity: comparison with thrombin response. The American Journal of Physiology. 269: C110-7. PMID 7631737 DOI: 10.1152/Ajpcell.1995.269.1.C110 |
0.449 |
|
| 1994 |
Lum H, Andersen TT, Fenton JW, Malik AB. Thrombin receptor activation peptide induces pulmonary vasoconstriction American Journal of Physiology - Cell Physiology. 266. PMID 8141259 DOI: 10.1152/Ajpcell.1994.266.2.C448 |
0.316 |
|
| 1994 |
Lum H, Malik AB. Regulation of vascular endothelial barrier function. The American Journal of Physiology. 267: L223-41. PMID 7943249 DOI: 10.1152/Ajplung.1994.267.3.L223 |
0.503 |
|
| 1994 |
Lum H, Gibbs L, Lai L, Malik AB. CD18 integrin-dependent endothelial injury: effects of opsonized zymosan and phorbol ester activation. Journal of Leukocyte Biology. 55: 58-63. PMID 7904295 DOI: 10.1002/Jlb.55.1.58 |
0.432 |
|
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