Diane Mathis - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Immunology, Cell Biology

354 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Li C, Wang G, Sivasami P, Ramirez RN, Zhang Y, Benoist C, Mathis D. Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metabolism. PMID 34256015 DOI: 10.1016/j.cmet.2021.06.007  1
2021 Zemmour D, Charbonnier LM, Leon J, Six E, Keles S, Delville M, Benamar M, Baris S, Zuber J, Chen K, Neven B, Garcia-Lloret MI, Ruemmele FM, Brugnara C, Cerf-Bensussan N, ... ... Mathis D, et al. Single-cell analysis of FOXP3 deficiencies in humans and mice unmasks intrinsic and extrinsic CD4 T cell perturbations. Nature Immunology. 22: 607-619. PMID 33833438 DOI: 10.1038/s41590-021-00910-8  1
2021 Muñoz-Rojas AR, Mathis D. Tissue regulatory T cells: regulatory chameleons. Nature Reviews. Immunology. PMID 33772242 DOI: 10.1038/s41577-021-00519-w  0.44
2021 Kiner E, Willie E, Vijaykumar B, Chowdhary K, Schmutz H, Chandler J, Schnell A, Thakore PI, LeGros G, Mostafavi S, Mathis D, Benoist C. Publisher Correction: Gut CD4 T cell phenotypes are a continuum molded by microbes, not by T archetypes. Nature Immunology. PMID 33772225 DOI: 10.1038/s41590-021-00916-2  1
2021 Li C, Muñoz-Rojas AR, Wang G, Mann AO, Benoist C, Mathis D. PPARγ marks splenic precursors of multiple nonlymphoid-tissue Treg compartments. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33753509 DOI: 10.1073/pnas.2025197118  1
2021 Yan Y, Ramanan D, Rozenberg M, McGovern K, Rastelli D, Vijaykumar B, Yaghi O, Voisin T, Mosaheb M, Chiu I, Itzkovitz S, Rao M, Mathis D, Benoist C. Interleukin-6 produced by enteric neurons regulates the number and phenotype of microbe-responsive regulatory T cells in the gut. Immunity. 54: 499-513.e5. PMID 33691135 DOI: 10.1016/j.immuni.2021.02.002  1
2021 Vasanthakumar A, Chisanga D, Blume J, Gloury R, Britt K, Henstridge DC, Zhan Y, Torres SV, Liene S, Collins N, Cao E, Sidwell T, Li C, Spallanzani RG, Liao Y, ... ... Mathis D, et al. Author Correction: Sex-specific adipose tissue imprinting of regulatory T cells. Nature. PMID 33674801 DOI: 10.1038/s41586-020-2251-7  0.56
2021 Kiner E, Willie E, Vijaykumar B, Chowdhary K, Schmutz H, Chandler J, Schnell A, Thakore PI, LeGros G, Mostafavi S, Mathis D, Benoist C. Gut CD4 T cell phenotypes are a continuum molded by microbes, not by T archetypes. Nature Immunology. PMID 33462454 DOI: 10.1038/s41590-020-00836-7  1
2020 Galván-Peña S, Leon J, Chowdhary K, Michelson DA, Vijaykumar B, Yang L, Magnuson A, Manickas-Hill Z, Piechocka-Trocha A, Worrall DP, Hall KE, Ghebremichael M, Walker BD, Li J, Yu XG, ... Mathis D, et al. Profound Treg perturbations correlate with COVID-19 severity. Biorxiv : the Preprint Server For Biology. PMID 33330871 DOI: 10.1101/2020.12.11.416180  1
2020 Ramanan D, Sefik E, Galván-Peña S, Wu M, Yang L, Yang Z, Kostic A, Golovkina TV, Kasper DL, Mathis D, Benoist C. An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint. Cell. PMID 32402238 DOI: 10.1016/J.Cell.2020.04.030  1
2020 Huoh YS, Wu B, Park S, Yang D, Bansal K, Greenwald E, Wong WP, Mathis D, Hur S. Dual functions of Aire CARD multimerization in the transcriptional regulation of T cell tolerance. Nature Communications. 11: 1625. PMID 32242017 DOI: 10.1038/S41467-020-15448-W  0.32
2020 Li C, Spallanzani RG, Mathis D. Visceral adipose tissue Tregs and the cells that nurture them. Immunological Reviews. PMID 32162339 DOI: 10.1111/Imr.12850  0.56
2020 Vasanthakumar A, Chisanga D, Blume J, Gloury R, Britt K, Henstridge DC, Zhan Y, Torres SV, Liene S, Collins N, Cao E, Sidwell T, Li C, Spallanzani RG, Liao Y, ... ... Mathis D, et al. Sex-specific adipose tissue imprinting of regulatory T cells. Nature. PMID 32103173 DOI: 10.1038/S41586-020-2040-3  0.56
2020 Wang K, Yaghi OK, Spallanzani RG, Chen X, Zemmour D, Lai N, Chiu IM, Benoist C, Mathis D. Neuronal, stromal, and T-regulatory cell crosstalk in murine skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. PMID 32102913 DOI: 10.1073/Pnas.1922559117  1
2020 Hu B, Jin C, Zeng X, Resch JM, Jedrychowski MP, Yang Z, Desai BN, Banks AS, Lowell BB, Mathis D, Spiegelman BM. γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis. Nature. PMID 32076265 DOI: 10.1038/S41586-020-2028-Z  0.36
2020 Fernandes RA, Li C, Wang G, Yang X, Savvides CS, Glassman CR, Dong S, Luxenberg E, Sibener LV, Birnbaum ME, Benoist C, Mathis D, Garcia KC. Author response: Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo Elife. DOI: 10.7554/Elife.58463.Sa2  1
2019 Song X, Sun X, Oh SF, Wu M, Zhang Y, Zheng W, Geva-Zatorsky N, Jupp R, Mathis D, Benoist C, Kasper DL. Microbial bile acid metabolites modulate gut RORγ regulatory T cell homeostasis. Nature. PMID 31875848 DOI: 10.1038/S41586-019-1865-0  1
2019 Cho J, Kuswanto W, Benoist C, Mathis D. T cell receptor specificity drives accumulation of a reparative population of regulatory T cells within acutely injured skeletal muscle. Proceedings of the National Academy of Sciences of the United States of America. PMID 31822623 DOI: 10.1073/Pnas.1914848116  1
2019 Pratama A, Schnell A, Mathis D, Benoist C. Developmental and cellular age direct conversion of CD4 T cells into RORγ or Helios colon Treg cells. The Journal of Experimental Medicine. PMID 31685531 DOI: 10.1084/Jem.20190428  1
2019 Syed I, Rubinde Celis MF, Mohan JF, Moraes-Vieira PM, Vijayakumar A, Nelson AT, Siegel D, Saghatelian A, Mathis D, Kahn BB. PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice. The Journal of Clinical Investigation. 129. PMID 31380811 DOI: 10.1172/Jci122445  0.36
2019 Spallanzani RG, Zemmour D, Xiao T, Jayewickreme T, Li C, Bryce PJ, Benoist C, Mathis D. Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors. Science Immunology. 4. PMID 31053654 DOI: 10.1126/Sciimmunol.Aaw3658  1
2019 Tuncel J, Benoist C, Mathis D. T cell anergy in perinatal mice is promoted by T reg cells and prevented by IL-33. The Journal of Experimental Medicine. PMID 30988052 DOI: 10.1084/Jem.20182002  1
2019 Burzyn D, Wagers A, Mathis D, Cerletti M. Methods of Isolation and Analysis of TREG Immune Infiltrates from Injured and Dystrophic Skeletal Muscle. Methods in Molecular Biology (Clifton, N.J.). 1899: 229-237. PMID 30649776 DOI: 10.1007/978-1-4939-8938-6_16  0.8
2019 Li C, DiSpirito JR, Zemmour D, Spallanzani RG, Kuswanto W, Benoist C, Mathis D. Abstract B065: Tracking adipose-tissue Treg provenance, dependencies, and activities via T-cell receptor transgenic mice Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-B065  1
2018 Magnuson AM, Kiner E, Ergun A, Park JS, Asinovski N, Ortiz-Lopez A, Kilcoyne A, Paoluzzi-Tomada E, Weissleder R, Mathis D, Benoist C. Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348759 DOI: 10.1073/Pnas.1810580115  1
2018 DiSpirito JR, Zemmour D, Ramanan D, Cho J, Zilionis R, Klein AM, Benoist C, Mathis D. Molecular diversification of regulatory T cells in nonlymphoid tissues. Science Immunology. 3. PMID 30217811 DOI: 10.1126/Sciimmunol.Aat5861  1
2018 Li C, DiSpirito JR, Zemmour D, Spallanzani RG, Kuswanto W, Benoist C, Mathis D. TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Cell. PMID 29887374 DOI: 10.1016/J.Cell.2018.05.004  1
2018 Zemmour D, Zilionis R, Kiner E, Klein AM, Mathis D, Benoist C. Publisher Correction: Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR. Nature Immunology. PMID 29725080 DOI: 10.1038/S41590-018-0104-4  1
2018 Panduro M, Benoist C, Mathis D. Tcells limit IFN-γ production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 29476012 DOI: 10.1073/Pnas.1800618115  1
2018 Zemmour D, Zilionis R, Kiner E, Klein AM, Mathis D, Benoist C. Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR. Nature Immunology. PMID 29434354 DOI: 10.1038/S41590-018-0051-0  1
2017 Kwon HK, Chen HM, Mathis D, Benoist C. FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29269391 DOI: 10.1073/Pnas.1718599115  1
2017 Kwon HK, Chen HM, Mathis D, Benoist C. Different molecular complexes that mediate transcriptional induction and repression by FoxP3. Nature Immunology. PMID 28892470 DOI: 10.1038/Ni.3835  1
2017 Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C. Imaging the emergence and natural progression of spontaneous autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28839093 DOI: 10.1073/Pnas.1707381114  1
2017 Silverman M, Kua L, Tanca A, Pala M, Palomba A, Tanes C, Bittinger K, Uzzau S, Benoist C, Mathis D. Protective major histocompatibility complex allele prevents type 1 diabetes by shaping the intestinal microbiota early in ontogeny. Proceedings of the National Academy of Sciences of the United States of America. PMID 28831005 DOI: 10.1073/Pnas.1712280114  1
2017 Zemmour D, Pratama A, Loughhead SM, Mathis D, Benoist C. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396406 DOI: 10.1073/Pnas.1700946114  1
2017 Yissachar N, Zhou Y, Ung L, Lai NY, Mohan JF, Ehrlicher A, Weitz DA, Kasper DL, Chiu IM, Mathis D, Benoist C. An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk. Cell. PMID 28262351 DOI: 10.1016/J.Cell.2017.02.009  1
2017 Geva-Zatorsky N, Sefik E, Kua L, Pasman L, Tan TG, Ortiz-Lopez A, Yanortsang TB, Yang L, Jupp R, Mathis D, Benoist C, Kasper DL. Mining the Human Gut Microbiota for Immunomodulatory Organisms. Cell. PMID 28215708 DOI: 10.1016/J.Cell.2017.01.022  1
2017 Bansal K, Yoshida H, Benoist C, Mathis D. The transcriptional regulator Aire binds to and activates super-enhancers. Nature Immunology. PMID 28135252 DOI: 10.1038/Ni.3675  1
2016 Tan TG, Sefik E, Geva-Zatorsky N, Kua L, Naskar D, Teng F, Pasman L, Ortiz-Lopez A, Jupp R, Wu HJ, Kasper DL, Benoist C, Mathis D. Identifying species of symbiont bacteria from the human gut that, alone, can induce intestinal Th17 cells in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911839 DOI: 10.1073/Pnas.1617460113  1
2016 Tan TG, Mathis D, Benoist C. Singular role for T-BET+CXCR3+ regulatory T cells in protection from autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27872297 DOI: 10.1073/Pnas.1616710113  1
2016 Fujikado N, Mann AO, Bansal K, Romito KR, Ferre EM, Rosenzweig SD, Lionakis MS, Benoist C, Mathis D. Aire Inhibits the Generation of a Perinatal Population of Interleukin-17A-Producing γδ T Cells to Promote Immunologic Tolerance. Immunity. 45: 999-1012. PMID 27851927 DOI: 10.1016/J.Immuni.2016.10.023  1
2016 Moodley D, Yoshida H, Mostafavi S, Asinovski N, Ortiz-Lopez A, Symanowicz P, Telliez JB, Hegen M, Clark JD, Mathis D, Benoist C. Network pharmacology of JAK inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 27516546 DOI: 10.1073/Pnas.1610253113  1
2016 Panduro M, Benoist C, Mathis D. Tissue Tregs. Annual Review of Immunology. 34: 609-33. PMID 27168246 DOI: 10.1146/annurev-immunol-032712-095948  1
2016 Mathis D, Benoist C. Promiscuity Promotes Tolerance. Journal of Immunology (Baltimore, Md. : 1950). 196: 2913-4. PMID 26994302 DOI: 10.4049/Jimmunol.1600225  1
2016 Kuswanto W, Burzyn D, Panduro M, Wang KK, Jang YC, Wagers AJ, Benoist C, Mathis D. Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells. Immunity. 44: 355-67. PMID 26872699 DOI: 10.1016/J.Immuni.2016.01.009  1
2016 Mostafavi S, Yoshida H, Moodley D, LeBoité H, Rothamel K, Raj T, Ye CJ, Chevrier N, Zhang SY, Feng T, Lee M, Casanova JL, Clark JD, Hegen M, Telliez JB, ... ... Mathis D, et al. Parsing the Interferon Transcriptional Network and Its Disease Associations. Cell. 164: 564-578. PMID 26824662 DOI: 10.1016/J.Cell.2015.12.032  1
2016 Dépis F, Kwon HK, Mathis D, Benoist C. Unstable FoxP3+ T regulatory cells in NZW mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 26768846 DOI: 10.1073/Pnas.1524660113  0.64
2016 Mathis D, Benoist C. Promiscuity promotes tolerance Journal of Immunology. 196: 2913-2914. DOI: 10.4049/jimmunol.1600225  1
2016 Li C, Benoist C, Mathis D. Abstract A063: Dissecting adipose tissue Treg differentiation and function in metabolism and obesity-associated cancer using TCR transgenic mice Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A063  1
2015 Yan D, Farache J, Mathis D, Benoist C. Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3. Proceedings of the National Academy of Sciences of the United States of America. 112: 14942-7. PMID 26627244 DOI: 10.1073/Pnas.1520393112  1
2015 DiSpirito JR, Mathis D. Immunological contributions to adipose tissue homeostasis. Seminars in Immunology. PMID 26616665 DOI: 10.1016/J.Smim.2015.10.005  1
2015 Clardy SM, Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R. Rapid, high efficiency isolation of pancreatic ß-cells. Scientific Reports. 5: 13681. PMID 26330153 DOI: 10.1038/Srep13681  1
2015 Sefik E, Geva-Zatorsky N, Oh S, Konnikova L, Zemmour D, McGuire AM, Burzyn D, Ortiz-Lopez A, Lobera M, Yang J, Ghosh S, Earl A, Snapper SB, Jupp R, Kasper D, ... Mathis D, et al. Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells. Science (New York, N.Y.). PMID 26272906 DOI: 10.1126/Science.Aaa9420  0.64
2015 Meredith M, Zemmour D, Mathis D, Benoist C. Aire controls gene expression in the thymic epithelium with ordered stochasticity. Nature Immunology. 16: 942-9. PMID 26237550 DOI: 10.1038/Ni.3247  0.64
2015 Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, Anderson MS, Prinjha RK, Tarakhovsky A, Benoist C, Mathis D. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 112: E4448-57. PMID 26216992 DOI: 10.1073/Pnas.1512081112  1
2015 Kolodin D, van Panhuys N, Li C, Magnuson AM, Cipolletta D, Miller CM, Wagers A, Germain RN, Benoist C, Mathis D. Antigen- and cytokine-driven accumulation of regulatory T cells in visceral adipose tissue of lean mice. Cell Metabolism. 21: 543-57. PMID 25863247 DOI: 10.1016/J.Cmet.2015.03.005  1
2015 Goettel JA, Biswas S, Lexmond WS, Yeste A, Passerini L, Patel B, Yang S, Sun J, Ouahed J, Shouval DS, McCann KJ, Horwitz BH, Mathis D, Milford EL, Notarangelo LD, et al. Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3. Blood. 125: 3886-95. PMID 25833964 DOI: 10.1182/Blood-2014-12-618363  1
2015 De Jager PL, Hacohen N, Mathis D, Regev A, Stranger BE, Benoist C. ImmVar project: Insights and design considerations for future studies of "healthy" immune variation. Seminars in Immunology. 27: 51-7. PMID 25819567 DOI: 10.1016/J.Smim.2015.03.003  1
2015 Yang S, Fujikado N, Kolodin D, Benoist C, Mathis D. Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance. Science (New York, N.Y.). 348: 589-94. PMID 25791085 DOI: 10.1126/Science.Aaa7017  1
2015 Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C, Mathis D, Weissleder R. Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients. Proceedings of the National Academy of Sciences of the United States of America. 112: 2139-44. PMID 25650428 DOI: 10.1073/Pnas.1424993112  1
2015 Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C. Population dynamics of islet-infiltrating cells in autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 112: 1511-6. PMID 25605891 DOI: 10.1073/Pnas.1423769112  1
2015 Cipolletta D, Cohen P, Spiegelman BM, Benoist C, Mathis D. Appearance and disappearance of the mRNA signature characteristic of Treg cells in visceral adipose tissue: age, diet, and PPARγ effects. Proceedings of the National Academy of Sciences of the United States of America. 112: 482-7. PMID 25550516 DOI: 10.1073/Pnas.1423486112  1
2015 Yoshida H, Bansal K, Schaefer U, Chapman T, Rioja I, Proekt I, Anderson MS, Prinjha RK, Tarakhovsky A, Benoist C, Mathis D. Brd4 bridges the transcriptional regulators, Aire and P-TEFb, to promote elongation of peripheral-tissue antigen transcripts in thymic stromal cells Proceedings of the National Academy of Sciences of the United States of America. 112: E4448-E4457. DOI: 10.1073/pnas.1512081112  1
2015 Clardy SM, Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R. Rapid, high efficiency isolation of pancreatic ß-cells Scientific Reports. 5. DOI: 10.1038/srep13681  0.64
2014 Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells. Elife. 3: e04631. PMID 25407682 DOI: 10.7554/Elife.04631  1
2014 Mingueneau M, Krishnaswamy S, Spitzer MH, Bendall SC, Stone EL, Hedrick SM, Pe'er D, Mathis D, Nolan GP, Benoist C. Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 16466-71. PMID 25362052 DOI: 10.1073/Pnas.1419337111  1
2014 Mostafavi S, Ortiz-Lopez A, Bogue MA, Hattori K, Pop C, Koller D, Mathis D, Benoist C. Variation and genetic control of gene expression in primary immunocytes across inbred mouse strains. Journal of Immunology (Baltimore, Md. : 1950). 193: 4485-96. PMID 25267973 DOI: 10.4049/Jimmunol.1401280  1
2014 Ye CJ, Feng T, Kwon HK, Raj T, Wilson MT, Asinovski N, McCabe C, Lee MH, Frohlich I, Paik HI, Zaitlen N, Hacohen N, Stranger B, De Jager P, Mathis D, et al. Intersection of population variation and autoimmunity genetics in human T cell activation. Science (New York, N.Y.). 345: 1254665. PMID 25214635 DOI: 10.1126/Science.1254665  1
2014 Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D. Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proceedings of the National Academy of Sciences of the United States of America. 111: 11419-24. PMID 25049388 DOI: 10.1073/Pnas.1410854111  1
2014 Gutierrez DA, Fu W, Schonefeldt S, Feyerabend TB, Ortiz-Lopez A, Lampi Y, Liston A, Mathis D, Rodewald HR. Type 1 diabetes in NOD mice unaffected by mast cell deficiency. Diabetes. 63: 3827-34. PMID 24917576 DOI: 10.2337/Db14-0372  1
2014 Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, Feng T, Lee M, Asinovski N, Frohlich I, Imboywa S, Von Korff A, Okada Y, Patsopoulos NA, Davis S, ... ... Mathis D, et al. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science (New York, N.Y.). 344: 519-23. PMID 24786080 DOI: 10.1126/Science.1249547  1
2014 Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D. Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proceedings of the National Academy of Sciences of the United States of America. 111: 6696-701. PMID 24753589 DOI: 10.1073/Pnas.1405634111  1
2014 Joller N, Lozano E, Burkett PR, Patel B, Xiao S, Zhu C, Xia J, Tan TG, Sefik E, Yajnik V, Sharpe AH, Quintana FJ, Mathis D, Benoist C, Hafler DA, et al. Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses. Immunity. 40: 569-81. PMID 24745333 DOI: 10.1016/J.Immuni.2014.02.012  1
2014 Ferraro A, D'Alise AM, Raj T, Asinovski N, Phillips R, Ergun A, Replogle JM, Bernier A, Laffel L, Stranger BE, De Jager PL, Mathis D, Benoist C. Interindividual variation in human T regulatory cells. Proceedings of the National Academy of Sciences of the United States of America. 111: E1111-20. PMID 24610777 DOI: 10.1073/Pnas.1401343111  1
2014 Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, ... ... Mathis D, et al. Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch. Cell. 156: 304-16. PMID 24439384 DOI: 10.1016/J.Cell.2013.12.021  1
2014 Giraud M, Jmari N, Du L, Carallis F, Nieland TJ, Perez-Campo FM, Bensaude O, Root DE, Hacohen N, Mathis D, Benoist C. An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription. Proceedings of the National Academy of Sciences of the United States of America. 111: 1491-6. PMID 24434558 DOI: 10.1073/Pnas.1323535111  1
2014 Clardy SM, Keliher EJ, Mohan JF, Sebas M, Benoist C, Mathis D, Weissleder R. Fluorescent exendin-4 derivatives for pancreatic β-cell analysis. Bioconjugate Chemistry. 25: 171-7. PMID 24328216 DOI: 10.1021/Bc4005014  1
2014 Dirice E, Kahraman S, Jiang W, El Ouaamari A, De Jesus DF, Teo AK, Hu J, Kawamori D, Gaglia JL, Mathis D, Kulkarni RN. Soluble factors secreted by T cells promote β-cell proliferation. Diabetes. 63: 188-202. PMID 24089508 DOI: 10.2337/Db13-0204  1
2013 Burzyn D, Kuswanto W, Kolodin D, Shadrach JL, Cerletti M, Jang Y, Sefik E, Tan TG, Wagers AJ, Benoist C, Mathis D. A special population of regulatory T cells potentiates muscle repair. Cell. 155: 1282-95. PMID 24315098 DOI: 10.1016/J.Cell.2013.10.054  1
2013 Engin F, Yermalovich A, Nguyen T, Ngyuen T, Hummasti S, Fu W, Eizirik DL, Mathis D, Hotamisligil GS. Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes. Science Translational Medicine. 5: 211ra156. PMID 24225943 DOI: 10.1126/Scitranslmed.3006534  1
2013 Mathis D. A gut feeling about arthritis. Elife. 2: e01608. PMID 24192040 DOI: 10.7554/Elife.01608  1
2013 Burzyn D, Benoist C, Mathis D. Regulatory T cells in nonlymphoid tissues. Nature Immunology. 14: 1007-13. PMID 24048122 DOI: 10.1038/Ni.2683  1
2013 Li L, Nishio J, van Maurik A, Mathis D, Benoist C. Differential response of regulatory and conventional CD4⁺ lymphocytes to CD3 engagement: clues to a possible mechanism of anti-CD3 action? Journal of Immunology (Baltimore, Md. : 1950). 191: 3694-704. PMID 23986534 DOI: 10.4049/Jimmunol.1300408  1
2013 Ergun A, Doran G, Costello JC, Paik HH, Collins JJ, Mathis D, Benoist C. Differential splicing across immune system lineages. Proceedings of the National Academy of Sciences of the United States of America. 110: 14324-9. PMID 23934048 DOI: 10.1073/Pnas.1311839110  1
2013 Mathis D. Immunological goings-on in visceral adipose tissue. Cell Metabolism. 17: 851-9. PMID 23747244 DOI: 10.1016/J.Cmet.2013.05.008  1
2013 Sitrin J, Ring A, Garcia KC, Benoist C, Mathis D. Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2. The Journal of Experimental Medicine. 210: 1153-65. PMID 23650440 DOI: 10.1084/Jem.20122248  1
2013 Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, ... ... Mathis D, et al. The transcriptional landscape of αβ T cell differentiation. Nature Immunology. 14: 619-32. PMID 23644507 DOI: 10.1038/Ni.2590  1
2013 Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, ... ... Mathis D, et al. Identification of transcriptional regulators in the mouse immune system. Nature Immunology. 14: 633-43. PMID 23624555 DOI: 10.1038/Ni.2587  1
2013 Abbas AK, Benoist C, Bluestone JA, Campbell DJ, Ghosh S, Hori S, Jiang S, Kuchroo VK, Mathis D, Roncarolo MG, Rudensky A, Sakaguchi S, Shevach EM, Vignali DA, Ziegler SF. Regulatory T cells: recommendations to simplify the nomenclature. Nature Immunology. 14: 307-8. PMID 23507634 DOI: 10.1038/Ni.2554  1
2013 Yang S, Bansal K, Lopes J, Benoist C, Mathis D. Aire's plant homeodomain(PHD)-2 is critical for induction of immunological tolerance. Proceedings of the National Academy of Sciences of the United States of America. 110: 1833-8. PMID 23319629 DOI: 10.1073/Pnas.1222023110  1
2013 Wakamatsu E, Mathis D, Benoist C. Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 1023-8. PMID 23277554 DOI: 10.1073/Pnas.1220688110  1
2012 Shu CJ, Benoist C, Mathis D. The immune system's involvement in obesity-driven type 2 diabetes. Seminars in Immunology. 24: 436-42. PMID 23333525 DOI: 10.1016/J.Smim.2012.12.001  1
2012 Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C. A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells. Nature Immunology. 13: 972-80. PMID 22961053 DOI: 10.1038/Ni.2420  1
2012 Benoist C, Lanier L, Merad M, Mathis D. Consortium biology in immunology: the perspective from the Immunological Genome Project. Nature Reviews. Immunology. 12: 734-40. PMID 22955842 DOI: 10.1038/Nri3300  1
2012 Benoist C, Mathis D. Treg cells, life history, and diversity. Cold Spring Harbor Perspectives in Biology. 4: a007021. PMID 22952391 DOI: 10.1101/Cshperspect.A007021  1
2012 Chung H, Pamp SJ, Hill JA, Surana NK, Edelman SM, Troy EB, Reading NC, Villablanca EJ, Wang S, Mora JR, Umesaki Y, Mathis D, Benoist C, Relman DA, Kasper DL. Gut immune maturation depends on colonization with a host-specific microbiota. Cell. 149: 1578-93. PMID 22726443 DOI: 10.1016/J.Cell.2012.04.037  1
2012 Cipolletta D, Feuerer M, Li A, Kamei N, Lee J, Shoelson SE, Benoist C, Mathis D. PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells. Nature. 486: 549-53. PMID 22722857 DOI: 10.1038/Nature11132  1
2012 Darce J, Rudra D, Li L, Nishio J, Cipolletta D, Rudensky AY, Mathis D, Benoist C. An N-terminal mutation of the Foxp3 transcription factor alleviates arthritis but exacerbates diabetes. Immunity. 36: 731-41. PMID 22579475 DOI: 10.1016/J.Immuni.2012.04.007  1
2012 Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D. Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nature Immunology. 13: 361-8. PMID 22366893 DOI: 10.1038/Ni.2233  1
2012 Fassett MS, Jiang W, D'Alise AM, Mathis D, Benoist C. Nuclear receptor Nr4a1 modulates both regulatory T-cell (Treg) differentiation and clonal deletion. Proceedings of the National Academy of Sciences of the United States of America. 109: 3891-6. PMID 22345564 DOI: 10.1073/Pnas.1200090109  1
2012 Mingueneau M, Jiang W, Feuerer M, Mathis D, Benoist C. Thymic negative selection is functional in NOD mice. The Journal of Experimental Medicine. 209: 623-37. PMID 22329992 DOI: 10.1084/jem.20112593  1
2012 Rao SM, Auger JL, Gaillard P, Weissleder R, Wada E, Torres R, Kojima M, Benoist C, Mathis D, Binstadt BA. The neuropeptide neuromedin U promotes autoantibody-mediated arthritis. Arthritis Research & Therapy. 14: R29. PMID 22314006 DOI: 10.1186/Ar3732  1
2012 Giraud M, Yoshida H, Abramson J, Rahl PB, Young RA, Mathis D, Benoist C. Aire unleashes stalled RNA polymerase to induce ectopic gene expression in thymic epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 535-40. PMID 22203960 DOI: 10.1073/Pnas.1119351109  1
2012 Mathis D, Benoist C. The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding. Immunological Reviews. 245: 239-49. PMID 22168424 DOI: 10.1111/J.1600-065X.2011.01084.X  1
2011 Feyerabend TB, Weiser A, Tietz A, Stassen M, Harris N, Kopf M, Radermacher P, Möller P, Benoist C, Mathis D, Fehling HJ, Rodewald HR. Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity. Immunity. 35: 832-44. PMID 22101159 DOI: 10.1016/J.Immuni.2011.09.015  1
2011 Mathis D, Benoist C. Microbiota and autoimmune disease: the hosted self. Cell Host & Microbe. 10: 297-301. PMID 22018229 DOI: 10.1016/J.Chom.2011.09.007  1
2011 Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R. Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proceedings of the National Academy of Sciences of the United States of America. 108: 12815-20. PMID 21768367 DOI: 10.1073/Pnas.1109859108  1
2011 Cipolletta D, Kolodin D, Benoist C, Mathis D. Tissular T(regs): a unique population of adipose-tissue-resident Foxp3+CD4+ T cells that impacts organismal metabolism. Seminars in Immunology. 23: 431-7. PMID 21724410 DOI: 10.1016/J.Smim.2011.06.002  1
2011 Kriegel MA, Sefik E, Hill JA, Wu HJ, Benoist C, Mathis D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 11548-53. PMID 21709219 DOI: 10.1073/Pnas.1108924108  1
2011 Johnsen AK, Valdar W, Golden L, Ortiz-Lopez A, Hitzemann R, Flint J, Mathis D, Benoist C. Genome-wide and species-wide dissection of the genetics of arthritis severity in heterogeneous stock mice. Arthritis and Rheumatism. 63: 2630-40. PMID 21560115 DOI: 10.1002/Art.30425  1
2011 D'Alise AM, Ergun A, Hill JA, Mathis D, Benoist C. A cluster of coregulated genes determines TGF-beta-induced regulatory T-cell (Treg) dysfunction in NOD mice. Proceedings of the National Academy of Sciences of the United States of America. 108: 8737-42. PMID 21543717 DOI: 10.1073/Pnas.1105364108  1
2011 Mathis D, Shoelson SE. Immunometabolism: an emerging frontier. Nature Reviews. Immunology. 11: 81. PMID 21469396 DOI: 10.1038/Nri2922  1
2011 Bandukwala HS, Wu Y, Feuerer M, Chen Y, Barboza B, Ghosh S, Stroud JC, Benoist C, Mathis D, Rao A, Chen L. Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity. 34: 479-91. PMID 21458306 DOI: 10.1016/J.Immuni.2011.02.017  1
2011 Painter MW, Davis S, Hardy RR, Mathis D, Benoist C. Transcriptomes of the B and T lineages compared by multiplatform microarray profiling. Journal of Immunology (Baltimore, Md. : 1950). 186: 3047-57. PMID 21307297 DOI: 10.4049/Jimmunol.1002695  1
2011 Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R. Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. The Journal of Clinical Investigation. 121: 442-5. PMID 21123946 DOI: 10.1172/Jci44339  1
2010 Huang GJ, Smith AL, Gray DH, Cosgrove C, Singer BH, Edwards A, Sims S, Sim S, Parent JM, Johnsen A, Mott R, Mathis D, Klenerman P, Benoist C, Flint J. A genetic and functional relationship between T cells and cellular proliferation in the adult hippocampus. Plos Biology. 8: e1000561. PMID 21179499 DOI: 10.1371/Journal.Pbio.1000561  1
2010 Rubtsov YP, Niec RE, Josefowicz S, Li L, Darce J, Mathis D, Benoist C, Rudensky AY. Stability of the regulatory T cell lineage in vivo. Science (New York, N.Y.). 329: 1667-71. PMID 20929851 DOI: 10.1126/Science.1191996  1
2010 Yalcin B, Nicod J, Bhomra A, Davidson S, Cleak J, Farinelli L, ØsterÃ¥s M, Whitley A, Yuan W, Gan X, Goodson M, Klenerman P, Satpathy A, Mathis D, Benoist C, et al. Commercially available outbred mice for genome-wide association studies. Plos Genetics. 6: e1001085. PMID 20838427 DOI: 10.1371/Journal.Pgen.1001085  1
2010 Nishio J, Feuerer M, Wong J, Mathis D, Benoist C. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. The Journal of Experimental Medicine. 207: 1879-89. PMID 20679403 DOI: 10.1084/Jem.20100205  1
2010 Wu HJ, Ivanov II, Darce J, Hattori K, Shima T, Umesaki Y, Littman DR, Benoist C, Mathis D. Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. Immunity. 32: 815-27. PMID 20620945 DOI: 10.1016/J.Immuni.2010.06.001  1
2010 Koh AS, Kingston RE, Benoist C, Mathis D. Global relevance of Aire binding to hypomethylated lysine-4 of histone-3. Proceedings of the National Academy of Sciences of the United States of America. 107: 13016-21. PMID 20615959 DOI: 10.1073/Pnas.1004436107  1
2010 Jacobs JP, Ortiz-Lopez A, Campbell JJ, Gerard CJ, Mathis D, Benoist C. Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model. Arthritis and Rheumatism. 62: 1921-32. PMID 20506316 DOI: 10.1002/Art.27470  1
2010 Shoda L, Kreuwel H, Gadkar K, Zheng Y, Whiting C, Atkinson M, Bluestone J, Mathis D, Young D, Ramanujan S. The Type 1 Diabetes PhysioLab Platform: a validated physiologically based mathematical model of pathogenesis in the non-obese diabetic mouse. Clinical and Experimental Immunology. 161: 250-67. PMID 20491795 DOI: 10.1111/J.1365-2249.2010.04166.X  1
2010 Suwanai H, Wilcox MA, Mathis D, Benoist C. A defective Il15 allele underlies the deficiency in natural killer cell activity in nonobese diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 9305-10. PMID 20439722 DOI: 10.1073/Pnas.1004492107  1
2010 Iwai LK, Benoist C, Mathis D, White FM. Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. Journal of Proteome Research. 9: 3135-45. PMID 20438120 DOI: 10.1021/Pr100035B  1
2010 Feuerer M, Hill JA, Kretschmer K, von Boehmer H, Mathis D, Benoist C. Genomic definition of multiple ex vivo regulatory T cell subphenotypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 5919-24. PMID 20231436 DOI: 10.1073/Pnas.1002006107  1
2010 Monach PA, Nigrovic PA, Chen M, Hock H, Lee DM, Benoist C, Mathis D. Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1. Arthritis and Rheumatism. 62: 753-64. PMID 20191628 DOI: 10.1002/Art.27238  1
2010 Huang H, Benoist C, Mathis D. Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis. Proceedings of the National Academy of Sciences of the United States of America. 107: 4658-63. PMID 20176942 DOI: 10.1073/Pnas.1001074107  1
2010 Abramson J, Giraud M, Benoist C, Mathis D. Aire's partners in the molecular control of immunological tolerance. Cell. 140: 123-35. PMID 20085707 DOI: 10.1016/J.Cell.2009.12.030  1
2010 Mathis D, Benoist C. Levees of immunological tolerance. Nature Immunology. 11: 3-6. PMID 20016503 DOI: 10.1038/Ni.1833  1
2010 Tachibana M, Hori S, Sekiya T, Yoshimura A, Cretney E, Xin A, Masson F, Belz G, Nutt SL, Kallies A, Yamaguchi T, Kishi A, Osaki M, Sakaguchi S, Loser K, ... ... Mathis D, et al. Regulatory T cells session 2 (WS-045b) Chairpersons: Naganari Ohkura, Takayuki Yoshimoto International Immunology. 22. DOI: 10.1093/Intimm/Dxq309  1
2010 Bandukwala H, Wu Y, Feurer M, Chen Y, Koh KP, Ghosh S, Sundrud MS, Stroud JC, Benoist C, Mathis D, Rao A, Chen L, Zorca CE, Spilianakis CG, Flavell R, et al. Transcriptional control (SY4-4) Chairpersons: Toshinori Nakayama, Ellen Rothenberg International Immunology. 22. DOI: 10.1093/Intimm/Dxq290  1
2010 Abramson J, Giraud M, Koh A, Benoist C, Mathis D, Abbas A, Adorini L, Nagata S, Schmidt RE, Diamond B. Autoimmune mechanisms (SY2-2) Chairpersons: Shigekazu Nagata, Betty Diamond International Immunology. 22. DOI: 10.1093/Intimm/Dxq146  1
2009 Jacobs JP, Wu HJ, Benoist C, Mathis D. IL-17-producing T cells can augment autoantibody-induced arthritis. Proceedings of the National Academy of Sciences of the United States of America. 106: 21789-94. PMID 19955422 DOI: 10.1073/Pnas.0912152106  1
2009 Feuerer M, Shen Y, Littman DR, Benoist C, Mathis D. How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic islets. Immunity. 31: 654-64. PMID 19818653 DOI: 10.1016/J.Immuni.2009.08.023  1
2009 Monach PA, Hueber W, Kessler B, Tomooka BH, BenBarak M, Simmons BP, Wright J, Thornhill TS, Monestier M, Ploegh H, Robinson WH, Mathis D, Benoist C. A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 106: 15867-72. PMID 19720992 DOI: 10.1073/Pnas.0908032106  1
2009 Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U. Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis and Rheumatism. 60: 2314-24. PMID 19644878 DOI: 10.1002/Art.24704  1
2009 Feuerer M, Herrero L, Cipolletta D, Naaz A, Wong J, Nayer A, Lee J, Goldfine AB, Benoist C, Shoelson S, Mathis D. Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nature Medicine. 15: 930-9. PMID 19633656 DOI: 10.1038/Nm.2002  1
2009 Feuerer M, Hill JA, Mathis D, Benoist C. Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nature Immunology. 10: 689-95. PMID 19536194 DOI: 10.1038/Ni.1760  1
2009 Guerau-de-Arellano M, Martinic M, Benoist C, Mathis D. Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity. The Journal of Experimental Medicine. 206: 1245-52. PMID 19487417 DOI: 10.1084/jem.20090300  1
2009 Mathis D, Benoist C. Aire. Annual Review of Immunology. 27: 287-312. PMID 19302042 DOI: 10.1146/annurev.immunol.25.022106.141532  1
2009 Hill JA, Hall JA, Sun CM, Cai Q, Ghyselinck N, Chambon P, Belkaid Y, Mathis D, Benoist C. Response to Letter from Mucida et al Immunity. 30: 472-473. DOI: 10.1016/J.Immuni.2009.03.012  1
2009 Hazen M, McArdel S, Ercan A, Ortiz-Lopez A, Benoist C, Mathis D, Lee D. F.93. Modulation of Autoantibody Glycosylation during Arthritis in the K/BxN Mouse Clinical Immunology. 131. DOI: 10.1016/J.Clim.2009.03.349  1
2008 D'Alise AM, Auyeung V, Feuerer M, Nishio J, Fontenot J, Benoist C, Mathis D. The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proceedings of the National Academy of Sciences of the United States of America. 105: 19857-62. PMID 19073938 DOI: 10.1073/Pnas.0810713105  1
2008 Hill JA, Hall JA, Sun CM, Cai Q, Ghyselinck N, Chambon P, Belkaid Y, Mathis D, Benoist C. Retinoic acid enhances Foxp3 induction indirectly by relieving inhibition from CD4+CD44hi Cells. Immunity. 29: 758-70. PMID 19006694 DOI: 10.1016/J.Immuni.2008.09.018  1
2008 Nigrovic PA, Gray DH, Jones T, Hallgren J, Kuo FC, Chaletzky B, Gurish M, Mathis D, Benoist C, Lee DM. Genetic inversion in mast cell-deficient (Wsh) mice interrupts corin and manifests as hematopoietic and cardiac aberrancy. The American Journal of Pathology. 173: 1693-701. PMID 18988802 DOI: 10.2353/Ajpath.2008.080407  1
2008 Koh AS, Kuo AJ, Park SY, Cheung P, Abramson J, Bua D, Carney D, Shoelson SE, Gozani O, Kingston RE, Benoist C, Mathis D. Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 105: 15878-83. PMID 18840680 DOI: 10.1073/Pnas.0808470105  1
2008 Venanzi ES, Melamed R, Mathis D, Benoist C. The variable immunological self: genetic variation and nongenetic noise in Aire-regulated transcription. Proceedings of the National Academy of Sciences of the United States of America. 105: 15860-5. PMID 18838677 DOI: 10.1073/Pnas.0808070105  1
2008 Villaseñor J, Besse W, Benoist C, Mathis D. Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated. Proceedings of the National Academy of Sciences of the United States of America. 105: 15854-9. PMID 18836079 DOI: 10.1073/Pnas.0808069105  1
2008 Heng TS, Painter MW. The Immunological Genome Project: networks of gene expression in immune cells. Nature Immunology. 9: 1091-4. PMID 18800157 DOI: 10.1038/Ni1008-1091  1
2008 Guerau-de-Arellano M, Mathis D, Benoist C. Transcriptional impact of Aire varies with cell type. Proceedings of the National Academy of Sciences of the United States of America. 105: 14011-6. PMID 18780794 DOI: 10.1073/Pnas.0806616105  1
2008 Gavanescu I, Benoist C, Mathis D. B cells are required for Aire-deficient mice to develop multi-organ autoinflammation: A therapeutic approach for APECED patients. Proceedings of the National Academy of Sciences of the United States of America. 105: 13009-14. PMID 18755889 DOI: 10.1073/Pnas.0806874105  1
2008 Johnsen AK, Plenge RM, Butty V, Campbell C, Dieguez-Gonzalez R, Gomez-Reino JJ, Shadick N, Weinblatt M, Gonzalez A, Gregersen PK, Benoist C, Mathis D. A broad analysis of IL1 polymorphism and rheumatoid arthritis. Arthritis and Rheumatism. 58: 1947-57. PMID 18576312 DOI: 10.1002/Art.23592  1
2008 Butty V, Campbell C, Mathis D, Benoist C. Impact of diabetes susceptibility loci on progression from pre-diabetes to diabetes in at-risk individuals of the diabetes prevention trial-type 1 (DPT-1). Diabetes. 57: 2348-59. PMID 18556337 DOI: 10.2337/Db07-1736  1
2008 Monach PA, Mathis D, Benoist C. The K/BxN arthritis model. Current Protocols in Immunology / Edited by John E. Coligan ... [Et Al.]. Unit 15.22. PMID 18491295 DOI: 10.1002/0471142735.Im1522S81  1
2008 Haxhinasto S, Mathis D, Benoist C. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. The Journal of Experimental Medicine. 205: 565-74. PMID 18283119 DOI: 10.1084/Jem.20071477  1
2007 Hill JA, Feuerer M, Tash K, Haxhinasto S, Perez J, Melamed R, Mathis D, Benoist C. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity. 27: 786-800. PMID 18024188 DOI: 10.1016/J.Immuni.2007.09.010  1
2007 Feuerer M, Jiang W, Holler PD, Satpathy A, Campbell C, Bogue M, Mathis D, Benoist C. Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 104: 18181-6. PMID 17991775 DOI: 10.1073/Pnas.0708899104  1
2007 Gray DH, Gavanescu I, Benoist C, Mathis D. Danger-free autoimmune disease in Aire-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 18193-8. PMID 17991771 DOI: 10.1073/Pnas.0709160104  1
2007 Monach P, Hattori K, Huang H, Hyatt E, Morse J, Nguyen L, Ortiz-Lopez A, Wu HJ, Mathis D, Benoist C. The K/BxN mouse model of inflammatory arthritis: theory and practice. Methods in Molecular Medicine. 136: 269-82. PMID 17983155 DOI: 10.1007/978-1-59745-402-5_20  1
2007 Venanzi ES, Gray DH, Benoist C, Mathis D. Lymphotoxin pathway and Aire influences on thymic medullary epithelial cells are unconnected. Journal of Immunology (Baltimore, Md. : 1950). 179: 5693-700. PMID 17947641 DOI: 10.4049/Jimmunol.179.9.5693  1
2007 Gray D, Abramson J, Benoist C, Mathis D. Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire. The Journal of Experimental Medicine. 204: 2521-8. PMID 17908938 DOI: 10.1084/Jem.20070795  1
2007 Obst R, van Santen HM, Melamed R, Kamphorst AO, Benoist C, Mathis D. Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation. Proceedings of the National Academy of Sciences of the United States of America. 104: 15460-5. PMID 17881563 DOI: 10.1073/Pnas.0707331104  1
2007 Monach PA, Verschoor A, Jacobs JP, Carroll MC, Wagers AJ, Benoist C, Mathis D. Circulating C3 is necessary and sufficient for induction of autoantibody-mediated arthritis in a mouse model. Arthritis and Rheumatism. 56: 2968-74. PMID 17763447 DOI: 10.1002/Art.22859  1
2007 Wong J, Mathis D, Benoist C. TCR-based lineage tracing: no evidence for conversion of conventional into regulatory T cells in response to a natural self-antigen in pancreatic islets. The Journal of Experimental Medicine. 204: 2039-45. PMID 17724131 DOI: 10.1084/Jem.20070822  1
2007 Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. The Journal of Experimental Medicine. 204: 1911-22. PMID 17646407 DOI: 10.1084/Jem.20070285  1
2007 Mathis D, Benoist C. A decade of AIRE. Nature Reviews. Immunology. 7: 645-50. PMID 17641664 DOI: 10.1038/Nri2136  1
2007 Wong J, Obst R, Correia-Neves M, Losyev G, Mathis D, Benoist C. Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 7032-41. PMID 17513752 DOI: 10.4049/Jimmunol.178.11.7032  1
2007 Holler PD, Yamagata T, Jiang W, Feuerer M, Benoist C, Mathis D. The same genomic region conditions clonal deletion and clonal deviation to the CD8alphaalpha and regulatory T cell lineages in NOD versus C57BL/6 mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 7187-92. PMID 17438291 DOI: 10.1073/Pnas.0701777104  1
2007 Gavanescu I, Kessler B, Ploegh H, Benoist C, Mathis D. Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 104: 4583-7. PMID 17360567 DOI: 10.1073/Pnas.0700259104  1
2007 Liston A, Farr AG, Chen Z, Benoist C, Mathis D, Manley NR, Rudensky AY. Lack of Foxp3 function and expression in the thymic epithelium. The Journal of Experimental Medicine. 204: 475-80. PMID 17353370 DOI: 10.1084/Jem.20062465  1
2007 Haxhinasto S, Benoist C, Mathis D. Regulatory T-cell differentiation: Committed to control: a precocious choice? Immunology and Cell Biology. 85: 175-6. PMID 17310224 DOI: 10.1038/Sj.Icb.7100041  1
2007 Nigrovic PA, Binstadt BA, Monach PA, Johnsen A, Gurish M, Iwakura Y, Benoist C, Mathis D, Lee DM. Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1. Proceedings of the National Academy of Sciences of the United States of America. 104: 2325-30. PMID 17277081 DOI: 10.1073/Pnas.0610852103  1
2007 Nguyen LT, Jacobs J, Mathis D, Benoist C. Where FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritis. Arthritis and Rheumatism. 56: 509-20. PMID 17265486 DOI: 10.1002/Art.22272  1
2007 Hill JA, Benoist C, Mathis D. Treg cells: guardians for life. Nature Immunology. 8: 124-5. PMID 17242683 DOI: 10.1038/Ni0207-124  1
2007 Butty V, Roy M, Sabeti P, Besse W, Benoist C, Mathis D. Signatures of strong population differentiation shape extended haplotypes across the human CD28, CTLA4, and ICOS costimulatory genes. Proceedings of the National Academy of Sciences of the United States of America. 104: 570-5. PMID 17197413 DOI: 10.1073/Pnas.0610124104  1
2007 Rodacki M, Svoren B, Butty V, Besse W, Laffel L, Benoist C, Mathis D. Altered natural killer cells in type 1 diabetic patients. Diabetes. 56: 177-85. PMID 17192480 DOI: 10.2337/Db06-0493  1
2007 Mathis D, Benoist C. Yes, it does [2] Nature Reviews Immunology. 7: 1P. DOI: 10.1038/Nri2136-C2  1
2006 Chen Z, Stockton J, Mathis D, Benoist C. Modeling CTLA4-linked autoimmunity with RNA interference in mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 16400-5. PMID 17060611 DOI: 10.1073/Pnas.0607854103  1
2006 Wu Y, Borde M, Heissmeyer V, Feuerer M, Lapan AD, Stroud JC, Bates DL, Guo L, Han A, Ziegler SF, Mathis D, Benoist C, Chen L, Rao A. FOXP3 controls regulatory T cell function through cooperation with NFAT. Cell. 126: 375-87. PMID 16873067 DOI: 10.1016/J.Cell.2006.05.042  1
2006 Hyatt G, Melamed R, Park R, Seguritan R, Laplace C, Poirot L, Zucchelli S, Obst R, Matos M, Venanzi E, Goldrath A, Nguyen L, Luckey J, Yamagata T, Herman A, ... ... Mathis D, et al. Gene expression microarrays: glimpses of the immunological genome. Nature Immunology. 7: 686-91. PMID 16785882 DOI: 10.1038/Ni0706-686  1
2006 Benoist C, Germain RN, Mathis D. A plaidoyer for 'systems immunology'. Immunological Reviews. 210: 229-34. PMID 16623774 DOI: 10.1111/J.0105-2896.2006.00374.X  1
2006 Yamagata T, Benoist C, Mathis D. A shared gene-expression signature in innate-like lymphocytes. Immunological Reviews. 210: 52-66. PMID 16623764 DOI: 10.1182/Blood.V106.11.3903.3903  1
2006 Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D. Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science (New York, N.Y.). 311: 1775-8. PMID 16556845 DOI: 10.1126/Science.1124004  1
2006 Huang H, Kearney JF, Grusby MJ, Benoist C, Mathis D. Induction of tolerance in arthritogenic B cells with receptors of differing affinity for self-antigen. Proceedings of the National Academy of Sciences of the United States of America. 103: 3734-9. PMID 16505356 DOI: 10.1073/Pnas.0600214103  1
2006 Luckey CJ, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, Mathis D. Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 3304-9. PMID 16492737 DOI: 10.1073/Pnas.0511137103  1
2006 Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nature Immunology. 7: 284-92. PMID 16444258 DOI: 10.1038/Ni1306  1
2006 Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D. Response to Comment on Nishio et al. on Diabetes Reversal in NOD Mice Science. 314: 1243c-1243c. DOI: 10.1126/Science.1129919  0.32
2005 Turley SJ, Lee JW, Dutton-Swain N, Mathis D, Benoist C. Endocrine self and gut non-self intersect in the pancreatic lymph nodes. Proceedings of the National Academy of Sciences of the United States of America. 102: 17729-33. PMID 16317068 DOI: 10.1073/Pnas.0509006102  1
2005 Chen Z, Herman AE, Matos M, Mathis D, Benoist C. Where CD4+CD25+ T reg cells impinge on autoimmune diabetes. The Journal of Experimental Medicine. 202: 1387-97. PMID 16301745 DOI: 10.1084/Jem.20051409  1
2005 Chen Z, Benoist C, Mathis D. How defects in central tolerance impinge on a deficiency in regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 14735-40. PMID 16203996 DOI: 10.1073/Pnas.0507014102  1
2005 Maehr R, Mintern JD, Herman AE, Lennon-Duménil AM, Mathis D, Benoist C, Ploegh HL. Cathepsin L is essential for onset of autoimmune diabetes in NOD mice. The Journal of Clinical Investigation. 115: 2934-43. PMID 16184198 DOI: 10.1172/Jci25485  1
2005 Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C. Modifier loci condition autoimmunity provoked by Aire deficiency. The Journal of Experimental Medicine. 202: 805-15. PMID 16172259 DOI: 10.1084/Jem.20050693  1
2005 Ohmura K, Johnsen A, Ortiz-Lopez A, Desany P, Roy M, Besse W, Rogus J, Bogue M, Puech A, Lathrop M, Mathis D, Benoist C. Variation in IL-1beta gene expression is a major determinant of genetic differences in arthritis aggressivity in mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 12489-94. PMID 16113081 DOI: 10.1073/Pnas.0504325102  1
2005 Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. The cellular mechanism of Aire control of T cell tolerance. Immunity. 23: 227-39. PMID 16111640 DOI: 10.1016/J.Immuni.2005.07.005  1
2005 Shoda LK, Young DL, Ramanujan S, Whiting CC, Atkinson MA, Bluestone JA, Eisenbarth GS, Mathis D, Rossini AA, Campbell SE, Kahn R, Kreuwel HT. A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity. 23: 115-26. PMID 16111631 DOI: 10.1016/J.Immuni.2005.08.002  1
2005 Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. The Journal of Clinical Investigation. 115: 2454-61. PMID 16110329 DOI: 10.1172/Jci25048  1
2005 Ohmura K, Nguyen LT, Locksley RM, Mathis D, Benoist C. Interleukin-4 can be a key positive regulator of inflammatory arthritis. Arthritis and Rheumatism. 52: 1866-75. PMID 15934072 DOI: 10.1002/Art.21104  1
2005 Obst R, van Santen HM, Mathis D, Benoist C. Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response. The Journal of Experimental Medicine. 201: 1555-65. PMID 15897273 DOI: 10.1084/Jem.20042521  1
2005 Villaseñor J, Benoist C, Mathis D. AIRE and APECED: molecular insights into an autoimmune disease. Immunological Reviews. 204: 156-64. PMID 15790357 DOI: 10.1111/J.0105-2896.2005.00246.X  1
2005 Zucchelli S, Holler P, Yamagata T, Roy M, Benoist C, Mathis D. Defective central tolerance induction in NOD mice: genomics and genetics. Immunity. 22: 385-96. PMID 15780994 DOI: 10.1016/J.Immuni.2005.01.015  1
2005 Feuerer M, Benoist C, Mathis D. Green T(R) cells. Immunity. 22: 271-2. PMID 15780983 DOI: 10.1016/J.Immuni.2005.03.002  1
2005 Benoist C, Mathis D. Demystification of the alloresponse. Current Biology : Cb. 1: 143-4. PMID 15336148 DOI: 10.1016/0960-9822(91)90213-G  0.68
2005 Benoist C, Mathis D. The virtue of complexity. Current Biology : Cb. 3: 625-7. PMID 15335683 DOI: 10.1016/0960-9822(93)90015-G  0.8
2004 Goldrath AW, Luckey CJ, Park R, Benoist C, Mathis D. The molecular program induced in T cells undergoing homeostatic proliferation. Proceedings of the National Academy of Sciences of the United States of America. 101: 16885-90. PMID 15548615 DOI: 10.1073/Pnas.0407417101  1
2004 van Santen HM, Benoist C, Mathis D. Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells. The Journal of Experimental Medicine. 200: 1221-30. PMID 15534371 DOI: 10.1084/Jem.20041022  1
2004 Vence L, Benoist C, Mathis D. Fas deficiency prevents type 1 diabetes by inducing hyporesponsiveness in islet beta-cell-reactive T-cells. Diabetes. 53: 2797-803. PMID 15504959 DOI: 10.2337/Diabetes.53.11.2797  1
2004 Jacobs JP, Pettit AR, Shinohara ML, Jansson M, Cantor H, Gravallese EM, Mathis D, Benoist C. Lack of requirement of osteopontin for inflammation, bone erosion, and cartilage damage in the K/BxN model of autoantibody-mediated arthritis. Arthritis and Rheumatism. 50: 2685-94. PMID 15334485 DOI: 10.1002/Art.20381  1
2004 Matos M, Park R, Mathis D, Benoist C. Progression to islet destruction in a cyclophosphamide-induced transgenic model: a microarray overview. Diabetes. 53: 2310-21. PMID 15331540 DOI: 10.2337/Diabetes.53.9.2310  1
2004 Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R. Imaging inflammation of the pancreatic islets in type 1 diabetes. Proceedings of the National Academy of Sciences of the United States of America. 101: 12634-9. PMID 15304647 DOI: 10.1073/Pnas.0404307101  1
2004 Herman AE, Freeman GJ, Mathis D, Benoist C. CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. The Journal of Experimental Medicine. 199: 1479-89. PMID 15184501 DOI: 10.1084/Jem.20040179  1
2004 Mathis D, Benoist C. Back to central tolerance. Immunity. 20: 509-16. PMID 15142520 DOI: 10.1016/S1074-7613(04)00111-6  1
2004 Poirot L, Benoist C, Mathis D. Natural killer cells distinguish innocuous and destructive forms of pancreatic islet autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 101: 8102-7. PMID 15141080 DOI: 10.1073/Pnas.0402065101  1
2004 Yamagata T, Mathis D, Benoist C. Self-reactivity in thymic double-positive cells commits cells to a CD8 alpha alpha lineage with characteristics of innate immune cells. Nature Immunology. 5: 597-605. PMID 15133507 DOI: 10.1038/Ni1070  1
2004 Venanzi ES, Benoist C, Mathis D. Good riddance: Thymocyte clonal deletion prevents autoimmunity. Current Opinion in Immunology. 16: 197-202. PMID 15023413 DOI: 10.1016/J.Coi.2004.01.008  1
2004 Monach PA, Benoist C, Mathis D. The role of antibodies in mouse models of rheumatoid arthritis, and relevance to human disease. Advances in Immunology. 82: 217-48. PMID 14975258 DOI: 10.1016/S0065-2776(04)82005-4  1
2003 Martin-Orozco N, Chen Z, Poirot L, Hyatt E, Chen A, Kanagawa O, Sharpe A, Mathis D, Benoist C. Paradoxical dampening of anti-islet self-reactivity but promotion of diabetes by OX40 ligand. Journal of Immunology (Baltimore, Md. : 1950). 171: 6954-60. PMID 14662903 DOI: 10.4049/Jimmunol.171.12.6954  1
2003 Turley S, Poirot L, Hattori M, Benoist C, Mathis D. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. The Journal of Experimental Medicine. 198: 1527-37. PMID 14623908 DOI: 10.1084/Jem.20030966  1
2003 Stratmann T, Martin-Orozco N, Mallet-Designe V, Poirot L, McGavern D, Losyev G, Dobbs CM, Oldstone MB, Yoshida K, Kikutani H, Mathis D, Benoist C, Haskins K, Teyton L. Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity. The Journal of Clinical Investigation. 112: 902-14. PMID 12975475 DOI: 10.1172/Jci18337  1
2003 Matsumoto I, Lee DM, Goldbach-Mansky R, Sumida T, Hitchon CA, Schur PH, Anderson RJ, Coblyn JS, Weinblatt ME, Brenner M, Duclos B, Pasquali JL, El-Gabalawy H, Mathis D, Benoist C. Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders. Arthritis and Rheumatism. 48: 944-54. PMID 12687536 DOI: 10.1002/Art.10898  1
2003 Berzins SP, Venanzi ES, Benoist C, Mathis D. T-cell compartments of prediabetic NOD mice. Diabetes. 52: 327-34. PMID 12540604 DOI: 10.2337/Diabetes.52.2.327  1
2002 Benoist C, Mathis D. Mast cells in autoimmune disease. Nature. 420: 875-8. PMID 12490961 DOI: 10.1038/Nature01324  1
2002 Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science (New York, N.Y.). 298: 1395-401. PMID 12376594 DOI: 10.1126/Science.1075958  1
2002 Lee DM, Friend DS, Gurish MF, Benoist C, Mathis D, Brenner MB. Mast cells: a cellular link between autoantibodies and inflammatory arthritis. Science (New York, N.Y.). 297: 1689-92. PMID 12215644 DOI: 10.1126/Science.1073176  1
2002 Ji H, Pettit A, Ohmura K, Ortiz-Lopez A, Duchatelle V, Degott C, Gravallese E, Mathis D, Benoist C. Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis. The Journal of Experimental Medicine. 196: 77-85. PMID 12093872 DOI: 10.1084/Jem.20020439  1
2002 Goldrath AW, Sivakumar PV, Glaccum M, Kennedy MK, Bevan MJ, Benoist C, Mathis D, Butz EA. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. The Journal of Experimental Medicine. 195: 1515-22. PMID 12070279 DOI: 10.1084/Jem.20020033  1
2002 Maccioni M, Zeder-Lutz G, Huang H, Ebel C, Gerber P, Hergueux J, Marchal P, Duchatelle V, Degott C, van Regenmortel M, Benoist C, Mathis D. Arthritogenic monoclonal antibodies from K/BxN mice. The Journal of Experimental Medicine. 195: 1071-7. PMID 11956298 DOI: 10.1084/Jem.20011941  1
2002 Matsumoto I, Maccioni M, Lee DM, Maurice M, Simmons B, Brenner M, Mathis D, Benoist C. How antibodies to a ubiquitous cytoplasmic enzyme may provoke joint-specific autoimmune disease. Nature Immunology. 3: 360-5. PMID 11896391 DOI: 10.1038/Ni772  1
2002 Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, ... ... Mathis D, et al. Arthritis critically dependent on innate immune system players. Immunity. 16: 157-68. PMID 11869678 DOI: 10.1016/S1074-7613(02)00275-3  1
2002 Lafaille JJ, Mathis D. Immunological Yin-Yang Current Opinion in Immunology. 14: 741-743. DOI: 10.1016/S0952-7915(02)00412-0  0.52
2001 Mathis D, Vence L, Benoist C. beta-Cell death during progression to diabetes. Nature. 414: 792-8. PMID 11742411 DOI: 10.1038/414792A  1
2001 Gonzalez A, Andre-Schmutz I, Carnaud C, Mathis D, Benoist C. Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes. Nature Immunology. 2: 1117-25. PMID 11713466 DOI: 10.1038/Ni738  1
2001 Correia-Neves M, Mathis D, Benoist C. A molecular chart of thymocyte positive selection. European Journal of Immunology. 31: 2583-92. PMID 11536156 DOI: 10.1002/1521-4141(200109)31:9<2583::Aid-Immu2583>3.0.Co;2-Z  1
2001 Benoist C, Mathis D. Autoimmunity provoked by infection: how good is the case for T cell epitope mimicry? Nature Immunology. 2: 797-801. PMID 11526389 DOI: 10.1038/Ni0901-797  1
2001 Ji H, Gauguier D, Ohmura K, Gonzalez A, Duchatelle V, Danoy P, Garchon HJ, Degott C, Lathrop M, Benoist C, Mathis D. Genetic influences on the end-stage effector phase of arthritis. The Journal of Experimental Medicine. 194: 321-30. PMID 11489951 DOI: 10.1084/Jem.194.3.321  1
2001 Labrecque N, Whitfield LS, Obst R, Waltzinger C, Benoist C, Mathis D. How much TCR does a T cell need? Immunity. 15: 71-82. PMID 11485739 DOI: 10.1016/S1074-7613(01)00170-4  1
2001 Vivien L, Benoist C, Mathis D. T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo. International Immunology. 13: 763-8. PMID 11369703 DOI: 10.1093/Intimm/13.6.763  1
2001 Correia-Neves M, Waltzinger C, Mathis D, Benoist C. The shaping of the T cell repertoire. Immunity. 14: 21-32. PMID 11163227 DOI: 10.1016/S1074-7613(01)00086-3  1
2000 Benoist C, Mathis D. A revival of the B cell paradigm for rheumatoid arthritis pathogenesis? Arthritis Research. 2: 90-4. PMID 11094418 DOI: 10.1186/ar73  1
2000 Leenders H, Whiffield S, Benoist C, Mathis D. Role of the forkhead transcription family member, FKHR, in thymocyte differentiation. European Journal of Immunology. 30: 2980-90. PMID 11069081 DOI: 10.1002/1521-4141(200010)30:10<2980::Aid-Immu2980>3.0.Co;2-9  1
2000 van Santen H, Benoist C, Mathis D. A cassette vector for high-level reporter expression driven by a hybrid invariant chain promoter in transgenic mice. Journal of Immunological Methods. 245: 133-7. PMID 11042290 DOI: 10.1016/S0022-1759(00)00276-3  1
2000 Luhder F, Chambers C, Allison JP, Benoist C, Mathis D. Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 12204-9. PMID 11035773 DOI: 10.1073/Pnas.200348397  1
2000 Rooke R, Benoist C, Mathis D. Intrathymic delivery of MHC genes using recombinant adenoviruses. Methods in Molecular Biology (Clifton, N.J.). 134: 69-79. PMID 10730250 DOI: 10.1385/1-59259-682-7:69  1
2000 Witherden D, van Oers N, Waltzinger C, Weiss A, Benoist C, Mathis D. Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. The Journal of Experimental Medicine. 191: 355-64. PMID 10637279 DOI: 10.1084/Jem.191.2.355  1
1999 Mangialaio S, Ji H, Korganow AS, Kouskoff V, Benoist C, Mathis D. The arthritogenic T cell receptor and its ligand in a model of spontaneous arthritis. Arthritis and Rheumatism. 42: 2517-23. PMID 10615996 DOI: 10.1002/1529-0131(199912)42:12<2517::Aid-Anr3>3.0.Co;2-W  1
1999 Labrecque N, Madsen L, Fugger L, Benoist C, Mathis D. Toxic MHC class II beta chains. Immunity. 11: 515-6. PMID 10591176 DOI: 10.1016/S1074-7613(00)80126-0  1
1999 Chan S, Waltzinger C, Tarakhovsky A, Benoist C, Mathis D. An influence of CD5 on the selection of CD4-lineage T cells. European Journal of Immunology. 29: 2916-22. PMID 10508266 DOI: 10.1002/(Sici)1521-4141(199909)29:09<2916::Aid-Immu2916>3.0.Co;2-I  1
1999 Rooke R, Waltzinger C, Benoist C, Mathis D. Positive selection of thymocytes induced by gene transfer: MHC class II-mediated selection of CD8 lineage cells. International Immunology. 11: 1595-600. PMID 10508177 DOI: 10.1093/Intimm/11.10.1595  1
1999 Benoist C, Mathis D. Spotting a killer's target in autoimmune diabetes. Nature Medicine. 5: 992-3. PMID 10470072 DOI: 10.1038/12428  1
1999 Madsen L, Labrecque N, Engberg J, Dierich A, Svejgaard A, Benoist C, Mathis D, Fugger L. Mice lacking all conventional MHC class II genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 10338-43. PMID 10468609 DOI: 10.1073/Pnas.96.18.10338  1
1999 Ji H, Korganow AS, Mangialaio S, Höglund P, André I, Lühder F, Gonzalez A, Poirot L, Benoist C, Mathis D. Different modes of pathogenesis in T-cell-dependent autoimmunity: clues from two TCR transgenic systems. Immunological Reviews. 169: 139-46. PMID 10450514 DOI: 10.1111/J.1600-065X.1999.Tb01312.X  1
1999 Korganow AS, Ji H, Mangialaio S, Duchatelle V, Pelanda R, Martin T, Degott C, Kikutani H, Rajewsky K, Pasquali JL, Benoist C, Mathis D. From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins. Immunity. 10: 451-61. PMID 10229188 DOI: 10.1016/S1074-7613(00)80045-X  1
1999 Tourne S, Kouskoff V, Ho W, Davis M, Benoist C, Mathis D. Inhibition of thymocyte positive selection by natural MHC: peptide ligands. European Journal of Immunology. 29: 394-402. PMID 10064054 DOI: 10.1002/(Sici)1521-4141(199902)29:02<394::Aid-Immu394>3.0.Co;2-2  1
1999 Benoist C, Mathis D. T-cell development: a new marker of differentiation state. Current Biology : Cb. 9: R59-61. PMID 10021359 DOI: 10.1016/S0960-9822(99)80011-6  1
1999 André-Schmutz I, Hindelang C, Benoist C, Mathis D. Cellular and molecular changes accompanying the progression from insulitis to diabetes. European Journal of Immunology. 29: 245-55. PMID 9933106 DOI: 10.1002/(Sici)1521-4141(199901)29:01<245::Aid-Immu245>3.0.Co;2-O  1
1999 Höglund P, Mintern J, Waltzinger C, Heath W, Benoist C, Mathis D. Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes. The Journal of Experimental Medicine. 189: 331-9. PMID 9892615 DOI: 10.1084/Jem.189.2.331  1
1998 Williams GS, Malin M, Vremec D, Chang CH, Boyd R, Benoist C, Mathis D. Mice lacking the transcription factor CIITA--a second look. International Immunology. 10: 1957-67. PMID 9885917 DOI: 10.1093/Intimm/10.12.1957  1
1998 Chan S, Correia-Neves M, Dierich A, Benoist C, Mathis D. Visualization of CD4/CD8 T cell commitment. The Journal of Experimental Medicine. 188: 2321-33. PMID 9858518 DOI: 10.1084/Jem.188.12.2321  1
1998 Chan S, Correia-Neves M, Benoist C, Mathis D. CD4/CD8 lineage commitment: matching fate with competence. Immunological Reviews. 165: 195-207. PMID 9850862 DOI: 10.1111/J.1600-065X.1998.Tb01240.X  1
1998 Williams GS, Oxenius A, Hengartner H, Benoist C, Mathis D. CD4+ T cell responses in mice lacking MHC class II molecules specifically on B cells. European Journal of Immunology. 28: 3763-72. PMID 9842919 DOI: 10.1002/(Sici)1521-4141(199811)28:11<3763::Aid-Immu3763>3.0.Co;2-D  1
1998 Wolf PR, Tourne S, Miyazaki T, Benoist C, Mathis D, Ploegh HL. The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed. European Journal of Immunology. 28: 2605-18. PMID 9754549 DOI: 10.1002/(Sici)1521-4141(199809)28:09<2605::Aid-Immu2605>3.0.Co;2-B  1
1998 Wang B, Gonzalez A, Höglund P, Katz JD, Benoist C, Mathis D. Interleukin-4 deficiency does not exacerbate disease in NOD mice. Diabetes. 47: 1207-11. PMID 9703318 DOI: 10.2337/Diab.47.8.1207  1
1998 Benoist C, Mathis D. Autoimmunity. The pathogen connection. Nature. 394: 227-8. PMID 9685154 DOI: 10.1038/28282  1
1998 Lühder F, Höglund P, Allison JP, Benoist C, Mathis D. Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) regulates the unfolding of autoimmune diabetes. The Journal of Experimental Medicine. 187: 427-32. PMID 9449722 DOI: 10.1084/Jem.187.3.427  1
1998 Lühder F, Katz J, Benoist C, Mathis D. Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities. The Journal of Experimental Medicine. 187: 379-87. PMID 9449718 DOI: 10.1084/Jem.187.3.379  1
1998 Mathis D. Nucleotide Sequence: Correction Science. 279: 151b-151. DOI: 10.1126/Science.279.5348.151B  0.56
1997 Gonzalez A, Katz JD, Mattei MG, Kikutani H, Benoist C, Mathis D. Genetic control of diabetes progression. Immunity. 7: 873-83. PMID 9430232 DOI: 10.1016/S1074-7613(00)80405-7  1
1997 Wang B, André I, Gonzalez A, Katz JD, Aguet M, Benoist C, Mathis D. Interferon-gamma impacts at multiple points during the progression of autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. 94: 13844-9. PMID 9391115 DOI: 10.1073/Pnas.94.25.13844  1
1997 Tourne S, Miyazaki T, Oxenius A, Klein L, Fehr T, Kyewski B, Benoist C, Mathis D. Selection of a broad repertoire of CD4+ T cells in H-2Ma0/0 mice. Immunity. 7: 187-95. PMID 9285404 DOI: 10.1016/S1074-7613(00)80522-1  1
1997 Benoist C, Mathis D. Autoimmune diabetes. Retrovirus as trigger, precipitator or marker? Nature. 388: 833-4. PMID 9278041 DOI: 10.1038/42145  1
1997 Tourne S, Miyazaki T, Wolf P, Ploegh H, Benoist C, Mathis D. Functionality of major histocompatibility complex class II molecules in mice doubly deficient for invariant chain and H-2M complexes. Proceedings of the National Academy of Sciences of the United States of America. 94: 9255-60. PMID 9256469 DOI: 10.1073/Pnas.94.17.9255  1
1997 Rooke R, Waltzinger C, Benoist C, Mathis D. Targeted complementation of MHC class II deficiency by intrathymic delivery of recombinant adenoviruses. Immunity. 7: 123-34. PMID 9252125 DOI: 10.1016/S1074-7613(00)80515-4  1
1997 Benoist C, Mathis D. Selection for survival? Science (New York, N.Y.). 276: 2000-1. PMID 9221508 DOI: 10.1126/Science.276.5321.2000  1
1997 Benoist C, Mathis D. Positive selection of T cells: fastidious or promiscuous? Current Opinion in Immunology. 9: 245-9. PMID 9099801 DOI: 10.1016/S0952-7915(97)80143-4  1
1997 Benoist C, Mathis D. Cell death mediators in autoimmune diabetes--no shortage of suspects. Cell. 89: 1-3. PMID 9094706 DOI: 10.1016/S0092-8674(00)80174-9  1
1997 Nakano N, Rooke R, Benoist C, Mathis D. Positive selection of T cells induced by viral delivery of neopeptides to the thymus. Science (New York, N.Y.). 275: 678-83. PMID 9005856 DOI: 10.1126/Science.275.5300.678  1
1997 Correia Neves M, Benoist C, Mathis D. Differential usage of Vα2 family members by CD4+ and CD8+ T cells Immunology Letters. 56: 347. DOI: 10.1016/S0165-2478(97)86404-8  0.4
1997 Bodmer H, Chan S, Benoist C, Mathis D. EAE susceptibility reduced but not abrogated by transgene expression of an encephalitogenic MBP epitope in MHC class II positive cells Immunology Letters. 56: 220. DOI: 10.1016/S0165-2478(97)85877-4  0.44
1997 Stuart Williams G, Benoist C, Mathis D. Mice with MHC class II− B cells Immunology Letters. 56: 203. DOI: 10.1016/S0165-2478(97)85812-9  0.52
1997 Witherden D, Benoist C, Mathis D. Tetracycline inducible MHC class II and class I expression Immunology Letters. 56: 84-85. DOI: 10.1016/S0165-2478(97)85329-1  0.56
1996 Kouskoff V, Korganow AS, Duchatelle V, Degott C, Benoist C, Mathis D. Organ-specific disease provoked by systemic autoimmunity. Cell. 87: 811-22. PMID 8945509 DOI: 10.1016/S0092-8674(00)81989-3  1
1996 Texidó G, Jacobs H, Meiering M, Kühn R, Roes J, Müller W, Gilfillan S, Fujiwara H, Kikutani H, Yoshida N, Amakawa R, Benoist C, Mathis D, Kishimoto T, Mak TW, et al. Somatic hypermutation occurs in B cells of terminal deoxynucleotidyl transferase-, CD23-, interleukin-4-, IgD- and CD30-deficient mouse mutants. European Journal of Immunology. 26: 1966-9. PMID 8765046 DOI: 10.1002/Eji.1830260843  1
1996 Wang B, Gonzalez A, Benoist C, Mathis D. The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus. European Journal of Immunology. 26: 1762-9. PMID 8765018 DOI: 10.1002/Eji.1830260815  1
1996 Wang B, Benoist C, Mathis D. The immunosuppressant 15-deoxyspergualin [correction of 1,5-deoxyspergualin] reveals commonality between preT and preB cell differentiation. The Journal of Experimental Medicine. 183: 2427-36. PMID 8676063 DOI: 10.1084/Jem.183.6.2427  1
1996 Miyazaki T, Dierich A, Benoist C, Mathis D. LAG-3 is not responsible for selecting T helper cells in CD4-deficient mice. International Immunology. 8: 725-9. PMID 8671660 DOI: 10.1093/Intimm/8.5.725  1
1996 Tourne S, van Santen HM, van Roon M, Berns A, Benoist C, Mathis D, Ploegh H. Biosynthesis of major histocompatibility complex molecules and generation of T cells in Ii TAP1 double-mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 93: 1464-9. PMID 8643655 DOI: 10.1073/Pnas.93.4.1464  1
1996 André I, Gonzalez A, Wang B, Katz J, Benoist C, Mathis D. Checkpoints in the progression of autoimmune disease: lessons from diabetes models. Proceedings of the National Academy of Sciences of the United States of America. 93: 2260-3. PMID 8637860 DOI: 10.1073/Pnas.93.6.2260  1
1996 Miyazaki T, Dierich A, Benoist C, Mathis D. Independent modes of natural killing distinguished in mice lacking Lag3. Science (New York, N.Y.). 272: 405-8. PMID 8602528 DOI: 10.1126/Science.272.5260.405  1
1996 Miyazaki T, Wolf P, Tourne S, Waltzinger C, Dierich A, Barois N, Ploegh H, Benoist C, Mathis D. Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway. Cell. 84: 531-41. PMID 8598040 DOI: 10.1016/S0092-8674(00)81029-6  1
1996 Battegay M, Bachmann MF, Burhkart C, Viville S, Benoist C, Mathis D, Hengartner H, Zinkernagel RM. Antiviral immune responses of mice lacking MHC class II or its associated invariant chain. Cellular Immunology. 167: 115-21. PMID 8548834 DOI: 10.1006/Cimm.1996.0014  1
1995 Cheroutre H, Holcombe HR, Tangri S, Castaño AR, Teitell M, Miller JE, Cardell S, Benoist C, Mathis D, Huse WD. Antigen-presenting function of the TL antigen and mouse CD1 molecules. Immunological Reviews. 147: 31-52. PMID 8847078 DOI: 10.1111/J.1600-065X.1995.Tb00086.X  1
1995 Gilfillan S, Benoist C, Mathis D. Mice lacking terminal deoxynucleotidyl transferase: adult mice with a fetal antigen receptor repertoire. Immunological Reviews. 148: 201-19. PMID 8825288 DOI: 10.1111/J.1600-065X.1995.Tb00099.X  1
1995 Kouskoff V, Vonesch JL, Benoist C, Mathis D. The influence of positive selection on RAG expression in thymocytes. European Journal of Immunology. 25: 54-8. PMID 7843253 DOI: 10.1002/Eji.1830250111  1
1995 Katz JD, Benoist C, Mathis D. T helper cell subsets in insulin-dependent diabetes. Science (New York, N.Y.). 268: 1185-8. PMID 7761837 DOI: 10.1126/Science.7761837  1
1995 Kouskoff V, Signorelli K, Benoist C, Mathis D. Cassette vectors directing expression of T cell receptor genes in transgenic mice. Journal of Immunological Methods. 180: 273-80. PMID 7714342 DOI: 10.1016/0022-1759(95)00002-R  1
1995 Tourne S, Nakano N, Viville S, Benoist C, Mathis D. The influence of invariant chain on the positive selection of single T cell receptor specificities. European Journal of Immunology. 25: 1851-6. PMID 7621862 DOI: 10.1002/Eji.1830250709  1
1995 Cardell S, Tangri S, Chan S, Kronenberg M, Benoist C, Mathis D. CD1-restricted CD4+ T cells in major histocompatibility complex class II-deficient mice. The Journal of Experimental Medicine. 182: 993-1004. PMID 7561702 DOI: 10.1084/Jem.182.4.993  1
1995 Gilfillan S, Bachmann M, Trembleau S, Adorini L, Kalinke U, Zinkernagel R, Benoist C, Mathis D. Efficient immune responses in mice lacking N-region diversity. European Journal of Immunology. 25: 3115-22. PMID 7489751 DOI: 10.1002/Eji.1830251119  1
1994 Benoist C, Mathis D. Transgenes and knock-outs in autoimmunity. Current Opinion in Immunology. 5: 900-2. PMID 8297522 DOI: 10.1016/0952-7915(93)90103-Y  0.72
1994 Chan SH, Benoist C, Mathis D. A challenge to the instructive model of positive selection. Immunological Reviews. 135: 119-31. PMID 8282310 DOI: 10.1111/J.1600-065X.1993.Tb00646.X  0.48
1994 Katz J, Benoist C, Mathis D. Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice. European Journal of Immunology. 23: 3358-60. PMID 8258349 DOI: 10.1002/Eji.1830231244  0.4
1994 Chan SH, Benoist C, Mathis D. In favor of the selective model of positive selection. Seminars in Immunology. 6: 241-8. PMID 8000033 DOI: 10.1006/Smim.1994.1031  1
1994 Merkenschlager M, Benoist C, Mathis D. Evidence for a single-niche model of positive selection. Proceedings of the National Academy of Sciences of the United States of America. 91: 11694-8. PMID 7972126 DOI: 10.1073/Pnas.91.24.11694  1
1994 Gilfillan S, Waltzinger C, Benoist C, Mathis D. More efficient positive selection of thymocytes in mice lacking terminal deoxynucleotidyl transferase. International Immunology. 6: 1681-6. PMID 7865461 DOI: 10.1093/Intimm/6.11.1681  1
1994 Benoist C, Mathis D. T-cell co-receptors. The end of a frustrating search. Current Biology : Cb. 4: 821-3. PMID 7865025 DOI: 10.1016/S0960-9822(00)00182-2  1
1994 Bodmer H, Viville S, Benoist C, Mathis D. Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain. Science (New York, N.Y.). 263: 1284-6. PMID 7510069 DOI: 10.1126/Science.7510069  1
1994 Cardell S, Merkenschlager M, Bodmer H, Chan S, Cosgrove D, Benoist C, Mathis D. The immune system of mice lacking conventional MHC class II molecules. Advances in Immunology. 55: 423-40. PMID 7508177 DOI: 10.1016/S0065-2776(08)60515-5  1
1994 Chan S, Waltzinger C, Baron A, Benoist C, Mathis D. Role of coreceptors in positive selection and lineage commitment. The Embo Journal. 13: 4482-4489. DOI: 10.1002/J.1460-2075.1994.Tb06770.X  0.4
1993 Bogue M, Mossmann H, Stauffer U, Benoist C, Mathis D. The level of N-region diversity in T cell receptors is not pre-ordained in the stem cell. European Journal of Immunology. 23: 1185-8. PMID 8477813 DOI: 10.1002/Eji.1830230533  0.64
1993 Katz JD, Wang B, Haskins K, Benoist C, Mathis D. Following a diabetogenic T cell from genesis through pathogenesis. Cell. 74: 1089-100. PMID 8402882 DOI: 10.1016/0092-8674(93)90730-E  1
1993 Gilfillan S, Dierich A, Lemeur M, Benoist C, Mathis D. Mice lacking TdT: mature animals with an immature lymphocyte repertoire. Science (New York, N.Y.). 261: 1175-8. PMID 8356452 DOI: 10.1126/Science.8356452  0.56
1993 Bodmer H, Obert G, Chan S, Benoist C, Mathis D. Environmental modulation of the autonomy of cytotoxic T lymphocytes. European Journal of Immunology. 23: 1649-54. PMID 8325339 DOI: 10.1002/Eji.1830230738  0.48
1993 Mathis D, Benoist C. T cell receptor specificity and diabetes in nonobese diabetic mice. Science (New York, N.Y.). 262: 1583; author reply 1. PMID 8248810 DOI: 10.1126/Science.8248810  1
1993 Dierich A, Chan SH, Benoist C, Mathis D. Graft rejection by T cells not restricted by conventional major histocompatibility complex molecules. European Journal of Immunology. 23: 2725-8. PMID 8104801 DOI: 10.1002/Eji.1830231055  0.32
1993 Chan SH, Cosgrove D, Waltzinger C, Benoist C, Mathis D. Another view of the selective model of thymocyte selection. Cell. 73: 225-36. PMID 8097430 DOI: 10.1016/0092-8674(93)90225-F  0.6
1993 Viville S, Neefjes J, Lotteau V, Dierich A, Lemeur M, Ploegh H, Benoist C, Mathis D. Mice lacking the MHC class II-associated invariant chain. Cell. 72: 635-48. PMID 7679955 DOI: 10.1016/0092-8674(93)90081-Z  1
1993 Kouskoff V, Fehling HJ, Lemeur M, Benoist C, Mathis D. A vector driving the expression of foreign cDNAs in the MHC class II-positive cells of transgenic mice. Journal of Immunological Methods. 166: 287-91. PMID 7507147 DOI: 10.1016/0022-1759(93)90370-M  1
1992 Li XY, Mantovani R, Hooft van Huijsduijnen R, Andre I, Benoist C, Mathis D. Evolutionary variation of the CCAAT-binding transcription factor NF-Y. Nucleic Acids Research. 20: 1087-91. PMID 1549471 DOI: 10.1093/Nar/20.5.1087  1
1992 Benoist C, Mathis D. Generation of the alpha beta T-cell repertoire. Current Opinion in Immunology. 4: 156-61. PMID 1534989 DOI: 10.1016/0952-7915(92)90005-Y  0.72
1992 Cosgrove D, Bodmer H, Bogue M, Benoist C, Mathis D. Evaluation of the functional equivalence of major histocompatibility complex class II A and E complexes. The Journal of Experimental Medicine. 176: 629-34. PMID 1500864 DOI: 10.1084/Jem.176.2.629  0.4
1992 Bogue M, Gilfillan S, Benoist C, Mathis D. Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny. Proceedings of the National Academy of Sciences of the United States of America. 89: 11011-5. PMID 1438306 DOI: 10.1073/Pnas.89.22.11011  0.56
1992 Cosgrove D, Chan SH, Waltzinger C, Benoist C, Mathis D. The thymic compartment responsible for positive selection of CD4+ T cells. International Immunology. 4: 707-10. PMID 1352128 DOI: 10.1093/Intimm/4.6.707  0.52
1992 Signorelli K, Benoist C, Mathis D. Why is clonal deletion of neonatal thymocytes defective? European Journal of Immunology. 22: 2487-93. PMID 1327799 DOI: 10.1002/Eji.1830221004  0.72
1992 Benoist C, Mathis D. Generation of the α β T-cell repertoire Current Biology. 2: 308. DOI: 10.1016/0960-9822(92)90883-C  0.6
1992 Mantovani R, Pessara U, Tronche F, Li X, Knapp A, Pasquali J, Benoist C, Mathis D. Monoclonal antibodies to NF-Y define its function in MHC class II and albumin gene transcription. The Embo Journal. 11: 3315-3322. DOI: 10.1002/J.1460-2075.1992.Tb05410.X  0.36
1991 Candeias S, Katz J, Benoist C, Mathis D, Haskins K. Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors Proceedings of the National Academy of Sciences of the United States of America. 88: 6167-6170. PMID 2068098 DOI: 10.1073/Pnas.88.14.6167  1
1991 Candéias S, Waltzinger C, Benoist C, Mathis D. The V beta 17+ T cell repertoire: skewed J beta usage after thymic selection; dissimilar CDR3s in CD4+ versus CD8+ cells. The Journal of Experimental Medicine. 174: 989-1000. PMID 1940807 DOI: 10.1084/Jem.174.5.989  0.68
1991 Wei BY, Gervois N, Mer G, Adorini L, Benoist C, Mathis D. Local structure of a peptide contact site on a(Formula presented) International Immunology. 3: 833-837. PMID 1911551 DOI: 10.1093/Intimm/3.8.833  1
1991 Cosgrove D, Gray D, Dierich A, Kaufman J, Lemeur M, Benoist C, Mathis D. Mice lacking MHC class II molecules. Cell. 66: 1051-66. PMID 1909605 DOI: 10.1016/0092-8674(91)90448-8  0.36
1991 Bogue M, Candéias S, Benoist C, Mathis D. A special repertoire of alpha:beta T cells in neonatal mice. The Embo Journal. 10: 3647-3654. DOI: 10.1002/J.1460-2075.1991.Tb04931.X  0.48
1990 Dellabona P, Peccoud J, Benoist C, Mathis D. T-cell recognition of superantigens: inside or outside the groove? Cold Spring Harbor Symposia On Quantitative Biology. 375-81. PMID 2639759 DOI: 10.1101/Sqb.1989.054.01.046  0.68
1990 Benoist C, Mathis D. Sperm cells as vectors for transferring DNA into mouse eggs: a breakthrough for immunologists? Immunology Today. 10: 369. PMID 2610852 DOI: 10.1016/0167-5699(89)90269-7  0.8
1990 Dellabona P, Peccoud J, Kappler J, Marrack P, Benoist C, Mathis D. Superantigens interact with MHC class II molecules outside of the antigen groove. Cell. 62: 1115-21. PMID 2401011 DOI: 10.1016/0092-8674(90)90388-U  0.36
1990 Böhme J, Schuhbaur B, Kanagawa O, Benoist C, Mathis D. MHC-linked protection from diabetes dissociated from clonal deletion of T cells. Science (New York, N.Y.). 249: 293-5. PMID 2115690 DOI: 10.1126/Science.2115690  0.32
1990 Benoist C, Mathis D. Regulation of major histocompatibility complex class-II genes: X, Y and other letters of the alphabet. Annual Review of Immunology. 8: 681-715. PMID 2111709 DOI: 10.1146/Annurev.Iy.08.040190.003341  0.68
1990 Peccoud J, Dellabona P, Allen P, Benoist C, Mathis D. Delineation of antigen contact residues on an MHC class II molecule. The Embo Journal. 9: 4215-4223. DOI: 10.1002/J.1460-2075.1990.Tb07869.X  0.52
1990 Warren AP, Paschedag I, Benoist C, Peccoud J, Mathis D, Thomas DB. Defects in antigen presentation of mutant influenza haemagglutinins are reversed by mutations in the MHC class II molecule. The Embo Journal. 9: 3849-3856. DOI: 10.1002/J.1460-2075.1990.Tb07603.X  0.32
1989 Gerber P, Lang G, Dorn A, Fehling J, Garcin G, Koch W, Waltzinger C, Benoist C, Mathis D. The enhancer in an MHC class II gene, in vitro and in mouso. Biochimie. 70: 919-25. PMID 2905173 DOI: 10.1016/0300-9084(88)90233-7  0.36
1989 Fehling HJ, Viville S, van Ewijk W, Benoist C, Mathis D. Fine-tuning of MHC class II gene expression in defined microenvironments. Trends in Genetics : Tig. 5: 342-7. PMID 2692242 DOI: 10.1016/0168-9525(89)90140-6  1
1989 Dorn A, Benoist C, Mathis D. New B-lymphocyte-specific enhancer-binding protein. Molecular and Cellular Biology. 9: 312-20. PMID 2564635 DOI: 10.1128/Mcb.9.1.312  0.4
1989 Benoist C, Mathis D. Positive selection of the T cell repertoire: where and when does it occur? Cell. 58: 1027-33. PMID 2505933 DOI: 10.1016/0092-8674(89)90501-1  0.68
1989 Bohme J, Haskins K, Stecha P, Van Ewijk W, LeMeur M, Gerlinger P, Benoist C, Mathis D. Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant Science. 244: 1179-183. PMID 2499048 DOI: 10.1126/Science.2499048  1
1989 Berg LJ, Pullen AM, Fazekas de St Groth B, Mathis D, Benoist C, Davis MM. Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand. Cell. 58: 1035-46. PMID 2476238 DOI: 10.1016/0092-8674(89)90502-3  1
1989 Pierres M, Marchetto S, Naquet P, Landais D, Peccoud J, Benoist C, Mathis D. I-A alpha polymorphic residues that determine alloreactive T cell recognition. The Journal of Experimental Medicine. 169: 1655-68. PMID 2469763 DOI: 10.1084/Jem.169.5.1655  0.44
1989 Koch W, Benoist C, Mathis D. Anatomy of a new B-cell-specific enhancer. Molecular and Cellular Biology. 9: 303-11. PMID 2467189 DOI: 10.1128/Mcb.9.1.303  0.32
1988 van Ewijk W, Ron Y, Monaco J, Kappler J, Marrack P, Le Meur M, Gerlinger P, Durand B, Benoist C, Mathis D. Compartmentalization of MHC class II gene expression in transgenic mice. Cell. 53: 357-70. PMID 3259162 DOI: 10.1016/0092-8674(88)90156-0  0.32
1988 Dorn A, Fehling HJ, Koch W, Le Meur M, Gerlinger P, Benoist C, Mathis D. B-cell control region at the 5' end of a major histocompatibility complex class II gene: sequences and factors. Molecular and Cellular Biology. 8: 3975-87. PMID 3141781 DOI: 10.1128/Mcb.8.10.3975  1
1988 Koch W, Candeias S, Guardiola J, Accolla R, Benoist C, Mathis D. An enhancer factor defect in a mutant Burkitt lymphoma cell line. The Journal of Experimental Medicine. 167: 1781-90. PMID 3133441 DOI: 10.1084/Jem.167.6.1781  1
1987 Hooft van Huijsduijnen RA, Bollekens J, Dorn A, Benoist C, Mathis D. Properties of a CCAAT box-binding protein. Nucleic Acids Research. 15: 7265-82. PMID 3477778 DOI: 10.1093/Nar/15.18.7265  0.36
1987 Dorn A, Bollekens J, Staub A, Benoist C, Mathis D. A multiplicity of CCAAT box-binding proteins. Cell. 50: 863-72. PMID 3476205 DOI: 10.1016/0092-8674(87)90513-7  0.36
1987 Dorn A, Durand B, Marfing C, Le Meur M, Benoist C, Mathis D. Conserved major histocompatibility complex class II boxes--X and Y--are transcriptional control elements and specifically bind nuclear proteins. Proceedings of the National Academy of Sciences of the United States of America. 84: 6249-53. PMID 3114745 DOI: 10.1073/Pnas.84.17.6249  0.52
1986 Landais D, Waltzinger C, Beck BN, Staub A, McKean DJ, Benoist C, Mathis D. Functional sites on la molecules: A molecular dissection of Aα immunogenicity Cell. 47: 173-181. PMID 2429774 DOI: 10.1016/0092-8674(86)90440-X  1
1985 Le Meur M, Gerlinger P, Benoist C, Mathis D. Correcting an immune-response deficiency by creating E alpha gene transgenic mice. Nature. 316: 38-42. PMID 3925351 DOI: 10.1038/316038A0  0.4
1985 Landais D, Matthes H, Benoist C, Mathis D. A molecular basis for the Ia.2 and Ia.19 antigenic determinants Proceedings of the National Academy of Sciences of the United States of America. 82: 2930-2934. PMID 2581258 DOI: 10.1073/Pnas.82.9.2930  1
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