Chinnaswamy Tiruppathi - Publications

Affiliations: 
University of Illinois at Chicago, Health Sciences Center 
Area:
Pharmacology, Cell Biology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Tiruppathi C, Regmi SC, Wang DM, Mo GCH, Toth PT, Vogel SM, Stan RV, Henkemeyer M, Minshall RD, Rehman J, Malik AB. EphB1 Interaction with Caveolin-1 in Endothelial Cells Modulates Caveolae Biogenesis. Molecular Biology of the Cell. mbcE19120713. PMID 32238105 DOI: 10.1091/Mbc.E19-12-0713  0.48
2019 Nepal S, Tiruppathi C, Tsukasaki Y, Farahany J, Mittal M, Rehman J, Prockop DJ, Malik AB. STAT6 induces expression of Gas6 in macrophages to clear apoptotic neutrophils and resolve inflammation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31363052 DOI: 10.1073/Pnas.1821601116  0.48
2017 Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Tiruppathi C, Malik AB, Rehman J. Response by Mittal et al to Letter Regarding Article, "Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury". Circulation Research. 121: e87. PMID 29217714 DOI: 10.1161/Circresaha.117.312146  0.48
2017 Mittal M, Nepal S, Tsukasaki Y, Hecquet CM, Soni D, Rehman J, Tiruppathi C, Malik AB. Neutrophil Activation of Endothelial Cell-Expressed TRPM2 Mediates Transendothelial Neutrophil Migration and Vascular Injury. Circulation Research. PMID 28790198 DOI: 10.1161/Circresaha.117.311747  0.48
2017 Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd JE, Austin ED, Machado RF, Minshall RD, Rehman J, Malik AB. Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension. Molecular Biology of the Cell. 28: 1177-1185. PMID 28468941 DOI: 10.1091/mbc.E16-11-0790  0.48
2017 Soni D, Regmi SC, Wang DM, DebRoy A, Zhao YY, Vogel SM, Malik AB, Tiruppathi C. Pyk2 Phosphorylation of VE-PTP Downstream of STIM1 induced Ca2+ entry Regulates Disassembly of Adherens Junctions. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00008.2017. PMID 28385807 DOI: 10.1152/Ajplung.00008.2017  0.48
2017 Marsboom G, Chen Z, Yuan Y, Zhang Y, Tiruppathi C, Loyd JE, Austin ED, Machado RF, Minshall RD, Rehman J, Malik AB. Aberrant Caveolin-1-Mediated Smad Signaling and Proliferation Identified by Analysis of Adenine 474 Deletion Mutation (c.474delA) in Patient Fibroblasts: A New Perspective in the Mechanism of Pulmonary Hypertension. Molecular Biology of the Cell. PMID 28298490 DOI: 10.1091/Mbc.E16-06-0380  0.48
2016 Mittal M, Tiruppathi C, Nepal S, Zhao YY, Grzych D, Soni D, Prockop DJ, Malik AB. TNFα-stimulated gene-6 (TSG6) activates macrophage phenotype transition to prevent inflammatory lung injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911817 DOI: 10.1073/Pnas.1614935113  0.48
2016 Wang G, Cao L, Liu X, Sieracki NA, Di A, Wen X, Chen Y, Taylor S, Huang X, Tiruppathi C, Zhao YY, Song Y, Gao X, Jin T, Bai C, et al. Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation. Developmental Cell. PMID 27569419 DOI: 10.1016/J.Devcel.2016.07.014  0.48
2016 Zimnicka AM, Husain YS, Shajahan AN, Sverdlov M, Chaga O, Chen Z, Toth PT, Klomp J, Karginov AV, Tiruppathi C, Malik AB, Minshall RD. Src-dependent phosphorylation of caveolin-1 Tyr14 promotes swelling and release of caveolae. Molecular Biology of the Cell. PMID 27170175 DOI: 10.1091/Mbc.E15-11-0756  0.48
2014 DebRoy A, Vogel SM, Soni D, Sundivakkam PC, Malik AB, Tiruppathi C. Cooperative signaling via transcription factors NF-κB and AP1/c-Fos mediates endothelial cell STIM1 expression and hyperpermeability in response to endotoxin. The Journal of Biological Chemistry. 289: 24188-201. PMID 25016017 DOI: 10.1074/Jbc.M114.570051  0.48
2014 Tiruppathi C, Soni D, Wang DM, Xue J, Singh V, Thippegowda PB, Cheppudira BP, Mishra RK, Debroy A, Qian Z, Bachmaier K, Zhao YY, Christman JW, Vogel SM, Ma A, et al. The transcription factor DREAM represses the deubiquitinase A20 and mediates inflammation. Nature Immunology. 15: 239-47. PMID 24487321 DOI: 10.1038/Ni.2823  0.48
2013 Sundivakkam PC, Natarajan V, Malik AB, Tiruppathi C. Store-operated Ca2+ entry (SOCE) induced by protease-activated receptor-1 mediates STIM1 protein phosphorylation to inhibit SOCE in endothelial cells through AMP-activated protein kinase and p38β mitogen-activated protein kinase. The Journal of Biological Chemistry. 288: 17030-41. PMID 23625915 DOI: 10.1074/Jbc.M112.411272  0.48
2012 Sundivakkam PC, Freichel M, Singh V, Yuan JP, Vogel SM, Flockerzi V, Malik AB, Tiruppathi C. The Ca(2+) sensor stromal interaction molecule 1 (STIM1) is necessary and sufficient for the store-operated Ca(2+) entry function of transient receptor potential canonical (TRPC) 1 and 4 channels in endothelial cells. Molecular Pharmacology. 81: 510-26. PMID 22210847 DOI: 10.1124/Mol.111.074658  0.48
2011 Wang Z, Tiruppathi C, Cho J, Minshall RD, Malik AB. Delivery of nanoparticle: complexed drugs across the vascular endothelial barrier via caveolae. Iubmb Life. 63: 659-67. PMID 21766412 DOI: 10.1002/Iub.485  0.48
2010 Minshall RD, Vandenbroucke EE, Holinstat M, Place AT, Tiruppathi C, Vogel SM, van Nieuw Amerongen GP, Mehta D, Malik AB. Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvascular Research. 80: 240-9. PMID 20417648 DOI: 10.1016/J.Mvr.2010.04.007  0.48
2010 Mirza MK, Yuan J, Gao XP, Garrean S, Brovkovych V, Malik AB, Tiruppathi C, Zhao YY. Caveolin-1 deficiency dampens Toll-like receptor 4 signaling through eNOS activation. The American Journal of Pathology. 176: 2344-51. PMID 20304961 DOI: 10.2353/Ajpath.2010.091088  0.48
2010 Thippegowda PB, Singh V, Sundivakkam PC, Xue J, Malik AB, Tiruppathi C. Ca2+ influx via TRPC channels induces NF-kappaB-dependent A20 expression to prevent thrombin-induced apoptosis in endothelial cells. American Journal of Physiology. Cell Physiology. 298: C656-64. PMID 20032510 DOI: 10.1152/Ajpcell.00456.2009  0.48
2009 Wang Z, Tiruppathi C, Minshall RD, Malik AB. Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. Acs Nano. 3: 4110-6. PMID 19919048 DOI: 10.1021/Nn9012274  0.48
2009 Xue J, Thippegowda PB, Hu G, Bachmaier K, Christman JW, Malik AB, Tiruppathi C. NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene. Physiological Genomics. 38: 42-53. PMID 19351910 DOI: 10.1152/Physiolgenomics.00012.2009  0.48
2009 Sundivakkam PC, Kwiatek AM, Sharma TT, Minshall RD, Malik AB, Tiruppathi C. Caveolin-1 scaffold domain interacts with TRPC1 and IP3R3 to regulate Ca2+ store release-induced Ca2+ entry in endothelial cells. American Journal of Physiology. Cell Physiology. 296: C403-13. PMID 19052258 DOI: 10.1152/Ajpcell.00470.2008  0.48
2009 Bair AM, Thippegowda PB, Freichel M, Cheng N, Ye RD, Vogel SM, Yu Y, Flockerzi V, Malik AB, Tiruppathi C. Ca2+ entry via TRPC channels is necessary for thrombin-induced NF-kappaB activation in endothelial cells through AMP-activated protein kinase and protein kinase Cdelta. The Journal of Biological Chemistry. 284: 563-74. PMID 18990707 DOI: 10.1074/Jbc.M803984200  0.48
2008 Tiruppathi C, Shimizu J, Miyawaki-Shimizu K, Vogel SM, Bair AM, Minshall RD, Predescu D, Malik AB. Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide. The Journal of Biological Chemistry. 283: 4210-8. PMID 18077459 DOI: 10.1074/Jbc.M703153200  0.48
2007 Bachmaier K, Toya S, Gao X, Triantafillou T, Garrean S, Park GY, Frey RS, Vogel S, Minshall R, Christman JW, Tiruppathi C, Malik AB. E3 ubiquitin ligase Cblb regulates the acute inflammatory response underlying lung injury. Nature Medicine. 13: 920-6. PMID 17618294 DOI: 10.1038/Nm1607  0.48
2006 Tiruppathi C, Ahmmed GU, Vogel SM, Malik AB. Ca2+ signaling, TRP channels, and endothelial permeability. Microcirculation (New York, N.Y. : 1994). 13: 693-708. PMID 17085428 DOI: 10.1080/10739680600930347  0.48
2006 Maniatis NA, Brovkovych V, Allen SE, John TA, Shajahan AN, Tiruppathi C, Vogel SM, Skidgel RA, Malik AB, Minshall RD. Novel mechanism of endothelial nitric oxide synthase activation mediated by caveolae internalization in endothelial cells. Circulation Research. 99: 870-7. PMID 16973909 DOI: 10.1161/01.Res.0000245187.08026.47  0.48
2006 Kwiatek AM, Minshall RD, Cool DR, Skidgel RA, Malik AB, Tiruppathi C. Caveolin-1 regulates store-operated Ca2+ influx by binding of its scaffolding domain to transient receptor potential channel-1 in endothelial cells. Molecular Pharmacology. 70: 1174-83. PMID 16822931 DOI: 10.1124/Mol.105.021741  0.48
2006 Paria BC, Bair AM, Xue J, Yu Y, Malik AB, Tiruppathi C. Ca2+ influx induced by protease-activated receptor-1 activates a feed-forward mechanism of TRPC1 expression via nuclear factor-kappaB activation in endothelial cells. The Journal of Biological Chemistry. 281: 20715-27. PMID 16709572 DOI: 10.1074/Jbc.M600722200  0.48
2005 Jho D, Mehta D, Ahmmed G, Gao XP, Tiruppathi C, Broman M, Malik AB. Angiopoietin-1 opposes VEGF-induced increase in endothelial permeability by inhibiting TRPC1-dependent Ca2 influx. Circulation Research. 96: 1282-90. PMID 15920022 DOI: 10.1161/01.Res.0000171894.03801.03  0.48
2004 Paria BC, Vogel SM, Ahmmed GU, Alamgir S, Shroff J, Malik AB, Tiruppathi C. Tumor necrosis factor-alpha-induced TRPC1 expression amplifies store-operated Ca2+ influx and endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L1303-13. PMID 15347566 DOI: 10.1152/Ajplung.00240.2004  0.48
2004 Shajahan AN, Tiruppathi C, Smrcka AV, Malik AB, Minshall RD. Gbetagamma activation of Src induces caveolae-mediated endocytosis in endothelial cells. The Journal of Biological Chemistry. 279: 48055-62. PMID 15345719 DOI: 10.1074/Jbc.M405837200  0.48
2004 Tiruppathi C, Naqvi T, Wu Y, Vogel SM, Minshall RD, Malik AB. Albumin mediates the transcytosis of myeloperoxidase by means of caveolae in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 7699-704. PMID 15136724 DOI: 10.1073/Pnas.0401712101  0.48
2004 Ahmmed GU, Mehta D, Vogel S, Holinstat M, Paria BC, Tiruppathi C, Malik AB. Protein kinase Calpha phosphorylates the TRPC1 channel and regulates store-operated Ca2+ entry in endothelial cells. The Journal of Biological Chemistry. 279: 20941-9. PMID 15016832 DOI: 10.1074/Jbc.M313975200  0.48
2004 Shajahan AN, Timblin BK, Sandoval R, Tiruppathi C, Malik AB, Minshall RD. Role of Src-induced dynamin-2 phosphorylation in caveolae-mediated endocytosis in endothelial cells. The Journal of Biological Chemistry. 279: 20392-400. PMID 15007081 DOI: 10.1074/Jbc.M308710200  0.48
2003 Paria BC, Malik AB, Kwiatek AM, Rahman A, May MJ, Ghosh S, Tiruppathi C. Tumor necrosis factor-alpha induces nuclear factor-kappaB-dependent TRPC1 expression in endothelial cells. The Journal of Biological Chemistry. 278: 37195-203. PMID 12855710 DOI: 10.1074/Jbc.M304287200  0.48
2003 Mehta D, Ahmmed GU, Paria BC, Holinstat M, Voyno-Yasenetskaya T, Tiruppathi C, Minshall RD, Malik AB. RhoA interaction with inositol 1,4,5-trisphosphate receptor and transient receptor potential channel-1 regulates Ca2+ entry. Role in signaling increased endothelial permeability. The Journal of Biological Chemistry. 278: 33492-500. PMID 12766172 DOI: 10.1074/Jbc.M302401200  0.48
2003 John TA, Vogel SM, Tiruppathi C, Malik AB, Minshall RD. Quantitative analysis of albumin uptake and transport in the rat microvessel endothelial monolayer. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L187-96. PMID 12471015 DOI: 10.1152/Ajplung.00152.2002  0.48
2002 Tiruppathi C, Minshall RD, Paria BC, Vogel SM, Malik AB. Role of Ca2+ signaling in the regulation of endothelial permeability. Vascular Pharmacology. 39: 173-85. PMID 12747958 DOI: 10.1016/S1537-1891(03)00007-7  0.48
2002 Tiruppathi C, Freichel M, Vogel SM, Paria BC, Mehta D, Flockerzi V, Malik AB. Impairment of store-operated Ca2+ entry in TRPC4(-/-) mice interferes with increase in lung microvascular permeability. Circulation Research. 91: 70-6. PMID 12114324 DOI: 10.1161/01.Res.0000023391.40106.A8  0.48
2002 Vanhauwe JF, Thomas TO, Minshall RD, Tiruppathi C, Li A, Gilchrist A, Yoon EJ, Malik AB, Hamm HE. Thrombin receptors activate G(o) proteins in endothelial cells to regulate intracellular calcium and cell shape changes. The Journal of Biological Chemistry. 277: 34143-9. PMID 12039967 DOI: 10.1074/Jbc.M204477200  0.48
2002 Minshall RD, Tiruppathi C, Vogel SM, Malik AB. Vesicle formation and trafficking in endothelial cells and regulation of endothelial barrier function. Histochemistry and Cell Biology. 117: 105-12. PMID 11935286 DOI: 10.1007/S00418-001-0367-X  0.48
2002 Mehta D, Tiruppathi C, Sandoval R, Minshall RD, Holinstat M, Malik AB. Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. The Journal of Physiology. 539: 779-89. PMID 11897849 DOI: 10.1113/Jphysiol.2001.013289  0.48
2001 Tiruppathi C, Naqvi T, Sandoval R, Mehta D, Malik AB. Synergistic effects of tumor necrosis factor-alpha and thrombin in increasing endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L958-68. PMID 11557600 DOI: 10.1152/Ajplung.2001.281.4.L958  0.48
2001 John TA, Vogel SM, Minshall RD, Ridge K, Tiruppathi C, Malik AB. Evidence for the role of alveolar epithelial gp60 in active transalveolar albumin transport in the rat lung Journal of Physiology. 533: 547-559. PMID 11389211 DOI: 10.1111/J.1469-7793.2001.0547A.X  0.48
2001 Sandoval R, Malik AB, Minshall RD, Kouklis P, Ellis CA, Tiruppathi C. Ca(2+) signalling and PKCalpha activate increased endothelial permeability by disassembly of VE-cadherin junctions. The Journal of Physiology. 533: 433-45. PMID 11389203 DOI: 10.1111/J.1469-7793.2001.0433A.X  0.48
2001 Vogel SM, Easington CR, Minshall RD, Niles WD, Tiruppathi C, Hollenberg SM, Parrillo JE, Malik AB. Evidence of transcellular permeability pathway in microvessels. Microvascular Research. 61: 87-101. PMID 11162199 DOI: 10.1006/Mvre.2000.2274  0.48
2001 Sandoval R, Malik AB, Naqvi T, Mehta D, Tiruppathi C. Requirement for Ca2+ signaling in the mechanism of thrombin-induced increase in endothelial permeability. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L239-47. PMID 11159002 DOI: 10.1152/Ajplung.2001.280.2.L239  0.48
2000 Minshall RD, Tiruppathi C, Vogel SM, Niles WD, Gilchrist A, Hamm HE, Malik AB. Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway. The Journal of Cell Biology. 150: 1057-70. PMID 10973995 DOI: 10.1083/Jcb.150.5.1057  0.48
2000 Tiruppathi C, Yan W, Sandoval R, Naqvi T, Pronin AN, Benovic JL, Malik AB. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 97: 7440-5. PMID 10861009 DOI: 10.1073/Pnas.97.13.7440  0.48
1999 Ellis CA, Tiruppathi C, Sandoval R, Niles WD, Malik AB. Time course of recovery of endothelial cell surface thrombin receptor (PAR-1) expression. American Journal of Physiology. Cell Physiology. 276: C38-C45. PMID 29590789 DOI: 10.1152/ajpcell.1999.276.1.C38  0.48
1999 Ellis CA, Malik AB, Gilchrist A, Hamm H, Sandoval R, Voyno-Yasenetskaya T, Tiruppathi C. Thrombin induces proteinase-activated receptor-1 gene expression in endothelial cells via activation of Gi-linked Ras/mitogen-activated protein kinase pathway. The Journal of Biological Chemistry. 274: 13718-27. PMID 10224146 DOI: 10.1074/Jbc.274.19.13718  0.48
1999 Ellis CA, Tiruppathi C, Sandoval R, Niles WD, Malik AB. Time course of recovery of endothelial cell surface thrombin receptor (PAR-1) expression. The American Journal of Physiology. 276: C38-45. PMID 9886918 DOI: 10.1152/Ajpcell.1999.276.1.C38  0.48
1998 Yan W, Tiruppathi C, Lum H, Qiao R, Malik AB. Protein kinase Cβ regulates heterologous desensitization of thrombin receptor (PAR-1) in endothelial cells. American Journal of Physiology. Cell Physiology. 274: C387-C395. PMID 29590937 DOI: 10.1152/Ajpcell.1998.274.2.C387  0.48
1997 Nguyen LT, Lum H, Tiruppathì C, Malik AB. Site-specific thrombin receptor antibodies inhibit Casignaling and increased endothelial permeability. American Journal of Physiology. Cell Physiology. 273: C1756-C1763. PMID 29585038 DOI: 10.1152/Ajpcell.1997.273.5.C1756  0.48
1992 Tiruppathi C, Malik AB, Del Vecchio PJ, Keese CR, Giaever I. Electrical method for detection of endothelial cell shape change in real time: assessment of endothelial barrier function. Proceedings of the National Academy of Sciences of the United States of America. 89: 7919-23. PMID 1518814 DOI: 10.1073/Pnas.89.17.7919  0.48
1992 Sugama Y, Tiruppathi C, Janakidevi K, Andersen TT, Fenton JW, Malik AB. Thrombin-induced expression of endothelial P-selectin and intercellular adhesion molecule-1: A mechanism for stabilizing neutrophil adhesion Journal of Cell Biology. 119: 935-944. PMID 1385447 DOI: 10.1083/Jcb.119.4.935  0.48
1992 Tiruppathi C, Lum H, Andersen TT, Fenton JW, Malik AB. Thrombin receptor 14-amino acid peptide binds to endothelial cells and stimulates calcium transients American Journal of Physiology - Lung Cellular and Molecular Physiology. 263. PMID 1332502 DOI: 10.1152/Ajplung.1992.263.5.L595  0.48
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