Mark T. Bedford - Publications

Affiliations: 
The University of Texas Graduate School of Biomedical Sciences at Houston 
Area:
Molecular Biology, Cell Biology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Cheng D, Vemulapalli V, Lu Y, Shen J, Aoyagi S, Fry CJ, Yang Y, Foulds CE, Stossi F, Treviño LS, Mancini MA, O'Malley BW, Walker CL, Boyer TG, Bedford MT. CARM1 methylates MED12 to regulate its RNA-binding ability. Life Science Alliance. 1: e201800117. PMID 30456381 DOI: 10.26508/lsa.201800117  0.32
2017 Bae N, Viviano M, Su X, Lv J, Cheng D, Sagum C, Castellano S, Bai X, Johnson C, Khalil MI, Shen J, Chen K, Li H, Sbardella G, Bedford MT. Developing Spindlin1 small-molecule inhibitors by using protein microarrays. Nature Chemical Biology. PMID 28504676 DOI: 10.1038/nchembio.2377  0.32
2016 Gayatri S, Cowles MW, Vemulapalli V, Cheng D, Sun ZW, Bedford MT. Using oriented peptide array libraries to evaluate methylarginine-specific antibodies and arginine methyltransferase substrate motifs. Scientific Reports. 6: 28718. PMID 27338245 DOI: 10.1038/srep28718  0.32
2016 Metzger E, Willmann D, McMillan J, Forne I, Metzger P, Gerhardt S, Petroll K, von Maessenhausen A, Urban S, Schott AK, Espejo A, Eberlin A, Wohlwend D, Schüle KM, Schleicher M, ... ... Bedford MT, et al. Assembly of methylated KDM1A and CHD1 drives androgen receptor-dependent transcription and translocation. Nature Structural & Molecular Biology. 23: 132-9. PMID 26751641 DOI: 10.1038/nsmb.3153  0.32
2015 Perez CJ, Mecklenburg L, Jaubert J, Martinez-Santamaria L, Iritani BM, Espejo A, Napoli E, Song G, Del Río M, DiGiovanni J, Giulivi C, Bedford MT, Dent SY, Wood RD, Kusewitt DF, et al. Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene. The Journal of Investigative Dermatology. PMID 26288350 DOI: 10.1038/jid.2015.314  0.32
2015 Hadjikyriacou A, Yang Y, Espejo A, Bedford MT, Clarke SG. Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and its Substrate RNA Splicing Factor SF3B2. The Journal of Biological Chemistry. PMID 25979344 DOI: 10.1074/jbc.M115.659433  0.32
2015 Kapoor P, Bao Y, Xiao J, Espejo A, Yang L, Bedford MT, Peng G, Shen X. Phosphorylation-Dependent Enhancement of Rad53 Kinase Activity through the INO80 Chromatin Remodeling Complex. Molecular Cell. 58: 863-9. PMID 25959398 DOI: 10.1016/j.molcel.2015.03.032  0.32
2015 Hu SB, Xiang JF, Li X, Xu Y, Xue W, Huang M, Wong CC, Sagum CA, Bedford MT, Yang L, Cheng D, Chen LL. Protein arginine methyltransferase CARM1 attenuates the paraspeckle-mediated nuclear retention of mRNAs containing IRAlus. Genes & Development. 29: 630-45. PMID 25792598 DOI: 10.1101/gad.257048.114  0.32
2015 Yang Y, Hadjikyriacou A, Xia Z, Gayatri S, Kim D, Zurita-Lopez C, Kelly R, Guo A, Li W, Clarke SG, Bedford MT. PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145. Nature Communications. 6: 6428. PMID 25737013 DOI: 10.1038/ncomms7428  0.32
2014 Estève PO, Terragni J, Deepti K, Chin HG, Dai N, Espejo A, Corrêa IR, Bedford MT, Pradhan S. Methyllysine reader plant homeodomain (PHD) finger protein 20-like 1 (PHF20L1) antagonizes DNA (cytosine-5) methyltransferase 1 (DNMT1) proteasomal degradation. The Journal of Biological Chemistry. 289: 8277-87. PMID 24492612 DOI: 10.1074/jbc.M113.525279  0.32
2013 Dhar S, Vemulapalli V, Patananan AN, Huang GL, Di Lorenzo A, Richard S, Comb MJ, Guo A, Clarke SG, Bedford MT. Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs. Scientific Reports. 3: 1311. PMID 23419748 DOI: 10.1038/srep01311  0.32
2012 Castellano S, Spannhoff A, Milite C, Dal Piaz F, Cheng D, Tosco A, Viviano M, Yamani A, Cianciulli A, Sala M, Cura V, Cavarelli J, Novellino E, Mai A, Bedford MT, et al. Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1. Journal of Medicinal Chemistry. 55: 9875-90. PMID 23095008 DOI: 10.1021/jm301097p  0.32
2012 Cheng D, Vemulapalli V, Bedford MT. Methods applied to the study of protein arginine methylation. Methods in Enzymology. 512: 71-92. PMID 22910203 DOI: 10.1016/B978-0-12-391940-3.00004-4  0.32
2012 Cui G, Park S, Badeaux AI, Kim D, Lee J, Thompson JR, Yan F, Kaneko S, Yuan Z, Botuyan MV, Bedford MT, Cheng JQ, Mer G. PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53. Nature Structural & Molecular Biology. 19: 916-24. PMID 22864287 DOI: 10.1038/nsmb.2353  0.32
2012 Calnan DR, Webb AE, White JL, Stowe TR, Goswami T, Shi X, Espejo A, Bedford MT, Gozani O, Gygi SP, Brunet A. Methylation by Set9 modulates FoxO3 stability and transcriptional activity. Aging. 4: 462-79. PMID 22820736  0.32
2012 Zhao H, Ho PC, Lo YH, Espejo A, Bedford MT, Hung MC, Wang SC. Interaction of proliferation cell nuclear antigen (PCNA) with c-Abl in cell proliferation and response to DNA damages in breast cancer. Plos One. 7: e29416. PMID 22238610 DOI: 10.1371/journal.pone.0029416  0.32
2011 Chang Y, Sun L, Kokura K, Horton JR, Fukuda M, Espejo A, Izumi V, Koomen JM, Bedford MT, Zhang X, Shinkai Y, Fang J, Cheng X. MPP8 mediates the interactions between DNA methyltransferase Dnmt3a and H3K9 methyltransferase GLP/G9a. Nature Communications. 2: 533. PMID 22086334 DOI: 10.1038/ncomms1549  0.32
2011 Cheng D, Valente S, Castellano S, Sbardella G, Di Santo R, Costi R, Bedford MT, Mai A. Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity. Journal of Medicinal Chemistry. 54: 4928-32. PMID 21612300 DOI: 10.1021/jm200453n  0.32
2011 Cheng D, Bedford MT. Xenoestrogens regulate the activity of arginine methyltransferases. Chembiochem : a European Journal of Chemical Biology. 12: 323-9. PMID 21243720 DOI: 10.1002/cbic.201000522  0.32
2011 Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, ... ... Bedford MT, et al. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nature Immunology. 12: 29-36. PMID 21131967 DOI: 10.1038/ni.1968  0.32
2010 Yang Y, Lu Y, Espejo A, Wu J, Xu W, Liang S, Bedford MT. TDRD3 is an effector molecule for arginine-methylated histone marks. Molecular Cell. 40: 1016-23. PMID 21172665 DOI: 10.1016/j.molcel.2010.11.024  0.32
2010 Zhu F, Dollé ME, Berton TR, Kuiper RV, Capps C, Espejo A, McArthur MJ, Bedford MT, van Steeg H, de Vries A, Johnson DG. Mouse models for the p53 R72P polymorphism mimic human phenotypes. Cancer Research. 70: 5851-9. PMID 20587514 DOI: 10.1158/0008-5472.CAN-09-4646  0.32
2010 O'Brien KB, Alberich-Jordà M, Yadav N, Kocher O, Diruscio A, Ebralidze A, Levantini E, Sng NJ, Bhasin M, Caron T, Kim D, Steidl U, Huang G, Halmos B, Rodig SJ, ... Bedford MT, et al. CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells. Development (Cambridge, England). 137: 2147-56. PMID 20530543 DOI: 10.1242/dev.037150  0.32
2010 Castellano S, Milite C, Ragno R, Simeoni S, Mai A, Limongelli V, Novellino E, Bauer I, Brosch G, Spannhoff A, Cheng D, Bedford MT, Sbardella G. Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1). Chemmedchem. 5: 398-414. PMID 20091730 DOI: 10.1002/cmdc.200900459  0.32
2010 Quinn AM, Bedford MT, Espejo A, Spannhoff A, Austin CP, Oppermann U, Simeonov A. A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics. Nucleic Acids Research. 38: e11. PMID 19897549 DOI: 10.1093/nar/gkp899  0.32
2010 Kim D, Lee J, Cheng D, Li J, Carter C, Richie E, Bedford MT. Enzymatic activity is required for the in vivo functions of CARM1. The Journal of Biological Chemistry. 285: 1147-52. PMID 19897492 DOI: 10.1074/jbc.M109.035865  0.32
2009 Bua DJ, Kuo AJ, Cheung P, Liu CL, Migliori V, Espejo A, Casadio F, Bassi C, Amati B, Bedford MT, Guccione E, Gozani O. Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks. Plos One. 4: e6789. PMID 19956676 DOI: 10.1371/journal.pone.0006789  0.32
2009 Lu M, Yang J, Ren Z, Sabui S, Espejo A, Bedford MT, Jacobson RH, Jeruzalmi D, McMurray JS, Chen X. Crystal structure of the three tandem FF domains of the transcription elongation regulator CA150. Journal of Molecular Biology. 393: 397-408. PMID 19660470 DOI: 10.1016/j.jmb.2009.07.086  0.32
2008 Schotta G, Sengupta R, Kubicek S, Malin S, Kauer M, Callén E, Celeste A, Pagani M, Opravil S, De La Rosa-Velazquez IA, Espejo A, Bedford MT, Nussenzweig A, Busslinger M, Jenuwein T. A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse. Genes & Development. 22: 2048-61. PMID 18676810 DOI: 10.1101/gad.476008  0.32
2008 Mai A, Cheng D, Bedford MT, Valente S, Nebbioso A, Perrone A, Brosch G, Sbardella G, De Bellis F, Miceli M, Altucci L. epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors. Journal of Medicinal Chemistry. 51: 2279-90. PMID 18348515 DOI: 10.1021/jm701595q  0.32
2008 Yadav N, Cheng D, Richard S, Morel M, Iyer VR, Aldaz CM, Bedford MT. CARM1 promotes adipocyte differentiation by coactivating PPARgamma. Embo Reports. 9: 193-8. PMID 18188184 DOI: 10.1038/sj.embor.7401151  0.32
2008 Iberg AN, Espejo A, Cheng D, Kim D, Michaud-Levesque J, Richard S, Bedford MT. Arginine methylation of the histone H3 tail impedes effector binding. The Journal of Biological Chemistry. 283: 3006-10. PMID 18077460 DOI: 10.1074/jbc.C700192200  0.32
2007 Sayegh J, Webb K, Cheng D, Bedford MT, Clarke SG. Regulation of protein arginine methyltransferase 8 (PRMT8) activity by its N-terminal domain. The Journal of Biological Chemistry. 282: 36444-53. PMID 17925405 DOI: 10.1074/jbc.M704650200  0.32
2007 Mai A, Valente S, Cheng D, Perrone A, Ragno R, Simeoni S, Sbardella G, Brosch G, Nebbioso A, Conte M, Altucci L, Bedford MT. Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors. Chemmedchem. 2: 987-91. PMID 17458842 DOI: 10.1002/cmdc.200700023  0.32
2007 Swiercz R, Cheng D, Kim D, Bedford MT. Ribosomal protein rpS2 is hypomethylated in PRMT3-deficient mice. The Journal of Biological Chemistry. 282: 16917-23. PMID 17439947 DOI: 10.1074/jbc.M609778200  0.32
2007 Cheng D, Côté J, Shaaban S, Bedford MT. The arginine methyltransferase CARM1 regulates the coupling of transcription and mRNA processing. Molecular Cell. 25: 71-83. PMID 17218272 DOI: 10.1016/j.molcel.2006.11.019  0.32
2006 El Messaoudi S, Fabbrizio E, Rodriguez C, Chuchana P, Fauquier L, Cheng D, Theillet C, Vandel L, Bedford MT, Sardet C. Coactivator-associated arginine methyltransferase 1 (CARM1) is a positive regulator of the Cyclin E1 gene. Proceedings of the National Academy of Sciences of the United States of America. 103: 13351-6. PMID 16938873 DOI: 10.1073/pnas.0605692103  0.32
2006 Kim J, Daniel J, Espejo A, Lake A, Krishna M, Xia L, Zhang Y, Bedford MT. Tudor, MBT and chromo domains gauge the degree of lysine methylation. Embo Reports. 7: 397-403. PMID 16415788 DOI: 10.1038/sj.embor.7400625  0.32
2005 Bedford MT, Richard S. Arginine methylation: An emerging regulator of protein function Molecular Cell. 18: 263-272. PMID 15866169 DOI: 10.1016/j.molcel.2005.04.003  0.32
2005 Boulanger MC, Liang C, Russell RS, Lin R, Bedford MT, Wainberg MA, Richard S. Methylation of Tat by PRMT6 regulates human immunodeficiency virus type 1 gene expression. Journal of Virology. 79: 124-31. PMID 15596808 DOI: 10.1128/JVI.79.1.124-131.2005  0.32
2004 Lee J, Cheng D, Bedford MT. Techniques in protein methylation. Methods in Molecular Biology (Clifton, N.J.). 284: 195-208. PMID 15173617 DOI: 10.1385/1-59259-816-1:195  0.32
2004 Kim J, Lee J, Yadav N, Wu Q, Carter C, Richard S, Richie E, Bedford MT. Loss of CARM1 results in hypomethylation of thymocyte cyclic AMP-regulated phosphoprotein and deregulated early T cell development. The Journal of Biological Chemistry. 279: 25339-44. PMID 15096520 DOI: 10.1074/jbc.M402544200  0.32
2004 Cheng D, Yadav N, King RW, Swanson MS, Weinstein EJ, Bedford MT. Small molecule regulators of protein arginine methyltransferases. The Journal of Biological Chemistry. 279: 23892-9. PMID 15056663 DOI: 10.1074/jbc.M401853200  0.32
2004 Espejo A, Bedford MT. Protein-domain microarrays. Methods in Molecular Biology (Clifton, N.J.). 264: 173-81. PMID 15020789 DOI: 10.1385/1-59259-759-9:173  0.32
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