Lori Sussel - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Cell Biology

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L. Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human β cell specification. Development (Cambridge, England). PMID 32467243 DOI: 10.1242/dev.189977  0.48
2016 Xuan S, Sussel L. GATA4 and GATA6 regulate pancreatic endoderm identity through inhibition of hedgehog signaling. Development (Cambridge, England). 143: 780-6. PMID 26932670 DOI: 10.1242/dev.127217  0.48
2015 Gross S, Balderes D, Liu J, Asfaha S, Gu G, Wang TC, Sussel L. Nkx2.2 is expressed in a subset of enteroendocrine cells with expanded lineage potential. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00244.2015. PMID 26492922 DOI: 10.1152/ajpgi.00244.2015  0.48
2015 Roybon L, Mastracci TL, Li J, Stott SR, Leiter AB, Sussel L, Brundin P, Li JY. The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1. Plos One. 10: e0128035. PMID 26030886 DOI: 10.1371/journal.pone.0128035  0.48
2015 Singer RA, Arnes L, Sussel L. Noncoding RNAs in β cell biology. Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 77-85. PMID 25692923 DOI: 10.1097/MED.0000000000000141  0.48
2014 Sussel L, Niswander L. Editorial overview: developmental mechanisms, patterning and evolution. Current Opinion in Genetics & Development. 27: v-vii. PMID 24998023 DOI: 10.1016/j.gde.2014.06.007  0.48
2014 Clark JK, O'keefe A, Mastracci TL, Sussel L, Matise MP, Kucenas S. Mammalian Nkx2.2+ perineurial glia are essential for motor nerve development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 1116-29. PMID 24979729 DOI: 10.1002/dvdy.24158  0.48
2014 Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. Diabetes Care. 37: 1751-8. PMID 24812433 DOI: 10.2337/dc14-0396  0.48
2014 Halban PA, Polonsky KS, Bowden DW, Hawkins MA, Ling C, Mather KJ, Powers AC, Rhodes CJ, Sussel L, Weir GC. β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. The Journal of Clinical Endocrinology and Metabolism. 99: 1983-92. PMID 24712577 DOI: 10.1210/jc.2014-1425  0.48
2014 Nair KS, Abel ED, Adler SG, Dyck PJ, Gardner TW, Haskins KM, Hotamisligil G, Jensen MD, Krook A, Mandarino LJ, Mitchell BD, Pessin JE, Sowers JR, Sussel L, Wareham N, et al. Time to look back and to look forward. Diabetes. 63: 1169-70. PMID 24651796 DOI: 10.2337/db14-0067  0.48
2013 Suissa Y, Magenheim J, Stolovich-Rain M, Hija A, Collombat P, Mansouri A, Sussel L, Sosa-Pineda B, McCracken K, Wells JM, Heller RS, Dor Y, Glaser B. Gastrin: a distinct fate of neurogenin3 positive progenitor cells in the embryonic pancreas. Plos One. 8: e70397. PMID 23940571 DOI: 10.1371/journal.pone.0070397  0.48
2013 Lugani F, Arora R, Papeta N, Patel A, Zheng Z, Sterken R, Singer RA, Caridi G, Mendelsohn C, Sussel L, Papaioannou VE, Gharavi AG. A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse. Plos Genetics. 9: e1003206. PMID 23437001 DOI: 10.1371/journal.pgen.1003206  0.48
2013 Mastracci TL, Anderson KR, Papizan JB, Sussel L. Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas. Plos Genetics. 9: e1003278. PMID 23408910 DOI: 10.1371/journal.pgen.1003278  0.48
2013 Ioannou M, Serafimidis I, Arnes L, Sussel L, Singh S, Vasiliou V, Gavalas A. ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Developmental Biology. 374: 153-63. PMID 23142317 DOI: 10.1016/j.ydbio.2012.10.030  0.48
2012 Arnes L, Hill JT, Gross S, Magnuson MA, Sussel L. Ghrelin expression in the mouse pancreas defines a unique multipotent progenitor population. Plos One. 7: e52026. PMID 23251675 DOI: 10.1371/journal.pone.0052026  0.48
2012 Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, ... ... Sussel L, et al. Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metabolism. 16: 435-48. PMID 23040067 DOI: 10.1016/j.cmet.2012.08.010  0.48
2012 Xuan S, Borok MJ, Decker KJ, Battle MA, Duncan SA, Hale MA, Macdonald RJ, Sussel L. Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis. The Journal of Clinical Investigation. 122: 3516-28. PMID 23006325 DOI: 10.1172/JCI63352  0.48
2012 Talchai C, Xuan S, Lin HV, Sussel L, Accili D. Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure. Cell. 150: 1223-34. PMID 22980982 DOI: 10.1016/j.cell.2012.07.029  0.48
2011 Papizan JB, Singer RA, Tschen SI, Dhawan S, Friel JM, Hipkens SB, Magnuson MA, Bhushan A, Sussel L. Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming. Genes & Development. 25: 2291-305. PMID 22056672 DOI: 10.1101/gad.173039.111  0.48
2011 Mastracci TL, Wilcox CL, Arnes L, Panea C, Golden JA, May CL, Sussel L. Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Developmental Biology. 359: 1-11. PMID 21856296 DOI: 10.1016/j.ydbio.2011.08.001  0.48
2011 Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L. The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development (Cambridge, England). 138: 3213-24. PMID 21750032 DOI: 10.1242/dev.058693  0.48
2011 Hill JT, Anderson KR, Mastracci TL, Kaestner KH, Sussel L. Novel computational analysis of protein binding array data identifies direct targets of Nkx2.2 in the pancreas. Bmc Bioinformatics. 12: 62. PMID 21352540 DOI: 10.1186/1471-2105-12-62  0.48
2011 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ. Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development (Cambridge, England). 138: 531-41. PMID 21205797 DOI: 10.1242/dev.058917  0.48
2010 Lek M, Dias JM, Marklund U, Uhde CW, Kurdija S, Lei Q, Sussel L, Rubenstein JL, Matise MP, Arnold HH, Jessell TM, Ericson J. A homeodomain feedback circuit underlies step-function interpretation of a Shh morphogen gradient during ventral neural patterning. Development (Cambridge, England). 137: 4051-60. PMID 21062862 DOI: 10.1242/dev.054288  0.48
2010 Raum JC, Hunter CS, Artner I, Henderson E, Guo M, Elghazi L, Sosa-Pineda B, Ogihara T, Mirmira RG, Sussel L, Stein R. Islet β-cell-specific MafA transcription requires the 5′-Flanking conserved region 3 control domain Molecular and Cellular Biology. 30: 4234-4244. PMID 20584984 DOI: 10.1128/MCB.01396-09  0.48
2010 Gu C, Stein GH, Pan N, Goebbels S, Hörnberg H, Nave KA, Herrera P, White P, Kaestner KH, Sussel L, Lee JE. Pancreatic beta cells require NeuroD to achieve and maintain functional maturity. Cell Metabolism. 11: 298-310. PMID 20374962 DOI: 10.1016/j.cmet.2010.03.006  0.48
2010 Hill JT, Chao CS, Anderson KR, Kaufman F, Johnson CW, Sussel L. Nkx2.2 activates the ghrelin promoter in pancreatic islet cells. Molecular Endocrinology (Baltimore, Md.). 24: 381-90. PMID 19965928 DOI: 10.1210/me.2009-0360  0.48
2010 Roybon L, Mastracci TL, Ribeiro D, Sussel L, Brundin P, Li JY. GABAergic differentiation induced by Mash1 is compromised by the bHLH proteins Neurogenin2, NeuroD1, and NeuroD2. Cerebral Cortex (New York, N.Y. : 1991). 20: 1234-44. PMID 19767311 DOI: 10.1093/cercor/bhp187  0.48
2009 Anderson KR, White P, Kaestner KH, Sussel L. Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development. Bmc Developmental Biology. 9: 65. PMID 20003319 DOI: 10.1186/1471-213X-9-65  0.48
2009 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L. Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. The Journal of Biological Chemistry. 284: 31236-48. PMID 19759004 DOI: 10.1074/jbc.M109.048694  0.48
2009 Prakash N, Puelles E, Freude K, Trümbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W. Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. Development (Cambridge, England). 136: 2545-55. PMID 19592574 DOI: 10.1242/dev.031781  0.48
2009 Hill JT, Mastracci TL, Vinton C, Doyle ML, Anderson KR, Loomis ZL, Schrunk JM, Minic AD, Prabakar KR, Pugliese A, Sun Y, Smith RG, Sussel L. Ghrelin is dispensable for embryonic pancreatic islet development and differentiation. Regulatory Peptides. 157: 51-6. PMID 19268691 DOI: 10.1016/j.regpep.2009.02.013  0.48
2009 Jedlicka P, Sui X, Sussel L, Gutierrez-Hartmann A. Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. The American Journal of Pathology. 174: 1280-90. PMID 19264912 DOI: 10.2353/ajpath.2009.080409  0.48
2008 Desai S, Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, Minic A, McCoy E, Sussel L. Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine. Developmental Biology. 313: 58-66. PMID 18022152 DOI: 10.1016/j.ydbio.2007.09.047  0.84
2007 Chao CS, Loomis ZL, Lee JE, Sussel L. Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Developmental Biology. 312: 523-32. PMID 17988662 DOI: 10.1016/j.ydbio.2007.09.057  0.6
2007 Doyle MJ, Sussel L. Nkx2.2 regulates beta-cell function in the mature islet. Diabetes. 56: 1999-2007. PMID 17456846 DOI: 10.2337/db06-1766  0.84
2007 Doyle MJ, Loomis ZL, Sussel L. Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development (Cambridge, England). 134: 515-23. PMID 17202186 DOI: 10.1242/dev.02763  0.84
2006 Prakash N, Brodski C, Naserke T, Puelles E, Gogoi R, Hall A, Panhuysen M, Echevarria D, Sussel L, Weisenhorn DM, Martinez S, Arenas E, Simeone A, Wurst W. A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (Cambridge, England). 133: 89-98. PMID 16339193 DOI: 10.1242/dev.02181  0.48
2004 Doyle MJ, Sussel L. Engineering islets: lessons from stem cells and embryonic development. Endocrinology and Metabolism Clinics of North America. 33: 149-62, x. PMID 15053900 DOI: 10.1016/S0889-8529(03)00100-2  0.84
2004 Wang J, Elghazi L, Parker SE, Kizilocak H, Asano M, Sussel L, Sosa-Pineda B. The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic β-cell differentiation Developmental Biology. 266: 178-189. PMID 14729487 DOI: 10.1016/j.ydbio.2003.10.018  0.48
1999 Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J. Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling. Nature. 398: 622-7. PMID 10217145 DOI: 10.1038/19315  0.48
1998 Furuta H, Horikawa Y, Iwasaki N, Hara M, Sussel L, Le Beau MM, Davis EM, Ogata M, Iwamoto Y, German MS, Bell GI. β-cell transcription factors and diabetes: Mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese Diabetes. 47: 1356-1358. PMID 9703340 DOI: 10.2337/diabetes.47.8.1356  0.48
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