Jeffrey Singer - Publications

Affiliations: 
Brown University, Providence, RI 
Area:
Molecular Biology, Cell Biology

12/44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Davidge B, de Oliveira Rebola KG, Agbor LN, Sigmund CD, Singer JD. Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E. Journal of Cell Science. PMID 31636116 DOI: 10.1242/Jcs.233049  0.362
2018 Cornelius RJ, Zhang C, Erspamer KJ, Agbor LN, Sigmund CD, Singer JD, Yang CL, Ellison DH. Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension. American Journal of Physiology. Renal Physiology. PMID 29897280 DOI: 10.1152/Ajprenal.00602.2017  0.347
2014 Wimuttisuk W, West M, Davidge B, Yu K, Salomon A, Singer JD. Novel Cul3 binding proteins function to remodel E3 ligase complexes. Bmc Cell Biology. 15: 28. PMID 25011449 DOI: 10.1186/1471-2121-15-28  0.608
2012 Mathew R, Seiler MP, Scanlon ST, Mao AP, Constantinides MG, Bertozzi-Villa C, Singer JD, Bendelac A. BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Nature. 491: 618-21. PMID 23086144 DOI: 10.1038/Nature11548  0.343
2011 Marshall J, Blair LA, Singer JD. BTB-Kelch proteins and ubiquitination of kainate receptors. Advances in Experimental Medicine and Biology. 717: 115-25. PMID 21713671 DOI: 10.1007/978-1-4419-9557-5_10  0.351
2009 Cummings CM, Bentley CA, Perdue SA, Baas PW, Singer JD. The Cul3/Klhdc5 E3 ligase regulates p60/katanin and is required for normal mitosis in mammalian cells. The Journal of Biological Chemistry. 284: 11663-75. PMID 19261606 DOI: 10.1074/Jbc.M809374200  0.399
2009 Plafker KS, Singer JD, Plafker SM. The ubiquitin conjugating enzyme, UbcM2, engages in novel interactions with components of cullin-3 based E3 ligases. Biochemistry. 48: 3527-37. PMID 19256485 DOI: 10.1021/bi801971m  0.459
2007 Watai Y, Kobayashi A, Nagase H, Mizukami M, McEvoy J, Singer JD, Itoh K, Yamamoto M. Subcellular localization and cytoplasmic complex status of endogenous Keap1. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 12: 1163-78. PMID 17903176 DOI: 10.1111/J.1365-2443.2007.01118.X  0.635
2007 McEvoy JD, Kossatz U, Malek N, Singer JD. Constitutive turnover of cyclin E by Cul3 maintains quiescence. Molecular and Cellular Biology. 27: 3651-66. PMID 17339333 DOI: 10.1128/Mcb.00720-06  0.626
2007 Wimuttisuk W, Singer JD. The Cullin3 ubiquitin ligase functions as a Nedd8-bound heterodimer. Molecular Biology of the Cell. 18: 899-909. PMID 17192413 DOI: 10.1091/Mbc.E06-06-0542  0.618
2006 Salinas GD, Blair LA, Needleman LA, Gonzales JD, Chen Y, Li M, Singer JD, Marshall J. Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 281: 40164-73. PMID 17062563 DOI: 10.1074/Jbc.M608194200  0.344
2003 Welcker M, Singer J, Loeb KR, Grim J, Bloecher A, Gurien-West M, Clurman BE, Roberts JM. Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation. Molecular Cell. 12: 381-92. PMID 14536078 DOI: 10.1016/S1097-2765(03)00287-9  0.451
Low-probability matches (unlikely to be authored by this person)
2014 McCormick JA, Yang CL, Zhang C, Davidge B, Blankenstein KI, Terker AS, Yarbrough B, Meermeier NP, Park HJ, McCully B, West M, Borschewski A, Himmerkus N, Bleich M, Bachmann S, ... ... Singer JD, et al. Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3. The Journal of Clinical Investigation. 124: 4723-36. PMID 25250572 DOI: 10.1172/Jci76126  0.276
2015 Zhang C, Meermeier NP, Terker AS, Blankenstein KI, Singer JD, Hadchouel J, Ellison DH, Yang CL. Degradation by Cullin3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension. Biochemical and Biophysical Research Communications. PMID 26607111 DOI: 10.1016/J.Bbrc.2015.11.067  0.268
2012 Werwein E, Schmedt T, Hoffmann H, Usadel C, Obermann N, Singer JD, Klempnauer KH. B-Myb promotes S-phase independently of its sequence-specific DNA binding activity and interacts with polymerase delta-interacting protein 1 (Pdip1). Cell Cycle (Georgetown, Tex.). 11: 4047-58. PMID 23032261 DOI: 10.4161/cc.22386  0.257
2014 Mathew R, Mao AP, Chiang AH, Bertozzi-Villa C, Bunker JJ, Scanlon ST, McDonald BD, Constantinides MG, Hollister K, Singer JD, Dent AL, Dinner AR, Bendelac A. A negative feedback loop mediated by the Bcl6-cullin 3 complex limits Tfh cell differentiation. The Journal of Experimental Medicine. 211: 1137-51. PMID 24863065 DOI: 10.1084/Jem.20132267  0.242
2023 Xia QQ, Walker AK, Song C, Wang J, Singh A, Mobley JA, Xuan ZX, Singer JD, Powell CM. Effects of heterozygous deletion of autism-related gene Cullin-3 in mice. Plos One. 18: e0283299. PMID 37428799 DOI: 10.1371/journal.pone.0283299  0.241
2010 Claiborn KC, Sachdeva MM, Cannon CE, Groff DN, Singer JD, Stoffers DA. Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice. The Journal of Clinical Investigation. 120: 3713-21. PMID 20811152 DOI: 10.1172/Jci40440  0.241
2000 Sheaff RJ, Singer JD, Swanger J, Smitherman M, Roberts JM, Clurman BE. Proteasomal turnover of p21(Cip1) does not require p21(Cip1) ubiquitination Molecular Cell. 5: 403-410. PMID 10882081 DOI: 10.1016/S1097-2765(00)80435-9  0.24
2010 Kossatz U, Breuhahn K, Wolf B, Hardtke-Wolenski M, Wilkens L, Steinemann D, Singer S, Brass F, Kubicka S, Schlegelberger B, Schirmacher P, Manns MP, Singer JD, Malek NP. The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells. The Journal of Clinical Investigation. 120: 3820-33. PMID 20978349 DOI: 10.1172/JCI41959  0.24
2017 Li X, Zhang Z, Li L, Gong W, Lazenby AJ, Swanson BJ, Herring LE, Asara JM, Singer JD, Wen H. Myeloid-derived cullin 3 promotes STAT3 phosphorylation by inhibiting OGT expression and protects against intestinal inflammation. The Journal of Experimental Medicine. PMID 28280036 DOI: 10.1084/Jem.20161105  0.219
2017 Ferdaus MZ, Miller LN, Agbor LN, Saritas T, Singer JD, Sigmund CD, McCormick JA. Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects. Jci Insight. 2. PMID 29263298 DOI: 10.1172/Jci.Insight.96700  0.207
2023 Yarosz EL, Kumar A, Singer JD, Chang CH. Cullin 3-Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation. Immunohorizons. 7: 235-242. PMID 36951874 DOI: 10.4049/immunohorizons.2300002  0.206
2019 Saritas T, Cuevas CA, Ferdaus MZ, Kuppe C, Kramann R, Moeller MJ, Floege J, Singer JD, McCormick JA. Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis. Scientific Reports. 9: 4596. PMID 30872636 DOI: 10.1038/s41598-019-40795-0  0.181
2019 Blondelle J, Tallapaka K, Seto JT, Ghassemian M, Clark M, Laitila JM, Bournazos A, Singer JD, Lange S. Cullin-3 dependent deregulation of ACTN1 represents a new pathogenic mechanism in nemaline myopathy. Jci Insight. 5. PMID 30990797 DOI: 10.1172/jci.insight.125665  0.167
2005 Klysik J, Singer JD. Mice with the enhanced green fluorescent protein gene knocked in to chromosome 11 exhibit normal transmission ratios. Biochemical Genetics. 43: 321-33. PMID 16144308  0.155
2016 Israeli E, Dryanovski DI, Schumacker PT, Chandel NS, Singer JD, Julien JP, Goldman RD, Opal P. Intermediate filament aggregates cause mitochondrial dysmotility and increase energy demands in Giant Axonal Neuropathy. Human Molecular Genetics. PMID 27000625 DOI: 10.1093/Hmg/Ddw081  0.144
2021 Cummings CM, Singer JD. Cul3 is required for normal development of the mammary gland. Cell and Tissue Research. PMID 33825963 DOI: 10.1007/s00441-021-03456-1  0.142
2015 Gladwyn-Ng IE, Li SS, Qu Z, Davis JM, Ngo L, Haas M, Singer J, Heng JI. Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex. Neural Development. 10: 9. PMID 25888806 DOI: 10.1186/S13064-015-0032-Z  0.12
2014 Lampert L, Timonen B, Smith S, Davidge B, Li H, Conley JF, Singer JD, Jiao J. Amorphous alumina nanowire array efficiently delivers Ac-DEVD-CHO to inhibit apoptosis of dendritic cells. Chemical Communications (Cambridge, England). 50: 1234-7. PMID 24336780 DOI: 10.1039/C3Cc48088G  0.1
2015 Owen LJ, Strongin RM, Singer JD, Abramson JJ. Elevated Homocysteine Levels Result in Carbonyl Formation on RyR2 and Enhanced Sensitivity of Sarcoplasmic Reticulum to Activation by Calcium Biophysical Journal. 108: 263a. DOI: 10.1016/J.Bpj.2014.11.1451  0.097
2018 DiToro D, Winstead CJ, Pham D, Witte S, Andargachew R, Singer JR, Wilson CG, Zindl CL, Luther RJ, Silberger DJ, Weaver BT, Kolawole EM, Martinez RJ, Turner H, Hatton RD, et al. Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science (New York, N.Y.). 361. PMID 30213884 DOI: 10.1126/Science.Aao2933  0.09
2022 Zindl CL, Witte SJ, Laufer VA, Gao M, Yue Z, Janowski KM, Cai B, Frey BF, Silberger DJ, Harbour SN, Singer JR, Turner H, Lund FE, Vallance BA, Rosenberg AF, et al. A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts. Immunity. 55: 494-511.e11. PMID 35263568 DOI: 10.1016/j.immuni.2022.02.003  0.087
2006 Kossatz U, Singer J, Manns M, Malek N. 115 The cullin 3 dependent ubiquitylation system regulates the genetic stability of hepatocytes Journal of Hepatology. 44: S51. DOI: 10.1016/S0168-8278(06)80116-9  0.082
2008 Kossatz U, Singer J, Manns M, Malek N. 336 CUL3 IS REQUIRED FOR STEM CELL DIFFERENTIATION AND PREVENTS THE GENERATION OF HEPATIC TUMOR STEM CELLS Journal of Hepatology. 48: S132. DOI: 10.1016/S0168-8278(08)60338-4  0.08
2012 Ye Y, Yaeger D, Owen LJ, Escobedo JO, Wang J, Singer JD, Strongin RM, Abramson JJ. Designing calcium release channel inhibitors with enhanced electron donor properties: stabilizing the closed state of ryanodine receptor type 1. Molecular Pharmacology. 81: 53-62. PMID 21989257 DOI: 10.1124/Mol.111.074740  0.073
2019 Agbor LN, Nair AR, Wu J, Lu KT, Davis DR, Keen HL, Quelle FW, McCormick JA, Singer JD, Sigmund CD. Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension. Jci Insight. 5. PMID 31184598 DOI: 10.1172/Jci.Insight.129793  0.064
2019 Singer JR, Blosser EG, Zindl CL, Silberger DJ, Conlan S, Laufer VA, DiToro D, Deming C, Kumar R, Morrow CD, Segre JA, Gray MJ, Randolph DA, Weaver CT. Preventing dysbiosis of the neonatal mouse intestinal microbiome protects against late-onset sepsis. Nature Medicine. PMID 31700190 DOI: 10.1038/S41591-019-0640-Y  0.062
2015 Singer JR, Weaver CT. Daughter's Tolerance of Mom Matters in Mate Choice. Cell. 162: 467-9. PMID 26232215 DOI: 10.1016/J.Cell.2015.07.030  0.041
2011 Rodriguez FN, Low RA, Singer JA, Bornstein AM, Bradford Doxey J, Hashimoto LA, Rassadi R, Dolce CJ, Hollingworth A, Hayes C, Shively CJ. A new technique for robotic thyroidectomy: "the daVinci gasless single-incision axillary approach". Journal of Robotic Surgery. 5: 157-62. PMID 27637701 DOI: 10.1007/s11701-010-0220-0  0.029
2019 Singer JA, Sullum JZ, Schatman ME. Today's nonmedical opioid users are not yesterday's patients; implications of data indicating stable rates of nonmedical use and pain reliever use disorder. Journal of Pain Research. 12: 617-620. PMID 30799947 DOI: 10.2147/JPR.S199750  0.01
2013 Singer JA. Toward medical dystopia. The Journal of Trauma and Acute Care Surgery. 75: 517-9. PMID 24089122 DOI: 10.1097/TA.0b013e3182a040f6  0.01
2009 Kossatz U, Singer J, Schirmacher P, Breuhahn K, Manns M, Malek N. Der Verlust von Cullin 3 führt zur Bildung prä-maligner Tumorstammzellen Zeitschrift FüR Gastroenterologie. 47. DOI: 10.1055/s-0029-1191879  0.01
2003 Singer JA, Korn R. Reversed rotation of the midgut presenting as duodenal and transverse colon obstruction in a 19-year-old man. Journal of the American College of Surgeons. 197: 1048-9. PMID 14644295 DOI: 10.1016/j.jamcollsurg.2003.06.007  0.01
Hide low-probability matches.