Raul M. Torres - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Immunology, Molecular Biology, Cell Biology

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Year Citation  Score
2023 Castleman MJ, Santos AL, Lesteberg KE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection. Frontiers in Immunology. 14: 1213344. PMID 37638016 DOI: 10.3389/fimmu.2023.1213344  0.335
2023 Turner JA, Fredrickson MA, D'Antonio M, Katsnelson E, MacBeth M, Van Gulick R, Chimed TS, McCarter M, D'Alessandro A, Robinson WA, Couts KL, Pelanda R, Klarquist J, Tobin RP, Torres RM. Lysophosphatidic acid modulates CD8 T cell immunosurveillance and metabolism to impair anti-tumor immunity. Nature Communications. 14: 3214. PMID 37270644 DOI: 10.1038/s41467-023-38933-4  0.32
2023 Torres RM, Turner JA, D'Antonio M, Pelanda R, Kremer KN. Regulation of CD8 T-cell signaling, metabolism, and cytotoxic activity by extracellular lysophosphatidic acid. Immunological Reviews. PMID 37096808 DOI: 10.1111/imr.13208  0.386
2023 McCaleb MR, Miranda AM, Ratliff KC, Torres RM, Pelanda R. CD19 Is Internalized Together with IgM in Proportion to B Cell Receptor Stimulation and Is Modulated by Phosphatidylinositol 3-Kinase in Bone Marrow Immature B Cells. Immunohorizons. 7: 49-63. PMID 36637517 DOI: 10.4049/immunohorizons.2200092  0.328
2022 Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. SARS-CoV-2 infection relaxes peripheral B cell tolerance. The Journal of Experimental Medicine. 219. PMID 35420627 DOI: 10.1084/jem.20212553  0.38
2022 Kremer KN, Buser A, Thumkeo D, Narumiya S, Jacobelli J, Pelanda R, Torres RM. LPA suppresses T cell function by altering the cytoskeleton and disrupting immune synapse formation. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118816119. PMID 35394866 DOI: 10.1073/pnas.2118816119  0.358
2022 Peterson JN, Boackle SA, Taitano SH, Sang A, Lang J, Kelly M, Rahkola JT, Miranda AM, Sheridan RM, Thurman JM, Rao VK, Torres RM, Pelanda R. Elevated Detection of Dual Antibody B Cells Identifies Lupus Patients With B Cell-Reactive VH4-34 Autoantibodies. Frontiers in Immunology. 13: 795209. PMID 35185888 DOI: 10.3389/fimmu.2022.795209  0.458
2022 Pelanda R, Greaves SA, Alves da Costa T, Cedrone LM, Campbell ML, Torres RM. B-cell intrinsic and extrinsic signals that regulate central tolerance of mouse and human B cells. Immunological Reviews. PMID 34997597 DOI: 10.1111/imr.13062  0.42
2021 Fujiwara Y, Torphy RJ, Sun Y, Miller EN, Ho F, Borcherding N, Wu T, Torres RM, Zhang W, Schulick RD, Zhu Y. The GPR171 pathway suppresses T cell activation and limits antitumor immunity. Nature Communications. 12: 5857. PMID 34615877 DOI: 10.1038/s41467-021-26135-9  0.374
2021 Alves da Costa T, Peterson JN, Lang J, Shulman J, Liang X, Freed BM, Boackle SA, Lauzurica P, Torres RM, Pelanda R. Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33850015 DOI: 10.1073/pnas.2021570118  0.397
2020 Mathew D, Torres RM. Lysophosphatidic Acid Is an Inflammatory Lipid Exploited by Cancers for Immune Evasion Mechanisms Similar and Distinct From CTLA-4 and PD-1. Frontiers in Immunology. 11: 531910. PMID 33584637 DOI: 10.3389/fimmu.2020.531910  0.363
2020 Agazio A, Cimons J, Shotts KM, Guo K, Santiago ML, Pelanda R, Torres RM. Histone H2A-Reactive B Cells Are Functionally Anergic in Healthy Mice With Potential to Provide Humoral Protection Against HIV-1. Frontiers in Immunology. 11: 1565. PMID 32849530 DOI: 10.3389/Fimmu.2020.01565  0.53
2020 Lee SC, Dacheux MA, Norman DD, Balázs L, Torres RM, Augelli-Szafran CE, Tigyi GJ. Regulation of Tumor Immunity by Lysophosphatidic Acid. Cancers. 12. PMID 32397679 DOI: 10.3390/Cancers12051202  0.363
2019 Agazio A, Torres RM. Ushering along B cells to neutralize HIV. Science (New York, N.Y.). 366: 1197-1198. PMID 31806801 DOI: 10.1126/Science.Aaz8647  0.368
2019 Mathew D, Kremer KN, Strauch P, Tigyi G, Pelanda R, Torres RM. LPA Is an Inhibitory Receptor That Suppresses CD8 T-Cell Cytotoxic Function via Disruption of Early TCR Signaling. Frontiers in Immunology. 10: 1159. PMID 31231367 DOI: 10.3389/Fimmu.2019.01159  0.456
2019 Greaves SA, Peterson JN, Strauch P, Torres RM, Pelanda R. Active PI3K abrogates central tolerance in high-avidity autoreactive B cells. The Journal of Experimental Medicine. PMID 30948496 DOI: 10.1084/Jem.20181652  0.543
2019 Mathew D, Kremer KN, Torres RM. ARHGEF1 deficiency reveals Gα13-associated GPCRs are critical regulators of human lymphocyte function. The Journal of Clinical Investigation. PMID 30714991 DOI: 10.1172/Jci125893  0.391
2019 Mathew D, Strauch P, Pelanda R, Torres R. Abstract A202: Lysophosphatidic acid impedes the effector function of CD8+ T-cells through LPA5R Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A202  0.454
2018 Greaves SA, Peterson JN, Torres RM, Pelanda R. Corrigendum: Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Frontiers in Immunology. 9: 2218. PMID 30323810 DOI: 10.3389/Fimmu.2018.02218  0.416
2018 Sang A, Danhorn T, Peterson JN, Rankin AL, O'Connor BP, Leach SM, Torres RM, Pelanda R. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus. Nature Communications. 9: 3973. PMID 30266981 DOI: 10.1038/S41467-018-06293-Z  0.584
2018 Agazio AE, Pelanda R, Torres RM. Silencing of TLM B cells by chronic HIV infection. Nature Immunology. 19: 902-903. PMID 30104630 DOI: 10.1038/S41590-018-0191-2  0.451
2018 Atif SM, Gibbings SL, Redente EF, Camp FA, Torres RM, Kedl RM, Henson PM, Jakubzick CV. Immune Surveillance by Natural IgM is Required For Early Neoantigen Recognition and Initiation of Adaptive Immunity. American Journal of Respiratory Cell and Molecular Biology. PMID 29953261 DOI: 10.1165/Rcmb.2018-0159Oc  0.507
2018 Greaves SA, Peterson JN, Torres RM, Pelanda R. Activation of the MEK-ERK Pathway Is Necessary but Not Sufficient for Breaking Central B Cell Tolerance. Frontiers in Immunology. 9: 707. PMID 29686680 DOI: 10.3389/Fimmu.2018.00707  0.529
2017 Lang J, Zhang B, Kelly M, Peterson JN, Barbee J, Freed BM, Di Santo JP, Matsuda JL, Torres RM, Pelanda R. Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice. Blood Advances. 1: 2729-2741. PMID 29296925 DOI: 10.1182/Bloodadvances.2017010090  0.497
2017 Schroeder KM, Agazio A, Torres RM. Immunological tolerance as a barrier to protective HIV humoral immunity. Current Opinion in Immunology. 47: 26-34. PMID 28728075 DOI: 10.1016/J.Coi.2017.06.004  0.414
2017 Schroeder KMS, Agazio A, Strauch PJ, Jones ST, Thompson SB, Harper MS, Pelanda R, Santiago ML, Torres RM. Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies. The Journal of Experimental Medicine. PMID 28698284 DOI: 10.1084/Jem.20161190  0.336
2017 Chisholm CF, Soucie KR, Song JS, Strauch P, Torres RM, Carpenter JF, Ragheb JA, Randolph TW. Immunogenicity of Structurally-Perturbed Hen Egg Lysozyme Adsorbed to Silicone Oil Microdroplets in Wild-Type and Transgenic Mouse Models. Journal of Pharmaceutical Sciences. PMID 28216023 DOI: 10.1016/J.Xphs.2017.02.008  0.312
2017 Li X, Torres R, Kos L. Abstract 1978: Identification of the metastatic cell populations in a spontaneous mouse model of melanoma Cancer Research. 77: 1978-1978. DOI: 10.1158/1538-7445.Am2017-1978  0.318
2016 Hawman DW, Fox JM, Ashbrook AW, May NA, Schroeder KM, Torres RM, Crowe JE, Dermody TS, Diamond MS, Morrison TE. Pathogenic Chikungunya Virus Evades B Cell Responses to Establish Persistence. Cell Reports. PMID 27452455 DOI: 10.1016/J.Celrep.2016.06.076  0.386
2016 Malarkey CS, Gustafson CE, Saifee JF, Torres RM, Churchill ME, Janoff EN. Mechanism of Mitochondrial Transcription Factor A Attenuation of CpG-Induced Antibody Production. Plos One. 11: e0157157. PMID 27280778 DOI: 10.1371/Journal.Pone.0157157  0.458
2016 Born WK, Huang Y, Zeng W, Torres RM, O'Brien RL. A Special Connection between γδ T Cells and Natural Antibodies? Archivum Immunologiae Et Therapiae Experimentalis. PMID 27235134 DOI: 10.1007/S00005-016-0403-0  0.519
2016 Saumyaa, Pujanauski L, Colino J, Flora M, Torres RM, Tuomanen E, Snapper CM. Pneumococcal Surface Protein A Plays a Major Role in Streptococcus pneumoniae-Induced Immunosuppression. Journal of Immunology (Baltimore, Md. : 1950). 196: 3677-85. PMID 27029587 DOI: 10.4049/Jimmunol.1502709  0.758
2016 Chisholm CF, Baker AE, Soucie KR, Torres RM, Carpenter JF, Randolph TW. Silicone Oil Microdroplets Can Induce Antibody Responses Against Recombinant Murine Growth Hormone in Mice. Journal of Pharmaceutical Sciences. PMID 27020987 DOI: 10.1016/J.Xphs.2016.02.019  0.326
2015 Lang J, Ota T, Kelly M, Strauch P, Freed BM, Torres RM, Nemazee D, Pelanda R. Receptor editing and genetic variability in human autoreactive B cells. The Journal of Experimental Medicine. PMID 26694971 DOI: 10.1084/Jem.20151039  0.471
2015 Christie M, Peritt D, Torres RM, Randolph TW, Carpenter JF. The Role of Protein Excipient in Driving Antibody Responses to Erythropoietin. Journal of Pharmaceutical Sciences. PMID 26375484 DOI: 10.1002/Jps.24639  0.346
2014 Christie M, Torres RM, Kedl RM, Randolph TW, Carpenter JF. Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration. Journal of Pharmaceutical Sciences. 103: 128-39. PMID 25133276 DOI: 10.1002/Jps.23794  0.347
2014 Teodorovic LS, Babolin C, Rowland SL, Greaves SA, Baldwin DP, Torres RM, Pelanda R. Activation of Ras overcomes B-cell tolerance to promote differentiation of autoreactive B cells and production of autoantibodies Proceedings of the National Academy of Sciences of the United States of America. 111: E2797-E2806. PMID 24958853 DOI: 10.1073/Pnas.1402159111  0.508
2014 Hu J, Oda SK, Shotts K, Donovan EE, Strauch P, Pujanauski LM, Victorino F, Al-Shami A, Fujiwara Y, Tigyi G, Oravecz T, Pelanda R, Torres RM. Lysophosphatidic acid receptor 5 inhibits B cell antigen receptor signaling and antibody response. Journal of Immunology (Baltimore, Md. : 1950). 193: 85-95. PMID 24890721 DOI: 10.4049/Jimmunol.1300429  0.77
2014 Torres R, Garcia A, Jimenez M, Rodriguez S, Ramirez JC. An integration-defective lentivirus-based resource for site-specific targeting of an edited safe-harbour locus in the human genome. Gene Therapy. 21: 343-52. PMID 24500524 DOI: 10.1038/Gt.2014.1  0.339
2014 Torres RM, Pujanauski L. Broadly neutralizing antibodies Access Science. DOI: 10.1036/1097-8542.Yb140349  0.772
2013 Oda SK, Strauch P, Fujiwara Y, Al-Shami A, Oravecz T, Tigyi G, Pelanda R, Torres RM. Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression. Cancer Immunology Research. 1: 245-55. PMID 24455753 DOI: 10.1158/2326-6066.Cir-13-0043-T  0.774
2013 Saumyaa, Arjunaraja S, Pujanauski L, Colino J, Torres RM, Snapper CM. Immunosuppressive property within the Streptococcus pneumoniae cell wall that inhibits generation of T follicular helper, germinal center, and plasma cell response to a coimmunized heterologous protein. Infection and Immunity. 81: 3426-33. PMID 23817619 DOI: 10.1128/Iai.00688-13  0.797
2013 Fuquay R, Renner B, Kulik L, McCullough JW, Amura C, Strassheim D, Pelanda R, Torres R, Thurman JM. Renal ischemia-reperfusion injury amplifies the humoral immune response. Journal of the American Society of Nephrology : Jasn. 24: 1063-72. PMID 23641055 DOI: 10.1681/Asn.2012060560  0.359
2013 Lang J, Kelly M, Freed BM, McCarter MD, Kedl RM, Torres RM, Pelanda R. Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 190: 2090-101. PMID 23335750 DOI: 10.4049/Jimmunol.1202810  0.506
2013 Pujanauski LM, Janoff EN, McCarter MD, Pelanda R, Torres RM. Mouse marginal zone B cells harbor specificities similar to human broadly neutralizing HIV antibodies. Proceedings of the National Academy of Sciences of the United States of America. 110: 1422-7. PMID 23288906 DOI: 10.1073/Pnas.1213713110  0.801
2013 Swanson CL, Pelanda R, Torres RM. Division of labor during primary humoral immunity. Immunologic Research. 55: 277-86. PMID 22945808 DOI: 10.1007/S12026-012-8372-9  0.783
2013 Rowland SL, Tuttle K, Torres RM, Pelanda R. Antigen and cytokine receptor signals guide the development of the naïve mature B cell repertoire Immunologic Research. 55: 231-240. PMID 22941591 DOI: 10.1007/S12026-012-8366-7  0.505
2013 Guan Y, Torres RM, Hartney JM. The influence of Arhgef1 on pulmonary leukocyte function. Immunologic Research. 55: 162-6. PMID 22941563 DOI: 10.1007/S12026-012-8360-0  0.369
2013 Saumyaa, Arjunaraja S, Pujanauski L, Colino J, Torres RM, Snapper CM. Immunosuppressive property within the streptococcus pneumoniae cell wall that inhibits generation of T follicular helper, germinal center, and plasma cell response to a coimmunized heterologous protein Infection and Immunity. 81: 3426-3433. DOI: 10.1128/IAI.00688-13  0.373
2012 Fournier EM, Velez MG, Leahy K, Swanson CL, Rubtsov AV, Torres RM, Pelanda R. Dual-reactive B cells are autoreactive and highly enriched in the plasmablast and memory B cell subsets of autoimmune mice. The Journal of Experimental Medicine. 209: 1797-812. PMID 22927551 DOI: 10.1084/Jem.20120332  0.801
2012 Larson JD, Thurman JM, Rubtsov AV, Claypool D, Marrack P, van Dyk LF, Torres RM, Pelanda R. Murine gammaherpesvirus 68 infection protects lupus-prone mice from the development of autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 109: E1092-100. PMID 22474381 DOI: 10.1073/Pnas.1203019109  0.744
2012 Pelanda R, Torres RM. Central B-cell tolerance: where selection begins. Cold Spring Harbor Perspectives in Biology. 4: a007146. PMID 22378602 DOI: 10.1101/Cshperspect.A007146  0.515
2012 Teodorovic LS, Riccardi C, Torres RM, Pelanda R. Murine B cell development and antibody responses to model antigens are not impaired in the absence of the TNF receptor GITR. Plos One. 7: e31632. PMID 22328941 DOI: 10.1371/Journal.Pone.0031632  0.598
2011 Hartney JM, Gustafson CE, Bowler RP, Pelanda R, Torres RM. Thromboxane receptor signaling is required for fibronectin-induced matrix metalloproteinase 9 production by human and murine macrophages and is attenuated by the Arhgef1 molecule. The Journal of Biological Chemistry. 286: 44521-31. PMID 22086927 DOI: 10.1074/Jbc.M111.282772  0.356
2011 Torres R, García A, Payá M, Ramirez JC. Non-Integrative Lentivirus Drives High-Frequency cre-Mediated Cassette Exchange in Human Cells Plos One. 6. PMID 21625434 DOI: 10.1371/Journal.Pone.0019794  0.33
2011 Lang J, Weiss N, Freed BM, Torres RM, Pelanda R. Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2rγnull mouse model: a multivariable optimization approach. Clinical Immunology (Orlando, Fla.). 140: 102-16. PMID 21536497 DOI: 10.1016/J.Clim.2011.04.002  0.326
2010 Rowland SL, Leahy KF, Halverson R, Torres RM, Pelanda R. BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling Journal of Immunology. 185: 4570-4581. PMID 20861359 DOI: 10.4049/Jimmunol.1001708  0.515
2010 Swanson CL, Wilson TJ, Strauch P, Colonna M, Pelanda R, Torres RM. Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response. The Journal of Experimental Medicine. 207: 1485-500. PMID 20566717 DOI: 10.1084/Jem.20092695  0.79
2010 Rowland SL, DePersis CL, Torres RM, Pelanda R. Ras activation of Erk restores impaired tonic BCR signaling and rescues immature B cell differentiation Journal of Experimental Medicine. 207: 607-621. PMID 20176802 DOI: 10.1084/Jem.20091673  0.517
2010 Hartney JM, Brown J, Chu HW, Chang LY, Pelanda R, Torres RM. Arhgef1 regulates alpha5beta1 integrin-mediated matrix metalloproteinase expression and is required for homeostatic lung immunity. The American Journal of Pathology. 176: 1157-68. PMID 20093499 DOI: 10.2353/Ajpath.2010.090200  0.729
2010 Donovan EE, Pelanda R, Torres RM. S1P3 confers differential S1P-induced migration by autoreactive and non-autoreactive immature B cells and is required for normal B-cell development. European Journal of Immunology. 40: 688-98. PMID 20039302 DOI: 10.1002/Eji.200939858  0.473
2009 Torres R, Ramirez JC. A Chemokine Targets the Nucleus: Cxcl12-Gamma Isoform Localizes to the Nucleolus in Adult Mouse Heart Plos One. 4. PMID 19859557 DOI: 10.1371/Journal.Pone.0007570  0.36
2009 Colino J, Chattopadhyay G, Sen G, Chen Q, Lees A, Canaday DH, Rubtsov A, Torres R, Snapper CM. Parameters underlying distinct T cell-dependent polysaccharide-specific IgG responses to an intact gram-positive bacterium versus a soluble conjugate vaccine. Journal of Immunology (Baltimore, Md. : 1950). 183: 1551-9. PMID 19570830 DOI: 10.4049/Jimmunol.0900238  0.776
2009 Clambey ET, Torres RM. Activation or suppression? T cell immunity in COPD lungs. Copd. 6: 84-5. PMID 19378220 DOI: 10.1080/15412550902835168  0.385
2008 Rubtsov AV, Swanson CL, Troy S, Strauch P, Pelanda R, Torres RM. TLR agonists promote marginal zone B cell activation and facilitate T-dependent IgM responses. Journal of Immunology (Baltimore, Md. : 1950). 180: 3882-8. PMID 18322196 DOI: 10.4049/Jimmunol.180.6.3882  0.81
2008 Hu J, Strauch P, Rubtsov A, Donovan EE, Pelanda R, Torres RM. Lsc activity is controlled by oligomerization and regulates integrin adhesion. Molecular Immunology. 45: 1825-36. PMID 18157933 DOI: 10.1016/J.Molimm.2007.11.002  0.785
2008 Rowland S, Halverson R, Kane M, Torres R, Pelanda R. Contributions of Antigen and Cytokine Receptor Signals to Immature B cell Survival and Development The Faseb Journal. 22: 378-378. DOI: 10.1096/Fasebj.22.2_Supplement.378  0.477
2007 Chattopadhyay G, Khan AQ, Sen G, Colino J, DuBois W, Rubtsov A, Torres RM, Potter M, Snapper CM. Transgenic expression of Bcl-xL or Bcl-2 by murine B cells enhances the in vivo antipolysaccharide, but not antiprotein, response to intact Streptococcus pneumoniae. Journal of Immunology (Baltimore, Md. : 1950). 179: 7523-34. PMID 18025197 DOI: 10.4049/Jimmunol.179.11.7523  0.807
2007 Velez MG, Kane M, Liu S, Gauld SB, Cambier JC, Torres RM, Pelanda R. Ig allotypic inclusion does not prevent B cell development or response. Journal of Immunology (Baltimore, Md. : 1950). 179: 1049-57. PMID 17617597 DOI: 10.4049/Jimmunol.179.2.1049  0.572
2007 Brown JP, Taube C, Miyahara N, Koya T, Pelanda R, Gelfand EW, Torres RM. Arhgef1 is required by T cells for the development of airway hyperreactivity and inflammation. American Journal of Respiratory and Critical Care Medicine. 176: 10-9. PMID 17463415 DOI: 10.1164/Rccm.200702-270Oc  0.766
2006 Pelanda R, Torres RM. Receptor editing for better or for worse. Current Opinion in Immunology. 18: 184-90. PMID 16460922 DOI: 10.1016/J.Coi.2006.01.005  0.469
2005 Rubtsov A, Strauch P, Digiacomo A, Hu J, Pelanda R, Torres RM. Lsc regulates marginal-zone B cell migration and adhesion and is required for the IgM T-dependent antibody response. Immunity. 23: 527-38. PMID 16286020 DOI: 10.1016/J.Immuni.2005.09.018  0.815
2005 Liu S, Velez MG, Humann J, Rowland S, Conrad FJ, Halverson R, Torres RM, Pelanda R. Receptor editing can lead to allelic inclusion and development of B cells that retain antibodies reacting with high avidity autoantigens. Journal of Immunology (Baltimore, Md. : 1950). 175: 5067-76. PMID 16210610 DOI: 10.4049/Jimmunol.175.8.5067  0.535
2004 Halverson R, Torres RM, Pelanda R. Receptor editing is the main mechanism of B cell tolerance toward membrane antigens. Nature Immunology. 5: 645-50. PMID 15156139 DOI: 10.1038/Ni1076  0.486
2002 Kühn R, Torres RM. Cre/loxP recombination system and gene targeting Methods in Molecular Biology (Clifton, N.J.). 180: 175-204. PMID 11873650 DOI: 10.1385/1-59259-178-7:175  0.301
2000 Fehr T, López-Macías C, Odermatt B, Torres RM, Schubart DB, O'Keefe TL, Matthias P, Hengartner H, Zinkernagel RM. Correlation of anti-viral B cell responses and splenic morphology with expression of B cell-specific molecules. International Immunology. 12: 1275-84. PMID 10967022 DOI: 10.1093/INTIMM/12.9.1275  0.452
1999 Kraus M, Saijo K, Torres RM, Rajewsky K. Ig-alpha cytoplasmic truncation renders immature B cells more sensitive to antigen contact. Immunity. 11: 537-45. PMID 10591179 DOI: 10.1016/S1074-7613(00)80129-6  0.461
1999 Torres RM, Hafen K. A negative regulatory role for Ig-α during B cell development Immunity. 11: 527-536. PMID 10591178 DOI: 10.1016/S1074-7613(00)80128-4  0.498
1999 Loder F, Mutschler B, Ray RJ, Paige CJ, Sideras P, Torres R, Lamers MC, Carsetti R. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. The Journal of Experimental Medicine. 190: 75-89. PMID 10429672 DOI: 10.1084/Jem.190.1.75  0.5
1997 Pelanda R, Schwers S, Sonoda E, Torres RM, Nemazee D, Rajewsky K. Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 7: 765-75. PMID 9430222 DOI: 10.1016/S1074-7613(00)80395-7  0.521
1996 Pelanda R, Schaal S, Torres RM, Rajewsky K. A prematurely expressed Igκ transgene, but not a VκJκ gene segment targeted into the Igκ locus, can rescue B cell development in λ5-deficient mice Immunity. 5: 229-239. PMID 8808678 DOI: 10.1016/S1074-7613(00)80318-0  0.373
1996 Torres RM, Flaswinkel H, Reth M, Rajewsky K. Aberrant B cell development and immune response in mice with a compromised BCR complex Science. 272: 1804-1808. PMID 8650582 DOI: 10.1126/Science.272.5269.1804  0.535
1993 Heath AW, Chang R, Harada N, Santos-Argumedo L, Gordon J, Hannum C, Campbell D, Shanafelt AB, Clark EA, Torres R, Howard M. Antibodies to Murine CD40 Stimulate Normal B Lymphocytes but Inhibit Proliferation of B Lymphoma Cells Cellular Immunology. 152: 468-480. PMID 7504979 DOI: 10.1006/Cimm.1993.1305  0.442
1992 Deans JP, Kanner SB, Torres RM, Ledbetter JA. Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase. European Journal of Immunology. 22: 661-8. PMID 1532148 DOI: 10.1002/Eji.1830220308  0.33
1992 Leprince C, Draves KE, Ledbetter JA, Torres RM, Clark EA. Characterization of molecular components associated with surface immunoglobulin M in human B lymphocytes: Presence of tyrosine and serine/threonine protein kinases European Journal of Immunology. 22: 2093-2099. PMID 1386314 DOI: 10.1002/Eji.1830220820  0.443
1992 Indzhiia LV, Yakovleva LA, Overbaugh J, Licciardi KA, Chikobava MG, Klotz IN, Torres R, Indzhiia VO, Lapin BA, Clark EA. Baboon T cell lymphomas expressing the B cell-associated surface proteins CD40 and Bgp95. Journal of Clinical Immunology. 12: 225-36. PMID 1383259 DOI: 10.1007/Bf00918093  0.465
1987 Valentine MA, Cotner T, Gaur L, Torres R, Clark EA. Expression of the human B-cell surface protein CD20: alteration by phorbol 12-myristate 13-acetate. Proceedings of the National Academy of Sciences of the United States of America. 84: 8085-9. PMID 3500472 DOI: 10.1073/Pnas.84.22.8085  0.45
Low-probability matches (unlikely to be authored by this person)
2014 Rio-Machin A, Maiques-Diaz A, Rodriguez-Perales S, Alvarez S, Salgado RN, Eguileor Á, Torres R, Ramirez JC, Cigudosa JC. Abstract 472: Interactions of the fusion protein Nup98-Hoxa9 with Pbx3, p300 and HDAC1: widening the targeted therapy window in acute myeloid leukemia (AML) Cancer Research. 74: 472-472. DOI: 10.1158/1538-7445.Am2014-472  0.294
2015 Chisholm CF, Nguyen BH, Soucie KR, Torres RM, Carpenter JF, Randolph TW. In Vivo Analysis of the Potency of Silicone Oil Microdroplets as Immunological Adjuvants in Protein Formulations. Journal of Pharmaceutical Sciences. 104: 3681-90. PMID 26190624 DOI: 10.1002/Jps.24573  0.294
2022 Castleman MJ, Stumpf MM, Therrien NR, Smith MJ, Lesteberg KE, Palmer BE, Maloney JP, Janssen WJ, Mould KJ, Beckham JD, Pelanda R, Torres RM. Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells. Frontiers in Immunology. 13: 988125. PMID 36131937 DOI: 10.3389/fimmu.2022.988125  0.29
2016 Herrera-Merchan A, Cuadros M, Rodriguez S, Torres R, Farez E, Medina P. Abstract 976: Long non-coding RNA Fendrr as biomarker for lung cancer Cancer Research. 76: 976-976. DOI: 10.1158/1538-7445.Am2016-976  0.283
2017 Carbone ML, Chadeuf G, Heurtebise-Chrétien S, Prieur X, Quillard T, Goueffic Y, Vaillant N, Rio M, Castan L, Durand M, Baron-Menguy C, Aureille J, Desfrançois J, Tesse A, Torres RM, et al. Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis. The Journal of Clinical Investigation. PMID 29130930 DOI: 10.1172/Jci92702  0.283
2012 Leandro-García LJ, Leskelä S, Inglada-Pérez L, Landa I, de Cubas AA, Maliszewska A, Comino-Méndez I, Letón R, Gómez-Graña Á, Torres R, Ramírez JC, Álvarez S, Rivera J, Martínez C, Lozano ML, et al. Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity. Cancer Research. 72: 4744-52. PMID 22805305 DOI: 10.1158/0008-5472.Can-11-2861  0.271
1982 Bordin S, Torres R, Petra PH. An enzyme-immunoassay (ELISA) for the Sex Steroid-Binding Protein (SBP) of human serum☆ Journal of Steroid Biochemistry. 17: 453-457. PMID 6890129 DOI: 10.1016/0022-4731(82)90641-0  0.27
2010 Guilluy C, Brégeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E, Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G. The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nature Medicine. 16: 183-90. PMID 20098430 DOI: 10.1038/Nm.2079  0.269
2014 Torres R, Martin MC, Garcia A, Cigudosa JC, Ramirez JC, Rodriguez-Perales S. Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR-Cas9 system. Nature Communications. 5: 3964. PMID 24888982 DOI: 10.1038/Ncomms4964  0.262
2019 Bonafont J, Mencía Á, García M, Torres R, Rodríguez S, Carretero M, Chacón-Solano E, Modamio-Høybjør S, Marinas L, León C, Escamez MJ, Hausser I, Del Río M, Murillas R, Larcher F. Clinically Relevant Correction of Recessive Dystrophic Epidermolysis Bullosa by Dual sgRNA CRISPR/Cas9-Mediated Gene Editing. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30930113 DOI: 10.1016/J.Ymthe.2019.03.007  0.258
2019 Alves da Costa T, Lang J, Torres RM, Pelanda R. The development of human immune system mice and their use to study tolerance and autoimmunity. Journal of Translational Autoimmunity. 2: 100021. PMID 32743507 DOI: 10.1016/j.jtauto.2019.100021  0.256
2019 Quintana-Bustamante O, Fañanas-Baquero S, Orman I, Torres R, Duchateau P, Poirot L, Gouble A, Bueren JA, Segovia JC. Gene editing of PKLR gene in human hematopoietic progenitors through 5' and 3' UTR modified TALEN mRNA. Plos One. 14. PMID 31618280 DOI: 10.1371/Journal.Pone.0223775  0.255
2021 Marín-Jiménez JA, Capasso A, Lewis MS, Bagby SM, Hartman SJ, Shulman J, Navarro NM, Yu H, Rivard CJ, Wang X, Barkow JC, Geng D, Kar A, Yingst A, Tufa DM, ... ... Torres RM, et al. Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes. Frontiers in Immunology. 12: 607282. PMID 33854497 DOI: 10.3389/fimmu.2021.607282  0.238
2012 Hartney JM, Chu H, Pelanda R, Torres RM. Sub-chronic exposure to second hand smoke induces airspace leukocyte infiltration and decreased lung elastance. Frontiers in Physiology. 3: 300. PMID 22934051 DOI: 10.3389/Fphys.2012.00300  0.229
2007 Wu Q, Martin RJ, Rino JG, Breed R, Torres RM, Chu HW. IL-23-dependent IL-17 production is essential in neutrophil recruitment and activity in mouse lung defense against respiratory Mycoplasma pneumoniae infection. Microbes and Infection / Institut Pasteur. 9: 78-86. PMID 17198762 DOI: 10.1016/J.Micinf.2006.10.012  0.229
2017 Herrera-Merchan A, Cuadros M, Rodriguez MI, Rodriguez S, Torres R, Estecio M, Coira IF, Loidi C, Saiz M, Carmona-Saez P, Medina PP. The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma. Oncotarget. 11: 1172-1185. DOI: 10.18632/Oncotarget.22154  0.228
2020 Li X, Karras P, Torres R, Rambow F, van den Oord J, Marine JC, Kos L. Disseminated Melanoma Cells Transdifferentiate into Endothelial Cells in Intravascular Niches at Metastatic Sites. Cell Reports. 31: 107765. PMID 32553158 DOI: 10.1016/J.Celrep.2020.107765  0.224
2018 Bonafont J, Mencia A, Del Rio M, Escamez M, Torres R, Hauser-Siller I, Murillas R, Larcher F. LB1544 Highly efficient, permanent ex vivo correction of RDEB via non-viral CRISPR/Cas9 excision of COL7A1 Exon 80 bearing a prevalent mutation Journal of Investigative Dermatology. 138: B13. DOI: 10.1016/J.Jid.2018.06.078  0.203
2015 Torres R, Rodriguez-Perales S, Ramirez JC. The Use of Innovative Tools to Reproduce Human Cancer Translocations: Lessons from the CRISPR/Cas System Current Biotechnology. 3: 273-278. DOI: 10.2174/2211550103666141023221106  0.195
2024 Turner JA, Hakimi A, Lee H, Schowinsky JT, Sippel JM, Siegele BJ, Torres RM, Robinson WA. Autoreactive Antibodies Associated with Castleman Disease Triad. Case Reports in Immunology. 2024: 9382107. PMID 38482465 DOI: 10.1155/2024/9382107  0.177
2013 Chan PK, Torres R, Yandim C, Law PP, Khadayate S, Mauri M, Grosan C, Chapman-Rothe N, Giunti P, Pook M, Festenstein R. Heterochromatinization induced by GAA-repeat hyperexpansion in Friedreich's ataxia can be reduced upon HDAC inhibition by vitamin B3. Human Molecular Genetics. 22: 2662-75. PMID 23474817 DOI: 10.1093/hmg/ddt115  0.174
2023 Torres RM, Cyster J. Lipid mediators in the regulation of innate and adaptive immunity. Immunological Reviews. PMID 37243330 DOI: 10.1111/imr.13228  0.17
2021 Herrmann T, Torres R, Salgado EN, Berciu C, Stoddard D, Nicastro D, Jenni S, Harrison SC. Functional refolding of the penetration protein on a non-enveloped virus. Nature. PMID 33442061 DOI: 10.1038/s41586-020-03124-4  0.161
2020 López-Manzaneda S, Ojeda-Pérez I, Zabaleta N, García-Torralba A, Alberquilla O, Torres R, Sánchez-Domínguez R, Torella L, Olivier E, Mountford J, Ramírez JC, Bueren JA, González-Aseguinolaza G, Segovia JC. and Genetic Disease Modeling via NHEJ-Precise Deletions Using CRISPR-Cas9. Molecular Therapy. Methods & Clinical Development. 19: 426-437. PMID 33294491 DOI: 10.1016/j.omtm.2020.10.007  0.159
2023 Ugalde L, Fañanas S, Torres R, Quintana-Bustamante O, Río P. Clustered regularly interspaced short palindromic repeats/Cas9-mediated gene editing. A promising strategy in hematological disorders. Cytotherapy. PMID 36610813 DOI: 10.1016/j.jcyt.2022.11.014  0.154
2019 Khoshchehreh R, Totonchi M, Carlos Ramirez J, Torres R, Baharvand H, Aicher A, Ebrahimi M, Heeschen C. Epigenetic reprogramming of primary pancreatic cancer cells counteracts their in vivo tumourigenicity. Oncogene. 38: 6226-6239. PMID 31308488 DOI: 10.1038/s41388-019-0871-x  0.147
2008 Torres RM, Imboden J, Schroeder HW. Antigen receptor genes, gene products, and co-receptors Clinical Immunology. 53-77. DOI: 10.1016/B978-0-323-04404-2.10004-1  0.141
2022 Turner JA, Paton EL, Van Gulick R, Stefanoni D, Cendali F, Reisz J, Tobin RP, McCarter M, D'Alessandro A, Torres RM, Robinson WA, Couts KL, Schlaepfer IR. BRAF Modulates Lipid Use and Accumulation. Cancers. 14. PMID 35565240 DOI: 10.3390/cancers14092110  0.136
2023 Guillén-García P, Guillén-Vicente I, Rodríguez-Iñigo E, Guillén-Vicente M, Fernández-Jaén TF, Navarro R, Aboli L, Torres R, Abelow S, López-Alcorocho JM. Cartilage Defect Treatment Using High-Density Autologous Chondrocyte Implantation (HD-ACI). Bioengineering (Basel, Switzerland). 10. PMID 37760185 DOI: 10.3390/bioengineering10091083  0.107
2012 Gelber PE, Torres R, Garcia-Giralt N, Erquicia J, Abat F, Monllau JC. Host serum is not indispensable in collagen performance in viable meniscal transplantation at 4-week incubation. Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the Esska. 20: 1681-8. PMID 22020961 DOI: 10.1007/S00167-011-1722-7  0.099
2023 Mouron S, Bueno MJ, Muñoz M, Torres R, Rodríguez S, Apala JV, Silva J, Sánchez-Bayona R, Manso L, Guerra J, Rodriguez-Lajusticia L, Malon D, Malumbres M, Quintela-Fandino M. p27Kip1 V109G as a biomarker for CDK4/6 inhibitors indication in hormone receptor-positive breast cancer. Jnci Cancer Spectrum. PMID 36806942 DOI: 10.1093/jncics/pkad014  0.096
2009 Gelber PE, Gonzalez G, Torres R, Garcia Giralt N, Caceres E, Monllau JC. Cryopreservation does not alter the ultrastructure of the meniscus. Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the Esska. 17: 639-44. PMID 19225756 DOI: 10.1007/s00167-009-0736-x  0.096
2015 Leonard J, Sen N, Torres R, Sutani T, Jarmuz A, Shirahige K, Aragón L. Condensin Relocalization from Centromeres to Chromosome Arms Promotes Top2 Recruitment during Anaphase. Cell Reports. 13: 2336-44. PMID 26686624 DOI: 10.1016/j.celrep.2015.11.041  0.079
2018 Torres R, Szpiech ZA, Hernandez RD. Human demographic history has amplified the effects of background selection across the genome. Plos Genetics. 14: e1007387. PMID 29912945 DOI: 10.1371/Journal.Pgen.1007387  0.077
2020 Torres R, Stetter MG, Hernandez RD, Ross-Ibarra J. The Temporal Dynamics of Background Selection in Non-equilibrium Populations. Genetics. PMID 32071195 DOI: 10.1534/Genetics.119.302892  0.077
2015 Uricchio LH, Torres R, Witte JS, Hernandez RD. Population genetic simulations of complex phenotypes with implications for rare variant association tests. Genetic Epidemiology. 39: 35-44. PMID 25417809 DOI: 10.1002/Gepi.21866  0.076
2020 Herrera-Merchan A, Cuadros M, Rodriguez MI, Rodriguez S, Torres R, Estecio M, Coira IF, Loidi C, Saiz M, Carmona-Saez P, Medina PP. The value of lncRNA and as a prognostic factor for survival of lung adenocarcinoma. Oncotarget. 11: 1172-1185. PMID 32284793  0.072
2016 Mathias RA, Taub MA, Gignoux CR, Fu W, Musharoff S, O'Connor TD, Vergara C, Torgerson DG, Pino-Yanes M, Shringarpure SS, Huang L, Rafaels N, Boorgula MP, Johnston HR, Ortega VE, ... ... Torres R, et al. A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome. Nature Communications. 7: 12522. PMID 27725671 DOI: 10.1038/Ncomms12522  0.055
2016 Sen N, Leonard J, Torres R, Garcia-Luis J, Palou-Marin G, Aragón L. Physical Proximity of Sister Chromatids Promotes Top2-Dependent Intertwining. Molecular Cell. 64: 134-147. PMID 27716481 DOI: 10.1016/j.molcel.2016.09.007  0.053
2021 Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, et al. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 590: 290-299. PMID 33568819 DOI: 10.1038/s41586-021-03205-y  0.05
2021 Johansen Taber K, Ben-Shachar R, Torres R, Arjunan A, Muzzey D, Kaseniit KE, Goldberg J, Brown H. A guidelines-consistent carrier screening panel that supports equity across diverse populations. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 34906503 DOI: 10.1016/j.gim.2021.09.009  0.042
2022 Weingartz L, Peine B, Humble J, Meyer Z, Torres R, Cox C. Case report: Asymptomatic bronchopulmonary sequestration in an adult with dual celiac and aortic supply. Radiology Case Reports. 17: 4218-4222. PMID 36105834 DOI: 10.1016/j.radcr.2022.08.041  0.04
2012 Torgerson DG, Gignoux CR, Galanter JM, Drake KA, Roth LA, Eng C, Huntsman S, Torres R, Avila PC, Chapela R, Ford JG, Rodríguez-Santana JR, Rodríguez-Cintrón W, Hernandez RD, Burchard EG. Case-control admixture mapping in Latino populations enriches for known asthma-associated genes. The Journal of Allergy and Clinical Immunology. 130: 76-82.e12. PMID 22502797 DOI: 10.1016/J.Jaci.2012.02.040  0.039
2012 Ding D, Scott NM, Thompson EE, Chaiworapongsa T, Torres R, Billstrand C, Murray K, Dexheimer PJ, Ismail M, Kay H, Levy S, Romero R, Lindheimer MD, Nicolae DL, Ober C. Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia. Reproductive Sciences (Thousand Oaks, Calif.). 19: 1343-51. PMID 22902742 DOI: 10.1177/1933719112450337  0.037
2020 Arjunan A, Bellerose H, Torres R, Lazarin G, Taber KJ. Application of a Severity Framework to 176 Genes on an Expanded Carrier Screening Panel [03G] Obstetrics & Gynecology. 135: 71S. DOI: 10.1097/01.aog.0000665208.64209.46  0.031
2016 Shringarpure SS, Mathias RA, Hernandez RD, O'Connor TD, Szpiech ZA, Torres R, De La Vega FM, Bustamante CD, Barnes KC, Taub MA. Using genotype array data to compare multi- and single-sample variant calls and improve variant call sets from deep coverage whole-genome sequencing data. Bioinformatics (Oxford, England). PMID 28035032 DOI: 10.1093/Bioinformatics/Btw786  0.03
2020 Arjunan A, Bellerose H, Torres R, Ben-Shachar R, Hoffman JD, Angle B, Slotnick RN, Simpson BN, Lewis AM, Magoulas PL, Bontempo K, Schulze J, Tarpinian J, Bucher JA, Dineen R, et al. Evaluation and classification of severity for 176 genes on an expanded carrier screening panel. Prenatal Diagnosis. PMID 32474937 DOI: 10.1002/pd.5762  0.025
2019 Torres R, Szpiech ZA, Hernandez RD. Correction: Human demographic history has amplified the effects of background selection across the genome. Plos Genetics. 15: e1007898. PMID 30601801 DOI: 10.1371/Journal.Pgen.1007898  0.025
2021 Arjunan A, Torres R, Gardiner A, Kaseniit KE, Wootton J, Ben-Shachar R, Johansen Taber K. Evaluating the efficacy of three carrier screening workflows designed to identify at-risk carrier couples. Prenatal Diagnosis. 41: 896-904. PMID 33450092 DOI: 10.1002/pd.5900  0.024
2013 Daza EE, Maza J, Torres R. Molecular electrostatic potential as a graph. Current Computer-Aided Drug Design. 9: 272-80. PMID 23700998  0.023
2003 Leyes M, Torres R, Guillén P. Complications of open reduction and internal fixation of ankle fractures. Foot and Ankle Clinics. 8: 131-47, ix. PMID 12760580 DOI: 10.1016/s1083-7515(02)00162-6  0.017
2018 García F, Nürmberger M, Torres R, Crespo J. ARION 1 Reusable Sounding Rocket: The New Microgravity Platform in Europe Advances in Astronautics Science and Technology. 1: 23-30. DOI: 10.1007/s42423-018-0003-7  0.01
2011 Gelber PE, Erquicia J, Abat F, Torres R, Pelfort X, Rodriguez-Baeza A, Alomar X, Monllau JC. Effectiveness of a footprint guide to establish an anatomic femoral tunnel in anterior cruciate ligament reconstruction: computed tomography evaluation in a cadaveric model. Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 27: 817-24. PMID 21624676 DOI: 10.1016/j.arthro.2011.02.004  0.01
2010 Gelber PE, Reina F, Torres R, Monllau JC. Effect of femoral tunnel length on the safety of anterior cruciate ligament graft fixation using cross-pin technique: a cadaveric study. The American Journal of Sports Medicine. 38: 1877-84. PMID 20505057 DOI: 10.1177/0363546510366229  0.01
2010 Gelber PE, Reina F, Torres R, Pelfort X, Tey M, Monllau JC. Anatomic single-bundle anterior cruciate ligament reconstruction from the anteromedial portal: evaluation of transverse femoral fixation in a cadaveric model. Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 26: 651-7. PMID 20434663 DOI: 10.1016/j.arthro.2009.09.020  0.01
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