| Year |
Citation |
Score |
| 2023 |
Shahab SW, Roggeveen CM, Sun J, Kunhiraman H, McSwain LF, Juraschka K, Kumar SA, Saulnier O, Taylor MD, Schniederjan M, Schnepp RW, MacDonald TJ, Kenney AM. The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival. Molecular Oncology. PMID 37341142 DOI: 10.1002/1878-0261.13477 |
0.373 |
|
| 2023 |
Kunhiraman H, McSwain L, Shahab SW, Gershon TR, MacDonald TJ, Kenney AM. IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma. Acta Neuropathologica Communications. 11: 62. PMID 37029430 DOI: 10.1186/s40478-023-01557-2 |
0.415 |
|
| 2021 |
Yuan L, Zhang H, Liu J, Malhotra A, Dey A, Yu B, Jella KK, McSwain LF, Schniederjan MJ, MacDonald TJ. STAT3 is required for Smo-dependent signaling and mediates Smo-targeted treatment resistance and tumorigenesis in Shh medulloblastoma. Molecular Oncology. PMID 34482626 DOI: 10.1002/1878-0261.13097 |
0.348 |
|
| 2021 |
MacDonald TJ, Liu J, Yu B, Malhotra A, Munson J, Park JC, Wang K, Fei B, Bellamkonda R, Arbiser J. Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo. Cancers. 13. PMID 33799550 DOI: 10.3390/cancers13061220 |
0.397 |
|
| 2019 |
Dobson THW, Tao RH, Swaminathan J, Maegawa S, Shaik S, Bravo-Alegria J, Sharma A, Kennis B, Yang Y, Callegari K, Haltom AR, Taylor P, Kogiso M, Qi L, Khatua S, ... ... MacDonald TJ, et al. Transcriptional repressor REST drives lineage stage-specific chromatin compaction at and increases AKT activation in a mouse model of medulloblastoma. Science Signaling. 12. PMID 30670636 DOI: 10.1126/Scisignal.Aan8680 |
0.311 |
|
| 2018 |
Zhu D, Osuka S, Zhang Z, Reichert ZR, Yang L, Kanemura Y, Jiang Y, You S, Zhang H, Devi NS, Bhattacharya D, Takano S, Gillespie GY, Macdonald T, Tan C, et al. BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation. Cancer Cell. 33: 1004-1016.e5. PMID 29894688 DOI: 10.1016/J.Ccell.2018.05.006 |
0.316 |
|
| 2015 |
Bhatia S, Baig NA, Timofeeva O, Pasquale EB, Hirsch K, MacDonald TJ, Dritschilo A, Lee YC, Henkemeyer M, Rood B, Jung M, Wang XJ, Kool M, Rodriguez O, Albanese C, et al. Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization. Oncotarget. 6: 8929-46. PMID 25879388 DOI: 10.18632/Oncotarget.3369 |
0.409 |
|
| 2015 |
McKinney N, Yuan L, Zhang H, Liu J, Cho YJ, Rushing E, Schniederjan M, MacDonald TJ. EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma. Journal of Neuro-Oncology. 121: 109-18. PMID 25258252 DOI: 10.1007/S11060-014-1618-8 |
0.35 |
|
| 2014 |
Petersen W, Liu J, Yuan L, Zhang H, Schneiderjan M, Cho YJ, MacDonald TJ. Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283. Cancer Letters. 354: 68-76. PMID 25107642 DOI: 10.1016/J.Canlet.2014.07.038 |
0.447 |
|
| 2014 |
Kieran MW, Yao X, Macy M, Leary S, Cohen K, MacDonald T, Allen J, Boklan J, Smith A, Nazemi K, Gore L, Trippett T, DiRenzo J, Narendran A, Perentesis J, et al. FINAL RESULTS OF A PROSPECTIVE MULTI-INSTITUTIONAL PHASE II STUDY OF EVEROLIMUS (RAD001), AN MTOR INHIBITOR, IN PEDIATRIC PATIENTS WITH RECURRENT OR PROGRESSIVE LOW-GRADE GLIOMA. A POETIC CONSORTIUM TRIAL Neuro-Oncology. 16: iii27-iii27. DOI: 10.1093/Neuonc/Nou208.15 |
0.423 |
|
| 2013 |
MacDonald TJ, Vezina G, Stewart CF, Turner D, Pierson CR, Chen L, Pollack IF, Gajjar A, Kieran MW. Phase II study of cilengitide in the treatment of refractory or relapsed high-grade gliomas in children: a report from the Children's Oncology Group. Neuro-Oncology. 15: 1438-44. PMID 24014381 DOI: 10.1093/Neuonc/Not058 |
0.347 |
|
| 2013 |
Yuan L, Zhang H, Liu J, Rubin JB, Cho YJ, Shu HK, Schniederjan M, MacDonald TJ. Growth factor receptor-Src-mediated suppression of GRK6 dysregulates CXCR4 signaling and promotes medulloblastoma migration. Molecular Cancer. 12: 18. PMID 23497290 DOI: 10.1186/1476-4598-12-18 |
0.359 |
|
| 2012 |
Macdonald TJ. Hedgehog Pathway in Pediatric Cancers: They're Not Just for Brain Tumors Anymore. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. 605-9. PMID 24451804 DOI: 10.14694/EdBook_AM.2012.32.605 |
0.33 |
|
| 2012 |
Taylor P, Fangusaro J, Rajaram V, Goldman S, Helenowski IB, MacDonald T, Hasselblatt M, Riedemann L, Laureano A, Cooper L, Gopalakrishnan V. REST is a novel prognostic factor and therapeutic target for medulloblastoma. Molecular Cancer Therapeutics. 11: 1713-23. PMID 22848092 DOI: 10.1158/1535-7163.Mct-11-0990 |
0.353 |
|
| 2012 |
Packer RJ, Macdonald T, Vezina G, Keating R, Santi M. Medulloblastoma and primitive neuroectodermal tumors. Handbook of Clinical Neurology. 105: 529-48. PMID 22230517 DOI: 10.1016/B978-0-444-53502-3.00007-0 |
0.355 |
|
| 2011 |
Rafei M, Deng J, Boivin MN, Williams P, Matulis SM, Yuan S, Birman E, Forner K, Yuan L, Castellino C, Boise LH, MacDonald TJ, Galipeau J. A MCP1 fusokine with CCR2-specific tumoricidal activity. Molecular Cancer. 10: 121. PMID 21943176 DOI: 10.1186/1476-4598-10-121 |
0.395 |
|
| 2011 |
Ringer L, Sirajuddin P, Heckler M, Ghosh A, Suprynowicz F, Yenugonda VM, Brown ML, Toretsky JA, Uren A, Lee Y, MacDonald TJ, Rodriguez O, Glazer RI, Schlegel R, Albanese C. VMY-1-103 is a novel CDK inhibitor that disrupts chromosome organization and delays metaphase progression in medulloblastoma cells. Cancer Biology & Therapy. 12: 818-26. PMID 21885916 DOI: 10.4161/Cbt.12.9.17682 |
0.389 |
|
| 2011 |
Beauchamp EM, Ringer L, Bulut G, Sajwan KP, Hall MD, Lee YC, Peaceman D, Ozdemirli M, Rodriguez O, Macdonald TJ, Albanese C, Toretsky JA, Uren A. Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway. The Journal of Clinical Investigation. 121: 148-60. PMID 21183792 DOI: 10.1172/Jci42874 |
0.404 |
|
| 2011 |
Abouantoun TJ, Castellino RC, MacDonald TJ. Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells. Journal of Neuro-Oncology. 101: 215-26. PMID 20524040 DOI: 10.1007/S11060-010-0259-9 |
0.619 |
|
| 2010 |
Yuan L, Santi M, Rushing EJ, Cornelison R, MacDonald TJ. ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration. Clinical & Experimental Metastasis. 27: 481-91. PMID 20526801 DOI: 10.1007/S10585-010-9337-9 |
0.479 |
|
| 2010 |
Becher OJ, Hambardzumyan D, Walker TR, Helmy K, Nazarian J, Albrecht S, Hiner RL, Gall S, Huse JT, Jabado N, MacDonald TJ, Holland EC. Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma. Cancer Research. 70: 2548-57. PMID 20197468 DOI: 10.1158/0008-5472.Can-09-2503 |
0.441 |
|
| 2010 |
Packer RJ, MacDonald T, Vezina G. Central nervous system tumors. Hematology-Oncology Clinics of North America. 24: 87-108. PMID 20113897 DOI: 10.1016/J.Hoc.2009.11.012 |
0.31 |
|
| 2009 |
Smith C, Santi M, Rajan B, Rushing EJ, Choi MR, Rood BR, Cornelison R, MacDonald TJ, Vukmanovic S. A novel role of HLA class I in the pathology of medulloblastoma. Journal of Translational Medicine. 7: 59. PMID 19594892 DOI: 10.1186/1479-5876-7-59 |
0.356 |
|
| 2009 |
Crawford JR, Santi MR, Thorarinsdottir HK, Cornelison R, Rushing EJ, Zhang H, Yao K, Jacobson S, Macdonald TJ. Detection of human herpesvirus-6 variants in pediatric brain tumors: association of viral antigen in low grade gliomas. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 46: 37-42. PMID 19505845 DOI: 10.1016/J.Jcv.2009.05.011 |
0.331 |
|
| 2009 |
Crawford JR, Santi MR, Cornelison R, Sallinen SL, Haapasalo H, MacDonald TJ. Detection of human herpesvirus-6 in adult central nervous system tumors: predominance of early and late viral antigens in glial tumors. Journal of Neuro-Oncology. 95: 49-60. PMID 19424665 DOI: 10.1007/S11060-009-9908-2 |
0.318 |
|
| 2009 |
Abouantoun TJ, MacDonald TJ. Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor. Molecular Cancer Therapeutics. 8: 1137-47. PMID 19417143 DOI: 10.1158/1535-7163.Mct-08-0889 |
0.602 |
|
| 2009 |
Packer RJ, Jakacki R, Horn M, Rood B, Vezina G, MacDonald T, Fisher MJ, Cohen B. Objective response of multiply recurrent low-grade gliomas to bevacizumab and irinotecan. Pediatric Blood & Cancer. 52: 791-5. PMID 19165892 DOI: 10.1002/Pbc.21935 |
0.418 |
|
| 2009 |
Kieran MW, Supko JG, Wallace D, Fruscio R, Poussaint TY, Phillips P, Pollack I, Packer R, Boyett JM, Blaney S, Banerjee A, Geyer R, Friedman H, Goldman S, Kun LE, ... Macdonald T, et al. Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors. Pediatric Blood & Cancer. 52: 169-76. PMID 19065567 DOI: 10.1002/Pbc.21873 |
0.357 |
|
| 2008 |
Nazarian J, Santi M, Hathout Y, Macdonald TJ. Protein profiling of formalin fixed paraffin embedded tissue: Identification of potential biomarkers for pediatric brainstem glioma. Proteomics. Clinical Applications. 2: 915-24. PMID 21136889 DOI: 10.1002/Prca.200780061 |
0.305 |
|
| 2008 |
MacDonald TJ. Aggressive infantile embryonal tumors. Journal of Child Neurology. 23: 1195-204. PMID 18952586 DOI: 10.1177/0883073808321769 |
0.342 |
|
| 2008 |
Thorarinsdottir HK, Santi M, McCarter R, Rushing EJ, Cornelison R, Jales A, MacDonald TJ. Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3386-94. PMID 18519768 DOI: 10.1158/1078-0432.Ccr-07-1616 |
0.48 |
|
| 2008 |
Chen K, Fallen S, Abaan HO, Hayran M, Gonzalez C, Wodajo F, MacDonald T, Toretsky JA, Uren A. Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival. Pediatric Blood & Cancer. 51: 349-55. PMID 18465804 DOI: 10.1002/Pbc.21595 |
0.368 |
|
| 2008 |
MacDonald TJ, Stewart CF, Kocak M, Goldman S, Ellenbogen RG, Phillips P, Lafond D, Poussaint TY, Kieran MW, Boyett JM, Kun LE. Phase I clinical trial of cilengitide in children with refractory brain tumors: Pediatric Brain Tumor Consortium Study PBTC-012. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 919-24. PMID 18281665 DOI: 10.1200/Jco.2007.14.1812 |
0.321 |
|
| 2008 |
Packer RJ, MacDonald T, Vezina G. Central Nervous System Tumors Pediatric Clinics of North America. 55: 121-145. PMID 18242318 DOI: 10.1016/J.Pcl.2007.10.010 |
0.31 |
|
| 2008 |
Choi LM, Rood B, Kamani N, La Fond D, Packer RJ, Santi MR, Macdonald TJ. Feasibility of metronomic maintenance chemotherapy following high-dose chemotherapy for malignant central nervous system tumors. Pediatric Blood & Cancer. 50: 970-5. PMID 17941070 DOI: 10.1002/Pbc.21381 |
0.368 |
|
| 2007 |
Crawford JR, MacDonald TJ, Packer RJ. Medulloblastoma in childhood: new biological advances. The Lancet. Neurology. 6: 1073-85. PMID 18031705 DOI: 10.1016/S1474-4422(07)70289-2 |
0.322 |
|
| 2007 |
Broniscer A, Gururangan S, MacDonald TJ, Goldman S, Packer RJ, Stewart CF, Wallace D, Danks MK, Friedman HS, Poussaint TY, Kun LE, Boyett JM, Gajjar A. Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6712-8. PMID 18006772 DOI: 10.1158/1078-0432.Ccr-07-1016 |
0.31 |
|
| 2007 |
MacDonald TJ, Pollack IF, Okada H, Bhattacharya S, Lyons-Weiler J. Progression-associated genes in astrocytoma identified by novel microarray gene expression data reanalysis. Methods in Molecular Biology (Clifton, N.J.). 377: 203-22. PMID 17634619 DOI: 10.1007/978-1-59745-390-5_13 |
0.362 |
|
| 2007 |
Crawford JR, Santi MR, Vezina G, Myseros JS, Keating RF, LaFond DA, Rood BR, MacDonald TJ, Packer RJ. CNS germ cell tumor (CNSGCT) of childhood: presentation and delayed diagnosis. Neurology. 68: 1668-73. PMID 17502547 DOI: 10.1212/01.Wnl.0000261908.36803.Ac |
0.307 |
|
| 2007 |
Turner CD, Chi S, Marcus KJ, MacDonald T, Packer RJ, Poussaint TY, Vajapeyam S, Ullrich N, Goumnerova LC, Scott RM, Briody C, Chordas C, Zimmerman MA, Kieran MW. Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. Journal of Neuro-Oncology. 82: 95-101. PMID 17031553 DOI: 10.1007/S11060-006-9251-9 |
0.305 |
|
| 2007 |
MacDonald TJ. New Directions in Pediatric Neuro-Oncology Practice: Impact of the Children's Cancer Group Study 9933, a Phase II Study of High-Dose Chemotherapy Before Radiation in Children with Newly Diagnosed High-Grade Astrocytoma Progress in Neurotherapeutics and Neuropsychopharmacology. 2: 109-122. DOI: 10.1017/S1748232106000085 |
0.34 |
|
| 2006 |
Peterson KM, Shao C, McCarter R, MacDonald TJ, Byrne J. An analysis of SEER data of increasing risk of secondary malignant neoplasms among long-term survivors of childhood brain tumors. Pediatric Blood & Cancer. 47: 83-8. PMID 16317732 DOI: 10.1002/Pbc.20690 |
0.334 |
|
| 2006 |
Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, MacDonald T, Rutka J, Guha A, Gajjar A, Curran T, et al. Radial glia cells are candidate stem cells of ependymoma Cancer Cell. 9: 70. DOI: 10.1016/J.Ccr.2005.12.023 |
0.339 |
|
| 2005 |
Thorarinsdottir HK, Rood B, Lafond D, Perez E, Loechelt B, Kamani N, Packer R, MacDonald T. Outcome for children ≤3 years of age with malignant brain or spinal cord tumors treated with high dose chemotherapy with peripheral blood stem cell rescue. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 8552. PMID 27944694 DOI: 10.1200/Jco.2005.23.16_Suppl.8552 |
0.385 |
|
| 2005 |
MacDonald TJ, Arenson EB, Ater J, Sposto R, Bevan HE, Bruner J, Deutsch M, Kurczynski E, Luerssen T, McGuire-Cullen P, O'Brien R, Shah N, Steinbok P, Strain J, Thomson J, et al. Phase II study of high-dose chemotherapy before radiation in children with newly diagnosed high-grade astrocytoma: final analysis of Children's Cancer Group Study 9933. Cancer. 104: 2862-71. PMID 16315242 DOI: 10.1002/Cncr.21593 |
0.332 |
|
| 2005 |
Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, et al. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell. 8: 323-35. PMID 16226707 DOI: 10.1016/J.Ccr.2005.09.001 |
0.382 |
|
| 2005 |
Rood BR, MacDonald TJ. Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches. Journal of Neuro-Oncology. 75: 267-72. PMID 16195804 DOI: 10.1007/S11060-005-6749-5 |
0.321 |
|
| 2005 |
Mintz MB, Sowers R, Brown KM, Hilmer SC, Mazza B, Huvos AG, Meyers PA, Lafleur B, McDonough WS, Henry MM, Ramsey KE, Antonescu CR, Chen W, Healey JH, Daluski A, ... ... Macdonald TJ, et al. An expression signature classifies chemotherapy-resistant pediatric osteosarcoma. Cancer Research. 65: 1748-54. PMID 15753370 DOI: 10.1158/0008-5472.Can-04-2463 |
0.353 |
|
| 2004 |
Rood BR, Macdonald TJ, Packer RJ. Current treatment of medulloblastoma: recent advances and future challenges. Seminars in Oncology. 31: 666-75. PMID 15497120 DOI: 10.1053/J.Seminoncol.2004.07.009 |
0.398 |
|
| 2001 |
MacDonald TJ, Brown KM, LaFleur B, Peterson K, Lawlor C, Chen Y, Packer RJ, Cogen P, Stephan DA. Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. Nature Genetics. 29: 143-52. PMID 11544480 DOI: 10.1038/Ng731 |
0.483 |
|
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