John D. Schuetz - Publications

Affiliations: 
Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Cell Biology, Physiology Biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ. Corrigendum to "Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles" [379 (2019) 55-64]. Experimental Cell Research. PMID 31079852 DOI: 10.1016/j.yexcr.2019.05.002  0.96
2019 O'Reilly C, Cho JH, Qi Q, Peters JL, Fukuda Y, Frase S, Peng J, Schuetz JD, Cheng Y, Yoon SO, Han MJ. Metabolic switching in pluripotent stem cells reorganizes energy metabolism and subcellular organelles. Experimental Cell Research. PMID 30922922 DOI: 10.1016/j.yexcr.2019.03.028  0.96
2017 Boswell-Casteel RC, Fukuda Y, Schuetz JD. ABCB6, an ABC Transporter Impacting Drug Response and Disease. The Aaps Journal. 20: 8. PMID 29192381 DOI: 10.1208/s12248-017-0165-6  0.96
2017 Wijaya J, Fukuda Y, Schuetz JD. Obstacles to Brain Tumor Therapy: Key ABC Transporters. International Journal of Molecular Sciences. 18. PMID 29186899 DOI: 10.3390/ijms18122544  0.96
2017 Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, ... ... Schuetz JD, et al. An unexpected protein interaction promotes drug resistance in leukemia. Nature Communications. 8: 1547. PMID 29146910 DOI: 10.1038/s41467-017-01678-y  0.96
2017 Fukuda Y, Wang Y, Lian S, Lynch J, Nagai S, Fanshawe B, Kandilci A, Janke LJ, Neale G, Fan Y, Sorrentino BP, Roussel MF, Grosveld G, Schuetz JD. Upregulated heme biosynthesis, an exploitable vulnerability in MYCN-driven leukemogenesis. Jci Insight. 2. PMID 28768907 DOI: 10.1172/jci.insight.92409  0.96
2016 Fukuda Y, Cheong PL, Lynch J, Brighton C, Frase S, Kargas V, Rampersaud E, Wang Y, Sankaran VG, Yu B, Ney PA, Weiss MJ, Vogel P, Bond PJ, Ford RC, ... ... Schuetz JD, et al. The severity of hereditary porphyria is modulated by the porphyrin exporter and Lan antigen ABCB6. Nature Communications. 7: 12353. PMID 27507172 DOI: 10.1038/ncomms12353  0.92
2015 Morgan JA, Lynch J, Panetta JC, Wang Y, Frase S, Bao J, Zheng J, Opferman JT, Janke L, Green DM, Chemaitilly W, Schuetz JD. Apoptosome activation, an important molecular instigator in 6-mercaptopurine induced Leydig cell death. Scientific Reports. 5: 16488. PMID 26576726 DOI: 10.1038/srep16488  0.92
2015 Zhang Y, Li F, Wang Y, Pitre A, Fang ZZ, Frank MW, Calabrese C, Krausz KW, Neale G, Frase S, Vogel P, Rock CO, Gonzalez FJ, Schuetz JD. Maternal bile acid transporter deficiency promotes neonatal demise. Nature Communications. 6: 8186. PMID 26416771 DOI: 10.1038/ncomms9186  0.92
2015 Cheepala SB, Pitre A, Fukuda Y, Takenaka K, Zhang Y, Wang Y, Frase S, Pestina T, Gartner TK, Jackson C, Schuetz JD. ABCC4, a plasma membrane transporter modulating platelet aggregation. Blood. PMID 26405223 DOI: 10.1182/blood-2014-08-595942  0.92
2015 Morfouace M, Cheepala S, Jackson S, Fukuda Y, Patel YT, Fatima S, Kawauchi D, Shelat AA, Stewart CF, Sorrentino BP, Schuetz JD, Roussel MF. ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy. Cancer Research. PMID 26199091 DOI: 10.1158/0008-5472.CAN-15-0030  0.92
2015 Sinha C, Ren A, Arora K, Moon CS, Yarlagadda S, Woodrooffe K, Lin S, Schuetz JD, Ziady AG, Naren AP. PKA and actin play critical roles as downstream effectors in MRP4-mediated regulation of fibroblast migration. Cellular Signalling. 27: 1345-55. PMID 25841995 DOI: 10.1016/j.cellsig.2015.03.022  0.92
2015 Moon C, Zhang W, Ren A, Arora K, Sinha C, Yarlagadda S, Woodrooffe K, Schuetz JD, Valasani KR, de Jonge HR, Shanmukhappa SK, Shata MT, Buddington RK, Parthasarathi K, Naren AP. Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea. The Journal of Biological Chemistry. 290: 11246-57. PMID 25762723 DOI: 10.1074/jbc.M114.605410  0.92
2015 Fukuda Y, Lian S, Schuetz JD. Leukemia and ABC Transporters Advances in Cancer Research. 125: 171-196. PMID 25640270 DOI: 10.1016/bs.acr.2014.10.006  0.92
2014 Jin D, Ni TT, Sun J, Wan H, Amack JD, Yu G, Fleming J, Chiang C, Li W, Papierniak A, Cheepala S, Conseil G, Cole SP, Zhou B, Drummond IA, ... Schuetz JD, et al. Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport. Nature Cell Biology. 16: 841-51. PMID 25173977 DOI: 10.1038/ncb3029  0.92
2014 Schuetz JD, Swaan PW, Tweedie DJ. The role of transporters in toxicity and disease Drug Metabolism and Disposition. 42: 541-545. PMID 24598705 DOI: 10.1124/dmd.114.057539  0.92
2014 Murphy AJ, Sarrazy V, Wang N, Bijl N, Abramowicz S, Westerterp M, Welch CB, Schuetz JD, Yvan-Charvet L. Deficiency of ATP-binding cassette transporter B6 in megakaryocyte progenitors accelerates atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 34: 751-8. PMID 24504733 DOI: 10.1161/ATVBAHA.113.302613  0.92
2013 Haslam IS, Pitre A, Schuetz JD, Paus R. Protection against chemotherapy-induced alopecia: targeting ATP-binding cassette transporters in the hair follicle? Trends in Pharmacological Sciences. 34: 599-604. PMID 24100054 DOI: 10.1016/j.tips.2013.09.001  0.92
2013 Furmanski BD, Hu S, Fujita K, Li L, Gibson AA, Janke LJ, Williams RT, Schuetz JD, Sparreboom A, Baker SD. Contribution of ABCC4-mediated gastric transport to the absorption and efficacy of dasatinib. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4359-70. PMID 23794731 DOI: 10.1158/1078-0432.CCR-13-0980  0.92
2013 Fukuda Y, Takenaka K, Sparreboom A, Cheepala SB, Wu CP, Ekins S, Ambudkar SV, Schuetz JD. Human immunodeficiency virus protease inhibitors interact with ATP binding cassette transporter 4/multidrug resistance protein 4: a basis for unanticipated enhanced cytotoxicity. Molecular Pharmacology. 84: 361-71. PMID 23775562 DOI: 10.1124/mol.113.086967  0.96
2013 Cheepala SB, Bao J, Nachagari D, Sun D, Wang Y, Zhong TP, Zhong T, Naren AP, Zheng J, Schuetz JD. Crucial role for phylogenetically conserved cytoplasmic loop 3 in ABCC4 protein expression. The Journal of Biological Chemistry. 288: 22207-18. PMID 23766510 DOI: 10.1074/jbc.M113.476218  0.92
2013 Sinha C, Ren A, Arora K, Moon CS, Yarlagadda S, Zhang W, Cheepala SB, Schuetz JD, Naren AP. Multi-drug resistance protein 4 (MRP4)-mediated regulation of fibroblast cell migration reflects a dichotomous role of intracellular cyclic nucleotides. The Journal of Biological Chemistry. 288: 3786-94. PMID 23264633 DOI: 10.1074/jbc.M112.435925  0.92
2013 Cheepala S, Hulot JS, Morgan JA, Sassi Y, Zhang W, Naren AP, Schuetz JD. Cyclic nucleotide compartmentalization: contributions of phosphodiesterases and ATP-binding cassette transporters. Annual Review of Pharmacology and Toxicology. 53: 231-53. PMID 23072381 DOI: 10.1146/annurev-pharmtox-010611-134609  0.92
2012 Perciavalle RM, Stewart DP, Koss B, Lynch J, Milasta S, Bathina M, Temirov J, Cleland MM, Pelletier S, Schuetz JD, Youle RJ, Green DR, Opferman JT. Anti-apoptotic MCL-1 localizes to the mitochondrial matrix and couples mitochondrial fusion to respiration Nature Cell Biology. 14: 575-583. PMID 22544066 DOI: 10.1038/ncb2488  0.92
2012 Ulrich DL, Lynch J, Wang Y, Fukuda Y, Nachagari D, Du G, Sun D, Fan Y, Tsurkan L, Potter PM, Rehg JE, Schuetz JD. ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity. The Journal of Biological Chemistry. 287: 12679-90. PMID 22294697 DOI: 10.1074/jbc.M111.336180  0.92
2012 Fukuda Y, Schuetz JD. ABC transporters and their role in nucleoside and nucleotide drug resistance Biochemical Pharmacology. 83: 1073-1083. PMID 22285911 DOI: 10.1016/j.bcp.2011.12.042  0.92
2011 Fukuda Y, Aguilar-Bryan L, Vaxillaire M, Dechaume A, Wang Y, Dean M, Moitra K, Bryan J, Schuetz JD. Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8. The Journal of Biological Chemistry. 286: 8481-92. PMID 21199866 DOI: 10.1074/jbc.M110.174516  0.92
2011 Krishnamurthy P, Schuetz JD. The role of ABCG2 and ABCB6 in porphyrin metabolism and cell survival. Current Pharmaceutical Biotechnology. 12: 647-55. PMID 21118089 DOI: 10.2174/138920111795163995  0.92
2010 Li C, Schuetz JD, Naren AP. Tobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: implications for lung cancer. Cancer Letters. 292: 246-53. PMID 20089353 DOI: 10.1016/j.canlet.2009.12.009  0.92
2009 Lynch J, Fukuda Y, Krishnamurthy P, Du G, Schuetz JD. Cell survival under stress is enhanced by a mitochondrial ATP-binding cassette transporter that regulates hemoproteins. Cancer Research. 69: 5560-7. PMID 19549895 DOI: 10.1158/0008-5472.CAN-09-0078  0.92
2008 Kitamura Y, Hirouchi M, Kusuhara H, Schuetz JD, Sugiyama Y. Increasing systemic exposure of methotrexate by active efflux mediated by multidrug resistance-associated protein 3 (Mrp3/Abcc3) Journal of Pharmacology and Experimental Therapeutics. 327: 465-473. PMID 18719291 DOI: 10.1124/jpet.108.140475  0.92
2007 Li C, Krishnamurthy PC, Penmatsa H, Marrs KL, Wang XQ, Zaccolo M, Jalink K, Li M, Nelson DJ, Schuetz JD, Naren AP. Spatiotemporal coupling of cAMP transporter to CFTR chloride channel function in the gut epithelia. Cell. 131: 940-51. PMID 18045536 DOI: 10.1016/j.cell.2007.09.037  0.92
2007 Takenaka K, Morgan JA, Scheffer GL, Adachi M, Stewart CF, Sun D, Leggas M, Ejendal KF, Hrycyna CA, Schuetz JD. Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Cancer Research. 67: 6965-72. PMID 17638908 DOI: 10.1158/0008-5472.CAN-06-4720  0.92
2007 Krishnamurthy P, Xie T, Schuetz JD. The role of transporters in cellular heme and porphyrin homeostasis. Pharmacology & Therapeutics. 114: 345-58. PMID 17368550 DOI: 10.1016/j.pharmthera.2007.02.001  0.92
2007 de Wolf CJ, Yamaguchi H, van der Heijden I, Wielinga PR, Hundscheid SL, Ono N, Scheffer GL, de Haas M, Schuetz JD, Wijnholds J, Borst P. cGMP transport by vesicles from human and mouse erythrocytes. The Febs Journal. 274: 439-50. PMID 17229149 DOI: 10.1111/j.1742-4658.2006.05591.x  0.92
2006 Kleemann P, Casper B, Huber M, Schuetz JD, Lohoff M. Multidrug-resistance-associated protein 1 (Mrp1) is probably not required for murine Th cell activation International Immunology. 18: 1603-1606. PMID 17008412 DOI: 10.1093/intimm/dxl094  0.92
2006 Krishnamurthy PC, Du G, Fukuda Y, Sun D, Sampath J, Mercer KE, Wang J, Sosa-Pineda B, Murti KG, Schuetz JD. Identification of a mammalian mitochondrial porphyrin transporter. Nature. 443: 586-9. PMID 17006453 DOI: 10.1038/nature05125  0.92
2006 Lamba JK, Chen X, Lan LB, Kim JW, Wei Wang X, Relling MV, Kazuto Y, Watkins PB, Strom S, Sun D, Schuetz JD, Schuetz EG. Increased CYP3A4 copy number in TONG/HCC cells but not in DNA from other humans. Pharmacogenetics and Genomics. 16: 415-27. PMID 16708050 DOI: 10.1097/01.fpc.0000194421.35641.70  0.92
2006 Leggas M, Panetta JC, Zhuang Y, Schuetz JD, Johnston B, Bai F, Sorrentino B, Zhou S, Houghton PJ, Stewart CF. Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo. Cancer Research. 66: 4802-7. PMID 16651435 DOI: 10.1158/0008-5472.CAN-05-2915  0.92
2006 Mennone A, Soroka CJ, Cai SY, Harry K, Adachi M, Hagey L, Schuetz JD, Boyer JL. Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology (Baltimore, Md.). 43: 1013-21. PMID 16628672 DOI: 10.1002/hep.21158  0.92
2006 Johnson BM, Zhang P, Schuetz JD, Brouwer KL. Characterization of transport protein expression in multidrug resistance-associated protein (Mrp) 2-deficient rats. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 556-62. PMID 16204465 DOI: 10.1124/dmd.105.005793  0.92
2005 Krishnamurthy P, Schuetz JD. The ABC transporter Abcg2/Bcrp: role in hypoxia mediated survival. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 18: 349-58. PMID 16158227 DOI: 10.1007/s10534-005-3709-7  0.92
2005 Masson D, Lagrost L, Athias A, Gambert P, Brimer-Cline C, Lan L, Schuetz JD, Schuetz EG, Assem M. Expression of the pregnane X receptor in mice antagonizes the cholic acid-mediated changes in plasma lipoprotein profile Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 2164-2169. PMID 16123326 DOI: 10.1161/01.ATV.0000183674.88817.fb  0.92
2005 Ozvegy-Laczka C, Várady G, Köblös G, Ujhelly O, Cervenak J, Schuetz JD, Sorrentino BP, Koomen GJ, Váradi A, Német K, Sarkadi B. Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of Biological Chemistry. 280: 4219-27. PMID 15557326 DOI: 10.1074/jbc.M411338200  0.92
2004 Stewart CF, Leggas M, Schuetz JD, Panetta JC, Cheshire PJ, Peterson J, Daw N, Jenkins JJ, Gilbertson R, Germain GS, Harwood FC, Houghton PJ. Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice. Cancer Research. 64: 7491-9. PMID 15492275 DOI: 10.1158/0008-5472.CAN-04-0096  0.92
2004 Leggas M, Adachi M, Scheffer GL, Sun D, Wielinga P, Du G, Mercer KE, Zhuang Y, Panetta JC, Johnston B, Scheper RJ, Stewart CF, Schuetz JD. Mrp4 confers resistance to topotecan and protects the brain from chemotherapy. Molecular and Cellular Biology. 24: 7612-21. PMID 15314169 DOI: 10.1128/MCB.24.17.7612-7621.2004  0.92
2004 Zhang Y, Schuetz JD, Elmquist WF, Miller DW. Plasma membrane localization of multidrug resistance-associated protein homologs in brain capillary endothelial cells. The Journal of Pharmacology and Experimental Therapeutics. 311: 449-55. PMID 15218051 DOI: 10.1124/jpet.104.068528  0.92
2004 Houghton PJ, Germain GS, Harwood FC, Schuetz JD, Stewart CF, Buchdunger E, Traxler P. Imatinib mesylate is a potent inhibitor of the ABCG2 (BCRP) transporter and reverses resistance to topotecan and SN-38 in vitro. Cancer Research. 64: 2333-7. PMID 15059881 DOI: 10.1158/0008-5472.CAN-03-3344  0.92
2004 Krishnamurthy P, Ross DD, Nakanishi T, Bailey-Dell K, Zhou S, Mercer KE, Sarkadi B, Sorrentino BP, Schuetz JD. The stem cell marker Bcrp/ABCG2 enhances hypoxic cell survival through interactions with heme. The Journal of Biological Chemistry. 279: 24218-25. PMID 15044468 DOI: 10.1074/jbc.M313599200  0.92
2004 Denk GU, Soroka CJ, Takeyama Y, Chen WS, Schuetz JD, Boyer JL. Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat Journal of Hepatology. 40: 585-591. PMID 15030973 DOI: 10.1016/j.jhep.2003.12.001  0.92
2004 Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. The Journal of Biological Chemistry. 279: 22250-7. PMID 15004017 DOI: 10.1074/jbc.M314111200  0.92
2003 Wagner M, Fickert P, Zollner G, Fuchsbichler A, Silbert D, Tsybrovskyy O, Zatloukal K, Guo GL, Schuetz JD, Gonzalez FJ, Marschall HU, Denk H, Trauner M. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology. 125: 825-38. PMID 12949728 DOI: 10.1016/S0016-5085(03)01068-0  0.92
2003 Wierdl M, Wall A, Morton CL, Sampath J, Danks MK, Schuetz JD, Potter PM. Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance. Molecular Pharmacology. 64: 279-88. PMID 12869632 DOI: 10.1124/mol.64.2.279  0.92
2003 Zamber CP, Lamba JK, Yasuda K, Farnum J, Thummel K, Schuetz JD, Schuetz EG. Natural allelic variants of breast cancer resistance protein (BCRP) and their relationship to BCRP expression in human intestine. Pharmacogenetics. 13: 19-28. PMID 12544509 DOI: 10.1097/00008571-200301000-00004  0.92
2003 Wierdl M, Morton CL, Harris LC, Danks MK, Schuetz JD, Potter PM. p53-mediated regulation of expression of a rabbit liver carboxylesterase confers sensitivity to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (CPT-11). The Journal of Pharmacology and Experimental Therapeutics. 304: 699-705. PMID 12538824 DOI: 10.1124/jpet.102.044149  0.92
2003 Zelcer N, Reid G, Wielinga P, Kuil A, van der Heijden I, Schuetz JD, Borst P. Steroid and bile acid conjugates are substrates of human multidrug-resistance protein (MRP) 4 (ATP-binding cassette C4). The Biochemical Journal. 371: 361-7. PMID 12523936 DOI: 10.1042/BJ20021886  0.92
2003 Lamba JK, Adachi M, Sun D, Tammur J, Schuetz EG, Allikmets R, Schuetz JD. Nonsense mediated decay downregulates conserved alternatively spliced ABCC4 transcripts bearing nonsense codons. Human Molecular Genetics. 12: 99-109. PMID 12499391 DOI: 10.1093/hmg/ddg011  0.92
2002 Adachi M, Reid G, Schuetz JD. Therapeutic and biological importance of getting nucleotides out of cells: A case for the ABC transporters, MRP4 and 5 Advanced Drug Delivery Reviews. 54: 1333-1342. PMID 12406648 DOI: 10.1016/S0169-409X(02)00166-7  0.92
2002 Yasuda K, Lan LB, Sanglard D, Furuya K, Schuetz JD, Schuetz EG. Interaction of cytochrome P450 3A inhibitors with P-glycoprotein Journal of Pharmacology and Experimental Therapeutics. 303: 323-332. PMID 12235267 DOI: 10.1124/jpet.102.037549  0.92
2002 Zhou S, Morris JJ, Barnes Y, Lan L, Schuetz JD, Sorrentino BP. Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 12339-44. PMID 12218177 DOI: 10.1073/pnas.192276999  0.92
2002 Ekins S, Kim RB, Leake BF, Dantzig AH, Schuetz EG, Lan LB, Yasuda K, Shepard RL, Winter MA, Schuetz JD, Wikel JH, Wrighton SA. Application of three-dimensional quantitative structure-activity relationships of P-glycoprotein inhibitors and substrates. Molecular Pharmacology. 61: 974-81. PMID 11961114 DOI: 10.1124/mol.61.5.974  0.92
2002 Ekins S, Kim RB, Leake BF, Dantzig AH, Schuetz EG, Lan LB, Yasuda K, Shepard RL, Winter MA, Schuetz JD, Wikel JH, Wrighton SA. Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. Molecular Pharmacology. 61: 964-73. PMID 11961113 DOI: 10.1124/mol.61.5.964  0.92
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