Eugenia Spanopoulou - Publications

Affiliations: 
Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Immunology, Molecular Biology

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Schatz DG, Spanopoulou E. Biochemistry of V(D)J recombination. Current Topics in Microbiology and Immunology. 290: 49-85. PMID 16480039 DOI: 10.1007/3-540-26363-2_4  0.537
2000 Gomez CA, Ptaszek LM, Villa A, Bozzi F, Sobacchi C, Brooks EG, Notarangelo LD, Spanopoulou E, Pan ZQ, Vezzoni P, Cortes P, Santagata S. Mutations in conserved regions of the predicted RAG2 kelch repeats block initiation of V(D)J recombination and result in primary immunodeficiencies. Molecular and Cellular Biology. 20: 5653-64. PMID 10891502 DOI: 10.1128/Mcb.20.15.5653-5664.2000  0.59
2000 Aidinis V, Dias DC, Gomez CA, Bhattacharyya D, Spanopoulou E, Santagata S. Definition of minimal domains of interaction within the recombination-activating genes 1 and 2 recombinase complex. Journal of Immunology (Baltimore, Md. : 1950). 164: 5826-32. PMID 10820261 DOI: 10.4049/Jimmunol.164.11.5826  0.598
1999 Aidinis V, Bonaldi T, Beltrame M, Santagata S, Bianchi ME, Spanopoulou E. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2. Molecular and Cellular Biology. 19: 6532-42. PMID 10490593 DOI: 10.1128/Mcb.19.10.6532  0.641
1999 Santagata S, Bhattacharyya D, Wang FH, Singha N, Hodtsev A, Spanopoulou E. Molecular cloning and characterization of a mouse homolog of bacterial ClpX, a novel mammalian class II member of the Hsp100/Clp chaperone family. The Journal of Biological Chemistry. 274: 16311-9. PMID 10347188 DOI: 10.1074/Jbc.274.23.16311  0.522
1999 van Ewijk W, Wang B, Hollander G, Kawamoto H, Spanopoulou E, Itoi M, Amagai T, Jiang YF, Germeraad WT, Chen WF, Katsura Y. Thymic microenvironments, 3-D versus 2-D? Seminars in Immunology. 11: 57-64. PMID 9950752 DOI: 10.1006/Smim.1998.0158  0.324
1998 Santagata S, Aidinis V, Spanopoulou E. The effect of Me2+ cofactors at the initial stages of V(D)J recombination. The Journal of Biological Chemistry. 273: 16325-31. PMID 9632694 DOI: 10.1074/Jbc.273.26.16325  0.628
1998 Villa A, Santagata S, Bozzi F, Giliani S, Frattini A, Imberti L, Gatta LB, Ochs HD, Schwarz K, Notarangelo LD, Vezzoni P, Spanopoulou E. Partial V(D)J recombination activity leads to Omenn syndrome. Cell. 93: 885-96. PMID 9630231 DOI: 10.1016/S0092-8674(00)81448-8  0.589
1998 Zheng B, Han S, Spanopoulou E, Kelsoe G. Immunoglobulin gene hypermutation in germinal centers is independent of the RAG-1 V(D)J recombinase. Immunological Reviews. 162: 133-41. PMID 9602359 DOI: 10.1111/j.1600-065X.1998.tb01436.x  0.439
1998 Hodtsev AS, Choi Y, Spanopoulou E, Posnett DN. Mycoplasma superantigen is a CDR3-dependent ligand for the T cell antigen receptor. The Journal of Experimental Medicine. 187: 319-27. PMID 9449712 DOI: 10.1084/Jem.187.3.319  0.376
1997 McMahan CJ, Difilippantonio MJ, Rao N, Spanopoulou E, Schatz DG. A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity. Molecular and Cellular Biology. 17: 4544-52. PMID 9234712 DOI: 10.1128/Mcb.17.8.4544  0.402
1996 Spanopoulou E. Cellular and molecular analysis of lymphoid development using Rag-deficient mice. International Reviews of Immunology. 13: 257-88. PMID 8884425 DOI: 10.3109/08830189609061752  0.414
1996 Spanopoulou E, Zaitseva F, Wang FH, Santagata S, Baltimore D, Panayotou G. The homeodomain region of Rag-1 reveals the parallel mechanisms of bacterial and V(D)J recombination. Cell. 87: 263-76. PMID 8861910 DOI: 10.1016/S0092-8674(00)81344-6  0.638
1996 Difilippantonio MJ, McMahan CJ, Eastman QM, Spanopoulou E, Schatz DG. RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination. Cell. 87: 253-62. PMID 8861909 DOI: 10.1016/S0092-8674(00)81343-4  0.557
1995 Spanopoulou E, Cortes P, Shih C, Huang CM, Silver DP, Svec P, Baltimore D. Localization, interaction, and RNA binding properties of the V(D)J recombination-activating proteins RAG1 and RAG2. Immunity. 3: 715-26. PMID 8777717 DOI: 10.1016/1074-7613(95)90061-6  0.428
1995 Antoniou M, de Boer E, Spanopoulou E, Imam A, Grosveld F. TBP binding and the rate of transcription initiation from the human beta-globin gene. Nucleic Acids Research. 23: 3473-80. PMID 7567458 DOI: 10.1093/Nar/23.17.3473  0.331
1993 Silver DP, Spanopoulou E, Mulligan RC, Baltimore D. Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. Proceedings of the National Academy of Sciences of the United States of America. 90: 6100-4. PMID 8327489 DOI: 10.1073/Pnas.90.13.6100  0.426
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