Fernand Labrie - Publications

Affiliations: 
Universite Laval (Canada) 
Area:
Animal Physiology Biology, Oncology, Molecular Biology

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Year Citation  Score
2018 Li T, Zhu D, Labrie F, Lin S. CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH Dual-Site Inhibitor EM-139 Health. 10: 1079-1089. DOI: 10.2210/Pdb6Dtp/Pdb  0.301
2016 Labrie F, Martel C. A low dose (6.5 mg) of intravaginal DHEA permits a strictly local action while maintaining all serum estrogens or androgens as well as their metabolites within normal values. Hormone Molecular Biology and Clinical Investigation. PMID 27997350 DOI: 10.1515/Hmbci-2016-0042  0.328
2016 Labrie F, Martel C, Pelletier G. Is vulvovaginal atrophy due to a lack of both estrogens and androgens? Menopause (New York, N.Y.). PMID 27875388 DOI: 10.1097/Gme.0000000000000768  0.342
2016 Martel C, Labrie F, Archer DF, Ke Y, Gonthier R, Simard JN, Lavoie L, Vaillancourt M, Montesino M, Balser J, Moyneur É. Serum steroid concentrations remain within normal postmenopausal values in women receiving daily 6.5mg intravaginal prasterone for 12weeks. The Journal of Steroid Biochemistry and Molecular Biology. 159: 142-53. PMID 26972555 DOI: 10.1016/J.Jsbmb.2016.03.016  0.35
2015 Maliqueo M, Benrick A, Alvi A, Johansson J, Sun M, Labrie F, Ohlsson C, Stener-Victorin E. Circulating gonadotropins and ovarian adiponectin system are modulated by acupuncture independently of sex steroid or β-adrenergic action in a female hyperandrogenic rat model of polycystic ovary syndrome. Molecular and Cellular Endocrinology. 412: 159-69. PMID 25963796 DOI: 10.1016/J.Mce.2015.04.026  0.373
2015 Labrie F. Postmenopausal cell and tissue sex-hormone metabolism: mechanisms of intracrinology. Climacteric : the Journal of the International Menopause Society. 18: 101-2. PMID 25541856 DOI: 10.3109/13697137.2015.993530  0.305
2015 Labrie F. Prostate cancer: Bicalutamide dose increase in castration-resistant disease. Nature Reviews. Urology. 12: 132-3. PMID 25487048 DOI: 10.1038/Nrurol.2014.334  0.313
2015 Labrie F. Combined blockade of testicular and locally made androgens in prostate cancer: a highly significant medical progress based upon intracrinology. The Journal of Steroid Biochemistry and Molecular Biology. 145: 144-56. PMID 24925260 DOI: 10.1016/J.Jsbmb.2014.05.012  0.376
2014 Bertin J, Ouellet J, Dury AY, Pelletier G, Labrie F. Expression of the estrogen receptors and steroidogenic enzymes involved in estradiol formation in the monkey vagina. American Journal of Obstetrics and Gynecology. 211: 499.e1-9. PMID 24928055 DOI: 10.1016/J.Ajog.2014.06.017  0.338
2014 Bertin J, Dury AY, Ouellet J, Pelletier G, Labrie F. Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction. The Journal of Sexual Medicine. 11: 1949-61. PMID 24919541 DOI: 10.1111/Jsm.12589  0.34
2013 Johansson J, Redman L, Veldhuis PP, Sazonova A, Labrie F, Holm G, Johannsson G, Stener-Victorin E. Acupuncture for ovulation induction in polycystic ovary syndrome: a randomized controlled trial. American Journal of Physiology. Endocrinology and Metabolism. 304: E934-43. PMID 23482444 DOI: 10.1152/Ajpendo.00039.2013  0.325
2013 Maliqueo M, Sun M, Johansson J, Benrick A, Labrie F, Svensson H, Lönn M, Duleba AJ, Stener-Victorin E. Continuous administration of a P450 aromatase inhibitor induces polycystic ovary syndrome with a metabolic and endocrine phenotype in female rats at adult age. Endocrinology. 154: 434-45. PMID 23183180 DOI: 10.1210/En.2012-1693  0.329
2012 Calvo E, Luu-The V, Belleau P, Martel C, Labrie F. Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland. Breast Cancer Research and Treatment. 134: 625-47. PMID 22678160 DOI: 10.1007/S10549-012-2104-7  0.33
2012 Gauthier S, Martel C, Labrie F. Steroid derivatives as pure antagonists of the androgen receptor. The Journal of Steroid Biochemistry and Molecular Biology. 132: 93-104. PMID 22449547 DOI: 10.1016/J.Jsbmb.2012.02.006  0.395
2012 Labrie F, Simard J, Luu-The V, Bélanger A, Pelletier G. Structure, function and tissue-specific gene expression of 3β-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues. The Journal of Steroid Biochemistry and Molecular Biology. 43: 805-26. PMID 22217825 DOI: 10.1016/0960-0760(92)90308-6  0.317
2012 Labrie Y, Plourde K, Ouellet J, Ouellette G, Martel C, Labrie F, Pelletier G, Durocher F. Spatiotemporal Expression Pattern of Gadd45g Signaling Pathway Components in the Mouse Uterus Following Hormonal Steroid Treatments Endocrinology and Metabolic Syndrome. 2012: 1-10. DOI: 10.4172/2161-1017.S4-005  0.366
2012 Calvo E, Luu-The V, Martel C, Labrie F. Abstract P2-06-03: Specific Transcriptional Response of Four Blockers of Estrogen Receptors on Estrogen-Modulated Genes in ZR-75-1 Breast Cancer Xenografts Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-06-03  0.338
2011 Johansson P, Johansson JO, Labrie F, Mattsson N, Hansson O, Blennow K, Zetterberg H, Wallin A, Ohlsson C, Svensson J. Mild dementia is associated with increased adrenal secretion of cortisol and precursor sex steroids in women. Clinical Endocrinology. 75: 301-8. PMID 21521348 DOI: 10.1111/J.1365-2265.2011.04082.X  0.301
2011 Lu L, Zhao G, Luu-The V, Ouellet J, Fan Z, Labrie F, Pelletier G. Expression of 11β-hydroxysteroid dehydrogenase type 1 in breast cancer and adjacent non-malignant tissue. An immunocytochemical study. Pathology Oncology Research : Por. 17: 627-32. PMID 21267686 DOI: 10.1007/S12253-011-9361-3  0.319
2010 Labrie F. Intravaginal DHEA, by a strictly local action, exerts beneficial effects on both vaginal atrophy symptoms and sexual dysfunction. Hormone Molecular Biology and Clinical Investigation. 4: 499-507. PMID 25961226 DOI: 10.1515/Hmbci.2010.064  0.36
2010 Zhao G, Lu L, Luu-The V, Fan Z, Labrie F, Pelletier G. Expression of 5α-reductase type 1 in breast cancer and adjacent non-malignant tissue: an immunohistochemical study. Hormone Molecular Biology and Clinical Investigation. 3: 411-5. PMID 25961212 DOI: 10.1515/Hmbci.2010.046  0.319
2010 Yamana K, Labrie F, Luu-The V. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride. Hormone Molecular Biology and Clinical Investigation. 2: 293-9. PMID 25961201 DOI: 10.1515/Hmbci.2010.035  0.357
2010 Berger L, El-Alfy M, Martel C, Labrie F. Effect of long-term topical application of dehydroepiandrosterone (DHEA) and oral estrogens on morphology, cell proliferation, procollagen A1 and androgen receptor levels in rat skin. Hormone Molecular Biology and Clinical Investigation. 2: 267-75. PMID 25961198 DOI: 10.1515/Hmbci.2010.026  0.351
2010 Labrie F, Martel C, Gauthier S, Pelletier G, Sancéau JY. Effect of toremifene and ospemifene, compared to acolbifene, on estrogen-sensitive parameters in rat and human uterine tissues. Hormone Molecular Biology and Clinical Investigation. 1: 139-46. PMID 25961189 DOI: 10.1515/Hmbci.2010.016  0.361
2010 Enright BP, Leach MW, Pelletier G, LaBrie F, McIntyre BS, Losco PE. Effects of an antagonist of neurokinin receptors 1, 2 and 3 on reproductive hormones in male beagle dogs. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 89: 517-25. PMID 21086439 DOI: 10.1002/Bdrb.20274  0.378
2010 Lee DM, Ulubaev A, Tajar A, Pye SR, Pendleton N, Purandare N, O'Neill TW, O'Connor DB, Labrie F, Platt H, Payne D, Bartfai G, Boonen S, Casanueva FF, Finn JD, et al. Endogenous hormones, androgen receptor CAG repeat length and fluid cognition in middle-aged and older men: results from the European Male Ageing Study. European Journal of Endocrinology / European Federation of Endocrine Societies. 162: 1155-64. PMID 20231367 DOI: 10.1530/Eje-09-0970  0.345
2010 Huhtaniemi IT, Pye SR, Holliday KL, Thomson W, O'Neill TW, Platt H, Payne D, John SL, Jiang M, Bartfai G, Boonen S, Casanueva FF, Finn JD, Forti G, Giwercman A, ... ... Labrie F, et al. Effect of polymorphisms in selected genes involved in pituitary-testicular function on reproductive hormones and phenotype in aging men Journal of Clinical Endocrinology and Metabolism. 95: 1898-1908. PMID 20173016 DOI: 10.1210/Jc.2009-2071  0.368
2010 Li S, Han B, Liu G, Li S, Ouellet J, Labrie F, Pelletier G. Immunocytochemical localization of sex steroid hormone receptors in normal human mammary gland. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 58: 509-15. PMID 20026671 DOI: 10.1369/Jhc.2009.954644  0.367
2009 Lévesque MH, El-Alfy M, Cusan L, Labrie F. Androgen receptor as a potential sign of prostate cancer metastasis. The Prostate. 69: 1704-11. PMID 19670238 DOI: 10.1002/Pros.21021  0.337
2009 Li Z, Luu-The V, Poisson-Paré D, Ouellet J, Li S, Labrie F, Pelletier G. Expression of enzymes involved in synthesis and metabolism of estradiol in human breast as studied by immunocytochemistry and in situ hybridization. Histology and Histopathology. 24: 273-82. PMID 19130396 DOI: 10.14670/Hh-24.273  0.326
2009 Ma C, Yoshioka M, Boivin A, Gan L, Takase Y, Labrie F, St-Amand J. Atlas of dihydrotestosterone actions on the transcriptome of prostate in vivo. The Prostate. 69: 293-316. PMID 19023869 DOI: 10.1002/Pros.20883  0.35
2009 Labrie F, Cusan L, Gomez JL, Côté I, Bérubé R, Bélanger P, Martel C, Labrie C. Effect of one-week treatment with vaginal estrogen preparations on serum estrogen levels in postmenopausal women. Menopause (New York, N.Y.). 16: 30-6. PMID 18820592 DOI: 10.1097/Gme.0B013E31817B6132  0.333
2009 Bydal P, Luu-The V, Labrie F, Poirier D. Steroidal lactones as inhibitors of 17beta-hydroxysteroid dehydrogenase type 5: chemical synthesis, enzyme inhibitory activity, and assessment of estrogenic and androgenic activities. European Journal of Medicinal Chemistry. 44: 632-44. PMID 18472187 DOI: 10.1016/J.Ejmech.2008.03.020  0.398
2008 Han B, Li S, Song D, Poisson-Paré D, Liu G, Luu-The V, Ouellet J, Li S, Labrie F, Pelletier G. Expression of 17beta-hydroxysteroid dehydrogenase type 2 and type 5 in breast cancer and adjacent non-malignant tissue: a correlation to clinicopathological parameters. The Journal of Steroid Biochemistry and Molecular Biology. 112: 194-200. PMID 18996480 DOI: 10.1016/J.Jsbmb.2008.10.004  0.314
2008 Faucher F, Cantin L, Luu-The V, Labrie F, Breton R. The crystal structure of human Δ4-3-ketosteroid 5β-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism Biochemistry. 47: 8261-8270. PMID 18624455 DOI: 10.1021/Bi800572S  0.315
2008 Labrie F, Cusan L, Gomez JL, Martel C, Bérubé R, Bélanger P, Chaussade V, Deloche C, Leclaire J. Changes in serum DHEA and eleven of its metabolites during 12-month percutaneous administration of DHEA. The Journal of Steroid Biochemistry and Molecular Biology. 110: 1-9. PMID 18359622 DOI: 10.1016/J.Jsbmb.2008.02.003  0.327
2008 Berger L, El-Alfy M, Labrie F. Effects of intravaginal dehydroepiandrosterone on vaginal histomorphology, sex steroid receptor expression and cell proliferation in the rat. The Journal of Steroid Biochemistry and Molecular Biology. 109: 67-80. PMID 18242978 DOI: 10.1016/J.Jsbmb.2007.09.023  0.381
2008 Pelletier G, Labrie C, Martel C, Labrie F. Chronic administration of dehydroepiandrosterone (DHEA) to female monkey and rat has no effect on mammary gland histology Journal of Steroid Biochemistry and Molecular Biology. 108: 102-108. PMID 17933518 DOI: 10.1016/J.Jsbmb.2007.07.002  0.365
2007 Luu-The V, Ferraris C, Duche D, Bélanger P, Leclaire J, Labrie F. Steroid metabolism and profile of steroidogenic gene expression in Episkin: high similarity with human epidermis. The Journal of Steroid Biochemistry and Molecular Biology. 107: 30-6. PMID 17662597 DOI: 10.1016/J.Jsbmb.2007.03.036  0.319
2007 Labrie F, Bélanger A, Labrie C, Candas B, Cusan L, Gomez JL. Bioavailability and metabolism of oral and percutaneous dehydroepiandrosterone in postmenopausal women. The Journal of Steroid Biochemistry and Molecular Biology. 107: 57-69. PMID 17627814 DOI: 10.1016/J.Jsbmb.2007.02.007  0.341
2007 Labrie F. Multiple intracrine hormonal targets in the prostate: opportunities and challenges. Bjui. 100: 48-51. PMID 17594360 DOI: 10.1111/J.1464-410X.2007.06955.X  0.316
2007 Faucher F, Cantin L, Pereira de Jésus-Tran K, Lemieux M, Luu-The V, Labrie F, Breton R. Mouse 17α-Hydroxysteroid Dehydrogenase (AKR1C21) Binds Steroids Differently from other Aldo-keto Reductases: Identification and Characterization of Amino Acid Residues Critical for Substrate Binding Journal of Molecular Biology. 369: 525-540. PMID 17442338 DOI: 10.1016/J.Jmb.2007.03.058  0.303
2007 Pelletier G, Li S, Luu-The V, Labrie F. Oestrogenic regulation of pro-opiomelanocortin, neuropeptide Y and corticotrophin-releasing hormone mRNAs in mouse hypothalamus. Journal of Neuroendocrinology. 19: 426-31. PMID 17388940 DOI: 10.1111/J.1365-2826.2007.01548.X  0.331
2007 Liu H, Zheng S, Bellemare V, Pelletier G, Labrie F, Luu-The V. Expression and localization of estrogenic type 12 17beta-hydroxysteroid dehydrogenase in the cynomolgus monkey. Bmc Biochemistry. 8: 2. PMID 17280614 DOI: 10.1186/1471-2091-8-2  0.313
2007 Levesque MH, El-Alfy M, Berger L, Labrie F, Labrie C. Evaluation of AIbZIP and Cdc47 as markers for human prostatic diseases. Urology. 69: 196-201. PMID 17270658 DOI: 10.1016/J.Urology.2006.11.001  0.302
2007 Pelletier G, Luu-The V, Li S, Bujold G, Labrie F. Localization and glucocorticoid regulation of 11beta-hydroxysteroid dehydrogenase type 1 mRNA in the male mouse forebrain. Neuroscience. 145: 110-5. PMID 17207581 DOI: 10.1016/J.Neuroscience.2006.11.038  0.307
2007 Takase Y, Luu-The V, Poisson-Paré D, Labrie F, Pelletier G. Expression of sulfotransferase 1E1 in human prostate as studied by in situ hybridization and immunocytochemistry. The Prostate. 67: 405-9. PMID 17187396 DOI: 10.1002/Pros.20525  0.348
2007 Labrie F, Bélanger A, Bélanger P, Bérubé R, Martel C, Cusan L, Gomez J, Candas B, Chaussade V, Castiel I, Deloche C, Leclaire J. Metabolism of DHEA in postmenopausal women following percutaneous administration. The Journal of Steroid Biochemistry and Molecular Biology. 103: 178-88. PMID 17084625 DOI: 10.1016/J.Jsbmb.2006.09.034  0.314
2007 Sancéau J, Larouche D, Caron B, Bélanger P, Coquet A, Bélanger A, Labrie F, Gauthier S. Synthesis and deuterium labelling of the pure selective estrogen receptor modulator (SERM) acolbifene glucuronides Journal of Labelled Compounds and Radiopharmaceuticals. 50: 197-206. DOI: 10.1002/Jlcr.1260  0.311
2006 Vandenput L, Labrie F, Mellström D, Swanson C, Knutsson T, Peeker R, Ljunggren Ö, Orwoll E, Eriksson AL, Damber JE, Ohlsson C. Serum levels of specific glucuronidated androgen metabolites predict BMD and prostate volume in elderly men. Journal of Bone and Mineral Research. 22: 220-227. PMID 17059374 DOI: 10.1359/Jbmr.061018  0.343
2006 Liby K, Rendi M, Suh N, Royce DB, Risingsong R, Williams CR, Lamph W, Labrie F, Krajewski S, Xu X, Kim H, Brown P, Sporn MB. The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5902-9. PMID 17020999 DOI: 10.1158/1078-0432.Ccr-06-1119  0.305
2006 Compère V, Ouellet J, Luu-The V, Dureuil B, Tonon MC, Vaudry H, Labrie F, Pelletier G. Role of androgens and glucocorticoids in the regulation of diazepam-binding inhibitor mRNA levels in male mouse hypothalamus. Brain Research. 1119: 50-7. PMID 16963002 DOI: 10.1016/J.Brainres.2006.08.046  0.335
2006 Song D, Liu G, Luu-The V, Zhao D, Wang L, Zhang H, Xueling G, Li S, Désy L, Labrie F, Pelletier G. Expression of aromatase and 17beta-hydroxysteroid dehydrogenase types 1, 7 and 12 in breast cancer. An immunocytochemical study. The Journal of Steroid Biochemistry and Molecular Biology. 101: 136-44. PMID 16930994 DOI: 10.1016/J.Jsbmb.2006.06.015  0.31
2006 Eriksson AL, Lorentzon M, Mellström D, Vandenput L, Swanson C, Andersson N, Hammond GL, Jakobsson J, Rane A, Orwoll ES, Ljunggren O, Johnell O, Labrie F, Windahl SH, Ohlsson C. SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density Journal of Clinical Endocrinology and Metabolism. 91: 5029-5037. PMID 16926255 DOI: 10.1210/Jc.2006-0679  0.315
2006 Labrie F. Dehydroepiandrosterone, androgens and the mammary gland. Gynecological Endocrinology. 22: 118-130. PMID 16835073 DOI: 10.1080/09513590600624440  0.369
2006 Labrie F, Luu-The V, Martel C, Chernomoretz A, Calvo E, Morissette J, Labrie C. Dehydroepiandrosterone (DHEA) is an anabolic steroid like dihydrotestosterone (DHT), the most potent natural androgen, and tetrahydrogestrinone (THG). The Journal of Steroid Biochemistry and Molecular Biology. 100: 52-8. PMID 16797178 DOI: 10.1016/J.Jsbmb.2006.03.006  0.365
2006 Labrie F. Future perspectives of selective estrogen receptor modulators used alone and in combination with DHEA Endocrine-Related Cancer. 13: 335-355. PMID 16728567 DOI: 10.1677/Erc.1.00883  0.347
2006 Takase Y, Lévesque MH, Luu-The V, El-Alfy M, Labrie F, Pelletier G. Expression of enzymes involved in estrogen metabolism in human prostate. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 911-21. PMID 16651392 DOI: 10.1369/Jhc.6A6927.2006  0.383
2006 Candas B, Labrie F, Gomez JL, Cusan L, Chevrette E, Lévesque J, Brousseau G. Relationship among initial serum prostate specific antigen, prostate specific antigen progression and prostate cancer detection at repeat screening visits. The Journal of Urology. 175: 510-6; discussion 51. PMID 16406983 DOI: 10.1016/S0022-5347(05)00165-5  0.3
2006 Azzi L, El-Alfy M, Labrie F. Gender differences and effects of sex steroids and dehydroepiandrosterone on androgen and oestrogen alpha receptors in mouse sebaceous glands. The British Journal of Dermatology. 154: 21-7. PMID 16403089 DOI: 10.1111/J.1365-2133.2005.06847.X  0.359
2006 Ngatcha BT, Laplante Y, Labrie F, Luu-The V, Poirier D. 3Beta-alkyl-androsterones as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase: inhibitory potency in intact cells, selectivity towards isoforms 1, 2, 5 and 7, binding affinity for steroid receptors, and proliferative/antiproliferative activities on AR+ and ER+ cell lines. Molecular and Cellular Endocrinology. 248: 225-32. PMID 16359782 DOI: 10.1016/J.Mce.2005.10.023  0.334
2005 Labrie F, Luu-The V, Bélanger A, Lin SX, Simard J, Pelletier G, Labrie C. Is dehydroepiandrosterone a hormone? The Journal of Endocrinology. 187: 169-96. PMID 16293766 DOI: 10.1677/Joe.1.06264  0.405
2005 Berger L, El-Alfy M, Martel C, Labrie F. Effects of dehydroepiandrosterone, Premarin and Acolbifene on histomorphology and sex steroid receptors in the rat vagina. The Journal of Steroid Biochemistry and Molecular Biology. 96: 201-15. PMID 15979306 DOI: 10.1016/J.Jsbmb.2005.02.018  0.369
2005 Gauthier S, Cloutier J, Dory YL, Favre A, Mailhot J, Ouellet C, Schwerdtfeger A, Mérand Y, Martel C, Simard J, Labrie F. Synthesis and structure-activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution. Journal of Enzyme Inhibition and Medicinal Chemistry. 20: 165-77. PMID 15968821 DOI: 10.1080/14756360500043448  0.337
2005 Lemieux C, Phaneuf D, Labrie F, Giguère V, Richard D, Deshaies Y. Estrogen receptor alpha-mediated adiposity-lowering and hypocholesterolemic actions of the selective estrogen receptor modulator acolbifene. International Journal of Obesity (2005). 29: 1236-44. PMID 15925950 DOI: 10.1038/Sj.Ijo.0803014  0.31
2005 Pelletier G, Luu-The V, Li S, Labrie F. Localization of type 8 17beta-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 53: 1257-71. PMID 15923359 DOI: 10.1369/Jhc.5A6692.2005  0.328
2005 Labrie F, Bélanger A, Luu-The V, Labrie C, Simard J, Cusan L, Gomez J, Candas B. Gonadotropin-releasing hormone agonists in the treatment of prostate cancer. Endocrine Reviews. 26: 361-79. PMID 15867098 DOI: 10.1210/Er.2004-0017  0.366
2005 Luu-The V, Pelletier G, Labrie F. Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase. The Journal of Steroid Biochemistry and Molecular Biology. 93: 269-76. PMID 15860270 DOI: 10.1016/J.Jsbmb.2005.01.003  0.335
2005 Pelletier G, Luu-The V, Li S, Labrie F. Localization of type 5 17β-hydroxysteroid dehydrogenase mRNA in mouse tissues as studied by in situ hybridization Cell and Tissue Research. 320: 393-398. PMID 15846505 DOI: 10.1007/S00441-005-1105-9  0.306
2005 Pelletier G, Luu-The V, Li S, Labrie F. Localization of type 7 17beta-hydroxysteroid dehydrogenase in mouse tissues. In situ hybridization studies. The Journal of Steroid Biochemistry and Molecular Biology. 93: 49-57. PMID 15748832 DOI: 10.1016/J.Jsbmb.2004.10.018  0.313
2005 Lemieux C, Gélinas Y, Lalonde J, Labrie F, Cianflone K, Deshaies Y. Hypolipidemic action of the SERM acolbifene is associated with decreased liver MTP and increased SR-BI and LDL receptors Journal of Lipid Research. 46: 1285-1294. PMID 15741653 DOI: 10.1194/Jlr.M400448-Jlr200  0.304
2005 Labrie F, Luu-The V, Calvo E, Martel C, Cloutier J, Gauthier S, Belleau P, Morissette J, Lévesque MH, Labrie C. Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid. The Journal of Endocrinology. 184: 427-33. PMID 15684350 DOI: 10.1677/Joe.1.05997  0.333
2005 Pelletier G, Luu-The V, Li S, Ren L, Labrie F. Localization of 17beta-hydroxysteroid dehydrogenase type 1 mRNA in mouse tissues. Journal of Molecular Endocrinology. 33: 459-65. PMID 15525601 DOI: 10.1677/Jme.1.01567  0.341
2004 Labrie F. Current status of endocrine therapy in localized prostate cancer: cure has become a strong possibility. International Braz J Urol. 30: 3-11. PMID 15707506 DOI: 10.1590/S1677-55382004000100002  0.332
2004 Labrie F, Cusan L, Gomez J, Luu-The V, Candas B, Bélanger A, Labrie C. Major impact of hormonal therapy in localized prostate cancer--death can already be an exception. The Journal of Steroid Biochemistry and Molecular Biology. 92: 327-44. PMID 15698538 DOI: 10.1016/J.Jsbmb.2004.10.011  0.348
2004 Labrie F. Adrenal androgens and intracrinology. Seminars in Reproductive Medicine. 22: 299-309. PMID 15635498 DOI: 10.1055/S-2004-861547  0.366
2004 Bolduc C, Larose M, Yoshioka M, Ye P, Belleau P, Labrie C, Morissette J, Raymond V, Labrie F, St-Amand J. Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression. Journal of Molecular Endocrinology. 33: 429-44. PMID 15525599 DOI: 10.1677/Jme.1.01503  0.306
2004 Pelletier G, Luu-The V, Li S, Ouellet J, Labrie F. Cellular localization of mRNA expression of enzymes involved in the formation and inactivation of hormonal steroids in the mouse prostate. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 1351-6. PMID 15385581 DOI: 10.1177/002215540405201011  0.377
2004 Dumont M, Frank D, Moisan AM, Tranchant M, Soucy P, Breton R, Labrie F, Tavtigian SV, Simard J. Structure of primate and rodent orthologs of the prostate cancer susceptibility gene ELAC2. Biochimica Et Biophysica Acta. 1679: 230-47. PMID 15358515 DOI: 10.1016/J.Bbaexp.2004.07.001  0.32
2004 Qiu W, Zhou M, Labrie F, Lin SX. Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues. Molecular Endocrinology (Baltimore, Md.). 18: 1798-807. PMID 15087468 DOI: 10.1210/Me.2004-0032  0.339
2004 Leblanc M, Bélanger MC, Julien P, Tchernof A, Labrie C, Bélanger A, Labrie F. Plasma lipoprotein profile in the male cynomolgus monkey under normal, hypogonadal, and combined androgen blockade conditions. The Journal of Clinical Endocrinology and Metabolism. 89: 1849-57. PMID 15070955 DOI: 10.1210/Jc.2003-031233  0.308
2004 Labrie F. Medical Castration With LHRH Agonists: 25 Years Later With Major Benefits Achieved on Survival in Prostate Cancer Journal of Andrology. 25: 305-313. PMID 15064303 DOI: 10.1002/J.1939-4640.2004.Tb02791.X  0.3
2004 Labrie F, Champagne P, Labrie C, Roy J, Laverdière J, Provencher L, Potvin M, Drolet Y, Pollak M, Panasci L, L'Espérance B, Dufresne J, Latreille J, Robert J, Samson B, et al. Activity and safety of the antiestrogen EM-800, the orally active precursor of acolbifene, in tamoxifen-resistant breast cancer Journal of Clinical Oncology. 22: 864-871. PMID 14990642 DOI: 10.1200/Jco.2004.05.122  0.307
2004 Pelletier G, Luu-The V, Li S, Labrie F. Localization and estrogenic regulation of androgen receptor mRNA expression in the mouse uterus and vagina. The Journal of Endocrinology. 180: 77-85. PMID 14709146 DOI: 10.1677/Joe.0.1800077  0.332
2003 Gingras S, Turgeon C, Brochu N, Soucy P, Labrie F, Simard J. Characterization and modulation of sex steroid metabolizing activity in normal human keratinocytes in primary culture and HaCaT cells. The Journal of Steroid Biochemistry and Molecular Biology. 87: 167-79. PMID 14672737 DOI: 10.1016/J.Jsbmb.2003.08.006  0.352
2003 Labrie F, Cusan L, Gomez JL, Candas B, Bélanger A, Luu-The V, Labrie C, Simard J. [From the gene to the clinic: prostate cancer death can now be an exception?]. Mã©Decine Sciences : M/S. 19: 910-9. PMID 14612999 DOI: 10.1051/Medsci/20031910910  0.351
2003 Leblanc M, Labrie C, Bélanger A, Candas B, Labrie F. Bioavailability and pharmacokinetics of dehydroepiandrosterone in the cynomolgus monkey. The Journal of Clinical Endocrinology and Metabolism. 88: 4293-302. PMID 12970301 DOI: 10.1210/Jc.2003-022012  0.384
2003 Labrie F, El-Alfy M, Berger L, Labrie C, Martel C, Bélanger A, Candas B, Pelletier G. The combination of a novel selective estrogen receptor modulator with an estrogen protects the mammary gland and uterus in a rodent model: the future of postmenopausal women's health? Endocrinology. 144: 4700-6. PMID 12960051 DOI: 10.1210/En.2003-0269  0.359
2003 Dimitrakakis C, Zhou J, Wang J, Belanger A, LaBrie F, Cheng C, Powell D, Bondy C. A physiologic role for testosterone in limiting estrogenic stimulation of the breast. Menopause (New York, N.Y.). 10: 292-8. PMID 12851512 DOI: 10.1097/01.Gme.0000055522.67459.89  0.356
2003 Pelletier G, Li S, Phaneuf D, Martel C, Labrie F. Morphological studies of prolactin-secreting cells in estrogen receptor alpha and estrogen receptor beta knockout mice. Neuroendocrinology. 77: 324-33. PMID 12806178 DOI: 10.1159/000070898  0.351
2003 Simard J, Dumont M, Labuda D, Sinnett D, Meloche C, El-Alfy M, Berger L, Lees E, Labrie F, Tavtigian SV. Prostate cancer susceptibility genes: lessons learned and challenges posed. Endocrine-Related Cancer. 10: 225-59. PMID 12790786 DOI: 10.1677/Erc.0.0100225  0.306
2003 Jensen J, Kitlen JW, Briand P, Labrie F, Lykkesfeldt AE. Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium. The Journal of Steroid Biochemistry and Molecular Biology. 84: 469-478. PMID 12732292 DOI: 10.1016/S0960-0760(03)00068-2  0.345
2003 Labrie F, Luu-The V, Labrie C, Bélanger A, Simard J, Lin SX, Pelletier G. Endocrine and intracrine sources of androgens in women: inhibition of breast cancer and other roles of androgens and their precursor dehydroepiandrosterone. Endocrine Reviews. 24: 152-82. PMID 12700178 DOI: 10.1210/Er.2001-0031  0.395
2003 Mauriège P, Martel C, Langin D, Lacaille M, Després JP, Bélanger A, Labrie F, Deshaies Y. Chronic effects of dehydroepiandrosterone on rat adipose tissue metabolism. Metabolism-Clinical and Experimental. 52: 264-272. PMID 12647261 DOI: 10.1053/Meta.2003.50043  0.342
2003 Tatchum-Talom R, Martel C, Labrie F, Marette A. Acute vascular effects of the selective estrogen receptor modulator EM-652 (SCH 57068) in the rat mesenteric vascular bed Cardiovascular Research. 57: 535-543. PMID 12566126 DOI: 10.1016/S0008-6363(02)00666-1  0.328
2002 Labrie F. Androgen blockade in prostate cancer in 2002: major benefits on survival in localized disease. Molecular and Cellular Endocrinology. 198: 77-87. PMID 12573817 DOI: 10.1016/S0303-7207(02)00371-4  0.322
2002 Leblanc M, Labrie C, Bélanger A, Candas B, Labrie F. Pharmacokinetics of oral dehydroepiandrosterone (DHEA) in the ovariectomised cynomolgus monkey. The Journal of Steroid Biochemistry and Molecular Biology. 81: 159-64. PMID 12137806 DOI: 10.1016/S0960-0760(02)00059-6  0.379
2002 Labrie F, Candas B, Gomez JL, Cusan L. Can combined androgen blockade provide long-term control or possible cure of localized prostate cancer? Urology. 60: 115-9. PMID 12100935 DOI: 10.1016/S0090-4295(02)01639-4  0.313
2002 Simoncini T, Varone G, Fornari L, Mannella P, Luisi M, Labrie F, Genazzani AR. Genomic and nongenomic mechanisms of nitric oxide synthesis induction in human endothelial cells by a fourth-generation selective estrogen receptor modulator. Endocrinology. 143: 2052-61. PMID 12021169 DOI: 10.1210/Endo.143.6.8749  0.318
2002 Simard J, Dumont M, Soucy P, Labrie F. Perspective: prostate cancer susceptibility genes. Endocrinology. 143: 2029-40. PMID 12021166 DOI: 10.1210/Endo.143.6.8890  0.309
2002 Bernardi F, Stomati M, Luisi S, Pieri M, Labrie F, Genazzani AR. Effects of the new generation selective estrogen receptor modulator EM-652 and oral administration of estradiol valerate on circulating, brain, and adrenal β-endorphin and allopregnanolone levels in intact fertile and ovariectomized rats Fertility and Sterility. 77: 1018-1027. PMID 12009361 DOI: 10.1016/S0015-0282(02)02958-8  0.365
2002 Gutman M, Couillard S, Roy J, Labrie F, Candas B, Labrie C. Comparison of the effects of EM-652 (SCH57068), tamoxifen, toremifene, droloxifene, idoxifene, GW-5638 and raloxifene on the growth of human ZR-75-1 breast tumors in nude mice. International Journal of Cancer. 99: 273-8. PMID 11979444 DOI: 10.1002/Ijc.10302  0.303
2002 Labrie F, Luu-The V, Labrie C, Pelletier G, El-Alfy M. Intracrinology and the skin. Hormone Research. 54: 218-29. PMID 11595810 DOI: 10.1159/000053264  0.365
2001 Labrie F, Labrie C, Bélanger A, Simard J, Giguère V, Tremblay A, Tremblay G. EM-652 (SCH57068), a pure SERM having complete antiestrogenic activity in the mammary gland and endometrium. The Journal of Steroid Biochemistry and Molecular Biology. 79: 213-225. PMID 11850228 DOI: 10.1016/S0960-0760(01)00139-X  0.347
2001 Pelletier G, El-Alfy M, Labrie C, Martel C, Labrie F. Effect of Long-Term Treatment with the Antiestrogen EM-652.HCl on Pituitary Estrogen Receptor Alpha and Prolactin mRNA Expression in Intact, Ovariectomized and Gonadotropin- Releasing Hormone-Treated Female Rats Neuroendocrinology. 74: 367-374. PMID 11752893 DOI: 10.1159/000054703  0.381
2001 Pelletier G, Li S, Luu-The V, Tremblay Y, Bélanger A, Labrie F. Immunoelectron microscopic localization of three key steroidogenic enzymes (cytochrome P450(scc), 3 beta-hydroxysteroid dehydrogenase and cytochrome P450(c17)) in rat adrenal cortex and gonads. The Journal of Endocrinology. 171: 373-83. PMID 11691658 DOI: 10.1677/Joe.0.1710373  0.317
2001 Pelletier G, Labrie C, Martel C, Li S, Labrie F. Role of extra-ovarian oestrogens in the regulation of gonadotropin releasing hormone mRNA expression in the rat brain. Journal of Neuroendocrinology. 13: 678-82. PMID 11489084 DOI: 10.1046/J.1365-2826.2001.00681.X  0.358
2001 Labrie F, Luu-The V, Labrie C, Simard J. DHEA and its transformation into androgens and estrogens in peripheral target tissues: intracrinology. Frontiers in Neuroendocrinology. 22: 185-212. PMID 11456468 DOI: 10.1006/Frne.2001.0216  0.407
2001 Labrie F, Labrie C, Bélanger A, Giguere V, Simard J, Mérand Y, Gauthier S, Luu-The V, Candas B, Martel C, Luo S. Pure selective estrogen receptor modulators, new molecules having absolute cell specificity ranging from pure antiestrogenic to complete estrogen-like activities. Advances in Protein Chemistry. 56: 293-368. PMID 11329857 DOI: 10.1016/S0065-3233(01)56009-X  0.344
2001 Barbier O, Albert C, Martineau I, Vallée M, High K, Labrie F, Hum DW, Labrie C, Bélanger A. Glucuronidation of the nonsteroidal antiestrogen EM-652 (SCH 57068), by human and monkey steroid conjugating UDP-glucuronosyltransferase enzymes. Molecular Pharmacology. 59: 636-45. PMID 11179460 DOI: 10.1124/Mol.59.3.636  0.3
2001 Pelletier G, Luu-The V, El-Alfy M, Li S, Labrie F. Immunoelectron microscopic localization of 3beta-hydroxysteroid dehydrogenase and type 5 17beta-hydroxysteroid dehydrogenase in the human prostate and mammary gland. Journal of Molecular Endocrinology. 26: 11-9. PMID 11174850 DOI: 10.1677/Jme.0.0260011  0.332
2001 Luu-The V, Dufort I, Pelletier G, Labrie F. Type 5 17beta-hydroxysteroid dehydrogenase: its role in the formation of androgens in women. Molecular and Cellular Endocrinology. 171: 77-82. PMID 11165014 DOI: 10.1016/S0303-7207(00)00425-1  0.329
2001 Labrie F, Luu-The V, Lin SX, Simard J, Labrie C. Role of 17 beta-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues. Trends in Endocrinology and Metabolism: Tem. 11: 421-7. PMID 11091120 DOI: 10.1016/S1043-2760(00)00342-8  0.339
2001 Sourla A, Richard V, Labrie F, Labrie C. Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin. The Journal of Endocrinology. 166: 455-62. PMID 10927635 DOI: 10.1677/Joe.0.1660455  0.344
2000 Singh R, Eeles RA, Durocher F, Simard J, Edwards S, Badzioch M, Kote-Jarai Z, Teare D, Ford D, Dearnaley D, Ardern-Jones A, Murkin A, Dowe A, Shearer R, Kelly J, ... Labrie F, et al. High risk genes predisposing to prostate cancer development-do they exist? Prostate Cancer and Prostatic Diseases. 3: 241-247. PMID 12497071 DOI: 10.1038/Sj.Pcan.4500478  0.305
2000 Boivin RP, Luu-The V, Lachance R, Labrie F, Poirier D. Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase. Journal of Medicinal Chemistry. 43: 4465-78. PMID 11087571 DOI: 10.1021/Jm0001166  0.329
2000 El-Alfy M, Pelletier G, Hermo LS, Labrie F. Unique features of the basal cells of human prostate epithelium. Microscopy Research and Technique. 51: 436-446. PMID 11074614 DOI: 10.1002/1097-0029(20001201)51:5<436::Aid-Jemt6>3.0.Co;2-T  0.32
2000 Martel C, Picard S, Richard V, Bélanger A, Labrie C, Labrie F. Prevention of bone loss by EM-800 and raloxifene in the ovariectomized rat. The Journal of Steroid Biochemistry and Molecular Biology. 74: 45-56. PMID 11074355 DOI: 10.1016/S0960-0760(00)00087-X  0.302
2000 Labrie F, Candas B. Androgen blockade in prostate cancer The Lancet. 356: 341-342. PMID 11071217 DOI: 10.1016/S0140-6736(05)73625-4  0.333
2000 Candas B, Cusan L, Gomez JL, Diamond P, Suburu RE, Lévesque J, Brousseau G, Bélanger A, Labrie F. Evaluation of prostatic specific antigen and digital rectal examination as screening tests for prostate cancer. The Prostate. 45: 19-35. PMID 10960839 DOI: 10.1002/1097-0045(20000915)45:1<19::Aid-Pros3>3.0.Co;2-M  0.316
2000 Picard F, Deshaies Y, Lalonde J, Samson P, Labrie C, Bélanger A, Labrie F, Richard D. Effects of the estrogen antagonist EM-652.HCl on energy balance and lipid metabolism in ovariectomized rats International Journal of Obesity. 24: 830-840. PMID 10918529 DOI: 10.1038/Sj.Ijo.0801240  0.333
2000 Labrie F, Luu-The V, Lin SX, Simard J, Labrie C, El-Alfy M, Pelletier G, Bélanger A. Intracrinology: role of the family of 17 beta-hydroxysteroid dehydrogenases in human physiology and disease. Journal of Molecular Endocrinology. 25: 1-16. PMID 10915214 DOI: 10.1677/Jme.0.0250001  0.342
2000 Pelletier C, Labrie C, Labrie F. Localization of oestrogen receptor α, oestrogen receptor β and androgen receptors in the rat reproductive organs Journal of Endocrinology. 165: 359-370. PMID 10810300 DOI: 10.1677/Joe.0.1650359  0.368
2000 Labrie F. Screening and early hormonal treatment of prostate cancer are accumulating strong evidence and support. The Prostate. 43: 215-222. PMID 10797496 DOI: 10.1002/(Sici)1097-0045(20000515)43:3<215::Aid-Pros7>3.0.Co;2-G  0.328
2000 Couillard S, Labrie C, Gauthier S, Merand Y, Singh SM, Candas B, Labrie F. Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice. International Journal of Cancer. 85: 424-9. PMID 10652436 DOI: 10.1002/(Sici)1097-0215(20000201)85:3<424::Aid-Ijc20>3.0.Co;2-S  0.302
2000 Singh SM, Gauthier S, Labrie F. Androgen Receptor Antagonists (Antiandrogens) Structure-Activity Relationships Current Medicinal Chemistry. 7: 211-247. PMID 10637363 DOI: 10.2174/0929867003375371  0.383
2000 Zhu DW, Campbell R, Labrie F, Lin SX. Crystallization and preliminary crystal structure of the complex of 17beta-hydroxysteroid dehydrogenase with a dual-site inhibitor. The Journal of Steroid Biochemistry and Molecular Biology. 70: 229-35. PMID 10622412 DOI: 10.1016/S0960-0760(99)00111-9  0.308
1999 Kwast THVd, Labrie F, Têtu B. Persistence of high-grade prostatic intra-epithelial neoplasia under combined androgen blockade therapy Human Pathology. 30: 1503-1507. PMID 10667430 DOI: 10.1016/S0046-8177(99)90174-0  0.324
1999 Hida N, Poulin R, Veilleux R, Labrie F. Differential androgen sensitivity is associated with clonal heterogeneity in steroid metabolism, ornithine decarboxylase regulation and IL-1α action in mouse mammary tumor cells The Journal of Steroid Biochemistry and Molecular Biology. 71: 71-81. PMID 10619359 DOI: 10.1016/S0960-0760(99)00120-X  0.323
1999 Boivin RP, Labrie F, Poirier D. 17α-Alkan (or alkyn) amide derivatives of estradiol as inhibitors of steroid-sulfatase activity Steroids. 64: 825-833. PMID 10576217 DOI: 10.1016/S0039-128X(99)00060-4  0.316
1999 Pelletier G, Luu-The V, Charbonneau A, Labrie F. Cellular localization of estrogen receptor beta messenger ribonucleic acid in cynomolgus monkey reproductive organs Biology of Reproduction. 61: 1249-1255. PMID 10529271 DOI: 10.1095/Biolreprod61.5.1249  0.36
1999 Tremblay MR, Luu-The V, Leblanc G, Noël P, Breton E, Labrie F, Poirier D. Spironolactone-related inhibitors of type II 17beta-hydroxysteroid dehydrogenase: chemical synthesis, receptor binding affinities, and proliferative/antiproliferative activities. Bioorganic & Medicinal Chemistry. 7: 1013-23. PMID 10428369 DOI: 10.1016/S0968-0896(98)00260-0  0.33
1999 Labrie F, Labrie C, Bélanger A, Simard J, Gauthier S, Luu-The V, Mérand Y, Giguere V, Candas B, Luo S, Martel C, Singh SM, Fournier M, Coquet A, Richard V, et al. EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium. The Journal of Steroid Biochemistry and Molecular Biology. 69: 51-84. PMID 10418981 DOI: 10.1016/S0960-0760(99)00065-5  0.377
1999 Ciobanu LC, Boivin RP, Luu-The V, Labrie F, Poirier D. Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol. Journal of Medicinal Chemistry. 42: 2280-6. PMID 10377235 DOI: 10.1021/Jm980677L  0.336
1999 Pelletier G, Luu-The V, Têtu B, Labrie F. Immunocytochemical localization of type 5 17beta-hydroxysteroid dehydrogenase in human reproductive tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 47: 731-8. PMID 10330449 DOI: 10.1177/002215549904700602  0.344
1999 Kwast THvd, Labrie F, Têtu B. Prostatic intraepithelial neoplasia and endocrine manipulation. European Urology. 35: 508-510. PMID 10325515 DOI: 10.1159/000019889  0.314
1999 van der Kwast TH, Têtu B, Candas B, Gomez JL, Cusan L, Labrie F. Prolonged neoadjuvant combined androgen blockade leads to a further reduction of prostatic tumor volume: three versus six months of endocrine therapy. Urology. 53: 523-9. PMID 10096378 DOI: 10.1016/S0090-4295(98)00542-1  0.306
1999 El-Alfy M, Luu-The V, Huang XF, Berger L, Labrie F, Pelletier G. Localization of type 5 17beta-hydroxysteroid dehydrogenase, 3beta-hydroxysteroid dehydrogenase, and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology. 140: 1481-91. PMID 10067877 DOI: 10.1210/Endo.140.3.6585  0.363
1999 Tremblay GB, Tremblay A, Labrie F, Giguère V. Dominant activity of activation function 1 (AF-1) and differential stoichiometric requirements for AF-1 and -2 in the estrogen receptor α-β heterodimeric complex Molecular and Cellular Biology. 19: 1919-1927. PMID 10022879 DOI: 10.1128/Mcb.19.3.1919  0.302
1999 Labrie F, Candas B, Dupont A, Cusan L, Gomez JL, Suburu RE, Diamond P, Lévesque J, Belanger A. Screening decreases prostate cancer death: first analysis of the 1988 Quebec prospective randomized controlled trial. The Prostate. 38: 83-91. PMID 9973093 DOI: 10.1002/(Sici)1097-0045(19990201)38:2<83::Aid-Pros1>3.0.Co;2-B  0.303
1999 Labrie F, Cusan L, Gomez J, Levesque J, Candas B. Screening and treatment of localized prostate cancer decreases mortality: First analysis of the first prospective and randomized study on prostate cancer screening The Aging Male. 2: 33-43. DOI: 10.3109/13685539909003181  0.306
1999 Labrie F, Candas B. The Quebec study shows a 69% decrease in prostate cancer death The Prostate. 40: 137-137. DOI: 10.1002/(Sici)1097-0045(19990701)40:2<137::Aid-Pros12>3.0.Co;2-P  0.302
1998 Martel CL, Labrie C, Be Langer A, Gauthier S, Me Rand Y, Li X, Provencher L, Candas B, Labrie F. Comparison of the Effects of the New Orally Active Antiestrogen EM-800 with ICI 182 780 and Toremifene on Estrogen-Sensitive Parameters in the Ovariectomized Mouse. Endocrinology. 139: 2486-2492. PMID 28200575 DOI: 10.1210/Endo.139.5.5968  0.342
1998 Tremblay A, Tremblay GB, Labrie C, Labrie F, Gigue Re V. EM-800, a Novel Antiestrogen, Acts as a Pure Antagonist of the Transcriptional Functions of Estrogen Receptors α and β. Endocrinology. 139: 111-118. PMID 28200444 DOI: 10.1210/Endo.139.1.5702  0.348
1998 Kwast THVD, Têtu B, Suburu ER, Gomez J, Lemay M, Labrie F. Cycling activity of benign prostatic epithelial cells during long-term androgen blockade: evidence for self-renewal of luminal cells. The Journal of Pathology. 186: 406-409. PMID 10209490 DOI: 10.1002/(Sici)1096-9896(199812)186:4<406::Aid-Path205>3.0.Co;2-L  0.329
1998 Sourla A, Flamand M, Bélanger A, Labrie F. Effect of dehydroepiandrosterone on vaginal and uterine histomorphology in the rat. The Journal of Steroid Biochemistry and Molecular Biology. 66: 137-49. PMID 9719448 DOI: 10.1016/S0960-0760(98)00052-1  0.362
1998 Turgeon C, Gingras S, Carrière MC, Blais Y, Labrie F, Simard J. Regulation of sex steroid formation by interleukin-4 and interleukin-6 in breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 65: 151-62. PMID 9699868 DOI: 10.1016/S0960-0760(98)00031-4  0.302
1998 Martel C, Sourla A, Pelletier G, Labrie C, Fournier M, Picard S, Li S, Stojanovic M, Labrie F. Predominant androgenic component in the stimulatory effect of dehydroepiandrosterone on bone mineral density in the rat. The Journal of Endocrinology. 157: 433-42. PMID 9691976 DOI: 10.1677/Joe.0.1570433  0.313
1998 Labrie F, Bélanger A, Luu-The V, Labrie C, Simard J, Cusan L, Gomez JL, Candas B. DHEA and the intracrine formation of androgens and estrogens in peripheral target tissues: its role during aging. Steroids. 63: 322-8. PMID 9618795 DOI: 10.1016/S0039-128X(98)00007-5  0.364
1998 Martel C, Provencher L, Li X, Pierre AS, Leblanc G, Gauthier S, Mérand Y, Labrie F. Binding Characteristics of Novel Nonsteroidal Antiestrogens to the Rat Uterine Estrogen Receptors The Journal of Steroid Biochemistry and Molecular Biology. 64: 199-205. PMID 9605415 DOI: 10.1016/S0960-0760(97)00192-1  0.369
1998 Luo S, Sourla A, Labrie C, Gauthier S, Merand Y, Belanger A, Labrie F. Effect of twenty-four-week treatment with the antiestrogen EM-800 on estrogen-sensitive parameters in intact and ovariectomized mice. Endocrinology. 139: 2645-56. PMID 9564882 DOI: 10.1210/Endo.139.5.5994  0.35
1998 Sourla A, Martel C, Labrie C, Labrie F. Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland Endocrinology. 139: 753-764. PMID 9449650 DOI: 10.1210/Endo.139.2.5762  0.406
1998 Luo S, Martel C, Chen C, Labrie C, Candas B, Singh SM, Labrie F. Daily dosing with flutamide or Casodex exerts maximal antiandrogenic activity. Urology. 50: 913-9. PMID 9426723 DOI: 10.1016/S0090-4295(97)00393-2  0.342
1998 PELLETIER G, LUU-THE V, HUANG X, LAPOINTE H, LABRIE F. LOCALIZATION BY IN SITU HYBRIDIZATION OF STEROID 5 alpha-REDUCTASE ISOZYME GENE EXPRESSION IN THE HUMAN PROSTATE AND PREPUTIAL SKIN Journal of Urology. 160: 577-582. DOI: 10.1016/S0022-5347(01)62961-6  0.321
1997 Sourla A, Luo S, Labrie C, Be Langer A, Labrie F. Morphological Changes Induced by 6-Month Treatment of Intact and Ovariectomized Mice with Tamoxifen and the Pure Antiestrogen EM-800. Endocrinology. 138: 5605-5617. PMID 28200117 DOI: 10.1210/Endo.138.12.5560  0.369
1997 Luo S, Martel C, Gauthier S, Mérand Y, Bélanger A, Labrie C, Labrie F. Long-term inhibitory effects of a novel anti-estrogen on the growth of ZR-75-1 and MCF-7 human breast cancer tumors in nude mice. International Journal of Cancer. 73: 735-9. PMID 9398055 DOI: 10.1002/(Sici)1097-0215(19971127)73:5<735::Aid-Ijc21>3.0.Co;2-3  0.326
1997 Luo S, Stojanovic M, Labrie C, Labrie F. Inhibitory effect of the novel anti-estrogen EM-800 and medroxyprogesterone acetate on estrone-stimulated growth of dimethylbenz[a]anthracene-induced mammary carcinoma in rats. International Journal of Cancer. 73: 580-6. PMID 9389575 DOI: 10.1002/(Sici)1097-0215(19971114)73:4<580::Aid-Ijc20>3.0.Co;2-C  0.327
1997 Luo S, Martel C, Sourla A, Gauthier S, Mérand Y, Belanger A, Labrie C, Labrie F. Comparative effects of 28-day treatment with the new anti-estrogen EM-800 and tamoxifen on estrogen-sensitive parameters in intact mice. International Journal of Cancer. 73: 381-91. PMID 9359486 DOI: 10.1002/(Sici)1097-0215(19971104)73:3<381::Aid-Ijc13>3.0.Co;2-G  0.38
1997 Simard J, Labrie C, Bélanger A, Gauthier S, Singh SM, Mérand Y, Labrie F. Characterization of the effects of the novel non-steroidal antiestrogen EM-800 on basal and estrogen-induced proliferation of T-47D, ZR-75-1 and MCF-7 human breast cancer cells in vitro. International Journal of Cancer. 73: 104-12. PMID 9334816 DOI: 10.1002/(Sici)1097-0215(19970926)73:1<104::Aid-Ijc16>3.0.Co;2-G  0.34
1997 Tchernof A, Labrie F, Bélanger A, Prud'homme D, Bouchard C, Tremblay A, Nadeau A, Després JP. Relationships between endogenous steroid hormone, sex hormone-binding globulin and lipoprotein levels in men: contribution of visceral obesity, insulin levels and other metabolic variables. Atherosclerosis. 133: 235-44. PMID 9298684 DOI: 10.1016/S0021-9150(97)00125-1  0.311
1997 Durocher F, Simard J, Ouellette J, Richard V, Labrie F, Pelletier G. Localization of BRCA1 Gene Expression in Adult Cynomolgus Monkey Tissues Journal of Histochemistry and Cytochemistry. 45: 1173-1188. PMID 9283605 DOI: 10.1177/002215549704500901  0.305
1997 Labrie F, Bélanger A, Cusan L, Candas B. Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology. The Journal of Clinical Endocrinology and Metabolism. 82: 2403-9. PMID 9253308 DOI: 10.1210/Jcem.82.8.4161  0.395
1997 Labrie F, Cusan L, Gomez JL, Diamond P, Suburu R, Lemay M, Tetu B, Fradet Y, Bélanger A, Candas B. Neoadjuvant hormonal therapy: the Canadian experience. Urology. 49: 56-64. PMID 9123738 DOI: 10.1016/S0090-4295(97)00170-2  0.332
1997 Simard J, Singh SM, Labrie F. Comparison of in vitro effects of the pure antiandrogens OH-flutamide, casodex, and nilutamide on androgen-sensitive parameters☆ Urology. 49: 580-589. PMID 9111629 DOI: 10.1016/S0090-4295(97)00029-0  0.392
1997 Tremblay GB, Tremblay A, Copeland NG, Gilbert DJ, Jenkins NA, Labrie F, Giguère V. Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta. Molecular Endocrinology (Baltimore, Md.). 11: 353-65. PMID 9058381 DOI: 10.1210/Mend.11.3.9902  0.335
1997 Labrie F, Luu-The V, Lin SX, Labrie C, Simard J, Breton R, Bélanger A. The key role of 17 beta-hydroxysteroid dehydrogenases in sex steroid biology. Steroids. 62: 148-58. PMID 9029730 DOI: 10.1016/S0039-128X(96)00174-2  0.305
1997 Poulin M, Simard J, Catford J, Labrie F, Piché Y. Response of Symbiotic Endomycorrhizal Fungi to Estrogens and Antiestrogens Molecular Plant-Microbe Interactions. 10: 481-487. DOI: 10.1094/Mpmi.1997.10.4.481  0.331
1996 Chen C, Poulin R, Labrie F. Large Shionogi tumors lose their responsiveness to flutamide treatment The Journal of Steroid Biochemistry and Molecular Biology. 58: 489-494. PMID 8918974 DOI: 10.1016/0960-0760(96)00069-6  0.307
1996 Pelletier G, Luu-The V, Labrie F. Immunocytochemical localization of type I 17 beta-hydroxysteroid dehydrogenase in the rat brain. Brain Research. 704: 233-39. PMID 8788919 DOI: 10.1016/0006-8993(95)01119-6  0.311
1996 Azzi A, Rehse PH, Zhu DW, Campbell RL, Labrie F, Lin SX. Crystal structure of human estrogenic 17 beta-hydroxysteroid dehydrogenase complexed with 17 beta-estradiol. Nature Structural Biology. 3: 665-8. PMID 8756321 DOI: 10.1038/Nsb0896-665  0.318
1996 Puy LA, Turgeon C, Gagné D, Labrie Y, Chen C, Pelletier G, Simard J, Labrie F. Localization and regulation of expression of the FAR-17A gene in the hamster flank organs. The Journal of Investigative Dermatology. 107: 44-50. PMID 8752838 DOI: 10.1111/1523-1747.Ep12297867  0.701
1996 Chen C, Belanger A, Labrie F. Adrenal steroid precursors exert potent androgenic action in the hamster sebaceous glands of flank organs and ears. Endocrinology. 137: 1752-7. PMID 8612511 DOI: 10.1210/Endo.137.5.8612511  0.338
1996 Labrie F, Candas B, Cusan L, Gomez JL, Diamond P, Suburu R, Lemay M. Diagnosis of advanced or noncurable prostate cancer can be practically eliminated by prostate-specific antigen. Urology. 47: 212-7. PMID 8607237 DOI: 10.1016/S0090-4295(99)80419-1  0.304
1996 Van der Kwast TH, Têtu B, Fradet Y, Dupont A, Gomez J, Cusan L, Diamond P, Labrie F. Androgen receptor modulation in benign human prostatic tissue and prostatic adenocarcinoma during neoadjuvant endocrine combination therapy. The Prostate. 28: 227-31. PMID 8602398 DOI: 10.1002/(Sici)1097-0045(199604)28:4<227::Aid-Pros3>3.0.Co;2-A  0.348
1996 Lopez-Solache I, Luu-The V, Sŕalini G, Labrie F. Heterogeneity of rat type I 5α-reductase cDNA: cloning, expression and regulation by pituitary implants and dihydrotestosterone Biochimica Et Biophysica Acta. 1305: 139-144. PMID 8597599 DOI: 10.1016/0167-4781(95)00198-0  0.317
1996 Vailancourt L, Ttu B, Fradet Y, Dupont A, Gomez J, Cusan L, Suburu ER, Diamond P, Candas B, Labrie F. Effect of neoadjuvant endocrine therapy (combined androgen blockade) on normal prostate and prostatic carcinoma. A randomized study. The American Journal of Surgical Pathology. 20: 86-93. PMID 8540613 DOI: 10.1097/00000478-199601000-00010  0.33
1996 Labrie C, Flamand M, Bélanger A, Labrie F. High bioavailability of dehydroepiandrosterone administered percutaneously in the rat. Journal of Endocrinology. 150. DOI: 10.1677/Joe.0.150S107  0.381
1996 Labrie F, Belanger A, Cusan L, Labrie C, Simard J, Luu-The V, Diamond P, Gomez J, Candas B. History of LHRH agonist and combination therapy in prostate cancer Endocrine Related Cancer. 3: 243-278. DOI: 10.1677/Erc.0.0030243  0.321
1995 Han X, Rossdale PD, Ousey J, Holdstock N, Allen WR, Silver M, Fowden AL, McGLADDERY AJ, Labrie F, Belanger A, Ensor CM, Tai H, Challis JRG. Localisation of 15‐hydroxy prostaglandin dehydrogenase (PGDH) and steroidogenic enzymes in the equine placenta Equine Veterinary Journal. 27: 334-339. PMID 8654347 DOI: 10.1111/J.2042-3306.1995.Tb04067.X  0.31
1995 Labrie F, Bélanger A, Simard J, Van Luu-The, Labrie C. DHEA and peripheral androgen and estrogen formation: intracinology. Annals of the New York Academy of Sciences. 774: 16-28. PMID 8597456 DOI: 10.1111/J.1749-6632.1995.Tb17369.X  0.349
1995 Labrie F, Li S, Labrie C, Lévesque C, Mérand Y. Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat Breast Cancer Research and Treatment. 33: 237-244. PMID 7749151 DOI: 10.1007/Bf00665948  0.338
1995 Li X, Singh SM, Cote J, Laplante S, Veilleux R, Labrie F. Synthesis and in vitro evaluation of 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17 beta-carboxamides as 5 alpha-reductase inhibitors and antiandrogens. Journal of Medicinal Chemistry. 38: 1456-1461. PMID 7739004 DOI: 10.1021/Jm00009A006  0.316
1995 Ghosh D, Pletnev VZ, Zhu DW, Wawrzak Z, Duax WL, Pangborn W, Labrie F, Lin SX. Structure of human estrogenic 17β-hydroxysteroid dehydrogenase at 2.20 å resolution Structure. 3: 503-513. PMID 7663947 DOI: 10.1016/S0969-2126(01)00183-6  0.303
1995 Valle LD, Couët J, Labrie Y, Simard J, Belvedere P, Simontacchi C, Labrie F, Colombo L. Occurrence of cytochrome P450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract Molecular and Cellular Endocrinology. 111: 83-92. PMID 7649357 DOI: 10.1016/0303-7207(95)03553-J  0.317
1995 Li S, Lévesque C, Geng C, Yan X, Labrie F. Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Research and Treatment. 34: 147-159. PMID 7647332 DOI: 10.1007/Bf00665787  0.311
1995 Ghosh D, Wawrzak Z, Pletnev V, Erman M, Duax WL, Pangborn W, Zhu DW, Labrie F, Lin SX. Molecular mechanism of inhibition of steroid dehydrogenases by licorice-derived steroid analogs in modulation of steroid receptor function Annals of the New York Academy of Sciences. 761: 341-343. PMID 7625731 DOI: 10.1111/J.1749-6632.1995.Tb31388.X  0.306
1995 Chen C, Puy LA, Simard J, Li X, Singh SM, Labrie F. Local and Systemic Reduction by Topical Finasteride or Flutamide of Hamster Flank Organ Size and Enzyme Activity Journal of Investigative Dermatology. 105: 678-682. PMID 7594643 DOI: 10.1111/1523-1747.Ep12324390  0.343
1995 Sun S, Narod SA, Aprikian A, Ghadirian P, Labrie F. Androgen receptor and familial prostate cancer. Nature Medicine. 1: 848-9. PMID 7585194 DOI: 10.1038/Nm0995-848B  0.318
1995 Labrie F, Cusan L, Gomez JL, Diamond P, Candas B. Combination of screening and preoperative endocrine therapy: the potential for an important decrease in prostate cancer mortality. The Journal of Clinical Endocrinology and Metabolism. 80: 2002-13. PMID 7541800 DOI: 10.1210/Jcem.80.7.7541800  0.317
1995 Labrie F, Crawford D, Quartey P, Dalesio O, Peto R, Schröder F, Waxman J, Pandha H. Anti-androgens in treatment of prostate cancer. The Lancet. 346: 1030-1031. DOI: 10.1016/S0140-6736(95)91710-1  0.317
1994 Labrie F, Li S, Bélanger A, Côté J, Mérand Y, Lepage M. Controlled release low dose medroxyprogesterone acetate (MPA) inhibits the development of mammary tumors induced by dimethyl-benz(a) anthracene in the rat. Breast Cancer Research and Treatment. 26: 253-65. PMID 8251650 DOI: 10.1007/Bf00665803  0.309
1994 Martel C, Gagné D, Couet J, Labrie Y, Simard J, Labrie F. Rapid modulation of ovarian 3β-hydroxysteroid dehydrogenase/Δ5-Δ4 isomerase gene expression by prolactin and human chorionic gonadotropin in the hypophysectomized rat Molecular and Cellular Endocrinology. 99: 63-71. PMID 8187962 DOI: 10.1016/0303-7207(94)90147-3  0.726
1994 Bernier F, Lopez Solache I, Labrie F, Luu-The V. Cloning and expression of cDNA encoding human placental estrogen sulfotransferase. Molecular and Cellular Endocrinology. 99: R11-5. PMID 8187949 DOI: 10.1016/0303-7207(94)90159-7  0.312
1994 Poirier D, Auger S, Merand Y, Simard J, Labrie F. Synthesis and Antiestrogenic Activity of Diaryl Thioether Derivatives Journal of Medicinal Chemistry. 37: 1115-1125. PMID 8164253 DOI: 10.1021/Jm00034A009  0.304
1994 Labrie Y, Couët J, Simard J, Labrie F. Multihormonal regulation of dehydroepiandrosterone sulfotransferase messenger ribonucleic acid levels in adult rat liver Endocrinology. 134: 1693-1699. PMID 8137732 DOI: 10.1210/Endo.134.4.8137732  0.341
1994 Li S, Martel C, Dauvois S, Bélanger A, Labrie F. Effect of estrone on the growth of 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in the rat: a model of postmenopausal breast cancer. Endocrinology. 134: 1352-7. PMID 8119175 DOI: 10.1210/Endo.134.3.8119175  0.33
1994 Young J, Couzinet B, Pholsena M, Nahoul K, Labrie F, Schaison G. Plasma 3 beta-hydroxy-delta 5-steroids in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency The Journal of Clinical Endocrinology and Metabolism. 78: 299-304. PMID 8106615 DOI: 10.1210/Jcem.78.2.8106615  0.318
1994 Labrie F, Simard J, Luu-The V, Pelletier G, Belghmi K, Bélanger A. Structure, regulation and role of 3 beta-hydroxysteroid dehydrogenase, 17 beta-hydroxysteroid dehydrogenase and aromatase enzymes in the formation of sex steroids in classical and peripheral intracrine tissues. Bailliere's Clinical Endocrinology and Metabolism. 8: 451-74. PMID 8092980 DOI: 10.1016/S0950-351X(05)80261-7  0.323
1994 Dupont E, Simard J, Luu-The V, Labrie F, Pelletier G. Localization of 3 beta-hydroxysteroid dehydrogenase in rat brain as studied by in situ hybridization. Molecular and Cellular Neurosciences. 5: 119-23. PMID 8032681 DOI: 10.1006/Mcne.1994.1014  0.301
1994 Couet J, Martel C, Labrie Y, Luo S, Simard J, Labrie F. Opposite effects of prolactin and corticosterone on the expression and activity of 3β-hydroxysteroid dehydrogenase/δ5-δ4 isomerase in rat skin Journal of Investigative Dermatology. 103: 60-64. PMID 8027581 DOI: 10.1111/1523-1747.Ep12389663  0.323
1994 Bélanger A, Candas B, Dupont A, Cusan L, Diamond P, Gomez JL, Labrie F. Changes in serum concentrations of conjugated and unconjugated steroids in 40- to 80-year-old men. The Journal of Clinical Endocrinology and Metabolism. 79: 1086-90. PMID 7962278 DOI: 10.1210/Jcem.79.4.7962278  0.338
1994 Sanchez R, de Launoit Y, Durocher F, Bélanger A, Labrie F, Simard J. Formation and degradation of dihydrotestosterone by recombinant members of the rat 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase family. Molecular and Cellular Endocrinology. 103: 29-38. PMID 7958395 DOI: 10.1016/0303-7207(94)90066-3  0.301
1994 Breton R, Yang F, Jin JZ, Li B, Labrie F, Lin SX. Human 17 beta-hydroxysteroid dehydrogenase: overproduction using a baculovirus expression system and characterization. The Journal of Steroid Biochemistry and Molecular Biology. 50: 275-82. PMID 7918113 DOI: 10.1016/0960-0760(94)90132-5  0.306
1994 Pelletier JD, Labrie F, Poirier D. N-butyl, N-methyl, 11-[3′,17′ β-(dihydroxy)-1′,3′,5′(10′)- estratrien-16′ α-yl]-9(R/S)-bromo undecanamide: synthesis and 17β-HSD inhibiting, estrogenic and antiestrogenic activities Steroids. 59: 536-547. PMID 7846736 DOI: 10.1016/0039-128X(94)90072-8  0.318
1994 Martel C, Meiner MH, Gagné D, Simarda J, Labrie F. Widespread tissue distribution of steroid sulfatase, 3β-hydroxysteroid dehydrogenase/Δ5-Δ4isomerase(3β-HSD), 17β-HSD5α-reductase and aromatase activities in the rhesus monkey Molecular and Cellular Endocrinology. 104: 103-111. PMID 7821701 DOI: 10.1016/0303-7207(94)90056-6  0.713
1994 Sugimoto K, Simard J, Haagensen DE, Labrie F. Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells The Journal of Steroid Biochemistry and Molecular Biology. 51: 167-174. PMID 7526888 DOI: 10.1016/0960-0760(94)90090-6  0.325
1994 Cusan L, Gomez JL, Dupont A, Diamond P, Lemay M, Moore S, Labrie F. Metastatic prostate cancer pulmonary nodules: beneficial effects of combination therapy and subsequent withdrawal of flutamide. The Prostate. 24: 257-61. PMID 7513417 DOI: 10.1002/Pros.2990240507  0.317
1994 Labrie F, Cusan L, Gomez J, Diamond P, Suburu R, Lemay M, Tetu B, Fradet Y, Candas B. Down-staging of early stage prostate cancer before radical prostatectomy: The first randomized trial of neoadjuvant combination therapy with flutamide and a luteinizing hormone-releasing hormone agonist Urology. 44: 29-37. DOI: 10.1016/S0090-4295(94)80241-6  0.321
1993 Dupont A, Cusan L, Gomez JL, Koutsilieris M, Suburu R, Emond J, Labrie F. Combination therapy with flutamide and the LHRH agonist [D-Trp6, des-Gly-NH(2)10]LHRH ethylamide in stage C prostatic carcinoma. British Journal of Urology. 72: 629-34. PMID 10071551 DOI: 10.1111/J.1464-410X.1993.Tb16223.X  0.31
1993 Martel C, Trudel C, Couet J, Labrie C, Bélanger A, Labrie F. Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA. Molecular and Cellular Endocrinology. 91: 43-9. PMID 8472853 DOI: 10.1016/0303-7207(93)90253-G  0.401
1993 Li S, Lepage M, Mérand Y, Bélanger A, Labrie F. Growth inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary tumors by controlled-release low-dose medroxyprogesterone acetate. Breast Cancer Research and Treatment. 24: 127-37. PMID 8443400 DOI: 10.1007/Bf01961245  0.329
1993 Juneau C, Dupont E, Luu-The V, Labrie F, Pelletier G. Ontogenesis of 3β-hydroxysteroid dehydrogenase Δ5-Δ4 isomerase in the rat ovary as studied by immunocytochemistry and in situ hybridization Biology of Reproduction. 48: 226-234. PMID 8439611 DOI: 10.1095/Biolreprod48.2.226  0.32
1993 Labrie F, Belanger A, Simard J, Labrie C, Dupont A. Combination therapy for prostate cancer. Endocrine and biologic basis of its choice as new standard first-line therapy. Cancer. 71: 1059-67. PMID 8428328 DOI: 10.1002/1097-0142(19930201)71:3+<1059::Aid-Cncr2820711426>3.0.Co;2-6  0.365
1993 Couture P, Thériault C, Simard J, Labrie F. Androgen receptor-mediated stimulation of 17 beta-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Endocrinology. 132: 179-85. PMID 8380373 DOI: 10.1210/Endo.132.1.8380373  0.34
1993 Labrie F. Mechanism of action and pure antiandrogenic properties of flutamide Cancer. 72: 3816-3827. PMID 8252497 DOI: 10.1002/1097-0142(19931215)72:12+<3816::Aid-Cncr2820721711>3.0.Co;2-3  0.407
1993 Dupont E, Labrie F, Luu-The V, Pelletier G. Ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) in rat testis as studied by immunocytochemistry. Anatomy and Embryology. 187: 583-9. PMID 8214615 DOI: 10.1007/Bf00214437  0.331
1993 Dupont A, Gomez JL, Cusan L, Koutsilieris M, Labrie F. Response to flutamide withdrawal in advanced prostate cancer in progression under combination therapy. The Journal of Urology. 150: 908-13. PMID 7688437 DOI: 10.1016/S0022-5347(17)35646-X  0.363
1992 Dupont E, Labrie F, Luu-The V, Pelletier G. Immunocytochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human ovary. The Journal of Clinical Endocrinology and Metabolism. 74: 994-8. PMID 1569177 DOI: 10.1210/Jcem.74.5.1569177  0.336
1992 Roy R, Dauvois S, Labrie F, Belanger A. Estrogen-stimulated glucuronidation of dihydrotestosterone in MCF-7 human breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 41: 579-82. PMID 1562529 DOI: 10.1016/0960-0760(92)90387-X  0.372
1992 Labrie F, Simard J, Luu-The V, Pelletier G, Bélanger A, Lachance Y, Zhao HF, Labrie C, Breton N, de Launoit Y. Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. The Journal of Steroid Biochemistry and Molecular Biology. 41: 421-35. PMID 1562516 DOI: 10.1016/0960-0760(92)90368-S  0.329
1992 Pinault S, Têtu B, Gagnon J, Monfette G, Dupont A, Labrie F. Transrectal ultrasound evaluation of local prostate cancer in patients treated with LHRH agonist and in combination with flutamide Urology. 39: 254-261. PMID 1546420 DOI: 10.1016/0090-4295(92)90301-C  0.327
1992 Simard J, Launoit Yd, Haagensen DE, Labrie F. Additive stimulatory action of glucocorticoids and androgens on basal and estrogen-repressed apolipoprotein-D messenger ribonucleic acid levels and secretion in human breast cancer cells. Endocrinology. 130: 1115-1121. PMID 1537279 DOI: 10.1210/Endo.130.3.1537279  0.339
1992 Labrie F, Sugimoto Y, Luu-The V, Simard J, Lachance Y, Bachvarov D, Leblanc G, Durocher F, Paquet N. Structure of human type II 5 alpha-reductase gene. Endocrinology. 131: 1571-3. PMID 1505484 DOI: 10.1210/Endo.131.3.1505484  0.302
1992 Couet J, Simard J, Martel C, Trudel C, Labrie Y, Labrie F. Regulation of 3-ketosteroid reductase messenger ribonucleic acid levels and 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase activity in rat liver by sex steroids and pituitary hormones. Endocrinology. 131: 3034-3044. PMID 1446638 DOI: 10.1210/Endo.131.6.1446638  0.337
1992 Dumont M, Luu-The V, Dupont E, Pelletier G, Labrie F. Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin. The Journal of Investigative Dermatology. 99: 415-21. PMID 1401999 DOI: 10.1111/1523-1747.Ep12616131  0.32
1992 Pelletier G, Dupont E, Simard J, Luu-The V, Bélanger A, Labrie F. Ontogeny and subcellular localization of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) in the human and rat adrenal, ovary and testis. The Journal of Steroid Biochemistry and Molecular Biology. 43: 451-67. PMID 1390295 DOI: 10.1016/0960-0760(92)90084-V  0.316
1992 Labrie F, Dupont A, Suburu R, Cusan L, Tremblay M, Gomez JL, Emond J. Serum prostate specific antigen as pre-screening test for prostate cancer. The Journal of Urology. 147: 846-51; discussion 8. PMID 1371560 DOI: 10.1016/S0022-5347(17)37402-5  0.319
1992 Martel C, Rhéaume E, Takahashi M, Trudel C, Couët J, Luu-The V, Simard J, Labrie F. Distribution of 17β-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues The Journal of Steroid Biochemistry and Molecular Biology. 41: 597-603. PMID 1314080 DOI: 10.1016/0960-0760(92)90390-5  0.318
1991 Zorilla R, Simard J, Labrie F, Pelletier G. Variations of pre-prosomatostatin MRNA levels in the hypothalamic periventricular nucleus during the rat estrous cycle. Molecular and Cellular Neuroscience. 2: 294-298. PMID 19912811 DOI: 10.1016/1044-7431(91)90058-V  0.319
1991 Takahashi M, Luu-The V, Labrie F. Inhibitory effect of synthetic progestins, 4-MA and cyanoketone on human placental 3 beta-hydroxysteroid dehydrogenase/5----4-ene-isomerase activity. The Journal of Steroid Biochemistry and Molecular Biology. 37: 231-6. PMID 2268554 DOI: 10.1016/0960-0760(90)90331-E  0.328
1991 Chedrese PJ, Zhang D, Luu The V, Labrie F, Juorio AV, Murphy BD. Regulation of mRNA expression of 3 beta-hydroxy-5-ene steroid dehydrogenase in porcine granulosa cells in culture: a role for the protein kinase-C pathway. Molecular Endocrinology (Baltimore, Md.). 4: 1532-8. PMID 2178218 DOI: 10.1210/Mend-4-10-1532  0.324
1991 Dupont E, Luu-The V, Labrie F, Pelletier G. Ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) in human adrenal gland performed by immunocytochemistry. Molecular and Cellular Endocrinology. 74: R7-10. PMID 2090513 DOI: 10.1016/0303-7207(90)90120-W  0.312
1991 Simard J, Melner MH, Breton N, Low KG, Zhao HF, Periman LM, Labrie F. Characterization of macaque 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase: structure and expression in steroidogenic and peripheral tissues in primate. Molecular and Cellular Endocrinology. 75: 101-10. PMID 2050270 DOI: 10.1016/0303-7207(91)90224-G  0.304
1991 Levesque C, Merand Y, Dufour JM, Labrie C, Labrie F. Synthesis and biological activity of new halo-steroidal antiestrogens. Journal of Medicinal Chemistry. 34: 1624-30. PMID 2033587 DOI: 10.1021/Jm00109A014  0.327
1991 Thériault C, Labrie F. Multiple steroid metabolic pathways in ZR-75-1 human breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 38: 155-64. PMID 2004038 DOI: 10.1016/0960-0760(91)90121-K  0.362
1991 Têtu B, Srigley JR, Boivin J, Dupont A, Monfette G, Pinault S, Labrie F. Effect of combination endocrine therapy (LHRH agonist and flutamide) on normal prostate and prostatic adenocarcinoma. A histopathologic and immunohistochemical study. The American Journal of Surgical Pathology. 15: 111-120. PMID 1989458 DOI: 10.1097/00000478-199102000-00002  0.357
1991 Dupont E, Labrie F, Luu-The V, Pelletier G. Localization of 17 beta-hydroxysteroid dehydrogenase throughout gestation in human placenta. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 39: 1403-7. PMID 1940311 DOI: 10.1177/39.10.1940311  0.31
1991 Dupont E, Rhéaume E, Simard J, Luu-The V, Labrie F, Pelletier G. Ontogenesis of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in the rat adrenal as revealed by immunocytochemistry and in situ hybridization. Endocrinology. 129: 2687-92. PMID 1935797 DOI: 10.1210/Endo-129-5-2687  0.322
1991 Marchetti B, Spinola PG, Pelletier G, Labrie F. A potential role for catecholamines in the development and progression of carcinogen-induced mammary tumors: Hormonal control of β-adrenergic receptors and correlation with tumor growth The Journal of Steroid Biochemistry and Molecular Biology. 38: 307-320. PMID 1848992 DOI: 10.1016/0960-0760(91)90102-B  0.341
1991 Dupont A, Cusan L, Gomez JL, Thibeault MM, Tremblay M, Labrie F. Prostate specific antigen and prostatic acid phosphatase for monitoring therapy of carcinoma of the prostate. The Journal of Urology. 146: 1064-7; discussion 1. PMID 1716697 DOI: 10.1016/S0022-5347(17)38001-1  0.308
1991 Martel C, Labrie C, Dupont E, Couet J, Trudel C, Rheaume E, Simard J, Luu-The V, Pelletier G, Labrie F. Regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase expression and activity in the hypophysectomized rat ovary: interactions between the stimulatory effect of human chorionic gonadotropin and the luteolytic effect of prolactin. Endocrinology. 127: 2726-37. PMID 1701125 DOI: 10.1210/Endo-127-6-2726  0.366
1991 Trudel C, Couët J, Martel C, Labrie C, Labrie F. Regulation of adrenal 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase expression and activity by adrenocorticotropin and corticosterone in the rat. Endocrinology. 129: 2077-84. PMID 1655393 DOI: 10.1210/Endo-129-4-2077  0.34
1991 Poulin R, Baker D, Poirier D, Labrie F. Multiple actions of synthetic 'progestins' on the growth of ZR-75-1 human breast cancer cells: An in vitro model for the simultaneous assay of androgen, progestin, estrogen, and glucocorticoid agonistic and antagonistic activities of steroids Breast Cancer Research and Treatment. 17: 197-210. PMID 1645605 DOI: 10.1007/Bf01806369  0.387
1991 Labrie C, Trudel C, Li S, Martel C, Couet J, Labrie F. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology. 128: 1673-1675. DOI: 10.1210/Endo-128-3-1673  0.392
1991 Labrie F. Endocrine therapy for prostate cancer. Endocrinology and Metabolism Clinics of North America. 20: 845-872. DOI: 10.1016/S0889-8529(18)30247-0  0.355
1991 Dupont E, Luu‐The V, Labrie F, Pelletier G. Ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) in human testis as studied by immunocytochemistry. Journal of Andrology. 12: 161-164. DOI: 10.1002/J.1939-4640.1991.Tb00240.X  0.321
1990 Lacoste D, Dubé D, Trudel C, Bélanger A, Labrie F. Normal gonadal functions and fertility after 23 months of treatment of prepubertal male and female dogs with the GnRh agonist [D-Trp6, des-Gly-NH2(10)]GnRH ethylamide. Journal of Andrology. 10: 456-65. PMID 2695507 DOI: 10.1002/J.1939-4640.1989.Tb00140.X  0.388
1990 Lacoste D, Dubé D, Bélanger A, Labrie F. Effect of 2-week combination therapy with the luteinizing hormone-releasing hormone (LHRH) agonist [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide and the antiandrogen flutamide on prostate structure and steroid levels in the dog. Molecular and Cellular Endocrinology. 67: 131-8. PMID 2693158 DOI: 10.1016/0303-7207(89)90202-5  0.407
1990 Lacoste D, Labrie F, Dubé D, Bélanger A, Tice T, Gilley RM, Pledger KL. Reversible inhibition of testicular androgen secretion by 3-, 5- and 6-month controlled-release microsphere formulations of the LH-RH agonist [D-Trp6, des-Gly-NH10(2)] LH-RH ethylamide in the dog. Journal of Steroid Biochemistry. 33: 1007-11. PMID 2689791 DOI: 10.1016/0022-4731(89)90253-7  0.351
1990 Toranzo D, Dupont E, Simard J, Labrie C, Couet J, Labrie F, Pelletier G. Regulation of pro-gonadotropin-releasing hormone gene expression by sex steroids in the brain of male and female rats. Molecular Endocrinology (Baltimore, Md.). 3: 1748-56. PMID 2514347 DOI: 10.1210/Mend-3-11-1748  0.378
1990 Dupont E, Zhao HF, Rhéaume E, Simard J, Luu-The V, Labrie F, Pelletier G. Localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in rat gonads and adrenal glands by immunocytochemistry and in situ hybridization. Endocrinology. 127: 1394-403. PMID 2387258 DOI: 10.1210/Endo-127-3-1394  0.346
1990 Tong Y, Zhao H, Labrie F, Pelletier G. Regulation of proopiomelanocortin messenger ribonucleic acid content by sex steriods in the arcuate nucleus of the female rat brain Neuroscience Letters. 112: 104-108. PMID 2385358 DOI: 10.1016/0304-3940(90)90330-C  0.329
1990 Bélanger A, Labrie F, Angeli A. Unconjugated and glucuronide steroid levels in human breast cyst fluid. Annals of the New York Academy of Sciences. 586: 93-100. PMID 2357014 DOI: 10.1111/J.1749-6632.1990.Tb17795.X  0.333
1990 Labrie F, Simard J, Poulin R, Hatton AC, Labrie C, Dauvois S, Zhao HF, Petitclerc L, Couët J, Dumont M. Potent antagonism between estrogens and androgens on GCDFP-15 expression and cell growth in the ZR-75-1 human breast cancer cells. Annals of the New York Academy of Sciences. 586: 174-87. PMID 2356999 DOI: 10.1111/J.1749-6632.1990.Tb17805.X  0.315
1990 Dupont E, Luu-The V, Labrie F, Pelletier G. Light microscopic immunocytochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4-isomerase in the gonads and adrenal glands of the guinea pig. Endocrinology. 126: 2906-9. PMID 2351102 DOI: 10.1210/Endo-126-6-2906  0.339
1990 Poulin R, Poirier D, Thériault C, Couture J, Bélanger A, Labrie F. Wide spectrum of steroids serving as substrates for the formation of lipoidal derivatives in ZR-75-1 human breast cancer cells. Journal of Steroid Biochemistry. 35: 237-47. PMID 2308338 DOI: 10.1016/0022-4731(90)90280-6  0.367
1990 Labrie F, Dupont A, Cusan L, Gomez J, Emond J, Monfette G. Combination therapy with flutamide and medical (LHRH agonist) or surgical castration in advanced prostate cancer: 7-year clinical experience The Journal of Steroid Biochemistry and Molecular Biology. 37: 943-950. PMID 2285608 DOI: 10.1016/0960-0760(90)90448-T  0.318
1990 Dauvois S, Simard J, Dumont M, Haagensen DE, Labrie F. Opposite effects of estrogen and the progestin R5020 on cell proliferation and GCDFP-15 expression in ZR-75-1 human breast cancer cells. Molecular and Cellular Endocrinology. 73: 171-178. PMID 2269395 DOI: 10.1016/0303-7207(90)90130-Z  0.342
1990 Cusan L, Dupont A, Bélanger A, Tremblay RR, Manhes G, Labrie F. Treatment of hirsutism with the pure antiandrogen flutamide. Journal of the American Academy of Dermatology. 23: 462-9. PMID 2212145 DOI: 10.1016/0190-9622(90)70241-9  0.326
1990 Rousseau L, Couture M, Dupont A, Labrie F, Couture N. Effect of combined androgen blockade with an LHRH agonist and flutamide in one severe case of male exhibitionism. The Canadian Journal of Psychiatry. 35: 338-341. PMID 2189544 DOI: 10.1177/070674379003500412  0.318
1990 Candas B, Lacoste D, Normand M, Labrie F. Model of the distribution and metabolism of the gonadotropin-releasing hormone (GnRH) agonist [D-Trp6,Des-Gly-NH2(10)]GnRH ethylamide in man. The Journal of Clinical Endocrinology and Metabolism. 70: 1046-54. PMID 2180974 DOI: 10.1210/Jcem-70-4-1046  0.306
1990 Chedrese PJ, Luu The V, Labrie F, Juorio AV, Murphy BD. Evidence for the regulation of 3 beta-hydroxysteroid dehydrogenase messenger RNA by human chorionic gonadotrophin in luteinized porcine granulosa cells. Endocrinology. 126: 2228-30. PMID 2156687 DOI: 10.1210/Endo-126-4-2228  0.327
1990 Marchetti B, Labrie F. Hormonal regulation of β-adrenergic receptors in the rat mammary gland during the estrous cycle and lactation: role of sex steroids and prolactin. Endocrinology. 126: 575-581. PMID 2152874 DOI: 10.1210/Endo-126-1-575  0.367
1990 Marchetti B, Fortier MA, Poyet P, Follea N, Pelletier G, Labrie F. β-Adrenergic receptors in the rat mammary gland during pregnancy and lactation: Characterization, distribution, and coupling to adenylate cyclase Endocrinology. 126: 565-574. PMID 2152873 DOI: 10.1210/Endo-126-1-565  0.353
1990 Martel C, Labrie C, Couët J, Dupont E, Trudel C, Luu-The V, Takahashi M, Pelletier G, Labrie F. Effects of human chorionic gonadotropin (hCG) and prolactin (PRL) on 3β-hydroxy-5-ene-steroid dehydrogenase/Δ5-Δ4 isomerase (3β-HSD) expression and activity in the rat ovary Molecular and Cellular Endocrinology. 72. PMID 2149342 DOI: 10.1016/0303-7207(90)90107-J  0.339
1990 Dupont A, Boucher H, Cusan L, Lacourciere Y, Emond J, Labrie F. Octreotide and bromocriptine in patients with stage D2 prostate cancer who relapsed during treatment with flutamide and castration. European Journal of Cancer and Clinical Oncology. 26: 770-771. PMID 2144174 DOI: 10.1016/0277-5379(90)90145-J  0.3
1990 Labrie F, Poulin R, Simard J, Zhao HF, Labrie C, Dauvois S, Dumont M, Hatton AC, Poirier D, Mérand Y. Interactions between estrogens, androgens, progestins, and glucocorticoids in ZR-75-1 human breast cancer cells. Annals of the New York Academy of Sciences. 595: 130-48. PMID 2142871 DOI: 10.1111/J.1749-6632.1990.Tb34288.X  0.402
1990 Bélanger A, Caron S, Labrie F, Naldoni C, Dogliotti L, Angeli A. Levels of eighteen non-conjugated and conjugated steroids in human breast cyst fluid: relationships with cyst type. European Journal of Cancer (Oxford, England : 1990). 26: 277-81. PMID 2141484 DOI: 10.1016/0277-5379(90)90222-F  0.318
1990 Labrie C, Simard J, Zhao HF, Pelletier G, Labrie F. Synthetic progestins stimulate prostatic binding protein messenger RNAs in the rat ventral prostate. Molecular and Cellular Endocrinology. 68: 169-79. PMID 2138099 DOI: 10.1016/0303-7207(90)90190-J  0.377
1990 Tong Y, Zhao H, Labrie F, Pelletier G. Effects of estrogens on the ultrastructural characteristics of female rat prolactin cells as evaluated by in situ hybridization in combination with immunogold staining technique. Neuroendocrinology. 52: 309-315. PMID 2124656 DOI: 10.1159/000125603  0.336
1990 Zorrilla R, Simard J, Rhéaume E, Labrie F, Pelletier G. Multihormonal control of pre-pro-somatostatin mRNA levels in the periventricular nucleus of the male and female rat hypothalamus. Neuroendocrinology. 52: 527-536. PMID 1980724 DOI: 10.1159/000125639  0.303
1990 Simard J, Labrie C, Mérand Y, Dufour J, Lévesque C, Labrie F. Pure Antagonistic Effect of a New Steroidal Antiestrogen in Rat Anterior Pituitary Cells in Culture and in Mouse Uterus Annals of the New York Academy of Sciences. 595: 425-427. DOI: 10.1111/J.1749-6632.1990.Tb34325.X  0.323
1990 Thériault C, Poulin R, Tremblay S, Poirier D, Labrie F. Hormonal Regulation of Estradiol 17?-Hydroxysteroid Dehydrogenase Activity in the ZR-75-1 Human Breast Cancer Cell Line Annals of the New York Academy of Sciences. 595: 419-421. DOI: 10.1111/J.1749-6632.1990.Tb34323.X  0.314
1990 Dauvois S, Li S, Labrie F. Antagonism between Androgens and Estrogens on the Growth of Mammary Carcinoma in Vivo Annals of the New York Academy of Sciences. 595: 413-415. DOI: 10.1111/J.1749-6632.1990.Tb34321.X  0.301
1990 Bélanger C, Veilleux R, Labrie F. Stimulatory Effects of Androgens, Estrogens, Progestins, and Dexamethasone on the Growth of the LNCaP Human Prostate Cancer Cells Annals of the New York Academy of Sciences. 595: 399-402. DOI: 10.1111/J.1749-6632.1990.Tb34316.X  0.363
1990 Labrie C, Simard J, Poulin M, Bélanger A, Pelletier G, Labrie F. Influence of the Duration of Androgen Deprivation on the Sensitivity of the Rat Ventral Prostate to Dehydroepiandrosterone and Androstenedione Annals of the New York Academy of Sciences. 595: 392-394. DOI: 10.1111/J.1749-6632.1990.Tb34314.X  0.335
1990 Lacoste D, Bélanger A, Labrie F. Biosynthesis and Degradation of Androgens in Human Prostatic Cancer Cell Lines Annals of the New York Academy of Sciences. 595: 389-391. DOI: 10.1111/J.1749-6632.1990.Tb34313.X  0.325
1990 Dupont A, Dupont P, Belanger A, Mailoux J, Cusan L, Labrie F. Hormonal and biochemical changes during treatment of endometriosis with the luteinizing hormone-releasing hormone (LH-RH) agonist [D-Trp6,des-Gly-NH210]LH-RH ethylamide Fertility and Sterility. 54: 227-232. DOI: 10.1016/S0015-0282(16)53694-2  0.364
1989 Lacoste D, St-Arnaud R, Caron S, Belanger A, Labrie F. The rise in testicular androgens during the first days of treatment with an LHRH agonist in the dog can be blocked by aminoglutethimide or ketoconazole. Journal of Steroid Biochemistry. 31: 963-70. PMID 3059065 DOI: 10.1016/0022-4731(88)90339-1  0.391
1989 Tong Y, Simard J, Labrie C, Zhao HF, Labrie F, Pelletier G. Inhibitory effect of androgen on estrogen-induced prolactin messenger ribonucleic acid accumulation in the male rat anterior pituitary gland. Endocrinology. 125: 1821-8. PMID 2791967 DOI: 10.1210/Endo-125-4-1821  0.379
1989 Labrie F, Dupont A, Bélanger A, Cusan L, Brochu M, Turina E, Pinault S, Lacourciere Y, Emond J. Anti-hormone treatment for prostate cancer relapsing after treatment with flutamide and castration. Addition of aminoglutethimide and low dose hydrocortisone to combination therapy. British Journal of Urology. 63: 634-8. PMID 2752257 DOI: 10.1111/J.1464-410X.1989.Tb05260.X  0.34
1989 Simard J, Hatton AC, Labrie C, Dauvois S, Zhao HF, Haagensen DE, Labrie F. Inhibitory effect of estrogens on GCDFP-15 mRNA levels and secretion in ZR-75-1 human breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 3: 694-702. PMID 2725533 DOI: 10.1210/Mend-3-4-694  0.365
1989 Tong Y, Zhao HF, Simard J, Labrie F, Pelletier G. Electron Microscopic Autoradiographic Localization of Prolactin mRNA in Rat Pituitary Journal of Histochemistry and Cytochemistry. 37: 567-571. PMID 2703695 DOI: 10.1177/37.5.2703695  0.338
1989 Labrie F, Dupont A, Cusan L, Manhès G, Bergeron N, Lacourcière Y, Pineault S, Bélanger A, Monfette G, Emond J. Combination therapy with castration and flutamide: today's treatment of choice for prostate cancer. Journal of Steroid Biochemistry. 33: 817-21. PMID 2689788 DOI: 10.1016/0022-4731(89)90499-8  0.326
1989 Lacoste D, Caron S, Bélanger A, Labrie F. Effect of 3-week treatment with [D-Trp6, des-Gly-NH10(2)]LHRH ethylamide, aminoglutethimide, ketoconazole or flutamide alone or in combination on testicular, serum, adrenal and prostatic steroid levels in the dog. Journal of Steroid Biochemistry. 33: 233-42. PMID 2671505 DOI: 10.1016/0022-4731(89)90299-9  0.414
1989 Poulin R, Dufour JM, Labrie F. Progestin inhibition of estrogen-dependent proliferation in ZR-75-1 human breast cancer cells: antagonism by insulin. Breast Cancer Research and Treatment. 13: 265-76. PMID 2667655 DOI: 10.1007/Bf02106576  0.342
1989 Poulin R, Simard J, Labrie C, Petitclerc L, Dumont M, Lagace L, Labrie F. Down-regulation of estrogen receptors by androgens in the ZR-75-1 human breast cancer cell line. Endocrinology. 125: 392-9. PMID 2661209 DOI: 10.1210/Endo-125-1-392  0.376
1989 Dumont M, Dauvois S, Simard J, Garcia T, Schachter B, Labrie F. Antagonism between estrogens and androgens on GCDFP-15 gene expression in ZR-75-1 cells and correlation between GCDFP-15 and estrogen as well as progesterone receptor expression in human breast cancer. Journal of Steroid Biochemistry. 34: 397-402. PMID 2626033 DOI: 10.1016/0022-4731(89)90115-5  0.361
1989 Tong Y, Zhao H, Labrie F, Pelletier G. Ontogeny of prolactin mRNA in the rat pituitary gland as evaluated by in situ hybridization Molecular and Cellular Endocrinology. 67: 11-16. PMID 2612736 DOI: 10.1016/0303-7207(89)90225-6  0.305
1989 Poulin R, Merand Y, Poirier D, Levesque C, Dufour JM, Labrie F. Antiestrogenic properties of keoxifene, trans-4-hydroxytamoxifen, and ICI 164384, a new steroidal antiestrogen, in ZR-75-1 human breast cancer cells. Breast Cancer Research and Treatment. 14: 65-76. PMID 2605344 DOI: 10.1007/Bf01805977  0.357
1989 Marchetti B, Spinola PG, Plante M, Poyet P, Folléa N, Pelletier G, Labrie F. Beta-adrenergic receptors in DMBA-induced rat mammary tumors: correlation with progesterone receptor and tumor growth. Breast Cancer Research and Treatment. 13: 251-263. PMID 2569332 DOI: 10.1007/Bf02106575  0.333
1989 Dauvois S, Spinola PG, Labrie F. Additive inhibitory effects of bromocryptine (CB-154) and medroxyprogesterone acetate (MPA) on dimethylbenz[a]anthracene (DMBA)-induced mammary tumors in the rat European Journal of Cancer and Clinical Oncology. 25: 891-897. PMID 2525471 DOI: 10.1016/0277-5379(89)90137-5  0.305
1989 Poulin R, Baker D, Poirier D, Labrie F. Androgen and glucocorticoid receptor-mediated inhibition of cell proliferation by medroxyprogesterone acetate in ZR-75-1 human breast cancer cells Breast Cancer Research and Treatment. 13: 161-172. PMID 2525057 DOI: 10.1007/Bf01806528  0.372
1989 Dauvois S, Labrie F. Androstenedione and androst-5-ene-3β,17β-diol stimulate DMBA-induced rat mammary tumors — role of aromatase Breast Cancer Research and Treatment. 13: 61-69. PMID 2495831 DOI: 10.1007/Bf01806551  0.342
1988 Luthy I, Caron S, Bélanger A, Labrie F. Effects of flutamide, a pure antiandrogen, on endocrine parameters, in the adult female rat. Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology. 1: 151-68. PMID 3503483 DOI: 10.3109/09513598709030679  0.376
1988 Labrie F, Veilleux R, Fournier A. Low Androgen Levels Induce the Development of Androgen-Hypersensitive Cell Clones in Shionogi Mouse Mammary Carcinoma Cells in Culture Journal of the National Cancer Institute. 80: 1138-1147. PMID 3411627 DOI: 10.1093/Jnci/80.14.1138  0.358
1988 Luthy IA, Begin D, Labrie F. Mediation by the Androgen Receptor of the Stimulatory and Antiandrogenic Actions of 17β-Estradiol on the Growth of Androgen-Sensitive Shionogi Mammary Carcinoma Cells in Culture Endocrinology. 123: 1418-1424. PMID 3402389 DOI: 10.1210/Endo-123-3-1418  0.342
1988 Labrie F, Veilleux R, Fournier A. Maintenance of Androgen Responsiveness by Glucocorticoids in Shionogi Mammary Carcinoma Cells in Culture1 Journal of the National Cancer Institute. 80: 966-970. PMID 3398072 DOI: 10.1093/Jnci/80.12.966  0.348
1988 St-Arnaud R, Poyet P, Walker P, Labrie F. Androgens modulate epidermal growth factor receptor levels in the rat ventral prostate. Molecular and Cellular Endocrinology. 56: 21-27. PMID 3371544 DOI: 10.1016/0303-7207(88)90004-4  0.372
1988 Labrie F, Dupont A, Cusan L, Giguere M, Bergeron N, Borsanyi JP, Lacourciere Y, Belanger A, Emond J, Monfette G. Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in previously untreated patients with clinical stage D2 prostate cancer: today's therapy of choice. Journal of Steroid Biochemistry. 30: 107-17. PMID 3290578 DOI: 10.1016/0022-4731(88)90083-0  0.338
1988 Dupont A, Labrie F, Giguere M, Borsanyi JP, Lacourciere Y, Bergeron N, Cusan L, Belanger A, Emond J. Combination therapy with flutamide and [D-Trp6]LHRH ethylamide for stage C prostatic carcinoma. European Journal of Cancer & Clinical Oncology. 24: 659-66. PMID 3289945 DOI: 10.1016/0277-5379(88)90296-9  0.322
1988 Lacoste D, St-Arnaud R, Bélanger A, Labrie F. A pure antiandrogen does not interfere with the LHRH agonist-induced blockade of testicular androgen secretion in the dog Molecular and Cellular Endocrinology. 56: 141-147. PMID 3286322 DOI: 10.1016/0303-7207(88)90018-4  0.415
1988 Bélanger A, Giasson M, Couture J, Dupont A, Cusan L, Labrie F. Plasma levels of hydroxy-flutamide in patients with prostatic cancer receiving the combined hormonal therapy: an LHRH agonist and flutamide. The Prostate. 12: 79-84. PMID 3279409 DOI: 10.1002/Pros.2990120110  0.355
1988 Moorjani S, Dupont A, Labrie F, Lupien PJ, Gagné C, Brun D, Giguère M, Bélanger A, Cusan L. Changes in plasma lipoproteins during various androgen suppression therapies in men with prostatic carcinoma: effects of orchiectomy, estrogen, and combination treatment with luteinizing hormone-releasing hormone agonist and flutamide. The Journal of Clinical Endocrinology and Metabolism. 66: 314-22. PMID 3276721 DOI: 10.1210/Jcem-66-2-314  0.324
1988 Poulin R, Baker D, Labrie F. Androgens inhibit basal and estrogen-induced cell proliferation in the ZR-75-1 human breast cancer cell line Breast Cancer Research and Treatment. 12: 213-225. PMID 3242650 DOI: 10.1007/Bf01805942  0.352
1988 Hubert JF, Thibault L, Turcotte R, Labrie F. Androgens exert selective effects on protein kinase C induced LH and FSH release in rat anterior pituitary cells in culture. Neuroendocrinology. 48: 360-6. PMID 3145469 DOI: 10.1159/000125035  0.368
1988 Dube D, Pelletier G, Labrie F. The luteinizing hormone-releasing hormone (LHRH) agonist, [D-TRP6, DES-GLY-NH210]-LHRH ethylamide, has no direct effect on spermatogenesis in the rat Biology of Reproduction. 38: 1165-1170. PMID 3044454 DOI: 10.1095/Biolreprod38.5.1165  0.394
1988 Bégin D, Luthy IA, Labrie F. Adrenal precursor C19 steroids are potent stimulators of growth of androgen-sensitive mouse mammary carcinoma Shionogi cells in vitro Molecular and Cellular Endocrinology. 58: 213-219. PMID 2974815 DOI: 10.1016/0303-7207(88)90157-8  0.308
1988 Labrie C, Belanger A, Labrie F. Androgenic activity of dehydroepiandrosterone and androstenedione in the rat ventral prostate. Endocrinology. 123: 1412-7. PMID 2969802 DOI: 10.1210/Endo-123-3-1412  0.384
1988 Simard J, Vincent A, Duchesne R, Labrie F. Full oestrogenic activity of C19-Δ5 adrenal steroids in rat pituitary lactotrophs and somatotrophs Molecular and Cellular Endocrinology. 55: 233-242. PMID 2965660 DOI: 10.1016/0303-7207(88)90138-4  0.38
1988 Brochu M, Bélanger A, Dupont A, Cusan L, Labrie F. Effects of flutamide and aminoglutethimide on plasma 5 alpha-reduced steroid glucuronide concentrations in castrated patients with cancer of the prostate. Journal of Steroid Biochemistry. 28: 619-22. PMID 2961945 DOI: 10.1016/0022-4731(87)90388-8  0.342
1988 Labrie F, Veilleux R, Fournier A. Glucocorticoids stimulate the growth of mouse mammary carcinoma Shionogi cells in culture. Molecular and Cellular Endocrinology. 58: 207-211. PMID 2850248 DOI: 10.1016/0303-7207(88)90156-6  0.325
1988 Marchetti B, Poulin R, Plante M, Labrie F. Castration levels of plasma testosterone have potent stimulatory effects on androgen-sensitive parameters in the rat prostate Journal of Steroid Biochemistry. 31: 411-419. PMID 2845194 DOI: 10.1016/0022-4731(88)90309-3  0.378
1988 Marchetti B, Labrie F. Characteristics of flutamide action on prostatic and testicular functions in the rat Journal of Steroid Biochemistry. 29: 691-698. PMID 2838689 DOI: 10.1016/0022-4731(88)90170-7  0.399
1988 Crim LW, Arnaud RS, Lavoie M, Labrie F. A study of LH-RH receptors in the pituitary gland of the winter flounder (Pseudopleuronectes americanus Walbaum). General and Comparative Endocrinology. 69: 372-377. PMID 2834259 DOI: 10.1016/0016-6480(88)90027-5  0.355
1988 Pelletier G, Labrie C, Simard J, Duval M, Martinoli MG, Zhao H, Labrie F. Effects of sex steroids on regulation of the levels of C1 peptide of rat prostatic steroid-binding protein mRNA evaluated by in-situ hybridization Journal of Molecular Endocrinology. 1: 213-223. PMID 2475128 DOI: 10.1677/Jme.0.0010213  0.351
1988 Luthy IA, Begin DJ, Labrie F. Androgenic activity of synthetic progestins and spironolactone in androgen-sensitive mouse mammary carcinoma (Shionogi) cells in culture Journal of Steroid Biochemistry. 31: 845-852. PMID 2462135 DOI: 10.1016/0022-4731(88)90295-6  0.305
1988 Simard J, Labrie C, Hubert JF, Labrie F. Modulation by sex steroids and [D-Trp6, Des-Gly-NH2(10)]luteinizing hormone (LH)-releasing hormone ethylamide of alpha-subunit and LH beta messenger ribonucleic acid levels in the rat anterior pituitary gland. Molecular Endocrinology (Baltimore, Md.). 2: 775-84. PMID 2459604 DOI: 10.1210/Mend-2-9-775  0.381
1988 Hubert JF, Simard J, Gagné B, Barden N, Labrie F. Effect of luteinizing hormone releasing hormone (LHRH) and [D-Trp6, des-Gly-NH2(10)]LHRH ethylamide on alpha-subunit and LH beta messenger ribonucleic acid levels in rat anterior pituitary cells in culture. Molecular Endocrinology (Baltimore, Md.). 2: 521-7. PMID 2458526 DOI: 10.1210/Mend-2-6-521  0.369
1988 Plante M, Lapointe S, Labrie F. Stimulatory effect of synthetic progestins currently used for the treatment of prostate cancer on growth of the androgen-sensitive shionogi tumor in mice Journal of Steroid Biochemistry. 31: 61-64. PMID 2456423 DOI: 10.1016/0022-4731(88)90206-3  0.332
1987 Luthy I, Labrie F. Development of androgen resistance in mouse mammary tumor cells can be prevented by the antiandrogen flutamide. The Prostate. 10: 89-94. PMID 3822919 DOI: 10.1002/Pros.2990100112  0.357
1987 Dube D, Pelletier G, Labrie F. Morphological studies of the canine pituitary luteinizing hormone (LH) cells after long-term treatment with the LH-releasing hormone (LHRH) agonist [D-Trp6]LHRH ethylamide Endocrinology. 120: 589-594. PMID 3542506 DOI: 10.1210/Endo-120-2-589  0.368
1987 Labrie F, Dupont A, Bélanger A, Cusan L, Giguère M, Lacourcière Y, Luthy I, Bégin D, Labrie C, Simard J. Combination therapy in stage C and D prostatic cancer: rationale and five year clinical experience. Cancer Metastasis Reviews. 6: 615-36. PMID 3327635 DOI: 10.1007/Bf00047470  0.394
1987 Labrie F, Dupont A, Belanger A, Lachance R. Flutamide eliminates the risk of disease flare in prostatic cancer patients treated with a luteinizing hormone-releasing hormone agonist. The Journal of Urology. 138: 804-6. PMID 3309363 DOI: 10.1016/S0022-5347(17)43380-5  0.397
1987 Poyet P, Labrie F. Characterization of β-adrenergic receptors in dispersed rat testicular interstitial cells Journal of Andrology. 8: 7-13. PMID 3030990 DOI: 10.1002/J.1939-4640.1987.Tb02409.X  0.319
1987 Simard J, Labrie F. Adrenal C19-5-ene steroids induce full estrogenic responses in rat pituitary gonadotrophs Journal of Steroid Biochemistry. 26: 539-546. PMID 2953941 DOI: 10.1016/0022-4731(87)90005-7  0.411
1987 Simard J, Lefèvre G, Labrie F. Somatostatin prevents the desensitizing action of growth hormone-releasing factor on growth hormone release. Peptides. 8: 199-205. PMID 2884644 DOI: 10.1016/0196-9781(87)90090-8  0.33
1987 Labrie C, Cusan L, Plante M, Lapointe S, Labrie F. Analysis of the androgenic activity of synthetic "progestins" currently used for the treatment of prostate cancer Journal of Steroid Biochemistry. 28: 379-384. PMID 2444770 DOI: 10.1016/0022-4731(87)91054-5  0.355
1987 St-Arnaud R, Lachance R, Labrie F. Characteristics of radioimmunoassays for the alpha- and beta-subunits of human luteinizing hormone. Journal of Immunoassay. 8: 97-114. PMID 2435761 DOI: 10.1080/01971528708063056  0.323
1987 Poulin R, Poirier D, Labrie F. Androgens decrease the number of estrogen receptors in the ZR-75-1 human breast cancer cell line Journal of Steroid Biochemistry. 28: 157. DOI: 10.1016/0022-4731(87)91555-X  0.313
1987 Spinola P, Marchetti B, Bèlanger A, Labrie F. Steroid levels in dimethylbenz(A)anthracene(DMBA)-induced mammary tumors (MT) in the rat stimulated by adrenal steroids: correlation with progesterone receptor levels and tumor growth Journal of Steroid Biochemistry. 28: 137. DOI: 10.1016/0022-4731(87)91501-9  0.309
1986 Simard J, Luthy I, Guay J, Bélanger A, Labrie F. Characteristics of interaction of the antiandrogen flutamide with the androgen receptor in various target tissues Molecular and Cellular Endocrinology. 44: 261-270. PMID 3956856 DOI: 10.1016/0303-7207(86)90132-2  0.342
1986 Hubert JF, Vincent A, Labrie F. Estrogenic activity of phenol red in rat anterior pituitary cells in culture. Biochemical and Biophysical Research Communications. 141: 885-91. PMID 3814125 DOI: 10.1016/S0006-291X(86)80125-5  0.378
1986 Labrie F, Veilleux R. A wide range of sensitivities to androgens develops in cloned Shionogi mouse mammary tumor cells. The Prostate. 8: 293-300. PMID 3703748 DOI: 10.1002/Pros.2990080309  0.367
1986 Arnaud RS, Lachance R, Dupont A, Labrie F. Serum luteinizing hormone (LH) biological activity in castrated patients with cancer of the prostate receiving a pure antiandrogen and in estrogen-pretreated patients treated with an LH-releasing hormone agonist and antiandrogen. The Journal of Clinical Endocrinology and Metabolism. 63: 297-302. PMID 3522618 DOI: 10.1210/Jcem-63-2-297  0.401
1986 St-Arnaud R, Lachance R, Kelly SJ, Belanger A, Dupont A, Labrie F. Loss of luteinizing hormone bioactivity in patients with prostatic cancer treated with an LHRH agonist and a pure antiandrogen. Clinical Endocrinology. 24: 21-30. PMID 3519004 DOI: 10.1111/J.1365-2265.1986.Tb03250.X  0.409
1986 Labrie F, Dupont A, Bélanger A, St-Arnaud R, Giguère M, Lacourcière Y, Emond J, Monfette G. Treatment of prostate cancer with gonadotropin-releasing hormone agonists. Endocrine Reviews. 7: 67-74. PMID 3514203 DOI: 10.1210/Edrv-7-1-67  0.41
1986 Labrie F, Dupont A, Giguere M, Borsanyi JP, Belanger A, Lacourciere Y, Emond J, Monfette G. Advantages of the combination therapy in previously untreated and treated patients with advanced prostate cancer. Journal of Steroid Biochemistry. 25: 877-83. PMID 3100871 DOI: 10.1016/0022-4731(86)90319-5  0.34
1986 Simard J, Hubert JF, Hosseinzadeh T, Labrie F. Stimulation of growth hormone release and synthesis by estrogens in rat anterior pituitary cells in culture. Endocrinology. 119: 2004-11. PMID 3095099 DOI: 10.1210/Endo-119-5-2004  0.371
1986 Simard J, Hubert JF, Labrie F, Israël-Assayag E, Heisler S. Atrial natriuretic factor-induced cGMP accumulation in rat anterior pituitary cells in culture is not coupled to hormonal secretion. Regulatory Peptides. 15: 269-78. PMID 3024238 DOI: 10.1016/0167-0115(86)90068-6  0.369
1986 Poyet P, Gagne B, Labrie F. Characteristics of the β-adrenergic stimulation of adenylate cyclase activity in rat ventral prostate and its modulation by androgens The Prostate. 9: 237-245. PMID 3022260 DOI: 10.1002/Pros.2990090304  0.389
1986 Dube D, Poyet P, Pelletier G, Labrie F. Radioautographic localization of β-adrenergic receptors in the rat ventral prostate Journal of Andrology. 7: 169-174. PMID 3013821 DOI: 10.1002/J.1939-4640.1986.Tb00904.X  0.377
1986 Spinola PG, Marchetti B, Labrie F. Adrenal steroids stimulate growth and progesterone receptor levels in rat uterus and DMBA-induced mammary tumors. Breast Cancer Research and Treatment. 8: 241-248. PMID 2954599 DOI: 10.1007/Bf01807337  0.346
1986 Poyet P, Gagne B, Lavoie M, Labrie F. Characteristics of the β-adrenergic receptor in the rat ventral prostate using [125I]cyanopindolol Molecular and Cellular Endocrinology. 48: 59-67. PMID 2877909 DOI: 10.1016/0303-7207(86)90166-8  0.359
1986 Simard J, Labrie F. Characteristics of the desensitization of growth hormone and cyclic AMP responses to growth hormone-releasing factor and prostaglandin E2 in rat anterior pituitary cells in culture. Molecular and Cellular Endocrinology. 46: 79-89. PMID 2423397 DOI: 10.1016/0303-7207(86)90072-9  0.346
1986 Heisler S, Simard J, Assayag E, Mehri Y, Labrie F. Atrial natriuretic factor does not affect basal, forskolin- and CRF-stimulated adenylate cyclase activity, cAMP formation or ACTH secretion, but does stimulate cGMP synthesis in anterior pituitary. Molecular and Cellular Endocrinology. 44: 125-131. PMID 2419182 DOI: 10.1016/0303-7207(86)90054-7  0.339
1986 Parmar H, Phillips R, Lightman S, Edwards L, Labrie F, Dupont A, Bélanger A. LHRH ANALOGUES IN PROSTATIC CANCER The Lancet. 327: 445-446. DOI: 10.1016/S0140-6736(86)92404-9  0.313
1986 Labrie F, Dupont A, Belanger A, Poyet P, Giguere M, Lacourciere Y, Emond J, Monfette G, Borsanyi J, Urwin G. COMBINED TREATMENT WITH FLUTAMIDE AND SURGICAL OR MEDICAL (LHRH AGONIST) CASTRATION IN METASTATIC PROSTATIC CANCER The Lancet. 327: 48-49. DOI: 10.1016/S0140-6736(86)91935-5  0.317
1986 Bélanger A, Labrie F, Dupont A. Androgen levels in prostatic tissue of patients with carcinoma of the prostate treated with the combined therapy using an LHRH agonist and a pure antiandrogen European Journal of Cancer and Clinical Oncology. 22: 742. DOI: 10.1016/0277-5379(86)90276-2  0.329
1985 Tremblay Y, Bélanger A, Lacoste D, Giasson M, Labrie F. Selective inhibition of spermatogenesis in the presence of normal libido following combined treatment with an LHRH agonist and testosterone in the dog. Contraception. 30: 585-8. PMID 6397329 DOI: 10.1016/0010-7824(84)90008-8  0.393
1985 Raymond V, Leung PC, Veilleux R, Labrie F. Vasopressin rapidly stimulates phosphatidic acid-phosphatidylinositol turnover in rat anterior pituitary cells. Febs Letters. 182: 196-200. PMID 3972124 DOI: 10.1016/0014-5793(85)81183-2  0.334
1985 Poyet P, Labrie F. Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate. Molecular and Cellular Endocrinology. 42: 283-288. PMID 3930312 DOI: 10.1016/0303-7207(85)90059-0  0.369
1985 Labrie F, Dupont A, Belanger A, Lachance R, Giguere M. Long term treatment with luteinising hormone releasing hormone agonists and maintenance of serum testosterone to castration concentrations. British Medical Journal (Clinical Research Ed.). 291: 369-70. PMID 3926197 DOI: 10.1016/S0022-5347(17)46100-3  0.369
1985 Simard J, Labrie F. Keoxifene shows pure antiestrogenic activity in pituitary gonadotrophs Molecular and Cellular Endocrinology. 39: 141-144. PMID 3884413 DOI: 10.1016/0303-7207(85)90131-5  0.371
1985 Lemay A, Faure N, Labrie F, Fazekas ATA. Inhibition of ovulation during discontinuous intranasal luteinizing hormone-releasing hormone agonist dosing in combination with gestagen-induced bleeding Fertility and Sterility. 43: 868-877. PMID 3158551 DOI: 10.1016/S0015-0282(16)48614-0  0.356
1985 Labrie F, Dupont A, Belanger A, Giguere M, Lacoursiere Y, Emond J, Monfette G, Bergeron V. Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in advanced prostate cancer: a marked improvement in response and survival. Journal of Steroid Biochemistry. 23: 833-41. PMID 2934579 DOI: 10.1016/S0022-4731(85)80024-8  0.316
1985 Marchetti B, Plante M, Poulin R, Labrie F. 35 Dramatic response of prostatic weight and ornithine decarboxylase to low levels of testosterone in castrated rats Journal of Steroid Biochemistry. 23: 32. DOI: 10.1016/0022-4731(85)90358-9  0.333
1985 Simard J, Labrie F. 26 Blockage of the potent estrogenic activity of 5-androstene-3 8, 17 β-diol (Δ5-diol) and dehydroepiandrosterone (DHEA) by the antiestrogen LY-156758 in rat anterior pituitary cells in culture Journal of Steroid Biochemistry. 23: 27. DOI: 10.1016/0022-4731(85)90349-8  0.34
1984 Raymond V, Leung PCK, Veilleux R, Lefèvre G, Labrie F. LHRH rapidly stimulates phosphatidylinositol metabolism in enriched gonadotrophs. Molecular and Cellular Endocrinology. 36: 157-164. PMID 6432603 DOI: 10.1016/0303-7207(84)90031-5  0.343
1984 Labrie F, Dupont A, Bélanger A, Emond J, Monfette G. Simultaneous administration of pure antiandrogens, a combination necessary for the use of luteinizing hormone-releasing hormone agonists in the treatment of prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 81: 3861-3863. PMID 6427777 DOI: 10.1073/Pnas.81.12.3861  0.406
1984 Raynaud JP, Azadian-Boulanger G, Bouton MM, Colin MC, Faure N, Fernand-Proulx L, Gautray JP, Husson JM, Jolivet A, Kelly P, Labrie F, Ojasoo T, Précigoux G. RU 16117, an orally active estriol-like weak estrogen Journal of Steroid Biochemistry. 20: 981-993. PMID 6427528 DOI: 10.1016/0022-4731(84)90008-6  0.359
1984 Massicotte J, Lagacé L, Godbout M, Labrie F. Modulation of rat pituitary gonadotrophin secretion by porcine granulosa cell 'inhibin', LH releasing hormone and sex steroids in rat anterior pituitary cells in culture. Journal of Endocrinology. 100: 133-140. PMID 6420491 DOI: 10.1677/Joe.0.1000133  0.387
1984 Massicotte J, Lagace L, Labrie F, Dorrington JH. Modulation of gonadotropin secretion by Sertoli cell inhibin, LHRH, and sex steroids. American Journal of Physiology-Endocrinology and Metabolism. 247. PMID 6388347 DOI: 10.1152/Ajpendo.1984.247.4.E495  0.391
1984 Labrie F. A new approach in the hormonal treatment of prostate cancer: complete instead of partial blockade of androgens. International Journal of Andrology. 7: 1-4. PMID 6370872 DOI: 10.1111/J.1365-2605.1984.Tb00755.X  0.353
1984 Marchetti B, Labrie F. Further characterization of the direct inhibitory effect of LHRH agonists at the testicular level in the rat Journal of Steroid Biochemistry. 20: 339-342. PMID 6323867 DOI: 10.1016/0022-4731(84)90229-2  0.39
1984 Labrie F, Giguere V, Proulx L, Lefevre G. Interactions between CRF, epinephrine, vasopressin and glucocorticoids in the control of acth secretion Journal of Steroid Biochemistry. 20: 153-160. PMID 6323861 DOI: 10.1016/0022-4731(84)90202-4  0.37
1984 Carmichael R, Belanger A, Caron S, Labrie F, Sairam MR. Comparative effects of LHRH agonist and ovine LH administration on testicular steroidogenesis in intact adult rat. Steroids. 40: 641-9. PMID 6318398 DOI: 10.1016/0039-128X(82)90004-6  0.383
1984 Tremblay Y, Bélanger A, Labrie F, Frenette G, Dubé JY, Tremblay RR. Characteristics of the inhibitory effect of chronic treatment with an LHRH agonist on testicular steroidogenesis in the dog. The Prostate. 5: 631-8. PMID 6208541 DOI: 10.1002/Pros.2990050609  0.409
1984 Heisler S, Veilleux R, Labrie F. PHI stimulates ACTH release from pituitary tumor cell. Molecular and Cellular Endocrinology. 35: 183-188. PMID 6203787 DOI: 10.1016/0303-7207(84)90015-7  0.352
1984 Labrie F, Belanger A, Dupont A, Emond J, Lacoursiere Y, Monfette G. Combined Treatment With Lhrh Agonist And Pure Antiandrogen In Advanced Carcinoma Of Prostate The Lancet. 324: 1090. PMID 6150154 DOI: 10.1016/S0140-6736(84)91521-6  0.311
1984 Massicotte J, Lachance R, Labrie F. Modulation of cyclic AMP formation and progesterone secretion by human chorionic gonadotropin, epinephrine, buserelin and prostaglandins in normal or human chorionic gonadotropin desensitized rat immature luteal cells in monolayer culture Journal of Steroid Biochemistry. 21: 217-226. PMID 6092780 DOI: 10.1016/0022-4731(84)90273-5  0.377
1984 Michel D, Lefèvre G, Labrie F. Dexamethasone is a potent stimulator of growth hormone-releasing factor-induced cyclic AMP accumulation in the adenohypophysis Life Sciences. 35: 597-602. PMID 6087069 DOI: 10.1016/0024-3205(84)90254-6  0.367
1984 Bélanger A, Dupont A, Labrie F. Inhibition of basal and adrenocorticotropin-stimulated plasma levels of adrenal androgens after treatment with an antiandrogen in castrated patients with prostatic cancer. The Journal of Clinical Endocrinology and Metabolism. 59: 422-6. PMID 6086697 DOI: 10.1210/Jcem-59-3-422  0.383
1984 Lefebvre FA, Bélanger A, Pelletier G, Labrie F. Recovery of gonadal functions in the adult male rat following cessation of five-month daily treatment with an LHRH agonist. Journal of Andrology. 5: 181-92. PMID 6086556 DOI: 10.1002/J.1939-4640.1984.Tb02391.X  0.375
1984 Rousseau L, Couture M, Dupont A, Labrie F. Preliminary study on the sexuality of patients treated for prostatic cancer (surgical castration + antiandrogen or LHRH-a / antiandrogen) Journal of Steroid Biochemistry. 20: 1413. DOI: 10.1016/0022-4731(84)90511-9  0.305
1984 St-Arnaud R, Lachance R, Bélanger A, Dupont A, Labrie F. Pituitary desensitization and loss of luteinizing hormone bioactivity in men with cancer of the prostate following chronic treatment with an lhrh agonist and an antiandrogen Journal of Steroid Biochemistry. 20: 1408. DOI: 10.1016/0022-4731(84)90500-4  0.37
1984 Labrie C, Labrie F, Dupont A, Lacoursière Y. Ria measurement of serum pap, a reliable follow-up parameter in prostate cancer Journal of Steroid Biochemistry. 20: 1396. DOI: 10.1016/0022-4731(84)90477-1  0.31
1984 Dupont A, Labrie F, Bélanger A, Lacoursière Y. Nists alone in prostate cancer induces the development of androgen-insensitive cell clones Journal of Steroid Biochemistry. 20: 1391. DOI: 10.1016/0022-4731(84)90467-9  0.328
1984 Labrie F, Dupont A, Bélanger A, Lacoursière Y. Complete androgen blockade at start of treatment shows dramatic improvement of survival in prostate cancer Journal of Steroid Biochemistry. 20: 1378. DOI: 10.1016/0022-4731(84)90440-0  0.315
1983 Boissier JR, Euvrard C, Oberlander C, Laurent J, Dumont C, Labrie F. Comparative study of central dopaminergic properties of RU 29717 (N-propyl-9-oxaergoline) and pergolide. European Journal of Pharmacology. 87: 183-189. PMID 6857756 DOI: 10.1016/0014-2999(83)90328-X  0.339
1983 Bédard P, Boucher R, Paolo TD, Labrie F. Biphasic effect of estradiol and domperidone on lingual dyskinesia in monkeys Experimental Neurology. 82: 172-182. PMID 6628606 DOI: 10.1016/0014-4886(83)90252-2  0.324
1983 Labrie F, Gagné B, Lefèvre G, Meunier H. CRF stimulates adenylate cyclase activity in the intermediate lobe of the pituitary gland. Molecular and Cellular Endocrinology. 30: 347-351. PMID 6602723 DOI: 10.1016/0303-7207(83)90069-2  0.343
1983 Labrie F, Dupont A, Belanger A, Lacoursiere Y, Raynaud JP, Husson JM, Gareau J, Fazekas AT, Sandow J, Monfette G. New approach in the treatment of prostate cancer: Complete instead of partial withdrawal of androgens Prostate. 4: 579-594. PMID 6415630 DOI: 10.1002/Pros.2990040605  0.385
1983 Labrie F, Dupont A, Belanger A, Lefebvre FA, Cusan L, Monfette G, Laberge JG, Emond JP, raynaud JP, Husson JM, Fazekas ATA. New hormonal treatment in cancer of the prostate: Combined administration of an LHRH agonist and an antiandrogen Journal of Steroid Biochemistry. 19: 999-1007. PMID 6411995 DOI: 10.1016/0022-4731(83)90046-8  0.397
1983 Labrie F, Dupont A, Belanger A, Lefebvre FA, Cusan L, Raynaud JP, Husson JM, Fazekas ATA. New hormonal therapy in prostate cancer: Combined use of a pure antiandrogen and an LHRH agonist Hormone Research in Paediatrics. 18: 18-27. PMID 6411578 DOI: 10.1159/000179775  0.42
1983 Lemay A, Metha AE, Tolis G, Faure N, Labrie F, Fazekas AT. Gonadotropins and estradiol responses to single intranasal or subcutaneous administration of a luteinizing hormone-releasing hormone agonist in the early follicular phase. Fertility and Sterility. 39: 668-73. PMID 6404661 DOI: 10.1016/S0015-0282(16)47063-9  0.365
1983 Lemay A, Faure N, Labrie F, Fazekas ATA. Gonadotroph and corpus luteum responses to two successive intranasal doses of a luteinizing hormone-releasing hormone agonist at different days after the midcycle luteinizing hormone surge Fertility and Sterility. 39: 661-667. PMID 6404660 DOI: 10.1016/S0015-0282(16)47062-7  0.345
1983 Leung PCK, Raymond V, Labrie F. Stimulation of phosphatidic acid and phosphatidylinositol labeling in luteal cells by luteinizing hormone releasing hormone. Endocrinology. 112: 1138-1140. PMID 6337044 DOI: 10.1210/Endo-112-3-1138  0.375
1983 Proulx-Ferland L, Meunier H, Côté J, Dumont D, Gagné B, Labrie F. MULTIPLE FACTORS INVOLVED IN THE CONTROL OF ACTH AND α-MSH SECRETION Journal of Steroid Biochemistry. 19: 439-445. PMID 6310240 DOI: 10.1016/0022-4731(83)90201-7  0.371
1983 St-Arnaud R, Walker P, Kelly PA, Labrie F. Rat ovarian epidermal growth factor receptors: characterization and hormonal regulation. Molecular and Cellular Endocrinology. 31: 43-52. PMID 6309584 DOI: 10.1016/0303-7207(83)90029-1  0.364
1983 Giguère V, Labrie F. Additive effects of epinephrine and corticotropin-releasing factor (CRF) on adrenocorticotropin release in rat anterior pituitary cells. Biochemical and Biophysical Research Communications. 110: 456-462. PMID 6301454 DOI: 10.1016/0006-291X(83)91171-3  0.353
1983 Michel D, Lefèvre G, Labrie F. Interactions between growth hormone-releasing factor, prostaglandin E2 and somatostatin on cyclic AMP accumulation in rat adenohypophysial cells in culture. Molecular and Cellular Endocrinology. 33: 255-264. PMID 6140196 DOI: 10.1016/0303-7207(83)90171-5  0.361
1983 Labrie F, Gagné B, Lefèvre G. Growth hormone-releasing factor stimulates adenylate cyclase activity in the anterior pituitary gland. Life Sciences. 33: 2229-2233. PMID 6139729 DOI: 10.1016/0024-3205(83)90295-3  0.348
1983 Norstedt G, Mode A, Hökfelt T, Eneroth P, Elde R, Ferland L, Labrie F, Gustafsson JA. Possible role of somatostatin in the regulation of the sexually differentiated steroid metabolism and prolactin receptor in rat liver. Endocrinology. 112: 1076-90. PMID 6129964 DOI: 10.1210/Endo-112-3-1076  0.338
1983 Labrie F, Giguère V, Raymond V, Pelletier G, Veilleux R, Cote J, Antakly T. Anterior Pituitary Cells in Culture: A Precise Assay System for Hypothalamic and Peripheral Hormones Advances in Cell Biology. 4: 381-406. DOI: 10.1016/B978-0-12-008304-6.50018-X  0.385
1983 Labrie F, Proulx L, Veilleux R. 457 Specificity of the action of gestrinone at the hypothalamo-pituitary level in vitro and in vivo in the rat Journal of Steroid Biochemistry. 19: 156. DOI: 10.1016/0022-4731(83)91958-1  0.323
1983 St-Arnaud R, Kelly S, Dupont A, Belanger A, Labrie F. Second international congress of hormones and cancer442 Marked loss of LH bioactivity in men with cancer of the prostate treated with an LHRH agonist and an antiandrogen Journal of Steroid Biochemistry. 19: 147. DOI: 10.1016/0022-4731(83)91942-8  0.359
1983 Belanger A, Dupont A, Labrie F, Raynaud JP. 441 Inhibitory effect of combined administration of an lhrh agonist and an antiandrogen on adrenal androgens in patients with cancer of the prostate Journal of Steroid Biochemistry. 19: 147. DOI: 10.1016/0022-4731(83)91941-6  0.353
1983 Labrie F, Dupont A, Belanger A, Husson J, Raynaud J. 249 A new approach in the hormonal therapy of prostate cancer: Complete instead of partial neutralization of androgens Journal of Steroid Biochemistry. 19: 83. DOI: 10.1016/0022-4731(83)91749-1  0.344
1982 Paolo TD, Poyet P, Labrie F. Effect of prolactin and estradiol on rat striatal dopamine receptors. Life Sciences. 31: 2921-2929. PMID 7162358 DOI: 10.1016/0024-3205(82)90684-1  0.344
1982 Resko JA, Belanger A, Labrie F. Effects of chronic treatment with a potent luteinizing hormone releasing hormone agonist on serum luteinizing hormone and steroid levels in the male rhesus monkey. Biology of Reproduction. 26: 378-84. PMID 7044432 DOI: 10.1095/Biolreprod26.3.378  0.351
1982 Faure N, Labrie F, Belanger A, Lemay A, Raynaud JP, Ohe MVD, Fazekas ATA. Sensitivity of luteinizing hormone and gonadal steroid responses to single intranasal administration of an LHRH agonist (Hoe-766) in young normal adult men Journal of Endocrinological Investigation. 5: 355-360. PMID 6820372 DOI: 10.1007/Bf03350532  0.376
1982 Leung PCK, Raymond V, Labrie F. Mechanism of action of TRH: involvement of the phosphatidylinositol (PI) response in the action of TRH in rat anterior pituitary cells. Life Sciences. 31: 3037-3041. PMID 6819422 DOI: 10.1016/0024-3205(82)90072-8  0.329
1982 Faure N, Labrie F, Lemay A, Bélanger A, Gourdeau Y, Laroche B, Robert G. Inhibition of serum androgen levels by chronic intranasal and subcutaneous administration of a potent luteinizing hormone-releasing hormone (LH-RH) agonist in adult men. Fertility and Sterility. 37: 416-24. PMID 6800852 DOI: 10.1016/S0015-0282(16)46107-8  0.414
1982 Lemay A, Faure N, Labrie F. Sensitivity of pituitary and corpus luteum responses to single intranasal administration of (D-Ser[TBU]6-des-Gly-NH210) luteinizing hormone-releasing hormone ethylamide (Buserelin) in normal women Fertility and Sterility. 37: 193-200. PMID 6800846 DOI: 10.1016/S0015-0282(16)46038-3  0.359
1982 Tolis G, Ackman D, Stellos A, Mehta A, Labrie F, Fazekas AT, Comaru-Schally AM, Schally AV. Tumor growth inhibition in patients with prostatic carcinoma treated with luteinizing hormone-releasing hormone agonists. Proceedings of the National Academy of Sciences of the United States of America. 79: 1658-62. PMID 6461861 DOI: 10.1073/Pnas.79.5.1658  0.376
1982 Meunier H, Labrie F. Beta-adrenergic, CRF-ergic and dopaminergic mechanisms controlling α-MSH secretion in rat pars intermedia cells in primary culture Progress in Neuro-Psychopharmacology & Biological Psychiatry. 6: 411-415. PMID 6298887 DOI: 10.1016/S0278-5846(82)80118-8  0.347
1982 Meunier H, Lefèvre G, Dumont D, Labrie F. CRF stimulates α-MSH secretion and cyclic AMP accumulation in rat pars intermedia cells Life Sciences. 31: 2129-2135. PMID 6294429 DOI: 10.1016/0024-3205(82)90105-9  0.341
1982 Séguin C, Pelletier G, Dubé D, Labrie F. Distribution of luteinizing hormone-releasing hormone receptors in the rat ovary. Regulatory Peptides. 4: 183-190. PMID 6293004 DOI: 10.1016/0167-0115(82)90110-0  0.383
1982 Labrie F, Gagné B, Lefèvre G. Corticotropin-releasing factor stimulates adenylate cyclase activity in the anterior pituitary gland Life Sciences. 31: 1117-1121. PMID 6292603 DOI: 10.1016/0024-3205(82)90085-6  0.332
1982 Giguere V, Labrie F. Vasopressin potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture. Endocrinology. 111: 1752-4. PMID 6290198 DOI: 10.1210/Endo-111-5-1752  0.333
1982 Meunier H, Labrie F. Specificity of the β2-adrenergic receptor stimulating cyclic AMP accumulation in the intermediate lobe of rat pituitary gland European Journal of Pharmacology. 81: 411-420. PMID 6288411 DOI: 10.1016/0014-2999(82)90106-6  0.32
1982 Marchett B, Labrie F. Prolactin inhibits pituitary luteinizing hormone-releasing hormone receptors in the rat. Endocrinology. 111: 1209-1216. PMID 6288351 DOI: 10.1210/Endo-111-4-1209  0.374
1982 Marchetti B, Reeves JJ, Pelletier G, Labrie F. Modulation of pituitary luteinizing hormone releasing hormone receptors by sex steroids and luteinizing hormone releasing hormone in the rat. Biology of Reproduction. 27: 133-45. PMID 6288128 DOI: 10.1095/Biolreprod27.1.133  0.367
1982 Giguère V, Labrie F, Côté J, Coy DH, Sueiras-Diaz J, Schally AV. Stimulation of cyclic AMP accumulation and corticotropin release by synthetic ovine corticotropin-releasing factor in rat anterior pituitary cells: site of glucocorticoid action. Proceedings of the National Academy of Sciences of the United States of America. 79: 3466-9. PMID 6285350 DOI: 10.1073/Pnas.79.11.3466  0.337
1982 Proulx-Ferland L, Labrie F, Dumont D, Cote J, Coy DH, Sveiraf J. Corticotropin-releasing factor stimulates secretion of melanocyte-stimulating hormone from the rat pituitary Science. 217: 62-63. PMID 6283632 DOI: 10.1126/Science.6283632  0.356
1982 Labrie F, Veilleux R, Lefevre G, Coy DH, Sueiras-Diaz J, Schally AV. Corticotropin-releasing factor stimulates accumulation of adenosine 3', 5'-monophosphate in rat pituitary corticotrophs. Science (New York, N.Y.). 216: 1007-8. PMID 6281886 DOI: 10.1126/Science.6281886  0.318
1982 Giguère V, Côté J, Labrie F. Specific Inhibition by Glucocorticoids of the α1-Adrenergic Stimulation of Adrenocorticotropin Release in Rat Anterior Pituitary Cells Endocrinology. 110: 1225-1230. PMID 6277597 DOI: 10.1210/Endo-110-4-1225  0.344
1982 Giguère V, Meunier H, Veilleux R, Labrie F. Direct effects of sex steroids on prolactin release at the anterior pituitary level: interactions with dopamine, thyrotropin-releasing hormone, and isobutylmethylxanthine. Endocrinology. 111: 857-862. PMID 6179767 DOI: 10.1210/Endo-111-3-857  0.33
1982 Meunier H, Labrie F. The dopamine receptor in the intermediate lobe of the rat pituitary gland is negatively coupled to adenylate cyclase Life Sciences. 30: 963-968. PMID 6122149 DOI: 10.1016/0024-3205(82)90625-7  0.321
1981 Lagace L, Labrie F, Antakly T, Pelletier G. Sensitivity of rat adenohypophyseal cells to estradiol and LHRH during long-term culture. American Journal of Physiology-Endocrinology and Metabolism. 240. PMID 6787927 DOI: 10.1152/Ajpendo.1981.240.6.E602  0.369
1981 Drouin J, Labrie F. Interactions between 17 beta-estradiol and progesterone in the control of luteinizing hormone and follicle-stimulating hormone release in rat anterior pituitary cells in culture. Endocrinology. 108: 52-7. PMID 6780315 DOI: 10.1210/Endo-108-1-52  0.359
1981 Séguin C, Bélanger A, Cusan L, Pelletier G, Reeves JJ, Lefebvre FA, Kelly PA, Labrie F. Relative importance of the adenohypophyseal and gonadal sites in inhibitory action of LHRH agonists. Biology of Reproduction. 24: 889-901. PMID 6264984 DOI: 10.1095/Biolreprod24.4.889  0.384
1981 Ferland L, Marchetti B, Seguin C, Lefebvre FA, Reeves JJ, Labrie F. Dissociated changes of pituitary luteinizing hormone-releasing hormone (LHRH) receptors and responsiveness to the neurohormones induced by 17β-estradiol and LHRH in vivo in the rat Endocrinology. 109: 87-93. PMID 6263596 DOI: 10.1210/Endo-109-1-87  0.394
1981 Massicotte J, Borgus J, Lachance R, Labrie F. Inhibition of HCG-induced cyclic AMP accumulation and steroidogenesis in rat luteal cells by an LHRH agonist. Journal of Steroid Biochemistry. 14: 239-242. PMID 6261040 DOI: 10.1016/0022-4731(81)90131-X  0.37
1981 Denizeau F, Dubé D, Antakly T, Lemay A, Parent A, Pelletier G, Labrie F. Attempts to demonstrate peptide localization and secretion in primary cell cultures of fetal rat hypothalamus. Neuroendocrinology. 32: 96-102. PMID 6259548 DOI: 10.1159/000123138  0.331
1981 Séguin C, Cusan L, Belanger A, Kelly PA, Labrie F, Raynaud J. Additive inhibitory effects of treatment with an LHRH agonist and an antiandrogen on androgen-dependent issues in the rat Molecular and Cellular Endocrinology. 21: 37-41. PMID 6259002 DOI: 10.1016/0303-7207(81)90028-9  0.377
1981 Giguere V, Lefebvre F, Labrie F. Androgens Decrease Lhrh Binding Sites In Rat Anterior Pituitary Cells In Culture Endocrinology. 108: 350-352. PMID 6257490 DOI: 10.1210/Endo-108-1-350  0.368
1981 Carmichael R, Bélanger A, Cusan L, Séguin C, Caron S, Labrie F. Increased testicular 5 alpha-androstane-3 alpha, 17 beta-diol formation induced by treatment with [D-Ser (TBU) 6, des-Gly-NH2(10)] LHRH ethylamide in the rat. Steroids. 36: 383-91. PMID 6255633 DOI: 10.1016/0039-128X(80)90027-6  0.312
1981 Giguere V, Cote J, Labrie F. Characteristics of the α-Adrenergic Stimulation of Adrenocorticotropin Secretion in Rat Anterior Pituitary Cells Endocrinology. 109: 757-762. PMID 6114856 DOI: 10.1210/Endo-109-3-757  0.357
1981 Raymond V, Lépine J, Giguère V, Lissitzky J, Côté J, Labrie F. Parallel stimulation of ACTH, β-LPH + β-endorphin and α-MSH release by α-adrenergic agents in rat anterior pituitary cells in culture Molecular and Cellular Endocrinology. 22: 295-303. PMID 6114000 DOI: 10.1016/0303-7207(81)90038-1  0.326
1981 Bélanger A, Auclair C, Séguin C, Caron S, Labrie F. Prolactin Stimulation of Testicular Steroid Biosynthesis in the Male Rat Journal of Andrology. 2: 80-86. DOI: 10.1002/J.1939-4640.1981.Tb00599.X  0.395
1980 Labrie F, Ferland L, Denizeau F, Beaulieu M. Sex steroids interact with dopamine at the hypothalamic and pituitary levels to modulate prolactin secretion. Journal of Steroid Biochemistry. 12: 323-30. PMID 7421220 DOI: 10.1016/0022-4731(80)90287-3  0.367
1980 Raynaud JP, Bouton MM, Moguilewsky M, Ojasoo T, Philibert D, Beck G, Labrie F, Mornon JP. Steroid hormone receptors and pharmacology Journal of Steroid Biochemistry. 12: 143-157. PMID 7421203 DOI: 10.1016/0022-4731(80)90264-2  0.336
1980 Euvrard C, Ferland L, Paolo TD, Beaulieu M, Labrie F, Oberlander C, Raynaud JP, Boissier JR. Activity of two new potent dopaminergic agonists at the striatal and anterior pituitary levels Neuropharmacology. 19: 379-386. PMID 7383283 DOI: 10.1016/0028-3908(80)90190-2  0.329
1980 Lagace L, Massicotte J, Labrie F. Acute Stimulatory Effects of Progesterone on Luteinizing Hormone and Follicle-Stimulating Hormone Release in Rat Anterior Pituitary Cells in Culture Endocrinology. 106: 684-689. PMID 7353537 DOI: 10.1210/Endo-106-3-684  0.354
1980 Faure N, Labrie F, Olivier G, Tremblay M, Cloutier D, Lemay A, Ferland L, Azadian-Boulanger G, Bouton MM, Husson JM, Raynaud JP. Effects of RU16117, an orally active weak oestrogenic compound, in postmenopausal women Maturitas. 2: 155-168. PMID 6782429 DOI: 10.1016/0378-5122(80)90050-X  0.305
1980 Raynaud J, Mary I, Moguilewsky M, Mouren M, Labrie F. Inhibition of Progesterone Secretion During the Luteal Phase by Two Luteinizing Hormone-Releasing Hormone Agonists in Macaca fascicularis Fertility and Sterility. 34: 593-598. PMID 6778718 DOI: 10.1016/S0015-0282(16)45201-5  0.348
1980 Lefebvre FA, Reeves JJ, Seguin C, Massicotte J, Labrie F. Specific binding of a potent LHRH agonist in rat testis Molecular and Cellular Endocrinology. 20: 127-134. PMID 6777213 DOI: 10.1016/0303-7207(80)90076-3  0.313
1980 Bélanger A, Labrie F, Lemay A, Caron S, Raynaud JP. Inhibitory effects of a single intranasal administration of [d-Ser(TBU)6, des-Gly-NH210]LHRK ethylamide, a potent LHRK agonist, on serum steroid levels in normal adult men Journal of Steroid Biochemistry. 13: 123-126. PMID 6770199 DOI: 10.1016/0022-4731(80)90182-X  0.347
1980 Kelly PA, Seguin C, Cusan L, Labrie F. Stimulatory effect of luteinizing hormone and human chorionic gonadotropin on testicular prolactin receptor levels Biology of Reproduction. 23: 924-928. PMID 6258656 DOI: 10.1095/Biolreprod23.5.924  0.375
1980 Reeves JJ, Seguin C, Lefebvre FA, Kelly PA, Labrie F. Similar luteinizing hormone-releasing hormone binding sites in rat anterior pituitary and ovary Proceedings of the National Academy of Sciences of the United States of America. 77: 5567-5571. PMID 6254091 DOI: 10.1073/Pnas.77.9.5567  0.373
1980 Massicotte J, Veilleux R, Lavoie M, Labrie F. An LHRH agonist inhibits FSH-induced cyclic AMP accumulation and steroidogenesis in porcine granulosa cells in culture. Biochemical and Biophysical Research Communications. 94: 1362-1366. PMID 6249310 DOI: 10.1016/0006-291X(80)90569-0  0.353
1980 Cusan L, Bélanger A, Séguin C, Labrie F. Impairment of pituitary and gonadal functions in alloxan-induced diabetic male rats. Molecular and Cellular Endocrinology. 18: 165-76. PMID 6248397 DOI: 10.1016/0303-7207(80)90063-5  0.347
1980 Belanger A, Auclair C, Ferland L, Caron S, Labrie F. Time-course of the effect of treatment with a potent LHRH agonist on testicular steroidogenesis and gonadotropin receptor levels in the adult rat. Journal of Steroid Biochemistry. 13: 191-6. PMID 6247573 DOI: 10.1016/0022-4731(80)90191-0  0.382
1980 LABRIE F, BÉLANGER A, CUSAN L, SEGUIN C, PELLETIER G, KELLY PA, REEVES JJ, LEFEBVRE F, LEMAY A, GOURDEAU Y, RAYNAUD J. Antifertility Effects of LHRH Agonists in the Male Journal of Andrology. 1: 209-228. DOI: 10.1002/J.1939-4640.1980.Tb00034.X  0.414
1980 Pelletier G, Cusan GL, Bélanger A, Séguin C, Kelly PA, Labrie F. Further Studies on the Inhibitory Effect of [D‐A1a6, des‐Gly‐NH210]LHRH Ethylamide on Spermatogenesis and Steroidogenesis in the Rat: Reversibility and Effect of Androgen Administration Journal of Andrology. 1: 171-181. DOI: 10.1002/J.1939-4640.1980.Tb00029.X  0.376
1979 Antakly T, Pelletier G, Zeytinoglu F, Labrie F. Effects of colchicine on the morphology and prolactin secretion of rat anterior pituitary cells in monolayer culture. American Journal of Anatomy. 156: 353-371. PMID 532790 DOI: 10.1002/Aja.1001560306  0.325
1979 Ferland L, Labrie F, Euvrard C, Raynaud J. Antidopaminergic activity of estrogens on prolactin release at the pituitary level in vivo. Molecular and Cellular Endocrinology. 14: 199-204. PMID 467781 DOI: 10.1016/0303-7207(79)90045-5  0.383
1979 Lemay A, Labrie F, Belanger A, Raynaud JP. Luteolytic effect of intranasal administration of [D-Ser(TBU)6,des-Gly-NH210]-luteinizing hormone-releasing hormone ethylamide in normal women Fertility and Sterility. 32: 646-651. PMID 389676 DOI: 10.1016/S0015-0282(16)44412-2  0.359
1979 Raynaud JP, Bonne C, Bouton MM, Lagace L, Labrie F. Action of a non-steroid anti-androgen, RU 23908, in peripheral and central tissues. Journal of Steroid Biochemistry. 11: 93-9. PMID 385986 DOI: 10.1016/0022-4731(79)90281-4  0.398
1979 Lagacé L, Labrie F, Lorenzen J, Schwartz NB, Channing CP. Selective inhibitory effect of porcine follicular fluid on follicle stimulating hormone secretion in anterior pituitary cells in culture. Clinical Endocrinology. 10: 401-405. PMID 383315 DOI: 10.1111/J.1365-2265.1979.Tb02095.X  0.353
1979 Lemay A, Labrie F, Ferland L, Raynaud JP. Possible luteolytic effects of luteinizing hormone-releasing hormone in normal women Fertility and Sterility. 31: 29-34. PMID 369890 DOI: 10.1016/S0015-0282(16)43755-6  0.32
1979 Kelly PA, Asselin J, Turcot-Lemay L, Labrie F, Raynaud JP. Effects of progesterone and R2323 on the development of dimethylbenzanthracene-induced mammary tumors European Journal of Cancer (1965). 15: 1243-1251. PMID 230056 DOI: 10.1016/0014-2964(79)90250-0  0.312
1979 Raymond V, Lépine J, Lissitzky J, Côté J, Labrie F. Parallel release of ACTH, β-endorphdm, α-MSH and β-MSH-like immunoreactivities in rat anterior pituitary cells in culture Molecular and Cellular Endocrinology. 16: 113-122. PMID 229047 DOI: 10.1016/0303-7207(79)90109-6  0.304
1979 Antakly T, Zeytinoglu F, Pelletier G, Labrie F. Autohistoradiographic localization of thyrotropin-releasing hormone (TRH)-binding sites in cultured rat pituitary cells. Experimental Cell Research. 122: 394-399. PMID 228951 DOI: 10.1016/0014-4827(79)90317-3  0.332
1979 Labrie F, Auclair C, Cusan L, Lemay A, Bélanger A, Kelly PA, Ferland L, Azadian-Boulanger G, Raynaud JP. Inhibitory effects of treatment with LHRH or its agonists on ovarian receptor levels and function. Advances in Experimental Medicine and Biology. 112: 687-93. PMID 223405 DOI: 10.1007/978-1-4684-3474-3_75  0.414
1979 Cusan L, Auclair C, Belanger A, Ferland L, Kelly PA, Seguin C, Labrie F. Inhibitory effects of long term treatment with a luteinizing hormone-releasing hormone agonist on the pituitary-gonadal axis in male and female rats. Endocrinology. 104: 1369-76. PMID 220032 DOI: 10.1210/Endo-104-5-1369  0.38
1979 Labrie F, Borgeat P, Drouin J, Beaulieu M, Lagacé L, Ferland L, Raymond V. Mechanism of action of hypothalamic hormones in the adenohypophysis. Annual Review of Physiology. 41: 555-69. PMID 219766 DOI: 10.1146/Annurev.Ph.41.030179.003011  0.392
1979 Labrie F, Drouin J, Ferland L, Lagacé L, Beaulieu M, De Léan A, Kelly PA, Caron MG, Raymond V. Mechanism of action of hypothalamic hormones in the anterior pituitary gland and specific modulation of their activity by sex steroids and thyroid hormones. Recent Progress in Hormone Research. 34: 25-93. PMID 216056 DOI: 10.1016/B978-0-12-571134-0.50006-5  0.372
1979 Paolo TD, Carmichael R, Labrie F, Raynaud J. Effects of estrogens on the characteristics of [3H]spiroperidol and [3H]RU24213 binding in rat anterior pituitary gland and brain Molecular and Cellular Endocrinology. 16: 99-112. PMID 116893 DOI: 10.1016/0303-7207(79)90108-4  0.332
1979 Labrie F, Godbout M, Beaulieu M, Borgeat P, Barden N. Mechanism of action of hypothalamic hormones in the anterior pituitary Trends in Biochemical Sciences. 4: 158-160. DOI: 10.1016/0968-0004(79)90005-7  0.365
1978 Ferland L, Kledzik GS, Cusan L, Labrie F. Evidence for a role of endorphins in stress- and suckling-induced prolactin release in the rat Molecular and Cellular Endocrinology. 12: 267-272. PMID 738523 DOI: 10.1016/0303-7207(78)90085-0  0.315
1978 Dupont A, Alvarado-Urbina G, Côté J, Labrie F. Enzymatic degradation of somatostatin by rat plasma and hypothalamus. Canadian Journal of Physiology and Pharmacology. 56: 840-843. PMID 709424 DOI: 10.1139/Y78-132  0.32
1978 Raymond V, Beaulieu M, Labrie F, Boissier J. Potent antidopaminergic activity of estradiol at the pituitary level on prolactin release Science. 200: 1173-1175. PMID 418505 DOI: 10.1126/Science.418505  0.36
1978 Ferland L, Labrie F, Kelly PA, Raynaud JP. Inhibitory effects of RU 16117, a potent estrogen antagonist, on the estrous cycle in the rat Biology of Reproduction. 18: 99-104. PMID 342001 DOI: 10.1095/Biolreprod18.1.99  0.351
1978 Drouin J, Lavoie M, Labrie F. Effect of gonadal steroids on the luteinizing hormone and follicle- stimulating hormone response to 8-bromo-adenosine 3',5'-monophosphate in anterior pituitary cells in culture Endocrinology. 102: 358-361. PMID 217589 DOI: 10.1210/Endo-102-2-358  0.354
1978 Kledzik GS, Cusan L, Auclair C, Kelly PA, Labrie F. Inhibition of ovarian luteinizing hormone (LH) and follicle-stimulating hormone receptor levels with an LH-releasing hormone agonist during the estrous cycle in the rat. Fertility and Sterility. 30: 348-353. PMID 213320 DOI: 10.1016/S0015-0282(16)43524-7  0.393
1978 Kledzik GS, Cusan L, Auclair C, Kelly PA, Labrie F. Inhibitory Effect of a Luteinizing Hormone (LH)-Releasing Hormone Agonist on Rat Ovarian LH and Follicle-Stimulating Hormone Receptor Levels During Pregnancy Fertility and Sterility. 29: 560-564. PMID 208873 DOI: 10.1016/S0015-0282(16)43286-3  0.379
1978 Auclair C, Kelly PA, Coy DH, Schally AV, Labrie F. Potent inhibitory activity of [D-Leu6, Des-Gly-NH2(10)]LHRH ethylamide on LH/hCG and PRL testicular receptor levels in the rat. Endocrinology. 101: 1890-3. PMID 201452 DOI: 10.1210/Endo-101-6-1890  0.375
1978 Asselin J, Labrie F. Effects of estradiol and prolactin on steroid receptor levels in 7,12-dimethylbenz(a)anthracene-induced mammary tumors and uterus in the rat Journal of Steroid Biochemistry. 9: 1079-1082. PMID 106188 DOI: 10.1016/0022-4731(78)90035-3  0.397
1978 Labrie F, Auclair C, Cusan L, Kelly PA, Pelletier G, Ferland L. Inhibitory Effect of LHRH and Its Agonists on Testicular Gonadotrophin Receptors and Spermatogenesis in the Rat International Journal of Andrology. 1: 303-318. DOI: 10.1111/J.1365-2605.1978.Tb00024.X  0.39
1978 Labrie F, Lagacé L, Ferland L, Kelly PA, Drouin J, Massicotte J, Bonne C, Raynaud J, Dorrington JH. Interactions Between LHRH, Sex Steroids and "Inhibin" in the Control of LH and FSH Secretion International Journal of Andrology. 1: 81-101. DOI: 10.1111/J.1365-2605.1978.Tb00008.X  0.394
1977 Cusan L, Dupont A, Kledzik GS, Labrie F, Coy DH, Schally AV. Potent prolactin and growth hormone releasing activity of more analogues of Met-enkephalin Nature. 268: 544-547. PMID 887172 DOI: 10.1038/268544A0  0.337
1977 Dupont A, Cusan L, Labrie F, Coy DH, Li CH. Stimulation of prolactin release in the rat by intraventricular injection of β-end orphin and methionine-enkephalin Biochemical and Biophysical Research Communications. 75: 76-82. PMID 849311 DOI: 10.1016/0006-291X(77)91291-8  0.342
1977 Drouin J, Lagacé L, Labrie F. Estradiol-induced increase of the LH responsive to LH releasing hormone (LHRH) in rat anterior pituitary cells in culture. Endocrinology. 99: 1477-81. PMID 793837 DOI: 10.1210/Endo-99-6-1477  0.365
1977 Kelly PA, LeBlanc G, Ferland L, Labrie F, Léan AD. Androgen inhibition of basal and estrogen-stimulated prolactin binding in rat liver. Molecular and Cellular Endocrinology. 9: 195-204. PMID 598616 DOI: 10.1016/0303-7207(77)90120-4  0.333
1977 Lean AD, Labrie F. Sensitizing effect of treatment with estrogens on TSH response to TRH in male rats. American Journal of Physiology-Endocrinology and Metabolism. 233. PMID 410310 DOI: 10.1152/Ajpendo.1977.233.3.E235  0.379
1977 Kelly PA, Asselin J, Caron MG, Labrie F, Raynaud JP. Potent inhibitory effect of a new antiestrogen (Ru 16117) on the growth of 7, 12-dimethylbenz[a]anthracene-lnduced rat mammary tumors Journal of the National Cancer Institute. 58: 623-628. PMID 402479 DOI: 10.1093/Jnci/58.3.623  0.332
1977 Pelletier G, Leclerc R, Labrie F, Cote J, Chretien M, Lis M. Immunohistochemical Localization of β-Lipotropic Hormone in the Pituitary Gland Endocrinology. 100: 770-776. PMID 401361 DOI: 10.1210/Endo-100-3-770  0.311
1977 Dussault JH, Walker P, Dubois JD, Labrie F. The development of the hypothalamo-pituitary axis in the neonatal rat: sexual maturation in male and female rats as assessed by hypothalamic LHRH and pituitary and serum LH and FSH concentrations Canadian Journal of Physiology and Pharmacology. 55: 1091-1097. PMID 336164 DOI: 10.1139/Y77-149  0.326
1977 Dupont A, Cusan L, Garon M, Labrie F, Li CH. Beta-endorphin: stimulation of growth hormone release in vivo. Proceedings of the National Academy of Sciences of the United States of America. 74: 358-359. PMID 264687 DOI: 10.1073/Pnas.74.1.358  0.354
1977 Auclair C, Kelly PA, Labrie F, Coy DH, Schally AV. Inhibition of testicular luteinizing hormone receptor level by treatment with a potent luteinizing hormone-releasing hormone agonist of human chorionic gonadotropin. Biochemical and Biophysical Research Communications. 76: 855-62. PMID 197929 DOI: 10.1016/0006-291X(77)91579-0  0.403
1977 Labrie F, Drouin J, De Léan A, Lagacé L, Ferland L, Beaulieu M. Mechanism of action of luteinizing hormone releasing hormone and thyrotropin releasing hormone in the anterior pituitary gland and modulation of their activity by peripheral hormones. Advances in Experimental Medicine and Biology. 87: 157-79. PMID 197831 DOI: 10.1007/978-1-4615-8849-8_8  0.355
1977 Asselin J, Kelly PA, Caron MG, Labrie F. Control of hormone receptor levels and growth of 7,12-dimethylbenz(a)anthracene-induced mammary tumors by estrogens, progesterone and prolactin Endocrinology. 101: 666-671. PMID 196828 DOI: 10.1210/Endo-101-3-666  0.327
1977 Léan AD, Garon M, Kelly PA, Labrie F. Changes of Pituitary Thyrotropin Releasing Hormone (TRH) Receptor Level and Prolactin Response to TRH During the Rat Estrous Cycle Endocrinology. 100: 1505-1510. PMID 192538 DOI: 10.1210/Endo-100-6-1505  0.346
1977 Léan AD, Ferland L, Drouin J, Kelly PA, Labrie F. Modulation of pituitary thyrotropin releasing hormone receptor levels by estrogens and thyroid hormones. Endocrinology. 100: 1496-504. PMID 192537 DOI: 10.1210/Endo-100-6-1496  0.382
1977 Labrie F, Ferland L, Lagace L, Drouin J, Asselin J, Azadian-Boulanger G, Raynaud JP. High inhibitory activity of R 5020, a pure progestin, at the hypothalamic-adenohypophyseal level on gonadotropin secretion Fertility and Sterility. 28: 1104-1112. PMID 71251 DOI: 10.1016/S0015-0282(16)42864-5  0.395
1977 Labrie F, Lagace L, Drouin J, Raymond V. Specific control of LH and FSH secretion by estrogens, androgens and progestins at the anterior pituitary level Journal of Steroid Biochemistry. 8: vi. DOI: 10.1016/0022-4731(77)90126-1  0.378
1976 Labrie F, Kelly PA, Asselin J, Raynaud JP. Potent inhibitory activity of a new antiestrogen, RU 16117, on the development and growth of DMBA induced rat mammary adenocarcinoma Recent Results in Cancer Research. 109-120. PMID 827798 DOI: 10.1007/978-3-642-81043-5_10  0.356
1976 Drouin J, Labrie F. Specificity of the stimulatory effect of prostaglandins on hormone release in rat anterior pituitary cells in culture. Prostaglandins. 11: 355-65. PMID 817370 DOI: 10.1016/0090-6980(76)90157-X  0.337
1976 Drouin J, De Léan A, Rainville D, Lachance R, Labrie F. Characteristics of the interaction between thyrotropin-releasing hormone and somatostatin for thyrotropin and prolactin release. Endocrinology. 98: 514-21. PMID 813994 DOI: 10.1210/Endo-98-2-514  0.347
1976 Pelletier G, Leclerc R, Labrie F. Identification of gonadotropic cells in the human pituitary by immunoperoxidase technique Molecular and Cellular Endocrinology. 6: 123-128. PMID 793912 DOI: 10.1016/0303-7207(76)90012-5  0.346
1976 Coy DH, Labrie F, Savary M, Coy EJ, Schally AV. Antagonistic activity of analogs of luteinizing hormone-releasing hormone (LH-RH) in vitro. Molecular and Cellular Endocrinology. 5: 201-8. PMID 782958 DOI: 10.1016/0303-7207(76)90083-6  0.302
1976 Drouin J, Ferland L, Bernard J, Labrie F. Site of the in vivo stimulatory effect of prostaglandins on LH release. Prostaglandins. 11: 367-75. PMID 772758 DOI: 10.1016/0090-6980(76)90158-1  0.368
1976 Asselin J, Labrie F, Gourdeau Y, Bonne C, Raynaud JP. Binding of [3H] methyltrienolone (R 1881) in rat prostate and human benign prostatic hypertrophy (BPH). Steroids. 28: 449-59. PMID 64005 DOI: 10.1016/0039-128X(76)90014-3  0.334
1975 Dupont A, Labrie F, Pelletier G, Puviani R, Coy DH, Coy EJ, Schally AV. Organ distribution of radioactivity and disappearance of radioactivity from plasma after administration of (3H) luteinizing hormone-releasing hormone to mice and rats. Neuroendocrinology. 16: 65-73. PMID 4610444 DOI: 10.1159/000122553  0.319
1975 Belanger A, Labrie F, Borgeat P, Savary M, Cote J, Drouin J, Schally AV, Coy DH, Coy EJ, Sestanj K, Nelson V, Gotz M, Immer H. Inhibition of growth hormone and thyrotropin release by growth hormone-release inhibiting hormone. Molecular and Cellular Endocrinology. 1: 329-39. PMID 4375636 DOI: 10.1016/0303-7207(74)90022-7  0.343
1975 Dupont A, Labrie F, Levasseur L, Schally AV. Characteristics of the plasma disappearance of (3H)-thyrotropin-releasing hormone in the rat. Canadian Journal of Physiology and Pharmacology. 52: 1012-9. PMID 4214597 DOI: 10.1139/Y74-132  0.308
1975 Dupont A, Kastin AJ, Labrie F, Pelletier G, Puviani R, Schally AV. Distribution of radioactivity in the organs of the rat and mouse after injection of (125I)alpha-melanocyte-stimulating hormone. The Journal of Endocrinology. 64: 237-41. PMID 1117233 DOI: 10.1677/Joe.0.0640237  0.304
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