Paula M. Vertino - Publications

Affiliations: 
Emory University, Atlanta, GA 
Area:
Genetics, Molecular Biology

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bell JS, Kagey JD, Barwick BG, Dwivedi B, McCabe MT, Kowalski J, Vertino PM. Factors affecting the Persistence of Drug-induced Reprogramming of the Cancer Methylome. Epigenetics. 0. PMID 27082926 DOI: 10.1080/15592294.2016.1158364  0.8
2015 Farkas AE, Hilgarth RS, Capaldo CT, Gerner-Smidt C, Powell DR, Vertino PM, Koval M, Parkos CA, Nusrat A. HNF4α regulates claudin-7 protein expression during intestinal epithelial differentiation. The American Journal of Pathology. 185: 2206-18. PMID 26216285 DOI: 10.1016/j.ajpath.2015.04.023  0.56
2015 Stoyanov E, Ludwig G, Mizrahi L, Olam D, Schnitzer-Perlman T, Tasika E, Sass G, Tiegs G, Jiang Y, Nie T, Kohler J, Schinazi RF, Vertino PM, Cedar H, Galun E, et al. Chronic liver inflammation modifies DNA methylation at the precancerous stage of murine hepatocarcinogenesis. Oncotarget. 6: 11047-60. PMID 25918251  0.56
2014 Yang R, Chen L, Newman S, Gandhi K, Doho G, Moreno CS, Vertino PM, Bernal-Mizarchi L, Lonial S, Boise LH, Rossi M, Kowalski J, Qin ZS. Integrated analysis of whole-genome paired-end and mate-pair sequencing data for identifying genomic structural variations in multiple myeloma. Cancer Informatics. 13: 49-53. PMID 25288879 DOI: 10.4137/CIN.S13783  0.56
2014 Brodie SA, Lombardo C, Li G, Kowalski J, Gandhi K, You S, Khuri FR, Marcus A, Vertino PM, Brandes JC. Aberrant promoter methylation of caveolin-1 is associated with favorable response to taxane-platinum combination chemotherapy in advanced NSCLC. Plos One. 9: e107124. PMID 25222296 DOI: 10.1371/journal.pone.0107124  0.56
2014 Lin Y, Cradick TJ, Brown MT, Deshmukh H, Ranjan P, Sarode N, Wile BM, Vertino PM, Stewart FJ, Bao G. CRISPR/Cas9 systems have off-target activity with insertions or deletions between target DNA and guide RNA sequences. Nucleic Acids Research. 42: 7473-85. PMID 24838573 DOI: 10.1093/nar/gku402  0.56
2014 Smith AK, Conneely KN, Pace TW, Mister D, Felger JC, Kilaru V, Akel MJ, Vertino PM, Miller AH, Torres MA. Epigenetic changes associated with inflammation in breast cancer patients treated with chemotherapy. Brain, Behavior, and Immunity. 38: 227-36. PMID 24583204 DOI: 10.1016/j.bbi.2014.02.010  0.56
2014 Kapoor-Vazirani P, Vertino PM. A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing. The Journal of Biological Chemistry. 289: 7425-37. PMID 24459145 DOI: 10.1074/jbc.M113.520783  0.8
2014 Brodie SA, Li G, El-Kommos A, Kang H, Ramalingam SS, Behera M, Gandhi K, Kowalski J, Sica GL, Khuri FR, Vertino PM, Brandes JC. Class I HDACs are mediators of smoke carcinogen-induced stabilization of DNMT1 and serve as promising targets for chemoprevention of lung cancer. Cancer Prevention Research (Philadelphia, Pa.). 7: 351-61. PMID 24441677 DOI: 10.1158/1940-6207.CAPR-13-0254  0.56
2013 Yang Z, Garcia A, Xu S, Powell DR, Vertino PM, Singh S, Marcus AI. Withania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transition. Plos One. 8: e75069. PMID 24069380 DOI: 10.1371/journal.pone.0075069  0.56
2013 Zhou W, Marcus AI, Vertino PM. Dysregulation of mTOR activity through LKB1 inactivation. Chinese Journal of Cancer. 32: 427-33. PMID 23668926 DOI: 10.5732/cjc.013.10086  0.56
2012 Duncan CG, Barwick BG, Jin G, Rago C, Kapoor-Vazirani P, Powell DR, Chi JT, Bigner DD, Vertino PM, Yan H. A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation. Genome Research. 22: 2339-55. PMID 22899282 DOI: 10.1101/gr.132738.111  0.56
2012 Hashimoto H, Liu Y, Upadhyay AK, Chang Y, Howerton SB, Vertino PM, Zhang X, Cheng X. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Research. 40: 4841-9. PMID 22362737 DOI: 10.1093/nar/gks155  0.56
2011 Thaiparambil JT, Bender L, Ganesh T, Kline E, Patel P, Liu Y, Tighiouart M, Vertino PM, Harvey RD, Garcia A, Marcus AI. Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. International Journal of Cancer. Journal International Du Cancer. 129: 2744-55. PMID 21538350 DOI: 10.1002/ijc.25938  0.56
2011 Kapoor-Vazirani P, Kagey JD, Vertino PM. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation. Molecular and Cellular Biology. 31: 1594-609. PMID 21321083 DOI: 10.1128/MCB.00524-10  0.8
2010 Iskow RC, McCabe MT, Mills RE, Torene S, Pittard WS, Neuwald AF, Van Meir EG, Vertino PM, Devine SE. Natural mutagenesis of human genomes by endogenous retrotransposons. Cell. 141: 1253-61. PMID 20603005 DOI: 10.1016/j.cell.2010.05.020  0.56
2010 Kagey JD, Kapoor-Vazirani P, McCabe MT, Powell DR, Vertino PM. Long-term stability of demethylation after transient exposure to 5-aza-2'-deoxycytidine correlates with sustained RNA polymerase II occupancy. Molecular Cancer Research : McR. 8: 1048-59. PMID 20587535 DOI: 10.1158/1541-7786.MCR-10-0189  0.8
2010 Lund MJ, Butler EN, Hair BY, Ward KC, Andrews JH, Oprea-Ilies G, Bayakly AR, O'Regan RM, Vertino PM, Eley JW. Age/race differences in HER2 testing and in incidence rates for breast cancer triple subtypes: a population-based study and first report. Cancer. 116: 2549-59. PMID 20336785 DOI: 10.1002/cncr.25016  0.56
2010 McCabe MT, Powell DR, Zhou W, Vertino PM. Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells. Cancer Genetics and Cytogenetics. 197: 130-41. PMID 20193846 DOI: 10.1016/j.cancergencyto.2009.11.017  0.6
2009 McCabe MT, Brandes JC, Vertino PM. Cancer DNA methylation: molecular mechanisms and clinical implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3927-37. PMID 19509173 DOI: 10.1158/1078-0432.CCR-08-2784  0.36
2009 Lucas ME, Crider KS, Powell DR, Kapoor-Vazirani P, Vertino PM. Methylation-sensitive regulation of TMS1/ASC by the Ets factor, GA-binding protein-alpha. The Journal of Biological Chemistry. 284: 14698-709. PMID 19324871 DOI: 10.1074/jbc.M901104200  0.56
2009 Parsons MJ, Patel P, Brat DJ, Colbert L, Vertino PM. Silencing of TMS1/ASC promotes resistance to anoikis in breast epithelial cells. Cancer Research. 69: 1706-11. PMID 19223547 DOI: 10.1158/0008-5472.CAN-08-2351  0.84
2009 McCabe MT, Lee EK, Vertino PM. A multifactorial signature of DNA sequence and polycomb binding predicts aberrant CpG island methylation. Cancer Research. 69: 282-91. PMID 19118013 DOI: 10.1158/0008-5472.CAN-08-3274  0.36
2008 Kapoor-Vazirani P, Kagey JD, Powell DR, Vertino PM. Role of hMOF-dependent histone H4 lysine 16 acetylation in the maintenance of TMS1/ASC gene activity. Cancer Research. 68: 6810-21. PMID 18701507 DOI: 10.1158/0008-5472.CAN-08-0141  0.8
2008 Subramanian K, Jia D, Kapoor-Vazirani P, Powell DR, Collins RE, Sharma D, Peng J, Cheng X, Vertino PM. Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. Molecular Cell. 30: 336-47. PMID 18471979 DOI: 10.1016/j.molcel.2008.03.022  0.8
2008 Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Research. 68: 740-8. PMID 18245474 DOI: 10.1158/0008-5472.CAN-07-2989  0.56
2008 Evans CO, Moreno CS, Zhan X, McCabe MT, Vertino PM, Desiderio DM, Oyesiku NM. Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses. Pituitary. 11: 231-45. PMID 18183490 DOI: 10.1007/s11102-007-0082-2  0.56
2006 Parsons MJ, Vertino PM. Dual role of TMS1/ASC in death receptor signaling. Oncogene. 25: 6948-58. PMID 16715133 DOI: 10.1038/sj.onc.1209684  0.84
2006 Feltus FA, Lee EK, Costello JF, Plass C, Vertino PM. DNA motifs associated with aberrant CpG island methylation. Genomics. 87: 572-9. PMID 16487676 DOI: 10.1016/j.ygeno.2005.12.016  0.56
2004 Stone AR, Bobo W, Brat DJ, Devi NS, Van Meir EG, Vertino PM. Aberrant methylation and down-regulation of TMS1/ASC in human glioblastoma. The American Journal of Pathology. 165: 1151-61. PMID 15466382 DOI: 10.1016/S0002-9440(10)63376-7  0.4
2003 Levine JJ, Stimson-Crider KM, Vertino PM. Effects of methylation on expression of TMS1/ASC in human breast cancer cells. Oncogene. 22: 3475-88. PMID 12776200 DOI: 10.1038/sj.onc.1206430  1
2002 Costello JF, Vertino PM. Methylation matters: A new spin on maspin Nature Genetics. 31: 123-124. PMID 12040372 DOI: 10.1038/ng0602-123  0.56
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