Gerhard Meissner - Publications

University of North Carolina, Chapel Hill, Chapel Hill, NC 
Molecular Biology, Animal Physiology Biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Xie L, Pi X, Townley-Tilson WH, Li N, Wehrens XH, Entman ML, Taffet GE, Mishra A, Peng J, Schisler JC, Meissner G, Patterson C. PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban. The Journal of Clinical Investigation. 125: 2759-71. PMID 26075818 DOI: 10.1172/JCI80369  0.44
2015 Mei Y, Xu L, Mowrey DD, Mendez Giraldez R, Wang Y, Pasek DA, Dokholyan NV, Meissner G. Channel Gating Dependence on Pore Lining Helix Glycine Residues in Skeletal Muscle Ryanodine Receptor. The Journal of Biological Chemistry. 290: 17535-45. PMID 25998124 DOI: 10.1074/jbc.M115.659672  0.44
2015 Lavorato M, Huang TQ, Iyer VR, Perni S, Meissner G, Franzini-Armstrong C. Dyad content is reduced in cardiac myocytes of mice with impaired calmodulin regulation of RyR2. Journal of Muscle Research and Cell Motility. 36: 205-14. PMID 25694159 DOI: 10.1007/s10974-015-9405-5  0.44
2014 Gillespie D, Xu L, Meissner G. Selecting ions by size in a calcium channel: the ryanodine receptor case study. Biophysical Journal. 107: 2263-73. PMID 25418295 DOI: 10.1016/j.bpj.2014.09.031  0.44
2014 Chakraborty A, Pasek DA, Huang TQ, Gomez AC, Yamaguchi N, Anderson ME, Meissner G. Inhibition of CaMKII does not attenuate cardiac hypertrophy in mice with dysfunctional ryanodine receptor. Plos One. 9: e104338. PMID 25093823 DOI: 10.1371/journal.pone.0104338  0.44
2014 Shirvanyants D, Ramachandran S, Mei Y, Xu L, Meissner G, Dokholyan NV. Pore dynamics and conductance of RyR1 transmembrane domain. Biophysical Journal. 106: 2375-84. PMID 24896116 DOI: 10.1016/J.Bpj.2014.04.023  0.44
2014 Yang Y, Guo T, Oda T, Chakraborty A, Chen L, Uchinoumi H, Knowlton AA, Fruen BR, Cornea RL, Meissner G, Bers DM. Cardiac myocyte Z-line calmodulin is mainly RyR2-bound, and reduction is arrhythmogenic and occurs in heart failure. Circulation Research. 114: 295-306. PMID 24186966 DOI: 10.1161/Circresaha.114.302857  0.44
2013 Arnáiz-Cot JJ, Damon BJ, Zhang XH, Cleemann L, Yamaguchi N, Meissner G, Morad M. Cardiac calcium signalling pathologies associated with defective calmodulin regulation of type 2 ryanodine receptor. The Journal of Physiology. 591: 4287-99. PMID 23836685 DOI: 10.1113/Jphysiol.2013.256123  0.44
2013 Manno C, Figueroa L, Royer L, Pouvreau S, Lee CS, Volpe P, Nori A, Zhou J, Meissner G, Hamilton SL, Ríos E. Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia. The Journal of Physiology. 591: 4439-57. PMID 23798496 DOI: 10.1113/jphysiol.2013.259572  0.44
2013 Mei Y, Xu L, Kramer HF, Tomberlin GH, Townsend C, Meissner G. Stabilization of the skeletal muscle ryanodine receptor ion channel-FKBP12 complex by the 1,4-benzothiazepine derivative S107. Plos One. 8: e54208. PMID 23349825 DOI: 10.1371/Journal.Pone.0054208  0.44
2013 Ramachandran S, Chakraborty A, Xu L, Mei Y, Samsó M, Dokholyan NV, Meissner G. Structural determinants of skeletal muscle ryanodine receptor gating. The Journal of Biological Chemistry. 288: 6154-65. PMID 23319589 DOI: 10.1074/Jbc.M112.433789  0.44
2011 Sun QA, Hess DT, Nogueira L, Yong S, Bowles DE, Eu J, Laurita KR, Meissner G, Stamler JS. Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4. Proceedings of the National Academy of Sciences of the United States of America. 108: 16098-103. PMID 21896730 DOI: 10.1073/Pnas.1109546108  0.44
2011 Yamaguchi N, Prosser BL, Ghassemi F, Xu L, Pasek DA, Eu JP, Hernández-Ochoa EO, Cannon BR, Wilder PT, Lovering RM, Weber D, Melzer W, Schneider MF, Meissner G. Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1. American Journal of Physiology. Cell Physiology. 300: C998-C1012. PMID 21289290 DOI: 10.1152/Ajpcell.00370.2010  0.44
2011 Loy RE, Orynbayev M, Xu L, Andronache Z, Apostol S, Zvaritch E, MacLennan DH, Meissner G, Melzer W, Dirksen RT. Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum. The Journal of General Physiology. 137: 43-57. PMID 21149547 DOI: 10.1085/Jgp.201010523  0.44
2010 Zhou H, Lillis S, Loy RE, Ghassemi F, Rose MR, Norwood F, Mills K, Al-Sarraj S, Lane RJ, Feng L, Matthews E, Sewry CA, Abbs S, Buk S, Hanna M, ... ... Meissner G, et al. Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene. Neuromuscular Disorders : Nmd. 20: 166-73. PMID 20080402 DOI: 10.1016/J.Nmd.2009.12.005  0.44
2009 Ramachandran S, Serohijos AW, Xu L, Meissner G, Dokholyan NV. A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1). Plos Computational Biology. 5: e1000367. PMID 19390614 DOI: 10.1371/Journal.Pcbi.1000367  0.44
2009 Ghassemi F, Vukcevic M, Xu L, Zhou H, Meissner G, Muntoni F, Jungbluth H, Zorzato F, Treves S. A recessive ryanodine receptor 1 mutation in a CCD patient increases channel activity. Cell Calcium. 45: 192-7. PMID 19027160 DOI: 10.1016/J.Ceca.2008.10.001  0.44
2009 Meissner G, Pasek DA, Yamaguchi N, Ramachandran S, Dokholyan NV, Tripathy A. Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels. Proteins. 74: 207-11. PMID 18618700 DOI: 10.1002/Prot.22148  0.44
2008 Sun J, Yamaguchi N, Xu L, Eu JP, Stamler JS, Meissner G. Regulation of the cardiac muscle ryanodine receptor by O(2) tension and S-nitrosoglutathione. Biochemistry. 47: 13985-90. PMID 19053230 DOI: 10.1021/Bi8012627  0.44
2008 Stiber JA, Zhang ZS, Burch J, Eu JP, Zhang S, Truskey GA, Seth M, Yamaguchi N, Meissner G, Shah R, Worley PF, Williams RS, Rosenberg PB. Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. Molecular and Cellular Biology. 28: 2637-47. PMID 18268005 DOI: 10.1128/Mcb.01601-07  0.44
2008 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proceedings of the National Academy of Sciences of the United States of America. 105: 2111-6. PMID 18256189 DOI: 10.1073/Pnas.0710228105  0.44
2007 Yamaguchi N, Takahashi N, Xu L, Smithies O, Meissner G. Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel. The Journal of Clinical Investigation. 117: 1344-53. PMID 17431507 DOI: 10.1172/Jci29515  0.44
2007 Lyfenko AD, Ducreux S, Wang Y, Xu L, Zorzato F, Ferreiro A, Meissner G, Treves S, Dirksen RT. Two central core disease (CCD) deletions in the C-terminal region of RYR1 alter muscle excitation-contraction (EC) coupling by distinct mechanisms. Human Mutation. 28: 61-8. PMID 16958053 DOI: 10.1002/Humu.20409  0.44
2006 Petrotchenko EV, Pasek D, Elms P, Dokholyan NV, Meissner G, Borchers CH. Combining fluorescence detection and mass spectrometric analysis for comprehensive and quantitative analysis of redox-sensitive cysteines in native membrane proteins. Analytical Chemistry. 78: 7959-66. PMID 17134128 DOI: 10.1021/Ac060238R  0.44
2006 Zhou H, Yamaguchi N, Xu L, Wang Y, Sewry C, Jungbluth H, Zorzato F, Bertini E, Muntoni F, Meissner G, Treves S. Characterization of recessive RYR1 mutations in core myopathies. Human Molecular Genetics. 15: 2791-803. PMID 16940308 DOI: 10.1093/Hmg/Ddl221  0.44
2003 Matalon S, Hardiman KM, Jain L, Eaton DC, Kotlikoff M, Eu JP, Sun J, Meissner G, Stamler JS. Regulation of ion channel structure and function by reactive oxygen-nitrogen species. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1184-9. PMID 14604848 DOI: 10.1152/Ajplung.00281.2003  0.44
2003 Stange M, Xu L, Balshaw D, Yamaguchi N, Meissner G. Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants. The Journal of Biological Chemistry. 278: 51693-702. PMID 14532276 DOI: 10.1074/jbc.M310406200  0.44
2003 Bidasee KR, Xu L, Meissner G, Besch HR. Diketopyridylryanodine has three concentration-dependent effects on the cardiac calcium-release channel/ryanodine receptor. The Journal of Biological Chemistry. 278: 14237-48. PMID 12566457 DOI: 10.1074/jbc.M208372200  0.44
2003 Zorzato F, Yamaguchi N, Xu L, Meissner G, Müller CR, Pouliquin P, Muntoni F, Sewry C, Girard T, Treves S. Clinical and functional effects of a deletion in a COOH-terminal lumenal loop of the skeletal muscle ryanodine receptor. Human Molecular Genetics. 12: 379-88. PMID 12566385 DOI: 10.1093/Hmg/Ddg032  0.44
2003 Tijskens P, Meissner G, Franzini-Armstrong C. Location of ryanodine and dihydropyridine receptors in frog myocardium. Biophysical Journal. 84: 1079-92. PMID 12547789 DOI: 10.1016/S0006-3495(03)74924-8  0.44
2003 Sun J, Xu L, Eu JP, Stamler JS, Meissner G. Nitric oxide, NOC-12, and S-nitrosoglutathione modulate the skeletal muscle calcium release channel/ryanodine receptor by different mechanisms. An allosteric function for O2 in S-nitrosylation of the channel. The Journal of Biological Chemistry. 278: 8184-9. PMID 12509428 DOI: 10.1074/Jbc.M211940200  0.44
2003 Chen DP, Xu L, Eisenberg B, Meissner G. Calcium ion permeation through the calcium release channel (ryanodine receptor) of cardiac muscle Journal of Physical Chemistry B. 107: 9139-9145.  0.44
2002 O'Connell KM, Yamaguchi N, Meissner G, Dirksen RT. Calmodulin binding to the 3614-3643 region of RyR1 is not essential for excitation-contraction coupling in skeletal myotubes. The Journal of General Physiology. 120: 337-47. PMID 12198090 DOI: 10.1085/Jgp.20028617  0.44
2002 Wang SQ, Song LS, Xu L, Meissner G, Lakatta EG, Ríos E, Stern MD, Cheng H. Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks. Biophysical Journal. 83: 242-51. PMID 12080116 DOI: 10.1016/S0006-3495(02)75165-5  0.44
2001 Sun J, Xin C, Eu JP, Stamler JS, Meissner G. Cysteine-3635 is responsible for skeletal muscle ryanodine receptor modulation by NO. Proceedings of the National Academy of Sciences of the United States of America. 98: 11158-62. PMID 11562475 DOI: 10.1073/Pnas.201289098  0.44
2001 Stange M, Tripathy A, Meissner G. Two domains in dihydropyridine receptor activate the skeletal muscle Ca(2+) release channel. Biophysical Journal. 81: 1419-29. PMID 11509356 DOI: 10.1016/S0006-3495(01)75797-9  0.44
2001 Sun J, Xu L, Eu JP, Stamler JS, Meissner G. Classes of thiols that influence the activity of the skeletal muscle calcium release channel. The Journal of Biological Chemistry. 276: 15625-30. PMID 11278999 DOI: 10.1074/Jbc.M100083200  0.44
2000 Protasi F, Takekura H, Wang Y, Chen SR, Meissner G, Allen PD, Franzini-Armstrong C. RYR1 and RYR3 have different roles in the assembly of calcium release units of skeletal muscle. Biophysical Journal. 79: 2494-508. PMID 11053125 DOI: 10.1016/S0006-3495(00)76491-5  0.44
2000 Morrissette J, Xu L, Nelson A, Meissner G, Block BA. Characterization of RyR1-slow, a ryanodine receptor specific to slow-twitch skeletal muscle. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 279: R1889-98. PMID 11049875 DOI: 10.1152/AJPREGU.2000.279.5.R1889  0.44
2000 Eu JP, Sun J, Xu L, Stamler JS, Meissner G. The skeletal muscle calcium release channel: coupled O2 sensor and NO signaling functions. Cell. 102: 499-509. PMID 10966111 DOI: 10.1016/S0092-8674(00)00054-4  0.44
2000 Gao L, Balshaw D, Xu L, Tripathy A, Xin C, Meissner G. Evidence for a role of the lumenal M3-M4 loop in skeletal muscle Ca(2+) release channel (ryanodine receptor) activity and conductance. Biophysical Journal. 79: 828-40. PMID 10920015 DOI: 10.1016/S0006-3495(00)76339-9  0.44
1999 Eu JP, Xu L, Stamler JS, Meissner G. Regulation of ryanodine receptors by reactive nitrogen species. Biochemical Pharmacology. 57: 1079-84. PMID 11230795 DOI: 10.1016/S0006-2952(98)00360-8  0.44
1999 Xu L, Tripathy A, Pasek DA, Meissner G. Ruthenium red modifies the cardiac and skeletal muscle Ca(2+) release channels (ryanodine receptors) by multiple mechanisms. The Journal of Biological Chemistry. 274: 32680-91. PMID 10551824 DOI: 10.1074/jbc.274.46.32680  0.44
1999 Chen DP, Xu L, Tripathy A, Meissner G, Eisenberg B. Selectivity and permeation in calcium release channel of cardiac muscle: alkali metal ions. Biophysical Journal. 76: 1346-66. PMID 10049318 DOI: 10.1016/S0006-3495(99)77297-8  0.44
1998 Xu L, Tripathy A, Pasek DA, Meissner G. Potential for pharmacology of ryanodine receptor/calcium release channels. Annals of the New York Academy of Sciences. 853: 130-48. PMID 10603942 DOI: 10.1111/J.1749-6632.1998.TB08262.X  0.44
1998 Xu L, Eu JP, Meissner G, Stamler JS. Activation of the cardiac calcium release channel (Ryanodoine receptor) by poly-S-nitrosylation Science. 279: 234-237. PMID 9422697 DOI: 10.1126/Science.279.5348.234  0.44
1997 Chen D, Xu L, Tripathy A, Meissner G, Eisenberg B. Permeation through the calcium release channel of cardiac muscle. Biophysical Journal. 73: 1337-54. PMID 9284302 DOI: 10.1016/S0006-3495(97)78167-0  0.44
1997 Gao L, Tripathy A, Lu X, Meissner G. Evidence for a role of C-terminal amino acid residues in skeletal muscle Ca2+ release channel (ryanodine receptor) function. Febs Letters. 412: 223-6. PMID 9257724 DOI: 10.1016/S0014-5793(97)00781-3  0.44
1997 Meissner G, Rios E, Tripathy A, Pasek DA. Regulation of skeletal muscle Ca2+ release channel (ryanodine receptor) by Ca2+ and monovalent cations and anions. The Journal of Biological Chemistry. 272: 1628-38. PMID 8999838 DOI: 10.1074/jbc.272.3.1628  0.44
1996 Tripathy A, Meissner G. Sarcoplasmic reticulum lumenal Ca2+ has access to cytosolic activation and inactivation sites of skeletal muscle Ca2+ release channel. Biophysical Journal. 70: 2600-15. PMID 8744299 DOI: 10.1016/S0006-3495(96)79831-4  0.44
1996 Delbono O, Meissner G. Sarcoplasmic Reticulum Ca2+ Release in Rat Slow- and Fast-Twitch Muscles Journal of Membrane Biology. 151: 123-130. PMID 8661500 DOI: 10.1007/S002329900063  0.44
1995 Tripathy A, Xu L, Mann G, Meissner G. Calmodulin activation and inhibition of skeletal muscle Ca2+ release channel (ryanodine receptor). Biophysical Journal. 69: 106-19. PMID 7669888 DOI: 10.1016/S0006-3495(95)79880-0  0.44
1994 Block BA, O'Brien J, Meissner G. Characterization of the sarcoplasmic reticulum proteins in the thermogenic muscles of fish. The Journal of Cell Biology. 127: 1275-87. PMID 7962089 DOI: 10.1083/jcb.127.5.1275  0.44
1993 O'Brien J, Meissner G, Block BA. The fastest contracting muscles of nonmammalian vertebrates express only one isoform of the ryanodine receptor. Biophysical Journal. 65: 2418-27. PMID 8312480 DOI: 10.1016/S0006-3495(93)81303-1  0.44
1990 Jones RV, Rousseau E, Meissner G. Comparison of CHAPS-induced current fluctuations with sarcoplasmic reticulum Ca2+ release channel activity. Membrane Biochemistry. 9: 171-8. PMID 1966912 DOI: 10.3109/09687689009025838  0.44
1989 Liu QY, Lai FA, Rousseau E, Jones RV, Meissner G. Multiple conductance states of the purified calcium release channel complex from skeletal sarcoplasmic reticulum. Biophysical Journal. 55: 415-24. PMID 2539209 DOI: 10.1016/S0006-3495(89)82835-8  0.44
1989 Xu L, Jones RV, Meissner G. Activation of the skeletal muscle Ca2+ release channel by the triazine dyes cibacron blue F3A-G and reactive red 120. Archives of Biochemistry and Biophysics. 274: 609-16. PMID 2478077 DOI: 10.1016/0003-9861(89)90476-1  0.44
1988 Meissner G, Rousseau E, Lai FA, Liu QY, Anderson KA. Biochemical characterization of the Ca2+ release channel of skeletal and cardiac sarcoplasmic reticulum Molecular and Cellular Biochemistry. 82: 59-65. PMID 2847014 DOI: 10.1007/BF00242517  0.44
1987 Lai FA, Erickson H, Block BA, Meissner G. Evidence for a junctional feet-ryanodine receptor complex from sarcoplasmic reticulum. Biochemical and Biophysical Research Communications. 143: 704-9. PMID 2436616 DOI: 10.1016/0006-291X(87)91411-2  0.44
1983 Lentz BR, Clubb KW, Barrow DA, Meissner G. Ordered and disordered phospholipid domains coexist in membranes containing the calcium pump protein of sarcoplasmic reticulum Proceedings of the National Academy of Sciences of the United States of America. 80: 2917-2921. PMID 6222375  0.44
1981 Moore BM, Lentz BR, Hoechli M, Meissner G. Effect of lipid membrane structure on the adenosine 5′-triphosphate hydrolyzing activity of the calcium-stimulated adenosinetriphosphatase of sarcoplasmic reticulum Biochemistry. 20: 6810-6817. PMID 6459119  0.44
1979 Levine SN, Steiner AL, Earp HS, Meissner G. Particulate guanylate cyclase of skeletal muscle. Effects of Ca2+ and other divalent cations on enzyme activity Bba - Enzymology. 566: 171-182. PMID 31938 DOI: 10.1016/0005-2744(79)90259-6  0.44
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