Jeffery D. Molkentin - Publications

Affiliations: 
University of Cincinnati, Cincinnati, OH 
Area:
Molecular Biology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, ... ... Molkentin JD, et al. Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death and Differentiation. PMID 29362479 DOI: 10.1038/s41418-017-0012-4  0.8
2017 Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, et al. The mitochondrial Na(+)/Ca(2+) exchanger is essential for Ca(2+) homeostasis and viability. Nature. PMID 28445457 DOI: 10.1038/nature22082  0.8
2016 Vanhoutte D, Schips TG, Kwong JQ, Davis J, Tjondrokoesoemo A, Brody MJ, Sargent MA, Kanisicak O, Yi H, Gao QQ, Rabinowitz JE, Volk T, McNally EM, Molkentin JD. Thrombospondin expression in myofibers stabilizes muscle membranes. Elife. 5. PMID 27669143 DOI: 10.7554/eLife.17589  0.84
2016 Wallner M, Duran JM, Mohsin S, Troupes CD, Vanhoutte D, Borghetti G, Vagnozzi RJ, Gross P, Yu D, Trappanese DM, Kubo H, Toib A, Sharp TE, Harper SC, Volkert MA, ... ... Molkentin JD, et al. Acute Catecholamine Exposure Causes Reversible Myocyte Injury Without Cardiac Regeneration. Circulation Research. PMID 27461939 DOI: 10.1161/CIRCRESAHA.116.308687  0.84
2016 Kanisicak O, Khalil H, Ivey MJ, Karch J, Maliken BD, Correll RN, Brody MJ, J Lin SC, Aronow BJ, Tallquist MD, Molkentin JD. Genetic lineage tracing defines myofibroblast origin and function in the injured heart. Nature Communications. 7: 12260. PMID 27447449 DOI: 10.1038/ncomms12260  0.84
2016 Liu R, van Berlo JH, York AJ, Maillet M, Vagnozzi RJ, Molkentin JD. DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling. Circulation Research. PMID 27225478 DOI: 10.1161/CIRCRESAHA.115.308238  0.84
2016 Lamar KM, Bogdanovich S, Gardner BB, Gao QQ, Miller T, Earley JU, Hadhazy M, Vo AH, Wren L, Molkentin JD, McNally EM. Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ. Plos Genetics. 12: e1006019. PMID 27148972 DOI: 10.1371/journal.pgen.1006019  0.84
2016 Tjondrokoesoemo A, Schips TG, Sargent MA, Vanhoutte D, Kanisicak O, Prasad V, Lin SJ, Maillet M, Molkentin JD. Cathepsin S contributes to the pathogenesis of muscular dystrophy in mice. The Journal of Biological Chemistry. PMID 26966179 DOI: 10.1074/jbc.M116.719054  0.84
2015 Davis J, Salomonis N, Ghearing N, Lin SC, Kwong JQ, Mohan A, Swanson MS, Molkentin JD. MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response. Nature Communications. 6: 10084. PMID 26670661 DOI: 10.1038/ncomms10084  0.84
2015 Li L, Chen Y, Li J, Yin H, Guo X, Doan J, Molkentin JD, Liu Q. TAK1 Regulates Myocardial Response to Pathological Stress via NFAT, NFκB, and Bnip3 Pathways. Scientific Reports. 5: 16626. PMID 26564789 DOI: 10.1038/srep16626  0.84
2015 Brody MJ, Schips TG, Vanhoutte D, Kanisicak O, Karch J, Maliken BD, Blair NS, Sargent MA, Prasad V, Molkentin JD. Dissection of thrombospondin-4 domains involved in intracellular adaptive ER Stress responsive signaling. Molecular and Cellular Biology. PMID 26459760 DOI: 10.1128/MCB.00607-15  0.84
2015 Pfluger PT, Kabra DG, Aichler M, Schriever SC, Pfuhlmann K, García VC, Lehti M, Weber J, Kutschke M, Rozman J, Elrod JW, Hevener AL, Feuchtinger A, Hrabě de Angelis M, Walch A, ... ... Molkentin JD, et al. Calcineurin Links Mitochondrial Elongation with Energy Metabolism. Cell Metabolism. PMID 26411342 DOI: 10.1016/j.cmet.2015.08.022  0.8
2015 Correll RN, Goonasekera SA, van Berlo JH, Burr AR, Accornero F, Zhang H, Makarewich CA, York AJ, Sargent MA, Chen X, Houser SR, Molkentin JD. STIM1 elevation in the heart results in aberrant Ca(2+) handling and cardiomyopathy. Journal of Molecular and Cellular Cardiology. PMID 26241845 DOI: 10.1016/j.yjmcc.2015.07.032  0.84
2015 Kwong JQ, Lu X, Correll RN, Schwanekamp JA, Vagnozzi RJ, Sargent MA, York AJ, Zhang J, Bers DM, Molkentin JD. The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart. Cell Reports. PMID 26119742 DOI: 10.1016/j.celrep.2015.06.002  0.84
2015 Mukherjee R, Mareninova OA, Odinokova IV, Huang W, Murphy J, Chvanov M, Javed MA, Wen L, Booth DM, Cane MC, Awais M, Gavillet B, Pruss RM, Schaller S, Molkentin JD, et al. Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP. Gut. PMID 26071131 DOI: 10.1136/gutjnl-2014-308553  0.84
2015 Karch J, Kanisicak O, Brody MJ, Sargent MA, Michael DM, Molkentin JD. Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death. Plos One. 10: e0130520. PMID 26061004 DOI: 10.1371/journal.pone.0130520  0.84
2015 Accornero F, van Berlo JH, Correll RN, Elrod JW, Sargent MA, York A, Rabinowitz JE, Leask A, Molkentin JD. Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling. Molecular and Cellular Biology. 35: 2154-64. PMID 25870108 DOI: 10.1128/MCB.00199-15  0.84
2015 Mázala DA, Pratt SJ, Chen D, Molkentin JD, Lovering RM, Chin ER. SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models. American Journal of Physiology. Cell Physiology. 308: C699-709. PMID 25652448 DOI: 10.1152/ajpcell.00341.2014  0.84
2015 Kwong JQ, Molkentin JD. Physiological and pathological roles of the mitochondrial permeability transition pore in the heart. Cell Metabolism. 21: 206-14. PMID 25651175 DOI: 10.1016/j.cmet.2014.12.001  0.84
2014 Ceco E, Bogdanovich S, Gardner B, Miller T, DeJesus A, Earley JU, Hadhazy M, Smith LR, Barton ER, Molkentin JD, McNally EM. Targeting latent TGFβ release in muscular dystrophy. Science Translational Medicine. 6: 259ra144. PMID 25338755 DOI: 10.1126/scitranslmed.3010018  0.84
2014 Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI. RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis. Science Signaling. 7: ra100. PMID 25336613 DOI: 10.1126/scisignal.2005262  0.84
2014 Li L, Chen Y, Doan J, Murray J, Molkentin JD, Liu Q. Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling. Circulation. 130: 2162-72. PMID 25278099 DOI: 10.1161/CIRCULATIONAHA.114.011195  0.84
2014 Gupta MK, Gulick J, Liu R, Wang X, Molkentin JD, Robbins J. Sumo E2 enzyme UBC9 is required for efficient protein quality control in cardiomyocytes. Circulation Research. 115: 721-9. PMID 25097219 DOI: 10.1161/CIRCRESAHA.115.304760  0.84
2014 Makarewich CA, Zhang H, Davis J, Correll RN, Trappanese DM, Hoffman NE, Troupes CD, Berretta RM, Kubo H, Madesh M, Chen X, Gao E, Molkentin JD, Houser SR. Transient receptor potential channels contribute to pathological structural and functional remodeling after myocardial infarction. Circulation Research. 115: 567-80. PMID 25047165 DOI: 10.1161/CIRCRESAHA.115.303831  0.84
2014 Tane S, Kubota M, Okayama H, Ikenishi A, Yoshitome S, Iwamoto N, Satoh Y, Kusakabe A, Ogawa S, Kanai A, Molkentin JD, Nakamura K, Ohbayashi T, Takeuchi T. Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes. The Journal of Biological Chemistry. 289: 18033-44. PMID 24821722 DOI: 10.1074/jbc.M113.541953  0.84
2014 van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SC, Middleton RC, Marbán E, Molkentin JD. c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature. 509: 337-41. PMID 24805242 DOI: 10.1038/nature13309  0.84
2014 Gutiérrez-Aguilar M, Douglas DL, Gibson AK, Domeier TL, Molkentin JD, Baines CP. Genetic manipulation of the cardiac mitochondrial phosphate carrier does not affect permeability transition. Journal of Molecular and Cellular Cardiology. 72: 316-25. PMID 24768964 DOI: 10.1016/j.yjmcc.2014.04.008  0.84
2014 Goonasekera SA, Davis J, Kwong JQ, Accornero F, Wei-LaPierre L, Sargent MA, Dirksen RT, Molkentin JD. Enhanced Ca²⁺ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy. Human Molecular Genetics. 23: 3706-15. PMID 24556214 DOI: 10.1093/hmg/ddu079  0.84
2014 Molkentin JD, Houser SR. Response to Torella et al. Circulation Research. 114: e27. PMID 24526680 DOI: 10.1161/CIRCRESAHA.114.303361  0.84
2014 Correll RN, Eder P, Burr AR, Despa S, Davis J, Bers DM, Molkentin JD. Overexpression of the Na+/K+ ATPase α2 but not α1 isoform attenuates pathological cardiac hypertrophy and remodeling. Circulation Research. 114: 249-56. PMID 24218169 DOI: 10.1161/CIRCRESAHA.114.302293  0.84
2013 Davis J, Kwong JQ, Kitsis RN, Molkentin JD. Apoptosis repressor with a CARD domain (ARC) restrains Bax-mediated pathogenesis in dystrophic skeletal muscle. Plos One. 8: e82053. PMID 24312627 DOI: 10.1371/journal.pone.0082053  0.84
2013 Braitsch CM, Kanisicak O, van Berlo JH, Molkentin JD, Yutzey KE. Differential expression of embryonic epicardial progenitor markers and localization of cardiac fibrosis in adult ischemic injury and hypertensive heart disease. Journal of Molecular and Cellular Cardiology. 65: 108-19. PMID 24140724 DOI: 10.1016/j.yjmcc.2013.10.005  0.84
2013 Molkentin JD, Houser SR. Are resident c-Kit+ cardiac stem cells really all that are needed to mend a broken heart? Circulation Research. 113: 1037-9. PMID 24115067 DOI: 10.1161/CIRCRESAHA.113.302564  0.84
2013 Karch J, Kwong JQ, Burr AR, Sargent MA, Elrod JW, Peixoto PM, Martinez-Caballero S, Osinska H, Cheng EH, Robbins J, Kinnally KW, Molkentin JD. Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice. Elife. 2: e00772. PMID 23991283 DOI: 10.7554/eLife.00772  0.8
2013 Correll RN, Molkentin JD. CaMKII does it again: even the mitochondria cannot escape its influence. Circulation Research. 112: 1208-11. PMID 23620234 DOI: 10.1161/CIRCRESAHA.113.301263  0.84
2013 Elrod JW, Molkentin JD. Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore. Circulation Journal : Official Journal of the Japanese Circulation Society. 77: 1111-22. PMID 23538482 DOI: DN/JST.JSTAGE/circj/CJ-13-0321  0.8
2013 Nicholson CK, Lambert JP, Molkentin JD, Sadoshima J, Calvert JW. Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 744-51. PMID 23349187 DOI: 10.1161/ATVBAHA.112.300484  0.84
2013 Suk HY, Zhou C, Yang TT, Zhu H, Yu RY, Olabisi O, Yang X, Brancho D, Kim JY, Scherer PE, Frank PG, Lisanti MP, Calvert JW, Lefer DJ, Molkentin JD, et al. Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. The Journal of Biological Chemistry. 288: 3477-88. PMID 23258544 DOI: 10.1074/jbc.M112.419150  0.84
2013 Auger-Messier M, Accornero F, Goonasekera SA, Bueno OF, Lorenz JN, van Berlo JH, Willette RN, Molkentin JD. Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy. Circulation Research. 112: 48-56. PMID 22993413 DOI: 10.1161/CIRCRESAHA.112.272963  0.84
2012 Drawnel FM, Wachten D, Molkentin JD, Maillet M, Aronsen JM, Swift F, Sjaastad I, Liu N, Catalucci D, Mikoshiba K, Hisatsune C, Okkenhaug H, Andrews SR, Bootman MD, Roderick HL. Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy. The Journal of Cell Biology. 199: 783-98. PMID 23166348 DOI: 10.1083/jcb.201111095  0.84
2012 Schulz EM, Correll RN, Sheikh HN, Lofrano-Alves MS, Engel PL, Newman G, Schultz JEJ, Molkentin JD, Wolska BM, Solaro RJ, Wieczorek DF. Tropomyosin dephosphorylation results in compensated cardiac hypertrophy Journal of Biological Chemistry. 287: 44478-44489. PMID 23148217 DOI: 10.1074/jbc.M112.402040  0.84
2012 Davis J, Burr AR, Davis GF, Birnbaumer L, Molkentin JD. A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo. Developmental Cell. 23: 705-15. PMID 23022034 DOI: 10.1016/j.devcel.2012.08.017  0.84
2012 Gao H, Wang F, Wang W, Makarewich CA, Zhang H, Kubo H, Berretta RM, Barr LA, Molkentin JD, Houser SR. Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling. Journal of Molecular and Cellular Cardiology. 53: 657-67. PMID 22921230 DOI: 10.1016/j.yjmcc.2012.08.005  0.84
2012 Lynch JM, Maillet M, Vanhoutte D, Schloemer A, Sargent MA, Blair NS, Lynch KA, Okada T, Aronow BJ, Osinska H, Prywes R, Lorenz JN, Mori K, Lawler J, Robbins J, ... Molkentin JD, et al. A thrombospondin-dependent pathway for a protective ER stress response. Cell. 149: 1257-68. PMID 22682248 DOI: 10.1016/j.cell.2012.03.050  0.84
2012 Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ, Koch W. Animal models of heart failure: a scientific statement from the American Heart Association. Circulation Research. 111: 131-50. PMID 22595296 DOI: 10.1161/RES.0b013e3182582523  0.84
2012 Makarewich CA, Correll RN, Gao H, Zhang H, Yang B, Berretta RM, Rizzo V, Molkentin JD, Houser SR. A caveolae-targeted L-type Ca²+ channel antagonist inhibits hypertrophic signaling without reducing cardiac contractility. Circulation Research. 110: 669-74. PMID 22302787 DOI: 10.1161/CIRCRESAHA.111.264028  0.84
2012 Goonasekera SA, Hammer K, Auger-Messier M, Bodi I, Chen X, Zhang H, Reiken S, Elrod JW, Correll RN, York AJ, Sargent MA, Hofmann F, Moosmang S, Marks AR, Houser SR, ... ... Molkentin JD, et al. Decreased cardiac L-type Ca²⁺ channel activity induces hypertrophy and heart failure in mice. The Journal of Clinical Investigation. 122: 280-90. PMID 22133878 DOI: 10.1172/JCI58227  0.84
2011 Ladage D, Tilemann L, Ishikawa K, Correll RN, Kawase Y, Houser SR, Molkentin JD, Hajjar RJ. Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury. Circulation Research. 109: 1396-400. PMID 21998327 DOI: 10.1161/CIRCRESAHA.111.255687  0.84
2011 Hom JR, Quintanilla RA, Hoffman DL, de Mesy Bentley KL, Molkentin JD, Sheu SS, Porter GA. The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation. Developmental Cell. 21: 469-78. PMID 21920313 DOI: 10.1016/j.devcel.2011.08.008  0.84
2011 Xiang SY, Vanhoutte D, Del Re DP, Purcell NH, Ling H, Banerjee I, Bossuyt J, Lang RA, Zheng Y, Matkovich SJ, Miyamoto S, Molkentin JD, Dorn GW, Brown JH. RhoA protects the mouse heart against ischemia/reperfusion injury. The Journal of Clinical Investigation. 121: 3269-76. PMID 21747165 DOI: 10.1172/JCI44371  0.84
2011 van Berlo JH, Elrod JW, Aronow BJ, Pu WT, Molkentin JD. Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 12331-6. PMID 21746915 DOI: 10.1073/pnas.1104499108  0.8
2011 Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, ... ... Molkentin JD, et al. Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. The Journal of Cell Biology. 193: 1181-96. PMID 21690310 DOI: 10.1083/jcb.201006114  0.84
2011 Accornero F, Van Berlo JH, Benard MJ, Lorenz JN, Carmeliet P, Molkentin JD. Placental growth factor regulates cardiac adaptation and hypertrophy through a paracrine mechanism Circulation Research. 109: 272-280. PMID 21636802 DOI: 10.1161/CIRCRESAHA.111.240820  0.84
2011 Stefater JA, Lewkowich I, Rao S, Mariggi G, Carpenter AC, Burr AR, Fan J, Ajima R, Molkentin JD, Williams BO, Wills-Karp M, Pollard JW, Yamaguchi T, Ferrara N, Gerhardt H, et al. Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells. Nature. 474: 511-5. PMID 21623369 DOI: 10.1038/nature10085  0.84
2011 Sadayappan S, Gulick J, Osinska H, Barefield D, Cuello F, Avkiran M, Lasko VM, Lorenz JN, Maillet M, Martin JL, Brown JH, Bers DM, Molkentin JD, James J, Robbins J. A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function. Circulation Research. 109: 141-50. PMID 21597010 DOI: 10.1161/CIRCRESAHA.111.242560  0.84
2011 Meissner M, Weissgerber P, Londoño JE, Prenen J, Link S, Ruppenthal S, Molkentin JD, Lipp P, Nilius B, Freichel M, Flockerzi V. Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene. The Journal of Biological Chemistry. 286: 15875-82. PMID 21357697 DOI: 10.1074/jbc.M111.227819  0.84
2011 Goonasekera SA, Lam CK, Millay DP, Sargent MA, Hajjar RJ, Kranias EG, Molkentin JD. Mitigation of muscular dystrophy in mice by SERCA overexpression in skeletal muscle. The Journal of Clinical Investigation. 121: 1044-52. PMID 21285509 DOI: 10.1172/JCI43844  0.84
2011 Sengupta A, Molkentin JD, Paik JH, DePinho RA, Yutzey KE. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. The Journal of Biological Chemistry. 286: 7468-78. PMID 21159781 DOI: 10.1074/jbc.M110.179242  0.84
2011 Kehat I, Davis J, Tiburcy M, Accornero F, Saba-El-Leil MK, Maillet M, York AJ, Lorenz JN, Zimmermann WH, Meloche S, Molkentin JD. Extracellular signal-regulated kinases 1 and 2 regulate the balance between eccentric and concentric cardiac growth. Circulation Research. 108: 176-83. PMID 21127295 DOI: 10.1161/CIRCRESAHA.110.231514  0.84
2010 Elrod JW, Wong R, Mishra S, Vagnozzi RJ, Sakthievel B, Goonasekera SA, Karch J, Gabel S, Farber J, Force T, Brown JH, Murphy E, Molkentin JD. Cyclophilin D controls mitochondrial pore-dependent Ca(2+) exchange, metabolic flexibility, and propensity for heart failure in mice. The Journal of Clinical Investigation. 120: 3680-7. PMID 20890047 DOI: 10.1172/JCI43171  0.84
2010 van Berlo JH, Elrod JW, van den Hoogenhof MM, York AJ, Aronow BJ, Duncan SA, Molkentin JD. The transcription factor GATA-6 regulates pathological cardiac hypertrophy. Circulation Research. 107: 1032-40. PMID 20705924 DOI: 10.1161/CIRCRESAHA.110.220764  0.84
2009 Lorts A, Schwanekamp JA, Elrod JW, Sargent MA, Molkentin JD. Genetic manipulation of periostin expression in the heart does not affect myocyte content, cell cycle activity, or cardiac repair. Circulation Research. 104: e1-7. PMID 19038863 DOI: 10.1161/CIRCRESAHA.108.188649  0.8
2007 Purcell NH, Wilkins BJ, York A, Saba-El-Leil MK, Meloche S, Robbins J, Molkentin JD. Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 14074-9. PMID 17709754 DOI: 10.1073/pnas.0610906104  0.84
2007 Davies KJ, Ermak G, Rothermel BA, Pritchard M, Heitman J, Ahnn J, Henrique-Silva F, Crawford D, Canaider S, Strippoli P, Carinci P, Min KT, Fox DS, Cunningham KW, Bassel-Duby R, ... ... Molkentin JD, et al. Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3023-8. PMID 17595344 DOI: 10.1096/fj.06-7246com  0.84
2007 Parsons SA, Millay DP, Sargent MA, Naya FJ, McNally EM, Sweeney HL, Molkentin JD. Genetic disruption of calcineurin improves skeletal muscle pathology and cardiac disease in a mouse model of limb-girdle muscular dystrophy. The Journal of Biological Chemistry. 282: 10068-78. PMID 17289669 DOI: 10.1074/jbc.M609368200  0.84
2006 Xin M, Davis CA, Molkentin JD, Lien CL, Duncan SA, Richardson JA, Olson EN. A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proceedings of the National Academy of Sciences of the United States of America. 103: 11189-94. PMID 16847256 DOI: 10.1073/pnas.0604604103  0.32
2006 Parsons SA, Millay DP, Sargent MA, McNally EM, Molkentin JD. Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy. The American Journal of Pathology. 168: 1975-85. PMID 16723712 DOI: 10.2353/ajpath.2006.051316  0.84
2006 Liu Q, Wilkins BJ, Lee YJ, Ichijo H, Molkentin JD. Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth. Molecular and Cellular Biology. 26: 3785-97. PMID 16648474 DOI: 10.1128/MCB.26.10.3785-3797.2006  0.84
2005 Sanna B, Bueno OF, Dai YS, Wilkins BJ, Molkentin JD. Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth. Molecular and Cellular Biology. 25: 865-78. PMID 15657416 DOI: 10.1128/MCB.25.3.865-878.2005  0.84
2004 Wilkins BJ, Molkentin JD. Calcium-calcineurin signaling in the regulation of cardiac hypertrophy. Biochemical and Biophysical Research Communications. 322: 1178-91. PMID 15336966 DOI: 10.1016/j.bbrc.2004.07.121  0.84
2004 Lips DJ, Bueno OF, Wilkins BJ, Purcell NH, Kaiser RA, Lorenz JN, Voisin L, Saba-El-Leil MK, Meloche S, Pouysségur J, Pagès G, De Windt LJ, Doevendans PA, Molkentin JD. MEK1-ERK2 signaling pathway protects myocardium from ischemic injury in vivo. Circulation. 109: 1938-41. PMID 15096454 DOI: 10.1161/01.CIR.0000127126.73759.23  0.84
2004 Parsons SA, Millay DP, Wilkins BJ, Bueno OF, Tsika GL, Neilson JR, Liberatore CM, Yutzey KE, Crabtree GR, Tsika RW, Molkentin JD. Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy. The Journal of Biological Chemistry. 279: 26192-200. PMID 15082723 DOI: 10.1074/jbc.M313800200  0.84
2004 Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM, Jones F, Kimball TR, Molkentin JD. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circulation Research. 94: 110-8. PMID 14656927 DOI: 10.1161/01.RES.0000109415.17511.18  0.84
2004 Bueno OF, Lips DJ, Kaiser RA, Wilkins BJ, Dai YS, Glascock BJ, Klevitsky R, Hewett TE, Kimball TR, Aronow BJ, Doevendans PA, Molkentin JD. Calcineurin Abeta gene targeting predisposes the myocardium to acute ischemia-induced apoptosis and dysfunction. Circulation Research. 94: 91-9. PMID 14615291 DOI: 10.1161/01.RES.0000107197.99679.77  0.84
2003 Liang Q, Bueno OF, Wilkins BJ, Kuan CY, Xia Y, Molkentin JD. c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling. The Embo Journal. 22: 5079-89. PMID 14517246 DOI: 10.1093/emboj/cdg474  0.84
2003 Parsons SA, Wilkins BJ, Bueno OF, Molkentin JD. Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice. Molecular and Cellular Biology. 23: 4331-43. PMID 12773574 DOI: 10.1128/MCB.23.12.4331-4343.2003  0.84
2003 Braz JC, Bueno OF, Liang Q, Wilkins BJ, Dai YS, Parsons S, Braunwart J, Glascock BJ, Klevitsky R, Kimball TF, Hewett TE, Molkentin JD. Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. The Journal of Clinical Investigation. 111: 1475-86. PMID 12750397 DOI: 10.1172/JCI17295  0.84
2003 Gajewski K, Wang J, Molkentin JD, Chen EH, Olson EN, Schulz RA. Requirement of the calcineurin subunit gene canB2 for indirect flight muscle formation in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 100: 1040-5. PMID 12538857 DOI: 10.1073/pnas.0337662100  0.84
2002 Wilkins BJ, De Windt LJ, Bueno OF, Braz JC, Glascock BJ, Kimball TF, Molkentin JD. Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth. Molecular and Cellular Biology. 22: 7603-13. PMID 12370307 DOI: 10.1128/MCB.22.21.7603-7613.2002  0.84
2002 Wilkins BJ, Molkentin JD. Calcineurin and cardiac hypertrophy: where have we been? Where are we going? The Journal of Physiology. 541: 1-8. PMID 12015416 DOI: 10.1113/jphysiol.2002.017129  0.84
2002 Bueno OF, Wilkins BJ, Tymitz KM, Glascock BJ, Kimball TF, Lorenz JN, Molkentin JD. Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 4586-91. PMID 11904392 DOI: 10.1073/pnas.072647999  0.84
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