Raghu Kalluri - Publications

Affiliations: 
Harvard University, Cambridge, MA, United States 
Area:
Cell Biology

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 50: 547-549. PMID 30893584 DOI: 10.1016/j.immuni.2019.02.019  0.72
2018 Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. Plos Biology. 16: e2005907. PMID 30592710 DOI: 10.1371/journal.pbio.2005907  0.72
2018 Parchem JG, Kanasaki K, Kanasaki M, Sugimoto H, Xie L, Hamano Y, Lee SB, Gattone VH, Parry S, Strauss JF, Garovic VD, McElrath TF, Lu KH, Sibai BM, LeBleu VS, ... ... Kalluri R, et al. Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice. The Journal of Clinical Investigation. PMID 30179860 DOI: 10.1172/JCI99026  0.72
2018 Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Saur D, Kalluri R. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. Embo Molecular Medicine. PMID 30120146 DOI: 10.15252/emmm.201809085  0.72
2018 Eikesdal HP, Becker LM, Teng Y, Kizu A, Carstens JL, Kanasaki K, Sugimoto H, LeBleu VS, Kalluri R. BMP7 Signaling in TGFBR2-deficient Stromal Cells Provokes Epithelial Carcinogenesis. Molecular Cancer Research : McR. PMID 29934328 DOI: 10.1158/1541-7786.MCR-18-0120  0.72
2018 LeBleu VS, Kalluri R. A peek into cancer-associated fibroblasts: origins, functions and translational impact. Disease Models & Mechanisms. 11. PMID 29686035 DOI: 10.1242/dmm.029447  0.72
2018 Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR, Maitra A, Yee C, Rezvani K, Shpall E, ... ... Kalluri R, et al. Generation and testing of clinical-grade exosomes for pancreatic cancer. Jci Insight. 3. PMID 29669940 DOI: 10.1172/jci.insight.99263  0.72
2018 Jiao J, González Á, Stevenson HL, Gagea M, Sugimoto H, Kalluri R, Beretta L. Depletion of S100A4+ stromal cells does not prevent HCC development but reduces the stem cell-like phenotype of the tumors. Experimental & Molecular Medicine. 50: e422. PMID 29303514 DOI: 10.1038/emm.2017.175  0.32
2017 Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Ruivo CF, Melo SA, Lee JJ, Kalluri R. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. PMID 28607485 DOI: 10.1038/nature22341  0.72
2017 Carstens JL, Correa de Sampaio P, Yang D, Barua S, Wang H, Rao A, Allison JP, LeBleu VS, Kalluri R. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Nature Communications. 8: 15095. PMID 28447602 DOI: 10.1038/ncomms15095  0.72
2017 Kalluri R, LeBleu VS. Discovery of Double-Stranded Genomic DNA in Circulating Exosomes. Cold Spring Harbor Symposia On Quantitative Biology. PMID 28424339 DOI: 10.1101/sqb.2016.81.030932  0.72
2017 Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Detection of Mutant KRAS and TP53 DNA in Circulating Exosomes from Healthy Individuals and Patients with Pancreatic Cancer. Cancer Biology & Therapy. 0. PMID 28121262 DOI: 10.1080/15384047.2017.1281499  0.72
2016 Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, ... Kalluri R, et al. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. PMID 27089513 DOI: 10.1038/nm.4082  1
2015 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... Kalluri R, et al. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 28: 831-833. PMID 28843279 DOI: 10.1016/j.ccell.2015.11.002  0.72
2015 Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. Journal of Proteome Research. PMID 26595531 DOI: 10.1021/acs.jproteome.5b00675  1
2015 Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature. PMID 26560028 DOI: 10.1038/nature16064  1
2015 Lovisa S, LeBleu VS, Tampe B, Sugimoto H, Vadnagara K, Carstens JL, Wu CC, Hagos Y, Burckhardt BC, Pentcheva-Hoang T, Nischal H, Allison JP, Zeisberg M, Kalluri R. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nature Medicine. PMID 26236991 DOI: 10.1038/nm.3902  1
2015 Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. PMID 26106858 DOI: 10.1038/nature14581  1
2015 Léveillé N, Melo CA, Rooijers K, Díaz-Lagares A, Melo SA, Korkmaz G, Lopes R, Akbari Moqadam F, Maia AR, Wijchers PJ, Geeven G, den Boer ML, Kalluri R, de Laat W, Esteller M, et al. Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA. Nature Communications. 6: 6520. PMID 25813522 DOI: 10.1038/ncomms7520  1
2015 Zeisberg M, Kalluri R. Physiology of the Renal Interstitium. Clinical Journal of the American Society of Nephrology : Cjasn. PMID 25813241 DOI: 10.2215/CJN.00640114  1
2015 Zhang J, Jiao J, Cermelli S, Muir K, Jung KH, Zou R, Rashid A, Gagea M, Zabludoff S, Kalluri R, Beretta L. miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells. Cancer Research. 75: 1859-67. PMID 25769721 DOI: 10.1158/0008-5472.CAN-14-1254  1
2015 Tampe B, Tampe D, Zeisberg EM, Müller GA, Bechtel-Walz W, Koziolek M, Kalluri R, Zeisberg M. Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease. Ebiomedicine. 2: 19-36. PMID 25717475 DOI: 10.1016/j.ebiom.2014.11.005  1
2015 Keskin D, Kim J, Cooke VG, Wu CC, Sugimoto H, Gu C, De Palma M, Kalluri R, LeBleu VS. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Reports. 10: 1066-81. PMID 25704811 DOI: 10.1016/j.celrep.2015.01.035  1
2015 Xu X, Tan X, Tampe B, Nyamsuren G, Liu X, Maier LS, Sossalla S, Kalluri R, Zeisberg M, Hasenfuss G, Zeisberg EM. Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis. Cardiovascular Research. 105: 279-91. PMID 25616414 DOI: 10.1093/cvr/cvv015  1
2015 Xu X, Friehs I, Zhong Hu T, Melnychenko I, Tampe B, Alnour F, Iascone M, Kalluri R, Zeisberg M, Del Nido PJ, Zeisberg EM. Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition. Circulation Research. 116: 857-66. PMID 25587097 DOI: 10.1161/CIRCRESAHA.116.305629  1
2014 Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell. 26: 707-21. PMID 25446899 DOI: 10.1016/j.ccell.2014.09.005  1
2014 Miyake T, Kalluri R. Cardiac biology: Cell plasticity helps hearts to repair. Nature. 514: 575-6. PMID 25317554 DOI: 10.1038/nature13928  1
2014 LeBleu VS, O'Connell JT, Gonzalez Herrera KN, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Domingos Chinen LT, Rocha RM, Asara JM, Kalluri R. PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis. Nature Cell Biology. 16: 992-1003, 1-15. PMID 25241037 DOI: 10.1038/ncb3039  1
2014 Zeisberg M, Tampe B, LeBleu V, Tampe D, Zeisberg EM, Kalluri R. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. The American Journal of Pathology. 184: 2687-98. PMID 25111226 DOI: 10.1016/j.ajpath.2014.06.014  1
2014 Charytan DM, Padera R, Helfand AM, Zeisberg M, Xu X, Liu X, Himmelfarb J, Cinelli A, Kalluri R, Zeisberg EM. Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease. International Journal of Cardiology. 176: 99-109. PMID 25049013 DOI: 10.1016/j.ijcard.2014.06.062  1
2014 Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, ... ... Kalluri R, et al. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 25: 719-34. PMID 24856586 DOI: 10.1016/j.ccr.2014.04.005  1
2014 Ayala de la Peña F, Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R. Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. Plos One. 9: e95888. PMID 24760005 DOI: 10.1371/journal.pone.0095888  1
2014 Carstens JL, Lovisa S, Kalluri R. Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch. The Journal of Clinical Investigation. 124: 1458-60. PMID 24642461 DOI: 10.1172/JCI75239  1
2014 Tampe B, Tampe D, Müller CA, Sugimoto H, LeBleu V, Xu X, Müller GA, Zeisberg EM, Kalluri R, Zeisberg M. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. Journal of the American Society of Nephrology : Jasn. 25: 905-12. PMID 24480825 DOI: 10.1681/ASN.2013070723  1
2014 Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R. Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. The Journal of Biological Chemistry. 289: 3869-75. PMID 24398677 DOI: 10.1074/jbc.C113.532267  1
2013 Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nature Medicine. 19: 810-1. PMID 23836214 DOI: 10.1038/nm.3081  1
2013 LeBleu VS, Taduri G, O'Connell J, Teng Y, Cooke VG, Woda C, Sugimoto H, Kalluri R. Origin and function of myofibroblasts in kidney fibrosis. Nature Medicine. 19: 1047-53. PMID 23817022 DOI: 10.1038/nm.3218  1
2013 Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z. Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction. Proceedings of the National Academy of Sciences of the United States of America. 110: 11109-14. PMID 23776237 DOI: 10.1073/pnas.1309561110  1
2013 Zeisberg M, Kalluri R. The Kielin/chordin-like protein checkpoint constitutes a system of checks and balances in CKD. Journal of the American Society of Nephrology : Jasn. 24: 863-5. PMID 23687357 DOI: 10.1681/ASN.2013040412  1
2013 Duncan MB, Yang C, Tanjore H, Boyle PM, Keskin D, Sugimoto H, Zeisberg M, Olsen BR, Kalluri R. Type XVIII collagen is essential for survival during acute liver injury in mice. Disease Models & Mechanisms. 6: 942-51. PMID 23580202 DOI: 10.1242/dmm.011577  1
2013 Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. Journal of Molecular Medicine (Berlin, Germany). 91: 431-7. PMID 23519402 DOI: 10.1007/s00109-013-1020-6  1
2013 Brønnum H, Andersen DC, Schneider M, Sandberg MB, Eskildsen T, Nielsen SB, Kalluri R, Sheikh SP. miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. Plos One. 8: e56280. PMID 23441172 DOI: 10.1371/journal.pone.0056280  1
2013 Kanasaki K, Yu W, von Bodungen M, Larigakis JD, Kanasaki M, Ayala de la Pena F, Kalluri R, Hill WG. Loss of β1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1950-61. PMID 23395910 DOI: 10.1096/fj.12-223404  1
2013 Melo SA, Kalluri R. miR-29b moulds the tumour microenvironment to repress metastasis. Nature Cell Biology. 15: 139-40. PMID 23377028 DOI: 10.1038/ncb2684  1
2013 LeBleu VS, Teng Y, O'Connell JT, Charytan D, Müller GA, Müller CA, Sugimoto H, Kalluri R. Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nature Medicine. 19: 227-31. PMID 23353556 DOI: 10.1038/nm.2989  1
2013 Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH, LeBleu VS, Kalluri R. TGF-β1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. Journal of the American Society of Nephrology : Jasn. 24: 385-92. PMID 23274427 DOI: 10.1681/ASN.2012101031  1
2013 Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. eRNAs are required for p53-dependent enhancer activity and gene transcription. Molecular Cell. 49: 524-35. PMID 23273978 DOI: 10.1016/j.molcel.2012.11.021  1
2013 Zeisberg M, Kalluri R. Cellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis. American Journal of Physiology. Cell Physiology. 304: C216-25. PMID 23255577 DOI: 10.1152/ajpcell.00328.2012  1
2012 Kieran MW, Kalluri R, Cho YJ. The VEGF pathway in cancer and disease: responses, resistance, and the path forward. Cold Spring Harbor Perspectives in Medicine. 2: a006593. PMID 23209176 DOI: 10.1101/cshperspect.a006593  1
2012 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Reports. 2: 52-61. PMID 22840396 DOI: 10.1016/j.celrep.2012.06.002  1
2012 Melo SA, Kalluri R. Molecular pathways: microRNAs as cancer therapeutics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4234-9. PMID 22711704 DOI: 10.1158/1078-0432.CCR-11-2010  1
2012 Medici D, Kalluri R. Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype. Seminars in Cancer Biology. 22: 379-84. PMID 22554794 DOI: 10.1016/j.semcancer.2012.04.004  1
2012 Melo SA, Kalluri R. Angiogenesis is controlled by miR-27b associated with endothelial tip cells. Blood. 119: 2439-40. PMID 22422815 DOI: 10.1182/blood-2012-01-403642  1
2012 Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nature Medicine. 18: 396-404. PMID 22306733 DOI: 10.1038/nm.2629  1
2012 Ho DN, Kohler N, Sigdel A, Kalluri R, Morgan JR, Xu C, Sun S. Penetration of endothelial cell coated multicellular tumor spheroids by iron oxide nanoparticles. Theranostics. 2: 66-75. PMID 22272220 DOI: 10.7150/thno.3568  1
2012 Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 21: 66-81. PMID 22264789 DOI: 10.1016/j.ccr.2011.11.024  1
2011 Vong S, Kalluri R. The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis. Genes & Cancer. 2: 1139-45. PMID 22866205 DOI: 10.1177/1947601911423940  1
2011 LeBleu VS, Kalluri R. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney International. 80: 1119-21. PMID 22083636 DOI: 10.1038/ki.2011.300  1
2011 O'Connell JT, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, LeBleu VS, Dewar R, Rocha RM, Brentani RR, Resnick MB, Neilson EG, Zeisberg M, Kalluri R. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proceedings of the National Academy of Sciences of the United States of America. 108: 16002-7. PMID 21911392 DOI: 10.1073/pnas.1109493108  1
2011 De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, et al. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 20: 400-13. PMID 21907929 DOI: 10.1016/j.ccr.2011.08.014  1
2011 Charytan DM, Helfand AM, MacDonald BA, Cinelli A, Kalluri R, Zeisberg EM. Circulating endoglin concentration is not elevated in chronic kidney disease. Plos One. 6: e23718. PMID 21886815 DOI: 10.1371/journal.pone.0023718  1
2011 San Antonio JD, Schweitzer MH, Jensen ST, Kalluri R, Buckley M, Orgel JP. Dinosaur peptides suggest mechanisms of protein survival. Plos One. 6: e20381. PMID 21687667 DOI: 10.1371/journal.pone.0020381  1
2011 Tse JC, Kalluri R. Waking up dormant tumors. Breast Cancer Research : Bcr. 13: 310. PMID 21672272 DOI: 10.1186/bcr2872  1
2011 Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M, Lawler J, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proceedings of the National Academy of Sciences of the United States of America. 108: 9939-44. PMID 21622854 DOI: 10.1073/pnas.1105041108  1
2011 Medici D, Potenta S, Kalluri R. Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling. The Biochemical Journal. 437: 515-20. PMID 21585337 DOI: 10.1042/BJ20101500  1
2011 Ayala de la Peña F, Kanasaki K, Kanasaki M, Tangirala N, Maeda G, Kalluri R. Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma. The Journal of Biological Chemistry. 286: 20778-87. PMID 21388952 DOI: 10.1074/jbc.M110.198069  1
2011 Teng Y, Kanasaki K, Bardeesy N, Sugimoto H, Kalluri R. Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGFβ type II receptor independent manner. Biochemical and Biophysical Research Communications. 407: 633-9. PMID 21376704 DOI: 10.1016/j.bbrc.2011.02.142  1
2011 Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, ... ... Kalluri R, et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proceedings of the National Academy of Sciences of the United States of America. 108: 4394-9. PMID 21368194 DOI: 10.1073/pnas.1014720108  1
2011 Bravo-Nuevo A, Sugimoto H, Iyer S, Fallon Z, Lucas JM, Kazerounian S, Prendergast GC, Kalluri R, Shapiro NI, Benjamin LE. RhoB loss prevents streptozotocin-induced diabetes and ameliorates diabetic complications in mice. The American Journal of Pathology. 178: 245-52. PMID 21224061 DOI: 10.1016/j.ajpath.2010.11.040  1
2010 Lee SB, Kalluri R. Mechanistic connection between inflammation and fibrosis. Kidney International. Supplement. S22-6. PMID 21116313 DOI: 10.1038/ki.2010.418  1
2010 Zeisberg EM, Kalluri R. Origins of cardiac fibroblasts. Circulation Research. 107: 1304-12. PMID 21106947 DOI: 10.1161/CIRCRESAHA.110.231910  1
2010 Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. Conversion of vascular endothelial cells into multipotent stem-like cells. Nature Medicine. 16: 1400-6. PMID 21102460 DOI: 10.1038/nm.2252  1
2010 LeBleu V, Sund M, Sugimoto H, Birrane G, Kanasaki K, Finan E, Miller CA, Gattone VH, McLaughlin H, Shield CF, Kalluri R. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly. The Journal of Biological Chemistry. 285: 41874-85. PMID 20847057 DOI: 10.1074/jbc.M110.149534  1
2010 Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, et al. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 122: 1130-3. PMID 20837938 DOI: 10.1161/CIRCULATIONAHA.110.950089  1
2010 Wiig H, Keskin D, Kalluri R. Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biology : Journal of the International Society For Matrix Biology. 29: 645-56. PMID 20727409 DOI: 10.1016/j.matbio.2010.08.001  1
2010 Keskin D, Kalluri R. NF-kappaB-induced chromatin remodeling regulates angiogenesis. Blood. 116: 312-3. PMID 20651081 DOI: 10.1182/blood-2010-03-274316  1
2010 Nataraj D, Ernst A, Kalluri R. Idiopathic pulmonary fibrosis is associated with endothelial to mesenchymal transition. American Journal of Respiratory Cell and Molecular Biology. 43: 129-30. PMID 20651063 DOI: 10.1165/rcmb.2010-0044ED  1
2010 Shenoy V, Kanasaki K, Kalluri R. Pre-eclampsia: connecting angiogenic and metabolic pathways. Trends in Endocrinology and Metabolism: Tem. 21: 529-36. PMID 20646932 DOI: 10.1016/j.tem.2010.05.002  1
2010 Krenning G, Zeisberg EM, Kalluri R. The origin of fibroblasts and mechanism of cardiac fibrosis. Journal of Cellular Physiology. 225: 631-7. PMID 20635395 DOI: 10.1002/jcp.22322  1
2010 Hamano Y, Okude T, Shirai R, Sato I, Kimura R, Ogawa M, Ueda Y, Yokosuka O, Kalluri R, Ueda S. Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. Journal of the American Society of Nephrology : Jasn. 21: 1445-55. PMID 20616167 DOI: 10.1681/ASN.2009050492  1
2010 Polyak K, Kalluri R. The role of the microenvironment in mammary gland development and cancer. Cold Spring Harbor Perspectives in Biology. 2: a003244. PMID 20591988 DOI: 10.1101/cshperspect.a003244  1
2010 Bechtel W, McGoohan S, Zeisberg EM, Müller GA, Kalbacher H, Salant DJ, Müller CA, Kalluri R, Zeisberg M. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nature Medicine. 16: 544-50. PMID 20418885 DOI: 10.1038/nm.2135  1
2010 Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. The Journal of Biological Chemistry. 285: 20202-12. PMID 20363741 DOI: 10.1074/jbc.M110.102012  1
2010 Lee SB, Wong AP, Kanasaki K, Xu Y, Shenoy VK, McElrath TF, Whitesides GM, Kalluri R. Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions. The American Journal of Pathology. 176: 710-20. PMID 20075204 DOI: 10.2353/ajpath.2010.090513  1
2010 Hertig A, Gangadhar T, Kalluri R. Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease. Journal of Molecular and Cellular Cardiology. 48: 497-503. PMID 19646990 DOI: 10.1016/j.yjmcc.2009.07.022  1
2009 LeBleu V, Sugimoto H, Mundel TM, Gerami-Naini B, Finan E, Miller CA, Gattone VH, Lu L, Shield CF, Folkman J, Kalluri R. Stem cell therapies benefit Alport syndrome. Journal of the American Society of Nephrology : Jasn. 20: 2359-70. PMID 19833902 DOI: 10.1681/ASN.2009010123  1
2009 Kizu A, Medici D, Kalluri R. Endothelial-mesenchymal transition as a novel mechanism for generating myofibroblasts during diabetic nephropathy. The American Journal of Pathology. 175: 1371-3. PMID 19729485 DOI: 10.2353/ajpath.2009.090698  1
2009 Duncan MB, Kalluri R. Parstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis. Molecular Interventions. 9: 168-70. PMID 19720748 DOI: 10.1124/mi.9.4.4  1
2009 Kanasaki K, Kalluri R. The biology of preeclampsia. Kidney International. 76: 831-7. PMID 19657323 DOI: 10.1038/ki.2009.284  1
2009 Romagnani P, Kalluri R. Possible mechanisms of kidney repair. Fibrogenesis & Tissue Repair. 2: 3. PMID 19558670 DOI: 10.1186/1755-1536-2-3  1
2009 Lee SB, Kanasaki K, Kalluri R. Circulating TGF-beta1 as a reliable biomarker for chronic kidney disease progression in the African-American population. Kidney International. 76: 10-2. PMID 19528989 DOI: 10.1038/ki.2009.130  1
2009 Eikesdal HP, Kalluri R. Drug resistance associated with antiangiogenesis therapy. Seminars in Cancer Biology. 19: 310-7. PMID 19524042 DOI: 10.1016/j.semcancer.2009.05.006  1
2009 Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. The Journal of Clinical Investigation. 119: 1420-8. PMID 19487818 DOI: 10.1172/JCI39104  1
2009 Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. The Journal of Clinical Investigation. 119: 1417-9. PMID 19487817 DOI: 10.1172/JCI39675  1
2009 Sohn RL, Huang P, Kawahara G, Mitchell M, Guyon J, Kalluri R, Kunkel LM, Gussoni E. A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion. Proceedings of the National Academy of Sciences of the United States of America. 106: 9274-9. PMID 19470472 DOI: 10.1073/pnas.0904398106  1
2009 Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Research. 69: 4537-44. PMID 19435903 DOI: 10.1158/0008-5472.CAN-08-4539  1
2009 Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, et al. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science (New York, N.Y.). 324: 626-31. PMID 19407199 DOI: 10.1126/science.1165069  1
2009 Sund M, Kalluri R. Tumor stroma derived biomarkers in cancer. Cancer Metastasis Reviews. 28: 177-83. PMID 19259624 DOI: 10.1007/s10555-008-9175-2  1
2008 Zavadil J, Haley J, Kalluri R, Muthuswamy SK, Thompson E. Epithelial-mesenchymal transition. Cancer Research. 68: 9574-7. PMID 19047131 DOI: 10.1158/0008-5472.CAN-08-2316  1
2008 Cooke VG, Kalluri R. Chapter 1. Molecular mechanism of type IV collagen-derived endogenous inhibitors of angiogenesis. Methods in Enzymology. 444: 1-19. PMID 19007658 DOI: 10.1016/S0076-6879(08)02801-2  1
2008 Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. Journal of the American Society of Nephrology : Jasn. 19: 2282-7. PMID 18987304 DOI: 10.1681/ASN.2008050513  1
2008 Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity. Proceedings of the National Academy of Sciences of the United States of America. 105: 15040-5. PMID 18818312 DOI: 10.1073/pnas.0807055105  1
2008 Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R. Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Experimental Cell Research. 314: 3292-305. PMID 18775695 DOI: 10.1016/j.yexcr.2008.08.011  1
2008 LeBleu VS, Kalluri R. Stem cell-based therapy for glomerular diseases: an evolving concept. Journal of the American Society of Nephrology : Jasn. 19: 1621-3. PMID 18701605 DOI: 10.1681/ASN.2008070735  1
2008 Kalluri R, Han Y. Targeting TGF-beta and the extracellular matrix in Marfan's syndrome. Developmental Cell. 15: 1-2. PMID 18606132 DOI: 10.1016/j.devcel.2008.06.005  1
2008 Zeisberg M, Kalluri R. Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis. Frontiers in Bioscience : a Journal and Virtual Library. 13: 6991-8. PMID 18508710 DOI: 10.2741/3204  1
2008 Nyberg P, Salo T, Kalluri R. Tumor microenvironment and angiogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 13: 6537-53. PMID 18508679 DOI: 10.2741/3173  1
2008 Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, Parry S, Augustin HG, Gattone VH, Folkman J, Strauss JF, Kalluri R. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature. 453: 1117-21. PMID 18469803 DOI: 10.1038/nature06951  1
2008 Zeisberg M, Kalluri R. Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Pediatric Nephrology (Berlin, Germany). 23: 1395-8. PMID 18446379 DOI: 10.1007/s00467-008-0818-x  1
2008 Kalluri R, Kanasaki K. RNA interference: generic block on angiogenesis. Nature. 452: 543-5. PMID 18385725 DOI: 10.1038/452543a  1
2008 Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Experimental Biology and Medicine (Maywood, N.J.). 233: 155-62. PMID 18222970 DOI: 10.3181/0706-RM-167  1
2008 Lebleu VS, Sugimoto H, Miller CA, Gattone VH, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 284-92. PMID 18180701 DOI: 10.1038/labinvest.3700715  1
2008 Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, ... ... Kalluri R, et al. Modification of kidney barrier function by the urokinase receptor. Nature Medicine. 14: 55-63. PMID 18084301 DOI: 10.1038/nm1696  1
2008 Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Developmental Biology. 313: 584-93. PMID 18082680 DOI: 10.1016/j.ydbio.2007.10.047  1
2008 Mundel TM, Yliniemi AM, Maeshima Y, Sugimoto H, Kieran M, Kalluri R. Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6(IV)NC1) inhibits angiogenesis and tumor growth. International Journal of Cancer. Journal International Du Cancer. 122: 1738-44. PMID 18074349 DOI: 10.1002/ijc.23269  1
2008 Tanjore H, Zeisberg EM, Gerami-Naini B, Kalluri R. Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 75-82. PMID 18058911 DOI: 10.1002/dvdy.21385  1
2007 Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Research. 67: 10123-8. PMID 17974953 DOI: 10.1158/0008-5472.CAN-07-3127  1
2007 LeBleu VS, Macdonald B, Kalluri R. Structure and function of basement membranes. Experimental Biology and Medicine (Maywood, N.J.). 232: 1121-9. PMID 17895520 DOI: 10.3181/0703-MR-72  1
2007 Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nature Medicine. 13: 952-61. PMID 17660828 DOI: 10.1038/nm1613  1
2007 Mundel TM, Kalluri R. Type IV collagen-derived angiogenesis inhibitors. Microvascular Research. 74: 85-9. PMID 17602710 DOI: 10.1016/j.mvr.2007.05.005  1
2007 Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. The Journal of Biological Chemistry. 282: 23337-47. PMID 17562716 DOI: 10.1074/jbc.M700194200  1
2007 Sugimoto H, Grahovac G, Zeisberg M, Kalluri R. Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. Diabetes. 56: 1825-33. PMID 17456853 DOI: 10.2337/db06-1226  1
2007 Teng Y, Zeisberg M, Kalluri R. Transcriptional regulation of epithelial-mesenchymal transition. The Journal of Clinical Investigation. 117: 304-6. PMID 17273552 DOI: 10.1172/JCI31200  1
2007 Garovic VD, Wagner SJ, Petrovic LM, Gray CE, Hall P, Sugimoto H, Kalluri R, Grande JP. Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 22: 1136-43. PMID 17255128 DOI: 10.1093/ndt/gfl711  1
2007 Tse JC, Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. Journal of Cellular Biochemistry. 101: 816-29. PMID 17243120 DOI: 10.1002/jcb.21215  1
2007 Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, et al. Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse. The American Journal of Pathology. 170: 110-25. PMID 17200187 DOI: 10.2353/ajpath.2007.060158  1
2007 Sugimoto H, Yang C, LeBleu VS, Soubasakos MA, Giraldo M, Zeisberg M, Kalluri R. BMP-7 functions as a novel hormone to facilitate liver regeneration. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 256-64. PMID 17116741 DOI: 10.1096/fj.06-6837com  1
2007 Dandapani SV, Sugimoto H, Matthews BD, Kolb RJ, Sinha S, Gerszten RE, Zhou J, Ingber DE, Kalluri R, Pollak MR. Alpha-actinin-4 is required for normal podocyte adhesion. The Journal of Biological Chemistry. 282: 467-77. PMID 17082197 DOI: 10.1074/jbc.M605024200  1
2006 Sugimoto H, Mundel TM, Kieran MW, Kalluri R. Identification of fibroblast heterogeneity in the tumor microenvironment. Cancer Biology & Therapy. 5: 1640-6. PMID 17106243  1
2006 Kalluri R, Zeisberg E. Controlling angiogenesis in heart valves. Nature Medicine. 12: 1118-9. PMID 17024200 DOI: 10.1038/nm1006-1118  1
2006 Kalluri R. Proteinuria with and without renal glomerular podocyte effacement. Journal of the American Society of Nephrology : Jasn. 17: 2383-9. PMID 16914535 DOI: 10.1681/ASN.2006060628  1
2006 Farazi PA, Zeisberg M, Glickman J, Zhang Y, Kalluri R, DePinho RA. Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice. Cancer Research. 66: 6622-7. PMID 16818635 DOI: 10.1158/0008-5472.CAN-05-4609  1
2006 Sugimoto H, Mundel TM, Sund M, Xie L, Cosgrove D, Kalluri R. Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 7321-6. PMID 16648256 DOI: 10.1073/pnas.0601436103  1
2006 Kalluri R, Zeisberg M. Fibroblasts in cancer. Nature Reviews. Cancer. 6: 392-401. PMID 16572188 DOI: 10.1038/nrc1877  1
2006 Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. The Journal of Cell Biology. 172: 973-81. PMID 16567498 DOI: 10.1083/jcb.200601018  1
2006 Zeisberg M, Khurana M, Rao VH, Cosgrove D, Rougier JP, Werner MC, Shield CF, Werb Z, Kalluri R. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. Plos Medicine. 3: e100. PMID 16509766 DOI: 10.1371/journal.pmed.0030100  1
2006 Tanjore H, Kalluri R. The role of type IV collagen and basement membranes in cancer progression and metastasis. The American Journal of Pathology. 168: 715-7. PMID 16507886 DOI: 10.2353/ajpath.2006.051321  1
2006 Zeisberg M, Kramer K, Sindhi N, Sarkar P, Upton M, Kalluri R. De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane. Molecular and Cellular Biochemistry. 283: 181-9. PMID 16444601 DOI: 10.1007/s11010-006-2677-8  1
2006 Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP. Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. The Journal of Biological Chemistry. 281: 6020-9. PMID 16365041 DOI: 10.1074/jbc.M509134200  1
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