Ananda W. Goldrath - Publications

Biology University of California, San Diego, La Jolla, CA 
Cell Biology

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Russ BE, Barugahare A, Dakle P, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, See M, Nussing S, Morey AE, Udupa VA, ... ... Goldrath AW, et al. Active maintenance of CD8 T cell naivety through regulation of global genome architecture. Cell Reports. 42: 113301. PMID 37858463 DOI: 10.1016/j.celrep.2023.113301  0.529
2023 Reina-Campos M, Heeg M, Kennewick K, Mathews IT, Galletti G, Luna V, Nguyen Q, Huang H, Milner JJ, Hu KH, Vichaidit A, Santillano N, Boland BS, Chang JT, Jain M, ... ... Goldrath AW, et al. Metabolic programs of T cell tissue residency empower tumour immunity. Nature. PMID 37648857 DOI: 10.1038/s41586-023-06483-w  0.562
2023 Heeg M, Goldrath AW. Insights into phenotypic and functional CD8 T heterogeneity. Immunological Reviews. PMID 37191051 DOI: 10.1111/imr.13218  0.547
2023 Nguyen QP, Takehara KK, Deng TZ, O'Shea S, Heeg M, Omilusik KD, Milner JJ, Quon S, Pipkin ME, Choi J, Crotty S, Goldrath AW. Transcriptional programming of CD4 T differentiation in viral infection balances effector- and memory-associated gene expression. Science Immunology. 8: eabq7486. PMID 37172104 DOI: 10.1126/sciimmunol.abq7486  0.546
2023 Getzler AJ, Frederick MA, Milner JJ, Venables T, Diao H, Toma C, Nagaraja SD, Albao DS, Bélanger S, Tsuda SM, Kim J, Crotty S, Goldrath AW, Pipkin ME. Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8 T stem cell memory. Biorxiv : the Preprint Server For Biology. PMID 37090503 DOI: 10.1101/2023.01.18.524461  0.543
2023 Quon S, Yu B, Russ BE, Tsyganov K, Nguyen H, Toma C, Heeg M, Hocker JD, Milner JJ, Crotty S, Pipkin ME, Turner SJ, Goldrath AW. DNA architectural protein CTCF facilitates subset-specific chromatin interactions to limit the formation of memory CD8 T cells. Immunity. PMID 37040762 DOI: 10.1016/j.immuni.2023.03.017  0.534
2023 Russ BE, Tsyganov K, Quon S, Yu B, Li J, Lee JKC, Olshansky M, He Z, Harrison PF, Barugahare A, See M, Nussing S, Morey AE, Udupa VA, Bennett TJ, ... ... Goldrath AW, et al. Active maintenance of CD8 T cell naïvety through regulation of global genome architecture. Biorxiv : the Preprint Server For Biology. PMID 36909629 DOI: 10.1101/2023.02.26.530139  0.496
2023 Heeg M, Goldrath AW. License to kill: Retinoic acid programs T cells for tissue residency. The Journal of Experimental Medicine. 220. PMID 36897330 DOI: 10.1084/jem.20230161  0.383
2022 Lin YH, Duong HG, Limary AE, Kim ES, Hsu P, Patel SA, Wong WH, Indralingam CS, Liu YC, Yao P, Chiang NR, Vandenburgh SA, Anderson TR, Olvera JG, Ferry A, ... ... Goldrath AW, et al. Small intestine and colon tissue-resident memory CD8 T cells exhibit molecular heterogeneity and differential dependence on Eomes. Immunity. PMID 36580919 DOI: 10.1016/j.immuni.2022.12.007  0.539
2022 Liu C, Omilusik K, Toma C, Kurd NS, Chang JT, Goldrath AW, Wang W. Systems-level identification of key transcription factors in immune cell specification. Plos Computational Biology. 18: e1010116. PMID 36156073 DOI: 10.1371/journal.pcbi.1010116  0.496
2022 Shaw LA, Deng TZ, Omilusik KD, Takehara KK, Nguyen QP, Goldrath AW. Id3 expression identifies CD4 memory Th1 cells. Proceedings of the National Academy of Sciences of the United States of America. 119: e2204254119. PMID 35858332 DOI: 10.1073/pnas.2204254119  0.58
2022 Crowl JT, Heeg M, Ferry A, Milner JJ, Omilusik KD, Toma C, He Z, Chang JT, Goldrath AW. Tissue-resident memory CD8 T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments. Nature Immunology. PMID 35761084 DOI: 10.1038/s41590-022-01229-8  0.549
2022 Zemmour D, Goldrath A, Kronenberg M, Kang J, Benoist C. The ImmGen consortium OpenSource T cell project. Nature Immunology. 23: 643-644. PMID 35469020 DOI: 10.1038/s41590-022-01197-z  0.347
2021 Francis JM, Leistritz-Edwards D, Dunn A, Tarr C, Lehman J, Dempsey C, Hamel A, Rayon V, Liu G, Wang Y, Wille M, Durkin M, Hadley K, Sheena A, Roscoe B, ... ... Goldrath AW, et al. Allelic variation in class I HLA determines CD8 T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2. Science Immunology. eabk3070. PMID 34793243 DOI: 10.1126/sciimmunol.abk3070  0.446
2021 Omilusik KD, Nadjsombati MS, Yoshida TM, Shaw LA, Goulding J, Goldrath AW. Ubiquitin Specific Protease 1 Expression and Function in T Cell Immunity. Journal of Immunology (Baltimore, Md. : 1950). PMID 34380645 DOI: 10.4049/jimmunol.2100303  0.591
2021 Milner JJ, Toma C, Quon S, Omilusik K, Scharping NE, Dey A, Reina-Campos M, Nguyen H, Getzler AJ, Diao H, Yu B, Delpoux A, Yoshida TM, Li D, Qi J, ... ... Goldrath AW, et al. Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection. The Journal of Experimental Medicine. 218. PMID 34037670 DOI: 10.1084/jem.20202512  0.572
2021 Reina-Campos M, Scharping NE, Goldrath AW. CD8 T cell metabolism in infection and cancer. Nature Reviews. Immunology. PMID 33981085 DOI: 10.1038/s41577-021-00537-8  0.505
2021 Liikanen I, Lauhan C, Quon S, Omilusik K, Phan AT, Bartrolí LB, Ferry A, Goulding J, Chen J, Scott-Browne JP, Yustein JT, Scharping NE, Witherden DA, Goldrath AW. Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. The Journal of Clinical Investigation. 131. PMID 33792560 DOI: 10.1172/JCI143729  0.478
2020 Milner JJ, Nguyen H, Omilusik K, Reina-Campos M, Tsai M, Toma C, Delpoux A, Boland BS, Hedrick SM, Chang JT, Goldrath AW. Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population. Proceedings of the National Academy of Sciences of the United States of America. PMID 32978300 DOI: 10.1073/pnas.2008571117  0.549
2020 Boland BS, He Z, Tsai MS, Olvera JG, Omilusik KD, Duong HG, Kim ES, Limary AE, Jin W, Milner JJ, Yu B, Patel SA, Louis TL, Tysl T, Kurd NS, ... ... Goldrath AW, et al. Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses. Science Immunology. 5. PMID 32826341 DOI: 10.1126/Sciimmunol.Abb4432  0.597
2020 Choi J, Diao H, Faliti CE, Truong J, Rossi M, Bélanger S, Yu B, Goldrath AW, Pipkin ME, Crotty S. Bcl-6 is the nexus transcription factor of T follicular helper cells via repressor-of-repressor circuits. Nature Immunology. PMID 32572238 DOI: 10.1038/S41590-020-0706-5  0.58
2020 Milner JJ, Toma C, He Z, Kurd NS, Nguyen QP, McDonald B, Quezada L, Widjaja CE, Witherden DA, Crowl JT, Shaw LA, Yeo GW, Chang JT, Omilusik KD, Goldrath AW. Heterogenous Populations of Tissue-Resident CD8 T Cells Are Generated in Response to Infection and Malignancy. Immunity. 52: 808-824.e7. PMID 32433949 DOI: 10.1016/J.Immuni.2020.04.007  0.608
2020 Kurd NS, He Z, Louis TL, Milner JJ, Omilusik KD, Jin W, Tsai MS, Widjaja CE, Kanbar JN, Olvera JG, Tysl T, Quezada LK, Boland BS, Huang WJ, Murre C, ... Goldrath AW, et al. Early precursors and molecular determinants of tissue-resident memory CD8 T lymphocytes revealed by single-cell RNA sequencing. Science Immunology. 5. PMID 32414833 DOI: 10.1126/Sciimmunol.Aaz6894  0.631
2020 Lauhan CR, Witherden D, Liikanan I, Goldrath A. Abstract A10: Constitutive HIF activity enhances T-cell antitumor immunity and memory T-cell formation in the murine adoptive cell therapy model Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-A10  0.542
2019 Reina-Campos M, Goldrath AW. Antitumour T cells stand the test of time. Nature. 576: 392-393. PMID 31844255 DOI: 10.1038/D41586-019-03731-W  0.49
2019 Omilusik KD, Goldrath AW. Remembering to remember: T cell memory maintenance and plasticity. Current Opinion in Immunology. 58: 89-97. PMID 31170601 DOI: 10.1016/J.Coi.2019.04.009  0.631
2019 Stone SL, Peel JN, Scharer CD, Risley CA, Chisolm DA, Schultz MD, Yu B, Ballesteros-Tato A, Wojciechowski W, Mousseau B, Misra RS, Hanidu A, Jiang H, Qi Z, Boss JM, ... ... Goldrath AW, et al. T-bet Transcription Factor Promotes Antibody-Secreting Cell Differentiation by Limiting the Inflammatory Effects of IFN-γ on B Cells. Immunity. PMID 31076359 DOI: 10.1016/J.Immuni.2019.04.004  0.507
2019 Nguyen QP, Deng T, Witherden DA, Goldrath AW. Origins of CD4 circulating and tissue-resident memory T cells. Immunology. PMID 30897205 DOI: 10.1111/Imm.13059  0.647
2018 Smith-Raska MR, Arenzana TL, D'Cruz LM, Khodadadi-Jamayran A, Tsirigos A, Goldrath AW, Reizis B. The Transcription Factor Zfx Regulates Peripheral T Cell Self-Renewal and Proliferation. Frontiers in Immunology. 9: 1482. PMID 30022979 DOI: 10.3389/Fimmu.2018.01482  0.597
2018 Wang D, Diao H, Getzler AJ, Rogal W, Frederick MA, Milner J, Yu B, Crotty S, Goldrath AW, Pipkin ME. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 48: 659-674.e6. PMID 29669249 DOI: 10.1016/J.Immuni.2018.03.028  0.598
2018 Milner JJ, Goldrath AW. Transcriptional programming of tissue-resident memory CD8 T cells. Current Opinion in Immunology. 51: 162-169. PMID 29621697 DOI: 10.1016/J.Coi.2018.03.017  0.597
2018 Omilusik KD, Nadjsombati MS, Shaw LA, Yu B, Milner JJ, Goldrath AW. Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8T cells. The Journal of Experimental Medicine. PMID 29440362 DOI: 10.1084/Jem.20171584  0.654
2018 Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW. Erratum: Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. PMID 29320476 DOI: 10.1038/Nature25445  0.481
2018 Goldrath A. Transcriptional Control of Memory T Cell Differentiation Blood. 132. DOI: 10.1182/Blood-2018-99-109536  0.56
2017 Omilusik KD, Goldrath AW. The origins of memory T cells. Nature. 552: 337-339. PMID 32080617 DOI: 10.1038/D41586-017-08280-8  0.587
2017 Omilusik KD, Goldrath AW. The origins of memory T cells. Nature. 552: 337-339. PMID 29293221 DOI: 10.1038/d41586-017-08280-8  0.48
2017 Delpoux A, Michelini RH, Verma S, Lai CY, Omilusik KD, Utzschneider DT, Redwood AJ, Goldrath AW, Benedict CA, Hedrick SM. Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells. The Journal of Experimental Medicine. PMID 29282254 DOI: 10.1084/Jem.20170697  0.631
2017 Milner JJ, Toma C, Yu B, Zhang K, Omilusik K, Phan AT, Wang D, Getzler AJ, Nguyen T, Crotty S, Wang W, Pipkin ME, Goldrath AW. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours. Nature. 552: 253-257. PMID 29211713 DOI: 10.1038/Nature24993  0.621
2017 Palazon A, Tyrakis PA, Macias D, Veliça P, Rundqvist H, Fitzpatrick S, Vojnovic N, Phan AT, Loman N, Hedenfalk I, Hatschek T, Lövrot J, Foukakis T, Goldrath AW, Bergh J, et al. An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression. Cancer Cell. 32: 669-683.e5. PMID 29136509 DOI: 10.1016/J.Ccell.2017.10.003  0.488
2017 Widjaja CE, Olvera JG, Metz PJ, Phan AT, Savas JN, de Bruin G, Leestemaker Y, Berkers CR, de Jong A, Florea BI, Fisch K, Lopez J, Kim SH, Garcia DA, Searles S, ... ... Goldrath AW, et al. Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. The Journal of Clinical Investigation. PMID 28846070 DOI: 10.1172/Jci90895  0.643
2017 Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. Erratum: Epigenetic landscapes reveal transcription factors that regulate CD8(+) T cell differentiation. Nature Immunology. 18: 705. PMID 28518161 DOI: 10.1038/ni0617-705b  0.482
2017 Phan AT, Goldrath AW, Glass CK. Metabolic and Epigenetic Coordination of T Cell and Macrophage Immunity. Immunity. 46: 714-729. PMID 28514673 DOI: 10.1016/J.Immuni.2017.04.016  0.481
2017 Yu B, Zhang K, Milner JJ, Toma C, Chen R, Scott-Browne JP, Pereira RM, Crotty S, Chang JT, Pipkin ME, Wang W, Goldrath AW. Epigenetic landscapes reveal transcription factors that regulate CD8(+) T cell differentiation. Nature Immunology. PMID 28288100 DOI: 10.1038/Ni.3706  0.654
2017 Kakaradov B, Arsenio J, Widjaja CE, He Z, Aigner S, Metz PJ, Yu B, Wehrens EJ, Lopez J, Kim SH, Zuniga EI, Goldrath AW, Chang JT, Yeo GW. Early transcriptional and epigenetic regulation of CD8(+) T cell differentiation revealed by single-cell RNA sequencing. Nature Immunology. PMID 28218746 DOI: 10.1038/Ni.3688  0.601
2016 Phan AT, Doedens AL, Palazon A, Tyrakis PA, Cheung KP, Johnson RS, Goldrath AW. Constitutive Glycolytic Metabolism Supports CD8(+) T Cell Effector Memory Differentiation during Viral Infection. Immunity. PMID 27836431 DOI: 10.1016/J.Immuni.2016.10.017  0.794
2016 Tyrakis PA, Palazon A, Macias D, Lee KL, Phan AT, Veliça P, You J, Chia GS, Sim J, Doedens A, Abelanet A, Evans CE, Griffiths JR, Poellinger L, Goldrath AW, et al. S-2-hydroxyglutarate regulates CD8(+) T-lymphocyte fate. Nature. PMID 27798602 DOI: 10.1038/Nature20165  0.506
2016 Clever D, Roychoudhuri R, Constantinides MG, Askenase MH, Sukumar M, Klebanoff CA, Eil RL, Hickman HD, Yu Z, Pan JH, Palmer DC, Phan AT, Goulding J, Gattinoni L, Goldrath AW, et al. Oxygen Sensing by T Cells Establishes an Immunologically Tolerant Metastatic Niche. Cell. 166: 1117-1131.e14. PMID 27565342 DOI: 10.1016/J.Cell.2016.07.032  0.515
2016 Doedens AL, Rubinstein MP, Gross ET, Best JA, Craig DH, Baker MK, Cole DJ, Bui JD, Goldrath AW. Molecular programming of tumor-infiltrating CD8+ T cells and IL15 resistance. Cancer Immunology Research. PMID 27485135 DOI: 10.1158/2326-6066.CIR-15-0178  0.448
2016 Shaw LA, Bélanger S, Omilusik KD, Cho S, Scott-Browne JP, Nance JP, Goulding J, Lasorella A, Lu LF, Crotty S, Goldrath AW. Id2 reinforces TH1 differentiation and inhibits E2A to repress TFH differentiation. Nature Immunology. PMID 27213691 DOI: 10.1038/Ni.3461  0.568
2016 Stradner MH, Cheung KP, Lasorella A, Goldrath AW, D'Cruz LM. Id2 regulates hypo-responsive invariant Natural Killer T cells. Immunology and Cell Biology. PMID 26880074 DOI: 10.1038/Icb.2016.19  0.771
2016 Chea S, Schmutz S, Berthault C, Perchet T, Petit M, Burlen-Defranoux O, Goldrath AW, Rodewald HR, Cumano A, Golub R. Single-Cell Gene Expression Analyses Reveal Heterogeneous Responsiveness of Fetal Innate Lymphoid Progenitors to Notch Signaling. Cell Reports. 14: 1500-16. PMID 26832410 DOI: 10.1016/J.Celrep.2016.01.015  0.511
2016 Almaden JV, Liu YC, Yang E, Otero D, Birnbaum H, Davis-Turak J, Asagiri M, David M, Goldrath AW, Hoffmann A. B cell survival and development controlled by the coordination of NFκB family members RelB and cRel. Blood. PMID 26773039 DOI: 10.1182/Blood-2014-10-606988  0.361
2015 Su EW, Moore CJ, Suriano S, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Andrijauskaite K, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li Z, Cole DJ, et al. IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy. Science Translational Medicine. 7: 311ra170. PMID 26511507 DOI: 10.1126/Scitranslmed.Aac8155  0.343
2015 Omilusik KD, Best JA, Yu B, Goossens S, Weidemann A, Nguyen JV, Seuntjens E, Stryjewska A, Zweier C, Roychoudhuri R, Gattinoni L, Bird LM, Higashi Y, Kondoh H, Huylebroeck D, ... ... Goldrath AW, et al. Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection. The Journal of Experimental Medicine. PMID 26503445 DOI: 10.1084/Jem.20150194  0.656
2015 Phan AT, Goldrath AW. Hypoxia-inducible factors regulate T cell metabolism and function. Molecular Immunology. PMID 26298577 DOI: 10.1016/J.Molimm.2015.08.004  0.492
2015 Stone EL, Pepper M, Katayama CD, Kerdiles YM, Lai CY, Emslie E, Lin YC, Yang E, Goldrath AW, Li MO, Cantrell DA, Hedrick SM. ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation. Immunity. 42: 239-51. PMID 25692700 DOI: 10.1016/J.Immuni.2015.01.017  0.538
2015 Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, ... ... Goldrath AW, et al. ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling. Nature Communications. 6: 5794. PMID 25565005 DOI: 10.1038/Ncomms6794  0.483
2015 Fulton RB, Hamilton SE, Xing Y, Best JA, Goldrath AW, Hogquist KA, Jameson SC. The TCR's sensitivity to self peptide-MHC dictates the ability of naive CD8(+) T cells to respond to foreign antigens. Nature Immunology. 16: 107-17. PMID 25419629 DOI: 10.1038/Ni.3043  0.529
2014 Chang JT, Wherry EJ, Goldrath AW. Molecular regulation of effector and memory T cell differentiation. Nature Immunology. 15: 1104-15. PMID 25396352 DOI: 10.1038/Ni.3031  0.592
2014 Palazon A, Goldrath AW, Nizet V, Johnson RS. HIF transcription factors, inflammation, and immunity. Immunity. 41: 518-28. PMID 25367569 DOI: 10.1016/J.Immuni.2014.09.008  0.405
2014 D'Cruz LM, Stradner MH, Yang CY, Goldrath AW. E and Id proteins influence invariant NKT cell sublineage differentiation and proliferation. Journal of Immunology (Baltimore, Md. : 1950). 192: 2227-36. PMID 24470501 DOI: 10.4049/Jimmunol.1302904  0.664
2014 Rong Z, Wang M, Hu Z, Stradner M, Zhu S, Kong H, Yi H, Goldrath A, Yang YG, Xu Y, Fu X. An effective approach to prevent immune rejection of human ESC-derived allografts. Cell Stem Cell. 14: 121-30. PMID 24388175 DOI: 10.1016/J.Stem.2013.11.014  0.44
2014 Stradner MH, D’Cruz LM, Yang CY, Goldrath AW. A8.23 E and Id proteins influence invariant Natural Killer T cell sublineage differentiation and proliferation Annals of the Rheumatic Diseases. 73. DOI: 10.1136/Annrheumdis-2013-205124.197  0.677
2013 Rubinstein MP, Salem ML, Doedens AL, Moore CJ, Chiuzan C, Rivell GL, Cole DJ, Goldrath AW. G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. Journal of Hematology & Oncology. 6: 75. PMID 24279871 DOI: 10.1186/1756-8722-6-75  0.406
2013 Omilusik KD, Shaw LA, Goldrath AW. Remembering one's ID/E-ntity: E/ID protein regulation of T cell memory. Current Opinion in Immunology. 25: 660-6. PMID 24094885 DOI: 10.1016/J.Coi.2013.09.004  0.676
2013 Doedens AL, Phan AT, Stradner MH, Fujimoto JK, Nguyen JV, Yang E, Johnson RS, Goldrath AW. Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen. Nature Immunology. 14: 1173-82. PMID 24076634 DOI: 10.1038/Ni.2714  0.494
2013 Saenz SA, Siracusa MC, Monticelli LA, Ziegler CG, Kim BS, Brestoff JR, Peterson LW, Wherry EJ, Goldrath AW, Bhandoola A, Artis D. IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells. The Journal of Experimental Medicine. 210: 1823-37. PMID 23960191 DOI: 10.1084/Jem.20122332  0.443
2013 Hess Michelini R, Doedens AL, Goldrath AW, Hedrick SM. Differentiation of CD8 memory T cells depends on Foxo1. The Journal of Experimental Medicine. 210: 1189-200. PMID 23712431 DOI: 10.1084/Jem.20130392  0.676
2013 Mingueneau M, Kreslavsky T, Gray D, Heng T, Cruse R, Ericson J, Bendall S, Spitzer MH, Nolan GP, Kobayashi K, von Boehmer H, Mathis D, Benoist C, Best AJ, ... ... Goldrath A, et al. The transcriptional landscape of αβ T cell differentiation. Nature Immunology. 14: 619-32. PMID 23644507 DOI: 10.1038/Ni.2590  0.535
2013 Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, et al. Identification of transcriptional regulators in the mouse immune system. Nature Immunology. 14: 633-43. PMID 23624555 DOI: 10.1038/Ni.2587  0.363
2013 Best JA, Blair DA, Knell J, Yang E, Mayya V, Doedens A, Dustin ML, Goldrath AW. Transcriptional insights into the CD8(+) T cell response to infection and memory T cell formation. Nature Immunology. 14: 404-12. PMID 23396170 DOI: 10.1038/Ni.2536  0.665
2013 Knell J, Best JA, Lind NA, Yang E, D'Cruz LM, Goldrath AW. Id2 influences differentiation of killer cell lectin-like receptor G1(hi) short-lived CD8+ effector T cells. Journal of Immunology (Baltimore, Md. : 1950). 190: 1501-9. PMID 23325888 DOI: 10.4049/Jimmunol.1200750  0.647
2012 Li HS, Yang CY, Nallaparaju KC, Zhang H, Liu YJ, Goldrath AW, Watowich SS. The signal transducers STAT5 and STAT3 control expression of Id2 and E2-2 during dendritic cell development. Blood. 120: 4363-73. PMID 23033267 DOI: 10.1182/Blood-2012-07-441311  0.627
2012 Hedrick SM, Hess Michelini R, Doedens AL, Goldrath AW, Stone EL. FOXO transcription factors throughout T cell biology. Nature Reviews. Immunology. 12: 649-61. PMID 22918467 DOI: 10.1038/Nri3278  0.441
2012 Bezman NA, Kim CC, Sun JC, Min-Oo G, Hendricks DW, Kamimura Y, Best JA, Goldrath AW, Lanier LL. Molecular definition of the identity and activation of natural killer cells. Nature Immunology. 13: 1000-9. PMID 22902830 DOI: 10.1038/Ni.2395  0.515
2012 D'Cruz LM, Lind KC, Wu BB, Fujimoto JK, Goldrath AW. Loss of E protein transcription factors E2A and HEB delays memory-precursor formation during the CD8+ T-cell immune response. European Journal of Immunology. 42: 2031-41. PMID 22585759 DOI: 10.1002/Eji.201242497  0.626
2011 Yang CY, Best JA, Knell J, Yang E, Sheridan AD, Jesionek AK, Li HS, Rivera RR, Lind KC, D'Cruz LM, Watowich SS, Murre C, Goldrath AW. The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets. Nature Immunology. 12: 1221-9. PMID 22057289 DOI: 10.1038/Ni.2158  0.753
2011 Monticelli LA, Sonnenberg GF, Abt MC, Alenghat T, Ziegler CG, Doering TA, Angelosanto JM, Laidlaw BJ, Yang CY, Sathaliyawala T, Kubota M, Turner D, Diamond JM, Goldrath AW, Farber DL, et al. Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. Nature Immunology. 12: 1045-54. PMID 21946417 DOI: 10.1031/Ni.2131  0.608
2010 Elpek KG, Rubinstein MP, Bellemare-Pelletier A, Goldrath AW, Turley SJ. Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes. Proceedings of the National Academy of Sciences of the United States of America. 107: 21647-52. PMID 21098276 DOI: 10.1073/Pnas.1012128107  0.476
2010 Doedens AL, Stockmann C, Rubinstein MP, Liao D, Zhang N, DeNardo DG, Coussens LM, Karin M, Goldrath AW, Johnson RS. Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression. Cancer Research. 70: 7465-75. PMID 20841473 DOI: 10.1158/0008-5472.Can-10-1439  0.397
2010 D'Cruz LM, Yang CY, Goldrath AW. Transcriptional regulation of NKT cell development and homeostasis. Current Opinion in Immunology. 22: 199-205. PMID 20171073 DOI: 10.1016/J.Coi.2010.01.014  0.721
2010 D'Cruz LM, Knell J, Fujimoto JK, Goldrath AW. An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells. Nature Immunology. 11: 240-9. PMID 20154672 DOI: 10.1038/Ni.1845  0.551
2010 Elpek KG, Rubinstein MP, Bellemare-Pelletier A, Goldrath AW, Turley SJ. Abstract 3829: Chronic stimulation with IL-15/IL-15Rα complexes leads to NK cell dysfunction Cancer Research. 70: 3829-3829. DOI: 10.1158/1538-7445.Am10-3829  0.464
2009 Monticelli LA, Yang Y, Knell J, D'Cruz LM, Cannarile MA, Engel I, Kronenberg M, Goldrath AW. Transcriptional regulator Id2 controls survival of hepatic NKT cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 19461-6. PMID 19884494 DOI: 10.1073/Pnas.0908249106  0.515
2009 Cheung KP, Yang E, Goldrath AW. Memory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 3364-72. PMID 19675163 DOI: 10.4049/Jimmunol.0900641  0.78
2009 D'Cruz LM, Rubinstein MP, Goldrath AW. Surviving the crash: transitioning from effector to memory CD8+ T cell. Seminars in Immunology. 21: 92-8. PMID 19269192 DOI: 10.1016/J.Smim.2009.02.002  0.652
2008 Rubinstein MP, Lind NA, Purton JF, Filippou P, Best JA, McGhee PA, Surh CD, Goldrath AW. IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response. Blood. 112: 3704-12. PMID 18689546 DOI: 10.1182/Blood-2008-06-160945  0.449
2008 Park KW, Waki H, Villanueva CJ, Monticelli LA, Hong C, Kang S, MacDougald OA, Goldrath AW, Tontonoz P. Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation. Molecular Endocrinology (Baltimore, Md.). 22: 2038-48. PMID 18562627 DOI: 10.1210/Me.2007-0454  0.379
2008 Epardaud M, Elpek KG, Rubinstein MP, Yonekura AR, Bellemare-Pelletier A, Bronson R, Hamerman JA, Goldrath AW, Turley SJ. Interleukin-15/interleukin-15R alpha complexes promote destruction of established tumors by reviving tumor-resident CD8+ T cells. Cancer Research. 68: 2972-83. PMID 18413767 DOI: 10.1158/0008-5472.Can-08-0045  0.396
2007 Rubinstein M, Sprent J, Goldrath A. Augmenting CD8+ T Cell Responses with IL-15/sIL-15Rα Complexes Clinical Immunology. 123. DOI: 10.1016/J.Clim.2007.03.102  0.503
2006 Cannarile MA, Lind NA, Rivera R, Sheridan AD, Camfield KA, Wu BB, Cheung KP, Ding Z, Goldrath AW. Transcriptional regulator Id2 mediates CD8+ T cell immunity. Nature Immunology. 7: 1317-25. PMID 17086188 DOI: 10.1038/Ni1403  0.808
2006 Ikawa T, Kawamoto H, Goldrath AW, Murre C. E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment. The Journal of Experimental Medicine. 203: 1329-42. PMID 16682500 DOI: 10.1084/Jem.20060268  0.459
2006 Luckey CJ, Bhattacharya D, Goldrath AW, Weissman IL, Benoist C, Mathis D. Memory T and memory B cells share a transcriptional program of self-renewal with long-term hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 3304-9. PMID 16492737 DOI: 10.1073/Pnas.0511137103  0.568
2006 Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, ... Goldrath AW, et al. Erratum: Corrigendum: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin Nature Immunology. 7: 113-113. DOI: 10.1038/Ni0106-113  0.482
2005 Intlekofer AM, Takemoto N, Wherry EJ, Longworth SA, Northrup JT, Palanivel VR, Mullen AC, Gasink CR, Kaech SM, Miller JD, Gapin L, Ryan K, Russ AP, Lindsten T, Orange JS, ... Goldrath AW, et al. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nature Immunology. 6: 1236-44. PMID 16273099 DOI: 10.1038/Ni1268  0.655
2005 Goldrath AW, Hedrick SM. Central tolerance matters. Immunity. 23: 113-4. PMID 16111630 DOI: 10.1016/J.Immuni.2005.08.004  0.344
2004 Goldrath AW, Luckey CJ, Park R, Benoist C, Mathis D. The molecular program induced in T cells undergoing homeostatic proliferation. Proceedings of the National Academy of Sciences of the United States of America. 101: 16885-90. PMID 15548615 DOI: 10.1073/Pnas.0407417101  0.6
2002 Goldrath AW, Sivakumar PV, Glaccum M, Kennedy MK, Bevan MJ, Benoist C, Mathis D, Butz EA. Cytokine requirements for acute and Basal homeostatic proliferation of naive and memory CD8+ T cells. The Journal of Experimental Medicine. 195: 1515-22. PMID 12070279 DOI: 10.1084/Jem.20020033  0.591
2002 Goldrath AW. Maintaining the status quo: T-cell homeostasis. Microbes and Infection / Institut Pasteur. 4: 539-45. PMID 11959509 DOI: 10.1016/S1286-4579(02)01570-8  0.54
2000 Goldrath AW, Bogatzki LY, Bevan MJ. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation Journal of Experimental Medicine. 192: 557-564. PMID 10952725 DOI: 10.1084/Jem.192.4.557  0.651
2000 Wong P, Goldrath AW, Rudensky AY. Competition for specific intrathymic ligands limits positive selection in a TCR transgenic model of CD4+ T cell development. Journal of Immunology (Baltimore, Md. : 1950). 164: 6252-9. PMID 10843678 DOI: 10.4049/Jimmunol.164.12.6252  0.42
2000 Bevan MJ, Goldrath AW. T-cell memory: You must remember this.. Current Biology. 10: R338-R340. PMID 10801433 DOI: 10.1016/S0960-9822(00)00461-9  0.57
1999 Goldrath AW, Bevan MJ. Selecting and maintaining a diverse T-cell repertoire Nature. 402: 255-262. PMID 10580495 DOI: 10.1038/46218  0.427
1999 Goldrath AW, Bevan MJ. Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts Immunity. 11: 183-190. PMID 10485653 DOI: 10.1016/S1074-7613(00)80093-X  0.544
1997 Goldrath AW, Hogquist KA, Bevan MJ. CD8 Lineage commitment in the absence of CD8 Immunity. 6: 633-642. PMID 9175841 DOI: 10.1016/S1074-7613(00)80351-9  0.498
1995 Goldrath AW, Barber L, Chen KE, Alters SE. Differences in Adhesion Markers, Activation Markers, and TcR in Islet Infiltratingvs.Peripheral Lymphocytes in the NOD Mouse Journal of Autoimmunity. 8: 209-220. PMID 7612149 DOI: 10.1006/Jaut.1995.0016  0.534
1995 Morkowski S, Goldrath AW, Eastman S, Ramachandra L, Freed DC, Whiteley P, Rudensky AYu. T cell recognition of major histocompatibility complex class II complexes with invariant chain processing intermediates. The Journal of Experimental Medicine. 182: 1403-13. PMID 7595211 DOI: 10.1084/Jem.182.5.1403  0.312
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