Philip E. Auron - Publications

Biological Sciences Duquesne University, Pittsburgh, PA, United States 
Molecular Biology, Cell Biology

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Adamik J, Pulugulla SH, Zhang P, Sun Q, Lontos K, Macar DA, Auron PE, Galson DL. EZH2 supports osteoclast differentiation and bone resorption via epigenetic and cytoplasmic targets. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31487061 DOI: 10.1002/jbmr.3863  0.56
2018 Pulugulla SH, Workman R, Rutter NW, Yang Z, Adamik J, Lupish B, Macar DA, El Abdouni S, Esposito EX, Galson DL, Camacho CJ, Madura JD, Auron PE. A combined computational and experimental approach reveals the structure of a C/EBPβ:Spi-1 interaction required for gene transcription. The Journal of Biological Chemistry. PMID 30355733 DOI: 10.1074/jbc.RA118.005627  0.56
2018 Pulugulla SH, Packard TA, Galloway NLK, Grimmett ZW, Doitsh G, Adamik J, Galson DL, Greene WC, Auron PE. Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes. Cytokine. 111: 373-381. PMID 30300855 DOI: 10.1016/j.cyto.2018.10.001  0.56
2014 Feng H, Lopez GY, Kim CK, Alvarez A, Duncan CG, Nishikawa R, Nagane M, Su AJ, Auron PE, Hedberg ML, Wang L, Raizer JJ, Kessler JA, Parsa AT, Gao WQ, et al. EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. The Journal of Clinical Investigation. 124: 3741-56. PMID 25061874 DOI: 10.1172/JCI73093  0.64
2013 Adamik J, Wang KZ, Unlu S, Su AJ, Tannahill GM, Galson DL, O'Neill LA, Auron PE. Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1β and tumor necrosis factor α. Plos One. 8: e70622. PMID 23936458 DOI: 10.1371/journal.pone.0070622  0.56
2013 Adamik J, Henkel M, Ray A, Auron PE, Duerr R, Barrie A. The IL17A and IL17F loci have divergent histone modifications and are differentially regulated by prostaglandin E2 in Th17 cells. Cytokine. 64: 404-12. PMID 23800789 DOI: 10.1016/j.cyto.2013.05.010  0.64
2013 Tannahill GM, Curtis AM, Adamik J, Palsson-McDermott EM, McGettrick AF, Goel G, Frezza C, Bernard NJ, Kelly B, Foley NH, Zheng L, Gardet A, Tong Z, Jany SS, Corr SC, ... ... Auron PE, et al. Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature. 496: 238-42. PMID 23535595 DOI: 10.1038/nature11986  0.64
2012 Liu A, Gong P, Hyun SW, Wang KZ, Cates EA, Perkins D, Bannerman DD, Puché AC, Toshchakov VY, Fang S, Auron PE, Vogel SN, Goldblum SE. TRAF6 protein couples Toll-like receptor 4 signaling to Src family kinase activation and opening of paracellular pathway in human lung microvascular endothelia. The Journal of Biological Chemistry. 287: 16132-45. PMID 22447928 DOI: 10.1074/jbc.M111.310102  0.64
2011 Tsukada J, Yoshida Y, Kominato Y, Auron PE. The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation. Cytokine. 54: 6-19. PMID 21257317 DOI: 10.1016/j.cyto.2010.12.019  0.68
2010 Wang KZ, Galson DL, Auron PE. TRAF6 is autoinhibited by an intramolecular interaction which is counteracted by trans-ubiquitination. Journal of Cellular Biochemistry. 110: 763-71. PMID 20512936 DOI: 10.1002/jcb.22589  0.56
2008 Listman JA, Race JE, Walker-Kopp N, Unlu S, Auron PE. Inhibition of IL-1beta transcription by peptides derived from the hCMV IE2 transactivator. Molecular Immunology. 45: 2667-77. PMID 18308397 DOI: 10.1016/j.molimm.2007.12.024  0.52
2007 Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR. Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB. Genes & Development. 21: 1396-408. PMID 17510282 DOI: 10.1101/gad.1553707  0.64
2007 Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A, Wolff SM, Dinarello CA. Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc. Natl. Acad. Sci. USA 1984. 81: 7907-7911. Journal of Immunology (Baltimore, Md. : 1950). 178: 5413-7. PMID 17442920  0.64
2007 Unlu S, Kumar A, Waterman WR, Tsukada J, Wang KZQ, Galson DL, Auron PE. Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene Molecular Immunology. 44: 3364-3379. PMID 17386941 DOI: 10.1016/j.molimm.2007.02.016  0.64
2006 Wang KZ, Wara-Aswapati N, Boch JA, Yoshida Y, Hu CD, Galson DL, Auron PE. TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src. Journal of Cell Science. 119: 1579-91. PMID 16569657 DOI: 10.1242/jcs.02889  0.68
2006 Waterman WR, Xu LL, Tetradis S, Motyckova G, Tsukada J, Saito K, Webb AC, Robinson DR, Auron PE. Glucocorticoid inhibits the human pro-interleukin lbeta gene (ILIB) by decreasing DNA binding of transactivators to the signal-responsive enhancer. Molecular Immunology. 43: 773-82. PMID 16095699 DOI: 10.1016/j.molimm.2005.07.003  0.68
2005 Listman JA, Wara-aswapati N, Race JE, Blystone LW, Walker-Kopp N, Yang Z, Auron PE. Conserved ETS domain arginines mediate DNA binding, nuclear localization, and a novel mode of bZIP interaction. The Journal of Biological Chemistry. 280: 41421-8. PMID 16223730 DOI: 10.1074/jbc.M509143200  0.48
2004 Yoshida Y, Kumar A, Koyama Y, Peng H, Arman A, Boch JA, Auron PE. Interleukin 1 Activates STAT3/Nuclear Factor-κB Cross-talk via a Unique TRAF6- and p65-dependent Mechanism Journal of Biological Chemistry. 279: 1768-1776. PMID 14593105 DOI: 10.1074/jbc.M311498200  0.64
2003 Boch JA, Yoshida Y, Koyama Y, Wara-Aswapati N, Peng H, Unlu S, Auron PE. Characterization of a cascade of protein interactions initiated at the IL-1 receptor. Biochemical and Biophysical Research Communications. 303: 525-31. PMID 12659850  0.68
2003 Tan L, Peng H, Osaki M, Choy BK, Auron PE, Sandell LJ, Goldring MB. Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta. The Journal of Biological Chemistry. 278: 17688-700. PMID 12637574 DOI: 10.1074/jbc.M301676200  0.64
2003 Osaki M, Tan L, Choy BK, Yoshida Y, Cheah KS, Auron PE, Goldring MB. The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2. The Biochemical Journal. 369: 103-15. PMID 12223098 DOI: 10.1042/BJ20020928  0.64
2002 Yang Z, Wara-aswapati N, Yoshida Y, Walker N, Galson DL, Listman J, Auron PE. Dual regulatory role of human cytomegalovirus immediate-early protein in IL1B transcription is dependent upon Spi-1/PU.1. Biochemical and Biophysical Research Communications. 294: 854-63. PMID 12061786 DOI: 10.1016/S0006-291X(02)00562-4  0.68
2002 Xie Y, Chen C, Stevenson MA, Hume DA, Auron PE, Calderwood SK. NF-IL6 and HSF1 have mutually antagonistic effects on transcription in monocytic cells. Biochemical and Biophysical Research Communications. 291: 1071-80. PMID 11866474 DOI: 10.1006/bbrc.2002.6562  0.64
2002 Asea A, Rehli M, Kabingu E, Boch JA, Baré O, Auron PE, Stevenson MA, Calderwood SK. Novel signal transduction pathway utilized by extracellular HSP70. Role of toll-like receptor (TLR) 2 and TLR4 Journal of Biological Chemistry. 277: 15028-15034. PMID 11836257 DOI: 10.1074/jbc.M200497200  0.64
2002 Toda Y, Tsukada J, Misago M, Kominato Y, Auron PE, Tanaka Y. Autocrine induction of the human pro-IL-1beta gene promoter by IL-1beta in monocytes. Journal of Immunology (Baltimore, Md. : 1950). 168: 1984-91. PMID 11823535  0.68
2002 Xie Y, Chen C, Stevenson MA, Auron PE, Calderwood SK. Heat shock factor 1 represses transcription of the IL-1beta gene through physical interaction with the nuclear factor of interleukin 6. The Journal of Biological Chemistry. 277: 11802-10. PMID 11801594 DOI: 10.1074/jbc.M109296200  0.64
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