Isa Hussaini - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Cell Biology, Pathology, Oncology

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Merk BC, Owens JL, Lopes MB, Silva CM, Hussaini IM. STAT6 expression in glioblastoma promotes invasive growth. Bmc Cancer. 11: 184. PMID 21595984 DOI: 10.1186/1471-2407-11-184  0.498
2010 Amos S, Redpath GT, Dipierro CG, Carpenter JE, Hussaini IM. Epidermal growth factor receptor-mediated regulation of urokinase plasminogen activator expression and glioblastoma invasion via C-SRC/MAPK/AP-1 signaling pathways. Journal of Neuropathology and Experimental Neurology. 69: 582-92. PMID 20467333 DOI: 10.1097/Nen.0B013E3181E008Fe  0.753
2010 Zhao Y, Xiao A, diPierro CG, Carpenter JE, Abdel-Fattah R, Redpath GT, Lopes MB, Hussaini IM. An extensive invasive intracranial human glioblastoma xenograft model: role of high level matrix metalloproteinase 9. The American Journal of Pathology. 176: 3032-49. PMID 20413683 DOI: 10.2353/Ajpath.2010.090571  0.721
2009 Golding SE, Rosenberg E, Valerie N, Hussaini I, Frigerio M, Cockcroft XF, Chong WY, Hummersone M, Rigoreau L, Menear KA, O'Connor MJ, Povirk LF, van Meter T, Valerie K. Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Molecular Cancer Therapeutics. 8: 2894-902. PMID 19808981 DOI: 10.1158/1535-7163.Mct-09-0519  0.447
2009 Kohutek ZA, diPierro CG, Redpath GT, Hussaini IM. ADAM-10-mediated N-cadherin cleavage is protein kinase C-alpha dependent and promotes glioblastoma cell migration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4605-15. PMID 19357285 DOI: 10.1523/Jneurosci.5126-08.2009  0.694
2008 Zhao Y, Xiao A, Dipierro CG, Abdel-Fattah R, Amos S, Redpath GT, Carpenter JE, Pieper RO, Hussaini IM. H-Ras increases urokinase expression and cell invasion in genetically modified human astrocytes through Ras/Raf/MEK signaling pathway. Glia. 56: 917-24. PMID 18383343 DOI: 10.1002/Glia.20667  0.679
2008 Li Y, Guessous F, Kwon S, Kumar M, Ibidapo O, Fuller L, Johnson E, Lal B, Hussaini I, Bao Y, Laterra J, Schiff D, Abounader R. PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations. Cancer Research. 68: 1723-31. PMID 18339852 DOI: 10.1158/0008-5472.Can-07-1963  0.422
2007 Amos S, Mut M, diPierro CG, Carpenter JE, Xiao A, Kohutek ZA, Redpath GT, Zhao Y, Wang J, Shaffrey ME, Hussaini IM. Protein kinase C-alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion. Cancer Research. 67: 10241-51. PMID 17974965 DOI: 10.1158/0008-5472.Can-07-0030  0.714
2007 Hussaini IM, Trotter C, Zhao Y, Abdel-Fattah R, Amos S, Xiao A, Agi CU, Redpath GT, Fang Z, Leung GK, Lopes MB, Laws ER. Matrix metalloproteinase-9 is differentially expressed in nonfunctioning invasive and noninvasive pituitary adenomas and increases invasion in human pituitary adenoma cell line. The American Journal of Pathology. 170: 356-65. PMID 17200207 DOI: 10.2353/ajpath.2007.060736  0.393
2007 Uht RM, Amos S, Martin PM, Riggan AE, Hussaini IM. The protein kinase C-eta isoform induces proliferation in glioblastoma cell lines through an ERK/Elk-1 pathway. Oncogene. 26: 2885-93. PMID 17146445 DOI: 10.1038/Sj.Onc.1210090  0.405
2007 Martin PM, Aeder SE, Chrestensen CA, Sturgill TW, Hussaini IM. Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta Oncogene. 26: 407-414. PMID 16832347 DOI: 10.1038/Sj.Onc.1209791  0.37
2005 Martin PM, Hussaini IM. PKC eta as a therapeutic target in glioblastoma multiforme. Expert Opinion On Therapeutic Targets. 9: 299-313. PMID 15934917 DOI: 10.1517/14728222.9.2.299  0.327
2005 Amos S, Martin PM, Polar GA, Parsons SJ, Hussaini IM. Phorbol 12-myristate 13-acetate induces epidermal growth factor receptor transactivation via protein kinase Cdelta/c-Src pathways in glioblastoma cells. The Journal of Biological Chemistry. 280: 7729-38. PMID 15618223 DOI: 10.1074/Jbc.M409056200  0.309
2004 Aeder SE, Martin PM, Soh JW, Hussaini IM. PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways. Oncogene. 23: 9062-9. PMID 15489897 DOI: 10.1038/sj.onc.1208093  0.4
2002 Hussaini IM, Carpenter JE, Redpath GT, Sando JJ, Shaffrey ME, Vandenberg SR. Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation. Neuro-Oncology. 4: 9-21. PMID 11772428 DOI: 10.1093/Neuonc/4.1.9  0.35
2000 Hussaini IM, Karns LR, Vinton G, Carpenter JE, Redpath GT, Sando JJ, VandenBerg SR. Phorbol 12-myristate 13-acetate induces protein kinase ceta-specific proliferative response in astrocytic tumor cells. The Journal of Biological Chemistry. 275: 22348-54. PMID 10806212 DOI: 10.1074/Jbc.M003203200  0.371
1999 Hussaini IM, Brown MD, Weaver AM, Carpenter J, Karns LR, Vandenberg SR, Gonias SL. Stable antisense RNA expression neutralizes the activity of low-density lipoprotein receptor-related protein and promotes urokinase accumulation in the medium of an astrocytic tumor cell line. Antisense & Nucleic Acid Drug Development. 9: 183-90. PMID 10355824 DOI: 10.1089/Oli.1.1999.9.183  0.396
1999 Hussaini IM, Brown MD, Karns LR, Carpenter J, Redpath GT, Gonias SL, Vandenberg SR. Epidermal growth factor differentially regulates low density lipoprotein receptor-related protein gene expression in neoplastic and fetal human astrocytes. Glia. 25: 71-84. PMID 9888299 DOI: 10.1002/(Sici)1098-1136(19990101)25:1<71::Aid-Glia7>3.0.Co;2-0  0.418
1998 Mandell JW, Hussaini IM, Zecevic M, Weber MJ, VandenBerg SR. In situ visualization of intratumor growth factor signaling: immunohistochemical localization of activated ERK/MAP kinase in glial neoplasms. The American Journal of Pathology. 153: 1411-23. PMID 9811332 DOI: 10.1016/S0002-9440(10)65728-8  0.425
1998 Nguyen DH, Hussaini IM, Gonias SL. Binding of urokinase-type plasminogen activator to its receptor in MCF-7 cells activates extracellular signal-regulated kinase 1 and 2 which is required for increased cellular motility. The Journal of Biological Chemistry. 273: 8502-7. PMID 9525964 DOI: 10.1074/Jbc.273.14.8502  0.356
1997 Weaver AM, Hussaini IM, Mazar A, Henkin J, Gonias SL. Embryonic fibroblasts that are genetically deficient in low density lipoprotein receptor-related protein demonstrate increased activity of the urokinase receptor system and accelerated migration on vitronectin Journal of Biological Chemistry. 272: 14372-14379. PMID 9162074 DOI: 10.1074/Jbc.272.22.14372  0.318
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