Linzhao Cheng - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology, Molecular Biology

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Deng J, Lancelot M, Jajosky R, Deng Q, Deeb K, Saakadze N, Gao Y, Jaye D, Liu S, Stowell SR, Cheng L, Roback JD. Erythropoietic Properties of Human iPSC-derived RBCs in Immunodeficient Mice. American Journal of Hematology. PMID 34779029 DOI: 10.1002/ajh.26410  0.386
2021 Kammers K, Taub MA, Mathias RA, Yanek LR, Kanchan K, Venkatraman V, Sundararaman N, Martin J, Liu S, Hoyle D, Raedschelders K, Holewinski R, Parker S, Dardov V, Faraday N, ... ... Cheng L, et al. Gene and protein expression in human megakaryocytes derived from induced pluripotent stem cells. Journal of Thrombosis and Haemostasis : Jth. PMID 33829634 DOI: 10.1111/jth.15334  0.49
2021 Liu S, Wu M, Lancelot M, Deng J, Gao Y, Roback JD, Chen T, Cheng L. BMI1 enables extensive expansion of functional erythroblasts from human peripheral blood mononuclear cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 33484967 DOI: 10.1016/j.ymthe.2021.01.022  0.398
2020 Das D, Li J, Liu S, Oh E, Cheng L, Lyketsos C, Mahairaki V. Generation and characterization of a novel human iPSC line from a resilient Alzheimer's disease patient. Stem Cell Research. 48: 101979. PMID 32916633 DOI: 10.1016/J.Scr.2020.101979  0.482
2020 Das D, Li J, Cheng L, Franco S, Mahairaki V. Human Forebrain Organoids from Induced Pluripotent Stem Cells: A Novel Approach to Model Repair of Ionizing Radiation-Induced DNA Damage in Human Neurons. Radiation Research. 194: 191-198. PMID 32845994 DOI: 10.1667/Rr15567.1  0.425
2020 Morales Pantoja IE, Smith MD, Rajbhandari L, Cheng L, Gao Y, Mahairaki V, Venkatesan A, Calabresi PA, Fitzgerald KC, Whartenby KA. iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu. Plos One. 15: e0233980. PMID 32511247 DOI: 10.1371/Journal.Pone.0233980  0.44
2020 Kanchan K, Iyer K, Yanek LR, Carcamo-Orive I, Taub MA, Malley C, Baldwin K, Becker LC, Broeckel U, Cheng L, Cowan C, D'Antonio M, Frazer KA, Quertermous T, Mostoslavsky G, et al. Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program. Stem Cell Research. 46: 101803. PMID 32442913 DOI: 10.1016/J.Scr.2020.101803  0.441
2020 Choi IY, Lim H, Cho HJ, Oh Y, Chou BK, Bai H, Cheng L, Kim YJ, Hyun S, Kim H, Shin JH, Lee G. Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors. Elife. 9. PMID 32011235 DOI: 10.7554/Elife.46981  0.509
2019 Katt ME, Mayo LN, Ellis SE, Mahairaki V, Rothstein JD, Cheng L, Searson PC. The role of mutations associated with familial neurodegenerative disorders on blood-brain barrier function in an iPSC model. Fluids and Barriers of the Cns. 16: 20. PMID 31303172 DOI: 10.1186/S12987-019-0139-4  0.363
2019 Shen J, Zhu Y, Lyu C, Feng Z, Lyu S, Zhao Y, Hoyle DL, Ji G, Miao W, Zhang X, Cheng L, Brodsky RA, Cheng T, Wang ZZ. Sequential cellular niches control the generation of enucleated erythrocytes from human pluripotent stem cells. Haematologica. PMID 31197070 DOI: 10.3324/Haematol.2018.211664  0.542
2019 Liu S, Mahairaki V, Bai H, Ding Z, Li J, Witwer KW, Cheng L. Highly purified human extracellular vesicles produced by stem cells alleviate aging cellular phenotypes of senescent human cells. Stem Cells (Dayton, Ohio). PMID 30811771 DOI: 10.1002/Stem.2996  0.551
2019 Wu M, Liu S, Cheng L, Chen T. Elucidating an Essential Role of Promoting Endothelial-to-Hematopoietic Transition By a Key EMT-Regulator ZEB2 Using a Human iPSC-Based Model Blood. 134: 3716-3716. DOI: 10.1182/Blood-2019-126908  0.344
2018 Linville RM, DeStefano JG, Sklar MB, Xu Z, Farrell AM, Bogorad MI, Chu C, Walczak P, Cheng L, Mahairaki V, Whartenby KA, Calabresi PA, Searson PC. Human iPSC-derived blood-brain barrier microvessels: validation of barrier function and endothelial cell behavior. Biomaterials. 190: 24-37. PMID 30391800 DOI: 10.1016/J.Biomaterials.2018.10.023  0.345
2018 Li C, Cheng L, Wu H, He P, Zhang Y, Yang Y, Chen J, Chen M. Activation of the KEAP1‑NRF2‑ARE signaling pathway reduces oxidative stress in Hep2 cells. Molecular Medicine Reports. PMID 30015918 DOI: 10.3892/mmr.2018.9288  0.376
2018 Wei S, Wang J, Oyinlade O, Ma D, Wang S, Kratz L, Lal B, Xu Q, Liu S, Shah SR, Zhang H, Li Y, Quiñones-Hinojosa A, Zhu H, Huang ZY, ... Cheng L, et al. Heterozygous IDH1 created by "single base editing" inhibits human astroglial cell growth by downregulating YAP. Oncogene. PMID 29849122 DOI: 10.1038/S41388-018-0334-9  0.363
2018 Wu M, Liu S, Gao Y, Bai H, Machairaki V, Li G, Chen T, Cheng L. Conditional gene knockout and reconstitution in human iPSCs with an inducible Cas9 system. Stem Cell Research. 29: 6-14. PMID 29554589 DOI: 10.1016/J.Scr.2018.03.003  0.493
2018 Alkadi H, McKellar D, Zhen T, Karpova T, Garrett LJ, Gao Y, Alsadhan AA, Kwon EM, Greene JJ, Ball DA, Cheng L, Sorrell AD, Liu PP. The VWRPY Domain Is Essential for RUNX1 Function in Hematopoietic Progenitor Cell Maturation and Megakaryocyte Differentiation Blood. 132: 1319-1319. DOI: 10.1182/Blood-2018-99-113400  0.451
2017 Cai L, Bai H, Mahairaki V, Gao Y, He C, Wen Y, Jin YC, Wang Y, Pan RL, Qasba A, Ye Z, Cheng L. A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. Stem Cells Translational Medicine. PMID 29164808 DOI: 10.1002/Sctm.17-0066  0.714
2017 Li Y, Jin C, Bai H, Gao Y, Sun S, Chen L, Qin L, Liu PP, Cheng L, Wang QF. Human NOTCH4 is a key target of RUNX1 in megakaryocytic differentiation. Blood. PMID 29101237 DOI: 10.1182/Blood-2017-04-780379  0.536
2017 Yuan X, Li Z, Baines AC, Gavriilaki E, Ye Z, Wen Z, Braunstein EM, Biesecker LG, Cheng L, Dong X, Brodsky RA. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. Plos One. 12: e0174074. PMID 28441409 DOI: 10.1371/Journal.Pone.0174074  0.689
2017 Liu S, Ye Z, Gao Y, He C, Williams DW, Moliterno A, Spivak J, Huang H, Cheng L. Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene. Stem Cell Research. 18: 57-59. PMID 28395806 DOI: 10.1016/J.Scr.2016.12.012  0.745
2017 Yang C, Shang X, Cheng L, Yang L, Liu X, Bai C, Wei Z, Hua J, Li G. DNMT 1 maintains hypermethylation of CAG promoter specific region and prevents expression of exogenous gene in fat-1 transgenic sheep. Plos One. 12: e0171442. PMID 28158319 DOI: 10.1371/journal.pone.0171442  0.306
2017 Kammers K, Taub MA, Ruczinski I, Martin J, Yanek LR, Frazee A, Gao Y, Hoyle D, Faraday N, Becker DM, Cheng L, Wang ZZ, Leek JT, Becker LC, Mathias RA. Integrity of Induced Pluripotent Stem Cell (iPSC) Derived Megakaryocytes as Assessed by Genetic and Transcriptomic Analysis. Plos One. 12: e0167794. PMID 28107356 DOI: 10.1371/Journal.Pone.0167794  0.482
2016 Bhatt N, Ghosh R, Roy S, Gao Y, Armanios M, Cheng L, Franco S. Integration-free erythroblast-derived human induced pluripotent stem cells (iPSCs) from an individual with Ataxia-Telangiectasia (A-T). Stem Cell Research. 17: 205-207. PMID 27879207 DOI: 10.1016/J.Scr.2016.08.003  0.56
2016 Bhatt N, Ghosh R, Roy S, Gao Y, Armanios M, Cheng L, Franco S. Robust reprogramming of Ataxia-Telangiectasia patient and carrier erythroid cells to induced pluripotent stem cells. Stem Cell Research. 17: 296-305. PMID 27596957 DOI: 10.1016/J.Scr.2016.08.006  0.568
2016 Long H, Miller SF, Strauss C, Zhao C, Cheng L, Ye Z, Griffin K, Te R, Lee H, Chen CC, Lynch M. Antibiotic treatment enhances the genome-wide mutation rate of target cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091991 DOI: 10.1073/Pnas.1601208113  0.602
2016 Smith C, Ye Z, Cheng L. Genome Editing in Human Pluripotent Stem Cells. Cold Spring Harbor Protocols. 2016: pdb.top086819. PMID 27037079 DOI: 10.1101/Pdb.Top086819  0.735
2016 Smith C, Ye Z, Cheng L. A Method for Genome Editing in Human Pluripotent Stem Cells. Cold Spring Harbor Protocols. 2016: pdb.prot090217. PMID 27037073 DOI: 10.1101/Pdb.Prot090217  0.712
2016 Senquan L, Williams DM, Moliterno AR, Spivak JL, Huang H, Gao Y, Ye Z, Cheng L. Generation, Characterization and Genetic Modification of Human iPSCs Containing Calr, MPL and JAK2 Mutations Found in MPN Patients Blood. 128: 3139-3139. DOI: 10.1182/Blood.V128.22.3139.3139  0.735
2016 Alkadi HI, Karpova TS, Kwon EM, Garrett LJ, Gao Y, Wincovitch S, Alsadhan A, Greene JJ, Ball DA, Cheng L, Sorrell AD, Liu PP. Unraveling a Novel Mechanism of RUNX1 Activity in Familial Platelet Disorder with Associated Myeloid Malignancy Blood. 128: 2693-2693. DOI: 10.1182/Blood.V128.22.2693.2693  0.412
2015 Bai H, Liu Y, Xie Y, Hoyle DL, Brodsky RA, Cheng L, Cheng T, Wang ZZ. Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated from Hemogenic Endothelial Cells in Human Pluripotent Stem Cells. Journal of Cellular Physiology. PMID 26395760 DOI: 10.1002/Jcp.25199  0.534
2015 Chou BK, Gu H, Gao Y, Dowey SN, Wang Y, Shi J, Li Y, Ye Z, Cheng T, Cheng L. A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach. Stem Cells Translational Medicine. 4: 320-32. PMID 25742692 DOI: 10.5966/Sctm.2014-0214  0.775
2015 Liu Y, Wang Y, Gao Y, Forbes JA, Qayyum R, Becker L, Cheng L, Wang ZZ. Efficient generation of megakaryocytes from human induced pluripotent stem cells using food and drug administration-approved pharmacological reagents. Stem Cells Translational Medicine. 4: 309-19. PMID 25713465 DOI: 10.5966/Sctm.2014-0183  0.533
2015 Wang J, Wang N, Jin Y, Si J, Tan ZK, Du H, Cheng L, Dai X, Bai S, He H, Ye Z, Lai ML, Friend RH, Huang W. Interfacial control toward efficient and low-voltage perovskite light-emitting diodes. Advanced Materials (Deerfield Beach, Fla.). 27: 2311-6. PMID 25708283 DOI: 10.1002/Adma.201405217  0.533
2015 Huang X, Wang Y, Yan W, Smith C, Ye Z, Wang J, Gao Y, Mendelsohn L, Cheng L. Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation. Stem Cells (Dayton, Ohio). 33: 1470-9. PMID 25702619 DOI: 10.1002/Stem.1969  0.769
2015 All AH, Gharibani P, Gupta S, Bazley FA, Pashai N, Chou BK, Shah S, Resar LM, Cheng L, Gearhart JD, Kerr CL. Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. Plos One. 10: e0116933. PMID 25635918 DOI: 10.1371/Journal.Pone.0116933  0.493
2015 Smith C, Abalde-Atristain L, He C, Brodsky BR, Braunstein EM, Chaudhari P, Jang YY, Cheng L, Ye Z. Efficient and allele-specific genome editing of disease loci in human iPSCs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 570-7. PMID 25418680 DOI: 10.1038/Mt.2014.226  0.701
2015 All AH, Gharibani P, Gupta S, Bazley FA, Pashai N, Chou B, Shah S, Resar LM, Cheng L, Gearhart JD, Kerr CL. Bright field microscopy images of the various stages of oligodendrocyte differentiation from induced pluripotent stem cells of the BC1 line. Plos One. DOI: 10.1371/Journal.Pone.0116933.G001  0.45
2015 Braunstein EM, Li R, Sobreira N, Gocke C, Brodsky RA, Valle D, Cheng L. A Germline Mutation in ERBB3 Predisposes to Inherited Erythroid Myelodysplasia/Erythroleukemia Blood. 126: 4105-4105. DOI: 10.1182/Blood.V126.23.4105.4105  0.385
2015 Chou B, Bai H, Gao Y, Wang Y, Ye Z, Kwon EM, Liu PP, Friedman AD, Wang ZZ, Cheng L. The Roles of RUNX1 in Human Hematopoiesis and Megakaryopoiesis Revealed By Genome-Targeted Human iPSCs and an Improved Hematopoietic Differentiation Model Blood. 126: 1167-1167. DOI: 10.1182/Blood.V126.23.1167.1167  0.765
2014 Cai J, Miao X, Li Y, Smith C, Tsang K, Cheng L, Wang QF. Whole-genome sequencing identifies genetic variances in culture-expanded human mesenchymal stem cells. Stem Cell Reports. 3: 227-33. PMID 25254336 DOI: 10.1016/J.Stemcr.2014.05.019  0.433
2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, ... ... Cheng L, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515: 414-8. PMID 25132547 DOI: 10.1038/Nature13716  0.352
2014 Connelly JP, Kwon EM, Gao Y, Trivedi NS, Elkahloun AG, Horwitz MS, Cheng L, Liu PP. Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects. Blood. 124: 1926-30. PMID 25114263 DOI: 10.1182/Blood-2014-01-550525  0.462
2014 Smith C, Gore A, Yan W, Abalde-Atristain L, Li Z, He C, Wang Y, Brodsky RA, Zhang K, Cheng L, Ye Z. Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs. Cell Stem Cell. 15: 12-3. PMID 24996165 DOI: 10.1016/J.Stem.2014.06.011  0.696
2014 Huang K, Shen Y, Xue Z, Bibikova M, April C, Liu Z, Cheng L, Nagy A, Pellegrini M, Fan JB, Fan G. A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports. 2: 36-43. PMID 24511466 DOI: 10.1016/J.Stemcr.2013.11.003  0.442
2014 Shah S, Huang X, Cheng L. Concise review: stem cell-based approaches to red blood cell production for transfusion. Stem Cells Translational Medicine. 3: 346-55. PMID 24361925 DOI: 10.5966/Sctm.2013-0054  0.415
2014 Belet S, Fieremans N, Yuan X, Van Esch H, Verbeeck J, Ye Z, Cheng L, Brodsky BR, Hu H, Kalscheuer VM, Brodsky RA, Froyen G. Early frameshift mutation in PIGA identified in a large XLID family without neonatal lethality. Human Mutation. 35: 350-5. PMID 24357517 DOI: 10.1002/Humu.22498  0.644
2014 Tang M, Chen W, Liu J, Weir MD, Cheng L, Xu HH. Human induced pluripotent stem cell-derived mesenchymal stem cell seeding on calcium phosphate scaffold for bone regeneration. Tissue Engineering. Part A. 20: 1295-305. PMID 24279868 DOI: 10.1089/ten.TEA.2013.0211  0.401
2014 Wang Y, Cheng L, Gerecht S. Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013. Annals of Biomedical Engineering. 42: 1357-72. PMID 24132657 DOI: 10.1007/S10439-013-0921-4  0.438
2014 Ye Z, Liu CF, Lanikova L, Dowey SN, He C, Huang X, Brodsky RA, Spivak JL, Prchal JT, Cheng L. Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 32: 269-78. PMID 24105986 DOI: 10.1002/Stem.1545  0.726
2014 Huang X, Shah S, Wang J, Ye Z, Dowey SN, Tsang KM, Mendelsohn LG, Kato GJ, Kickler TS, Cheng L. Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 451-63. PMID 24002691 DOI: 10.1038/Mt.2013.201  0.742
2014 Yu Y, Liang D, Tian Q, Chen X, Jiang B, Chou BK, Hu P, Cheng L, Gao P, Li J, Wang G. Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis. Stem Cells (Dayton, Ohio). 32: 349-63. PMID 23765875 DOI: 10.1002/Stem.1447  0.463
2013 TheinHan W, Liu J, Tang M, Chen W, Cheng L, Xu HH. Induced pluripotent stem cell-derived mesenchymal stem cell seeding on biofunctionalized calcium phosphate cements. Bone Research. 4: 371-384. PMID 24839581 DOI: 10.4248/BR201304008  0.424
2013 Yuan X, Braunstein EM, Ye Z, Liu CF, Chen G, Zou J, Cheng L, Brodsky RA. Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 819-29. PMID 24113066 DOI: 10.5966/Sctm.2013-0069  0.789
2013 Chou BK, Cheng L. And then there were none: no need for pluripotency factors to induce reprogramming. Cell Stem Cell. 13: 261-2. PMID 24012365 DOI: 10.1016/J.Stem.2013.08.004  0.385
2013 Wang Y, Chou BK, Dowey S, He C, Gerecht S, Cheng L. Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. Stem Cell Research. 11: 1103-16. PMID 23973800 DOI: 10.1016/J.Scr.2013.07.011  0.488
2013 Yan W, Smith C, Cheng L. Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing. Scientific Reports. 3: 2376. PMID 23921522 DOI: 10.1038/Srep02376  0.371
2013 Kusuma S, Shen YI, Hanjaya-Putra D, Mali P, Cheng L, Gerecht S. Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix. Proceedings of the National Academy of Sciences of the United States of America. 110: 12601-6. PMID 23858432 DOI: 10.1073/pnas.1306562110  0.664
2013 Ran D, Lam K, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells. Blood. 121: 5252-3. PMID 23813938 DOI: 10.1182/Blood-2013-04-494914  0.759
2013 Chou BK, Ye Z, Cheng L. Generation and homing of iPSC-derived hematopoietic cells in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1292-3. PMID 23812546 DOI: 10.1038/Mt.2013.129  0.767
2013 Ran D, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood. 121: 2882-90. PMID 23372166 DOI: 10.1182/Blood-2012-08-451641  0.774
2013 Kwon EM, Connelly JP, Gao Y, Horwitz M, Cheng L, Liu PP. Targeted correction Of RUNX1 Mutation In The FPD Patient-Specific Induced Pluripotent Stem Cells Restores Megakaryocytic Differentiation Blood. 122: 738-738. DOI: 10.1182/Blood.V122.21.738.738  0.506
2013 Liu Y, Gao Y, Shah S, Becker L, Cheng L, Wang ZZ. FDA-Approved Pharmacological Agents, Romiplostium and Oprelvekin, Synergistically Promote Megakaryocytic Differentiation From Human iPSCs In a Chemically Defined System Blood. 122: 1208-1208. DOI: 10.1182/Blood.V122.21.1208.1208  0.5
2012 Wei KL, Yang YJ, Yao YJ, Du LZ, Wang QH, Wang RH, Wang L, Lin Y, Liu J, Wang H, Wang XL, Wu HM, Wu K, Chen Y, Zhong XY, ... ... Cheng LX, et al. Epidemiologic survey on hospitalized neonates in China. Translational Pediatrics. 1: 15-22. PMID 26835259 DOI: 10.3978/j.issn.2224-4336.2011.10.01  0.525
2012 Dowey SN, Huang X, Chou BK, Ye Z, Cheng L. Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nature Protocols. 7: 2013-21. PMID 23080273 DOI: 10.1038/Nprot.2012.121  0.761
2012 Ye Z, Chou BK, Cheng L. Promise and challenges of human iPSC-based hematologic disease modeling and treatment. International Journal of Hematology. 95: 601-9. PMID 22619021 DOI: 10.1007/S12185-012-1095-9  0.733
2012 Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JS, Gerecht S, Wirtz D. The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. Plos One. 7: e36689. PMID 22574215 DOI: 10.1371/Journal.Pone.0036689  0.702
2012 Cheng L, Hansen NF, Zhao L, Du Y, Zou C, Donovan FX, Chou BK, Zhou G, Li S, Dowey SN, Ye Z, Chandrasekharappa SC, Yang H, Mullikin JC, et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell. 10: 337-44. PMID 22385660 DOI: 10.1016/J.Stem.2012.01.005  0.72
2012 Johnston JJ, Gropman AL, Sapp JC, Teer JK, Martin JM, Liu CF, Yuan X, Ye Z, Cheng L, Brodsky RA, Biesecker LG. The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria. American Journal of Human Genetics. 90: 295-300. PMID 22305531 DOI: 10.1016/J.Ajhg.2011.11.031  0.65
2012 Zou C, Chou BK, Dowey SN, Tsang K, Huang X, Liu CF, Smith C, Yen J, Mali P, Zhang YA, Cheng L, Ye Z. Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Stem Cells and Development. 21: 2298-311. PMID 22225458 DOI: 10.1089/Scd.2011.0688  0.837
2012 Mali P, Cheng L. Concise review: Human cell engineering: cellular reprogramming and genome editing. Stem Cells (Dayton, Ohio). 30: 75-81. PMID 21905170 DOI: 10.1002/Stem.735  0.749
2012 Huang X, Shah S, Wang Y, Dowey SN, Ye Z, Cheng L. Extensive Ex Vivo Expansion of Functional Human Erythroid Precursor Cells From Reprogrammed Post-Natal Blood Mononuclear Cells by Defined Factors Blood. 120: 975-975. DOI: 10.1182/Blood.V120.21.975.975  0.744
2012 Yuan X, Ye Z, Liu CF, Zou J, Cheng L, Brodsky RA. Generation of GPI Anchor Deficient Blood Cells From Human iPSCs. Blood. 120: 2358-2358. DOI: 10.1182/Blood.V120.21.2358.2358  0.777
2012 Tian L, Piterkova L, Wang L, Ye Z, Cheng L, Wheeler DA, Hakonarson H, Prchal JT. Whole Genome Sequencing of Four CD34+-Derived iPSC Polycythemia Vera Clones From a Single Female Blood. 120: 1755-1755. DOI: 10.1182/Blood.V120.21.1755.1755  0.693
2012 Chen S, Brennen N, Brodsky RA, Cheng L, Denmeade SR, Isaacs JT. Abstract 5699: Mesenchymal stem cells (MSCs) as a selective delivery vehicle for a PSA-activated protoxin for advanced prostate cancer Cancer Research. 72: 5699-5699. DOI: 10.1158/1538-7445.Am2012-5699  0.422
2011 Cheng L, Blazar B, High K, Porteus M. Zinc fingers hit off target. Nature Medicine. 17: 1192-3. PMID 21988995 DOI: 10.1038/Nm1011-1192  0.312
2011 Zou J, Mali P, Huang X, Dowey SN, Cheng L. Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood. 118: 4599-608. PMID 21881051 DOI: 10.1182/Blood-2011-02-335554  0.701
2011 Choi SM, Liu H, Chaudhari P, Kim Y, Cheng L, Feng J, Sharkis S, Ye Z, Jang YY. Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent Stem cells Blood. 118: 1801-1805. PMID 21628406 DOI: 10.1182/Blood-2011-03-340620  0.744
2011 Jang YY, Ye Z, Cheng L. Molecular imaging and stem cell research. Molecular Imaging. 10: 111-22. PMID 21439256 DOI: 10.2310/7290.2010.00046  0.743
2011 Zou J, Sweeney CL, Chou BK, Choi U, Pan J, Wang H, Dowey SN, Cheng L, Malech HL. Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting. Blood. 117: 5561-72. PMID 21411759 DOI: 10.1182/Blood-2010-12-328161  0.388
2011 Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, Mallett C, Ye Z, Witting S, Cornetta K, Cheng L, Yoder MC. Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood. 117: 4773-7. PMID 21393480 DOI: 10.1182/Blood-2011-01-330514  0.757
2011 Wang B, Zhang YB, Zhang F, Lin H, Wang X, Wan N, Ye Z, Weng H, Zhang L, Li X, Yan J, Wang P, Wu T, Cheng L, Wang J, et al. On the origin of Tibetans and their genetic basis in adapting high-altitude environments. Plos One. 6: e17002. PMID 21386899 DOI: 10.1371/Journal.Pone.0017002  0.571
2011 Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Research. 21: 518-29. PMID 21243013 DOI: 10.1038/Cr.2011.12  0.833
2011 Ye Z, Piterkova L, Liu CF, Dowey SN, Chou B, Huang X, Spivak JL, Swierczek S, Moliterno AR, Prchal JT, Cheng L. Distinct Induced Pluripotent Stem Cell Clones with Somatic Mutations Prepared From PV Patients Blood. 118: 2826-2826. DOI: 10.1182/Blood.V118.21.2826.2826  0.759
2010 Li D, Zhou J, Wang L, Shin ME, Su P, Lei X, Kuang H, Guo W, Yang H, Cheng L, Tanaka TS, Leckband DE, Reynolds AB, Duan E, Wang F. Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. The Journal of Cell Biology. 191: 631-44. PMID 20974810 DOI: 10.1083/Jcb.201006094  0.349
2010 Ohm JE, Mali P, Van Neste L, Berman DM, Liang L, Pandiyan K, Briggs KJ, Zhang W, Argani P, Simons B, Yu W, Matsui W, Van Criekinge W, Rassool FV, Zambidis E, ... ... Cheng L, et al. Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Research. 70: 7662-73. PMID 20841480 DOI: 10.1158/0008-5472.Can-10-1361  0.745
2010 Swistowski A, Peng J, Liu Q, Mali P, Rao MS, Cheng L, Zeng X. Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (Dayton, Ohio). 28: 1893-904. PMID 20715183 DOI: 10.1002/Stem.499  0.729
2010 Ye Z, Cheng L. Potential of human induced pluripotent stem cells derived from blood and other postnatal cell types. Regenerative Medicine. 5: 521-30. PMID 20632856 DOI: 10.2217/Rme.10.38  0.784
2010 Kerr CL, Cheng L. Multiple, interconvertible states of human pluripotent stem cells. Cell Stem Cell. 6: 497-9. PMID 20569683 DOI: 10.1016/J.Stem.2010.05.014  0.568
2010 Mali P, Ye Z, Chou BK, Yen J, Cheng L. An improved method for generating and identifying human induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 636: 191-205. PMID 20336524 DOI: 10.1007/978-1-60761-691-7_12  0.828
2010 Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, Baylin SB, Yusa K, Bradley A, Meyers DJ, Mukherjee C, Cole PA, ... Cheng L, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (Dayton, Ohio). 28: 713-20. PMID 20201064 DOI: 10.1002/Stem.402  0.833
2010 Zou J, Cochran R, Cheng L. Double knockouts in human embryonic stem cells. Cell Research. 20: 250-2. PMID 20190774 DOI: 10.1038/Cr.2010.29  0.567
2010 Kerr CL, Cheng L. The dazzle in germ cell differentiation. Journal of Molecular Cell Biology. 2: 26-9. PMID 20008336 DOI: 10.1093/Jmcb/Mjp041  0.565
2010 Huang X, Chou B, Mali P, Ye Z, Dowey SN, Cheng L. Human IPS Cells Generated From Adult Peripheral Blood Cells and Purified CD34+ Cells by a Non-Integrating Plasmid. Blood. 116: 1589-1589. DOI: 10.1182/Blood.V116.21.1589.1589  0.834
2010 Kerr CL, Cheng L. Multiple, interconvertible states of human pluripotent stem cells (Cell Stem Cell (2010) 6 (497-499)) Cell Stem Cell. 7. DOI: 10.1016/J.Stem.2010.07.009  0.573
2009 Ye Z, Zhan H, Mali P, Dowey S, Williams DM, Jang YY, Dang CV, Spivak JL, Moliterno AR, Cheng L. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Blood. 114: 5473-5480. PMID 19797525 DOI: 10.1182/Blood-2009-04-217406  0.846
2009 Cheng L. Better positioned in stem cells. Blood. 114: 1285-6. PMID 19679697 DOI: 10.1182/Blood-2009-05-221754  0.599
2009 Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 5: 97-110. PMID 19540188 DOI: 10.1016/J.Stem.2009.05.023  0.82
2009 Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L. Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Research. 19: 370-9. PMID 19114988 DOI: 10.1038/Cr.2008.329  0.711
2009 Wei XD, Zhou L, Cheng L, Tian J, Jiang JJ, Maccallum J. In vivo investigation of CD133 as a putative marker of cancer stem cells in Hep-2 cell line. Head & Neck. 31: 94-101. PMID 18853445 DOI: 10.1002/Hed.20935  0.413
2009 Durai M, Krueger C, Ye Z, Cheng L, Mackensen A, Oelke M, Schneck JP. In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC). Cancer Immunology, Immunotherapy : Cii. 58: 209-20. PMID 18563409 DOI: 10.1007/S00262-008-0542-1  0.657
2009 Ye Z, Zhan H, Mali P, Dowey S, Williams D, Jang Y, Van Dang C, Spivak JL, Moliterno AR, Cheng L. Hematopoiesis of Human Induced Pluripotent Stem Cells Derived From Blood Cells of Healthy Donors and Patients with the JAK2-V617F Somatic Mutation. Blood. 114: 812-812. DOI: 10.1182/Blood.V114.22.812.812  0.847
2008 Hwang NS, Varghese S, Lee HJ, Zhang Z, Ye Z, Bae J, Cheng L, Elisseeff J. In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 20641-6. PMID 19095799 DOI: 10.1073/Pnas.0809680106  0.747
2008 Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Jove R, Aplan P, Lin YW, Wertzler K, Reeves R, et al. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research. 68: 10121-7. PMID 19074878 DOI: 10.1158/0008-5472.Can-08-2121  0.692
2008 Wu Z, Zhang W, Chen G, Cheng L, Liao J, Jia N, Gao Y, Dai H, Yuan J, Cheng L, Xiao L. Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells. The Journal of Biological Chemistry. 283: 24991-5002. PMID 18596037 DOI: 10.1074/Jbc.M803893200  0.503
2008 Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L. Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells (Dayton, Ohio). 26: 1998-2005. PMID 18511599 DOI: 10.1634/Stemcells.2008-0346  0.84
2008 Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L. Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell. 2: 461-71. PMID 18462696 DOI: 10.1016/J.Stem.2008.03.001  0.805
2008 Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L. Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins. Cell Stem Cell. 2: 345-55. PMID 18397754 DOI: 10.1016/J.Stem.2008.02.004  0.823
2008 Cheng L, Xiao L, Zeng F, Zhang YA. Stem cells shine in Shanghai. Cell Stem Cell. 2: 34-7. PMID 18371419 DOI: 10.1016/J.Stem.2007.12.010  0.377
2008 Ye Z, Yu X, Cheng L. Lentiviral gene transduction of mouse and human stem cells. Methods in Molecular Biology (Clifton, N.J.). 430: 243-53. PMID 18370304 DOI: 10.1007/978-1-59745-182-6_17  0.778
2008 Cheng L. More new lines of human parthenogenetic embryonic stem cells Cell Research. 18: 215-217. PMID 18246085 DOI: 10.1038/Cr.2008.19  0.533
2008 Resar L, Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Lin Y, Aplan PD, Jove R, Kowalski J, et al. The HMGA1a-STAT3 axis: an “Achilles Heel” for Hematopoietic Malignancies Overexpressing HMGA1a? Blood. 112: 3810-3810. DOI: 10.1182/Blood.V112.11.3810.3810  0.715
2008 Ye Z, Yu X, Cheng L. Efficient Production of Human Hematopoietic Progenitors from Human Pluripotent Stem Cells Using Chemically Defined Media without Serum or Feeder Cells Blood. 112: 2463-2463. DOI: 10.1182/Blood.V112.11.2463.2463  0.774
2008 Savage WJ, Barber J, Cheng L, Chen G, Thoburn C, Hu R, Mukhina G, Matsui W, Hess A, Jones R, Brodsky RA. GPI-Anchored Protein Deficiency Confers Resistance to Apoptosis in PNH. Blood. 112: 2035-2035. DOI: 10.1182/Blood.V112.11.2035.2035  0.43
2008 Cheng L. Human embryonic stem cells as a research model for human biology and diseases Cell Research. 18. DOI: 10.1038/Cr.2008.98  0.617
2007 Baba S, Cho SY, Ye Z, Cheng L, Engles JM, Wahl RL. How reproducible is bioluminescent imaging of tumor cell growth? Single time point versus the dynamic measurement approach. Molecular Imaging. 6: 315-22. PMID 18092516 DOI: 10.2310/7290.2007.00031  0.605
2007 Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, Bhujwalla ZM, Felsher DW, Cheng L, Pevsner J, Lee LA, Semenza GL, Dang CV. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell. 12: 230-8. PMID 17785204 DOI: 10.1016/J.Ccr.2007.08.004  0.304
2007 Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D. FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells. British Journal of Haematology. 137: 64-75. PMID 17359372 DOI: 10.1111/J.1365-2141.2007.06525.X  0.777
2007 Zhou L, Wei X, Cheng L, Tian J, Jiang JJ. CD133, one of the markers of cancer stem cells in Hep-2 cell line. The Laryngoscope. 117: 455-60. PMID 17334305 DOI: 10.1097/01.Mlg.0000251586.15299.35  0.43
2007 Cai L, Ye Z, Zhou BY, Mali P, Zhou C, Cheng L. Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Research. 17: 62-72. PMID 17211448 DOI: 10.1038/Sj.Cr.7310138  0.838
2007 Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nature Genetics. 39: 237-42. PMID 17211412 DOI: 10.1038/Ng1972  0.483
2007 Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L. Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells (Dayton, Ohio). 25: 779-89. PMID 17158240 DOI: 10.1634/Stemcells.2006-0128  0.75
2006 Dravid G, Hammond H, Cheng L. Culture of human embryonic stem cells on human and mouse feeder cells. Methods in Molecular Biology (Clifton, N.J.). 331: 91-104. PMID 16881511 DOI: 10.1385/1-59745-046-4:91  0.587
2006 Cheng L, Qiu RZ, Deng H, Zhang YA, Jin Y, Li L. Ethics: China already has clear stem-cell guidelines. Nature. 440: 992. PMID 16625175 DOI: 10.1038/440992B  0.508
2006 Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI. HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells (Dayton, Ohio). 24: 876-88. PMID 16513761 DOI: 10.1634/Stemcells.2005-0598  0.556
2006 Mali P, Cheng L. Reprogramming somatic cells without fusion or ethical confusion Regenerative Medicine. 1: 837-840. DOI: 10.2217/17460751.1.6.837  0.778
2006 Chen G, Ye Z, Yu X, Brodsky RA, Cheng L. Developmental Potentials of Human Embryonic Stem Cells Lacking PIG-A and GPI-Anchored Proteins. Blood. 108: 1314-1314. DOI: 10.1182/Blood.V108.11.1314.1314  0.78
2006 Zhou BY, Ye Z, Gao P, Cheng L. 100. Inducible and Reversible Transgene Expression in Human Stem Cells Stably Transduced by Novel Lentiviral Vectors Molecular Therapy. 13: S41. DOI: 10.1016/J.Ymthe.2006.08.119  0.765
2005 Wang K, Xue T, Tsang SY, Van Huizen R, Wong CW, Lai KW, Ye Z, Cheng L, Au KW, Zhang J, Li GR, Lau CP, Tse HF, Li RA. Electrophysiological properties of pluripotent human and mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1526-34. PMID 16091557 DOI: 10.1634/Stemcells.2004-0299  0.68
2005 Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1489-501. PMID 16002782 DOI: 10.1634/Stemcells.2005-0034  0.715
2005 Chou WC, Chen HY, Yu SL, Cheng L, Yang PC, Dang CV. Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation. Blood. 106: 304-10. PMID 15761015 DOI: 10.1182/Blood-2005-01-0241  0.339
2004 Zhan X, Dravid G, Ye Z, Hammond H, Shamblott M, Gearhart J, Cheng L. Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet (London, England). 364: 163-71. PMID 15246729 DOI: 10.1016/S0140-6736(04)16629-4  0.735
2004 Dunlap S, Yu X, Cheng L, Civin CI, Alani RM. High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system. The Journal of Investigative Dermatology. 122: 549-51. PMID 15009744 DOI: 10.1046/J.0022-202X.2004.22214.X  0.378
2004 Pan F, Ye Z, Cheng L, Liu JO. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). The Journal of Biological Chemistry. 279: 14477-80. PMID 14722108 DOI: 10.1074/Jbc.C300487200  0.637
2004 Li L, Piloto O, Kim K, Ye Z, Nguyen B, Yu X, Levis M, Cheng L, Small D. FLT3/ITD Expression Increases Expansion, Survival and Entry into Cell Cycle of Human Hematopoietic Stem Cells. Blood. 104: 484-484. DOI: 10.1182/Blood.V104.11.484.484  0.767
2003 Ye Z, Cheng L. Making lentiviral vectors more powerful and universal. Discovery Medicine. 3: 48-9. PMID 20704865  0.714
2003 Zhou X, Cui Y, Huang X, Yu Z, Thomas AM, Ye Z, Pardoll DM, Jaffee EM, Cheng L. Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells. Human Gene Therapy. 14: 1089-105. PMID 12885348 DOI: 10.1089/104303403322124800  0.71
2003 Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L. Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 827-38. PMID 12788657 DOI: 10.1016/S1525-0016(03)00104-7  0.735
2003 Cui Y, Kelleher E, Straley E, Fuchs E, Gorski K, Levitsky H, Borrello I, Civin CI, Schoenberger SP, Cheng L, Pardoll DM, Whartenby KA. Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells. Nature Medicine. 9: 952-8. PMID 12778137 DOI: 10.1038/Nm882  0.411
2003 Angelopoulou M, Novelli E, Grove JE, Rinder HM, Civin C, Cheng L, Krause DS. Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Experimental Hematology. 31: 413-20. PMID 12763140 DOI: 10.1016/S0301-472X(03)00042-0  0.543
2003 McCauslin CS, Wine J, Cheng L, Klarmann KD, Candotti F, Clausen PA, Spence SE, Keller JR. In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals Blood. 102: 843-848. PMID 12689938 DOI: 10.1182/blood-2002-12-3859  0.41
2003 Cheng L, Hammond H, Ye Z, Zhan X, Dravid G. Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cells (Dayton, Ohio). 21: 131-42. PMID 12634409 DOI: 10.1634/Stemcells.21-2-131  0.771
2002 Whartenby KA, Straley EE, Kim H, Racke F, Tanavde V, Gorski KS, Cheng L, Pardoll DM, Civin CI. Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation. Blood. 100: 3147-54. PMID 12384412 DOI: 10.1182/Blood-2002-01-0118  0.462
2002 De Miguel MP, Cheng L, Holland EC, Federspiel MJ, Donovan PJ. Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer Proceedings of the National Academy of Sciences of the United States of America. 99: 10458-10463. PMID 12140361 DOI: 10.1073/Pnas.122249399  0.45
2002 Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L. Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood. 99: 399-408. PMID 11781219 DOI: 10.1182/Blood.V99.2.399  0.771
2001 Gao Z, Golob J, Tanavde VM, Civin CI, Hawley RG, Cheng L. High levels of transgene expression following transduction of long-term NOD/SCID-repopulating human cells with a modified lentiviral vector. Stem Cells (Dayton, Ohio). 19: 247-59. PMID 11359950 DOI: 10.1634/Stemcells.19-3-247  0.545
2001 Yang X, Liu H, Li D, Zhou X, Jung WC, Deans AE, Cui Y, Cheng L. Digital optical imaging of green fluorescent proteins for tracking vascular gene expression: feasibility study in rabbit and human cell models. Radiology. 219: 171-5. PMID 11274553 DOI: 10.1148/Radiology.219.1.R01Ap23171  0.347
2001 Shamblott MJ, Axelman J, Littlefield JW, Blumenthal PD, Huggins GR, Cui Y, Cheng L, Gearhart JD. Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro Proceedings of the National Academy of Sciences. 98: 113-118. DOI: 10.1073/Pnas.98.1.113  0.598
2000 Liu X, Rapp N, Deans R, Cheng L. Molecular cloning and chromosomal mapping of a candidate cytokine gene selectively expressed in human CD34+ cells. Genomics. 65: 283-292. PMID 10857752 DOI: 10.1006/Geno.2000.6170  0.427
2000 Novelli EM, Cheng L, Yang Y, Leung W, Ramírez M, Tanavde V, Enger C, Civin CI. Ex vivo culture of cord blood CD34+ cells expands progenitor cell numbers, preserves engraftment capacity in nonobese diabetic/severe combined immunodeficient mice, and enhances retroviral transduction efficiency. Human Gene Therapy. 10: 2927-40. PMID 10609654 DOI: 10.1089/10430349950016348  0.542
2000 Liu X, Rapp N, Deans R, Cheng L. A candidate cytokine gene selectively expressed in human CD34+ cells Experimental Hematology. 28: 63. DOI: 10.1016/S0301-472X(00)00284-8  0.437
2000 Cui Y, Golob J, Huang X, Pardoll D, Cheng L. Specific transgene expression in antigen presenting cells derived from lentivirally transduced hematopoietic stem/progenitor cells Experimental Hematology. 28: 62-63. DOI: 10.1016/S0301-472X(00)00283-6  0.514
1998 Donovan PJ, de Miguel M, Cheng L, Resnick JL. Primordial germ cells, stem cells and testicular cancer. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 106: 134-41. PMID 9524571 DOI: 10.1111/J.1699-0463.1998.Tb01328.X  0.51
1998 Cheng L, Du C, Lavau C, Chen S, Tong J, Chen BP, Scollay R, Hawley RG, Hill B. Sustained Gene Expression in Retrovirally Transduced, Engrafting Human Hematopoietic Stem Cells and Their Lympho-Myeloid Progeny Blood. 92: 83-92. DOI: 10.1182/Blood.V92.1.83.413K09_83_92  0.598
1997 Cheng L, Du C, Murray D, Tong X, Zhang YA, Chen BP, Hawley RG. A GFP reporter system to assess gene transfer and expression in human hematopoietic progenitor cells Gene Therapy. 4: 1013-1022. PMID 9415306 DOI: 10.1038/Sj.Gt.3300507  0.573
1996 Cheng L, Fu J, Tsukamoto A, Hawley RG. Use of green fluorescent protein variants to monitor gene transfer and expression in mammalian cells Nature Biotechnology. 14: 606-609. PMID 9630951 DOI: 10.1038/Nbt0596-606  0.403
1996 Yang TT, Cheng L, Kain SR. Optimized Codon Usage and Chromophore Mutations Provide Enhanced Sensitivity with the Green Fluorescent Protein Nucleic Acids Research. 24: 4592-4593. PMID 8948654 DOI: 10.1093/Nar/24.22.4592  0.302
1992 Resnick JL, Bixler LS, Cheng L, Donovan PJ. Long-term proliferation of mouse primordial germ cells in culture Nature. 359: 550-551. PMID 1383830 DOI: 10.1038/359550A0  0.506
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