Linzhao Cheng - Publications

Affiliations: 
Johns Hopkins University, Baltimore, MD 
Area:
Cell Biology, Molecular Biology

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Cai L, Bai H, Mahairaki V, Gao Y, He C, Wen Y, Jin YC, Wang Y, Pan RL, Qasba A, Ye Z, Cheng L. A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. Stem Cells Translational Medicine. PMID 29164808 DOI: 10.1002/sctm.17-0066  1
2017 Yuan X, Li Z, Baines AC, Gavriilaki E, Ye Z, Wen Z, Braunstein EM, Biesecker LG, Cheng L, Dong X, Brodsky RA. A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model. Plos One. 12: e0174074. PMID 28441409 DOI: 10.1371/journal.pone.0174074  1
2017 Liu S, Ye Z, Gao Y, He C, Williams DW, Moliterno A, Spivak J, Huang H, Cheng L. Generation of human iPSCs from an essential thrombocythemia patient carrying a V501L mutation in the MPL gene. Stem Cell Research. 18: 57-59. PMID 28395806 DOI: 10.1016/j.scr.2016.12.012  1
2016 Bhatt N, Ghosh R, Roy S, Gao Y, Armanios M, Cheng L, Franco S. Robust reprogramming of Ataxia-Telangiectasia patient and carrier erythroid cells to induced pluripotent stem cells. Stem Cell Research. 17: 296-305. PMID 27596957 DOI: 10.1016/j.scr.2016.08.006  0.52
2016 Long H, Miller SF, Strauss C, Zhao C, Cheng L, Ye Z, Griffin K, Te R, Lee H, Chen CC, Lynch M. Antibiotic treatment enhances the genome-wide mutation rate of target cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27091991 DOI: 10.1073/pnas.1601208113  1
2016 Smith C, Ye Z, Cheng L. Genome Editing in Human Pluripotent Stem Cells. Cold Spring Harbor Protocols. 2016: pdb.top086819. PMID 27037079 DOI: 10.1101/pdb.top086819  0.52
2016 Smith C, Ye Z, Cheng L. A Method for Genome Editing in Human Pluripotent Stem Cells. Cold Spring Harbor Protocols. 2016: pdb.prot090217. PMID 27037073 DOI: 10.1101/pdb.prot090217  0.52
2015 Chou BK, Gu H, Gao Y, Dowey SN, Wang Y, Shi J, Li Y, Ye Z, Cheng T, Cheng L. A facile method to establish human induced pluripotent stem cells from adult blood cells under feeder-free and xeno-free culture conditions: a clinically compliant approach. Stem Cells Translational Medicine. 4: 320-32. PMID 25742692 DOI: 10.5966/sctm.2014-0214  1
2015 Liu Y, Wang Y, Gao Y, Forbes JA, Qayyum R, Becker L, Cheng L, Wang ZZ. Efficient generation of megakaryocytes from human induced pluripotent stem cells using food and drug administration-approved pharmacological reagents. Stem Cells Translational Medicine. 4: 309-19. PMID 25713465 DOI: 10.5966/sctm.2014-0183  0.52
2015 Wang J, Wang N, Jin Y, Si J, Tan ZK, Du H, Cheng L, Dai X, Bai S, He H, Ye Z, Lai ML, Friend RH, Huang W. Interfacial control toward efficient and low-voltage perovskite light-emitting diodes. Advanced Materials (Deerfield Beach, Fla.). 27: 2311-6. PMID 25708283 DOI: 10.1002/adma.201405217  1
2015 Huang X, Wang Y, Yan W, Smith C, Ye Z, Wang J, Gao Y, Mendelsohn L, Cheng L. Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation. Stem Cells (Dayton, Ohio). 33: 1470-9. PMID 25702619 DOI: 10.1002/stem.1969  1
2015 All AH, Gharibani P, Gupta S, Bazley FA, Pashai N, Chou BK, Shah S, Resar LM, Cheng L, Gearhart JD, Kerr CL. Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors. Plos One. 10: e0116933. PMID 25635918 DOI: 10.1371/journal.pone.0116933  0.52
2015 Smith C, Abalde-Atristain L, He C, Brodsky BR, Braunstein EM, Chaudhari P, Jang YY, Cheng L, Ye Z. Efficient and allele-specific genome editing of disease loci in human iPSCs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 570-7. PMID 25418680 DOI: 10.1038/mt.2014.226  1
2014 Cai J, Miao X, Li Y, Smith C, Tsang K, Cheng L, Wang QF. Whole-genome sequencing identifies genetic variances in culture-expanded human mesenchymal stem cells. Stem Cell Reports. 3: 227-33. PMID 25254336 DOI: 10.1016/j.stemcr.2014.05.019  0.52
2014 Wen Z, Nguyen HN, Guo Z, Lalli MA, Wang X, Su Y, Kim NS, Yoon KJ, Shin J, Zhang C, Makri G, Nauen D, Yu H, Guzman E, Chiang CH, ... ... Cheng L, et al. Synaptic dysregulation in a human iPS cell model of mental disorders. Nature. 515: 414-8. PMID 25132547 DOI: 10.1038/nature13716  0.52
2014 Connelly JP, Kwon EM, Gao Y, Trivedi NS, Elkahloun AG, Horwitz MS, Cheng L, Liu PP. Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects. Blood. 124: 1926-30. PMID 25114263 DOI: 10.1182/blood-2014-01-550525  0.52
2014 Smith C, Gore A, Yan W, Abalde-Atristain L, Li Z, He C, Wang Y, Brodsky RA, Zhang K, Cheng L, Ye Z. Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs. Cell Stem Cell. 15: 12-3. PMID 24996165 DOI: 10.1016/j.stem.2014.06.011  1
2014 Huang K, Shen Y, Xue Z, Bibikova M, April C, Liu Z, Cheng L, Nagy A, Pellegrini M, Fan JB, Fan G. A panel of CpG methylation sites distinguishes human embryonic stem cells and induced pluripotent stem cells. Stem Cell Reports. 2: 36-43. PMID 24511466 DOI: 10.1016/j.stemcr.2013.11.003  0.52
2014 Shah S, Huang X, Cheng L. Concise review: stem cell-based approaches to red blood cell production for transfusion. Stem Cells Translational Medicine. 3: 346-55. PMID 24361925 DOI: 10.5966/sctm.2013-0054  0.6
2014 Belet S, Fieremans N, Yuan X, Van Esch H, Verbeeck J, Ye Z, Cheng L, Brodsky BR, Hu H, Kalscheuer VM, Brodsky RA, Froyen G. Early frameshift mutation in PIGA identified in a large XLID family without neonatal lethality. Human Mutation. 35: 350-5. PMID 24357517 DOI: 10.1002/humu.22498  1
2014 Wang Y, Cheng L, Gerecht S. Efficient and scalable expansion of human pluripotent stem cells under clinically compliant settings: a view in 2013. Annals of Biomedical Engineering. 42: 1357-72. PMID 24132657 DOI: 10.1007/s10439-013-0921-4  0.4
2014 Ye Z, Liu CF, Lanikova L, Dowey SN, He C, Huang X, Brodsky RA, Spivak JL, Prchal JT, Cheng L. Differential sensitivity to JAK inhibitory drugs by isogenic human erythroblasts and hematopoietic progenitors generated from patient-specific induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 32: 269-78. PMID 24105986 DOI: 10.1002/stem.1545  0.52
2014 Huang X, Shah S, Wang J, Ye Z, Dowey SN, Tsang KM, Mendelsohn LG, Kato GJ, Kickler TS, Cheng L. Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 451-63. PMID 24002691 DOI: 10.1038/mt.2013.201  1
2014 Yu Y, Liang D, Tian Q, Chen X, Jiang B, Chou BK, Hu P, Cheng L, Gao P, Li J, Wang G. Stimulation of somatic cell reprogramming by ERas-Akt-FoxO1 signaling axis. Stem Cells (Dayton, Ohio). 32: 349-63. PMID 23765875 DOI: 10.1002/stem.1447  0.76
2013 Yuan X, Braunstein EM, Ye Z, Liu CF, Chen G, Zou J, Cheng L, Brodsky RA. Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells. Stem Cells Translational Medicine. 2: 819-29. PMID 24113066 DOI: 10.5966/sctm.2013-0069  1
2013 Chou BK, Cheng L. And then there were none: no need for pluripotency factors to induce reprogramming. Cell Stem Cell. 13: 261-2. PMID 24012365 DOI: 10.1016/j.stem.2013.08.004  0.76
2013 Wang Y, Chou BK, Dowey S, He C, Gerecht S, Cheng L. Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions. Stem Cell Research. 11: 1103-16. PMID 23973800 DOI: 10.1016/j.scr.2013.07.011  0.76
2013 Yan W, Smith C, Cheng L. Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing. Scientific Reports. 3: 2376. PMID 23921522 DOI: 10.1038/srep02376  0.52
2013 Kusuma S, Shen YI, Hanjaya-Putra D, Mali P, Cheng L, Gerecht S. Self-organized vascular networks from human pluripotent stem cells in a synthetic matrix. Proceedings of the National Academy of Sciences of the United States of America. 110: 12601-6. PMID 23858432 DOI: 10.1073/pnas.1306562110  0.88
2013 Ran D, Lam K, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. Response: the role of RUNX1 isoforms in hematopoietic commitment of human pluripotent stem cells. Blood. 121: 5252-3. PMID 23813938 DOI: 10.1182/blood-2013-04-494914  0.52
2013 Chou BK, Ye Z, Cheng L. Generation and homing of iPSC-derived hematopoietic cells in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1292-3. PMID 23812546 DOI: 10.1038/mt.2013.129  1
2013 Ran D, Shia WJ, Lo MC, Fan JB, Knorr DA, Ferrell PI, Ye Z, Yan M, Cheng L, Kaufman DS, Zhang DE. RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood. 121: 2882-90. PMID 23372166 DOI: 10.1182/blood-2012-08-451641  1
2012 Wei KL, Yang YJ, Yao YJ, Du LZ, Wang QH, Wang RH, Wang L, Lin Y, Liu J, Wang H, Wang XL, Wu HM, Wu K, Chen Y, Zhong XY, ... ... Cheng LX, et al. Epidemiologic survey on hospitalized neonates in China. Translational Pediatrics. 1: 15-22. PMID 26835259 DOI: 10.3978/j.issn.2224-4336.2011.10.01  0.4
2012 Dowey SN, Huang X, Chou BK, Ye Z, Cheng L. Generation of integration-free human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nature Protocols. 7: 2013-21. PMID 23080273 DOI: 10.1038/nprot.2012.121  1
2012 Ye Z, Chou BK, Cheng L. Promise and challenges of human iPSC-based hematologic disease modeling and treatment. International Journal of Hematology. 95: 601-9. PMID 22619021 DOI: 10.1007/s12185-012-1095-9  1
2012 Khatau SB, Kusuma S, Hanjaya-Putra D, Mali P, Cheng L, Lee JS, Gerecht S, Wirtz D. The differential formation of the LINC-mediated perinuclear actin cap in pluripotent and somatic cells. Plos One. 7: e36689. PMID 22574215 DOI: 10.1371/journal.pone.0036689  0.52
2012 Cheng L, Hansen NF, Zhao L, Du Y, Zou C, Donovan FX, Chou BK, Zhou G, Li S, Dowey SN, Ye Z, Chandrasekharappa SC, Yang H, Mullikin JC, et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell. 10: 337-44. PMID 22385660 DOI: 10.1016/j.stem.2012.01.005  1
2012 Johnston JJ, Gropman AL, Sapp JC, Teer JK, Martin JM, Liu CF, Yuan X, Ye Z, Cheng L, Brodsky RA, Biesecker LG. The phenotype of a germline mutation in PIGA: the gene somatically mutated in paroxysmal nocturnal hemoglobinuria. American Journal of Human Genetics. 90: 295-300. PMID 22305531 DOI: 10.1016/j.ajhg.2011.11.031  1
2012 Zou C, Chou BK, Dowey SN, Tsang K, Huang X, Liu CF, Smith C, Yen J, Mali P, Zhang YA, Cheng L, Ye Z. Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines. Stem Cells and Development. 21: 2298-311. PMID 22225458 DOI: 10.1089/scd.2011.0688  1
2012 Mali P, Cheng L. Concise review: Human cell engineering: cellular reprogramming and genome editing. Stem Cells (Dayton, Ohio). 30: 75-81. PMID 21905170 DOI: 10.1002/stem.735  0.88
2011 Zou J, Mali P, Huang X, Dowey SN, Cheng L. Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease. Blood. 118: 4599-608. PMID 21881051 DOI: 10.1182/blood-2011-02-335554  0.88
2011 Choi SM, Liu H, Chaudhari P, Kim Y, Cheng L, Feng J, Sharkis S, Ye Z, Jang YY. Reprogramming of EBV-immortalized B-lymphocyte cell lines into induced pluripotent Stem cells Blood. 118: 1801-1805. PMID 21628406 DOI: 10.1182/blood-2011-03-340620  0.52
2011 Jang YY, Ye Z, Cheng L. Molecular imaging and stem cell research. Molecular Imaging. 10: 111-22. PMID 21439256  1
2011 Zou J, Sweeney CL, Chou BK, Choi U, Pan J, Wang H, Dowey SN, Cheng L, Malech HL. Oxidase-deficient neutrophils from X-linked chronic granulomatous disease iPS cells: functional correction by zinc finger nuclease-mediated safe harbor targeting. Blood. 117: 5561-72. PMID 21411759 DOI: 10.1182/blood-2010-12-328161  0.52
2011 Broxmeyer HE, Lee MR, Hangoc G, Cooper S, Prasain N, Kim YJ, Mallett C, Ye Z, Witting S, Cornetta K, Cheng L, Yoder MC. Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood. Blood. 117: 4773-7. PMID 21393480 DOI: 10.1182/blood-2011-01-330514  1
2011 Wang B, Zhang YB, Zhang F, Lin H, Wang X, Wan N, Ye Z, Weng H, Zhang L, Li X, Yan J, Wang P, Wu T, Cheng L, Wang J, et al. On the origin of Tibetans and their genetic basis in adapting high-altitude environments. Plos One. 6: e17002. PMID 21386899 DOI: 10.1371/journal.pone.0017002  1
2011 Chou BK, Mali P, Huang X, Ye Z, Dowey SN, Resar LM, Zou C, Zhang YA, Tong J, Cheng L. Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Research. 21: 518-29. PMID 21243013 DOI: 10.1038/cr.2011.12  1
2010 Li D, Zhou J, Wang L, Shin ME, Su P, Lei X, Kuang H, Guo W, Yang H, Cheng L, Tanaka TS, Leckband DE, Reynolds AB, Duan E, Wang F. Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. The Journal of Cell Biology. 191: 631-44. PMID 20974810 DOI: 10.1083/jcb.201006094  0.52
2010 Ohm JE, Mali P, Van Neste L, Berman DM, Liang L, Pandiyan K, Briggs KJ, Zhang W, Argani P, Simons B, Yu W, Matsui W, Van Criekinge W, Rassool FV, Zambidis E, ... ... Cheng L, et al. Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Research. 70: 7662-73. PMID 20841480 DOI: 10.1158/0008-5472.CAN-10-1361  0.88
2010 Swistowski A, Peng J, Liu Q, Mali P, Rao MS, Cheng L, Zeng X. Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. Stem Cells (Dayton, Ohio). 28: 1893-904. PMID 20715183 DOI: 10.1002/stem.499  0.52
2010 Ye Z, Cheng L. Potential of human induced pluripotent stem cells derived from blood and other postnatal cell types. Regenerative Medicine. 5: 521-30. PMID 20632856 DOI: 10.2217/rme.10.38  1
2010 Mali P, Ye Z, Chou BK, Yen J, Cheng L. An improved method for generating and identifying human induced pluripotent stem cells. Methods in Molecular Biology (Clifton, N.J.). 636: 191-205. PMID 20336524 DOI: 10.1007/978-1-60761-691-7_12  1
2010 Mali P, Chou BK, Yen J, Ye Z, Zou J, Dowey S, Brodsky RA, Ohm JE, Yu W, Baylin SB, Yusa K, Bradley A, Meyers DJ, Mukherjee C, Cole PA, ... Cheng L, et al. Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (Dayton, Ohio). 28: 713-20. PMID 20201064 DOI: 10.1002/stem.402  1
2010 Zou J, Cochran R, Cheng L. Double knockouts in human embryonic stem cells. Cell Research. 20: 250-2. PMID 20190774 DOI: 10.1038/cr.2010.29  0.52
2009 Ye Z, Zhan H, Mali P, Dowey S, Williams DM, Jang YY, Dang CV, Spivak JL, Moliterno AR, Cheng L. Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders Blood. 114: 5473-5480. PMID 19797525 DOI: 10.1182/blood-2009-04-217406  0.52
2009 Zou J, Maeder ML, Mali P, Pruett-Miller SM, Thibodeau-Beganny S, Chou BK, Chen G, Ye Z, Park IH, Daley GQ, Porteus MH, Joung JK, Cheng L. Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 5: 97-110. PMID 19540188 DOI: 10.1016/j.stem.2009.05.023  0.52
2009 Pomper MG, Hammond H, Yu X, Ye Z, Foss CA, Lin DD, Fox JJ, Cheng L. Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Research. 19: 370-9. PMID 19114988 DOI: 10.1038/cr.2008.329  0.52
2009 Savage WJ, Barber JP, Mukhina GL, Hu R, Chen G, Matsui W, Thoburn C, Hess AD, Cheng L, Jones RJ, Brodsky RA. Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH. Experimental Hematology. 37: 42-51. PMID 19013003 DOI: 10.1016/j.exphem.2008.09.002  0.52
2009 Durai M, Krueger C, Ye Z, Cheng L, Mackensen A, Oelke M, Schneck JP. In vivo functional efficacy of tumor-specific T cells expanded using HLA-Ig based artificial antigen presenting cells (aAPC). Cancer Immunology, Immunotherapy : Cii. 58: 209-20. PMID 18563409 DOI: 10.1007/s00262-008-0542-1  0.52
2008 Hwang NS, Varghese S, Lee HJ, Zhang Z, Ye Z, Bae J, Cheng L, Elisseeff J. In vivo commitment and functional tissue regeneration using human embryonic stem cell-derived mesenchymal cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 20641-6. PMID 19095799 DOI: 10.1073/pnas.0809680106  1
2008 Hillion J, Dhara S, Sumter TF, Mukherjee M, Di Cello F, Belton A, Turkson J, Jaganathan S, Cheng L, Ye Z, Jove R, Aplan P, Lin YW, Wertzler K, Reeves R, et al. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies? Cancer Research. 68: 10121-7. PMID 19074878 DOI: 10.1158/0008-5472.CAN-08-2121  0.52
2008 Wu Z, Zhang W, Chen G, Cheng L, Liao J, Jia N, Gao Y, Dai H, Yuan J, Cheng L, Xiao L. Combinatorial signals of activin/nodal and bone morphogenic protein regulate the early lineage segregation of human embryonic stem cells. The Journal of Biological Chemistry. 283: 24991-5002. PMID 18596037 DOI: 10.1074/jbc.M803893200  0.52
2008 Mali P, Ye Z, Hommond HH, Yu X, Lin J, Chen G, Zou J, Cheng L. Improved efficiency and pace of generating induced pluripotent stem cells from human adult and fetal fibroblasts. Stem Cells (Dayton, Ohio). 26: 1998-2005. PMID 18511599 DOI: 10.1634/stemcells.2008-0346  1
2008 Yu X, Zou J, Ye Z, Hammond H, Chen G, Tokunaga A, Mali P, Li YM, Civin C, Gaiano N, Cheng L. Notch signaling activation in human embryonic stem cells is required for embryonic, but not trophoblastic, lineage commitment. Cell Stem Cell. 2: 461-71. PMID 18462696 DOI: 10.1016/j.stem.2008.03.001  0.52
2008 Chen G, Ye Z, Yu X, Zou J, Mali P, Brodsky RA, Cheng L. Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins. Cell Stem Cell. 2: 345-55. PMID 18397754 DOI: 10.1016/j.stem.2008.02.004  1
2008 Cheng L, Xiao L, Zeng F, Zhang YA. Stem cells shine in Shanghai. Cell Stem Cell. 2: 34-7. PMID 18371419 DOI: 10.1016/j.stem.2007.12.010  0.6
2008 Ye Z, Yu X, Cheng L. Lentiviral gene transduction of mouse and human stem cells. Methods in Molecular Biology (Clifton, N.J.). 430: 243-53. PMID 18370304 DOI: 10.1007/978-1-59745-182-6_17  1
2008 Cheng L. More new lines of human parthenogenetic embryonic stem cells Cell Research. 18: 215-217. PMID 18246085 DOI: 10.1038/cr.2008.19  0.52
2007 Baba S, Cho SY, Ye Z, Cheng L, Engles JM, Wahl RL. How reproducible is bioluminescent imaging of tumor cell growth? Single time point versus the dynamic measurement approach. Molecular Imaging. 6: 315-22. PMID 18092516 DOI: 10.2310/7290.2007.00031  0.52
2007 Gao P, Zhang H, Dinavahi R, Li F, Xiang Y, Raman V, Bhujwalla ZM, Felsher DW, Cheng L, Pevsner J, Lee LA, Semenza GL, Dang CV. HIF-dependent antitumorigenic effect of antioxidants in vivo. Cancer Cell. 12: 230-8. PMID 17785204 DOI: 10.1016/j.ccr.2007.08.004  0.52
2007 Qian DZ, Wei YF, Wang X, Kato Y, Cheng L, Pili R. Antitumor activity of the histone deacetylase inhibitor MS-275 in prostate cancer models. The Prostate. 67: 1182-93. PMID 17520666 DOI: 10.1002/pros.20611  0.52
2007 Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D. FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells. British Journal of Haematology. 137: 64-75. PMID 17359372 DOI: 10.1111/j.1365-2141.2007.06525.x  1
2007 Cai L, Ye Z, Zhou BY, Mali P, Zhou C, Cheng L. Promoting human embryonic stem cell renewal or differentiation by modulating Wnt signal and culture conditions. Cell Research. 17: 62-72. PMID 17211448 DOI: 10.1038/sj.cr.7310138  1
2007 Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ, Watkins DN, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nature Genetics. 39: 237-42. PMID 17211412 DOI: 10.1038/ng1972  0.56
2007 Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L. Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells (Dayton, Ohio). 25: 779-89. PMID 17158240 DOI: 10.1634/stemcells.2006-0128  1
2006 Dravid G, Hammond H, Cheng L. Culture of human embryonic stem cells on human and mouse feeder cells. Methods in Molecular Biology (Clifton, N.J.). 331: 91-104. PMID 16881511 DOI: 10.1385/1-59745-046-4:91  0.36
2006 Litvinov IV, Antony L, Dalrymple SL, Becker R, Cheng L, Isaacs JT. PC3, but not DU145, human prostate cancer cells retain the coregulators required for tumor suppressor ability of androgen receptor. The Prostate. 66: 1329-38. PMID 16835890 DOI: 10.1002/pros.20483  0.52
2006 Cheng L, Qiu RZ, Deng H, Zhang YA, Jin Y, Li L. Ethics: China already has clear stem-cell guidelines. Nature. 440: 992. PMID 16625175 DOI: 10.1038/440992b  0.6
2006 Yu X, Alder JK, Chun JH, Friedman AD, Heimfeld S, Cheng L, Civin CI. HES1 inhibits cycling of hematopoietic progenitor cells via DNA binding. Stem Cells (Dayton, Ohio). 24: 876-88. PMID 16513761 DOI: 10.1634/stemcells.2005-0598  0.56
2005 Wang K, Xue T, Tsang SY, Van Huizen R, Wong CW, Lai KW, Ye Z, Cheng L, Au KW, Zhang J, Li GR, Lau CP, Tse HF, Li RA. Electrophysiological properties of pluripotent human and mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1526-34. PMID 16091557 DOI: 10.1634/stemcells.2004-0299  0.52
2005 Du X, Qiu B, Zhan X, Kolmakova A, Gao F, Hofmann LV, Cheng L, Chatterjee S, Yang X. Radiofrequency-enhanced vascular gene transduction and expression for intravascular MR imaging-guided therapy: feasibility study in pigs. Radiology. 236: 939-44. PMID 16040894 DOI: 10.1148/radiol.2363041021  0.36
2005 Dravid G, Ye Z, Hammond H, Chen G, Pyle A, Donovan P, Yu X, Cheng L. Defining the role of Wnt/beta-catenin signaling in the survival, proliferation, and self-renewal of human embryonic stem cells. Stem Cells (Dayton, Ohio). 23: 1489-501. PMID 16002782 DOI: 10.1634/stemcells.2005-0034  1
2005 Chou WC, Chen HY, Yu SL, Cheng L, Yang PC, Dang CV. Arsenic suppresses gene expression in promyelocytic leukemia cells partly through Sp1 oxidation. Blood. 106: 304-10. PMID 15761015 DOI: 10.1182/blood-2005-01-0241  0.52
2004 Chen HH, Zhan X, Kumar A, Du X, Hammond H, Cheng L, Yang X. Detection of dual-gene expression in arteries using an optical imaging method. Journal of Biomedical Optics. 9: 1223-9. PMID 15568943 DOI: 10.1117/1.1803842  0.36
2004 Zhan X, Dravid G, Ye Z, Hammond H, Shamblott M, Gearhart J, Cheng L. Functional antigen-presenting leucocytes derived from human embryonic stem cells in vitro. Lancet (London, England). 364: 163-71. PMID 15246729 DOI: 10.1016/S0140-6736(04)16629-4  1
2004 Dunlap S, Yu X, Cheng L, Civin CI, Alani RM. High-efficiency stable gene transduction in primary human melanocytes using a lentiviral expression system. The Journal of Investigative Dermatology. 122: 549-51. PMID 15009744 DOI: 10.1046/j.0022-202X.2004.22214.x  0.52
2004 Pan F, Ye Z, Cheng L, Liu JO. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). The Journal of Biological Chemistry. 279: 14477-80. PMID 14722108 DOI: 10.1074/jbc.C300487200  0.52
2003 Ye Z, Cheng L. Making lentiviral vectors more powerful and universal. Discovery Medicine. 3: 48-9. PMID 20704865  1
2003 Zhou X, Cui Y, Huang X, Yu Z, Thomas AM, Ye Z, Pardoll DM, Jaffee EM, Cheng L. Lentivirus-mediated gene transfer and expression in established human tumor antigen-specific cytotoxic T cells and primary unstimulated T cells. Human Gene Therapy. 14: 1089-105. PMID 12885348 DOI: 10.1089/104303403322124800  1
2003 Yu X, Zhan X, D'Costa J, Tanavde VM, Ye Z, Peng T, Malehorn MT, Yang X, Civin CI, Cheng L. Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Molecular Therapy : the Journal of the American Society of Gene Therapy. 7: 827-38. PMID 12788657  1
2003 Cui Y, Kelleher E, Straley E, Fuchs E, Gorski K, Levitsky H, Borrello I, Civin CI, Schoenberger SP, Cheng L, Pardoll DM, Whartenby KA. Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells. Nature Medicine. 9: 952-8. PMID 12778137 DOI: 10.1038/nm882  0.52
2003 McCauslin CS, Wine J, Cheng L, Klarmann KD, Candotti F, Clausen PA, Spence SE, Keller JR. In vivo retroviral gene transfer by direct intrafemoral injection results in correction of the SCID phenotype in Jak3 knock-out animals Blood. 102: 843-848. PMID 12689938 DOI: 10.1182/blood-2002-12-3859  0.52
2003 Cheng L, Hammond H, Ye Z, Zhan X, Dravid G. Human adult marrow cells support prolonged expansion of human embryonic stem cells in culture. Stem Cells (Dayton, Ohio). 21: 131-42. PMID 12634409 DOI: 10.1634/stemcells.21-2-131  1
2002 De Miguel MP, Cheng L, Holland EC, Federspiel MJ, Donovan PJ. Dissection of the c-Kit signaling pathway in mouse primordial germ cells by retroviral-mediated gene transfer Proceedings of the National Academy of Sciences of the United States of America. 99: 10458-10463. PMID 12140361 DOI: 10.1073/pnas.122249399  0.52
2002 Cui Y, Golob J, Kelleher E, Ye Z, Pardoll D, Cheng L. Targeting transgene expression to antigen-presenting cells derived from lentivirus-transduced engrafting human hematopoietic stem/progenitor cells. Blood. 99: 399-408. PMID 11781219 DOI: 10.1182/blood.V99.2.399  0.52
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