Russ P. Carstens - Publications

University of Pennsylvania, Philadelphia, PA, United States 
Molecular Biology, Cell Biology, Bioinformatics Biology

33/49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP. Cleft lip and cleft palate (CL/P) in KO mice is associated with alterations in epithelial-mesenchymal crosstalk. Development (Cambridge, England). PMID 32253237 DOI: 10.1242/dev.187369  0.52
2019 Zhang Z, Pan Z, Ying Y, Xie Z, Adhikari S, Phillips J, Carstens RP, Black DL, Wu Y, Xing Y. Deep-learning augmented RNA-seq analysis of transcript splicing. Nature Methods. 16: 307-310. PMID 30923373 DOI: 10.1038/s41592-019-0351-9  0.52
2017 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ. ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Developmental Cell. 43: 318-331.e5. PMID 29107558 DOI: 10.1016/j.devcel.2017.09.026  0.52
2016 Bebee TW, Sims-Lucas S, Park JW, Bushnell D, Cieply B, Xing Y, Bates CM, Carstens RP. Ablation of the epithelial-specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 27404344 DOI: 10.1002/dvdy.24431  0.52
2016 Cieply B, Park JW, Nakauka-Ddamba A, Bebee TW, Guo Y, Shang X, Lengner CJ, Xing Y, Carstens RP. Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins. Cell Reports. PMID 27050523 DOI: 10.1016/j.celrep.2016.03.025  0.52
2016 Yang Y, Park JW, Bebee TW, Warzecha CC, Guo Y, Shang X, Xing Y, Carstens RP. Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during the epithelial to mesenchymal transition. Molecular and Cellular Biology. PMID 27044866 DOI: 10.1128/MCB.00019-16  1
2015 Bhate A, Parker DJ, Bebee TW, Ahn J, Arif W, Rashan EH, Chorghade S, Chau A, Lee JH, Anakk S, Carstens RP, Xiao X, Kalsotra A. ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation. Nature Communications. 6: 8768. PMID 26531099 DOI: 10.1038/ncomms9768  0.52
2015 Bebee TW, Park JW, Sheridan KI, Warzecha CC, Cieply BW, Rohacek AM, Xing Y, Carstens RP. The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development. Elife. 4. PMID 26371508 DOI: 10.7554/eLife.08954  0.52
2015 Cieply B, Carstens RP. Functional roles of alternative splicing factors in human disease. Wiley Interdisciplinary Reviews. Rna. 6: 311-26. PMID 25630614 DOI: 10.1002/wrna.1276  0.52
2014 Bebee TW, Cieply BW, Carstens RP. Genome-wide activities of RNA binding proteins that regulate cellular changes in the epithelial to mesenchymal transition (EMT). Advances in Experimental Medicine and Biology. 825: 267-302. PMID 25201109 DOI: 10.1007/978-1-4939-1221-6_8  0.52
2013 Heinicke LA, Nabet B, Shen S, Jiang P, van Zalen S, Cieply B, Russell JE, Xing Y, Carstens RP. The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation. Plos One. 8: e78031. PMID 24250749 DOI: 10.1371/journal.pone.0078031  0.52
2013 Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, ... ... Carstens RP, et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature. 499: 172-7. PMID 23846655 DOI: 10.1038/nature12311  0.52
2012 Di Modugno F, Iapicca P, Boudreau A, Mottolese M, Terrenato I, Perracchio L, Carstens RP, Santoni A, Bissell MJ, Nisticò P. Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors. Proceedings of the National Academy of Sciences of the United States of America. 109: 19280-5. PMID 23129656 DOI: 10.1073/pnas.1214394109  0.52
2012 Warzecha CC, Carstens RP. Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT). Seminars in Cancer Biology. 22: 417-27. PMID 22548723 DOI: 10.1016/j.semcancer.2012.04.003  1
2012 Warzecha CC, Hovhannisyan R, Carstens RP. Dynamic fluorescent and luminescent reporters for cell-based splicing screens. Methods in Molecular Biology (Clifton, N.J.). 867: 273-87. PMID 22454068 DOI: 10.1007/978-1-61779-767-5_18  1
2012 Shen S, Park JW, Huang J, Dittmar KA, Lu ZX, Zhou Q, Carstens RP, Xing Y. MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data. Nucleic Acids Research. 40: e61. PMID 22266656 DOI: 10.1093/nar/gkr1291  0.52
2010 Warzecha CC, Jiang P, Amirikian K, Dittmar KA, Lu H, Shen S, Guo W, Xing Y, Carstens RP. An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. The Embo Journal. 29: 3286-300. PMID 20711167 DOI: 10.1038/emboj.2010.195  0.52
2010 Shen S, Warzecha CC, Carstens RP, Xing Y. MADS+: discovery of differential splicing events from Affymetrix exon junction array data. Bioinformatics (Oxford, England). 26: 268-9. PMID 19933160 DOI: 10.1093/bioinformatics/btp643  1
2009 Warzecha CC, Shen S, Xing Y, Carstens RP. The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. Rna Biology. 6: 546-62. PMID 19829082  1
2009 Nabet B, Tsai A, Tobias JW, Carstens RP. Identification of a putative network of actin-associated cytoskeletal proteins in glomerular podocytes defined by co-purified mRNAs. Plos One. 4: e6491. PMID 19652713 DOI: 10.1371/journal.pone.0006491  0.52
2009 Warzecha CC, Sato TK, Nabet B, Hogenesch JB, Carstens RP. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Molecular Cell. 33: 591-601. PMID 19285943 DOI: 10.1016/j.molcel.2009.01.025  0.52
2007 Hovhannisyan RH, Carstens RP. Heterogeneous ribonucleoprotein m is a splicing regulatory protein that can enhance or silence splicing of alternatively spliced exons. The Journal of Biological Chemistry. 282: 36265-74. PMID 17959601 DOI: 10.1074/jbc.M704188200  0.6
2007 Ji X, Kong J, Carstens RP, Liebhaber SA. The 3' untranslated region complex involved in stabilization of human alpha-globin mRNA assembles in the nucleus and serves an independent role as a splice enhancer. Molecular and Cellular Biology. 27: 3290-302. PMID 17325043 DOI: 10.1128/MCB.02289-05  0.52
2006 Tsai A, Carstens RP. An optimized protocol for protein purification in cultured mammalian cells using a tandem affinity purification approach. Nature Protocols. 1: 2820-7. PMID 17406540 DOI: 10.1038/nprot.2006.371  0.52
2006 Newman EA, Muh SJ, Hovhannisyan RH, Warzecha CC, Jones RB, McKeehan WL, Carstens RP. Identification of RNA-binding proteins that regulate FGFR2 splicing through the use of sensitive and specific dual color fluorescence minigene assays. Rna (New York, N.Y.). 12: 1129-41. PMID 16603716 DOI: 10.1261/rna.34906  0.52
2006 Geng J, Carstens RP. Two methods for improved purification of full-length mammalian proteins that have poor expression and/or solubility using standard Escherichia coli procedures. Protein Expression and Purification. 48: 142-50. PMID 16529945 DOI: 10.1016/j.pep.2006.01.021  0.52
2006 Hovhannisyan RH, Warzecha CC, Carstens RP. Characterization of sequences and mechanisms through which ISE/ISS-3 regulates FGFR2 splicing. Nucleic Acids Research. 34: 373-85. PMID 16410617 DOI: 10.1093/nar/gkj407  1
2005 Hovhannisyan RH, Carstens RP. A novel intronic cis element, ISE/ISS-3, regulates rat fibroblast growth factor receptor 2 splicing through activation of an upstream exon and repression of a downstream exon containing a noncanonical branch point sequence. Molecular and Cellular Biology. 25: 250-63. PMID 15601847 DOI: 10.1128/MCB.25.1.250-263.2005  0.6
2002 Muh SJ, Hovhannisyan RH, Carstens RP. A Non-sequence-specific double-stranded RNA structural element regulates splicing of two mutually exclusive exons of fibroblast growth factor receptor 2 (FGFR2). The Journal of Biological Chemistry. 277: 50143-54. PMID 12393912 DOI: 10.1074/jbc.M207409200  0.6
2001 Jones RB, Carstens RP, Luo Y, McKeehan WL. 5'- and 3'-terminal nucleotides in the FGFR2 ISAR splicing element core have overlapping roles in exon IIIb activation and exon IIIc repression. Nucleic Acids Research. 29: 3557-65. PMID 11522825  0.52
2000 Carstens RP, Wagner EJ, Garcia-Blanco MA. An intronic splicing silencer causes skipping of the IIIb exon of fibroblast growth factor receptor 2 through involvement of polypyrimidine tract binding protein. Molecular and Cellular Biology. 20: 7388-400. PMID 10982855 DOI: 10.1128/MCB.20.19.7388-7400.2000  0.52
1999 Wagner EJ, Carstens RP, Garcia-Blanco MA. A novel isoform ratio switch of the polypyrimidine tract binding protein. Electrophoresis. 20: 1082-6. PMID 10344288 DOI: 10.1002/(SICI)1522-2683(19990101)20:4/5<1082::AID-ELPS1082>3.0.CO;2-#  0.52
1998 Carstens RP, McKeehan WL, Garcia-Blanco MA. An intronic sequence element mediates both activation and repression of rat fibroblast growth factor receptor 2 pre-mRNA splicing. Molecular and Cellular Biology. 18: 2205-17. PMID 9528792  0.52
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2018 Lee S, Cieply B, Yang Y, Peart N, Glaser C, Chan P, Carstens RP. Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity. Cell Reports. 25: 2417-2430.e5. PMID 30485810 DOI: 10.1016/j.celrep.2018.10.097  0.16
2013 Lu H, Liu J, Liu S, Zeng J, Ding D, Carstens RP, Cong Y, Xu X, Guo W. Exo70 isoform switching upon epithelial-mesenchymal transition mediates cancer cell invasion. Developmental Cell. 27: 560-73. PMID 24331928 DOI: 10.1016/j.devcel.2013.10.020  0.16
2018 Cox LL, Cox TC, Moreno Uribe LM, Zhu Y, Richter CT, Nidey N, Standley JM, Deng M, Blue E, Chong JX, Yang Y, Carstens RP, Anand D, Lachke SA, Smith JD, et al. Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate. American Journal of Human Genetics. PMID 29805042 DOI: 10.1016/j.ajhg.2018.04.009  0.12
2017 Yang Y, Carstens RP. Alternative splicing regulates distinct subcellular localization of Epithelial splicing regulatory protein 1 (Esrp1) isoforms. Scientific Reports. 7: 3848. PMID 28634384 DOI: 10.1038/s41598-017-03180-3  0.12
2018 Bangru S, Arif W, Seimetz J, Bhate A, Chen J, Rashan EH, Carstens RP, Anakk S, Kalsotra A. Alternative splicing rewires Hippo signaling pathway in hepatocytes to promote liver regeneration. Nature Structural & Molecular Biology. PMID 30250226 DOI: 10.1038/s41594-018-0129-2  0.04
2016 Murphy D, Cieply B, Carstens R, Ramamurthy V, Stoilov P. The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina. Plos Genetics. 12: e1006256. PMID 27541351 DOI: 10.1371/journal.pgen.1006256  0.04
2020 Carroll SH, Macias Trevino C, Li EB, Kawasaki K, Myers N, Hallett SA, Alhazmi N, Cotney J, Carstens RP, Liao EC. An - regulatory axis controls midface morphogenesis in vertebrates. Development (Cambridge, England). PMID 33234718 DOI: 10.1242/dev.194498  0.01
2020 Wilson N, Lee S, Carstens R, Liao E. Abstract 94 Plastic and Reconstructive Surgery - Global Open. 8: 61. DOI: 10.1097/01.GOX.0000667432.95878.fa  0.01
2018 Guha M, Srinivasan S, Raman P, Jiang Y, Kaufman BA, Taylor D, Dong D, Chakrabarti R, Picard M, Carstens RP, Kijima Y, Feldman M, Avadhani NG. Aggressive triple negative breast cancers have unique molecular signature on the basis of mitochondrial genetic and functional defects. Biochimica Et Biophysica Acta. PMID 29309924 DOI: 10.1016/j.bbadis.2018.01.002  0.01
2014 Carstens RP. Networking in an alternative splicing world. Molecular Cell. 54: 903-4. PMID 24950376 DOI: 10.1016/j.molcel.2014.06.014  0.01
2014 Guha M, Srinivasan S, Ruthel G, Kashina AK, Carstens RP, Mendoza A, Khanna C, Van Winkle T, Avadhani NG. Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells. Oncogene. 33: 5238-50. PMID 24186204 DOI: 10.1038/onc.2013.467  0.01
2009 Hovhannisyan R, Carstens R. Affinity chromatography using 2' fluoro-substituted RNAs for detection of RNA-protein interactions in RNase-rich or RNase-treated extracts. Biotechniques. 46: 95-8. PMID 19317654 DOI: 10.2144/000113067  0.01
2004 Ji X, Kong J, Carstens RP, Liebhaber SA. The -Globin mRNA Stabilization Complex Is Assembled in the Nucleus Supporting CP Integration of Nuclear and Cytoplasmic Controls over -Globin Gene Expression. ααα. Blood. 104: 1205-1205. DOI: 10.1182/blood.v104.11.1205.1205  0.01
1997 Carstens RP, Eaton JV, Krigman HR, Walther PJ, Garcia-Blanco MA. Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer. Oncogene. 15: 3059-65. PMID 9444954 DOI: 10.1038/sj.onc.1201498  0.01
1991 Petty EM, Carstens R, Bale AE. Ornithine transcarbamylase polymorphism detected by PCR introduction of DraI site. Nucleic Acids Research. 19: 690. PMID 2011544 DOI: 10.1093/nar/19.3.690  0.01
1986 Johnson H, Carstens R. Anatomical distribution of colonic carcinomas. Interracial differences in a community hospital population. Cancer. 58: 997-1000. PMID 3719563 DOI: 10.1002/1097-0142(19860815)58:4<997::AID-CNCR2820580435>3.0.CO;2-2  0.01
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