H.C Chan - Publications

Affiliations: 
The Chinese University of Hong Kong, Hong Kong, Hong Kong 
Area:
Oncology, Cell Biology, General Biology

152 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Zhao M, Zhang J, Huang W, Dong J, Guo J, U KP, Weng Z, Liu S, Chan HC, Feng H, Jiang X. CFTR promotes malignant glioma development via up-regulation of Akt/Bcl2-mediated anti-apoptosis pathway. Journal of Cellular and Molecular Medicine. PMID 32463592 DOI: 10.1111/jcmm.15300  0.68
2019 Huang B, Wang B, Yuk-Wai Lee W, Pong U K, Leung KT, Li X, Liu Z, Chen R, Lin JC, Tsang LL, Liu B, Ruan YC, Chan HC, Li G, Jiang X. KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization. Iscience. 21: 375-390. PMID 31704649 DOI: 10.1016/J.Isci.2019.10.041  0.68
2019 Liu M, Liao H, Chen Y, Lin Z, Liu Y, Zhang X, Chan HC, Sun H. Treatment of human T-cell acute lymphoblastic leukemia cells with CFTR inhibitor CFTRinh-172. Leukemia Research. 86: 106225. PMID 31541940 DOI: 10.1016/j.leukres.2019.106225  0.4
2019 Chen JJ, Xiao ZJ, Meng X, Wang Y, Yu MK, Huang WQ, Sun X, Chen H, Duan YG, Jiang X, Wong MP, Chan HC, Zou F, Ruan YC. MRP4 sustains Wnt/β-catenin signaling for pregnancy, endometriosis and endometrial cancer. Theranostics. 9: 5049-5064. PMID 31410201 DOI: 10.7150/thno.32097  0.68
2019 Wong TW, Kan CD, Chiu WT, Fok KL, Ruan YC, Jiang X, Chen J, Kao CC, Chen IY, Lin HC, Chou CH, Lin CW, Yu CK, Tsao S, Lee YP, ... Chan HC, et al. Progenitor Cells Derived from Drain Waste Product of Open-Heart Surgery in Children. Journal of Clinical Medicine. 8. PMID 31336927 DOI: 10.3390/jcm8071028  0.68
2019 Guo M, Zhou C, Xu G, Tang L, Ruan Y, Yu Y, Lin X, Wu D, Chen H, Yu P, Jin L, Wang Y, Wu Y, Ullah K, Rahman TU, ... ... Chan HC, et al. An alternative splicing variant of mineralocorticoid receptor discovered in preeclampsia tissues and its effect on endothelial dysfunction. Science China. Life Sciences. PMID 31197761 DOI: 10.1007/s11427-018-9535-9  0.68
2018 Sun X, Guo JH, Zhang D, Chen JJ, Lin WY, Huang Y, Chen H, Huang WQ, Liu Y, Tsang LL, Yu MK, Chung YW, Jiang X, Huang H, Chan HC, et al. Activation of the epithelial sodium channel (ENaC) leads to cytokine profile shift to pro-inflammatory in labor. Embo Molecular Medicine. PMID 30154237 DOI: 10.15252/emmm.201808868  0.68
2018 Liao H, Chen Y, Yulong L, Xue S, Liu M, Lin Z, Liu Y, Chan HC, Zhang X, Sun H. CFTR is required for the migration of Primordial Germ Cells during zebrafish early embryogenesis. Reproduction (Cambridge, England). PMID 29930176 DOI: 10.1530/REP-17-0681  0.4
2018 Wang C, Zhang J, Fok KL, Tsang LL, Ye M, Liu J, Li F, Zhao AZ, Chan HC, Chen H. CD147 induces epithelial-to-mesenchymal transition by disassembling CAS/E-cadherin/β-catenin complex in human endometriosis. The American Journal of Pathology. PMID 29630856 DOI: 10.1016/j.ajpath.2018.03.004  0.68
2018 Sun H, Wang Y, Zhang J, Chen Y, Liu Y, Lin Z, Liu M, Sheng K, Liao H, Tsang KS, Zhang X, Jiang X, Xu W, Mao M, Chan HC. CFTR mutation enhances Dishevelled degradation and results in impairment of Wnt-dependent hematopoiesis. Cell Death & Disease. 9: 275. PMID 29449653 DOI: 10.1038/s41419-018-0311-9  0.68
2018 Zhang J, Wang Y, Jiang X, Chan HC. Cystic fibrosis transmembrane conductance regulator-emerging regulator of cancer. Cellular and Molecular Life Sciences : Cmls. PMID 29411041 DOI: 10.1007/s00018-018-2755-6  0.68
2018 Li X, Fok KL, Guo J, Wang Y, Liu Z, Chen Z, Wang C, Ruan YC, Yu SS, Zhao H, Wu J, Jiang X, Chan HC. Retinoic acid promotes stem cell differentiation and embryonic development by transcriptionally activating CFTR. Biochimica Et Biophysica Acta. PMID 29326073 DOI: 10.1016/j.bbamcr.2018.01.005  0.68
2017 Diao R, Wang T, Fok KL, Li X, Ruan Y, Yu MK, Cheng Y, Chen Y, Chen H, Mou L, Cai X, Wang Y, Cai Z, Zeng X, Chan HC. CCR6 is required for ligand-induced CatSper activation in human sperm. Oncotarget. 8: 91445-91458. PMID 29207656 DOI: 10.18632/oncotarget.20651  0.68
2017 Huang WQ, Guo JH, Yuan C, Cui YG, Diao FY, Yu MK, Liu JY, Ruan YC, Chan HC. Abnormal CFTR Affects Glucagon Production by Islet α Cells in Cystic Fibrosis and Polycystic Ovarian Syndrome. Frontiers in Physiology. 8: 835. PMID 29204121 DOI: 10.3389/fphys.2017.00835  0.4
2017 Huang WQ, Guo JH, Zhang XH, Yu MK, Chung YW, Ruan YC, Chan HC. Glucose-Sensitive CFTR Suppresses Glucagon Secretion by Potentiating KATP Channels in Pancreatic Islet α Cells. Endocrinology. 158: 3188-3199. PMID 28977595 DOI: 10.1210/en.2017-00282  0.4
2017 Fok KL, Bose R, Sheng K, Chang CW, Katz-Egorov M, Culty M, Su S, Yang M, Ruan YC, Chan HC, Iavarone A, Lasorella A, Cencic R, Pelletier J, Nagano M, et al. Huwe1 Regulates the Establishment and Maintenance of Spermatogonia by Suppressing DNA Damage Response. Endocrinology. PMID 28938460 DOI: 10.1210/en.2017-00396  0.48
2017 Chen JJ, Wang Y, Meng X, Ruan YC, Zou F, Chan HC. MRP4 regulates ENaC-dependent CREB/COX-2/PGE2 signaling during embryo implantation. Oncotarget. PMID 28775242 DOI: 10.18632/oncotarget.19676  0.68
2017 Zhang JT, Wang Y, Chen JJ, Zhang XH, Dong JD, Tsang LL, Huang XR, Cai Z, Lan HY, Jiang XH, Chan HC. Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis. Scientific Reports. 7: 5233. PMID 28701694 DOI: 10.1038/s41598-017-05435-5  0.68
2017 Chen K, Liu Q, Tsang LL, Ye Q, Chan HC, Sun Y, Jiang X. Human MSCs promotes colorectal cancer epithelial-mesenchymal transition and progression via CCL5/β-catenin/Slug pathway. Cell Death & Disease. 8: e2819. PMID 28542126 DOI: 10.1038/cddis.2017.138  0.68
2017 Huang W, Jin A, Zhang J, Wang C, Tsang LL, Cai Z, Zhou X, Chen H, Chan HC. Upregulation of CFTR in patients with endometriosis and its involvement in NFκB-uPAR dependent cell migration. Oncotarget. PMID 28415617 DOI: 10.18632/oncotarget.16441  0.68
2017 Chen H, Chan HC. Amplification of FSH signaling by CFTR and nuclear soluble adenylyl cyclase in the ovary. Clinical and Experimental Pharmacology & Physiology. PMID 28345252 DOI: 10.1111/1440-1681.12756  0.4
2017 Chen R, Lee WY, Zhang XH, Zhang JT, Lin S, Xu LL, Huang B, Yang FY, Liu HL, Wang B, Tsang LL, Willaime-Morawek S, Li G, Chan HC, Jiang X. Epigenetic Modification of the CCL5/CCR1/ERK Axis Enhances Glioma Targeting in Dedifferentiation-Reprogrammed BMSCs. Stem Cell Reports. PMID 28216148 DOI: 10.1016/j.stemcr.2017.01.016  0.68
2016 Wang C, Fok KL, Cai Z, Chen H, Chan HC. CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways. Oncotarget. PMID 27902973 DOI: 10.18632/oncotarget.13624  0.48
2016 Tu Z, Chen Q, Zhang JT, Jiang X, Xia Y, Chan HC. CFTR is a potential marker for nasopharyngeal carcinoma prognosis and metastasis. Oncotarget. PMID 27769067 DOI: 10.18632/oncotarget.12762  0.68
2016 Liu K, Zhang X, Zhang JT, Tsang LL, Jiang X, Chan HC. Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis. Oncotarget. PMID 27588407 DOI: 10.18632/oncotarget.11747  0.68
2016 Zhang Y, Xu J, Ruan YC, Yu MK, O'Laughlin M, Wise H, Chen D, Tian L, Shi D, Wang J, Chen S, Feng JQ, Chow DH, Xie X, Zheng L, ... ... Chan HC, et al. Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats. Nature Medicine. PMID 27571347 DOI: 10.1038/Nm.4162  0.4
2016 Lu YC, Yang J, Fok KL, Ye YH, Jin L, Chen ZY, Zhang XM, Huang HF, Chan HC. Involvement of Cl(-)/HCO3(-) exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage. Scientific Reports. 6: 28402. PMID 27346053 DOI: 10.1038/srep28402  0.48
2016 Zhang JT, Weng Z, Tsang KS, Tsang LL, Chan HC, Jiang XH. Correction: MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells. Plos One. 11: e0154068. PMID 27077735 DOI: 10.1371/journal.pone.0154068  0.44
2016 Siu GK, Zhou F, Yu MK, Zhang L, Wang T, Liang Y, Chen Y, Chan HC, Yu S. Hepatitis C virus NS5A protein cooperates with phosphatidylinositol 4-kinase IIIα to induce mitochondrial fragmentation. Scientific Reports. 6: 23464. PMID 27010100 DOI: 10.1038/srep23464  0.36
2016 Zhang JT, Weng ZH, Tsang KS, Tsang LL, Chan HC, Jiang XH. MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells. Plos One. 11: e0148062. PMID 26815535 DOI: 10.1371/journal.pone.0148062  0.44
2016 Ke LY, Chan HC, Chen CC, Lu X, Marathe GK, Chu CS, Chan HC, Wang CY, Tung YC, McIntyre TM, Yen JH, Chen CH. Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein. Journal of Medicinal Chemistry. PMID 26766134 DOI: 10.1021/acs.jmedchem.5b01534  0.32
2015 Dong ZW, Chen J, Ruan YC, Zhou T, Chen Y, Chen Y, Tsang LL, Chan HC, Peng YZ. CFTR-regulated MAPK/NF-κB signaling in pulmonary inflammation in thermal inhalation injury. Scientific Reports. 5: 15946. PMID 26515683 DOI: 10.1038/srep15946  0.32
2015 Li F, Chan HC, Liu S, Jia H, Li H, Hu Y, Wang Z, Huang W. Carbon monoxide poisoning as a cause of death in Wuhan, China: A retrospective six-year epidemiological study (2009-2014). Forensic Science International. 253: 112-118. PMID 26115227 DOI: 10.1016/j.forsciint.2015.06.007  0.32
2015 Wang C, Jin A, Huang W, Tsang LL, Cai Z, Zhou X, Chen H, Chan HC. Up-regulation of Bcl-2 by CD147 Through ERK Activation Results in Abnormal Cell Survival in Human Endometriosis. The Journal of Clinical Endocrinology and Metabolism. 100: E955-63. PMID 25996258 DOI: 10.1210/jc.2015-1431  0.32
2015 Chang KC, Lee AS, Chen WY, Lin YN, Hsu JF, Chan HC, Chang CM, Chang SS, Pan CC, Sawamura T, Chang CT, Su MJ, Chen CH. Increased LDL electronegativity in chronic kidney disease disrupts calcium homeostasis resulting in cardiac dysfunction. Journal of Molecular and Cellular Cardiology. 84: 36-44. PMID 25871829 DOI: 10.1016/j.yjmcc.2015.03.016  0.4
2015 Ma R, Wang Y, Yan L, Ma L, Wang Z, Chan HC, Chiu SK, Chen X, Zhu G. Efficient co-delivery of a Pt(IV) prodrug and a p53 activator to enhance the anticancer activity of cisplatin. Chemical Communications (Cambridge, England). 51: 7859-62. PMID 25854514 DOI: 10.1039/C4Cc09879J  0.32
2015 Wang F, Pan J, Liu Y, Meng Q, Lv P, Qu F, Ding GL, Klausen C, Leung PC, Chan HC, Yao W, Zhou CY, Shi B, Zhang J, Sheng J, et al. Alternative splicing of the androgen receptor in polycystic ovary syndrome. Proceedings of the National Academy of Sciences of the United States of America. 112: 4743-8. PMID 25825716 DOI: 10.1073/pnas.1418216112  0.32
2015 Chen CC, Huang JW, Zhao P, Ko TP, Huang CH, Chan HC, Huang Z, Liu W, Cheng YS, Liu JR, Guo RT. Structural analyses and yeast production of the β-1,3-1,4-glucanase catalytic module encoded by the licB gene of Clostridium thermocellum. Enzyme and Microbial Technology. 71: 1-7. PMID 25765303 DOI: 10.1016/j.enzmictec.2015.01.002  0.36
2015 Li J, Zhang JT, Jiang X, Shi X, Shen J, Feng F, Chen J, Liu G, He P, Jiang J, Tsang LL, Wang Y, Rosell R, Jiang L, He J, ... Chan HC, et al. The cystic fibrosis transmembrane conductance regulator as a biomarker in non-small cell lung cancer. International Journal of Oncology. 46: 2107-15. PMID 25760446 DOI: 10.3892/ijo.2015.2921  0.32
2015 Liu XM, Chan HC, Ding GL, Cai J, Song Y, Wang TT, Zhang D, Chen H, Yu MK, Wu YT, Qu F, Liu Y, Lu YC, Adashi EY, Sheng JZ, et al. FSH regulates fat accumulation and redistribution in aging through the Gαi/Ca(2+)/CREB pathway. Aging Cell. 14: 409-20. PMID 25754247 DOI: 10.1111/acel.12331  0.32
2015 Chen H, Guo JH, Zhang XH, Chan HC. Defective CFTR-regulated granulosa cell proliferation in polycystic ovarian syndrome. Reproduction (Cambridge, England). 149: 393-401. PMID 25646509 DOI: 10.1530/REP-14-0368  0.4
2015 Ma L, Ma R, Wang Y, Zhu X, Zhang J, Chan HC, Chen X, Zhang W, Chiu SK, Zhu G. Chalcoplatin, a dual-targeting and p53 activator-containing anticancer platinum(IV) prodrug with unique mode of action. Chemical Communications (Cambridge, England). 51: 6301-4. PMID 25644651 DOI: 10.1039/C4Cc10409A  0.32
2015 Dong J, Jiang X, Zhang X, Liu KS, Zhang J, Chen J, Yu MK, Tsang LL, Chung YW, Wang Y, Zhou WL, Chan HC. Dynamically Regulated CFTR Expression and Its Functional Role in Cutaneous Wound Healing. Journal of Cellular Physiology. 230: 2049-58. PMID 25641604 DOI: 10.1002/jcp.24931  0.32
2015 Xie C, Sun X, Chen J, Ng CF, Lau KM, Cai Z, Jiang X, Chan HC. Down-regulated CFTR During Aging Contributes to Benign Prostatic Hyperplasia. Journal of Cellular Physiology. 230: 1906-15. PMID 25546515 DOI: 10.1002/jcp.24921  0.32
2014 Feng X, Hu Y, Zheng Y, Zhu W, Li K, Huang CH, Ko TP, Ren F, Chan HC, Nega M, Bogue S, López D, Kolter R, Götz F, Guo RT, et al. Structural and functional analysis of Bacillus subtilis YisP reveals a role of its product in biofilm production. Chemistry & Biology. 21: 1557-63. PMID 25308276 DOI: 10.1016/J.Chembiol.2014.08.018  0.36
2014 Hu J, Chu Z, Han J, Zhang Q, Zhang D, Dang Y, Ren J, Chan HC, Zhang J, Huang Y. Phosphorylation-dependent mitochondrial translocation of MAP4 is an early step in hypoxia-induced apoptosis in cardiomyocytes. Cell Death & Disease. 5: e1424. PMID 25232678 DOI: 10.1038/cddis.2014.369  0.68
2014 Sun X, Ruan YC, Guo J, Chen H, Tsang LL, Zhang X, Jiang X, Chan HC. Regulation of miR-101/miR-199a-3p by the epithelial sodium channel during embryo implantation: involvement of CREB phosphorylation. Reproduction (Cambridge, England). 148: 559-68. PMID 25187622 DOI: 10.1530/REP-14-0386  0.32
2014 Diao R, Fok KL, Chen H, Yu MK, Duan Y, Chung CM, Li Z, Wu H, Li Z, Zhang H, Ji Z, Zhen W, Ng CF, Gui Y, Cai Z, ... Chan HC, et al. Deficient human β-defensin 1 underlies male infertility associated with poor sperm motility and genital tract infection. Science Translational Medicine. 6: 249ra108. PMID 25122636 DOI: 10.1126/scitranslmed.3009071  0.32
2014 Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S. CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation through the ZONAB pathway. Journal of Cell Science. 127: 4396-408. PMID 25107366 DOI: 10.1242/jcs.148098  0.68
2014 Yang Y, Ko TP, Liu L, Li J, Huang CH, Chan HC, Ren F, Jia D, Wang AH, Guo RT, Chen J, Du G. Structural insights into enzymatic degradation of oxidized polyvinyl alcohol. Chembiochem : a European Journal of Chemical Biology. 15: 1882-6. PMID 25044912 DOI: 10.1002/cbic.201402166  0.36
2014 Guo JH, Chen H, Ruan YC, Zhang XL, Zhang XH, Fok KL, Tsang LL, Yu MK, Huang WQ, Sun X, Chung YW, Jiang X, Sohma Y, Chan HC. Glucose-induced electrical activities and insulin secretion in pancreatic islet β-cells are modulated by CFTR. Nature Communications. 5: 4420. PMID 25025956 DOI: 10.1038/ncomms5420  0.32
2014 Wang S, Nie Y, Yan X, Ko TP, Huang CH, Chan HC, Guo RT, Xiao R. Crystallization and preliminary X-ray diffraction analysis of (R)-carbonyl reductase from Candida parapsilosis. Acta Crystallographica. Section F, Structural Biology Communications. 70: 800-2. PMID 24915097 DOI: 10.1107/S2053230X1400908X  0.36
2014 Chan HC, Jiang X, Ruan YC. Emerging role of cystic fibrosis transmembrane conductance regulator as an epigenetic regulator: linking environmental cues to microRNAs. Clinical and Experimental Pharmacology & Physiology. 41: 615-22. PMID 24909068 DOI: 10.1111/1440-1681.12271  0.68
2014 Sun T, Guo J, Chen H, Zhang J, Zhang X, Jiang X, Wang F, Xu Z, Huang X, Sha J, Chan HC. Maternal caffeine exposure impairs insulin secretion by pancreatic β-cells and increases the risk of type II diabetes mellitus in offspring. Cell Biology International. 38: 1183-93. PMID 24890676 DOI: 10.1002/Cbin.10321  0.68
2014 Wang S, Nie Y, Xu Y, Zhang R, Ko TP, Huang CH, Chan HC, Guo RT, Xiao R. Unconserved substrate-binding sites direct the stereoselectivity of medium-chain alcohol dehydrogenase. Chemical Communications (Cambridge, England). 50: 7770-2. PMID 24834985 DOI: 10.1039/c4cc01752h  0.36
2014 Shang N, Li Q, Ko TP, Chan HC, Li J, Zheng Y, Huang CH, Ren F, Chen CC, Zhu Z, Galizzi M, Li ZH, Rodrigues-Poveda CA, Gonzalez-Pacanowska D, Veiga-Santos P, et al. Squalene synthase as a target for Chagas disease therapeutics. Plos Pathogens. 10: e1004114. PMID 24789335 DOI: 10.1371/Journal.Ppat.1004114  0.36
2014 Lee AS, Chen WY, Chan HC, Hsu JF, Shen MY, Chang CM, Bair H, Su MJ, Chang KC, Chen CH. Gender disparity in LDL-induced cardiovascular damage and the protective role of estrogens against electronegative LDL. Cardiovascular Diabetology. 13: 64. PMID 24666525 DOI: 10.1186/1475-2840-13-64  0.4
2014 Jin A, Chen H, Wang C, Tsang LL, Jiang X, Cai Z, Chan HC, Zhou X. Elevated expression of CD147 in patients with endometriosis and its role in regulating apoptosis and migration of human endometrial cells. Fertility and Sterility. 101: 1681-7.e1. PMID 24661733 DOI: 10.1016/j.fertnstert.2014.02.007  0.32
2014 Fok KL, Chen H, Ruan YC, Chan HC. Novel regulators of spermatogenesis. Seminars in Cell & Developmental Biology. 29: 31-42. PMID 24594193 DOI: 10.1016/j.semcdb.2014.02.008  0.48
2014 Ruan YC, Chen H, Chan HC. Ion channels in the endometrium: regulation of endometrial receptivity and embryo implantation. Human Reproduction Update. 20: 517-29. PMID 24591147 DOI: 10.1093/humupd/dmu006  0.4
2014 Chan HC, Feng X, Ko TP, Huang CH, Hu Y, Zheng Y, Bogue S, Nakano C, Hoshino T, Zhang L, Lv P, Liu W, Crick DC, Liang PH, Wang AH, et al. Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis. Journal of the American Chemical Society. 136: 2892-6. PMID 24475925 DOI: 10.1021/Ja413127V  0.36
2014 Xu J, Ren F, Huang CH, Zheng Y, Zhen J, Sun H, Ko TP, He M, Chen CC, Chan HC, Guo RT, Song H, Ma Y. Functional and structural studies of pullulanase from Anoxybacillus sp. LM18-11. Proteins. 82: 1685-93. PMID 24375572 DOI: 10.1002/prot.24498  0.36
2014 Sun TT, Wang Y, Cheng H, Xiao HZ, Xiang JJ, Zhang JT, Yu SB, Martin TA, Ye L, Tsang LL, Jiang WG, Xiaohua J, Chan HC. Disrupted interaction between CFTR and AF-6/afadin aggravates malignant phenotypes of colon cancer. Biochimica Et Biophysica Acta. 1843: 618-28. PMID 24373847 DOI: 10.1016/j.bbamcr.2013.12.013  0.32
2013 Guo G, Sun X, Chen C, Wu S, Huang P, Li Z, Dean M, Huang Y, Jia W, Zhou Q, Tang A, Yang Z, Li X, Song P, Zhao X, ... ... Chan HC, et al. Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nature Genetics. 45: 1459-63. PMID 24121792 DOI: 10.1038/ng.2798  0.32
2013 Luo W, Huang JW, Huang CH, Huang TY, Chan HC, Liu JR, Guo RT, Chen CC. Preliminary X-ray diffraction analysis of thermostable β-1,4-mannanase from Aspergillus niger BK01. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1100-2. PMID 24100557 DOI: 10.1107/S1744309113023348  0.36
2013 Diao R, Fok KL, Zhao L, Chen H, Tang H, Chen J, Zheng A, Zhang X, Gui Y, Chan HC, Cai Z. Decreased expression of cystic fibrosis transmembrane conductance regulator impairs sperm quality in aged men. Reproduction (Cambridge, England). 146: 637-45. PMID 24077955 DOI: 10.1530/REP-13-0146  0.48
2013 Zhang JT, Jiang XH, Xie C, Cheng H, Da Dong J, Wang Y, Fok KL, Zhang XH, Sun TT, Tsang LL, Chen H, Sun XJ, Chung YW, Cai ZM, Jiang WG, ... Chan HC, et al. Downregulation of CFTR promotes epithelial-to-mesenchymal transition and is associated with poor prognosis of breast cancer. Biochimica Et Biophysica Acta. 1833: 2961-9. PMID 23916755 DOI: 10.1016/j.bbamcr.2013.07.021  0.32
2013 Jiang T, Chan HC, Huang CH, Ko TP, Huang TY, Liu JR, Guo RT. Substrate binding to a GH131 β-glucanase catalytic domain from Podospora anserina. Biochemical and Biophysical Research Communications. 438: 193-7. PMID 23880343 DOI: 10.1016/j.bbrc.2013.07.051  0.36
2013 Han X, Gao J, Shang N, Huang CH, Ko TP, Chen CC, Chan HC, Cheng YS, Zhu Z, Wiegel J, Luo W, Guo RT, Ma Y. Structural and functional analyses of catalytic domain of GH10 xylanase from Thermoanaerobacterium saccharolyticum JW/SL-YS485. Proteins. 81: 1256-65. PMID 23508990 DOI: 10.1002/prot.24286  0.36
2013 Ren F, Feng X, Ko TP, Huang CH, Hu Y, Chan HC, Liu YL, Wang K, Chen CC, Pang X, He M, Li Y, Oldfield E, Guo RT. Insights into TIM-barrel prenyl transferase mechanisms: crystal structures of PcrB from Bacillus subtilis and Staphylococcus aureus. Chembiochem : a European Journal of Chemical Biology. 14: 195-9. PMID 23322418 DOI: 10.1002/Cbic.201200748  0.36
2013 Chen H, Kui C, Chan HC. Ca(2+) mobilization in cumulus cells: role in oocyte maturation and acrosome reaction. Cell Calcium. 53: 68-75. PMID 23218669 DOI: 10.1016/j.ceca.2012.11.007  0.4
2013 Xie C, Jiang XH, Zhang JT, Sun TT, Dong JD, Sanders AJ, Diao RY, Wang Y, Fok KL, Tsang LL, Yu MK, Zhang XH, Chung YW, Ye L, Zhao MY, ... ... Chan HC, et al. CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer. Oncogene. 32: 2282-91, 2291.e1-7. PMID 22797075 DOI: 10.1038/onc.2012.251  0.32
2012 Chan HC, Chen H, Ruan Y, Sun T. Physiology and pathophysiology of the epithelial barrier of the female reproductive tract: role of ion channels. Advances in Experimental Medicine and Biology. 763: 193-217. PMID 23397626 DOI: 10.1007/978-1-4614-4711-5_10  0.4
2012 Zhang XH, Ma ZG, Rowlands DK, Gou YL, Fok KL, Wong HY, Yu MK, Tsang LL, Mu L, Chen L, Yung WH, Chung YW, Zhang BL, Zhao H, Chan HC. Flavonoid Myricetin Modulates GABA(A) Receptor Activity through Activation of Ca(2+) Channels and CaMK-II Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2012: 758097. PMID 23258999 DOI: 10.1155/2012/758097  0.32
2012 Hu JC, Chan HC, Simmer SG, Seymen F, Richardson AS, Hu Y, Milkovich RN, Estrella NM, Yildirim M, Bayram M, Chen CF, Simmer JP. Amelogenesis imperfecta in two families with defined AMELX deletions in ARHGAP6. Plos One. 7: e52052. PMID 23251683 DOI: 10.1371/journal.pone.0052052  0.4
2012 Chen H, Lam Fok K, Jiang X, Chan HC. New insights into germ cell migration and survival/apoptosis in spermatogenesis: Lessons from CD147. Spermatogenesis. 2: 264-272. PMID 23248767 DOI: 10.4161/spmg.22014  0.68
2012 Wang SK, Chan HC, Makovey I, Simmer JP, Hu JC. Novel PAX9 and COL1A2 missense mutations causing tooth agenesis and OI/DGI without skeletal abnormalities. Plos One. 7: e51533. PMID 23227268 DOI: 10.1371/journal.pone.0051533  0.4
2012 Jiang X, Zhang JT, Chan HC. Ion channels/transporters as epigenetic regulators? -a microRNA perspective. Science China. Life Sciences. 55: 753-60. PMID 23015123 DOI: 10.1007/s11427-012-4369-9  0.68
2012 Huang CH, Sun Y, Ko TP, Chen CC, Zheng Y, Chan HC, Pang X, Wiegel J, Shao W, Guo RT. The substrate/product-binding modes of a novel GH120 β-xylosidase (XylC) from Thermoanaerobacterium saccharolyticum JW/SL-YS485. The Biochemical Journal. 448: 401-7. PMID 22992047 DOI: 10.1042/BJ20121359  0.36
2012 Chen J, Fok KL, Chen H, Zhang XH, Xu WM, Chan HC. Cryptorchidism-induced CFTR down-regulation results in disruption of testicular tight junctions through up-regulation of NF-κB/COX-2/PGE2. Human Reproduction (Oxford, England). 27: 2585-97. PMID 22777528 DOI: 10.1093/humrep/des254  0.48
2012 Ruan YC, Guo JH, Liu X, Zhang R, Tsang LL, Dong JD, Chen H, Yu MK, Jiang X, Zhang XH, Fok KL, Chung YW, Huang H, Zhou WL, Chan HC. Activation of the epithelial Na+ channel triggers prostaglandin Eâ‚‚ release and production required for embryo implantation. Nature Medicine. 18: 1112-7. PMID 22729284 DOI: 10.1038/nm.2771  0.32
2012 Chen H, Ruan YC, Xu WM, Chen J, Chan HC. Regulation of male fertility by CFTR and implications in male infertility. Human Reproduction Update. 18: 703-13. PMID 22709980 DOI: 10.1093/humupd/dms027  0.4
2012 Lu YC, Chen H, Fok KL, Tsang LL, Yu MK, Zhang XH, Chen J, Jiang X, Chung YW, Ma AC, Leung AY, Huang HF, Chan HC. CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell Research. 22: 1453-66. PMID 22664907 DOI: 10.1038/cr.2012.88  0.68
2012 Wu W, Song W, Li S, Ouyang S, Fok KL, Diao R, Miao S, Chan HC, Wang L. Regulation of apoptosis by Bat3-enhanced YWK-II/APLP2 protein stability. Journal of Cell Science. 125: 4219-29. PMID 22641691 DOI: 10.1242/jcs.086553  0.48
2012 Tang XX, Fok KL, Chen H, Chan KS, Tsang LL, Rowlands DK, Zhang XH, Dong JD, Ruan YC, Jiang X, Yu SS, Chung YW, Chan HC. Lymphocyte CFTR promotes epithelial bicarbonate secretion for bacterial killing. Journal of Cellular Physiology. 227: 3887-94. PMID 22552906 DOI: 10.1002/jcp.24101  0.68
2012 Chen H, Fok KL, Jiang X, Jiang J, Chen Z, Gui Y, Chan HC, Cai Z. CD147 regulates apoptosis in mouse spermatocytes but not spermatogonia. Human Reproduction (Oxford, England). 27: 1568-76. PMID 22451502 DOI: 10.1093/humrep/des050  0.68
2012 Ren F, Ko TP, Feng X, Huang CH, Chan HC, Hu Y, Wang K, Ma Y, Liang PH, Wang AH, Oldfield E, Guo RT. Insights into the mechanism of the antibiotic-synthesizing enzyme MoeO5 from crystal structures of different complexes. Angewandte Chemie (International Ed. in English). 51: 4157-60. PMID 22431288 DOI: 10.1002/Anie.201108002  0.36
2012 Chan HC, Zhu Y, Hu Y, Ko TP, Huang CH, Ren F, Chen CC, Ma Y, Guo RT, Sun Y. Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. Protein & Cell. 3: 123-31. PMID 22426981 DOI: 10.1007/s13238-012-2026-5  0.36
2012 Fu J, Wang Y, Fok KL, Yang D, Qiu Y, Chan HC, Koide SS, Miao S, Wang L. Anti-ACTL7a antibodies: a cause of infertility. Fertility and Sterility. 97: 1226-33.e1-8. PMID 22386842 DOI: 10.1016/j.fertnstert.2012.02.023  0.68
2012 Peng X, Wu Z, Yu L, Li J, Xu W, Chan HC, Zhang Y, Hu L. Overexpression of cystic fibrosis transmembrane conductance regulator (CFTR) is associated with human cervical cancer malignancy, progression and prognosis. Gynecologic Oncology. 125: 470-6. PMID 22366595 DOI: 10.1016/j.ygyno.2012.02.015  0.36
2012 Jiang X, Chan HC. Magnetic nanoparticles for treatment of gastric cancer. Journal of Gastroenterology and Hepatology. 27: 191-3. PMID 22260281 DOI: 10.1111/j.1440-1746.2011.07031.x  0.68
2012 Chen H, Guo JH, Lu YC, Ding GL, Yu MK, Tsang LL, Fok KL, Liu XM, Zhang XH, Chung YW, Huang P, Huang H, Chan HC. Impaired CFTR-dependent amplification of FSH-stimulated estrogen production in cystic fibrosis and PCOS. The Journal of Clinical Endocrinology and Metabolism. 97: 923-32. PMID 22170719 DOI: 10.1210/jc.2011-1363  0.48
2012 Rowlands DK, Cui YG, So SC, Tsang LL, Chung YW, Chan HC. Bak Foong Pills induce an analgesic effect by inhibiting nociception via the somatostatin pathway in mice. Cell Biology International. 36: 63-9. PMID 21980955 DOI: 10.1042/CBI20110015  0.4
2012 Chen J, Jiang XH, Chen H, Guo JH, Tsang LL, Yu MK, Xu WM, Chan HC. CFTR negatively regulates cyclooxygenase-2-PGE(2) positive feedback loop in inflammation. Journal of Cellular Physiology. 227: 2759-66. PMID 21913191 DOI: 10.1002/jcp.23020  0.4
2012 Zhang J, Dong J, Gu H, Yu S, Zhang X, Gou Y, Xu W, Burd A, Huang L, Miyado K, Huang Y, Chan HC. CD9 is critical for cutaneous wound healing through JNK signaling. The Journal of Investigative Dermatology. 132: 226-36. PMID 21881583 DOI: 10.1038/jid.2011.268  0.68
2011 Chan HC, Estrella NM, Milkovich RN, Kim JW, Simmer JP, Hu JC. Target gene analyses of 39 amelogenesis imperfecta kindreds. European Journal of Oral Sciences. 119: 311-23. PMID 22243262 DOI: 10.1111/j.1600-0722.2011.00857.x  0.4
2011 Wang SK, Chan HC, Rajderkar S, Milkovich RN, Uston KA, Kim JW, Simmer JP, Hu JC. Enamel malformations associated with a defined dentin sialophosphoprotein mutation in two families. European Journal of Oral Sciences. 119: 158-67. PMID 22243242 DOI: 10.1111/j.1600-0722.2011.00874.x  0.4
2011 Liu Y, Jiang X, Zhang X, Chen R, Sun T, Fok KL, Dong J, Tsang LL, Yi S, Ruan Y, Guo J, Yu MK, Tian Y, Chung YW, Yang M, ... ... Chan HC, et al. Dedifferentiation-reprogrammed mesenchymal stem cells with improved therapeutic potential. Stem Cells (Dayton, Ohio). 29: 2077-89. PMID 22052697 DOI: 10.1002/stem.764  0.68
2011 Ruan YC, Zhou W, Chan HC. Regulation of smooth muscle contraction by the epithelium: role of prostaglandins. Physiology (Bethesda, Md.). 26: 156-70. PMID 21670162 DOI: 10.1152/physiol.00036.2010  0.32
2011 Xu WM, Chen J, Chen H, Diao RY, Fok KL, Dong JD, Sun TT, Chen WY, Yu MK, Zhang XH, Tsang LL, Lau A, Shi QX, Shi QH, Huang PB, ... Chan HC, et al. Defective CFTR-dependent CREB activation results in impaired spermatogenesis and azoospermia. Plos One. 6: e19120. PMID 21625623 DOI: 10.1371/journal.pone.0019120  0.48
2011 Yang JZ, Jiang X, Dong J, Guo J, Chen H, Tsang LL, Chung YW, Zhang X, Chan HC. Abnormally enhanced cystic fibrosis transmembrane conductance regulator-mediated apoptosis in endometrial cells contributes to impaired embryo implantation in controlled ovarian hyperstimulation. Fertility and Sterility. 95: 2100-6, 2106.e1-2. PMID 21420082 DOI: 10.1016/j.fertnstert.2011.02.036  0.68
2011 Yu L, Jiang XH, Zhou Z, Tsang LL, Yu MK, Chung YW, Zhang XH, Wang AM, Tang H, Chan HC. A protective mechanism against antibiotic-induced ototoxicity: role of prestin. Plos One. 6: e17322. PMID 21364896 DOI: 10.1371/journal.pone.0017322  0.4
2011 Chen H, Fok KL, Yu S, Jiang J, Chen Z, Gui Y, Cai Z, Chan HC. CD147 is required for matrix metalloproteinases-2 production and germ cell migration during spermatogenesis. Molecular Human Reproduction. 17: 405-14. PMID 21343160 DOI: 10.1093/molehr/gar013  0.48
2010 Xie C, Tang X, Xu W, Diao R, Cai Z, Chan HC. A host defense mechanism involving CFTR-mediated bicarbonate secretion in bacterial prostatitis. Plos One. 5: e15255. PMID 21151921 DOI: 10.1371/journal.pone.0015255  0.4
2010 Yu L, Tang H, Jiang XH, Tsang LL, Chung YW, Chan HC. Involvement of calpain-I and microRNA34 in kanamycin-induced apoptosis of inner ear cells. Cell Biology International. 34: 1219-25. PMID 21067520 DOI: 10.1042/CBI20100515  0.4
2010 He Q, Chen H, Wong CH, Tsang LL, Chan HC. Regulatory mechanism underlying cyclic changes in mouse uterine bicarbonate secretion: role of estrogen. Reproduction (Cambridge, England). 140: 903-10. PMID 20876742 DOI: 10.1530/REP-10-0178  0.4
2010 Tang XX, Chen H, Yu S, Zhang L, Caplan MJ, Chan HC. Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK). Plos One. 5: e12343. PMID 20808811 DOI: 10.1371/journal.pone.0012343  0.4
2010 Chen MH, Chen H, Zhou Z, Ruan YC, Wong HY, Lu YC, Guo JH, Chung YW, Huang PB, Huang HF, Zhou WL, Chan HC. Involvement of CFTR in oviductal HCO3- secretion and its effect on soluble adenylate cyclase-dependent early embryo development. Human Reproduction (Oxford, England). 25: 1744-54. PMID 20406739 DOI: 10.1093/humrep/deq094  0.32
2010 Zhang WK, Wang D, Duan Y, Loy MM, Chan HC, Huang P. Mechanosensitive gating of CFTR. Nature Cell Biology. 12: 507-12. PMID 20400957 DOI: 10.1038/ncb2053  0.32
2010 Ajonuma LC, Fok KL, Ho LS, Chan PK, Chow PH, Tsang LL, Wong CH, Chen J, Li S, Rowlands DK, Chung YW, Chan HC. CFTR is required for cellular entry and internalization of Chlamydia trachomatis. Cell Biology International. 34: 593-600. PMID 20178459 DOI: 10.1042/Cbi20090227  0.32
2010 Xu W, Zhang X, Chen W, Fok KL, Rowlands DK, Chui YL, Chan HC. Immunization with Bin1b decreases sperm motility with compromised fertility in rats. Fertility and Sterility. 93: 952-958.e1. PMID 19135192 DOI: 10.1016/J.Fertnstert.2008.10.066  0.48
2009 Jin JY, Chen WY, Zhou CX, Chen ZH, Yu-Ying Y, Ni Y, Chan HC, Shi QX. Activation of GABAA receptor/Cl- channel and capacitation in rat spermatozoa: HCO3- and Cl- are essential. Systems Biology in Reproductive Medicine. 55: 97-108. PMID 19462289 DOI: 10.1080/19396360802626648  0.4
2009 Chen J, Ng CP, Tsang LL, Ho LS, Xu PH, Rowlands DK, Gao JY, Chung YW, Li TY, Chan HC. Altered expression of inflammatory cytokine receptors in response to LPS challenge through interaction between intestinal epithelial cells and lymphocytes of Peyer's patch. Cell Biology International. 33: 369-75. PMID 19385035 DOI: 10.1016/j.cellbi.2009.01.004  0.32
2009 Rowlands DK, Cui YG, Wong HY, Gou YL, Chan HC. Traditional Chinese medicine Bak Foong Pills alters uterine quiescence - possible role in alleviation of dysmenorrhoeal symptoms. Cell Biology International. 33: 1207-11. PMID 19341810 DOI: 10.1016/j.cellbi.2009.03.003  0.36
2009 Bi Y, Xu WM, Wong HY, Zhu H, Zhou ZM, Chan HC, Sha JH. NYD-SP27, a novel intrinsic decapacitation factor in sperm. Asian Journal of Andrology. 11: 229-39. PMID 19252507 DOI: 10.1038/aja.2009.6  0.4
2009 Yin L, Chung CM, Huo R, Liu H, Zhou C, Xu W, Zhu H, Zhang J, Shi Q, Wong HY, Chen J, Lu Y, Bi Y, Zhao C, Du Y, ... ... Chan HC, et al. A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction. Cellular and Molecular Life Sciences : Cmls. 66: 900-8. PMID 19153666 DOI: 10.1007/s00018-009-8482-2  0.68
2009 Yin LL, Chung CM, Chen J, Fok KL, Ng CP, Jia RR, Ren X, Zhou J, Zhang T, Zhao XH, Lin M, Zhu H, Zhang XH, Tsang LL, Bi Y, ... ... Chan HC, et al. A suppressor of multiple extracellular matrix-degrading proteases and cancer metastasis. Journal of Cellular and Molecular Medicine. 13: 4034-41. PMID 19017363 DOI: 10.1111/J.1582-4934.2008.00576.X  0.48
2009 Chan HC, Ruan YC, He Q, Chen MH, Chen H, Xu WM, Chen WY, Xie C, Zhang XH, Zhou Z. The cystic fibrosis transmembrane conductance regulator in reproductive health and disease. The Journal of Physiology. 587: 2187-95. PMID 19015188 DOI: 10.1113/jphysiol.2008.164970  0.4
2009 Chen WY, Xu WM, Chen ZH, Ni Y, Yuan YY, Zhou SC, Zhou WW, Tsang LL, Chung YW, Höglund P, Chan HC, Shi QX. Cl- is required for HCO3- entry necessary for sperm capacitation in guinea pig: involvement of a Cl-/HCO3- exchanger (SLC26A3) and CFTR. Biology of Reproduction. 80: 115-23. PMID 18784352 DOI: 10.1095/biolreprod.108.068528  0.4
2008 Ajonuma LC, Chan PK, Ng EH, Fok KL, Wong CH, Tsang LL, Tang XX, Ho LS, Lau MC, Chung CM, He Q, Huang HY, Yang DZ, Rowlands DK, Chung YW, ... Chan HC, et al. Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection. The Journal of Obstetrics and Gynaecology Research. 34: 923-30. PMID 19012687 DOI: 10.1111/j.1447-0756.2008.00826.x  0.32
2008 Wang Y, Guan X, Fok KL, Li S, Zhang X, Miao S, Zong S, Koide SS, Chan HC, Wang L. A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis. Cellular and Molecular Life Sciences : Cmls. 65: 3822-9. PMID 18953687 DOI: 10.1007/s00018-008-8452-0  0.68
2008 Ajonuma LC, He Q, Sheung Chan PK, Yu Ng EH, Fok KL, Yan Wong CH, Tsang LL, Ho LS, Lau MC, Huang HY, Yang DZ, Rowlands DK, Tang XX, Zhang XH, Chung YW, ... Chan HC, et al. Involvement of cystic fibrosis transmembrane conductance regulator in infection-induced edema. Cell Biology International. 32: 801-6. PMID 18462959 DOI: 10.1016/j.cellbi.2008.03.010  0.32
2008 Liu B, Xie JX, Tsang LL, Rowlands DK, Ho LS, Gou YL, Chung YW, Chan HC. Bak Foong protects dopaminergic neurons against MPTP-induced neurotoxicity by its anti-apoptotic activity. Cell Biology International. 32: 86-92. PMID 17920944 DOI: 10.1016/j.cellbi.2007.08.016  0.32
2007 Zhang GH, Zhu JX, Xue H, Fan J, Chen X, Tsang LL, Chung YW, Xing Y, Chan HC. Dopamine stimulates Cl(-) absorption coupled with HCO(3)(-) secretion in rat late distal colon. European Journal of Pharmacology. 570: 188-95. PMID 17597606 DOI: 10.1016/j.ejphar.2007.05.038  0.4
2007 Xu WM, Shi QX, Chen WY, Zhou CX, Ni Y, Rowlands DK, Yi Liu G, Zhu H, Ma ZG, Wang XF, Chen ZH, Zhou SC, Dong HS, Zhang XH, Chung YW, ... ... Chan HC, et al. Cystic fibrosis transmembrane conductance regulator is vital to sperm fertilizing capacity and male fertility. Proceedings of the National Academy of Sciences of the United States of America. 104: 9816-21. PMID 17519339 DOI: 10.1073/Pnas.0609253104  0.4
2007 Yin X, Ouyang S, Xu W, Zhang X, Fok KL, Wong HY, Zhang J, Qiu X, Miao S, Chan HC, Wang L. YWK-II protein as a novel G(o)-coupled receptor for Müllerian inhibiting substance in cell survival. Journal of Cell Science. 120: 1521-8. PMID 17452623 DOI: 10.1242/jcs.001230  0.68
2007 Zhu JX, Yang N, Zhu H, Chung YW, Chan HC. Effect of NYD-SP27 down-regulation on ATP-induced Ca2+-dependent pancreatic duct anion secretion in cystic fibrosis cells. Cell Biology International. 31: 521-5. PMID 17196844 DOI: 10.1016/J.Cellbi.2006.11.021  0.32
2006 Ho LS, Tsang LL, Chung YW, Chan HC. Establishment of a mouse primary co-culture of endometrial epithelial cells and peripheral blood leukocytes: effect on epithelial barrier function and leukocyte survival. Cell Biology International. 30: 977-82. PMID 17011218 DOI: 10.1016/j.cellbi.2006.07.004  0.32
2006 Shu C, Li TY, Tsang LL, Fok KL, Lo PS, Zhu JX, Ho LS, Chung YW, Chan HC. Differentiation of adult rat bone marrow stem cells into epithelial progenitor cells in culture. Cell Biology International. 30: 823-8. PMID 16877014 DOI: 10.1016/j.cellbi.2006.06.004  0.32
2006 Chan HC, Shi QX, Zhou CX, Wang XF, Xu WM, Chen WY, Chen AJ, Ni Y, Yuan YY. Critical role of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Molecular and Cellular Endocrinology. 250: 106-13. PMID 16414184 DOI: 10.1016/j.mce.2005.12.032  0.4
2005 Zhao WC, Zhu JX, Zhang GH, Wong CH, Chung YW, Chan HC. Effect of sodium ferulate on human colonic anion secretion and the underlying signaling mechanism. Biological & Pharmaceutical Bulletin. 28: 1608-11. PMID 16141524 DOI: 10.1248/BPB.28.1608  0.36
2005 Yang JZ, Ajonuma LC, Rowlands DK, Tsang LL, Ho LS, Lam SY, Chen WY, Zhou CX, Chung YW, Cho CY, Tse JY, James AE, Chan HC. The role of inducible nitric oxide synthase in gamete interaction and fertilization: a comparative study on knockout mice of three NOS isoforms. Cell Biology International. 29: 785-91. PMID 16087361 DOI: 10.1016/j.cellbi.2005.05.005  0.32
2005 Ajonuma LC, Tsang LL, Zhang GH, Wong CH, Lau MC, Ho LS, Rowlands DK, Zhou CX, Ng CP, Chen J, Xu PH, Zhu JX, Chung YW, Chan HC. Estrogen-induced abnormally high cystic fibrosis transmembrane conductance regulator expression results in ovarian hyperstimulation syndrome. Molecular Endocrinology (Baltimore, Md.). 19: 3038-44. PMID 16051669 DOI: 10.1210/me.2005-0114  0.4
2005 Zhu JX, Zhang GH, Yang N, Rowlands DK, Wong HY, Tsang LL, Chung YW, Chan HC. Activation of apical CFTR and basolateral Ca(2+)-activated K+ channels by tetramethylpyrazine in Caco-2 cell line. European Journal of Pharmacology. 510: 187-95. PMID 15763242 DOI: 10.1016/j.ejphar.2005.01.026  0.4
2005 Ajonuma LC, Ng EH, Chow PH, Hung CY, Tsang LL, Cheung AN, Brito-Jones C, Lok IH, J Haines C, Chan HC. Increased cystic fibrosis transmembrane conductance regulator (CFTR) expression in the human hydrosalpinx. Human Reproduction (Oxford, England). 20: 1228-34. PMID 15705621 DOI: 10.1093/Humrep/Deh773  0.4
2004 Li TY, Shu C, Wong CH, Lo PS, Zhu H, Lau MC, Chan MY, Tsang LL, Gou YL, Chung YW, Chan HC. Plasticity of rat bone marrow-derived 5-hydroxytryptamine-sensitive neurons: dedifferentiation and redifferentiation. Cell Biology International. 28: 801-7. PMID 15563402 DOI: 10.1016/J.Cellbi.2004.07.010  0.32
2004 Tsang LL, Chan LN, Chan HC. Altered cyclic expression of epithelial Na+ channel subunits and cystic fibrosis transmembrane conductance regulator in mouse endometrium by a low sodium diet Cell Biology International. 28: 549-555. PMID 15261163 DOI: 10.1016/j.cellbi.2004.04.011  0.32
2004 Ning Y, Zhu JX, Chan HC. Regulation of ion transport by 5-hydroxytryptamine in rat colon. Clinical and Experimental Pharmacology & Physiology. 31: 424-8. PMID 15236628 DOI: 10.1111/j.1440-1681.2004.04015.x  0.32
2004 Yang JZ, Ajonuma LC, Tsang LL, Lam SY, Rowlands DK, Ho LS, Zhou CX, Chung YW, Chan HC. Differential expression and localization of CFTR and ENaC in mouse endometrium during pre-implantation. Cell Biology International. 28: 433-9. PMID 15223019 DOI: 10.1016/j.cellbi.2004.03.011  0.32
2004 Zhou CX, Zhang YL, Xiao L, Zheng M, Leung KM, Chan MY, Lo PS, Tsang LL, Wong HY, Ho LS, Chung YW, Chan HC. An epididymis-specific beta-defensin is important for the initiation of sperm maturation. Nature Cell Biology. 6: 458-64. PMID 15122269 DOI: 10.1038/ncb1127  0.4
2003 Ho AL, Gou YL, Rowlands DK, Chung YW, Chan HC. Effects of Bak Foong Pills and Menoease Pills on white blood cell distribution in old age female rats. Biological & Pharmaceutical Bulletin. 26: 1748-53. PMID 14646184 DOI: 10.1248/BPB.26.1748  0.36
2003 Tang N, Zhu JX, Zhao WC, Xing Y, Gou YL, Rowlands DK, Chung YW, Chan HC. Effect of Bak Foong pills on exocrine pancreatic-bile secretion. Biological & Pharmaceutical Bulletin. 26: 1384-7. PMID 14519940 DOI: 10.1248/BPB.26.1384  0.36
2003 Wang XF, Zhou CX, Shi QX, Yuan YY, Yu MK, Ajonuma LC, Ho LS, Lo PS, Tsang LL, Liu Y, Lam SY, Chan LN, Zhao WC, Chung YW, Chan HC. Involvement of CFTR in uterine bicarbonate secretion and the fertilizing capacity of sperm. Nature Cell Biology. 5: 902-6. PMID 14515130 DOI: 10.1038/ncb1047  0.32
2003 Yang JZ, Ho AL, Ajonuma LC, Lam SY, Tsang LL, Tang N, Rowlands DK, Gou YL, Chung YW, Chan HC. Differential effects of Matrigel and its components on functional activity of CFTR and ENaC in mouse endometrial epithelial cells. Cell Biology International. 27: 543-8. PMID 12842093 DOI: 10.1016/S1065-6995(03)00079-9  0.4
2003 Gou YL, Ho AL, Rowlands DK, Chung YW, Chan HC. Effects of Bak Foong Pill on blood coagulation and platelet aggregation. Biological & Pharmaceutical Bulletin. 26: 241-6. PMID 12576687 DOI: 10.1248/BPB.26.241  0.36
2003 Ajonuma LC, Chan LN, Ng EH, Chow PH, Kung LS, Cheung AN, Briton-Jones C, Lok IH, Haines CJ, Chan HC. Characterization of epithelial cell culture from human hydrosalpinges and effects of its conditioned medium on embryo development and sperm motility. Human Reproduction (Oxford, England). 18: 291-8. PMID 12571164 DOI: 10.1093/humrep/deg078  0.32
2002 Zhu JX, Lo PS, Zhao WC, Tang N, Zhou Q, Rowlands DK, Gou YL, Chung YW, Chan HC. Bak Foong Pills stimulate anion secretion across normal and cystic fibrosis pancreatic duct epithelia. Cell Biology International. 26: 1011-8. PMID 12468376 DOI: 10.1006/cbir.2002.0960  0.36
2001 Jiang JL, Zhou Q, Yu MK, Ho LS, Chen ZN, Chan HC. The Involvement of HAb18G/CD147 in Regulation of Store-operated Calcium Entry and Metastasis of Human Hepatoma Cells Journal of Biological Chemistry. 276: 46870-46877. PMID 11591720 DOI: 10.1074/jbc.M108291200  0.32
2001 Rowlands DK, Tsang LL, Cui YG, Chung YW, Chan LN, Liu CQ, James T, Chan HC. Upregulation of cystic fibrosis transmembrane conductance regulator expression by oestrogen and Bak Foong Pill in mouse uteri Cell Biology International. 25: 1033-1035. PMID 11589624 DOI: 10.1006/cbir.2001.0746  0.32
2001 Fiscus RR, Leung CPC, Yuen JPS, Chan HC. Quantification of apoptotic DNA fragmentation in a transformed uterine epithelial cell line, HRE-H9, using capillary electrophoresis with laser-induced fluorescence detector (CE-LIF) Cell Biology International. 25: 1007-1011. PMID 11589618 DOI: 10.1006/cbir.2001.0747  0.32
2001 Leung PS, So SC, Lam SY, Tsang LL, Chung YW, Chan HC. Local regulation of anion secretion by pituitary adenylate cyclase-activating polypeptide in human colonic T84 cells. Cell Biology International. 25: 123-9. PMID 11237416 DOI: 10.1006/cbir.2000.0584  0.4
2001 Chan HC. Epithelial cell biology: An interface with multidisciplines in life sciences. Introducing selected papers from the symposium on Epithelial Cell Biology, Beijing, China, 2000 Cell Biology International. 25: 991-992. DOI: 10.1006/cbir.2001.0748  0.32
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