Rony Seger - Publications

Affiliations: 
BIR Biological Regulation Weizmann Institute of Science, Rehovot, Israel 
Area:
Cell Biology, Molecular Biology

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kraus S, Benard O, Naor Z, Seger R. C-Src is Activated by the EGF Receptor in a Pathway that Mediates JNK and ERK Activation by Gonadotropin-Releasing Hormone in COS7 Cells. International Journal of Molecular Sciences. 21. PMID 33202981 DOI: 10.3390/ijms21228575  0.6
2020 Chuderland D, Marmor G, Shainskaya A, Seger R. Calcium-Mediated Interactions Regulate the Subcellular Localization of Extracellular Signal-Regulated Kinases (ERKs). Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 54: 474-492. PMID 32392404 DOI: 10.33594/000000231  1
2019 Plotnikov A, Chuderland D, Karamansha Y, Livnah O, Seger R. Nuclear ERK Translocation is Mediated by Protein Kinase CK2 and Accelerated by Autophosphorylation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 53: 366-387. PMID 31385665 DOI: 10.33594/000000144  1
2018 Nadel G, Yao Z, Ben-Ami I, Naor Z, Seger R. Gq-Induced Apoptosis is Mediated by AKT Inhibition That Leads to PKC-Induced JNK Activation. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 50: 121-135. PMID 30278445 DOI: 10.1159/000493963  0.6
2018 Konson A, Pradeep S, D'Acunto CW, Seger R. Pigment Epithelium-Derived Factor and its Phosphomimetic Mutant Induce JNK-Dependent Apoptosis and P38-Mediated Migration Arrest. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 49: 512-529. PMID 30157491 DOI: 10.1159/000492990  0.8
2018 Plotnikov A, Chuderland D, Karamansha Y, Livnah O, Seger R. Retraction for Plotnikov et al., "Nuclear Extracellular Signal-Regulated Kinase 1 and 2 Translocation Is Mediated by Casein Kinase 2 and Accelerated by Autophosphorylation". Molecular and Cellular Biology. 38. PMID 29764996 DOI: 10.1128/Mcb.00106-18  1
2017 Birkner K, Wasser B, Loos J, Plotnikov A, Seger R, Zipp F, Witsch E, Bittner S. The Role of ERK Signaling in Experimental Autoimmune Encephalomyelitis. International Journal of Molecular Sciences. 18. PMID 28914804 DOI: 10.3390/Ijms18091990  0.6
2017 Aebersold DM, Shaul YD, Yung Y, Yarom N, Yao Z, Hanoch T, Seger R. Correction for Aebersold et al., "Extracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function". Molecular and Cellular Biology. 37. PMID 28847972 DOI: 10.1128/Mcb.00322-17  0.6
2017 Rahamim-Ben Navi L, Tsukerman A, Feldman A, Melamed P, Tomić M, Stojilkovic SS, Boehm U, Seger R, Naor Z. GnRH Induces ERK-Dependent Bleb Formation in Gonadotrope Cells, Involving Recruitment of Members of a GnRH Receptor-Associated Signalosome to the Blebs. Frontiers in Endocrinology. 8: 113. PMID 28626446 DOI: 10.3389/Fendo.2017.00113  0.6
2017 Benard O, Naor Z, Seger R. Role of dynamin, Src, and Ras in the protein kinase C-mediated activation of ERK by gonadotropin-releasing hormone. The Journal of Biological Chemistry. 292: 8855. PMID 28550141 DOI: 10.1074/Jbc.M006995200  0.6
2017 Yung Y, Yao Z, Hanoch T, Seger R. ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK. The Journal of Biological Chemistry. 292: 8854. PMID 28550140 DOI: 10.1074/Jbc.M910060199  0.6
2017 Wolf I, Rubinfeld H, Yoon S, Marmor G, Hanoch T, Seger R. Involvement of the activation loop of ERK in the detachment from cytosolic anchoring. The Journal of Biological Chemistry. 292: 8853. PMID 28550139 DOI: 10.1074/Jbc.M103352200  0.52
2017 Yung Y, Yao Z, Aebersold DM, Hanoch T, Seger R. Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs. The Journal of Biological Chemistry. 292: 8852. PMID 28550138 DOI: 10.1074/Jbc.M105995200  0.6
2017 Kraus S, Benard O, Naor Z, Seger R. c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. The Journal of Biological Chemistry. 292: 8851. PMID 28550137 DOI: 10.1074/jbc.A117.303886  0.6
2017 Chuderland D, Marmor G, Shainskaya A, Seger R. Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases. The Journal of Biological Chemistry. 292: 8850. PMID 28550136 DOI: 10.1074/Jbc.A117.709030  1
2017 Konson A, Pradeep S, D'Acunto CW, Seger R. Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. The Journal of Biological Chemistry. 292: 8849. PMID 28550135 DOI: 10.1074/jbc.A110.151548  0.8
2017 Ben-Ami I, Yao Z, Naor Z, Seger R. Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation. The Journal of Biological Chemistry. 292: 8848. PMID 28550134 DOI: 10.1074/jbc.A111.247726  0.6
2016 Rahamim Ben-Navi L, Almog T, Yao Z, Seger R, Naor Z. A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa. Scientific Reports. 6: 37922. PMID 27901058 DOI: 10.1038/Srep37922  0.6
2016 Mugami S, Kravchook S, Navi LR, Seger R, Naor Z. Differential roles of PKC isoforms (PKCs) and Ca(2+) in GnRH and phorbol 12-myristate 13-acetate (PMA) stimulation of p38MAPK phosphorylation in immortalized gonadotrope cells. Molecular and Cellular Endocrinology. PMID 27810601 DOI: 10.1016/J.Mce.2016.10.031  0.6
2015 Bar-Lev TH, Harris D, Tomić M, Stojilkovic S, Blumenfeld Z, Brown P, Seger R, Naor Z. Role of PI4K and PI3K-AKT in ERK1/2 activation by GnRH in the pituitary gonadotropes. Molecular and Cellular Endocrinology. 415: 12-23. PMID 26238084 DOI: 10.1016/J.Mce.2015.07.029  0.6
2015 Plotnikov A, Flores K, Maik-Rachline G, Zehorai E, Kapri-Pardes E, Berti DA, Hanoch T, Besser MJ, Seger R. The nuclear translocation of ERK1/2 as an anticancer target. Nature Communications. 6: 6685. PMID 25819065 DOI: 10.1038/Ncomms7685  0.6
2014 Michailovici I, Harrington HA, Azogui HH, Yahalom-Ronen Y, Plotnikov A, Ching S, Stumpf MPH, Klein OD, Seger R, Tzahor E. Nuclear to cytoplasmic shuttling of ERK promotes differentiation of muscle stem/progenitor cells Development (Cambridge). 141: 2611-2620. PMID 24924195 DOI: 10.1242/Dev.107078  0.6
2013 Sviridonov L, Dobkin-Bekman M, Shterntal B, Przedecki F, Formishell L, Kravchook S, Rahamim-Ben Navi L, Bar-Lev TH, Kazanietz MG, Yao Z, Seger R, Naor Z. Differential signaling of the GnRH receptor in pituitary gonadotrope cell lines and prostate cancer cell lines. Molecular and Cellular Endocrinology. 369: 107-18. PMID 23380421 DOI: 10.1016/J.Mce.2013.01.010  0.6
2012 Michailovici I, Hay H, Plotnikov A, Seger R, Tzahor E. FGF signaling in head muscle development F1000research. 3. DOI: 10.7490/F1000Research.1092761.1  0.6
2011 Ben-Ami I, Yao Z, Naor Z, Seger R. Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation. The Journal of Biological Chemistry. 286: 31022-31. PMID 21757743 DOI: 10.1074/Jbc.M111.247726  0.6
2011 Plotnikov A, Chuderland D, Karamansha Y, Livnah O, Seger R. Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. Molecular and Cellular Biology. 31: 3515-30. PMID 21730285 DOI: 10.1128/Mcb.05424-11  1
2011 Plotnikov A, Zehorai E, Procaccia S, Seger R. The MAPK cascades: signaling components, nuclear roles and mechanisms of nuclear translocation. Biochimica Et Biophysica Acta. 1813: 1619-33. PMID 21167873 DOI: 10.1016/J.Bbamcr.2010.12.012  0.6
2011 Konson A, Pradeep S, D'Acunto CW, Seger R. Pigment epithelium-derived factor and its phosphomimetic mutant induce JNK-dependent apoptosis and p38-mediated migration arrest. The Journal of Biological Chemistry. 286: 3540-51. PMID 21059648 DOI: 10.1074/Jbc.M110.151548  0.8
2010 Yao Z, Yoon S, Kalie E, Raviv Z, Seger R. Calcium regulation of EGF-induced ERK5 activation: role of Lad1-MEKK2 interaction. Plos One. 5: e12627. PMID 20830310 DOI: 10.1371/Journal.Pone.0012627  0.6
2010 Procaccia S, Kraus S, Seger R. Determination of ERK activity: anti-phospho-ERK antibodies and in vitro phosphorylation. Methods in Molecular Biology (Clifton, N.J.). 661: 39-58. PMID 20811975 DOI: 10.1007/978-1-60761-795-2_2  0.6
2010 Dobkin-Bekman M, Rahamin-Ben Navi L, Ben-Navi LR, Shterntal B, Sviridonov L, Przedecki F, Naidich-Exler M, Brodie C, Seger R, Naor Z. Differential role of PKC isoforms in GnRH and phorbol 12-myristate 13-acetate activation of extracellular signal-regulated kinase and Jun N-terminal kinase. Endocrinology. 151: 4894-907. PMID 20810567 DOI: 10.1210/En.2010-0114  0.6
2010 Tirosh-Finkel L, Zeisel A, Brodt-Ivenshitz M, Shamai A, Yao Z, Seger R, Domany E, Tzahor E. BMP-mediated inhibition of FGF signaling promotes cardiomyocyte differentiation of anterior heart field progenitors. Development (Cambridge, England). 137: 2989-3000. PMID 20702560 DOI: 10.1242/Jcs.079764  0.6
2010 Konson A, Pradeep S, Seger R. Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents. Cancer Research. 70: 6247-57. PMID 20610633 DOI: 10.1158/0008-5472.Can-10-0434  0.8
2010 Zehorai E, Yao Z, Plotnikov A, Seger R. The subcellular localization of MEK and ERK--a novel nuclear translocation signal (NTS) paves a way to the nucleus. Molecular and Cellular Endocrinology. 314: 213-20. PMID 19406201 DOI: 10.1016/J.Mce.2009.04.008  0.6
2009 Shaul YD, Gibor G, Plotnikov A, Seger R. Specific phosphorylation and activation of ERK1c by MEK1b: a unique route in the ERK cascade. Genes & Development. 23: 1779-90. PMID 19651986 DOI: 10.1101/Gad.523909  0.6
2009 Dobkin-Bekman M, Naidich M, Rahamim L, Przedecki F, Almog T, Lim S, Melamed P, Liu P, Wohland T, Yao Z, Seger R, Naor Z. A preformed signaling complex mediates GnRH-activated ERK phosphorylation of paxillin and FAK at focal adhesions in L beta T2 gonadotrope cells. Molecular Endocrinology (Baltimore, Md.). 23: 1850-64. PMID 19628583 DOI: 10.1210/Me.2008-0260  0.6
2009 Yao Z, Seger R. The ERK signaling cascade--views from different subcellular compartments. Biofactors (Oxford, England). 35: 407-16. PMID 19565474 DOI: 10.1002/Biof.52  0.6
2008 Chuderland D, Seger R. Calcium regulates ERK signaling by modulating its protein-protein interactions. Communicative & Integrative Biology. 1: 4-5. PMID 19704446 DOI: 10.4161/Cib.1.1.6107  1
2008 Chuderland D, Konson A, Seger R. Identification and characterization of a general nuclear translocation signal in signaling proteins. Molecular Cell. 31: 850-61. PMID 18760948 DOI: 10.1016/J.Molcel.2008.08.007  1
2008 Almog T, Lazar S, Reiss N, Etkovitz N, Milch E, Rahamim N, Dobkin-Bekman M, Rotem R, Kalina M, Ramon J, Raziel A, Breitbart H, Brietbart H, Seger R, Naor Z. Identification of extracellular signal-regulated kinase 1/2 and p38 MAPK as regulators of human sperm motility and acrosome reaction and as predictors of poor spermatozoan quality. The Journal of Biological Chemistry. 283: 14479-89. PMID 18372245 DOI: 10.1074/Jbc.M710492200  0.6
2008 Chuderland D, Marmor G, Shainskaya A, Seger R. Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases. The Journal of Biological Chemistry. 283: 11176-88. PMID 18268018 DOI: 10.1074/jbc.M709030200  1
2007 Friedman J, Kraus S, Hauptman Y, Schiff Y, Seger R. Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. The Biochemical Journal. 405: 559-68. PMID 17456048 DOI: 10.1042/Bj20061653  0.6
2007 Cohen-Armon M, Visochek L, Rozensal D, Kalal A, Geistrikh I, Klein R, Bendetz-Nezer S, Yao Z, Seger R. DNA-independent PARP-1 activation by phosphorylated ERK2 increases Elk1 activity: a link to histone acetylation. Molecular Cell. 25: 297-308. PMID 17244536 DOI: 10.1016/J.Molcel.2006.12.012  0.6
2007 Burgermeister E, Chuderland D, Hanoch T, Meyer M, Liscovitch M, Seger R. Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma. Molecular and Cellular Biology. 27: 803-17. PMID 17101779 DOI: 10.1128/Mcb.00601-06  1
2006 Ben-Ami I, Freimann S, Armon L, Dantes A, Strassburger D, Friedler S, Raziel A, Seger R, Ron-El R, Amsterdam A. PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation. Molecular Human Reproduction. 12: 593-9. PMID 16888076 DOI: 10.1093/Molehr/Gal068  0.6
2006 Dobkin-Bekman M, Naidich M, Pawson AJ, Millar RP, Seger R, Naor Z. Activation of mitogen-activated protein kinase (MAPK) by GnRH is cell-context dependent. Molecular and Cellular Endocrinology. 252: 184-90. PMID 16682115 DOI: 10.1016/J.Mce.2006.03.035  0.6
2006 Kraus S, Naor Z, Seger R. Gonadotropin-releasing hormone in apoptosis of prostate cancer cells. Cancer Letters. 234: 109-23. PMID 16546667 DOI: 10.1016/J.Canlet.2005.02.038  0.6
2005 Chuderland D, Seger R. Protein-protein interactions in the regulation of the extracellular signal-regulated kinase. Molecular Biotechnology. 29: 57-74. PMID 15668520 DOI: 10.1385/Mb:29:1:57  1
2004 Aebersold DM, Shaul YD, Yung Y, Yarom N, Yao Z, Hanoch T, Seger R. Extracellular signal-regulated kinase 1c (ERK1c), a novel 42-kilodalton ERK, demonstrates unique modes of regulation, localization, and function. Molecular and Cellular Biology. 24: 10000-15. PMID 15509801 DOI: 10.1128/Mcb.24.22.10000-10015.2004  0.6
2004 Kraus S, Levy G, Hanoch T, Naor Z, Seger R. Gonadotropin-releasing hormone induces apoptosis of prostate cancer cells: role of c-Jun NH2-terminal kinase, protein kinase B, and extracellular signal-regulated kinase pathways. Cancer Research. 64: 5736-44. PMID 15313914 DOI: 10.1158/0008-5472.Can-04-1156  0.6
2004 Kraus S, Seger R. Determination of ERK activity: antiphospho-ERK antibodies, in vitro phosphorylation, and in-gel kinase assay. Methods in Molecular Biology (Clifton, N.J.). 250: 29-48. PMID 14755078 DOI: 10.1385/1-59259-671-1:29  0.6
2004 Bonfil D, Chuderland D, Kraus S, Shahbazian D, Friedberg I, Seger R, Naor Z. Extracellular signal-regulated kinase, Jun N-terminal kinase, p38, and c-Src are involved in gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone follicle-stimulating hormone β-subunit promoter Endocrinology. 145: 2228-2244. PMID 14736735 DOI: 10.1210/En.2003-1418  1
2003 Kraus S, Benard O, Naor Z, Seger R. c-Src is activated by the epidermal growth factor receptor in a pathway that mediates JNK and ERK activation by gonadotropin-releasing hormone in COS7 cells. The Journal of Biological Chemistry. 278: 32618-30. PMID 12750372 DOI: 10.1074/Jbc.M303886200  0.6
2003 Tajima K, Dantes A, Yao Z, Sorokina K, Kotsuji F, Seger R, Amsterdam A. Down-regulation of steroidogenic response to gonadotropins in human and rat preovulatory granulosa cells involves mitogen-activated protein kinase activation and modulation of DAX-1 and steroidogenic factor-1. The Journal of Clinical Endocrinology and Metabolism. 88: 2288-99. PMID 12727988 DOI: 10.1210/Jc.2002-020913  0.6
2003 Harris D, Chuderland D, Bonfil D, Kraus S, Seger R, Naor Z. Extracellular signal-regulated kinase and c-Src, but not Jun N-terminal kinase, are involved in basal and gonadotropin-releasing hormone-stimulated activity of the glycoprotein hormone alpha-subunit promoter. Endocrinology. 144: 612-22. PMID 12538624 DOI: 10.1210/En.2002-220690  1
2002 Harris D, Bonfil D, CHuderland D, Kraus S, Seger R, Naor Z. Activation of MAPK Cascades by GnRH: ERK and Jun N-Terminal Kinase Are Involved in Basal and GnRH-Stimulated Activity of the Glycoprotein Hormone LHβ-Subunit Promoter. Endocrinology. 143: 1018-1025. PMID 28201441 DOI: 10.1210/endo.143.3.8675  1
2002 Harris D, Bonfil D, Chuderland D, Kraus S, Seger R, Naor Z. Activation of MAPK cascades by GnRH: ERK and Jun N-terminal kinase are involved in basal and GnRH-stimulated activity of the glycoprotein hormone LHbeta-subunit promoter. Endocrinology. 143: 1018-25. PMID 11861527 DOI: 10.1210/Endo.143.3.8675  1
2001 Yao Z, Seger R. Immunological detection of phosphorylation Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. PMID 18228325 DOI: 10.1002/0471143030.Cb1402S00  0.6
2001 Yao Z, Flash I, Raviv Z, Yung Y, Asscher Y, Pleban S, Seger R. Non-regulated and stimulated mechanisms cooperate in the nuclear accumulation of MEK1. Oncogene. 20: 7588-96. PMID 11753637 DOI: 10.1038/Sj.Onc.1204963  0.6
2001 Kraus S, Naor Z, Seger R. Intracellular Signaling Pathways Mediated by the Gonadotropin-Releasing Hormone (GnRH) Receptor Archives of Medical Research. 32: 499-509. PMID 11750725 DOI: 10.1016/S0188-4409(01)00331-9  0.6
2001 Shacham S, Harris D, Ben-Shlomo H, Cohen I, Bonfil D, Przedecki F, Lewy H, Ashkenazi IE, Seger R, Naor Z. Mechanism of GnRH receptor signaling on gonadotropin release and gene expression in pituitary gonadotrophs. Vitamins and Hormones. 63: 63-90. PMID 11358118 DOI: 10.1016/S0083-6729(01)63003-6  0.6
2000 Naor Z, Benard O, Seger R. Activation of MAPK Cascades by G-protein-coupled Receptors: The Case of Gonadotropin-releasing Hormone Receptor Trends in Endocrinology and Metabolism. 11: 91-99. PMID 10707049 DOI: 10.1016/S1043-2760(99)00232-5  0.6
2000 Yao Z, Dolginov Y, Hanoch T, Yung Y, Ridner G, Lando Z, Zharhary D, Seger R. Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases Febs Letters. 468: 37-42. PMID 10683437 DOI: 10.1016/S0014-5793(00)01191-1  0.6
1997 Reiss N, Llevi LN, Shacham S, Harris D, Seger R, Naor Z. Mechanism of Mitogen-Activated Protein Kinase Activation by Gonadotropin-Releasing Hormone in the Pituitary αT3-1 Cell Line: Differential Roles of Calcium and Protein Kinase C. Endocrinology. 138: 1673-1682. PMID 28199612 DOI: 10.1210/Endo.138.4.5057  0.6
1997 Yung Y, Dolginov Y, Yao Z, Rubinfeld H, Michael D, Hanoch T, Roubini E, Lando Z, Zharhary D, Seger R. Detection of ERK activation by a novel monoclonal antibody. Febs Letters. 408: 292-6. PMID 9188779 DOI: 10.1016/S0014-5793(97)00442-0  0.6
1995 Naor Z, Shacham S, Harris D, Seger R, Reiss N. Signal transduction of the gonadotropin releasing hormone (GnRH) receptor: cross-talk of calcium, protein kinase C (PKC), and arachidonic acid. Cellular and Molecular Neurobiology. 15: 527-544. PMID 8719039 DOI: 10.1007/Bf02071315  0.6
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