Steven B. McMahon - Publications

University of Pennsylvania, Philadelphia, PA, United States 
Molecular Biology, Cell Biology

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 McCann JJ, Vasilevskaya IA, Poudel Neupane N, Shafi AA, McNair C, Dylgjeri E, Mandigo AC, Schiewer MJ, Schrecengost RS, Gallagher P, Stanek TJ, McMahon SB, Berman-Booty LD, Ostrander WF, Knudsen KE. USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair. Cancer Research. PMID 31740444 DOI: 10.1158/0008-5472.CAN-19-1033  0.36
2018 Gennaro VJ, Stanek TJ, Peck AR, Sun Y, Wang F, Qie S, Knudsen KE, Rui H, Butt T, Diehl JA, McMahon SB. Control of CCND1 ubiquitylation by the catalytic SAGA subunit USP22 is essential for cell cycle progression through G1 in cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224477 DOI: 10.1073/pnas.1807704115  0.36
2016 Oran AR, Adams CM, Zhang XY, Gennaro VJ, Pfeiffer HK, Mellert HS, Seidel HE, Mascioli K, Kaplan J, Gaballa MR, Shen C, Rigoutsos I, King MP, Cotney JL, Arnold JJ, ... ... McMahon SB, et al. Multi-focal control of mitochondrial gene expression by oncogenic MYC provides potential therapeutic targets in cancer. Oncotarget. PMID 27590350 DOI: 10.18632/oncotarget.11718  0.64
2016 Monteith JA, Mellert H, Sammons MA, Kuswanto LA, Sykes SM, Resnick-Silverman L, Manfredi JJ, Berger SL, McMahon SB. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction. Molecular Oncology. PMID 27341992 DOI: 10.1016/j.molonc.2016.05.007  0.48
2015 Tutton S, Azzam GA, Stong N, Vladimirova O, Wiedmer A, Monteith JA, Beishline K, Wang Z, Deng Z, Riethman H, McMahon SB, Murphy M, Lieberman PM. Subtelomeric p53 binding prevents accumulation of DNA damage at human telomeres. The Embo Journal. PMID 26658110 DOI: 10.15252/embj.201490880  0.48
2014 McMahon SB. MYC and the control of apoptosis. Cold Spring Harbor Perspectives in Medicine. 4: a014407. PMID 24985130 DOI: 10.1101/cshperspect.a014407  1
2014 Schrecengost RS, Dean JL, Goodwin JF, Schiewer MJ, Urban MW, Stanek TJ, Sussman RT, Hicks JL, Birbe RC, Draganova-Tacheva RA, Visakorpi T, DeMarzo AM, McMahon SB, Knudsen KE. USP22 regulates oncogenic signaling pathways to drive lethal cancer progression. Cancer Research. 74: 272-86. PMID 24197134 DOI: 10.1158/0008-5472.CAN-13-1954  1
2013 Chen K, Wu K, Gormley M, Ertel A, Wang J, Zhang W, Zhou J, Disante G, Li Z, Rui H, Quong AA, McMahon SB, Deng H, Lisanti MP, Wang C, et al. Acetylation of the cell-fate factor dachshund determines p53 binding and signaling modules in breast cancer. Oncotarget. 4: 923-35. PMID 23798621  1
2013 Sussman RT, Stanek TJ, Esteso P, Gearhart JD, Knudsen KE, McMahon SB. The epigenetic modifier ubiquitin-specific protease 22 (USP22) regulates embryonic stem cell differentiation via transcriptional repression of sex-determining region Y-box 2 (SOX2). The Journal of Biological Chemistry. 288: 24234-46. PMID 23760504 DOI: 10.1074/jbc.M113.469783  1
2013 Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, ... ... McMahon SB, et al. Dachshund binds p53 to block the growth of lung adenocarcinoma cells. Cancer Research. 73: 3262-74. PMID 23492369 DOI: 10.1158/0008-5472.CAN-12-3191  1
2013 Armour SM, Bennett EJ, Braun CR, Zhang XY, McMahon SB, Gygi SP, Harper JW, Sinclair DA. A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex. Molecular and Cellular Biology. 33: 1487-502. PMID 23382074 DOI: 10.1128/MCB.00971-12  1
2012 Yuan H, Rossetto D, Mellert H, Dang W, Srinivasan M, Johnson J, Hodawadekar S, Ding EC, Speicher K, Abshiru N, Perry R, Wu J, Yang C, Zheng YG, Speicher DW, ... ... McMahon SB, et al. MYST protein acetyltransferase activity requires active site lysine autoacetylation. The Embo Journal. 31: 58-70. PMID 22020126 DOI: 10.1038/emboj.2011.382  1
2011 Zhang XY, Pfeiffer HK, Mellert HS, Stanek TJ, Sussman RT, Kumari A, Yu D, Rigoutsos I, Thomas-Tikhonenko A, Seidel HE, Chodosh LA, Packham G, Baserga R, McMahon SB. Inhibition of the single downstream target BAG1 activates the latent apoptotic potential of MYC. Molecular and Cellular Biology. 31: 5037-45. PMID 21986497 DOI: 10.1128/MCB.06297-11  1
2011 Charvet C, Wissler M, Brauns-Schubert P, Wang SJ, Tang Y, Sigloch FC, Mellert H, Brandenburg M, Lindner SE, Breit B, Green DR, McMahon SB, Borner C, Gu W, Maurer U. Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Molecular Cell. 42: 584-96. PMID 21658600 DOI: 10.1016/j.molcel.2011.03.033  1
2011 Sussman RT, Zhang XY, McMahon SB. Enzymatic assays for assessing histone deubiquitylation activity. Methods (San Diego, Calif.). 54: 339-47. PMID 21513801 DOI: 10.1016/j.ymeth.2011.04.001  1
2011 Mellert HS, Stanek TJ, Sykes SM, Rauscher FJ, Schultz DC, McMahon SB. Deacetylation of the DNA-binding domain regulates p53-mediated apoptosis. The Journal of Biological Chemistry. 286: 4264-70. PMID 21148320 DOI: 10.1074/jbc.M110.184663  1
2011 La Rocca G, Shi B, Audia A, Ferrari-Amorotti G, Mellert HS, Calabretta B, McMahon SB, Sepp-Lorenzino L, Baserga R. Regulation of microRNA-145 by growth arrest and differentiation. Experimental Cell Research. 317: 488-95. PMID 21111732 DOI: 10.1016/j.yexcr.2010.11.010  0.64
2010 Van Dang C, McMahon SB. Emerging Concepts in the Analysis of Transcriptional Targets of the MYC Oncoprotein: Are the Targets Targetable? Genes & Cancer. 1: 560-567. PMID 21533016 DOI: 10.1177/1947601910379011  1
2010 Aggarwal P, Vaites LP, Kim JK, Mellert H, Gurung B, Nakagawa H, Herlyn M, Hua X, Rustgi AK, McMahon SB, Diehl JA. Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase. Cancer Cell. 18: 329-40. PMID 20951943 DOI: 10.1016/j.ccr.2010.08.012  1
2010 Norvell A, McMahon SB. Cell biology. Rise of the rival. Science (New York, N.Y.). 327: 964-5. PMID 20167774 DOI: 10.1126/science.1187159  1
2009 Mellert HS, McMahon SB. hMOF, a KAT(8) with many lives. Molecular Cell. 36: 174-5. PMID 19854127 DOI: 10.1016/j.molcel.2009.10.005  0.64
2009 Mellert HS, McMahon SB. Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells. Trends in Biochemical Sciences. 34: 571-8. PMID 19819149 DOI: 10.1016/j.tibs.2009.06.010  0.64
2009 Sykes SM, Stanek TJ, Frank A, Murphy ME, McMahon SB. Acetylation of the DNA binding domain regulates transcription-independent apoptosis by p53. The Journal of Biological Chemistry. 284: 20197-205. PMID 19494119 DOI: 10.1074/jbc.M109.026096  0.48
2008 Wise DR, DeBerardinis RJ, Mancuso A, Sayed N, Zhang XY, Pfeiffer HK, Nissim I, Daikhin E, Yudkoff M, McMahon SB, Thompson CB. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. Proceedings of the National Academy of Sciences of the United States of America. 105: 18782-7. PMID 19033189 DOI: 10.1073/pnas.0810199105  1
2008 Pietsch EC, Sykes SM, McMahon SB, Murphy ME. The p53 family and programmed cell death. Oncogene. 27: 6507-21. PMID 18955976 DOI: 10.1038/onc.2008.315  1
2008 McMahon SB. Control of nucleotide biosynthesis by the MYC oncoprotein. Cell Cycle (Georgetown, Tex.). 7: 2275-6. PMID 18682683  1
2008 Zhang XY, Varthi M, Sykes SM, Phillips C, Warzecha C, Zhu W, Wyce A, Thorne AW, Berger SL, McMahon SB. The putative cancer stem cell marker USP22 is a subunit of the human SAGA complex required for activated transcription and cell-cycle progression. Molecular Cell. 29: 102-11. PMID 18206973 DOI: 10.1016/j.molcel.2007.12.015  1
2007 Mellert H, Sykes SM, Murphy ME, McMahon SB. The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain. Cell Cycle (Georgetown, Tex.). 6: 1304-6. PMID 17534149  0.48
2007 Patel JH, McMahon SB. BCL2 is a downstream effector of MIZ-1 essential for blocking c-MYC-induced apoptosis. The Journal of Biological Chemistry. 282: 5-13. PMID 17082179 DOI: 10.1074/jbc.M609138200  1
2006 Sykes SM, Mellert HS, Holbert MA, Li K, Marmorstein R, Lane WS, McMahon SB. Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Molecular Cell. 24: 841-51. PMID 17189187 DOI: 10.1016/j.molcel.2006.11.026  1
2006 Chau CM, Zhang XY, McMahon SB, Lieberman PM. Regulation of Epstein-Barr virus latency type by the chromatin boundary factor CTCF. Journal of Virology. 80: 5723-32. PMID 16731911 DOI: 10.1128/JVI.00025-06  1
2006 Knoepfler PS, Zhang XY, Cheng PF, Gafken PR, McMahon SB, Eisenman RN. Myc influences global chromatin structure. The Embo Journal. 25: 2723-34. PMID 16724113 DOI: 10.1038/sj.emboj.7601152  1
2006 Patel JH, McMahon SB. Targeting of Miz-1 is essential for Myc-mediated apoptosis. The Journal of Biological Chemistry. 281: 3283-9. PMID 16352593 DOI: 10.1074/jbc.M513038200  1
2005 Zhang XY, DeSalle LM, Patel JH, Capobianco AJ, Yu D, Thomas-Tikhonenko A, McMahon SB. Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein. Proceedings of the National Academy of Sciences of the United States of America. 102: 13968-73. PMID 16172399 DOI: 10.1073/pnas.0502330102  1
2004 Patel JH, Du Y, Ard PG, Phillips C, Carella B, Chen CJ, Rakowski C, Chatterjee C, Lieberman PM, Lane WS, Blobel GA, McMahon SB. The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60. Molecular and Cellular Biology. 24: 10826-34. PMID 15572685 DOI: 10.1128/MCB.24.24.10826-10834.2004  1
2004 Patel JH, Loboda AP, Showe MK, Showe LC, McMahon SB. Analysis of genomic targets reveals complex functions of MYC. Nature Reviews. Cancer. 4: 562-8. PMID 15229481 DOI: 10.1038/nrc1393  1
2002 Nikiforov MA, Chandriani S, Park J, Kotenko I, Matheos D, Johnsson A, McMahon SB, Cole MD. TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins. Molecular and Cellular Biology. 22: 5054-63. PMID 12077335 DOI: 10.1128/MCB.22.14.5054-5063.2002  1
2002 Yanagisawa J, Kitagawa H, Yanagida M, Wada O, Ogawa S, Nakagomi M, Oishi H, Yamamoto Y, Nagasawa H, McMahon SB, Cole MD, Tora L, Takahashi N, Kato S. Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Molecular Cell. 9: 553-62. PMID 11931763 DOI: 10.1016/S1097-2765(02)00478-1  1
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