Stephen I. Rennard - Publications

Affiliations: 
University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Cell Biology, Pathology, Physiology Biology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Ikari J, Nelson AJ, Obaid J, Giron-Martinez A, Ikari K, Makino F, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Demeo D, Feghali-Bostwick C, Holz O, Rabe K, ... ... Rennard SI, et al. Reduced microRNA-503 expression augments lung fibroblast VEGF production in chronic obstructive pulmonary disease. Plos One. 12: e0184039. PMID 28880936 DOI: 10.1371/journal.pone.0184039  0.48
2016 Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Anzueto A, Alagappan VK, Siddiqui S, Rekeda L, Miller CJ, Zetterstrand S, Reisner C, Rennard SI. Effect of Roflumilast and Inhaled Corticosteroid/Long-Acting β2-Agonist on Chronic Obstructive Pulmonary Disease Exacerbations (RE(2)SPOND). A Randomized Clinical Trial. American Journal of Respiratory and Critical Care Medicine. 194: 559-67. PMID 27585384 DOI: 10.1164/rccm.201607-1349OC  0.32
2016 Rennard SI, Martinez FJ, Rabe KF, Sethi S, Pizzichini E, McIvor A, Siddiqui S, Anzueto A, Zhu H. Effects of roflumilast in COPD patients receiving inhaled corticosteroid/long-acting β2-agonist fixed-dose combination: RE(2)SPOND rationale and study design. International Journal of Chronic Obstructive Pulmonary Disease. 11: 1921-8. PMID 27574416 DOI: 10.2147/COPD.S109661  0.32
2016 Sun W, Kechris K, Jacobson S, Drummond MB, Hawkins GA, Yang J, Chen TH, Quibrera PM, Anderson W, Barr RG, Basta PV, Bleecker ER, Beaty T, Casaburi R, Castaldi P, ... ... Rennard SI, et al. Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD. Plos Genetics. 12: e1006011. PMID 27532455 DOI: 10.1371/journal.pgen.1006011  0.32
2016 Rabinovich RA, Miller BE, Wrobel K, Ranjit K, Williams MC, Drost E, Edwards LD, Lomas DA, Rennard SI, Agustí A, Tal-Singer R, Vestbo J, Wouters EF, John M, van Beek EJ, et al. Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD. The European Respiratory Journal. PMID 27009168 DOI: 10.1183/13993003.01824-2015  0.32
2016 Putcha N, Barr RG, Han MK, Woodruff PG, Bleecker ER, Kanner RE, Martinez FJ, Smith BM, Tashkin DP, Bowler RP, Eisner MD, Rennard SI, Wise RA, Hansel NN. Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort. Thorax. PMID 26962015 DOI: 10.1136/thoraxjnl-2015-207487  0.32
2016 Hobbs BD, Parker MM, Chen H, Lao T, Hardin M, Qiao D, Hawrylkiewicz I, Sliwinski P, Yim JJ, Kim WJ, Kim DK, Castaldi PJ, Hersh CP, Morrow J, Celli BR, ... ... Rennard SI, et al. Exome Array Analysis Identifies A Common Variant in IL27 Associated with Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 26771213 DOI: 10.1164/rccm.201510-2053OC  0.32
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí AA, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 159-72. PMID 26028628 DOI: 10.1183/16000617.00000315  0.32
2015 Leidy NK, Kim K, Bacci ED, Yawn BP, Mannino DM, Thomashow BM, Barr RG, Rennard SI, Houfek JF, Han MK, Meldrum CA, Make BJ, Bowler RP, Steenrod AW, Murray LT, et al. Identifying cases of undiagnosed, clinically significant COPD in primary care: qualitative insight from patients in the target population. Npj Primary Care Respiratory Medicine. 25: 15024. PMID 26028486 DOI: 10.1038/npjpcrm.2015.24  0.32
2015 Anzueto A, Jenkins CR, Make BJ, Lindberg M, Calverley PM, Fagerås M, Postma DS, Rennard SI, Tashkin DP. Efficacy of an inhaled corticosteroid/long-acting β2-agonist combination in symptomatic COPD patients in GOLD groups B and D. The European Respiratory Journal. 46: 255-8. PMID 26022947 DOI: 10.1183/09031936.00047115  0.32
2015 Yentes JM, Schmid KK, Blanke D, Romberger DJ, Rennard SI, Stergiou N. Gait mechanics in patients with chronic obstructive pulmonary disease. Respiratory Research. 16: 31. PMID 25849481 DOI: 10.1186/s12931-015-0187-5  0.32
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An Official American Thoracic Society/European Respiratory Society Statement: Research questions in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 191: e4-e27. PMID 25830527 DOI: 10.1164/rccm.201501-0044ST  0.32
2015 Celli BR, Decramer M, Wedzicha JA, Wilson KC, Agustí A, Criner GJ, MacNee W, Make BJ, Rennard SI, Stockley RA, Vogelmeier C, Anzueto A, Au DH, Barnes PJ, Burgel PR, et al. An official American Thoracic Society/European Respiratory Society statement: research questions in COPD. The European Respiratory Journal. 45: 879-905. PMID 25829431 DOI: 10.1183/09031936.00009015  0.32
2015 Wilke S, Jones PW, Müllerova H, Vestbo J, Tal-Singer R, Franssen FM, Agusti A, Bakke P, Calverley PM, Coxson HO, Crim C, Edwards LD, Lomas DA, MacNee W, Rennard SI, et al. One-year change in health status and subsequent outcomes in COPD. Thorax. 70: 420-5. PMID 25782757 DOI: 10.1136/thoraxjnl-2014-205697  0.32
2015 Rennard SI, Dale DC, Donohue JF, Kanniess F, Magnussen H, Sutherland ER, Watz H, Lu S, Stryszak P, Rosenberg E, Staudinger H. CXCR2 Antagonist MK-7123. A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. 191: 1001-11. PMID 25695403 DOI: 10.1164/rccm.201405-0992OC  0.32
2015 Ebbert JO, Hughes JR, West RJ, Rennard SI, Russ C, McRae TD, Treadow J, Yu CR, Dutro MP, Park PW. Effect of varenicline on smoking cessation through smoking reduction: a randomized clinical trial. Jama. 313: 687-94. PMID 25688780 DOI: 10.1001/jama.2015.280  0.32
2015 Freeman CM, Crudgington S, Stolberg VR, Brown JP, Sonstein J, Alexis NE, Doerschuk CM, Basta PV, Carretta EE, Couper DJ, Hastie AT, Kaner RJ, O'Neal WK, Paine R, Rennard SI, et al. Design of a multi-center immunophenotyping analysis of peripheral blood, sputum and bronchoalveolar lavage fluid in the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS). Journal of Translational Medicine. 13: 19. PMID 25622723 DOI: 10.1186/s12967-014-0374-z  0.32
2015 Morrow JD, Qiu W, Chhabra D, Rennard SI, Belloni P, Belousov A, Pillai SG, Hersh CP. Identifying a gene expression signature of frequent COPD exacerbations in peripheral blood using network methods. Bmc Medical Genomics. 8: 1. PMID 25582225 DOI: 10.1186/s12920-014-0072-y  0.32
2015 Ikari J, Smith LM, Nelson AJ, Iwasawa S, Gunji Y, Farid M, Wang X, Basma H, Feghali-Bostwick C, Liu X, DeMeo DL, Rennard SI. Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro. In Vitro Cellular & Developmental Biology. Animal. 51: 390-9. PMID 25552310 DOI: 10.1007/s11626-014-9820-8  0.32
2015 Li YJ, Kanaji N, Wang XQ, Sato T, Nakanishi M, Kim M, Michalski J, Nelson AJ, Farid M, Basma H, Patil A, Toews ML, Liu X, Rennard SI. Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition. Prostaglandins & Other Lipid Mediators. 116: 1-9. PMID 25460827 DOI: 10.1016/j.prostaglandins.2014.10.003  0.32
2014 Putcha N, Puhan MA, Drummond MB, Han MK, Regan EA, Hanania NA, Martinez CH, Foreman M, Bhatt SP, Make B, Ramsdell J, DeMeo DL, Barr RG, Rennard SI, Martinez F, et al. A simplified score to quantify comorbidity in COPD. Plos One. 9: e114438. PMID 25514500 DOI: 10.1371/journal.pone.0114438  0.32
2014 Hersh CP, Make BJ, Lynch DA, Barr RG, Bowler RP, Calverley PM, Castaldi PJ, Cho MH, Coxson HO, DeMeo DL, Foreman MG, Han MK, Harshfield BJ, Hokanson JE, Lutz S, ... ... Rennard SI, et al. Non-emphysematous chronic obstructive pulmonary disease is associated with diabetes mellitus. Bmc Pulmonary Medicine. 14: 164. PMID 25341556 DOI: 10.1186/1471-2466-14-164  0.32
2014 Bhatt SP, Wells JM, Kim V, Criner GJ, Hersh CP, Hardin M, Bailey WC, Nath H, Kim YI, Foreman MG, Stinson DS, Wilson CG, Rennard SI, Silverman EK, Make BJ, et al. Radiological correlates and clinical implications of the paradoxical lung function response to β₂ agonists: an observational study. The Lancet. Respiratory Medicine. 2: 911-8. PMID 25217076 DOI: 10.1016/S2213-2600(14)70185-7  0.32
2014 Janssen DJ, Müllerova H, Agusti A, Yates JC, Tal-Singer R, Rennard SI, Vestbo J, Wouters EF. Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort. Respiratory Medicine. 108: 1647-54. PMID 25135745 DOI: 10.1016/j.rmed.2014.07.013  0.32
2014 Menche J, Sharma A, Cho MH, Mayer RJ, Rennard SI, Celli B, Miller BE, Locantore N, Tal-Singer R, Ghosh S, Larminie C, Bradley G, Riley JH, Agusti A, Silverman EK, et al. A diVIsive Shuffling Approach (VIStA) for gene expression analysis to identify subtypes in Chronic Obstructive Pulmonary Disease. Bmc Systems Biology. 8: S8. PMID 25032995 DOI: 10.1186/1752-0509-8-S2-S8  0.32
2014 Rennard SI, Sun SX, Tourkodimitris S, Rowe P, Goehring UM, Bredenbröker D, Calverley PM. Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials. International Journal of Chronic Obstructive Pulmonary Disease. 9: 657-73. PMID 25018629 DOI: 10.2147/COPD.S55738  0.32
2014 Kanaji N, Basma H, Nelson A, Farid M, Sato T, Nakanishi M, Wang X, Michalski J, Li Y, Gunji Y, Feghali-Bostwick C, Liu X, Rennard SI. Fibroblasts that resist cigarette smoke-induced senescence acquire profibrotic phenotypes. American Journal of Physiology. Lung Cellular and Molecular Physiology. 307: L364-73. PMID 25015975 DOI: 10.1152/ajplung.00041.2014  0.48
2014 Wells JM, O'Reilly PJ, Szul T, Sullivan DI, Handley G, Garrett C, McNicholas CM, Roda MA, Miller BE, Tal-Singer R, Gaggar A, Rennard SI, Jackson PL, Blalock JE. An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 190: 51-61. PMID 24874071 DOI: 10.1164/rccm.201401-0145OC  0.32
2014 McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, ... Rennard SI, et al. Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. American Journal of Respiratory Cell and Molecular Biology. 51: 678-87. PMID 24825563 DOI: 10.1165/rcmb.2014-0135OC  0.32
2014 Drummond MB, Buist AS, Crapo JD, Wise RA, Rennard SI. Chronic obstructive pulmonary disease: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases. Annals of the American Thoracic Society. 11: S154-60. PMID 24754824 DOI: 10.1513/AnnalsATS.201312-432LD  0.32
2014 Kobayashi T, Kim H, Liu X, Sugiura H, Kohyama T, Fang Q, Wen FQ, Abe S, Wang X, Atkinson JJ, Shipley JM, Senior RM, Rennard SI. Matrix metalloproteinase-9 activates TGF-β and stimulates fibroblast contraction of collagen gels. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L1006-15. PMID 24705725 DOI: 10.1152/ajplung.00015.2014  0.32
2014 Tan L, Dickens JA, Demeo DL, Miranda E, Perez J, Rashid ST, Day J, Ordoñez A, Marciniak SJ, Haq I, Barker AF, Campbell EJ, Eden E, McElvaney NG, Rennard SI, et al. Circulating polymers in α1-antitrypsin deficiency. The European Respiratory Journal. 43: 1501-4. PMID 24603821 DOI: 10.1183/09031936.00111213  0.32
2014 McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, ... ... Rennard SI, et al. Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study. Annals of the American Thoracic Society. 11: 326-34. PMID 24558953 DOI: 10.1513/AnnalsATS.201307-229OC  0.32
2014 Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, et al. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. American Journal of Respiratory and Critical Care Medicine. 189: 1022-30. PMID 24552242 DOI: 10.1164/rccm.201311-2006PP  0.32
2014 Basma H, Gunji Y, Iwasawa S, Nelson A, Farid M, Ikari J, Liu X, Wang X, Michalski J, Smith L, Iqbal J, El Behery R, West W, Yelamanchili S, Rennard D, ... ... Rennard SI, et al. Reprogramming of COPD lung fibroblasts through formation of induced pluripotent stem cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L552-65. PMID 24487392 DOI: 10.1152/ajplung.00255.2013  0.48
2014 O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, ... ... Rennard SI, et al. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. Journal of Translational Medicine. 12: 9. PMID 24397870 DOI: 10.1186/1479-5876-12-9  0.32
2014 Faner R, Tal-Singer R, Riley JH, Celli B, Vestbo J, MacNee W, Bakke P, Calverley PM, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, Miller BE, Rennard SI, et al. Lessons from ECLIPSE: a review of COPD biomarkers. Thorax. 69: 666-72. PMID 24310110 DOI: 10.1136/thoraxjnl-2013-204778  0.32
2014 Liu X, Nelson A, Wang X, Farid M, Gunji Y, Ikari J, Iwasawa S, Basma H, Feghali-Bostwick C, Rennard SI. Vitamin D modulates prostaglandin E2 synthesis and degradation in human lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 50: 40-50. PMID 23941558 DOI: 10.1165/rcmb.2013-0211OC  0.48
2013 Coxson HO, Dirksen A, Edwards LD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Crim C, Duvoix A, Fauerbach PN, Lomas DA, Macnee W, Mayer RJ, Miller BE, ... ... Rennard SI, et al. The presence and progression of emphysema in COPD as determined by CT scanning and biomarker expression: a prospective analysis from the ECLIPSE study. The Lancet. Respiratory Medicine. 1: 129-36. PMID 24429093 DOI: 10.1016/S2213-2600(13)70006-7  0.32
2013 Fang Q, Ma Y, Wang J, Michalski J, Rennard SI, Liu X. PGE 2 desensitizes β -agonist effect on human lung fibroblast-mediated collagen gel contraction through upregulating PDE4. Mediators of Inflammation. 2013: 145197. PMID 24227907 DOI: 10.1155/2013/145197  0.48
2013 Rennard SI, Scanlon PD, Ferguson GT, Rekeda L, Maurer BT, Garcia Gil E, Caracta CF. ACCORD COPD II: a randomized clinical trial to evaluate the 12-week efficacy and safety of twice-daily aclidinium bromide in chronic obstructive pulmonary disease patients. Clinical Drug Investigation. 33: 893-904. PMID 24085591 DOI: 10.1007/s40261-013-0138-1  0.32
2013 Wang X, Nelson A, Weiler ZM, Patil A, Sato T, Kanaji N, Nakanishi M, Michalski J, Farid M, Basma H, Levan TD, Miller-Larsson A, Wieslander E, Muller KC, Holz O, ... ... Rennard SI, et al. Anti-inflammatory effects of budesonide in human lung fibroblast are independent of histone deacetylase 2. Journal of Inflammation Research. 6: 109-19. PMID 24062615 DOI: 10.2147/JIR.S43736  0.32
2013 Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustí A, Fabbri LM, ... ... Rennard SI, et al. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 188: 948-57. PMID 23947473 DOI: 10.1164/rccm.201302-0247OC  0.32
2013 Dodmane PR, Arnold LL, Kakiuchi-Kiyota S, Qiu F, Liu X, Rennard SI, Cohen SM. Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells. Toxicology. 312: 18-29. PMID 23876855 DOI: 10.1016/j.tox.2013.07.008  0.32
2013 Nagahama KY, Togo S, Holz O, Magnussen H, Liu X, Seyama K, Takahashi K, Rennard SI. Oncostatin M modulates fibroblast function via signal transducers and activators of transcription proteins-3. American Journal of Respiratory Cell and Molecular Biology. 49: 582-91. PMID 23668543 DOI: 10.1165/rcmb.2012-0460OC  0.36
2013 Ikari J, Michalski JM, Iwasawa S, Gunji Y, Nogel S, Park JH, Nelson AJ, Farid M, Wang X, Schulte N, Basma H, Toews ML, Feghali-Bostwick C, Tenor H, Liu X, ... Rennard SI, et al. Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2. American Journal of Respiratory Cell and Molecular Biology. 49: 571-81. PMID 23656623 DOI: 10.1165/rcmb.2013-0004OC  0.32
2013 Farid M, Kanaji N, Nakanishi M, Gunji Y, Michalski J, Iwasawa S, Ikari J, Wang X, Basma H, Nelson AJ, Liu X, Rennard SI. Smad3 mediates cigarette smoke extract (CSE) induction of VEGF release by human fetal lung fibroblasts. Toxicology Letters. 220: 126-34. PMID 23618901 DOI: 10.1016/j.toxlet.2013.04.011  0.48
2013 Fang Q, Schulte NA, Kim H, Kobayashi T, Wang X, Miller-Larsson A, Wieslander E, Toews ML, Liu X, Rennard SI. Effect of budesonide on fibroblast-mediated collagen gel contraction and degradation. Journal of Inflammation Research. 6: 25-33. PMID 23576875 DOI: 10.2147/JIR.S35136  0.32
2013 Zhou X, Qiu W, Sathirapongsasuti JF, Cho MH, Mancini JD, Lao T, Thibault DM, Litonjua AA, Bakke PS, Gulsvik A, Lomas DA, Beaty TH, Hersh CP, Anderson C, Geigenmuller U, ... ... Rennard SI, et al. Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells. Genomics. 101: 263-72. PMID 23459001 DOI: 10.1016/j.ygeno.2013.02.010  0.32
2013 Siedlinski M, Tingley D, Lipman PJ, Cho MH, Litonjua AA, Sparrow D, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, et al. Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility. Human Genetics. 132: 431-41. PMID 23299987 DOI: 10.1007/s00439-012-1262-3  0.32
2013 Kanaji N, Nelson A, Wang X, Sato T, Nakanishi M, Gunji Y, Basma H, Michalski J, Farid M, Rennard SI, Liu X. Differential roles of JNK, ERK1/2, and p38 mitogen-activated protein kinases on endothelial cell tissue repair functions in response to tumor necrosis factor-α. Journal of Vascular Research. 50: 145-56. PMID 23258237 DOI: 10.1159/000345525  0.48
2013 Rennard SI, Flavin SK, Agarwal PK, Lo KH, Barnathan ES. Long-term safety study of infliximab in moderate-to-severe chronic obstructive pulmonary disease. Respiratory Medicine. 107: 424-32. PMID 23246078 DOI: 10.1016/j.rmed.2012.11.008  0.32
2012 Wan ES, Qiu W, Baccarelli A, Carey VJ, Bacherman H, Rennard SI, Agustí A, Anderson WH, Lomas DA, DeMeo DL. Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 186: 1248-55. PMID 23065012 DOI: 10.1164/rccm.201207-1280OC  0.32
2012 Michalski J, Kanaji N, Liu X, Nogel S, Wang X, Basma H, Nakanishi M, Sato T, Gunji Y, Fahrid M, Nelson A, Muller KC, Holz O, Magnussen H, Rabe KF, ... ... Rennard SI, et al. Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4. American Journal of Respiratory Cell and Molecular Biology. 47: 729-37. PMID 23043089 DOI: 10.1165/rcmb.2012-0057OC  0.32
2012 Rennard SI, Bailey KL. Chronic obstructive pulmonary disease exacerbations: accurate and easy measurement promises much. American Journal of Respiratory and Critical Care Medicine. 185: 1139-41. PMID 22661519 DOI: 10.1164/rccm.201202-0227ED  0.32
2012 Agustí A, Edwards LD, Rennard SI, MacNee W, Tal-Singer R, Miller BE, Vestbo J, Lomas DA, Calverley PM, Wouters E, Crim C, Yates JC, Silverman EK, Coxson HO, Bakke P, et al. Persistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotype. Plos One. 7: e37483. PMID 22624038 DOI: 10.1371/journal.pone.0037483  0.32
2012 Siedlinski M, Klanderman B, Sandhaus RA, Barker AF, Brantly ML, Eden E, McElvaney NG, Rennard SI, Stocks JM, Stoller JK, Strange C, Turino GM, Campbell EJ, Demeo DL. Association of cigarette smoking and CRP levels with DNA methylation in α-1 antitrypsin deficiency. Epigenetics : Official Journal of the Dna Methylation Society. 7: 720-8. PMID 22617718 DOI: 10.4161/epi.20319  0.32
2012 Wan ES, Qiu W, Baccarelli A, Carey VJ, Bacherman H, Rennard SI, Agusti A, Anderson W, Lomas DA, Demeo DL. Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome. Human Molecular Genetics. 21: 3073-82. PMID 22492999 DOI: 10.1093/hmg/dds135  0.32
2012 Kim WJ, Wood AM, Barker AF, Brantly ML, Campbell EJ, Eden E, McElvaney G, Rennard SI, Sandhaus RA, Stocks JM, Stoller JK, Strange C, Turino G, Silverman EK, Stockley RA, et al. Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency. Respiratory Research. 13: 16. PMID 22356581 DOI: 10.1186/1465-9921-13-16  0.32
2012 Nakanishi M, Sato T, Li Y, Nelson AJ, Farid M, Michalski J, Kanaji N, Wang X, Basma H, Patil A, Goraya J, Liu X, Togo S, L Toews M, Holz O, ... ... Rennard SI, et al. Prostaglandin E2 stimulates the production of vascular endothelial growth factor through the E-prostanoid-2 receptor in cultured human lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 46: 217-23. PMID 22298530 DOI: 10.1165/rcmb.2010-0115OC  0.32
2012 Kanaji N, Nelson A, Allen-Gipson DS, Sato T, Nakanishi M, Wang X, Li Y, Basma H, Michalski J, Farid M, Rennard SI, Liu X. The p38 mitogen-activated protein kinases modulate endothelial cell survival and tissue repair. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 61: 233-44. PMID 22138711 DOI: 10.1007/s00011-011-0405-7  0.48
2011 Kanaji N, Sato T, Nelson A, Wang X, Li Y, Kim M, Nakanishi M, Basma H, Michalski J, Farid M, Chandler M, Pease W, Patil A, Rennard SI, Liu X. Inflammatory cytokines regulate endothelial cell survival and tissue repair functions via NF-κB signaling. Journal of Inflammation Research. 4: 127-38. PMID 22096375 DOI: 10.2147/JIR.S19461  0.48
2011 Vestbo J, Edwards LD, Scanlon PD, Yates JC, Agusti A, Bakke P, Calverley PM, Celli B, Coxson HO, Crim C, Lomas DA, MacNee W, Miller BE, Silverman EK, Tal-Singer R, ... ... Rennard SI, et al. Changes in forced expiratory volume in 1 second over time in COPD. The New England Journal of Medicine. 365: 1184-92. PMID 21991892 DOI: 10.1056/NEJMoa1105482  0.32
2011 Hughes JR, Russ CI, Arteaga CE, Rennard SI. Efficacy of a flexible quit date versus an a priori quit date approach to smoking cessation: a cross-study analysis. Addictive Behaviors. 36: 1288-91. PMID 21872998 DOI: 10.1016/j.addbeh.2011.08.001  0.32
2011 Siedlinski M, Cho MH, Bakke P, Gulsvik A, Lomas DA, Anderson W, Kong X, Rennard SI, Beaty TH, Hokanson JE, Crapo JD, Silverman EK, Coxson H, Edwards L, Knobil K, et al. Genome-wide association study of smoking behaviours in patients with COPD Thorax. 66: 894-902. PMID 21685187 DOI: 10.1136/thoraxjnl-2011-200154  0.32
2011 Hughes JR, Rennard SI, Fingar JR, Talbot SK, Callas PW, Fagerstrom KO. Efficacy of varenicline to prompt quit attempts in smokers not currently trying to quit: a randomized placebo-controlled trial. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 13: 955-64. PMID 21652735 DOI: 10.1093/ntr/ntr103  0.32
2011 Jones PW, Rennard SI, Agusti A, Chanez P, Magnussen H, Fabbri L, Donohue JF, Bateman ED, Gross NJ, Lamarca R, Caracta C, Gil EG. Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease. Respiratory Research. 12: 55. PMID 21518460 DOI: 10.1186/1465-9921-12-55  0.32
2011 Ding J, Yannam GR, Roy-Chowdhury N, Hidvegi T, Basma H, Rennard SI, Wong RJ, Avsar Y, Guha C, Perlmutter DH, Fox IJ, Roy-Chowdhury J. Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes. The Journal of Clinical Investigation. 121: 1930-4. PMID 21505264 DOI: 10.1172/JCI45260  0.32
2011 Sato T, Liu X, Basma H, Togo S, Sugiura H, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Michalski J, Farid M, Sharp JG, Rennard SI. IL-4 induces differentiation of human embryonic stem cells into fibrogenic fibroblast-like cells. The Journal of Allergy and Clinical Immunology. 127: 1595-603.e9. PMID 21388667 DOI: 10.1016/j.jaci.2011.01.049  0.48
2011 MacNee W, Rennard SI, Hunt JF, Edwards LD, Miller BE, Locantore NW, Tal-Singer R. Evaluation of exhaled breath condensate pH as a biomarker for COPD Respiratory Medicine. 105: 1037-1045. PMID 21377342 DOI: 10.1016/j.rmed.2011.02.009  0.32
2011 Togo S, Sato T, Sugiura H, Wang X, Basma H, Nelson A, Liu X, Bargar TW, Sharp JG, Rennard SI. Differentiation of embryonic stem cells into fibroblast-like cells in three-dimensional type I collagen gel cultures. In Vitro Cellular & Developmental Biology. Animal. 47: 114-24. PMID 21107747 DOI: 10.1007/s11626-010-9367-2  0.48
2011 Hanania NA, Müllerova H, Locantore NW, Vestbo J, Watkins ML, Wouters EF, Rennard SI, Sharafkhaneh A. Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort. American Journal of Respiratory and Critical Care Medicine. 183: 604-11. PMID 20889909 DOI: 10.1164/rccm.201003-0472OC  0.32
2011 Yentes JM, Sayles H, Meza J, Mannino DM, Rennard SI, Stergiou N. Walking abnormalities are associated with COPD: An investigation of the NHANES III dataset. Respiratory Medicine. 105: 80-7. PMID 20615681 DOI: 10.1016/j.rmed.2010.06.007  0.32
2011 Li YJ, Wang XQ, Sato T, Kanaji N, Nakanishi M, Kim M, Michalski J, Nelson AJ, Sun JH, Farid M, Basma H, Patil A, Toews ML, Liu X, Rennard SI. Prostaglandin Eâ‚‚ inhibits human lung fibroblast chemotaxis through disparate actions on different E-prostanoid receptors. American Journal of Respiratory Cell and Molecular Biology. 44: 99-107. PMID 20203295 DOI: 10.1165/rcmb.2009-0163OC  0.32
2010 Togo S, Sugiura H, Nelson A, Kobayashi T, Wang X, Kamio K, Kawasaki S, Bitterman P, Rennard SI, Liu X. Hepatic growth factor (HGF) inhibits cigarette smoke extract induced apoptosis in human bronchial epithelial cells. Experimental Cell Research. 316: 3501-11. PMID 20850432 DOI: 10.1016/j.yexcr.2010.09.006  0.48
2010 Sørheim IC, Bakke P, Gulsvik A, Pillai SG, Johannessen A, Gaarder PI, Campbell EJ, Agustí A, Calverley PM, Donner CF, Make BJ, Rennard SI, Vestbo J, Wouters EF, Paré PD, et al. α₁-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest. 138: 1125-32. PMID 20595457 DOI: 10.1378/chest.10-0746  0.32
2010 Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, MacNee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, et al. Chronic obstructive pulmonary disease phenotypes: The future of COPD American Journal of Respiratory and Critical Care Medicine. 182: 598-604. PMID 20522794 DOI: 10.1164/rccm.200912-1843CC  0.32
2010 Sato T, Liu X, Nelson A, Nakanishi M, Kanaji N, Wang X, Kim M, Li Y, Sun J, Michalski J, Patil A, Basma H, Holz O, Magnussen H, Rennard SI. Reduced miR-146a increases prostaglandin E₂in chronic obstructive pulmonary disease fibroblasts. American Journal of Respiratory and Critical Care Medicine. 182: 1020-9. PMID 20522791 DOI: 10.1164/rccm.201001-0055OC  0.48
2010 Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, ... ... Rennard SI, et al. Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. American Journal of Respiratory and Critical Care Medicine. 182: 605-13. PMID 20463177 DOI: 10.1164/rccm.200910-1586OC  0.32
2010 Chandler MA, Rennard SI. Smoking cessation. Chest. 137: 428-35. PMID 20133289 DOI: 10.1378/chest.09-0124  0.32
2010 Simet SM, Sisson JH, Pavlik JA, Devasure JM, Boyer C, Liu X, Kawasaki S, Sharp JG, Rennard SI, Wyatt TA. Long-term cigarette smoke exposure in a mouse model of ciliated epithelial cell function. American Journal of Respiratory Cell and Molecular Biology. 43: 635-40. PMID 20042711 DOI: 10.1165/rcmb.2009-0297OC  0.32
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