Pier P. Pandolfi - Publications

Weill Cornell Medical College, New York, NY, United States 
Cell Biology, Genetics, Molecular Biology, Oncology

424 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, ... ... Pandolfi PP, et al. Author Correction: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nature Genetics. PMID 32884149 DOI: 10.1038/S41588-020-0701-7  0.666
2020 Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP. Author Correction: Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nature Genetics. PMID 32820258 DOI: 10.1038/S41588-020-0688-0  0.314
2020 Liu J, Peng Y, Shi L, Wan L, Inuzuka H, Long J, Guo J, Zhang J, Yuan M, Zhang S, Wang X, Gao J, Dai X, Furumoto S, Jia L, ... Pandolfi PP, et al. Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle. Cell Research. PMID 32669607 DOI: 10.1038/S41422-020-0372-Z  0.331
2020 Vitiello M, Evangelista M, Zhang Y, Salmena L, Pandolfi PP, Poliseno L. PTENP1 is a ceRNA for PTEN: it's CRISPR clear. Journal of Hematology & Oncology. 13: 73. PMID 32517731 DOI: 10.1186/S13045-020-00894-2  0.319
2020 Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C, Pandolfi PP. WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition. The New England Journal of Medicine. 382: 2103-2116. PMID 32459922 DOI: 10.1056/Nejmoa1914919  0.354
2020 Chen KQ, Tahara N, Anderson A, Kawakami H, Kawakami S, Nishinakamura R, Pandolfi PP, Kawakami Y. Development of the Proximal-Anterior Skeletal Elements in the Mouse Hindlimb Is Regulated by a Transcriptional and Signaling Network Controlled by . Genetics. PMID 32156750 DOI: 10.1534/Genetics.120.303069  0.326
2020 Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, ... ... Pandolfi PP, et al. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature Cell Biology. PMID 32015438 DOI: 10.1038/S41556-020-0463-6  0.342
2019 Mendez LM, Posey RR, Pandolfi PP. The Interplay Between the Genetic and Immune Landscapes of AML: Mechanisms and Implications for Risk Stratification and Therapy. Frontiers in Oncology. 9: 1162. PMID 31781488 DOI: 10.3389/Fonc.2019.01162  0.309
2019 Nachmani D, Bothmer AH, Grisendi S, Mele A, Bothmer D, Lee JD, Monteleone E, Cheng K, Zhang Y, Bester AC, Guzzetti A, Mitchell CA, Mendez LM, Pozdnyakova O, Sportoletti P, ... ... Pandolfi PP, et al. Germline NPM1 mutations lead to altered rRNA 2'-O-methylation and cause dyskeratosis congenita. Nature Genetics. PMID 31570891 DOI: 10.1038/S41588-019-0502-Z  0.306
2019 Lee YR, Pandolfi PP. PTEN Mouse Models of Cancer Initiation and Progression. Cold Spring Harbor Perspectives in Medicine. PMID 31570383 DOI: 10.1101/Cshperspect.A037283  0.424
2019 Nath D, Li X, Mondragon C, Post D, Chen M, White JR, Hryniewicz-Jankowska A, Caza T, Kuznetsov VA, Hehnly H, Jamaspishvili T, Berman DM, Zhang F, Kung SHY, Fazli L, ... ... Pandolfi PP, et al. Abi1 loss drives prostate tumorigenesis through activation of EMT and non-canonical WNT signaling. Cell Communication and Signaling : Ccs. 17: 120. PMID 31530281 DOI: 10.1186/S12964-019-0410-Y  0.353
2019 Janin M, Ortiz-Barahona V, de Moura MC, Martínez-Cardús A, Llinàs-Arias P, Soler M, Nachmani D, Pelletier J, Schumann U, Calleja-Cervantes ME, Moran S, Guil S, Bueno-Costa A, Piñeyro D, Perez-Salvia M, ... ... Pandolfi PP, et al. Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program. Acta Neuropathologica. PMID 31428936 DOI: 10.1007/S00401-019-02062-4  0.314
2019 Han T, Jiang S, Zheng H, Yin Q, Xie M, Little MR, Yin X, Chen M, Song SJ, Beg AA, Pandolfi PP, Wan L. Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nature Communications. 10: 3716. PMID 31420536 DOI: 10.1038/S41467-019-11618-7  0.392
2019 Zhang J, Lee YR, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discovery. PMID 31217297 DOI: 10.1158/2159-8290.Cd-18-0083  0.331
2019 Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, ... ... Pandolfi PP, et al. Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science (New York, N.Y.). 364. PMID 31097636 DOI: 10.1126/Science.Aau0159  0.392
2019 Mugoni V, Panella R, Cheloni G, Chen M, Pozdnyakova O, Stroopinsky D, Guarnerio J, Monteleone E, Lee JD, Mendez L, Menon AV, Aster JC, Lane AA, Stone RM, Galinsky I, ... ... Pandolfi PP, et al. Vulnerabilities in mIDH2 AML confer sensitivity to APL-like targeted combination therapy. Cell Research. PMID 31024166 DOI: 10.1038/S41422-019-0162-7  0.313
2019 Papa A, Pandolfi PP. The PTEN⁻PI3K Axis in Cancer. Biomolecules. 9. PMID 30999672 DOI: 10.3390/biom9040153  0.3
2019 Vahabi M, Pulito C, Sacconi A, Donzelli S, D'Andrea M, Manciocco V, Pellini R, Paci P, Sanguineti G, Strigari L, Spriano G, Muti P, Pandolfi PP, Strano S, Safarian S, et al. miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells. Journal of Experimental & Clinical Cancer Research : Cr. 38: 141. PMID 30925916 DOI: 10.1186/S13046-019-1119-X  0.318
2019 Park MK, Yao Y, Xia W, Setijono SR, Kim JH, Vila IK, Chiu HH, Wu Y, Billalabeitia EG, Lee MG, Kalb RG, Hung MC, Pandolfi PP, Song SJ, Song MS. PTEN self-regulates through USP11 via the PI3K-FOXO pathway to stabilize tumor suppression. Nature Communications. 10: 636. PMID 30733438 DOI: 10.1038/S41467-019-08481-X  0.405
2019 Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, Guo A, Yuan M, Liu P, Asara JM, Toker A, Shi Y, Pandolfi PP, Wei W. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nature Cell Biology. PMID 30692625 DOI: 10.1038/S41556-018-0261-6  0.358
2018 Zhang J, Chen M, Zhu Y, Dai X, Dang F, Ren J, Ren S, Shulga YV, Beca F, Gan W, Wu F, Lin YM, Zhou X, DeCaprio JA, Beck AH, ... ... Pandolfi PP, et al. SPOP Promotes Nanog Destruction to Suppress Stem Cell Traits and Prostate Cancer Progression. Developmental Cell. PMID 30595538 DOI: 10.1016/J.Devcel.2018.11.035  0.412
2018 Chen M, Zhang J, Berger AH, Diolombi MS, Ng C, Fung J, Bronson RT, Castillo-Martin M, Thin TH, Cordon-Cardo C, Plevin R, Pandolfi PP. Compound haploinsufficiency of Dok2 and Dusp4 promotes lung tumorigenesis. The Journal of Clinical Investigation. PMID 30475228 DOI: 10.1172/Jci99699  0.671
2018 Molloy ME, Lewinska M, Williamson AK, Nguyen TT, Kuser-Abali G, Gong L, Yan J, Little JB, Pandolfi PP, Yuan ZM. ZBTB7A governs estrogen receptor alpha expression in breast cancer. Journal of Molecular Cell Biology. 10: 273-284. PMID 30265334 DOI: 10.1093/Jmcb/Mjy020  0.318
2018 Zhang W, Zhao C, Zhao J, Zhu Y, Weng X, Chen Q, Sun H, Mi JQ, Li J, Zhu J, Chen Z, Pandolfi PP, Chen S, Yan X, Xu J. Inactivation of PBX3 and HOXA9 by down-regulating H3K79 methylation represses NPM1-mutated leukemic cell survival. Theranostics. 8: 4359-4371. PMID 30214626 DOI: 10.7150/Thno.26900  0.376
2018 Currall BB, Chen M, Sallari RC, Cotter M, Wong KE, Robertson NG, Penney KL, Lunardi A, Reschke M, Hickox AE, Yin Y, Wong GT, Fung J, Brown KK, Williamson RE, ... ... Pandolfi PP, et al. Loss of LDAH associated with prostate cancer and hearing loss. Human Molecular Genetics. PMID 30169630 DOI: 10.1093/Hmg/Ddy310  0.315
2018 Lee YR, Chen M, Pandolfi PP. The functions and regulation of the PTEN tumour suppressor: new modes and prospects. Nature Reviews. Molecular Cell Biology. PMID 29858604 DOI: 10.1038/S41580-018-0015-0  0.386
2018 Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP. An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. Cell. 173: 649-664.e20. PMID 29677511 DOI: 10.1016/J.Cell.2018.03.052  0.354
2018 Ding M, van der Kwast TH, Vellanki RN, Foltz WD, McKee TD, Sonenberg N, Pandolfi PP, Koritzinsky M, Wouters BG. The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer. Molecular Cancer Research : McR. PMID 29453322 DOI: 10.1158/1541-7786.Mcr-17-0696  0.38
2018 Chen M, Zhang J, Sampieri K, Clohessy JG, Mendez L, Gonzalez-Billalabeitia E, Liu XS, Lee YR, Fung J, Katon JM, Menon AV, Webster KA, Ng C, Palumbieri MD, Diolombi MS, ... ... Pandolfi PP, et al. An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. Nature Genetics. PMID 29335545 DOI: 10.1038/S41588-017-0027-2  0.364
2018 Chen M, Wan L, Zhang J, Zhang J, Mendez L, Clohessy JG, Berry K, Victor J, Yin Q, Zhu Y, Wei W, Pandolfi PP. Deregulated PP1α phosphatase activity towards MAPK activation is antagonized by a tumor suppressive failsafe mechanism. Nature Communications. 9: 159. PMID 29335436 DOI: 10.1038/S41467-017-02272-Y  0.408
2018 Bezzi M, Seitzer N, Ishikawa T, Reschke M, Chen M, Wang G, Mitchell C, Ng C, Katon J, Lunardi A, Signoretti S, Clohessy JG, Zhang J, Pandolfi PP. Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms. Nature Medicine. PMID 29309058 DOI: 10.1038/Nm.4463  0.702
2018 Guarnerio J, Mendez LM, Asada N, Menon AV, Fung J, Berry K, Frenette PS, Ito K, Pandolfi PP. A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche. Nature Communications. 9: 66. PMID 29302031 DOI: 10.1038/S41467-017-02427-X  0.348
2018 Carrà G, Panuzzo C, Torti D, Parvis G, Crivellaro S, Familiari U, Volante M, Morena D, Lingua MF, Brancaccio M, Guerrasio A, Pandolfi PP, Saglio G, Taulli R, Morotti A. Therapeutic inhibition of USP7-PTEN network in chronic lymphocytic leukemia: a strategy to overcome TP53 mutated/deleted clones. Oncotarget. 8: 35508-35522. PMID 28418900 DOI: 10.18632/Oncotarget.16348  0.384
2018 Noguera NI, Piredda ML, Taulli R, Catalano G, Angelini G, Gaur G, Nervi C, Voso MT, Lunardi A, Pandolfi PP, Lo-Coco F. PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity. Oncotarget. 7: 66386-66397. PMID 27626703 DOI: 10.18632/Oncotarget.11964  0.403
2017 de Thé H, Pandolfi PP, Chen Z. Acute Promyelocytic Leukemia: A Paradigm for Oncoprotein-Targeted Cure. Cancer Cell. 32: 552-560. PMID 29136503 DOI: 10.1016/J.Ccell.2017.10.002  0.311
2017 Chen M, Pandolfi PP. Preclinical and Coclinical Studies in Prostate Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 29038335 DOI: 10.1101/Cshperspect.A030544  0.305
2017 Zarringhalam K, Tay Y, Kulkarni P, Bester AC, Pandolfi PP, Kulkarni RV. Identification of competing endogenous RNAs of the tumor suppressor gene PTEN: A probabilistic approach. Scientific Reports. 7: 7755. PMID 28798471 DOI: 10.1038/S41598-017-08209-1  0.314
2017 Tripodo C, Burocchi A, Piccaluga PP, Chiodoni C, Portararo P, Cappetti B, Botti L, Gulino A, Isidori A, Liso A, Visani G, Martelli MP, Falini B, Pandolfi PP, Colombo MP, et al. Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling. Cancer Research. 77: 3685-3699. PMID 28536276 DOI: 10.1158/0008-5472.Can-17-1098  0.328
2017 van de Ven AL, Tangutoori S, Baldwin P, Qiao J, Gharagouzloo C, Seitzer N, Clohessy JG, Makrigiorgos GM, Cormack R, Pandolfi PP, Sridhar S. Nanoformulation of Olaparib amplifies PARP inhibition and sensitizes PTEN/TP53-deficient prostate cancer to radiation. Molecular Cancer Therapeutics. PMID 28500233 DOI: 10.1158/1535-7163.Mct-16-0740  0.311
2017 Esteller M, Pandolfi PP. The Epitranscriptome of Noncoding RNAs in Cancer. Cancer Discovery. PMID 28320778 DOI: 10.1158/2159-8290.Cd-16-1292  0.352
2017 Patnaik A, Swanson KD, Csizmadia E, Solanki A, Landon-Brace N, Gehring MP, Helenius K, Olson BM, Pyzer AR, Wang LC, Elemento O, Novak J, Thornley TB, Asara JM, Montaser L, ... ... Pandolfi PP, et al. Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Anti-Tumor Innate Immunity. Cancer Discovery. PMID 28274958 DOI: 10.1158/2159-8290.Cd-16-0778  0.397
2017 Pyzer AR, Stroopinsky D, Rajabi H, Washington A, Tagde A, Coll M, Fung J, Bryant MP, Cole L, Palmer K, Somaiya P, Leaf RK, Nahas M, Apel A, Jain S, ... ... Pandolfi PP, et al. MUC1 mediated induction of myeloid-derived suppressor cells in patients with acute myeloid leukemia. Blood. PMID 28126925 DOI: 10.1182/Blood-2016-07-730614  0.391
2017 Ven ALvd, Tangutoori S, Baldwin P, Qiao J, Gharagouzloo C, Seitzer N, Clohessy J, Korideck H, Makrigiorgos GM, Cormack R, Pandolfi PP, Sridhar S. Abstract B48: Prostate cancer pre-treatment with nanoformulated Olaparib overcomes radiation resistance Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-B48  0.323
2016 Fagoonee S, Picco G, Orso F, Arrigoni A, Longo DL, Forni M, Scarfò I, Cassenti A, Piva R, Cassoni P, Silengo L, Tolosano E, Aime S, Taverna D, Pandolfi PP, et al. The RNA-binding protein ESRP1 promotes human colorectal cancer progression. Oncotarget. PMID 28052020 DOI: 10.18632/Oncotarget.14318  0.407
2016 Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, Saghatelian A, Nakayama KI, Clohessy JG, Pandolfi PP. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. PMID 28024296 DOI: 10.1038/Nature21034  0.333
2016 Davidson D, Zhong MC, Pandolfi PP, Bolland S, Xavier RJ, Seed B, Li X, Gu H, Veillette A. The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors. Cell Reports. 17: 2776-2788. PMID 27926878 DOI: 10.1016/J.Celrep.2016.11.035  0.33
2016 Lo Sardo F, Forcato M, Sacconi A, Capaci V, Zanconato F, Di Agostino S, Del Sal G, Pandolfi PP, Strano S, Bicciato S, Blandino G. MCM7 and its hosted miR-25, 93 and 106b cluster elicit YAP/TAZ oncogenic activity in lung cancer. Carcinogenesis. 38: 64-75. PMID 27797825 DOI: 10.1093/Carcin/Bgw110  0.399
2016 Shukla-Dave A, Castillo-Martin M, Chen M, Lobo J, Gladoun N, Lorduy AC, Khan FM, Ponomarev V, Yi Z, Zhang W, Pandolfi PP, Hricak H, Cordon-Cardo C. Ornithine Decarboxylase Is Sufficient for Prostate Tumorigenesis via Androgen Receptor Signaling. The American Journal of Pathology. PMID 27770613 DOI: 10.1016/J.Ajpath.2016.08.021  0.347
2016 German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, et al. PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2. Molecular Cell. 63: 1006-1020. PMID 27635760 DOI: 10.1016/J.Molcel.2016.08.014  0.357
2016 Missiroli S, Bonora M, Patergnani S, Poletti F, Perrone M, Gafà R, Magri E, Raimondi A, Lanza G, Tacchetti C, Kroemer G, Pandolfi PP, Pinton P, Giorgi C. PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development. Cell Reports. 16: 2415-27. PMID 27545895 DOI: 10.1016/J.Celrep.2016.07.082  0.389
2016 Guarnerio J, Bezzi M, Jeong JC, Paffenholz SV, Berry K, Naldini MM, Lo-Coco F, Tay Y, Beck AH, Pandolfi PP. Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations. Cell. 166: 1055-1056. PMID 27518567 DOI: 10.1016/J.Cell.2016.07.035  0.313
2016 Coppin E, De Grandis M, Pandolfi PP, Arcangeli ML, Aurrand-Lions M, Nunès JA. Dok1 and Dok2 Proteins Regulate Cell Cycle in Hematopoietic Stem and Progenitor Cells. Journal of Immunology (Baltimore, Md. : 1950). 196: 4110-21. PMID 27183638 DOI: 10.4049/Jimmunol.1501037  0.374
2016 Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, ... Pandolfi PP, et al. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Molecular Cell. 62: 34-46. PMID 27058786 DOI: 10.1016/J.Molcel.2016.03.013  0.425
2016 Guarnerio J, Bezzi M, Jeong JC, Paffenholz SV, Berry K, Naldini MM, Lo-Coco F, Tay Y, Beck AH, Pandolfi PP. Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations. Cell. PMID 27040497 DOI: 10.1016/J.Cell.2016.03.020  0.376
2016 Papa A, Pandolfi PP. Modeling Cancer-Associated Mutations of PTEN in Mice. Methods in Molecular Biology (Clifton, N.J.). 1388: 289-306. PMID 27033081 DOI: 10.1007/978-1-4939-3299-3_16  0.339
2016 Tay Y, Pandolfi PP. Posttranscriptional Regulation of PTEN by Competing Endogenous RNAs. Methods in Molecular Biology (Clifton, N.J.). 1388: 139-54. PMID 27033075 DOI: 10.1007/978-1-4939-3299-3_10  0.346
2016 Nemeth Z, Csizmadia E, Vikstrom L, Li M, Bisht K, Feizi A, Otterbein S, Zuckerbraun B, Costa DB, Pandolfi PP, Fillinger J, Döme B, Otterbein LE, Wegiel B. Alterations of tumor microenvironment by carbon monoxide impedes lung cancer growth. Oncotarget. PMID 26993595 DOI: 10.18632/Oncotarget.8081  0.369
2016 Niki M, Nayak MK, Jin H, Bhasin N, Plow EF, Pandolfi PP, Rothman PB, Chauhan AK, Lentz SR. Dok-1 negatively regulates platelet integrin αIIbβ3 outside-in signalling and inhibits thrombosis in mice. Thrombosis and Haemostasis. 115. PMID 26790499 DOI: 10.1160/Th15-05-0373  0.302
2016 Patnaik A, Swanson KD, Csizmadia E, Gehring MP, Helenius K, Pyzer AR, Wang LC, Novak J, Elemento O, Thornley TB, Asara JM, Clohessy JG, Kelly K, Pandolfi PP, Rosenblatt JM, et al. Abstract 4979: Cabozantinib eradicates advanced murine prostate cancer by activating neutrophil-mediated anti-tumor innate immunity Cancer Research. 76: 4979-4979. DOI: 10.1158/1538-7445.Am2016-4979  0.395
2016 Carrà G, Panuzzo C, Torti D, Parvis G, Crivellaro S, Volante M, Morena D, Lingua M, Brancaccio M, Guerrasio A, Pandolfi PP, Saglio G, Taulli R, Morotti A. Inhibition OF USP7 Induces Selective Cancer Cell Death in Chronic Lymphocytic Leukemia Clinical Lymphoma, Myeloma & Leukemia. 16: 49-50. DOI: 10.1016/J.Clml.2016.07.071  0.331
2015 Chew CL, Chen M, Pandolfi PP. Endosome and INPP4B. Oncotarget. PMID 26700619 DOI: 10.18632/Oncotarget.6663  0.459
2015 Duquette M, Sadow PM, Husain A, Sims JN, Antonello ZA, Fischer AH, Song C, Castellanos-Rizaldos E, Makrigiorgos GM, Kurebayashi J, Nose V, Van Hummelen P, Bronson RT, Vinco M, Giordano TJ, ... ... Pandolfi PP, et al. Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model. Oncotarget. PMID 26636651 DOI: 10.18632/Oncotarget.6442  0.376
2015 Gaublomme JT, Yosef N, Lee Y, Gertner RS, Yang LV, Wu C, Pandolfi PP, Mak T, Satija R, Shalek AK, Kuchroo VK, Park H, Regev A. Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity. Cell. PMID 26607794 DOI: 10.1016/J.Cell.2015.11.009  0.33
2015 Liu XS, Chandramouly G, Rass E, Guan Y, Wang G, Hobbs RM, Rajendran A, Xie A, Shah JV, Davis AJ, Scully R, Lunardi A, Pandolfi PP. LRF maintains genome integrity by regulating the non-homologous end joining pathway of DNA repair. Nature Communications. 6: 8325. PMID 26446488 DOI: 10.1038/Ncomms9325  0.696
2015 Poliseno L, Marranci A, Pandolfi PP. Pseudogenes in Human Cancer. Frontiers in Medicine. 2: 68. PMID 26442270 DOI: 10.3389/Fmed.2015.00068  0.337
2015 Gan W, Dai X, Lunardi A, Li Z, Inuzuka H, Liu P, Varmeh S, Zhang J, Cheng L, Sun Y, Asara JM, Beck AH, Huang J, Pandolfi PP, Wei W. SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression. Molecular Cell. PMID 26344095 DOI: 10.1016/J.Molcel.2015.07.026  0.381
2015 Heinrich F, Chakravarthy S, Nanda H, Papa A, Pandolfi PP, Ross AH, Harishchandra RK, Gericke A, Lösche M. The PTEN Tumor Suppressor Forms Homodimers in Solution. Structure (London, England : 1993). 23: 1952-7. PMID 26299948 DOI: 10.1016/J.Str.2015.07.012  0.367
2015 Serra H, Chivite I, Angulo-Urarte A, Soler A, Sutherland JD, Arruabarrena-Aristorena A, Ragab A, Lim R, Malumbres M, Fruttiger M, Potente M, Serrano M, Fabra À, Viñals F, Casanovas O, ... Pandolfi PP, et al. PTEN mediates Notch-dependent stalk cell arrest in angiogenesis. Nature Communications. 6: 7935. PMID 26228240 DOI: 10.1038/Ncomms8935  0.362
2015 Luzzatto L, Pandolfi PP. Causality and Chance in the Development of Cancer. The New England Journal of Medicine. 373: 84-8. PMID 26132946 DOI: 10.1056/Nejmsb1502456  0.352
2015 Carracedo A, Rousseau D, Douris N, Fernández-Ruiz S, Martín-Martín N, Weiss D, Webster K, Adams AC, Vazquez-Chantada M, Martinez-Chantar ML, Anty R, Tran A, Maratos-Flier E, Gual P, Pandolfi PP. The promyelocytic leukemia protein is upregulated in conditions of obesity and liver steatosis. International Journal of Biological Sciences. 11: 629-32. PMID 25999785 DOI: 10.7150/Ijbs.11615  0.32
2015 Liu XS, Genet MD, Haines JE, Mehanna EK, Wu S, Chen HI, Chen Y, Qureshi AA, Han J, Chen X, Fisher DE, Pandolfi PP, Yuan ZM. ZBTB7A suppresses melanoma metastasis by transcriptionally repressing MCAM. Molecular Cancer Research : McR. PMID 25995384 DOI: 10.1158/1541-7786.Mcr-15-0169  0.376
2015 Sowalsky AG, Sager R, Schaefer RJ, Bratslavsky G, Pandolfi PP, Balk SP, Kotula L. Loss of Wave1 gene defines a subtype of lethal prostate cancer. Oncotarget. 6: 12383-91. PMID 25906751 DOI: 10.18632/Oncotarget.3564  0.34
2015 Clohessy JG, Pandolfi PP. Mouse hospital and co-clinical trial project--from bench to bedside. Nature Reviews. Clinical Oncology. 12: 491-8. PMID 25895610 DOI: 10.1038/Nrclinonc.2015.62  0.31
2015 Li Chew C, Lunardi A, Gulluni F, Ruan DT, Chen M, Salmena L, Nishino M, Papa A, Ng C, Fung J, Clohessy JG, Sasaki J, Sasaki T, Bronson RT, Hirsch E, ... Pandolfi PP, et al. In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes. Cancer Discovery. 5: 740-51. PMID 25883022 DOI: 10.1158/2159-8290.Cd-14-1347  0.417
2015 Wei S, Kozono S, Kats L, Nechama M, Li W, Guarnerio J, Luo M, You MH, Yao Y, Kondo A, Hu H, Bozkurt G, Moerke NJ, Cao S, Reschke M, ... ... Pandolfi PP, et al. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer. Nature Medicine. 21: 457-66. PMID 25849135 DOI: 10.1038/Nm.3839  0.42
2015 Karreth FA, Reschke M, Ruocco A, Ng C, Chapuy B, Léopold V, Sjoberg M, Keane TM, Verma A, Ala U, Tay Y, Wu D, Seitzer N, Velasco-Herrera Mdel C, Bothmer A, ... ... Pandolfi PP, et al. The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo. Cell. 161: 319-32. PMID 25843629 DOI: 10.1016/J.Cell.2015.02.043  0.396
2015 Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, Najafov A, Liu M, Li Y, Han X, Xiao J, Jin Z, Peng T, Gao Y, Cai Y, ... ... Pandolfi PP, et al. G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L. Elife. 4: e06734. PMID 25821988 DOI: 10.7554/Elife.06734  0.327
2015 Hobbs RM, La HM, Mäkelä JA, Kobayashi T, Noda T, Pandolfi PP. Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling. Embo Reports. 16: 467-80. PMID 25700280 DOI: 10.15252/Embr.201439379  0.338
2015 Di Savino A, Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, Carrà G, Ferretti R, Fusella F, Giugliano E, Camporeale A, Franco I, Miniscalco B, Cutrin JC, Turco E, ... ... Pandolfi PP, et al. Morgana acts as an oncosuppressor in chronic myeloid leukemia. Blood. 125: 2245-53. PMID 25678499 DOI: 10.1182/Blood-2014-05-575001  0.314
2015 Lunardi A, Varmeh S, Chen M, Taulli R, Guarnerio J, Ala U, Seitzer N, Ishikawa T, Carver BS, Hobbs RM, Quarantotti V, Ng C, Berger AH, Nardella C, Poliseno L, ... ... Pandolfi PP, et al. Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis. Cancer Discovery. 5: 550-63. PMID 25653093 DOI: 10.1158/2159-8290.Cd-13-1050  0.67
2015 Poliseno L, Pandolfi PP. PTEN ceRNA networks in human cancer. Methods (San Diego, Calif.). 41-50. PMID 25644446 DOI: 10.1016/J.Ymeth.2015.01.013  0.342
2015 Giorgi C, Bonora M, Sorrentino G, Missiroli S, Poletti F, Suski JM, Galindo Ramirez F, Rizzuto R, Di Virgilio F, Zito E, Pandolfi PP, Wieckowski MR, Mammano F, Del Sal G, Pinton P. p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 112: 1779-84. PMID 25624484 DOI: 10.1073/Pnas.1410723112  0.315
2015 Guarnerio J, Riccardi L, Taulli R, Maeda T, Wang G, Hobbs RM, Song MS, Sportoletti P, Bernardi R, Bronson RT, Castillo-Martin M, Cordon-Cardo C, Lunardi A, Pandolfi PP. A genetic platform to model sarcomagenesis from primary adult mesenchymal stem cells. Cancer Discovery. 5: 396-409. PMID 25614485 DOI: 10.1158/2159-8290.Cd-14-1022  0.692
2015 Epping MT, Lunardi A, Nachmani D, Castillo-Martin M, Thin TH, Cordon-Cardo C, Pandolfi PP. TSPYL2 is an essential component of the REST/NRSF transcriptional complex for TGFβ signaling activation. Cell Death and Differentiation. 22: 1353-62. PMID 25613376 DOI: 10.1038/Cdd.2014.226  0.432
2015 Morotti A, Panuzzo C, Crivellaro S, Carrà G, Fava C, Guerrasio A, Pandolfi PP, Saglio G. BCR-ABL inactivates cytosolic PTEN through Casein Kinase II mediated tail phosphorylation. Cell Cycle (Georgetown, Tex.). 14: 973-9. PMID 25608112 DOI: 10.1080/15384101.2015.1006970  0.41
2015 Briercheck EL, Trotta R, Chen L, Hartlage AS, Cole JP, Cole TD, Mao C, Banerjee PP, Hsu HT, Mace EM, Ciarlariello D, Mundy-Bosse BL, Garcia-Cao I, Scoville SD, Yu L, ... ... Pandolfi PP, et al. PTEN is a negative regulator of NK cell cytolytic function. Journal of Immunology (Baltimore, Md. : 1950). 194: 1832-40. PMID 25595786 DOI: 10.4049/Jimmunol.1401224  0.334
2015 Giorgi C, Bonora M, Missiroli S, Poletti F, Ramirez FG, Morciano G, Morganti C, Pandolfi PP, Mammano F, Pinton P. Intravital imaging reveals p53-dependent cancer cell death induced by phototherapy via calcium signaling. Oncotarget. 6: 1435-45. PMID 25544762 DOI: 10.18632/Oncotarget.2935  0.34
2015 Newton RH, Lu Y, Papa A, Whitcher GH, Kang YJ, Yan C, Pandolfi PP, Turka LA. Suppression of T-cell lymphomagenesis in mice requires PTEN phosphatase activity. Blood. 125: 852-5. PMID 25477498 DOI: 10.1182/Blood-2014-04-571372  0.348
2015 Coppin E, Gelsi-Boyer V, Morelli X, Cervera N, Murati A, Pandolfi PP, Birnbaum D, Nunès JA. Mutational analysis of the DOK2 haploinsufficient tumor suppressor gene in chronic myelomonocytic leukemia (CMML). Leukemia. 29: 500-2. PMID 25252871 DOI: 10.1038/Leu.2014.288  0.315
2015 Karreth FA, Ala U, Provero P, Pandolfi PP. Pseudogenes as competitive endogenous RNAs: target prediction and validation. Methods in Molecular Biology (Clifton, N.J.). 1167: 199-212. PMID 24823779 DOI: 10.1007/978-1-4939-0835-6_13  0.303
2015 Karreth FA, Reschke M, Bjoern C, Shipp M, Chiarle R, Pandolfi PP. Abstract A37: The BRAF pseudogene is a proto-oncogenic competitive endogenous RNA. Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Hemmal14-A37  0.414
2015 Pandolfi PP. Abstract IA15: New insights on the role of tumor suppressor phosphatases Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-Ia15  0.441
2015 Patnaik A, Swanson K, Signoretti S, Ye H, Csizmadia E, Novak J, Gehring M, Helenius K, Pyzer A, Montaser L, Wang L, Elemento O, Levantini E, Clohessy J, Asara J, ... ... Pandolfi PP, et al. Abstract C112: Cabozantinib eradicates advanced murine prostate cancer by activating anti-tumor innate immunity Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C112  0.396
2015 Carrà G, Panuzzo C, Torti D, Parvis G, Crivellaro S, Brancaccio M, Guerrasio A, Pandolfi PP, Saglio G, Morotti A. Therapeutic inhibition of HAUSP-PTEN network in chronic lymphocytic leukemia Clinical Lymphoma Myeloma and Leukemia. 15: S25. DOI: 10.1016/J.Clml.2015.07.055  0.331
2014 Lunardi A, Pandolfi PP. A co-clinical platform to accelerate cancer treatment optimization. Trends in Molecular Medicine. 21: 1-5. PMID 25466492 DOI: 10.1016/J.Molmed.2014.10.008  0.307
2014 Matsushita H, Yahata T, Sheng Y, Nakamura Y, Muguruma Y, Matsuzawa H, Tanaka M, Hayashi H, Sato T, Damdinsuren A, Onizuka M, Ito M, Miyachi H, Pandolfi PP, Ando K. Establishment of a humanized APL model via the transplantation of PML-RARA-transduced human common myeloid progenitors into immunodeficient mice. Plos One. 9: e111082. PMID 25369030 DOI: 10.1371/Journal.Pone.0111082  0.318
2014 Toso A, Revandkar A, Di Mitri D, Guccini I, Proietti M, Sarti M, Pinton S, Zhang J, Kalathur M, Civenni G, Jarrossay D, Montani E, Marini C, Garcia-Escudero R, Scanziani E, ... ... Pandolfi PP, et al. Enhancing chemotherapy efficacy in Pten-deficient prostate tumors by activating the senescence-associated antitumor immunity. Cell Reports. 9: 75-89. PMID 25263564 DOI: 10.1016/J.Celrep.2014.08.044  0.381
2014 Tay Y, Tan SM, Karreth FA, Lieberman J, Pandolfi PP. Characterization of dual PTEN and p53-targeting microRNAs identifies microRNA-638/Dnm2 as a two-hit oncogenic locus. Cell Reports. 8: 714-22. PMID 25088422 DOI: 10.1016/J.Celrep.2014.06.064  0.304
2014 Sadow PM, Priolo C, Nanni S, Karreth FA, Duquette M, Martinelli R, Husain A, Clohessy J, Kutzner H, Mentzel T, Carman CV, Farsetti A, Henske EP, Palescandolo E, Macconaill LE, ... ... Pandolfi PP, et al. Role of BRAFV600E in the first preclinical model of multifocal infiltrating myopericytoma development and microenvironment. Journal of the National Cancer Institute. 106. PMID 25063326 DOI: 10.1093/Jnci/Dju182  0.352
2014 Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, ... ... Pandolfi PP, et al. A unified nomenclature and amino acid numbering for human PTEN. Science Signaling. 7: pe15. PMID 24985344 DOI: 10.1126/Scisignal.2005560  0.33
2014 Celis-Gutierrez J, Boyron M, Walzer T, Pandolfi PP, Jonji? S, Olive D, Dalod M, Vivier E, Nunès JA. Dok1 and Dok2 proteins regulate natural killer cell development and function. The Embo Journal. 33: 1928-40. PMID 24963146 DOI: 10.15252/Embj.201387404  0.354
2014 Guarnerio J, Coltella N, Ala U, Tonon G, Pandolfi PP, Bernardi R. Bone marrow endosteal mesenchymal progenitors depend on HIF factors for maintenance and regulation of hematopoiesis. Stem Cell Reports. 2: 794-809. PMID 24936467 DOI: 10.1016/J.Stemcr.2014.04.002  0.326
2014 González-Billalabeitia E, Seitzer N, Song SJ, Song MS, Patnaik A, Liu XS, Epping MT, Papa A, Hobbs RM, Chen M, Lunardi A, Ng C, Webster KA, Signoretti S, Loda M, ... ... Pandolfi PP, et al. Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition. Cancer Discovery. 4: 896-904. PMID 24866151 DOI: 10.1158/2159-8290.Cd-13-0230  0.353
2014 Papa A, Wan L, Bonora M, Salmena L, Song MS, Hobbs RM, Lunardi A, Webster K, Ng C, Newton RH, Knoblauch N, Guarnerio J, Ito K, Turka LA, Beck AH, ... ... Pandolfi PP, et al. Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function. Cell. 157: 595-610. PMID 24766807 DOI: 10.1016/J.Cell.2014.03.027  0.408
2014 Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M, Lane AN, ... ... Pandolfi PP, et al. Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells. Cell Metabolism. 19: 795-809. PMID 24726384 DOI: 10.1016/J.Cmet.2014.03.003  0.402
2014 Coltella N, Percio S, Valsecchi R, Cuttano R, Guarnerio J, Ponzoni M, Pandolfi PP, Melillo G, Pattini L, Bernardi R. HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapse. Embo Molecular Medicine. 6: 640-50. PMID 24711541 DOI: 10.1002/Emmm.201303065  0.38
2014 Liu P, Begley M, Michowski W, Inuzuka H, Ginzberg M, Gao D, Tsou P, Gan W, Papa A, Kim BM, Wan L, Singh A, Zhai B, Yuan M, Wang Z, ... ... Pandolfi PP, et al. Cell-cycle-regulated activation of Akt kinase by phosphorylation at its carboxyl terminus. Nature. 508: 541-5. PMID 24670654 DOI: 10.1038/Nature13079  0.384
2014 Lunardi A, Webster KA, Papa A, Padmani B, Clohessy JG, Bronson RT, Pandolfi PP. Role of aberrant PI3K pathway activation in gallbladder tumorigenesis. Oncotarget. 5: 894-900. PMID 24658595 DOI: 10.18632/Oncotarget.1808  0.409
2014 Fusella F, Ferretti R, Recupero D, Rocca S, Di Savino A, Tornillo G, Silengo L, Turco E, Cabodi S, Provero P, Pandolfi PP, Sapino A, Tarone G, Brancaccio M. Morgana acts as a proto-oncogene through inhibition of a ROCK-PTEN pathway. The Journal of Pathology. 234: 152-63. PMID 24615293 DOI: 10.1002/Path.4341  0.389
2014 Tay Y, Karreth FA, Pandolfi PP. Aberrant ceRNA activity drives lung cancer. Cell Research. 24: 259-60. PMID 24525785 DOI: 10.1038/Cr.2014.21  0.341
2014 Kats LM, Reschke M, Taulli R, Pozdnyakova O, Burgess K, Bhargava P, Straley K, Karnik R, Meissner A, Small D, Su SM, Yen K, Zhang J, Pandolfi PP. Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance. Cell Stem Cell. 14: 329-41. PMID 24440599 DOI: 10.1016/J.Stem.2013.12.016  0.379
2014 Dowling JK, Becker CE, Bourke NM, Corr SC, Connolly DJ, Quinn SR, Pandolfi PP, Mansell A, O'Neill LA. Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation. The Journal of Biological Chemistry. 289: 6429-37. PMID 24407287 DOI: 10.1074/Jbc.M113.539692  0.301
2014 Lunardi A, Nardella C, Clohessy JG, Pandolfi PP. Of model pets and cancer models: an introduction to mouse models of cancer. Cold Spring Harbor Protocols. 2014: 17-31. PMID 24371312 DOI: 10.1101/Pdb.Top069757  0.322
2014 Bohn O, Maeda T, Filatov A, Lunardi A, Pandolfi PP, Teruya-Feldstein J. Utility of LRF/Pokemon and NOTCH1 protein expression in the distinction between nodular lymphocyte-predominant Hodgkin lymphoma and classical Hodgkin lymphoma. International Journal of Surgical Pathology. 22: 6-11. PMID 24326827 DOI: 10.1177/1066896913513833  0.339
2014 Morotti A, Panuzzo C, Crivellaro S, Pergolizzi B, Familiari U, Berger AH, Saglio G, Pandolfi PP. BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP. Leukemia. 28: 1326-33. PMID 24317448 DOI: 10.1038/Leu.2013.370  0.702
2014 Rau R, Magoon D, Greenblatt S, Li L, Annesley C, Duffield AS, Huso D, McIntyre E, Clohessy JG, Reschke M, Pandolfi PP, Small D, Brown P. NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease. Experimental Hematology. 42: 101-13.e5. PMID 24184354 DOI: 10.1016/J.Exphem.2013.10.005  0.326
2014 Saoncella S, Tassone B, Deklic E, Avolio F, Jon C, Tornillo G, De Luca E, Di Iorio E, Piva R, Cabodi S, Turco E, Pandolfi PP, Calautti E. Nuclear Akt2 opposes limbal keratinocyte stem cell self-renewal by repressing a FOXO-mTORC1 signaling pathway. Stem Cells (Dayton, Ohio). 32: 754-69. PMID 24123662 DOI: 10.1002/Stem.1565  0.367
2014 Karreth F, Reschke M, Chapuy B, Shipp MA, Chiarle R, Pandolfi PP. The BRAF Pseudogene Is a Proto-Oncogenic Competitive Endogenous RNA Blood. 124: 263-263. DOI: 10.1182/Blood.V124.21.263.263  0.408
2014 Gallardo M, Lee HJ, Zhang X, Pageon LR, Multani A, Reschke M, Clohessy JG, Quintás-Cardama A, Andreeff M, Kornblau SM, Pandolfi PP, Post SM. hnRNP K Overexpression Synergizes with Mutant NPM1 to Drive Acute Myeloid Leukemia Progression Blood. 124: 2382-2382. DOI: 10.1182/Blood.V124.21.2382.2382  0.325
2014 Matsushita H, Yahata T, Sheng Y, Nakamura Y, Muguruma Y, Matsuzawa H, Tanaka M, Hayashi H, Sato T, Damdinsuren A, Onizuka M, Ito M, Miyachi H, Pandolfi PP, Ando K. In Vivo Analysis of PML-RARA in a Humanized Mouse Model Blood. 124: 1020-1020. DOI: 10.1182/Blood.V124.21.1020.1020  0.315
2014 Pandolfi PP. Abstract IA3: The Co-Clinical Trial Project Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Ia3  0.378
2014 Chorzalska A, Xiong X, Lunardi A, White JR, Sawicki JA, Bratslavsky G, Pandolfi PP, Kotula L. Abstract B06: Abi1 levels regulate prostate tumor progression in mice downstream from Pten inactivation Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B06  0.403
2014 Guarnerio J, Lunardi A, Pandolfi PP. Abstract 601: Essential role of LRF in mesenchymal stem cell differentiation and tumorigenesis through Dlk1 and Sox9 repression Cancer Research. 74: 601-601. DOI: 10.1158/1538-7445.Am2014-601  0.393
2014 Berns A, Pandolfi PP. Tumor microenvironment revisited Embo Reports. 15: 458-459. DOI: 10.1002/Embr.201438794  0.333
2013 Dos Santos GA, Kats L, Pandolfi PP. Synergy against PML-RARa: targeting transcription, proteolysis, differentiation, and self-renewal in acute promyelocytic leukemia. The Journal of Experimental Medicine. 210: 2793-802. PMID 24344243 DOI: 10.1084/Jem.20131121  0.385
2013 Berger AH, Chen M, Morotti A, Janas JA, Niki M, Bronson RT, Taylor BS, Ladanyi M, Van Aelst L, Politi K, Varmus HE, Pandolfi PP. DOK2 inhibits EGFR-mutated lung adenocarcinoma. Plos One. 8: e79526. PMID 24255704 DOI: 10.1371/Journal.Pone.0079526  0.641
2013 Abate-Shen C, Pandolfi PP. Effective utilization and appropriate selection of genetically engineered mouse models for translational integration of mouse and human trials. Cold Spring Harbor Protocols. 2013. PMID 24173311 DOI: 10.1101/Pdb.Top078774  0.309
2013 Wegiel B, Gallo D, Csizmadia E, Harris C, Belcher J, Vercellotti GM, Penacho N, Seth P, Sukhatme V, Ahmed A, Pandolfi PP, Helczynski L, Bjartell A, Persson JL, Otterbein LE. Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth. Cancer Research. 73: 7009-21. PMID 24121491 DOI: 10.1158/0008-5472.Can-13-1075  0.394
2013 Fagoonee S, Bearzi C, Di Cunto F, Clohessy JG, Rizzi R, Reschke M, Tolosano E, Provero P, Pandolfi PP, Silengo L, Altruda F. The RNA binding protein ESRP1 fine-tunes the expression of pluripotency-related factors in mouse embryonic stem cells. Plos One. 8: e72300. PMID 24015231 DOI: 10.1371/Journal.Pone.0072300  0.335
2013 Fausti F, Di Agostino S, Cioce M, Bielli P, Sette C, Pandolfi PP, Oren M, Sudol M, Strano S, Blandino G. ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence. Cell Death and Differentiation. 20: 1498-509. PMID 23933816 DOI: 10.1038/Cdd.2013.101  0.392
2013 Papa A, Chen M, Pandolfi PP. Pills of PTEN? In and out for tumor suppression. Cell Research. 23: 1155-6. PMID 23917528 DOI: 10.1038/Cr.2013.103  0.35
2013 Stroopinsky D, Rosenblatt J, Ito K, Mills H, Yin L, Rajabi H, Vasir B, Kufe T, Luptakova K, Arnason J, Nardella C, Levine JD, Joyce RM, Galinsky I, Reiter Y, ... ... Pandolfi PP, et al. MUC1 is a potential target for the treatment of acute myeloid leukemia stem cells. Cancer Research. 73: 5569-79. PMID 23867470 DOI: 10.1158/0008-5472.Can-13-0677  0.332
2013 Bononi A, Bonora M, Marchi S, Missiroli S, Poletti F, Giorgi C, Pandolfi PP, Pinton P. Identification of PTEN at the ER and MAMs and its regulation of Ca(2+) signaling and apoptosis in a protein phosphatase-dependent manner. Cell Death and Differentiation. 20: 1631-43. PMID 23811847 DOI: 10.1038/Cdd.2013.77  0.31
2013 Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA, Tay Y, Gonzalez-Billalabeitia E, Egia A, Shaffer DR, Carver B, Liu XS, Taulli R, Kuo WP, Nardella C, ... ... Pandolfi PP, et al. Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion. Nature Genetics. 45: 739-46. PMID 23727861 DOI: 10.1038/Ng.2654  0.712
2013 Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, ... ... Pandolfi PP, et al. A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer. Nature Genetics. 45: 747-55. PMID 23727860 DOI: 10.1038/Ng.2650  0.693
2013 Guijarro MV, Dahiya S, Danielson LS, Segura MF, Vales-Lara FM, Menendez S, Popiolek D, Mittal K, Wei JJ, Zavadil J, Cordon-Cardo C, Pandolfi PP, Hernando E. Dual Pten/Tp53 suppression promotes sarcoma progression by activating Notch signaling. The American Journal of Pathology. 182: 2015-27. PMID 23708211 DOI: 10.1016/J.Ajpath.2013.02.035  0.403
2013 Haupt S, Mitchell C, Corneille V, Shortt J, Fox S, Pandolfi PP, Castillo-Martin M, Bonal DM, Cordon-Cardo C, Lozano G, Haupt Y. Loss of PML cooperates with mutant p53 to drive more aggressive cancers in a gender-dependent manner. Cell Cycle (Georgetown, Tex.). 12: 1722-31. PMID 23656786 DOI: 10.4161/Cc.24805  0.412
2013 Carracedo A, Cantley LC, Pandolfi PP. Cancer metabolism: fatty acid oxidation in the limelight. Nature Reviews. Cancer. 13: 227-32. PMID 23446547 DOI: 10.1038/Nrc3483  0.319
2013 Nguyen AH, Tremblay M, Haigh K, Koumakpayi IH, Paquet M, Pandolfi PP, Mes-Masson AM, Saad F, Haigh JJ, Bouchard M. Gata3 antagonizes cancer progression in Pten-deficient prostates. Human Molecular Genetics. 22: 2400-10. PMID 23428429 DOI: 10.1093/Hmg/Ddt088  0.375
2013 Lunardi A, Guarnerio J, Wang G, Maeda T, Pandolfi PP. Role of LRF/Pokemon in lineage fate decisions. Blood. 121: 2845-53. PMID 23396304 DOI: 10.1182/Blood-2012-11-292037  0.677
2013 Noguera NI, Song MS, Divona M, Catalano G, Calvo KL, García F, Ottone T, Florenzano F, Faraoni I, Battistini L, Colombo E, Amadori S, Pandolfi PP, Lo-Coco F. Nucleophosmin/B26 regulates PTEN through interaction with HAUSP in acute myeloid leukemia. Leukemia. 27: 1037-43. PMID 23183427 DOI: 10.1038/Leu.2012.314  0.342
2013 Stroopinsky D, Rajabi H, Rosenblatt J, Mills H, Kufe T, Luptakova K, Vasir B, Coll MD, Kristen P, Kharbanda A, Neeharika S, Joyce R, Levine JD, Arnason J, Stone RM, ... Pandolfi PP, et al. MUC1 Expression Is Essential For Establishment Of Acute Myeloid Leukemia In Vivo Blood. 122: 3787-3787. DOI: 10.1182/Blood.V122.21.3787.3787  0.39
2013 Pandolfi PP. Abstract IA12: The noncoding RNA revolution in cancer research Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia12  0.305
2012 Papa A, Cordon-Cardo C, Bernardi R, Pandolfi PP. Compound In Vivo Inactivation of Pml and p53 Uncovers a Functional Interaction in Angiosarcoma Suppression. Genes & Cancer. 3: 599-603. PMID 23486996 DOI: 10.1177/1947601912473604  0.404
2012 Liu Y, Liu F, Yu H, Zhao X, Sashida G, Deblasio A, Harr M, She QB, Chen Z, Lin HK, Di Giandomenico S, Elf SE, Yang Y, Miyata Y, Huang G, ... ... Pandolfi PP, et al. Akt phosphorylates the transcriptional repressor Bmi1 to block its effects on the tumor-suppressing Ink4a-Arf locus Science Signaling. 5. PMID 23092893 DOI: 10.1126/Scisignal.2003199  0.418
2012 Syed F, Sherris D, Paus R, Varmeh S, Singh S, Pandolfi PP, Bayat A. Keloid disease can be inhibited by antagonizing excessive mTOR signaling with a novel dual TORC1/2 inhibitor. The American Journal of Pathology. 181: 1642-58. PMID 22982188 DOI: 10.1016/J.Ajpath.2012.08.006  0.356
2012 Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmañà J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, et al. Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer. Cancer Discovery. 2: 1048-63. PMID 22915751 DOI: 10.1158/2159-8290.Cd-11-0336  0.372
2012 Ito K, Carracedo A, Weiss D, Arai F, Ala U, Avigan DE, Schafer ZT, Evans RM, Suda T, Lee CH, Pandolfi PP. A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nature Medicine. 18: 1350-8. PMID 22902876 DOI: 10.1038/Nm.2882  0.352
2012 Carracedo A, Weiss D, Leliaert AK, Bhasin M, de Boer VC, Laurent G, Adams AC, Sundvall M, Song SJ, Ito K, Finley LS, Egia A, Libermann T, Gerhart-Hines Z, Puigserver P, ... ... Pandolfi PP, et al. A metabolic prosurvival role for PML in breast cancer. The Journal of Clinical Investigation. 122: 3088-100. PMID 22886304 DOI: 10.1172/Jci62129  0.342
2012 Khanna-Gupta A, Abayasekara N, Levine M, Sun H, Virgilio M, Nia N, Halene S, Sportoletti P, Jeong JY, Pandolfi PP, Berliner N. Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein α activity: implications in myelodysplastic syndrome and acute myeloid leukemia. The Journal of Biological Chemistry. 287: 32728-37. PMID 22851180 DOI: 10.1074/Jbc.M112.373274  0.37
2012 Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, ... ... Pandolfi PP, et al. Acetylation-dependent regulation of Skp2 function. Cell. 150: 179-93. PMID 22770219 DOI: 10.1016/J.Cell.2012.05.038  0.396
2012 Taulli R, Pandolfi PP. "Snorkeling" for missing players in cancer. The Journal of Clinical Investigation. 122: 2765-8. PMID 22751102 DOI: 10.1172/Jci63549  0.351
2012 Besin G, Yousefi M, Saba I, Klinck R, Pandolfi PP, Duplay P. Dok-1 overexpression promotes development of γδ natural killer T cells European Journal of Immunology. 42: 2491-2504. PMID 22736313 DOI: 10.1002/Eji.201242421  0.31
2012 Wolyniec K, Shortt J, de Stanchina E, Levav-Cohen Y, Alsheich-Bartok O, Louria-Hayon I, Corneille V, Kumar B, Woods SJ, Opat S, Johnstone RW, Scott CL, Segal D, Pandolfi PP, Fox S, et al. E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis. Blood. 120: 822-32. PMID 22689861 DOI: 10.1182/Blood-2011-10-387647  0.399
2012 Clohessy JG, Reschke M, Pandolfi PP. Found in translation of mTOR signaling. Cell Research. 22: 1315-8. PMID 22641373 DOI: 10.1038/Cr.2012.85  0.312
2012 Berger AH, Knudson AG, Pandolfi PP. Dosage and tumour suppression. The Journal of Pathology. 227: e1; author reply e2. PMID 22488586 DOI: 10.1002/Path.4035  0.624
2012 Song MS, Salmena L, Pandolfi PP. The functions and regulation of the PTEN tumour suppressor. Nature Reviews. Molecular Cell Biology. 13: 283-96. PMID 22473468 DOI: 10.1038/Nrm3330  0.393
2012 Ventelä S, Côme C, Mäkelä JA, Hobbs RM, Mannermaa L, Kallajoki M, Chan EK, Pandolfi PP, Toppari J, Westermarck J. CIP2A promotes proliferation of spermatogonial progenitor cells and spermatogenesis in mice. Plos One. 7: e33209. PMID 22461891 DOI: 10.1371/Journal.Pone.0033209  0.385
2012 Chen Z, Cheng K, Walton Z, Wang Y, Ebi H, Shimamura T, Liu Y, Tupper T, Ouyang J, Li J, Gao P, Woo MS, Xu C, Yanagita M, Altabef A, ... ... Pandolfi PP, et al. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response. Nature. 483: 613-7. PMID 22425996 DOI: 10.1038/Nature10937  0.327
2012 Garcia-Cao I, Song MS, Hobbs RM, Laurent G, Giorgi C, de Boer VC, Anastasiou D, Ito K, Sasaki AT, Rameh L, Carracedo A, Vander Heiden MG, Cantley LC, Pinton P, Haigis MC, ... Pandolfi PP, et al. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell. 149: 49-62. PMID 22401813 DOI: 10.1016/J.Cell.2012.02.030  0.384
2012 Hobbs RM, Fagoonee S, Papa A, Webster K, Altruda F, Nishinakamura R, Chai L, Pandolfi PP. Functional antagonism between Sall4 and Plzf defines germline progenitors. Cell Stem Cell. 10: 284-98. PMID 22385656 DOI: 10.1016/J.Stem.2012.02.004  0.342
2012 Scaglioni PP, Rabellino A, Yung TM, Bernardi R, Choi S, Konstantinidou G, Nardella C, Cheng K, Pandolfi PP. Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence. Embo Molecular Medicine. 4: 594-602. PMID 22359342 DOI: 10.1002/Emmm.201200233  0.39
2012 Tsuji-Takechi K, Negishi-Koga T, Sumiya E, Kukita A, Kato S, Maeda T, Pandolfi PP, Moriyama K, Takayanagi H. Stage-specific functions of leukemia/lymphoma-related factor (LRF) in the transcriptional control of osteoclast development Proceedings of the National Academy of Sciences of the United States of America. 109: 2561-2566. PMID 22308398 DOI: 10.1073/Pnas.1116042109  0.343
2012 Stroopinsky D, Rosenblatt J, Mills H, Nardella C, Ito K, Yin L, Rajabi H, Vasir B, Kufe T, Luptakova K, Arnason JE, Levine JD, Joyce R, Tzachanis D, Boussiotis VA, ... ... Pandolfi PP, et al. Targeting Leukemia Initiating Cells by MUC1-C Subunit Inhibition Blood. 120: 3583-3583. DOI: 10.1182/Blood.V120.21.3583.3583  0.352
2012 Ito K, Carracedo A, Arai F, Ala U, Avigan D, Schafer Z, Evans RM, Suda T, Lee C, Pandolfi PP. A PML–PPAR-δ Pathway for Fatty Acid Oxidation Regulates Hematopoietic Stem Cell Maintenance Through the Control of Asymmetric Division. Blood. 120: 2327-2327. DOI: 10.1182/Blood.V120.21.2327.2327  0.372
2012 Pandolfi PP. Abstract IA16: The ceRNA hypothesis and the non-coding revolution in cancer research and therapy Cancer Research. 72: IA16-IA16. DOI: 10.1158/1538-7445.Nonrna12-Ia16  0.339
2012 Patnaik A, Courtney K, Robichaud K, Bellinger G, Nardella C, Signoretti S, Wooster R, Pandolfi PP, Cantley L. Abstract LB-365: Effective use of PI3K/MTOR and MEK inhibitors prior to hormone ablative therapy in PTEN-loss driven murine prostate cancer Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-365  0.374
2011 Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM. Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell. 20: 635-48. PMID 22094257 DOI: 10.1016/J.Ccr.2011.10.014  0.357
2011 Karreth FA, Tay Y, Perna D, Ala U, Tan SM, Rust AG, DeNicola G, Webster KA, Weiss D, Perez-Mancera PA, Krauthammer M, Halaban R, Provero P, Adams DJ, Tuveson DA, Pandolfi PP, et al. In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell. 147: 382-95. PMID 22000016 DOI: 10.1016/J.Cell.2011.09.032  0.44
2011 Tay Y, Kats L, Salmena L, Weiss D, Tan SM, Ala U, Karreth F, Poliseno L, Provero P, Di Cunto F, Lieberman J, Rigoutsos I, Pandolfi PP. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell. 147: 344-57. PMID 22000013 DOI: 10.1016/J.Cell.2011.09.029  0.364
2011 Boichuk S, Hu L, Makielski K, Pandolfi PP, Gjoerup OV. Functional connection between Rad51 and PML in homology-directed repair. Plos One. 6: e25814. PMID 21998700 DOI: 10.1371/Journal.Pone.0025814  0.333
2011 Berger AH, Knudson AG, Pandolfi PP. A continuum model for tumour suppression. Nature. 476: 163-9. PMID 21833082 DOI: 10.1038/Nature10275  0.666
2011 Scaglioni PP, Cai LF, Majid SM, Yung TM, Socci ND, Kogan SC, Kopelovich L, Pandolfi PP. Treatment with 5-azacytidine accelerates acute promyelocytic leukemia leukemogenesis in a transgenic mouse model. Genes & Cancer. 2: 160-5. PMID 21779489 DOI: 10.1177/1947601911410300  0.332
2011 Lunardi A, Gaboli M, Giorgio M, Rivi R, Bygrave A, Antoniou M, Drabek D, Dzierzak E, Fagioli M, Salmena L, Botto M, Cordon-Cardo C, Luzzatto L, Pelicci PG, Grosveld F, ... Pandolfi PP, et al. A Role for PML in Innate Immunity. Genes & Cancer. 2: 10-9. PMID 21779477 DOI: 10.1177/1947601911402682  0.327
2011 Nardella C, Clohessy JG, Alimonti A, Pandolfi PP. Pro-senescence therapy for cancer treatment. Nature Reviews. Cancer. 11: 503-11. PMID 21701512 DOI: 10.1038/Nrc3057  0.317
2011 Jham BC, Ma T, Hu J, Chaisuparat R, Friedman ER, Pandolfi PP, Schneider A, Sodhi A, Montaner S. Amplification of the angiogenic signal through the activation of the TSC/mTOR/HIF axis by the KSHV vGPCR in Kaposi's sarcoma. Plos One. 6: e19103. PMID 21559457 DOI: 10.1371/Journal.Pone.0019103  0.368
2011 Carracedo A, Ito K, Pandolfi PP. The nuclear bodies inside out: PML conquers the cytoplasm. Current Opinion in Cell Biology. 23: 360-6. PMID 21501958 DOI: 10.1016/J.Ceb.2011.03.011  0.373
2011 Pinton P, Giorgi C, Pandolfi PP. The role of PML in the control of apoptotic cell fate: a new key player at ER-mitochondria sites. Cell Death and Differentiation. 18: 1450-6. PMID 21475307 DOI: 10.1038/Cdd.2011.31  0.322
2011 Nardella C, Lunardi A, Fedele G, Clohessy JG, Alimonti A, Kozma SC, Thomas G, Loda M, Pandolfi PP. Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis. Cancer Research. 71: 3669-75. PMID 21444676 DOI: 10.1158/0008-5472.Can-10-3962  0.367
2011 Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB, Pandolfi PP, Haigis MC. SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell. 19: 416-28. PMID 21397863 DOI: 10.1016/J.Ccr.2011.02.014  0.379
2011 Bernardi R, Papa A, Egia A, Coltella N, Teruya-Feldstein J, Signoretti S, Pandolfi PP. Pml represses tumour progression through inhibition of mTOR. Embo Molecular Medicine. 3: 249-57. PMID 21387562 DOI: 10.1002/Emmm.201100130  0.306
2011 Carracedo A, Alimonti A, Pandolfi PP. PTEN level in tumor suppression: how much is too little? Cancer Research. 71: 629-33. PMID 21266353 DOI: 10.1158/0008-5472.Can-10-2488  0.418
2011 Song MS, Carracedo A, Salmena L, Song SJ, Egia A, Malumbres M, Pandolfi PP. Nuclear PTEN regulates the APC-CDH1 tumor-suppressive complex in a phosphatase-independent manner. Cell. 144: 187-99. PMID 21241890 DOI: 10.1016/J.Cell.2010.12.020  0.419
2011 Berger AH, Pandolfi PP. Haplo-insufficiency: a driving force in cancer. The Journal of Pathology. 223: 137-46. PMID 21125671 DOI: 10.1002/Path.2800  0.671
2011 Nardella C, Carracedo A, Salmena L, Pandolfi PP. Faithfull modeling of PTEN loss driven diseases in the mouse. Current Topics in Microbiology and Immunology. 347: 135-68. PMID 20549475 DOI: 10.1007/82_2010_62  0.384
2011 Abayasekara N, Levine M, Bolli N, Sun H, Silver M, Nia N, Sportoletti P, Pandolfi PP, Berliner N, Khanna-Gupta A. Upregulation of eIF4E in Nucleophosmin 1 (NPM1) Haploinsufficient Cells Alters CCAAT Enhancer Binding Protein Alpha (C/EBPα) Activity: Implications for MDS and AML Blood. 118: 2432-2432. DOI: 10.1182/Blood.V118.21.2432.2432  0.381
2010 Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M, Bononi A, Bonora M, Duszynski J, Bernardi R, Rizzuto R, Tacchetti C, Pinton P, Pandolfi PP. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science (New York, N.Y.). 330: 1247-51. PMID 21030605 DOI: 10.1126/Science.1189157  0.309
2010 De Keersmaecker K, Real PJ, Gatta GD, Palomero T, Sulis ML, Tosello V, Van Vlierberghe P, Barnes K, Castillo M, Sole X, Hadler M, Lenz J, Aplan PD, Kelliher M, Kee BL, ... Pandolfi PP, et al. The TLX1 oncogene drives aneuploidy in T cell transformation. Nature Medicine. 16: 1321-7. PMID 20972433 DOI: 10.1038/Nm.2246  0.393
2010 Hobbs RM, Seandel M, Falciatori I, Rafii S, Pandolfi PP. Plzf regulates germline progenitor self-renewal by opposing mTORC1. Cell. 142: 468-79. PMID 20691905 DOI: 10.1016/J.Cell.2010.06.041  0.344
2010 Furic L, Rong L, Larsson O, Koumakpayi IH, Yoshida K, Brueschke A, Petroulakis E, Robichaud N, Pollak M, Gaboury LA, Pandolfi PP, Saad F, Sonenberg N. eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 14134-9. PMID 20679199 DOI: 10.1073/Pnas.1005320107  0.394
2010 Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature. 465: 1033-8. PMID 20577206 DOI: 10.1038/Nature09144  0.333
2010 Alimonti A, Carracedo A, Clohessy JG, Trotman LC, Nardella C, Egia A, Salmena L, Sampieri K, Haveman WJ, Brogi E, Richardson AL, Zhang J, Pandolfi PP. Subtle variations in Pten dose determine cancer susceptibility. Nature Genetics. 42: 454-8. PMID 20400965 DOI: 10.1038/Ng.556  0.341
2010 Chan CH, Lee SW, Li CF, Wang J, Yang WL, Wu CY, Wu J, Nakayama KI, Kang HY, Huang HY, Hung MC, Pandolfi PP, Lin HK. Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. Nature Cell Biology. 12: 457-67. PMID 20383141 DOI: 10.1038/Ncb2047  0.397
2010 Fagoonee S, Hobbs RM, De Chiara L, Cantarella D, Piro RM, Tolosano E, Medico E, Provero P, Pandolfi PP, Silengo L, Altruda F. Generation of functional hepatocytes from mouse germ line cell-derived pluripotent stem cells in vitro. Stem Cells and Development. 19: 1183-94. PMID 20331356 DOI: 10.1089/Scd.2009.0496  0.342
2010 Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence. Nature. 464: 374-9. PMID 20237562 DOI: 10.1038/Nature08815  0.718
2010 Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggiò M, Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E, Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, et al. Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis. Developmental Cell. 18: 486-95. PMID 20230755 DOI: 10.1016/J.Devcel.2009.12.020  0.381
2010 Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis Journal of Clinical Investigation. 120: 681-693. PMID 20197621 DOI: 10.1172/Jci40535  0.444
2010 Berger AH, Niki M, Morotti A, Taylor BS, Socci ND, Viale A, Brennan C, Szoke J, Motoi N, Rothman PB, Teruya-Feldstein J, Gerald WL, Ladanyi M, Pandolfi PP. Identification of DOK genes as lung tumor suppressors. Nature Genetics. 42: 216-23. PMID 20139980 DOI: 10.1038/Ng.527  0.674
2010 Nie D, Di Nardo A, Han JM, Baharanyi H, Kramvis I, Huynh T, Dabora S, Codeluppi S, Pandolfi PP, Pasquale EB, Sahin M. Tsc2-Rheb signaling regulates EphA-mediated axon guidance. Nature Neuroscience. 13: 163-72. PMID 20062052 DOI: 10.1038/Nn.2477  0.335
2010 Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X, Mengozzi G, Altruda F, Sorba G, Guan K, Pandolfi PP, Wymann MP, Hirsch E. Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility. Molecular Biology of the Cell. 21: 704-11. PMID 20053680 DOI: 10.1091/Mbc.E09-08-0744  0.356
2010 Alonzo ES, Gottschalk RA, Das J, Egawa T, Hobbs RM, Pandolfi PP, Pereira P, Nichols KE, Koretzky GA, Jordan MS, Sant'Angelo DB. Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3. Journal of Immunology (Baltimore, Md. : 1950). 184: 1268-79. PMID 20038637 DOI: 10.4049/Jimmunol.0903218  0.317
2010 Hobbs RM, Pandolfi PP. Shape-shifting and tumor suppression by PLZF Oncotarget. 1: 3-5. DOI: 10.18632/Oncotarget.102  0.328
2010 Alimonti A, Nardella C, Pavese I, Clohessy JG, Carracedo A, Trotman LC, Woscholski R, Cognetti F, Scher HI, Pandolfi P. PTEN and MDM2 inhibitors: Toward a novel pro-senescence therapy approach for patients with cancer. Journal of Clinical Oncology. 28: e13572-e13572. DOI: 10.1200/Jco.2010.28.15_Suppl.E13572  0.382
2010 Pandolfi PP. A Dual Proto-Oncogenic and Tumor Suppressive Role of LRF/POKEMON In Hemopoietic Malignancies through Control of Cell Fate Decision Blood. 116: SCI-14-SCI-14. DOI: 10.1182/Blood.V116.21.Sci-14.Sci-14  0.447
2010 Ito K, Sportoletti P, Clohessy JG, Silvia G, Pandolfi PP. The Role of Nucleophosmin In Hematopoietic Stem Cells and the Pathogenesis of Myelodysplastic Syndrome Blood. 116: 95-95. DOI: 10.1182/Blood.V116.21.95.95  0.404
2010 Stroopinsky D, Rosenblatt J, Ito K, Yin L, Rajabi H, Vasir B, Kufe T, Glotzbecker B, Luptakova K, Mills H, Joyce R, Tzachanis D, Boussiotis VA, Levine J, Galinsky I, ... ... Pandolfi PP, et al. Targeting Acute Myeloid Leukemia Stem Cells by MUC1-C Subunit Inhibition Blood. 116: 848-848. DOI: 10.1182/Blood.V116.21.848.848  0.336
2010 De Keersmaecker K, Real PJ, Gatta GD, Palomero T, Sulis ML, Tosello V, Van Vlierberghe P, Barnes K, Castillo M, Sole X, Hadler M, Lenz J, Aplan P, Kelliher M, Kee BL, ... Pandolfi PP, et al. BCL11B Mutations In T-Cell Acute Lymphoblastic Leukemia Blood. 116: 471-471. DOI: 10.1182/Blood.V116.21.471.471  0.371
2010 Rau RE, Magoon D, McIntyre E, Li L, Greenblatt S, Huso D, Pandolfi PP, Small D, Brown P. Cytoplasmic Nucleophosmin (NPMc+) Mutations and FMS-Like Tyrosine Kinase 3 (Flt3) Internal Tandem Duplication (ITD) Mutations Cooperate to Cause Leukemia In a Mouse Model Blood. 116: 145-145. DOI: 10.1182/Blood.V116.21.145.145  0.313
2010 Lin H, Chen Z, Wang G, Nardella C, Lee S, Chan C, Yang W, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Erratum: Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence Nature. 466: 398-398. DOI: 10.1038/Nature09280  0.676
2009 Maeda T, Ito K, Merghoub T, Poliseno L, Hobbs RM, Wang G, Dong L, Maeda M, Dore LC, Zelent A, Luzzatto L, Teruya-Feldstein J, Weiss MJ, Pandolfi PP. LRF is an essential downstream target of GATA1 in erythroid development and regulates BIM-dependent apoptosis. Developmental Cell. 17: 527-40. PMID 19853566 DOI: 10.1016/J.Devcel.2009.09.005  0.706
2009 Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP. Differential p53-independent outcomes of p19(Arf) loss in oncogenesis. Science Signaling. 2: ra44. PMID 19690330 DOI: 10.1126/Scisignal.2000053  0.344
2009 Cheng K, Sportoletti P, Ito K, Clohessy JG, Teruya-Feldstein J, Kutok JL, Pandolfi PP. The cytoplasmic NPM mutant induces myeloproliferation in a transgenic mouse model. Blood. 115: 3341-5. PMID 19666870 DOI: 10.1182/Blood-2009-03-208587  0.34
2009 Gewinner C, Wang ZC, Richardson A, Teruya-Feldstein J, Etemadmoghadam D, Bowtell D, Barretina J, Lin WM, Rameh L, Salmena L, Pandolfi PP, Cantley LC. Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Cancer Cell. 16: 115-25. PMID 19647222 DOI: 10.1016/J.Ccr.2009.06.006  0.402
2009 Kreslavsky T, Savage AK, Hobbs R, Gounari F, Bronson R, Pereira P, Pandolfi PP, Bendelac A, von Boehmer H. TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity. Proceedings of the National Academy of Sciences of the United States of America. 106: 12453-8. PMID 19617548 DOI: 10.1073/Pnas.0903895106  0.342
2009 Xu D, Holko M, Sadler AJ, Scott B, Higashiyama S, Berkofsky-Fessler W, McConnell MJ, Pandolfi PP, Licht JD, Williams BR. Promyelocytic leukemia zinc finger protein regulates interferon-mediated innate immunity. Immunity. 30: 802-16. PMID 19523849 DOI: 10.1016/J.Immuni.2009.04.013  0.316
2009 Gutierrez A, Sanda T, Grebliunaite R, Carracedo A, Salmena L, Ahn Y, Dahlberg S, Neuberg D, Moreau LA, Winter SS, Larson R, Zhang J, Protopopov A, Chin L, Pandolfi PP, et al. High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia. Blood. 114: 647-50. PMID 19458356 DOI: 10.1182/Blood-2009-02-206722  0.335
2009 Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Lorente M, Egia A, Vázquez P, Blázquez C, Torres S, García S, Nowak J, Fimia GM, Piacentini M, Cecconi F, Pandolfi PP, et al. Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. The Journal of Clinical Investigation. 119: 1359-72. PMID 19425170 DOI: 10.1172/Jci37948  0.396
2009 Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nature Genetics. 41: 619-24. PMID 19396168 DOI: 10.1038/Ng.370  0.347
2009 Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Khahariza P, Oscarsson J, Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, ... Pandolfi PP, et al. Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death and Differentiation. 16: 1018-29. PMID 19390558 DOI: 10.1038/Cdd.2009.46  0.313
2009 Clohessy JG, Pandolfi PP. beta-tting on p63 as a metastatic suppressor. Cell. 137: 28-30. PMID 19345184 DOI: 10.1016/J.Cell.2009.03.028  0.315
2009 Fumagalli S, Di Cara A, Neb-Gulati A, Natt F, Schwemberger S, Hall J, Babcock GF, Bernardi R, Pandolfi PP, Thomas G. Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nature Cell Biology. 11: 501-8. PMID 19287375 DOI: 10.1038/Ncb1858  0.323
2009 Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH, Yang WL, Erdjument-Bromage H, Nakayama KI, Nimer S, Tempst P, Pandolfi PP. Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nature Cell Biology. 11: 420-32. PMID 19270694 DOI: 10.1038/Ncb1849  0.713
2009 Distefano G, Boca M, Rowe I, Wodarczyk C, Ma L, Piontek KB, Germino GG, Pandolfi PP, Boletta A. Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1. Molecular and Cellular Biology. 29: 2359-71. PMID 19255143 DOI: 10.1128/Mcb.01259-08  0.458
2009 Ito K, Bernardi R, Pandolfi PP. A novel signaling network as a critical rheostat for the biology and maintenance of the normal stem cell and the cancer-initiating cell. Current Opinion in Genetics & Development. 19: 51-9. PMID 19216069 DOI: 10.1016/J.Gde.2009.01.004  0.377
2009 Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP. Differential requirement of mTOR in postmitotic tissues and tumorigenesis. Science Signaling. 2: ra2. PMID 19176516 DOI: 10.1126/Scisignal.2000189  0.407
2009 Li L, Dutra A, Pak E, Labrie JE, Gerstein RM, Pandolfi PP, Recht LD, Ross AH. EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors. Neuro-Oncology. 11: 9-21. PMID 18812521 DOI: 10.1215/15228517-2008-081  0.403
2009 Teitell MA, Pandolfi PP. Molecular genetics of acute lymphoblastic leukemia. Annual Review of Pathology. 4: 175-98. PMID 18783329 DOI: 10.1146/Annurev.Pathol.4.110807.092227  0.359
2009 Cheng S, Hsia CY, Feng B, Liou ML, Fang X, Pandolfi PP, Liou HC. BCR-mediated apoptosis associated with negative selection of immature B cells is selectively dependent on Pten. Cell Research. 19: 196-207. PMID 18781138 DOI: 10.1038/Cr.2008.284  0.332
2009 Liu Y, Liu F, Zhao X, Sashida G, Deblasio A, Chen Z, Lin H, Di Giandomenico S, Elf S, Yang Y, Miyata Y, Huang G, Menendez S, Mellinghoff I, Pandolfi PP, et al. Akt-Mediated Phosphorylation of Bmi1 Regulates Its Chromatin Association and Growth Promoting Properties. Blood. 114: 3605-3605. DOI: 10.1182/Blood.V114.22.3605.3605  0.392
2009 Khanna-Gupta A, Chen J, Silver M, Sun H, Abayasekara N, Halene S, Sportoletti P, Pandolfi PP, Berliner N. Nucleophosmin-1 Interacts with CCAAT Enhancer Binding Protein Alpha (C/EBPα) to Facilitate Granulocyte Maturation: Implications in MDS and AML. Blood. 114: 2768-2768. DOI: 10.1182/Blood.V114.22.2768.2768  0.406
2009 Sportoletti P, Clohessy JG, Riccardi L, Khanna-Gupta A, Chen J, Berliner N, Pandolfi PP. Nucleophosmin Is Required for Macrophage Function and Maturation. Blood. 114: 238-238. DOI: 10.1182/Blood.V114.22.238.238  0.341
2009 Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Björklund A, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, Pandolfi PP, et al. Erratum: Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy Cell Death & Differentiation. 16: 1071-1071. DOI: 10.1038/Cdd.2009.64  0.313
2009 Scaglioni PP, Yung TM, Choi S, Baldini C, Konstantinidou G, Pandolfi PP. CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor Molecular and Cellular Biochemistry. 327: 279-279. DOI: 10.1007/S11010-009-0122-5  0.328
2008 Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G, Pandolfi PP, Givol D, Strano S, Lu X, Blandino G. PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Molecular Cell. 32: 803-14. PMID 19111660 DOI: 10.1016/J.Molcel.2008.11.019  0.384
2008 Carracedo A, Baselga J, Pandolfi PP. Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors. Cell Cycle. 7: 3805-3809. PMID 19098454 DOI: 10.4161/Cc.7.24.7244  0.364
2008 Nasr R, Guillemin MC, Ferhi O, Soilihi H, Peres L, Berthier C, Rousselot P, Robledo-Sarmiento M, Lallemand-Breitenbach V, Gourmel B, Vitoux D, Pandolfi PP, Rochette-Egly C, Zhu J, de Thé H. Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation. Nature Medicine. 14: 1333-42. PMID 19029980 DOI: 10.1038/Nm.1891  0.373
2008 Bernardi R, Papa A, Pandolfi PP. Regulation of apoptosis by PML and the PML-NBs. Oncogene. 27: 6299-312. PMID 18931695 DOI: 10.1038/Onc.2008.305  0.405
2008 Maggi LB, Kuchenruether M, Dadey DY, Schwope RM, Grisendi S, Townsend RR, Pandolfi PP, Weber JD. Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. Molecular and Cellular Biology. 28: 7050-65. PMID 18809582 DOI: 10.1128/Mcb.01548-07  0.346
2008 Shima Y, Shima T, Chiba T, Irimura T, Pandolfi PP, Kitabayashi I. PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation. Molecular and Cellular Biology. 28: 7126-38. PMID 18809579 DOI: 10.1128/Mcb.00897-08  0.354
2008 Carracedo A, Pandolfi PP. The PTEN-PI3K pathway: of feedbacks and cross-talks. Oncogene. 27: 5527-41. PMID 18794886 DOI: 10.1038/Onc.2008.247  0.366
2008 Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer Journal of Clinical Investigation. 118: 3065-3074. PMID 18725988 DOI: 10.1172/Jci34739  0.497
2008 Song MS, Salmena L, Carracedo A, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP. The deubiquitinylation and localization of PTEN are regulated by a HAUSP-PML network. Nature. 455: 813-7. PMID 18716620 DOI: 10.1038/Nature07290  0.402
2008 Nardella C, Chen Z, Salmena L, Carracedo A, Alimonti A, Egia A, Carver B, Gerald W, Cordon-Cardo C, Pandolfi PP. Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events. Genes & Development. 22: 2172-7. PMID 18708577 DOI: 10.1101/Gad.1699608  0.374
2008 Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K, Eidson M, Kim HJ, Im JS, Pandolfi PP, Sant'Angelo DB. The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions. Nature Immunology. 9: 1055-64. PMID 18660811 DOI: 10.1038/Ni.1641  0.352
2008 Chen S, Ndhlovu LC, Takahashi T, Takeda K, Ikarashi Y, Kikuchi T, Murata K, Pandolfi PP, Riccardi C, Ono M, Sugamura K, Ishii N. Co-inhibitory roles for glucocorticoid-induced TNF receptor in CD1d-dependent natural killer T cells. European Journal of Immunology. 38: 2229-40. PMID 18624295 DOI: 10.1002/Eji.200838167  0.333
2008 Hayakawa F, Abe A, Kitabayashi I, Pandolfi PP, Naoe T. Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis. Journal of Biological Chemistry. 283: 24420-24425. PMID 18621739 DOI: 10.1074/Jbc.M802217200  0.375
2008 Scaglioni PP, Yung TM, Choi S, Choi SC, Baldini C, Konstantinidou G, Pandolfi PP. CK2 mediates phosphorylation and ubiquitin-mediated degradation of the PML tumor suppressor. Molecular and Cellular Biochemistry. 316: 149-54. PMID 18566754 DOI: 10.1007/S11010-008-9812-7  0.413
2008 Ito K, Bernardi R, Morotti A, Matsuoka S, Saglio G, Ikeda Y, Rosenblatt J, Avigan DE, Teruya-Feldstein J, Pandolfi PP. PML targeting eradicates quiescent leukaemia-initiating cells. Nature. 453: 1072-8. PMID 18469801 DOI: 10.1038/Nature07016  0.36
2008 Carracedo A, Salmena L, Pandolfi PP. SnapShot: PTEN signaling pathways. Cell. 133: 550.e1. PMID 18455993 DOI: 10.1016/J.Cell.2008.04.023  0.407
2008 Salmena L, Carracedo A, Pandolfi PP. Tenets of PTEN tumor suppression. Cell. 133: 403-14. PMID 18455982 DOI: 10.1016/J.Cell.2008.04.013  0.393
2008 Hambardzumyan D, Becher OJ, Rosenblum MK, Pandolfi PP, Manova-Todorova K, Holland EC. PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes & Development. 22: 436-48. PMID 18281460 DOI: 10.1101/Gad.1627008  0.398
2008 Costoya JA, Hobbs RM, Pandolfi PP. Cyclin-dependent kinase antagonizes promyelocytic leukemia zinc-finger through phosphorylation. Oncogene. 27: 3789-96. PMID 18246121 DOI: 10.1038/Onc.2008.7  0.426
2008 Sportoletti P, Grisendi S, Majid SM, Cheng K, Clohessy JG, Viale A, Teruya-Feldstein J, Pandolfi PP. Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse. Blood. 111: 3859-62. PMID 18212245 DOI: 10.1182/Blood-2007-06-098251  0.408
2008 Janas ML, Hodson D, Stamataki Z, Hill S, Welch K, Gambardella L, Trotman LC, Pandolfi PP, Vigorito E, Turner M. The effect of deleting p110delta on the phenotype and function of PTEN-deficient B cells. Journal of Immunology (Baltimore, Md. : 1950). 180: 739-46. PMID 18178811 DOI: 10.4049/Jimmunol.180.2.739  0.321
2008 Carracedo A, Song M, Salmena L, Egia A, Lo-Coco F, Teruya-Feldstein J, Pandolfi PP. PML Controls PTEN Localization and Function in APL through a Novel Deubiquitination Pathway Blood. 112: 3812-3812. DOI: 10.1182/Blood.V112.11.3812.3812  0.453
2007 Guidez F, Parks S, Wong H, Jovanovic JV, Mays A, Gilkes AF, Mills KI, Guillemin MC, Hobbs RM, Pandolfi PP, de Thé H, Solomon E, Grimwade D. RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 104: 18694-9. PMID 18000064 DOI: 10.1073/Pnas.0704433104  0.349
2007 Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, et al. Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature. 449: 346-50. PMID 17882221 DOI: 10.1038/Nature06129  0.315
2007 Ma L, Teruya-Feldstein J, Bonner P, Bernardi R, Franz DN, Witte D, Cordon-Cardo C, Pandolfi PP. Identification of S664 TSC2 phosphorylation as a marker for extracellular signal-regulated kinase mediated mTOR activation in tuberous sclerosis and human cancer. Cancer Research. 67: 7106-12. PMID 17671177 DOI: 10.1158/0008-5472.Can-06-4798  0.45
2007 Filipponi D, Hobbs RM, Ottolenghi S, Rossi P, Jannini EA, Pandolfi PP, Dolci S. Repression of kit expression by Plzf in germ cells. Molecular and Cellular Biology. 27: 6770-81. PMID 17664282 DOI: 10.1128/Mcb.00479-07  0.361
2007 Hermann BP, Sukhwani M, Lin CC, Sheng Y, Tomko J, Rodriguez M, Shuttleworth JJ, McFarland D, Hobbs RM, Pandolfi PP, Schatten GP, Orwig KE. Characterization, cryopreservation, and ablation of spermatogonial stem cells in adult rhesus macaques. Stem Cells (Dayton, Ohio). 25: 2330-8. PMID 17585169 DOI: 10.1634/Stemcells.2007-0143  0.316
2007 Yoshida H, Ichikawa H, Tagata Y, Katsumoto T, Ohnishi K, Akao Y, Naoe T, Pandolfi PP, Kitabayashi I. PML-retinoic acid receptor alpha inhibits PML IV enhancement of PU.1-induced C/EBPepsilon expression in myeloid differentiation. Molecular and Cellular Biology. 27: 5819-34. PMID 17562868 DOI: 10.1128/Mcb.02422-06  0.359
2007 Cheng K, Grisendi S, Clohessy JG, Majid S, Bernardi R, Sportoletti P, Pandolfi PP. The leukemia-associated cytoplasmic nucleophosmin mutant is an oncogene with paradoxical functions: Arf inactivation and induction of cellular senescence. Oncogene. 26: 7391-400. PMID 17546053 DOI: 10.1038/Sj.Onc.1210549  0.33
2007 Salmena L, Pandolfi PP. Changing venues for tumour suppression: balancing destruction and localization by monoubiquitylation. Nature Reviews. Cancer. 7: 409-13. PMID 17508027 DOI: 10.1038/Nrc2145  0.344
2007 Hernando E, Charytonowicz E, Dudas ME, Menendez S, Matushansky I, Mills J, Socci ND, Behrendt N, Ma L, Maki RG, Pandolfi PP, Cordon-Cardo C. The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas. Nature Medicine. 13: 748-53. PMID 17496901 DOI: 10.1038/Nm1560  0.45
2007 Maeda T, Merghoub T, Hobbs RM, Dong L, Maeda M, Zakrzewski J, van den Brink MR, Zelent A, Shigematsu H, Akashi K, Teruya-Feldstein J, Cattoretti G, Pandolfi PP. Regulation of B versus T lymphoid lineage fate decision by the proto-oncogene LRF. Science (New York, N.Y.). 316: 860-6. PMID 17495164 DOI: 10.1126/Science.1140881  0.316
2007 Shen WH, Balajee AS, Wang J, Wu H, Eng C, Pandolfi PP, Yin Y. Essential role for nuclear PTEN in maintaining chromosomal integrity. Cell. 128: 157-70. PMID 17218262 DOI: 10.1016/J.Cell.2006.11.042  0.359
2007 Trotman LC, Wang X, Alimonti A, Chen Z, Teruya-Feldstein J, Yang H, Pavletich NP, Carver BS, Cordon-Cardo C, Erdjument-Bromage H, Tempst P, Chi SG, Kim HJ, Misteli T, Jiang X, ... Pandolfi PP, et al. Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression Cell. 128: 141-156. PMID 17218261 DOI: 10.1016/J.Cell.2006.11.040  0.435
2007 Wang X, Trotman LC, Koppie T, Alimonti A, Chen Z, Gao Z, Wang J, Erdjument-Bromage H, Tempst P, Cordon-Cardo C, Pandolfi PP, Jiang X. NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN. Cell. 128: 129-39. PMID 17218260 DOI: 10.1016/J.Cell.2006.11.039  0.447
2007 Hayakawa F, Kitabayashi I, Pandolfi PP, Naoe T. Acetylation of PML Plays a Key Role in Histone Deacetylase Inhibitor-Mediated Apoptosis through Enhanced PML Sumoylation. Blood. 110: 4164-4164. DOI: 10.1182/Blood.V110.11.4164.4164  0.379
2007 Carver BS, Lin H, Chen Z, Trotman L, Scardino PT, Pandolfi PP. 663: XPD (ERCC-2) and Prostate Cancer: Susceptibility Depends on the Degree of DNA Damage and Transcriptional Interference Journal of Urology. 177: 222-223. DOI: 10.1016/S0022-5347(18)30903-0  0.304
2006 Choi YH, Bernardi R, Pandolfi PP, Benveniste EN. The promyelocytic leukemia protein functions as a negative regulator of IFN-gamma signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 18715-20. PMID 17121994 DOI: 10.1073/Pnas.0604800103  0.324
2006 Schefe JH, Menk M, Reinemund J, Effertz K, Hobbs RM, Pandolfi PP, Ruiz P, Unger T, Funke-Kaiser H. A novel signal transduction cascade involving direct physical interaction of the renin/prorenin receptor with the transcription factor promyelocytic zinc finger protein. Circulation Research. 99: 1355-66. PMID 17082479 DOI: 10.1161/01.Res.0000251700.00994.0D  0.385
2006 Shen TH, Lin HK, Scaglioni PP, Yung TM, Pandolfi PP. The mechanisms of PML-nuclear body formation. Molecular Cell. 24: 331-9. PMID 17081985 DOI: 10.1016/J.Molcel.2006.09.013  0.325
2006 Carver BS, Pandolfi PP. Mouse modeling in oncologic preclinical and translational research. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5305-11. PMID 17000663 DOI: 10.1158/1078-0432.Ccr-06-0482  0.324
2006 Bernardi R, Guernah I, Jin D, Grisendi S, Alimonti A, Teruya-Feldstein J, Cordon-Cardo C, Simon MC, Rafii S, Pandolfi PP. PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR. Nature. 442: 779-85. PMID 16915281 DOI: 10.1038/Nature05029  0.379
2006 Joe Y, Jeong JH, Yang S, Kang H, Motoyama N, Pandolfi PP, Chung JH, Kim MK. ATR, PML, and CHK2 play a role in arsenic trioxide-induced apoptosis. The Journal of Biological Chemistry. 281: 28764-71. PMID 16891316 DOI: 10.1074/Jbc.M604392200  0.4
2006 Scaglioni PP, Yung TM, Cai LF, Erdjument-Bromage H, Kaufman AJ, Singh B, Teruya-Feldstein J, Tempst P, Pandolfi PP. A CK2-dependent mechanism for degradation of the PML tumor suppressor. Cell. 126: 269-83. PMID 16873060 DOI: 10.1016/J.Cell.2006.05.041  0.412
2006 Montanaro L, Brigotti M, Clohessy J, Barbieri S, Ceccarelli C, Santini D, Taffurelli M, Calienni M, Teruya-Feldstein J, Trerè D, Pandolfi PP, Derenzini M. Dyskerin expression influences the level of ribosomal RNA pseudo-uridylation and telomerase RNA component in human breast cancer. The Journal of Pathology. 210: 10-8. PMID 16841302 DOI: 10.1002/Path.2023  0.315
2006 Yang S, Jeong JH, Brown AL, Lee CH, Pandolfi PP, Chung JH, Kim MK. Promyelocytic leukemia activates Chk2 by mediating Chk2 autophosphorylation. The Journal of Biological Chemistry. 281: 26645-54. PMID 16835227 DOI: 10.1074/Jbc.M604391200  0.408
2006 Grisendi S, Mecucci C, Falini B, Pandolfi PP. Nucleophosmin and cancer. Nature Reviews. Cancer. 6: 493-505. PMID 16794633 DOI: 10.1038/Nrc1885  0.369
2006 Chen ML, Xu PZ, Peng XD, Chen WS, Guzman G, Yang X, Di Cristofano A, Pandolfi PP, Hay N. The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice. Genes & Development. 20: 1569-74. PMID 16778075 DOI: 10.1101/Gad.1395006  0.401
2006 Bai F, Pei XH, Pandolfi PP, Xiong Y. p18 Ink4c and Pten constrain a positive regulatory loop between cell growth and cell cycle control. Molecular and Cellular Biology. 26: 4564-76. PMID 16738322 DOI: 10.1128/Mcb.00266-06  0.425
2006 Andrés V, Gascón-Irún M, Pandolfi PP, González-Navarro H. Atheroma development in apolipoprotein E-null mice is not affected by partial inactivation of PTEN. Frontiers in Bioscience : a Journal and Virtual Library. 11: 2739-45. PMID 16720346 DOI: 10.2741/2003  0.323
2006 Trotman LC, Alimonti A, Scaglioni PP, Koutcher JA, Cordon-Cardo C, Pandolfi PP. Identification of a tumour suppressor network opposing nuclear Akt function. Nature. 441: 523-7. PMID 16680151 DOI: 10.1038/Nature04809  0.434
2006 Matsushita H, Scaglioni PP, Bhaumik M, Rego EM, Cai LF, Majid SM, Miyachi H, Kakizuka A, Miller WH, Pandolfi PP. In vivo analysis of the role of aberrant histone deacetylase recruitment and RAR alpha blockade in the pathogenesis of acute promyelocytic leukemia. The Journal of Experimental Medicine. 203: 821-8. PMID 16549595 DOI: 10.1084/Jem.20050616  0.355
2006 Zhao M, Janas JA, Niki M, Pandolfi PP, Van Aelst L. Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Molecular and Cellular Biology. 26: 2479-89. PMID 16537894 DOI: 10.1128/Mcb.26.7.2479-2489.2006  0.373
2006 Shaffer DR, Pandolfi PP. Breaking the rules of cancer. Nature Medicine. 12: 14-5. PMID 16397543 DOI: 10.1038/Nm0106-14  0.343
2006 Rego EM, Ruggero D, Tribioli C, Cattoretti G, Kogan S, Redner RL, Pandolfi PP. Leukemia with distinct phenotypes in transgenic mice expressing PML/RAR alpha, PLZF/RAR alpha or NPM/RAR alpha. Oncogene. 25: 1974-9. PMID 16331271 DOI: 10.1038/Sj.Onc.1209216  0.578
2006 Bernassola F, Oberst A, Melino G, Pandolfi PP. The promyelocytic leukaemia protein tumour suppressor functions as a transcriptional regulator of p63. Oncogene. 24: 6982-6. PMID 16007146 DOI: 10.1038/Sj.Onc.1208843  0.358
2006 Maeda T, Merghoub T, Dong L, Maeda M, Hobbs R, Zakrzewski J, Brink Mvd, Shigematsu H, Akashi K, Zelent A, Teruya-Feldstein J, Cattoretti G, Pandolfi PP. LRF/Pokemon Plays a Pivotal Role in B Versus T Lymphoid Lineage Fate Decision at the Early Lymphoid Progenitor Stage by Opposing Notch1 Signaling. Blood. 108: 778-778. DOI: 10.1182/Blood.V108.11.778.778  0.355
2006 Santana-Lemos BA, Guibal F, Pintao M, Scheucher PS, Abreu-Lima RS, Teixeira HL, Pandolfi PP, Tenen DG, Rego EM. In Vivo Analysis of the Role of C/EBPα in Acute Promyelocytic Leukemia Genesis. Blood. 108: 1937-1937. DOI: 10.1182/Blood.V108.11.1937.1937  0.302
2006 Scaglioni PP, Yung TM, Cai LF, Erdjument-Bromage H, Kaufman AJ, Singh B, Teruya-Feldstein J, Tempst P, Pandolfi PP. A CK2-Dependent Mechanism for PML Degradation upon Cellular and Oncogenic Stress. Blood. 108: 1426-1426. DOI: 10.1182/Blood.V108.11.1426.1426  0.434
2006 Cheng K, Grisendi S, Clohessy JG, Majid S, Sportoletti P, Pandolfi PP. Elucidating the Oncogenic Potential of NPMc+ In Vitro and In Vivo. Blood. 108: 12-12. DOI: 10.1182/Blood.V108.11.12.12  0.389
2005 Nacerddine K, Lehembre F, Bhaumik M, Artus J, Cohen-Tannoudji M, Babinet C, Pandolfi PP, Dejean A. The SUMO pathway is essential for nuclear integrity and chromosome segregation in mice. Developmental Cell. 9: 769-79. PMID 16326389 DOI: 10.1016/J.Devcel.2005.10.007  0.357
2005 Maeda T, Hobbs RM, Pandolfi PP. The transcription factor Pokemon: a new key player in cancer pathogenesis. Cancer Research. 65: 8575-8. PMID 16204018 DOI: 10.1158/0008-5472.Can-05-1055  0.409
2005 Wang J, Devgan V, Corrado M, Prabhu NS, El-Deiry WS, Riccardi C, Pandolfi PP, Missero C, Dotto GP. Glucocorticoid-induced tumor necrosis factor receptor is a p21Cip1/WAF1 transcriptional target conferring resistance of keratinocytes to UV light-induced apoptosis. The Journal of Biological Chemistry. 280: 37725-31. PMID 16155000 DOI: 10.1074/Jbc.M507976200  0.379
2005 Chen Z, Trotman LC, Shaffer D, Lin HK, Dotan ZA, Niki M, Koutcher JA, Scher HI, Ludwig T, Gerald W, Cordon-Cardo C, Pandolfi PP. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature. 436: 725-30. PMID 16079851 DOI: 10.1038/Nature03918  0.395
2005 Ma L, Teruya-Feldstein J, Behrendt N, Chen Z, Noda T, Hino O, Cordon-Cardo C, Pandolfi PP. Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression. Genes & Development. 19: 1779-86. PMID 16027168 DOI: 10.1101/Gad.1314405  0.47
2005 Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K, Pandolfi PP. Role of nucleophosmin in embryonic development and tumorigenesis. Nature. 437: 147-53. PMID 16007073 DOI: 10.1038/Nature03915  0.395
2005 Hu X, Pandolfi PP, Li Y, Koutcher JA, Rosenblum M, Holland EC. mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma. Neoplasia (New York, N.Y.). 7: 356-68. PMID 15967113 DOI: 10.1593/Neo.04595  0.41
2005 Xiao A, Yin C, Yang C, Di Cristofano A, Pandolfi PP, Van Dyke T. Somatic induction of Pten loss in a preclinical astrocytoma model reveals major roles in disease progression and avenues for target discovery and validation. Cancer Research. 65: 5172-80. PMID 15958561 DOI: 10.1158/0008-5472.Can-04-3902  0.431
2005 Oberst A, Rossi M, Salomoni P, Pandolfi PP, Oren M, Melino G, Bernassola F. Regulation of the p73 protein stability and degradation. Biochemical and Biophysical Research Communications. 331: 707-12. PMID 15865926 DOI: 10.1016/J.Bbrc.2005.03.158  0.413
2005 Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP. Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell. 121: 179-93. PMID 15851026 DOI: 10.1016/J.Cell.2005.02.031  0.479
2005 Cairo S, De Falco F, Pizzo M, Salomoni P, Pandolfi PP, Meroni G. PML interacts with Myc, and Myc target gene expression is altered in PML-null fibroblasts. Oncogene. 24: 2195-203. PMID 15735755 DOI: 10.1038/Sj.Onc.1208338  0.381
2005 Maeda T, Hobbs RM, Merghoub T, Guernah I, Zelent A, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP. Role of the proto-oncogene Pokemon in cellular transformation and ARF repression. Nature. 433: 278-85. PMID 15662416 DOI: 10.1038/Nature03203  0.392
2005 Grisendi S, Pandolfi PP. NPM mutations in acute myelogenous leukemia. The New England Journal of Medicine. 352: 291-2. PMID 15659732 DOI: 10.1056/Nejme048337  0.343
2005 Oki S, Limnander A, Yao PM, Niki M, Pandolfi PP, Rothman PB. Dok1 and SHIP act as negative regulators of v-Abl-induced pre-B cell transformation, proliferation and Ras/Erk activation. Cell Cycle (Georgetown, Tex.). 4: 310-4. PMID 15655368 DOI: 10.4161/Cc.4.2.1417  0.345
2005 Salomoni P, Bernardi R, Bergmann S, Changou A, Tuttle S, Pandolfi PP. The promyelocytic leukemia protein PML regulates c-Jun function in response to DNA damage. Blood. 105: 3686-90. PMID 15626733 DOI: 10.1182/Blood-2004-09-3782  0.357
2005 Okabe S, Fukuda S, Kim YJ, Niki M, Pelus LM, Ohyashiki K, Pandolfi PP, Broxmeyer HE. Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1. Blood. 105: 474-80. PMID 15345598 DOI: 10.1182/Blood-2004-03-0843  0.327
2005 Teruya-Feldstein J, Maeda T, Filatov A, Pandolfi P. Analyses of Pokemon Protein Expression in Lymphoma Reveals Elevated Expression in Nodular Lymphocyte Predominant Hodgkin Lymphoma Compared to Classical Hodgkin Lymphoma. Blood. 106: 965-965. DOI: 10.1182/Blood.V106.11.965.965  0.341
2005 Grisendi S, Bernardi R, Rossi M, Cheng K, Khandker L, Manova K, Pandolfi PP. Role of NPM in the Control of Genetic Stability and Tumorigenesis. Blood. 106: 1595-1595. DOI: 10.1182/Blood.V106.11.1595.1595  0.355
2004 Niki M, Di Cristofano A, Zhao M, Honda H, Hirai H, Van Aelst L, Cordon-Cardo C, Pandolfi PP. Role of Dok-1 and Dok-2 in leukemia suppression. The Journal of Experimental Medicine. 200: 1689-95. PMID 15611295 DOI: 10.1084/Jem.20041306  0.371
2004 Piazza F, Costoya JA, Merghoub T, Hobbs RM, Pandolfi PP. Disruption of PLZP in mice leads to increased T-lymphocyte proliferation, cytokine production, and altered hematopoietic stem cell homeostasis. Molecular and Cellular Biology. 24: 10456-69. PMID 15542853 DOI: 10.1128/Mcb.24.23.10456-10469.2004  0.395
2004 Montanaro L, Pandolfi PP. Initiation of mRNA translation in oncogenesis: the role of eIF4E. Cell Cycle (Georgetown, Tex.). 3: 1387-9. PMID 15492504 DOI: 10.4161/Cc.3.11.1251  0.412
2004 Nguyen LA, Pandolfi PP, Aikawa Y, Tagata Y, Ohki M, Kitabayashi I. Physical and functional link of the leukemia-associated factors AML1 and PML. Blood. 105: 292-300. PMID 15331439 DOI: 10.1182/Blood-2004-03-1185  0.365
2004 Engelhardt OG, Sirma H, Pandolfi P, Haller O. Mx1 GTPase accumulates in distinct nuclear domains and inhibits influenza A virus in cells that lack promyelocytic leukaemia protein nuclear bodies Journal of General Virology. 85: 2315-2326. PMID 15269373 DOI: 10.1099/Vir.0.79795-0  0.332
2004 Ferri AL, Cavallaro M, Braida D, Di Cristofano A, Canta A, Vezzani A, Ottolenghi S, Pandolfi PP, Sala M, DeBiasi S, Nicolis SK. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development (Cambridge, England). 131: 3805-19. PMID 15240551 DOI: 10.1242/Dev.01204  0.328
2004 Bernardi R, Scaglioni PP, Bergmann S, Horn HF, Vousden KH, Pandolfi PP. PML regulates p53 stability by sequestering Mdm2 to the nucleolus. Nature Cell Biology. 6: 665-72. PMID 15195100 DOI: 10.1038/Ncb1147  0.356
2004 Bernassola F, Salomoni P, Oberst A, Di Como CJ, Pagano M, Melino G, Pandolfi PP. Ubiquitin-dependent degradation of p73 is inhibited by PML. The Journal of Experimental Medicine. 199: 1545-57. PMID 15184504 DOI: 10.1084/Jem.20031943  0.34
2004 Costoya JA, Hobbs RM, Barna M, Cattoretti G, Manova K, Sukhwani M, Orwig KE, Wolgemuth DJ, Pandolfi PP. Essential role of Plzf in maintenance of spermatogonial stem cells. Nature Genetics. 36: 653-9. PMID 15156143 DOI: 10.1038/Ng1367  0.372
2004 Kepley CL, Taghavi S, Mackay G, Zhu D, Morel PA, Zhang K, Ryan JJ, Satin LS, Zhang M, Pandolfi PP, Saxon A. Co-aggregation of FcgammaRII with FcepsilonRI on human mast cells inhibits antigen-induced secretion and involves SHIP-Grb2-Dok complexes. The Journal of Biological Chemistry. 279: 35139-49. PMID 15151996 DOI: 10.1074/Jbc.M404318200  0.353
2004 Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T. c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. The Journal of Cell Biology. 165: 493-503. PMID 15148308 DOI: 10.1083/Jcb.200312171  0.337
2004 Ruggero D, Montanaro L, Ma L, Xu W, Londei P, Cordon-Cardo C, Pandolfi PP. The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis. Nature Medicine. 10: 484-6. PMID 15098029 DOI: 10.1038/Nm1042  0.654
2004 Holland EC, Sonenberg N, Pandolfi PP, Thomas G. Signaling control of mRNA translation in cancer pathogenesis. Oncogene. 23: 3138-44. PMID 15094763 DOI: 10.1038/Sj.Onc.1207590  0.41
2004 Pandolfi PP. Aberrant mRNA translation in cancer pathogenesis: an old concept revisited comes finally of age. Oncogene. 23: 3134-7. PMID 15094762 DOI: 10.1038/Sj.Onc.1207618  0.366
2004 Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, Pandolfi PP, Thompson LM, Marsh JL. SUMO modification of Huntingtin and Huntington's disease pathology. Science (New York, N.Y.). 304: 100-4. PMID 15064418 DOI: 10.1126/Science.1092194  0.306
2004 de Stanchina E, Querido E, Narita M, Davuluri RV, Pandolfi PP, Ferbeyre G, Lowe SW. PML is a direct p53 target that modulates p53 effector functions. Molecular Cell. 13: 523-35. PMID 14992722 DOI: 10.1016/S1097-2765(04)00062-0  0.344
2004 Gurrieri C, Capodieci P, Bernardi R, Scaglioni PP, Nafa K, Rush LJ, Verbel DA, Cordon-Cardo C, Pandolfi PP. Loss of the tumor suppressor PML in human cancers of multiple histologic origins. Journal of the National Cancer Institute. 96: 269-79. PMID 14970276 DOI: 10.1093/Jnci/Djh043  0.387
2004 Piccolo E, Vignati S, Maffucci T, Innominato PF, Riley AM, Potter BV, Pandolfi PP, Broggini M, Iacobelli S, Innocenti P, Falasca M. Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway. Oncogene. 23: 1754-65. PMID 14755253 DOI: 10.1038/Sj.Onc.1207296  0.377
2004 Sukhai MA, Wu X, Xuan Y, Zhang T, Reis PP, Dubé K, Rego EM, Bhaumik M, Bailey DJ, Wells RA, Kamel-Reid S, Pandolfi PP. Myeloid leukemia with promyelocytic features in transgenic mice expressing hCG-NuMA-RARalpha. Oncogene. 23: 665-78. PMID 14737102 DOI: 10.1038/Sj.Onc.1207073  0.328
2004 Gurrieri C, Nafa K, Merghoub T, Bernardi R, Capodieci P, Biondi A, Nimer S, Douer D, Cordon-Cardo C, Gallagher R, Pandolfi PP. Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia. Blood. 103: 2358-62. PMID 14630830 DOI: 10.1182/Blood-2003-07-2200  0.339
2004 Xu ZX, Zhao RX, Ding T, Tran TT, Zhang W, Pandolfi PP, Chang KS. Promyelocytic leukemia protein 4 induces apoptosis by inhibition of survivin expression. The Journal of Biological Chemistry. 279: 1838-44. PMID 14597622 DOI: 10.1074/Jbc.M310987200  0.387
2004 Maeda T, Hobbs R, Merghoub T, Guernah I, Zelent A, Teruya-Feldstein J, Pandolfi PP. POKEMON Is a Proto-Oncogene Which Plays a Key Role in Lymphomagenesis. Blood. 104: 3489-3489. DOI: 10.1182/Blood.V104.11.3489.3489  0.382
2004 Niki M, Di Cristofano A, Zhao M, Hirai H, Van Aelst L, Cordon-Cardo C, Pandolfi PP. Critical Role of Dok-1 and Dok-2 in Leukemia Suppression. Blood. 104: 2951-2951. DOI: 10.1182/Blood.V104.11.2951.2951  0.372
2004 Scaglioni PP, Yung T, Cai LF, Pandolfi PP. Activation of the P38 MAPK Pathway Results in Ubiquitin-Proteasome Degradation of the PML Tumor Suppressor Protein. Blood. 104: 2553-2553. DOI: 10.1182/Blood.V104.11.2553.2553  0.401
2003 Trotman LC, Niki M, Dotan ZA, Koutcher JA, Di Cristofano A, Xiao A, Khoo AS, Roy-Burman P, Greenberg NM, Van Dyke T, Cordon-Cardo C, Pandolfi PP. Pten dose dictates cancer progression in the prostate. Plos Biology. 1: E59. PMID 14691534 DOI: 10.1371/Journal.Pbio.0000059  0.37
2003 Bernardi R, Pandolfi PP. Role of PML and the PML-nuclear body in the control of programmed cell death. Oncogene. 22: 9048-57. PMID 14663483 DOI: 10.1038/Sj.Onc.1207106  0.41
2003 Ruzinova MB, Schoer RA, Gerald W, Egan JE, Pandolfi PP, Rafii S, Manova K, Mittal V, Benezra R. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell. 4: 277-89. PMID 14585355 DOI: 10.1016/S1535-6108(03)00240-X  0.343
2003 Louria-Hayon I, Grossman T, Sionov RV, Alsheich O, Pandolfi PP, Haupt Y. The promyelocytic leukemia protein protects p53 from Mdm2-mediated inhibition and degradation. The Journal of Biological Chemistry. 278: 33134-41. PMID 12810724 DOI: 10.1074/Jbc.M301264200  0.323
2003 Ariumi Y, Ego T, Kaida A, Matsumoto M, Pandolfi PP, Shimotohno K. Distinct nuclear body components, PML and SMRT, regulate the trans-acting function of HTLV-1 Tax oncoprotein. Oncogene. 22: 1611-9. PMID 12642864 DOI: 10.1038/Sj.Onc.1206244  0.356
2003 Ruggero D, Pandolfi PP. Does the ribosome translate cancer? Nature Reviews. Cancer. 3: 179-92. PMID 12612653 DOI: 10.1038/Nrc1015  0.653
2003 Carneiro C, Jiao MS, Hu M, Shaffer D, Park M, Pandolfi PP, Cordon-Cardo C, Koff A. p27 deficiency desensitizes Rb-/- cells to signals that trigger apoptosis during pituitary tumor development. Oncogene. 22: 361-9. PMID 12545157 DOI: 10.1038/Sj.Onc.1206163  0.395
2003 Wu WS, Xu ZX, Hittelman WN, Salomoni P, Pandolfi PP, Chang KS. Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway. The Journal of Biological Chemistry. 278: 12294-304. PMID 12540841 DOI: 10.1074/Jbc.M211849200  0.371
2003 Ruggero D, Grisendi S, Piazza F, Rego E, Mari F, Rao PH, Cordon-Cardo C, Pandolfi PP. Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification. Science (New York, N.Y.). 299: 259-62. PMID 12522253 DOI: 10.1126/Science.1079447  0.599
2003 Bernardi R, Pandolfi PP. The nucleolus: at the stem of immortality. Nature Medicine. 9: 24-5. PMID 12514717 DOI: 10.1038/Nm0103-24  0.328
2003 Rego EM, Pandolfi PP. Reciprocal products of chromosomal translocations in human cancer pathogenesis: key players or innocent bystanders? Trends in Molecular Medicine. 8: 396-405. PMID 12127726 DOI: 10.1016/S1471-4914(02)02384-5  0.326
2002 Best JL, Ganiatsas S, Agarwal S, Changou A, Salomoni P, Shirihai O, Meluh PB, Pandolfi PP, Zon LI. SUMO-1 protease-1 regulates gene transcription through PML. Molecular Cell. 10: 843-55. PMID 12419228 DOI: 10.1016/S1097-2765(02)00699-8  0.348
2002 Barna M, Merghoub T, Costoya JA, Ruggero D, Branford M, Bergia A, Samori B, Pandolfi PP. Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. Developmental Cell. 3: 499-510. PMID 12408802 DOI: 10.1016/S1534-5807(02)00289-7  0.616
2002 Kim S, Domon-Dell C, Wang Q, Chung DH, Di Cristofano A, Pandolfi PP, Freund JN, Evers BM. PTEN and TNF-alpha regulation of the intestinal-specific Cdx-2 homeobox gene through a PI3K, PKB/Akt, and NF-kappaB-dependent pathway. Gastroenterology. 123: 1163-78. PMID 12360479 DOI: 10.1053/Gast.2002.36043  0.401
2002 Urnov FD, Rebar EJ, Reik A, Pandolfi PP. Designed transcription factors as structural, functional and therapeutic probes of chromatin in vivo. Fourth in review series on chromatin dynamics. Embo Reports. 3: 610-5. PMID 12101091 DOI: 10.1093/Embo-Reports/Kvf140  0.355
2002 Linggi B, Müller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW. The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. Nature Medicine. 8: 743-50. PMID 12091906 DOI: 10.1038/Nm726  0.373
2002 Xiao A, Wu H, Pandolfi PP, Louis DN, Van Dyke T. Astrocyte inactivation of the pRb pathway predisposes mice to malignant astrocytoma development that is accelerated by PTEN mutation. Cancer Cell. 1: 157-68. PMID 12086874 DOI: 10.1016/S1535-6108(02)00029-6  0.353
2002 Rasheed ZA, Saleem A, Ravee Y, Pandolfi PP, Rubin EH. The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies. Experimental Cell Research. 277: 152-60. PMID 12083797 DOI: 10.1006/Excr.2002.5550  0.317
2002 Ronchetti S, Nocentini G, Riccardi C, Pandolfi PP. Role of GITR in activation response of T lymphocytes. Blood. 100: 350-2. PMID 12070049 DOI: 10.1182/Blood-2001-12-0276  0.326
2002 Li L, Liu F, Salmonsen RA, Turner TK, Litofsky NS, Di Cristofano A, Pandolfi PP, Jones SN, Recht LD, Ross AH. PTEN in neural precursor cells: regulation of migration, apoptosis, and proliferation. Molecular and Cellular Neurosciences. 20: 21-9. PMID 12056837 DOI: 10.1006/Mcne.2002.1115  0.373
2002 Morgan M, Thorburn J, Pandolfi PP, Thorburn A. Nuclear and cytoplasmic shuttling of TRADD induces apoptosis via different mechanisms. The Journal of Cell Biology. 157: 975-84. PMID 12045187 DOI: 10.1083/Jcb.200204039  0.331
2002 Bernardi R, Grisendi S, Pandolfi PP. Modelling haematopoietic malignancies in the mouse and therapeutical implications. Oncogene. 21: 3445-58. PMID 12032781 DOI: 10.1038/Sj.Onc.1205313  0.32
2002 Gandini D, De Angeli C, Aguiari G, Manzati E, Lanza F, Pandolfi PP, Cuneo A, Castoldi GL, del Senno L. Preferential expression of the transcription coactivator HTIF1alpha gene in acute myeloid leukemia and MDS-related AML. Leukemia. 16: 886-93. PMID 11986951 DOI: 10.1038/Sj.Leu.2402452  0.349
2002 Ott VL, Tamir I, Niki M, Pandolfi PP, Cambier JC. Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling. Journal of Immunology (Baltimore, Md. : 1950). 168: 4430-9. PMID 11970986 DOI: 10.4049/Jimmunol.168.9.4430  0.35
2002 Salomoni P, Pandolfi PP. The role of PML in tumor suppression. Cell. 108: 165-70. PMID 11832207 DOI: 10.1016/S0092-8674(02)00626-8  0.382
2002 Wu X, Pandolfi PP. Mouse models for multistep tumorigenesis. Trends in Cell Biology. 11: S2-9. PMID 11684435 DOI: 10.1016/S0962-8924(01)02127-4  0.379
2002 He LZ, Bhaumik M, Tribioli C, Rego EM, Ivins S, Zelent A, Pandolfi PP. Two critical hits for promyelocytic leukemia. Molecular Cell. 6: 1131-41. PMID 11106752 DOI: 10.1016/S1097-2765(00)00111-8  0.352
2002 Lacorazza H, Miyazaki Y, Di Cristofano A, Deblasio A, Hedvat C, Zhang J, Cordon-Cardo C, Mao S, Pandolfi PP, Nimer SD. The ETS Protein MEF Plays a Critical Role in Perforin Gene Expression and the Development of Natural Killer and NK-T Cells Immunity. 17: 437-449. DOI: 10.1016/S1074-7613(02)00422-3  0.385
2001 Ward JO, McConnell MJ, Carlile GW, Pandolfi PP, Licht JD, Freedman LP. The acute promyelocytic leukemia-associated protein, promyelocytic leukemia zinc finger, regulates 1,25-dihydroxyvitamin D(3)-induced monocytic differentiation of U937 cells through a physical interaction with vitamin D(3) receptor. Blood. 98: 3290-300. PMID 11719366 DOI: 10.1182/Blood.V98.12.3290  0.322
2001 He LZ, Tolentino T, Grayson P, Zhong S, Warrell RP, Rifkind RA, Marks PA, Richon VM, Pandolfi PP. Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia. The Journal of Clinical Investigation. 108: 1321-30. PMID 11696577 DOI: 10.1172/Jci11537  0.324
2001 Pandolfi PP. In vivo analysis of the molecular genetics of acute promyelocytic leukemia. Oncogene. 20: 5726-35. PMID 11607822 DOI: 10.1038/Sj.Onc.1204600  0.311
2001 Pandolfi PP. Histone deacetylases and transcriptional therapy with their inhibitors. Cancer Chemotherapy and Pharmacology. S17-9. PMID 11587360 DOI: 10.1007/S002800100322  0.373
2001 Khan MM, Nomura T, Kim H, Kaul SC, Wadhwa R, Zhong S, Pandolfi PP, Ishii S. PML-RARalpha alleviates the transcriptional repression mediated by tumor suppressor Rb. The Journal of Biological Chemistry. 276: 43491-4. PMID 11583987 DOI: 10.1074/Jbc.C100532200  0.398
2001 Costoya JA, Pandolfi PP. The role of promyelocytic leukemia zinc finger and promyelocytic leukemia in leukemogenesis and development. Current Opinion in Hematology. 8: 212-7. PMID 11561158 DOI: 10.1097/00062752-200107000-00006  0.31
2001 Keller P, Payne JL, Tremml G, Greer PA, Gaboli M, Pandolfi PP, Bessler M. FES-Cre targets phosphatidylinositol glycan class A (PIGA) inactivation to hematopoietic stem cells in the bone marrow. The Journal of Experimental Medicine. 194: 581-9. PMID 11535627 DOI: 10.1084/Jem.194.5.581  0.354
2001 Di Cristofano A, Niki M, Zhao M, Karnell FG, Clarkson B, Pear WS, Van Aelst L, Pandolfi PP. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). The Journal of Experimental Medicine. 194: 275-84. PMID 11489947 DOI: 10.1084/Jem.194.3.275  0.357
2001 Zhao M, Schmitz AA, Qin Y, Di Cristofano A, Pandolfi PP, Van Aelst L. Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. The Journal of Experimental Medicine. 194: 265-74. PMID 11489946 DOI: 10.1084/Jem.194.3.265  0.361
2001 Gaboli M, Kotsi PA, Gurrieri C, Cattoretti G, Ronchetti S, Cordon-Cardo C, Broxmeyer HE, Hromas R, Pandolfi PP. Mzf1 controls cell proliferation and tumorigenesis. Genes & Development. 15: 1625-30. PMID 11445537 DOI: 10.1101/Gad.902301  0.409
2001 Regad T, Saib A, Lallemand-Breitenbach V, Pandolfi PP, de Thé H, Chelbi-Alix MK. PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivator. The Embo Journal. 20: 3495-505. PMID 11432836 DOI: 10.1093/Emboj/20.13.3495  0.307
2001 Khan MM, Nomura T, Kim H, Kaul SC, Wadhwa R, Shinagawa T, Ichikawa-Iwata E, Zhong S, Pandolfi PP, Ishii S. Role of PML and PML-RARalpha in Mad-mediated transcriptional repression. Molecular Cell. 7: 1233-43. PMID 11430826 DOI: 10.1016/S1097-2765(01)00257-X  0.375
2001 Lallemand-Breitenbach V, Zhu J, Puvion F, Koken M, Honoré N, Doubeikovsky A, Duprez E, Pandolfi PP, Puvion E, Freemont P, De Thé H. Role of promyelocytic leukemia (PML) sumolation in nuclear body formation, 11S proteasome recruitment, and As2O3-induced PML or PML/retinoic acid receptor α degradation Journal of Experimental Medicine. 193: 1361-1371. PMID 11413191 DOI: 10.1084/Jem.193.12.1361  0.312
2001 Hu P, Beresten SF, van Brabant AJ, Ye TZ, Pandolfi PP, Johnson FB, Guarente L, Ellis NA. Evidence for BLM and Topoisomerase IIIalpha interaction in genomic stability. Human Molecular Genetics. 10: 1287-98. PMID 11406610 DOI: 10.1093/Hmg/10.12.1287  0.314
2001 Liao C, Wang XY, Wei HQ, Li SQ, Merghoub T, Pandolfi PP, Wolgemuth DJ. Altered myelopoiesis and the development of acute myeloid leukemia in transgenic mice overexpressing cyclin A1. Proceedings of the National Academy of Sciences of the United States of America. 98: 6853-8. PMID 11381140 DOI: 10.1073/Pnas.121540098  0.312
2001 Merghoub T, Gurrieri C, Piazza F, Pandolfi PP. Modeling acute promyelocytic leukemia in the mouse: new insights in the pathogenesis of human leukemias. Blood Cells, Molecules & Diseases. 27: 231-48. PMID 11358384 DOI: 10.1006/Bcmd.2001.0385  0.304
2001 Pandolfi PP. Oncogenes and tumor suppressors in the molecular pathogenesis of acute promyelocytic leukemia. Human Molecular Genetics. 10: 769-75. PMID 11257111 DOI: 10.1093/Hmg/10.7.769  0.351
2001 Lehembre F, Müller S, Pandolfi PP, Dejean A. Regulation of Pax3 transcriptional activity by SUMO-1-modified PML. Oncogene. 20: 1-9. PMID 11244500 DOI: 10.1038/Sj.Onc.1204063  0.38
2001 Rego EM, Wang ZG, Peruzzi D, He LZ, Cordon-Cardo C, Pandolfi PP. Role of promyelocytic leukemia (PML) protein in tumor suppression. The Journal of Experimental Medicine. 193: 521-29. PMID 11181703 DOI: 10.1084/Jem.193.4.521  0.434
2001 Rego EM, Pandolfi PP. Analysis of the molecular genetics of acute promyelocytic leukemia in mouse models. Seminars in Hematology. 38: 54-70. PMID 11172540 DOI: 10.1016/S0037-1963(01)90006-X  0.314
2001 Toney LM, Cattoretti G, Graf JA, Merghoub T, Pandolfi PP, Dalla-Favera R, Ye BH, Dent AL. BCL-6 regulates chemokine gene transcription in macrophages. Nature Immunology. 1: 214-20. PMID 10973278 DOI: 10.1038/79749  0.351
2000 Fogal V, Gostissa M, Sandy P, Zacchi P, Sternsdorf T, Jensen K, Pandolfi PP, Will H, Schneider C, Del Sal G. Regulation of p53 activity in nuclear bodies by a specific PML isoform. The Embo Journal. 19: 6185-95. PMID 11080164 DOI: 10.1093/Emboj/19.22.6185  0.351
2000 Guo A, Salomoni P, Luo J, Shih A, Zhong S, Gu W, Pandolfi PP. The function of PML in p53-dependent apoptosis. Nature Cell Biology. 2: 730-6. PMID 11025664 DOI: 10.1038/35036365  0.352
2000 Ruggero D, Wang ZG, Pandolfi PP. The puzzling multiple lives of PML and its role in the genesis of cancer. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 22: 827-35. PMID 10944585 DOI: 10.1002/1521-1878(200009)22:9<827::Aid-Bies8>3.0.Co;2-1  0.658
2000 Pearson M, Carbone R, Sebastiani C, Cioce M, Fagioli M, Saito S, Higashimoto Y, Appella E, Minucci S, Pandolfi PP, Pelicci PG. PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature. 406: 207-10. PMID 10910364 DOI: 10.1038/35018127  0.325
2000 Salomoni P, Pandolfi PP. Transcriptional regulation of cellular transformation. Nature Medicine. 6: 742-4. PMID 10888916 DOI: 10.1038/77459  0.326
2000 Arpaia E, Benveniste P, Di Cristofano A, Gu Y, Dalal I, Kelly S, Hershfield M, Pandolfi PP, Roifman CM, Cohen A. Mitochondrial basis for immune deficiency. Evidence from purine nucleoside phosphorylase-deficient mice. The Journal of Experimental Medicine. 191: 2197-208. PMID 10859343 DOI: 10.1084/Jem.191.12.2197  0.303
2000 Barna M, Hawe N, Niswander L, Pandolfi PP. Plzf regulates limb and axial skeletal patterning. Nature Genetics. 25: 166-72. PMID 10835630 DOI: 10.1038/76014  0.331
2000 Zhong S, Salomoni P, Pandolfi PP. The transcriptional role of PML and the nuclear body. Nature Cell Biology. 2: E85-90. PMID 10806494 DOI: 10.1038/35010583  0.318
2000 Di Cristofano A, Pandolfi PP. The multiple roles of PTEN in tumor suppression. Cell. 100: 387-90. PMID 10693755 DOI: 10.1016/S0092-8674(00)80674-1  0.394
2000 Zhong S, Salomoni P, Ronchetti S, Guo A, Ruggero D, Pandolfi PP. Promyelocytic leukemia protein (PML) and Daxx participate in a novel nuclear pathway for apoptosis. The Journal of Experimental Medicine. 191: 631-40. PMID 10684855 DOI: 10.1084/Jem.191.4.631  0.666
2000 Tsutsui T, Hesabi B, Moons DS, Pandolfi PP, Hansel KS, Koff A, Kiyokawa H. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Molecular and Cellular Biology. 19: 7011-9. PMID 10490638 DOI: 10.1128/Mcb.19.10.7011  0.369
2000 Zhong S, Müller S, Ronchetti S, Freemont PS, Dejean A, Pandolfi PP. Role of SUMO-1–modified PML in nuclear body formation Blood. 95: 2748-2752. DOI: 10.1182/Blood.V95.9.2748.009K31A_2748_2752  0.382
2000 Pandolfi PP. Molecular Genetics of Acute Promyelocytic Leukemia: A Rationale for “Transcription Therapy” for Cancer The Keio Journal of Medicine. 48: 123-132. DOI: 10.1007/978-4-431-68506-7_11  0.357
1999 Zhong S, Hu P, Ye TZ, Stan R, Ellis NA, Pandolfi PP. A role for PML and the nuclear body in genomic stability. Oncogene. 18: 7941-7. PMID 10637504 DOI: 10.1038/Sj.Onc.1203367  0.387
1999 Zhong S, Delva L, Rachez C, Cenciarelli C, Gandini D, Zhang H, Kalantry S, Freedman LP, Pandolfi PP. A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins. Nature Genetics. 23: 287-95. PMID 10610177 DOI: 10.1038/15463  0.301
1999 Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, Pelicci PG. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature. 402: 309-13. PMID 10580504 DOI: 10.1038/46311  0.316
1999 Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP. Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell. 99: 323-34. PMID 10555148 DOI: 10.1016/S0092-8674(00)81663-3  0.319
1999 He LZ, Merghoub T, Pandolfi PP. In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications. Oncogene. 18: 5278-92. PMID 10498880 DOI: 10.1038/Sj.Onc.1203088  0.38
1999 Di Cristofano A, Kotsi P, Peng YF, Cordon-Cardo C, Elkon KB, Pandolfi PP. Impaired Fas response and autoimmunity in Pten+/- mice. Science (New York, N.Y.). 285: 2122-5. PMID 10497129 DOI: 10.1126/Science.285.5436.2122  0.391
1999 Harris MB, Chang CC, Berton MT, Danial NN, Zhang J, Kuehner D, Ye BH, Kvatyuk M, Pandolfi PP, Cattoretti G, Dalla-Favera R, Rothman PB. Transcriptional repression of Stat6-dependent interleukin-4-induced genes by BCL-6: specific regulation of iepsilon transcription and immunoglobulin E switching. Molecular and Cellular Biology. 19: 7264-75. PMID 10490661 DOI: 10.1128/Mcb.19.10.7264  0.348
1999 Tremml G, Dominguez C, Rosti V, Zhang Z, Pandolfi P, Keller P, Bessler M. Increased Sensitivity to Complement and a Decreased Red Blood Cell Life Span in Mice Mosaic for a Nonfunctional Piga Gene Blood. 94: 2945-2954. DOI: 10.1182/Blood.V94.9.2945  0.358
1998 Warrell RP, He LZ, Richon V, Calleja E, Pandolfi PP. Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase. Journal of the National Cancer Institute. 90: 1621-5. PMID 9811311 DOI: 10.1093/Jnci/90.21.1621  0.303
1998 Wang ZG, Ruggero D, Ronchetti S, Zhong S, Gaboli M, Rivi R, Pandolfi PP. PML is essential for multiple apoptotic pathways. Nature Genetics. 20: 266-72. PMID 9806545 DOI: 10.1038/3073  0.623
1998 Soignet SL, Maslak P, Wang ZG, Jhanwar S, Calleja E, Dardashti LJ, Corso D, DeBlasio A, Gabrilove J, Scheinberg DA, Pandolfi PP, Warrell RP. Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide New England Journal of Medicine. 339: 1341-1348. PMID 9801394 DOI: 10.1056/Nejm199811053391901  0.321
1998 Wang ZG, Rivi R, Delva L, König A, Scheinberg DA, Gambacorti-Passerini C, Gabrilove JL, Warrell RP, Pandolfi PP. Arsenic trioxide and melarsoprol induce programmed cell death in myeloid leukemia cell lines and function in a PML and PML-RARα independent manner Blood. 92: 1497-1504. PMID 9716575 DOI: 10.1182/Blood.V92.5.1497.417K41_1497_1504  0.356
1998 Di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP. Pten is essential for embryonic development and tumour suppression. Nature Genetics. 19: 348-55. PMID 9697695 DOI: 10.1038/1235  0.383
1998 Gaboli M, Gandini D, Delva L, Wang ZG, Pandolfi PP. Acute promyelocytic leukemia as a model for cross-talk between interferon and retinoic acid pathways: from molecular biology to clinical applications. Leukemia & Lymphoma. 30: 11-22. PMID 9669672 DOI: 10.3109/10428199809050925  0.366
1998 Botto M, Dell'Agnola C, Bygrave AE, Thompson EM, Cook HT, Petry F, Loos M, Pandolfi PP, Walport MJ. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nature Genetics. 19: 56-9. PMID 9590289 DOI: 10.1038/Ng0598-56  0.335
1998 Lembo M, Sacchi C, Zappador C, Bellomo G, Gaboli M, Pandolfi PP, Gariglio M, Landolfo S. Inhibition of cell proliferation by the interferon-inducible 204 gene, a member of the Ifi 200 cluster. Oncogene. 16: 1543-51. PMID 9569021 DOI: 10.1038/Sj.Onc.1201677  0.373
1998 Wang ZG, Delva L, Gaboli M, Rivi R, Giorgio M, Cordon-Cardo C, Grosveld F, Pandolfi PP. Role of PML in cell growth and the retinoic acid pathway. Science (New York, N.Y.). 279: 1547-51. PMID 9488655 DOI: 10.1126/Science.279.5356.1547  0.388
1998 Di Cristofano A, Carpino N, Dunant N, Friedland G, Kobayashi R, Strife A, Wisniewski D, Clarkson B, Pandolfi PP, Resh MD. Molecular cloning and characterization of p56(dok-2) defines a new family of RasGAP-binding proteins Journal of Biological Chemistry. 273: 4827-4830. PMID 9478921 DOI: 10.1074/Jbc.273.9.4827  0.331
1998 He LZ, Guidez F, Tribioli C, Peruzzi D, Ruthardt M, Zelent A, Pandolfi PP. Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL. Nature Genetics. 18: 126-35. PMID 9462740 DOI: 10.1038/Ng0298-126  0.3
1997 Kalantry S, Delva L, Gaboli M, Gandini D, Giorgio M, Hawe N, He LZ, Peruzzi D, Rivi R, Tribioli C, Wang ZG, Zhang H, Pandolfi PP. Gene rearrangements in the molecular pathogenesis of acute promyelocytic leukemia. Journal of Cellular Physiology. 173: 288-96. PMID 9365539 DOI: 10.1002/(Sici)1097-4652(199711)173:2<288::Aid-Jcp38>3.0.Co;2-9  0.328
1997 Longo L, Bygrave A, Grosveld FG, Pandolfi PP. The chromosome make-up of mouse embryonic stem cells is predictive of somatic and germ cell chimaerism. Transgenic Research. 6: 321-8. PMID 9322369 DOI: 10.1023/A:1018418914106  0.332
1997 Rosti V, Tremml G, Soares V, Pandolfi PP, Luzzatto L, Bessler M. Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion. The Journal of Clinical Investigation. 100: 1028-36. PMID 9276719 DOI: 10.1172/Jci119613  0.357
1997 Ye BH, Cattoretti G, Shen Q, Zhang J, Hawe N, de Waard R, Leung C, Nouri-Shirazi M, Orazi A, Chaganti RS, Rothman P, Stall AM, Pandolfi PP, Dalla-Favera R. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nature Genetics. 16: 161-70. PMID 9171827 DOI: 10.1038/Ng0697-161  0.362
1997 He LZ, Tribioli C, Rivi R, Peruzzi D, Pelicci PG, Soares V, Cattoretti G, Pandolfi PP. Acute leukemia with promyelocytic features in PML/RARalpha transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 5302-7. PMID 9144232 DOI: 10.1073/Pnas.94.10.5302  0.335
1997 König A, Wrazel L, Warrell RP, Rivi R, Pandolfi PP, Jakubowski A, Gabrilove JL. Comparative Activity of Melarsoprol and Arsenic Trioxide in Chronic B-Cell Leukemia Lines Blood. 90: 562-570. DOI: 10.1182/Blood.V90.2.562  0.322
1996 Nason-Burchenal K, Gandini D, Botto M, Allopenna J, Seale J, Cross N, Goldman J, Dmitrovsky E, Pandolfi P. Interferon augments PML and PML/RAR alpha expression in normal myeloid and acute promyelocytic cells and cooperates with all-trans retinoic acid to induce maturation of a retinoid-resistant promyelocytic cell line Blood. 88: 3926-3936. DOI: 10.1182/Blood.V88.10.3926.Bloodjournal88103926  0.346
1993 Gambacorti-Passerini C, Grignani F, Arienti F, Pandolfi P, Pelicci P, Parmiani G. Human CD4 lymphocytes specifically recognize a peptide representing the fusion region of the hybrid protein pml/RAR alpha present in acute promyelocytic leukemia cells Blood. 81: 1369-1375. DOI: 10.1182/Blood.V81.5.1369.1369  0.301
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