Mark E. Stearns - Publications

Affiliations: 
Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Cell Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Amatangelo MD, Goodyear S, Varma D, Stearns ME. c-Myc expression and MEK1-induced Erk2 nuclear localization are required for TGF-beta induced epithelial-mesenchymal transition and invasion in prostate cancer. Carcinogenesis. 33: 1965-75. PMID 22791812 DOI: 10.1093/Carcin/Bgs227  0.72
2012 Wang M, Hu Y, Amantagelo MD, Stearns ME. Retraction: Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer. Molecular Cancer Research : McR. 10: 570. PMID 22434856 DOI: 10.1158/1541-7786.Mcr-12-0085  0.72
2012 Amatangelo MD, Stearns ME. Reactivation of epithelial-mesenchymal transition in invasive and metastatic cancer Signaling Pathways and Molecular Mediators in Metastasis. 2147483647: 13-69. DOI: 10.1007/978-94-007-2558-4_2  0.72
2011 Wang M, Hu Y, Amatangelo MD, Stearns ME. Role of ribosomal protein RPS2 in controlling let-7a expression in human prostate cancer. Molecular Cancer Research : McR. 9: 36-50. PMID 21148031 DOI: 10.1158/1541-7786.Mcr-10-0158  0.72
2011 Stearns ME, Wang M. Synergistic effects of the green tea extract epigallocatechin-3-gallate and taxane in eradication of malignant human prostate tumors1 Translational Oncology. 4: 147-156. DOI: 10.1593/tlo.10286  0.72
2010 Stearns ME, Amatangelo MD, Varma D, Sell C, Goodyear SM. Combination therapy with epigallocatechin-3-gallate and doxorubicin in human prostate tumor modeling studies: inhibition of metastatic tumor growth in severe combined immunodeficiency mice. The American Journal of Pathology. 177: 3169-79. PMID 20971741 DOI: 10.2353/Ajpath.2010.100330  0.72
2009 Goodyear SM, Kheyfets SB, Garcia FU, Stearns ME. Role of the VEGFR3/VEGFD receptor axis in TGFbeta1 activation of primary prostate cell lines. The Prostate. 69: 982-90. PMID 19301310 DOI: 10.1002/Pros.20945  0.72
2009 Goodyear SM, Amatangelo MD, Stearns ME. Dysplasia of human prostate CD133(hi) sub-population in NOD-SCIDS is blocked by c-myc anti-sense. The Prostate. 69: 689-98. PMID 19143028 DOI: 10.1002/Pros.20918  0.72
2009 Wang M, Hu Y, Stearns ME. RPS2: a novel therapeutic target in prostate cancer. Journal of Experimental & Clinical Cancer Research : Cr. 28: 6. PMID 19138403 DOI: 10.1186/1756-9966-28-6  0.72
2007 Hu Y, Wang M, Veverka K, Garcia FU, Stearns ME. The ABCA5 protein: a urine diagnostic marker for prostatic intraepithelial neoplasia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 929-38. PMID 17289887 DOI: 10.1158/1078-0432.Ccr-06-1718  0.72
2005 Dolloff NG, Shulby SS, Nelson AV, Stearns ME, Johannes GJ, Thomas JD, Meucci O, Fatatis A. Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha platelet-derived growth factor receptor. Oncogene. 24: 6848-54. PMID 16007172 DOI: 10.1038/Sj.Onc.1208815  0.72
2005 Stearns M, Tran J, Francis MK, Zhang H, Sell C. Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells. Cancer Research. 65: 2085-8. PMID 15781617 DOI: 10.1158/0008-5472.Can-04-4100  0.72
2004 Stearns ME, Kim G, Garcia F, Wang M. Interleukin-10 induced activating transcription factor 3 transcriptional suppression of matrix metalloproteinase-2 gene expression in human prostate CPTX-1532 Cells. Molecular Cancer Research : McR. 2: 403-16. PMID 15280448  0.72
2004 Shulby SA, Dolloff NG, Stearns ME, Meucci O, Fatatis A. CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells. Cancer Research. 64: 4693-8. PMID 15256432 DOI: 10.1158/0008-5472.Can-03-3437  0.72
2004 Stearns ME, Wang M, Hu Y, Kim G, Garcia FU. Expression of a flt-4 (VEGFR3) splicing variant in primary human prostate tumors. VEGF D and flt-4t(Delta773-1081) overexpression is diagnostic for sentinel lymph node metastasis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 84: 785-95. PMID 15107801 DOI: 10.1038/Labinvest.3700075  0.72
2004 Ohkia A, Hu Y, Wang M, Garcia FU, Stearns ME. Evidence for prostate cancer-associated diagnostic marker-1: immunohistochemistry and in situ hybridization studies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2452-8. PMID 15073124 DOI: 10.1158/1078-0432.Ccr-03-0170  0.72
2003 Stearns ME, Wang M, Hu Y, Garcia FU. Interleukin-10 activation of the interleukin-10E1 pathway and tissue inhibitor of metalloproteinase-1 expression is enhanced by proteasome inhibitors in primary prostate tumor lines. Molecular Cancer Research : McR. 1: 631-42. PMID 12861049  0.72
2003 Stearns ME, Hu Y, Wang M. IL-10 signaling via IL-10E1 is dependent on tyrosine phosphorylation in the IL-10R alpha chain in human primary prostate cancer cell lines. Oncogene. 22: 3781-91. PMID 12802285 DOI: 10.1038/Sj.Onc.1206579  0.72
2003 Wang M, Hu Y, Stearns ME. A novel IL-10 signalling mechanism regulates TIMP-1 expression in human prostate tumour cells. British Journal of Cancer. 88: 1605-14. PMID 12771930 DOI: 10.1038/Sj.Bjc.6600855  0.72
2003 Stearns ME, Wang M, Hu Y, Garcia FU, Rhim J. Interleukin 10 blocks matrix metalloproteinase-2 and membrane type 1-matrix metalloproteinase synthesis in primary human prostate tumor lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 1191-9. PMID 12631625  0.72
2000 Garcia FU, Taylor CA, Hou JS, Rukstalis DB, Stearns ME. Increased cellularity of tumor-encased native vessels in prostate carcinoma is a marker for tumor progression. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 13: 717-22. PMID 10912929 DOI: 10.1038/Modpathol.3880124  0.72
1999 Liu XH, Kirschenbaum A, Yao S, Stearns ME, Holland JF, Claffey K, Levine AC. Upregulation of vascular endothelial growth factor by cobalt chloride- simulated hypoxia is mediated by persistent induction of cyclooxygenase-2 in a metastatic human prostate cancer cell line Clinical and Experimental Metastasis. 17: 687-694. PMID 10919714 DOI: 10.1023/A:1006728119549  0.72
1999 Wang M, Liu A, Garcia FU, Rhim JS, Stearns ME. Growth of HPV-18 immortalized human prostatic intraepithelial neoplasia cell lines. Influence of IL-10, follistatin, activin-A, and DHT. International Journal of Oncology. 14: 1185-95. PMID 10339677 DOI: 10.3892/Ijo.14.6.1185  0.72
1998 Stearns ME, Wang M. Alendronate blocks metalloproteinase secretion and bone collagen I release by PC-3 ML cells in SCID mice. Clinical & Experimental Metastasis. 16: 693-702. PMID 10211982 DOI: 10.1023/A:1006524610591  0.72
1998 Stearns ME, Ware JL, Agus DB, Chang CJ, Fidler IJ, Fife RS, Goode R, Holmes E, Kinch MS, Peehl DM, Pretlow TG, Thalmann GN. Workgroup 2: human xenograft models of prostate cancer. The Prostate. 36: 56-8. PMID 9650917 DOI: 10.1002/(Sici)1097-0045(19980615)36:1<56::Aid-Pros10>3.0.Co;2-H  0.72
1998 Stearns ME. Alendronate blocks TGF-beta1 stimulated collagen 1 degradation by human prostate PC-3 ML cells. Clinical & Experimental Metastasis. 16: 332-9. PMID 9626812 DOI: 10.1023/A:1006513413583  0.72
1997 Wood M, Fudge K, Mohler JL, Frost AR, Garcia F, Wang M, Stearns ME. In situ hybridization studies of metalloproteinases 2 and 9 and TIMP-1 and TIMP-2 expression in human prostate cancer. Clinical & Experimental Metastasis. 15: 246-58. PMID 9174126 DOI: 10.1023/A:1018421431388  0.72
1996 Fudge K, Bostwick DG, Stearns ME. Platelet-derived growth factor A and B chains and the alpha and beta receptors in prostatic intraepithelial neoplasia. The Prostate. 29: 282-6. PMID 8899000 DOI: 10.1002/(Sici)1097-0045(199611)29:5<282::Aid-Pros2>3.0.Co;2-C  0.72
1996 McGarvey T, Hussain MM, Stearns ME. In situ hybridization studies of alpha 2-macroglobulin receptor and receptor-associated protein in human prostate carcinoma. The Prostate. 28: 311-7. PMID 8610058 DOI: 10.1002/(Sici)1097-0045(199605)28:5<311::Aid-Pros7>3.0.Co;2-E  0.72
1995 McGarvey TW, Stearns ME. Keratinocyte growth factor and receptor mRNA expression in benign and malignant human prostate. Experimental and Molecular Pathology. 63: 52-62. PMID 8759054 DOI: 10.1006/exmp.1995.1030  0.72
1991 Wang M, Stearns ME. Isolation and characterization of PC-3 human prostatic tumor sublines which preferentially metastasize to select organs in S.C.I.D. mice. Differentiation; Research in Biological Diversity. 48: 115-25. PMID 1773917 DOI: 10.1111/J.1432-0436.1991.Tb00250.X  0.72
1990 Stearns ME, Piazza GA. Properties of kinesin isolated from human prostatic DU 145 tumor cells and bovine brain. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 68: 436-40. PMID 2140513 DOI: 10.1139/o90-061  0.72
1989 Stearns ME, Graybill D. Deprivation/enhancement fantasy patterns in children. Psychological Reports. 65: 127-30. PMID 2780922 DOI: 10.2466/Pr0.1989.65.1.127  0.72
1989 Tew KD, Stearns ME. Estramustine--a nitrogen mustard/steroid with antimicrotubule activity. Pharmacology & Therapeutics. 43: 299-319. PMID 2682681 DOI: 10.1016/0163-7258(89)90012-0  0.72
1988 Stearns ME. Importance of the thiol disulfide status of microtubule proteins for antimitotic drug action. Pharmacology & Therapeutics. 37: 25-36. PMID 3289053 DOI: 10.1016/0163-7258(88)90017-4  0.72
1988 Stearns ME, Wang M, Tew KD, Binder LI. Estramustine binds a MAP-1-like protein to inhibit microtubule assembly in vitro and disrupt microtubule organization in DU 145 cells Journal of Cell Biology. 107: 2647-2656. PMID 3060470  0.72
1987 Stearns ME, Wang M. Evidence for intermediate filaments in squirrelfish erythrophores of Holocentrus ascensionus (Rufus). Experimental Cell Research. 173: 395-412. PMID 3319656 DOI: 10.1016/0014-4827(87)90280-1  0.72
1987 Taylor DW, Parra M, Stearns ME. Plasmodium falciparum: fine structural changes in the cytoskeletons of infected erythrocytes. Experimental Parasitology. 64: 178-87. PMID 3308505 DOI: 10.1016/0014-4894(87)90141-X  0.72
1987 Tew KD, Stearns ME. Hormone-independent, non-alkylating mechanism of cytotoxicity for estramustine. Urological Research. 15: 155-60. PMID 3307087 DOI: 10.1007/BF00254428  0.72
1987 Stearns ME, Binder LI. Evidence that MAP-2 may be involved in pigment granule transport in squirrel fish erythrophores Cell Motility and the Cytoskeleton. 7: 221-234. PMID 3297355  0.72
1987 Taylor DW, Parra M, Chapman GB, Stearns ME, Rener J, Aikawa M, Uni S, Aley SB, Panton LJ, Howard RJ. Localization of Plasmodium falciparum histidine-rich protein 1 in the erythrocyte skeleton under knobs. Molecular and Biochemical Parasitology. 25: 165-74. PMID 2444884 DOI: 10.1016/0166-6851(87)90005-3  0.72
1986 Stearns ME, Binder LI, Wang M. The cytomatrix regulates 'resolute' transport in erythrophores Annals of the New York Academy of Sciences. 895-908. PMID 3460462 DOI: 10.1111/j.1749-6632.1986.tb38475.x  0.72
1985 Stearns ME, Jenkins DP, Tew KD. Dansylated estramustine, a fluorescent probe for studies of estramustine uptake and identification of intracellular targets. Proceedings of the National Academy of Sciences of the United States of America. 82: 8483-7. PMID 3866236 DOI: 10.1073/pnas.82.24.8483  0.72
1984 Stearns ME. Cytomatrix in chromatophores. The Journal of Cell Biology. 99: 144s-151s. PMID 6235232 DOI: 10.1083/jcb.99.1.144s  0.72
1981 Stearns ME, Brown DL. Microtubule organizing centers (MTOCs) of the alga Polytomella exert spatial control over microtubule initiation in vivo and in vitro. Journal of Ultrastructure Research. 77: 366-78. PMID 7198693 DOI: 10.1016/S0022-5320(81)80033-0  0.72
1979 Stearns ME, Brown DL. Purification of a microtubule-associated protein based on its preferential association with tubulin during microtubule initiation. Febs Letters. 101: 15-20. PMID 446728 DOI: 10.1016/0014-5793(79)81285-5  0.72
1979 Stearns ME, Brown DL. Purification of cytoplasmic tubulin and microtubule organizing center proteins functioning in microtubule initiation from the alga Polytomella. Proceedings of the National Academy of Sciences of the United States of America. 76: 5745-9. PMID 293678 DOI: 10.1073/pnas.76.11.5745  0.72
1976 Stearns ME, Connolly JA, Brown DL. Cytoplasmic microtubule organizing centers isolated from Polytomella agilis. Science (New York, N.Y.). 191: 188-91. PMID 1246607 DOI: 10.1126/science.1246607  0.72
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